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Network neighborhood for query Sequence : DDX49_HUMAN

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DDX49_HUMAN
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX49_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	223	Target Neighborhood Hits	223	Shared Neighborhood Hits	223
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	0 (rank : 2)	NC score	0.995465 (rank : 2)
Query Neighborhood Hits	223	Target Neighborhood Hits	119	Shared Neighborhood Hits	109
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_MOUSE
θ value	1.48926e-103 (rank : 3)	NC score	0.987630 (rank : 3)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
θ value	4.79078e-102 (rank : 4)	NC score	0.987263 (rank : 4)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX27_HUMAN
θ value	3.83135e-67 (rank : 5)	NC score	0.972115 (rank : 6)
Query Neighborhood Hits	223	Target Neighborhood Hits	197	Shared Neighborhood Hits	99
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	1.45591e-66 (rank : 6)	NC score	0.973045 (rank : 5)
Query Neighborhood Hits	223	Target Neighborhood Hits	174	Shared Neighborhood Hits	92
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX54_MOUSE
θ value	5.0155e-59 (rank : 7)	NC score	0.967088 (rank : 9)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
θ value	2.10721e-57 (rank : 8)	NC score	0.964015 (rank : 10)
Query Neighborhood Hits	223	Target Neighborhood Hits	170	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX46_HUMAN
θ value	1.78386e-56 (rank : 9)	NC score	0.947390 (rank : 48)
Query Neighborhood Hits	223	Target Neighborhood Hits	357	Shared Neighborhood Hits	113
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	1.78386e-56 (rank : 10)	NC score	0.945180 (rank : 52)
Query Neighborhood Hits	223	Target Neighborhood Hits	358	Shared Neighborhood Hits	112
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX23_HUMAN
θ value	2.84797e-54 (rank : 11)	NC score	0.940685 (rank : 58)
Query Neighborhood Hits	223	Target Neighborhood Hits	486	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX17_HUMAN
θ value	1.19655e-52 (rank : 12)	NC score	0.960265 (rank : 16)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.19655e-52 (rank : 13)	NC score	0.960402 (rank : 15)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX18_MOUSE
θ value	2.66562e-52 (rank : 14)	NC score	0.961066 (rank : 13)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX10_HUMAN
θ value	2.25659e-51 (rank : 15)	NC score	0.955826 (rank : 34)
Query Neighborhood Hits	223	Target Neighborhood Hits	210	Shared Neighborhood Hits	93
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	8.57503e-51 (rank : 16)	NC score	0.956012 (rank : 33)
Query Neighborhood Hits	223	Target Neighborhood Hits	233	Shared Neighborhood Hits	93
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
θ value	5.55816e-50 (rank : 17)	NC score	0.959622 (rank : 21)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX6_HUMAN
θ value	9.48078e-50 (rank : 18)	NC score	0.967459 (rank : 7)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	9.48078e-50 (rank : 19)	NC score	0.967272 (rank : 8)
Query Neighborhood Hits	223	Target Neighborhood Hits	98	Shared Neighborhood Hits	88
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX39_HUMAN
θ value	4.70527e-49 (rank : 20)	NC score	0.959758 (rank : 20)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	88
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX31_HUMAN
θ value	1.788e-48 (rank : 21)	NC score	0.959934 (rank : 18)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX48_HUMAN
θ value	1.788e-48 (rank : 22)	NC score	0.960012 (rank : 17)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	2.3352e-48 (rank : 23)	NC score	0.959818 (rank : 19)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX5_HUMAN
θ value	2.3352e-48 (rank : 24)	NC score	0.955053 (rank : 40)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	3.98324e-48 (rank : 25)	NC score	0.955026 (rank : 41)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX4_MOUSE
θ value	8.87376e-48 (rank : 26)	NC score	0.958308 (rank : 25)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	92
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX39_MOUSE
θ value	1.15895e-47 (rank : 27)	NC score	0.958978 (rank : 22)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX3Y_MOUSE
θ value	1.97686e-47 (rank : 28)	NC score	0.948761 (rank : 44)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	91
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

UAP56_HUMAN
θ value	2.58187e-47 (rank : 29)	NC score	0.957951 (rank : 26)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	88
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	2.58187e-47 (rank : 30)	NC score	0.957896 (rank : 27)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

PL10_MOUSE
θ value	3.37202e-47 (rank : 31)	NC score	0.948475 (rank : 45)
Query Neighborhood Hits	223	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
θ value	7.51208e-47 (rank : 32)	NC score	0.948081 (rank : 46)
Query Neighborhood Hits	223	Target Neighborhood Hits	122	Shared Neighborhood Hits	89
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX4_HUMAN
θ value	1.28137e-46 (rank : 33)	NC score	0.957132 (rank : 29)
Query Neighborhood Hits	223	Target Neighborhood Hits	123	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX3X_MOUSE
θ value	6.35935e-46 (rank : 34)	NC score	0.947392 (rank : 47)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	89
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

IF4A1_HUMAN
θ value	6.35935e-46 (rank : 35)	NC score	0.956146 (rank : 31)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	91
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	6.35935e-46 (rank : 36)	NC score	0.956146 (rank : 32)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	91
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX41_HUMAN
θ value	1.08474e-45 (rank : 37)	NC score	0.963261 (rank : 11)
Query Neighborhood Hits	223	Target Neighborhood Hits	111	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	4.122e-45 (rank : 38)	NC score	0.962712 (rank : 12)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	93
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX43_HUMAN
θ value	7.03111e-45 (rank : 39)	NC score	0.960938 (rank : 14)
Query Neighborhood Hits	223	Target Neighborhood Hits	120	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX3Y_HUMAN
θ value	1.19932e-44 (rank : 40)	NC score	0.945979 (rank : 50)
Query Neighborhood Hits	223	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

IF4A2_HUMAN
θ value	2.26182e-43 (rank : 41)	NC score	0.955759 (rank : 35)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	92
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	2.26182e-43 (rank : 42)	NC score	0.955759 (rank : 36)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	92
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX53_HUMAN
θ value	5.03882e-43 (rank : 43)	NC score	0.953951 (rank : 43)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX24_HUMAN
θ value	1.79215e-40 (rank : 44)	NC score	0.943132 (rank : 54)
Query Neighborhood Hits	223	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX51_MOUSE
θ value	3.05695e-40 (rank : 45)	NC score	0.946246 (rank : 49)
Query Neighborhood Hits	223	Target Neighborhood Hits	130	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX56_HUMAN
θ value	5.21438e-40 (rank : 46)	NC score	0.955551 (rank : 37)
Query Neighborhood Hits	223	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX24_MOUSE
θ value	2.58786e-39 (rank : 47)	NC score	0.945779 (rank : 51)
Query Neighborhood Hits	223	Target Neighborhood Hits	147	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX20_MOUSE
θ value	4.41421e-39 (rank : 48)	NC score	0.940806 (rank : 57)
Query Neighborhood Hits	223	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX56_MOUSE
θ value	4.41421e-39 (rank : 49)	NC score	0.954774 (rank : 42)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX51_HUMAN
θ value	5.76516e-39 (rank : 50)	NC score	0.931194 (rank : 63)
Query Neighborhood Hits	223	Target Neighborhood Hits	332	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX55_MOUSE
θ value	9.83387e-39 (rank : 51)	NC score	0.956860 (rank : 30)
Query Neighborhood Hits	223	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX28_HUMAN
θ value	2.19075e-38 (rank : 52)	NC score	0.955130 (rank : 38)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX20_HUMAN
θ value	1.85459e-37 (rank : 53)	NC score	0.943418 (rank : 53)
Query Neighborhood Hits	223	Target Neighborhood Hits	121	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX52_HUMAN
θ value	9.20422e-37 (rank : 54)	NC score	0.958830 (rank : 23)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_HUMAN
θ value	1.20211e-36 (rank : 55)	NC score	0.955094 (rank : 39)
Query Neighborhood Hits	223	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX52_MOUSE
θ value	2.05049e-36 (rank : 56)	NC score	0.958536 (rank : 24)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DD19A_MOUSE
θ value	4.568e-36 (rank : 57)	NC score	0.931666 (rank : 60)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
θ value	5.96599e-36 (rank : 58)	NC score	0.932370 (rank : 59)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX28_MOUSE
θ value	1.01765e-35 (rank : 59)	NC score	0.957652 (rank : 28)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DD19B_HUMAN
θ value	1.73584e-35 (rank : 60)	NC score	0.931573 (rank : 62)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX50_MOUSE
θ value	2.96089e-35 (rank : 61)	NC score	0.942664 (rank : 55)
Query Neighborhood Hits	223	Target Neighborhood Hits	137	Shared Neighborhood Hits	92
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
θ value	6.59618e-35 (rank : 62)	NC score	0.942464 (rank : 56)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_HUMAN
θ value	2.77131e-33 (rank : 63)	NC score	0.931106 (rank : 64)
Query Neighborhood Hits	223	Target Neighborhood Hits	308	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_MOUSE
θ value	4.72714e-33 (rank : 64)	NC score	0.922528 (rank : 66)
Query Neighborhood Hits	223	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX25_HUMAN
θ value	5.77852e-31 (rank : 65)	NC score	0.931618 (rank : 61)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	2.19584e-30 (rank : 66)	NC score	0.930575 (rank : 65)
Query Neighborhood Hits	223	Target Neighborhood Hits	98	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX1_HUMAN
θ value	5.23862e-24 (rank : 67)	NC score	0.888446 (rank : 68)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	8.93572e-24 (rank : 68)	NC score	0.889840 (rank : 67)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

RECQ4_HUMAN
θ value	4.76016e-09 (rank : 69)	NC score	0.570171 (rank : 69)
Query Neighborhood Hits	223	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

BLM_MOUSE
θ value	5.26297e-08 (rank : 70)	NC score	0.523874 (rank : 71)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
θ value	1.53129e-07 (rank : 71)	NC score	0.511009 (rank : 72)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	79
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ1_HUMAN
θ value	7.59969e-07 (rank : 72)	NC score	0.460151 (rank : 75)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	9.92553e-07 (rank : 73)	NC score	0.457995 (rank : 76)
Query Neighborhood Hits	223	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_HUMAN
θ value	4.1701e-05 (rank : 74)	NC score	0.484959 (rank : 73)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

FANCM_MOUSE
θ value	0.000270298 (rank : 75)	NC score	0.436728 (rank : 79)
Query Neighborhood Hits	223	Target Neighborhood Hits	177	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

FANCM_HUMAN
θ value	0.00035302 (rank : 76)	NC score	0.440888 (rank : 78)
Query Neighborhood Hits	223	Target Neighborhood Hits	210	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

LGP2_HUMAN
θ value	0.00035302 (rank : 77)	NC score	0.340811 (rank : 84)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

RECQ4_MOUSE
θ value	0.000461057 (rank : 78)	NC score	0.547179 (rank : 70)
Query Neighborhood Hits	223	Target Neighborhood Hits	206	Shared Neighborhood Hits	96
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BAZ2A_MOUSE
θ value	0.00390308 (rank : 79)	NC score	0.027723 (rank : 106)
Query Neighborhood Hits	223	Target Neighborhood Hits	744	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

IFIH1_MOUSE
θ value	0.00390308 (rank : 80)	NC score	0.331790 (rank : 85)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

WRN_MOUSE
θ value	0.00390308 (rank : 81)	NC score	0.448355 (rank : 77)
Query Neighborhood Hits	223	Target Neighborhood Hits	295	Shared Neighborhood Hits	91
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

LGP2_MOUSE
θ value	0.00509761 (rank : 82)	NC score	0.351020 (rank : 82)
Query Neighborhood Hits	223	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

CAF1A_MOUSE
θ value	0.0148317 (rank : 83)	NC score	0.032819 (rank : 101)
Query Neighborhood Hits	223	Target Neighborhood Hits	736	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

IFIH1_HUMAN
θ value	0.0148317 (rank : 84)	NC score	0.342907 (rank : 83)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

DHX29_MOUSE
θ value	0.0193708 (rank : 85)	NC score	0.053711 (rank : 95)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

SAFB2_HUMAN
θ value	0.0193708 (rank : 86)	NC score	0.021472 (rank : 114)
Query Neighborhood Hits	223	Target Neighborhood Hits	720	Shared Neighborhood Hits	53
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

DHX36_HUMAN
θ value	0.0252991 (rank : 87)	NC score	0.040159 (rank : 98)
Query Neighborhood Hits	223	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

SMCA2_HUMAN
θ value	0.0252991 (rank : 88)	NC score	0.028196 (rank : 105)
Query Neighborhood Hits	223	Target Neighborhood Hits	503	Shared Neighborhood Hits	51
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

DHX29_HUMAN
θ value	0.0330416 (rank : 89)	NC score	0.053491 (rank : 96)
Query Neighborhood Hits	223	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DICER_MOUSE
θ value	0.0330416 (rank : 90)	NC score	0.404950 (rank : 81)
Query Neighborhood Hits	223	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DHX36_MOUSE
θ value	0.0431538 (rank : 91)	NC score	0.041497 (rank : 97)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DICER_HUMAN
θ value	0.0431538 (rank : 92)	NC score	0.405329 (rank : 80)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

TRI16_HUMAN
θ value	0.0431538 (rank : 93)	NC score	0.011947 (rank : 170)
Query Neighborhood Hits	223	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

CAF1A_HUMAN
θ value	0.125558 (rank : 94)	NC score	0.029021 (rank : 103)
Query Neighborhood Hits	223	Target Neighborhood Hits	750	Shared Neighborhood Hits	55
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

INCE_MOUSE
θ value	0.163984 (rank : 95)	NC score	0.020492 (rank : 116)
Query Neighborhood Hits	223	Target Neighborhood Hits	903	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MYO5C_HUMAN
θ value	0.163984 (rank : 96)	NC score	0.016672 (rank : 125)
Query Neighborhood Hits	223	Target Neighborhood Hits	1206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PLCB2_HUMAN
θ value	0.163984 (rank : 97)	NC score	0.020720 (rank : 115)
Query Neighborhood Hits	223	Target Neighborhood Hits	608	Shared Neighborhood Hits	66
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

BASP_HUMAN
θ value	0.21417 (rank : 98)	NC score	0.019976 (rank : 117)
Query Neighborhood Hits	223	Target Neighborhood Hits	321	Shared Neighborhood Hits	14
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CHD1_HUMAN
θ value	0.279714 (rank : 99)	NC score	0.036229 (rank : 99)
Query Neighborhood Hits	223	Target Neighborhood Hits	337	Shared Neighborhood Hits	33
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	0.279714 (rank : 100)	NC score	0.036194 (rank : 100)
Query Neighborhood Hits	223	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

REN3A_HUMAN
θ value	0.365318 (rank : 101)	NC score	0.024102 (rank : 107)
Query Neighborhood Hits	223	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

AXN1_MOUSE
θ value	0.47712 (rank : 102)	NC score	0.009922 (rank : 189)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

BAZ2B_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.023553 (rank : 110)
Query Neighborhood Hits	223	Target Neighborhood Hits	803	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

SMCA1_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.029431 (rank : 102)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

U520_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.149134 (rank : 89)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CCD39_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.014709 (rank : 139)
Query Neighborhood Hits	223	Target Neighborhood Hits	868	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

DDX58_MOUSE
θ value	0.62314 (rank : 107)	NC score	0.220943 (rank : 86)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	66
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

GOGA3_HUMAN
θ value	0.62314 (rank : 108)	NC score	0.012316 (rank : 163)
Query Neighborhood Hits	223	Target Neighborhood Hits	1317	Shared Neighborhood Hits	74
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

ITSN1_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.014027 (rank : 145)
Query Neighborhood Hits	223	Target Neighborhood Hits	1669	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KINH_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.016177 (rank : 128)
Query Neighborhood Hits	223	Target Neighborhood Hits	1231	Shared Neighborhood Hits	87
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MAP1B_MOUSE
θ value	0.62314 (rank : 111)	NC score	0.009368 (rank : 192)
Query Neighborhood Hits	223	Target Neighborhood Hits	977	Shared Neighborhood Hits	49
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SCN8A_MOUSE
θ value	0.62314 (rank : 112)	NC score	0.011670 (rank : 174)
Query Neighborhood Hits	223	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

ZRF1_HUMAN
θ value	0.62314 (rank : 113)	NC score	0.015362 (rank : 131)
Query Neighborhood Hits	223	Target Neighborhood Hits	457	Shared Neighborhood Hits	40
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

BAZ2A_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.023561 (rank : 109)
Query Neighborhood Hits	223	Target Neighborhood Hits	780	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

HELC1_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.113755 (rank : 91)
Query Neighborhood Hits	223	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

MYH10_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.013791 (rank : 148)
Query Neighborhood Hits	223	Target Neighborhood Hits	1620	Shared Neighborhood Hits	90
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	0.813845 (rank : 117)	NC score	0.014036 (rank : 144)
Query Neighborhood Hits	223	Target Neighborhood Hits	1612	Shared Neighborhood Hits	90
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PEPL_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.014511 (rank : 141)
Query Neighborhood Hits	223	Target Neighborhood Hits	1141	Shared Neighborhood Hits	77
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

RECQ5_HUMAN
θ value	0.813845 (rank : 119)	NC score	0.469505 (rank : 74)
Query Neighborhood Hits	223	Target Neighborhood Hits	390	Shared Neighborhood Hits	87
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SCN1A_HUMAN
θ value	0.813845 (rank : 120)	NC score	0.011151 (rank : 178)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

TAOK3_HUMAN
θ value	0.813845 (rank : 121)	NC score	0.000531 (rank : 219)
Query Neighborhood Hits	223	Target Neighborhood Hits	1494	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

F10A5_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.011841 (rank : 171)
Query Neighborhood Hits	223	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

MY18A_MOUSE
θ value	1.06291 (rank : 123)	NC score	0.022820 (rank : 111)
Query Neighborhood Hits	223	Target Neighborhood Hits	1989	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TAOK3_MOUSE
θ value	1.06291 (rank : 124)	NC score	-0.000013 (rank : 221)
Query Neighborhood Hits	223	Target Neighborhood Hits	1458	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

AFAD_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.010473 (rank : 186)
Query Neighborhood Hits	223	Target Neighborhood Hits	689	Shared Neighborhood Hits	49
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CYTSA_HUMAN
θ value	1.38821 (rank : 126)	NC score	0.017830 (rank : 123)
Query Neighborhood Hits	223	Target Neighborhood Hits	1138	Shared Neighborhood Hits	81
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

INCE_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.018612 (rank : 122)
Query Neighborhood Hits	223	Target Neighborhood Hits	978	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

ITSN1_HUMAN
θ value	1.38821 (rank : 128)	NC score	0.011266 (rank : 176)
Query Neighborhood Hits	223	Target Neighborhood Hits	1757	Shared Neighborhood Hits	91
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MYO6_HUMAN
θ value	1.38821 (rank : 129)	NC score	0.011981 (rank : 169)
Query Neighborhood Hits	223	Target Neighborhood Hits	727	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

PCLO_HUMAN
θ value	1.38821 (rank : 130)	NC score	0.008818 (rank : 195)
Query Neighborhood Hits	223	Target Neighborhood Hits	2046	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SCN2A_HUMAN
θ value	1.38821 (rank : 131)	NC score	0.011806 (rank : 172)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

DIAP1_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.008022 (rank : 196)
Query Neighborhood Hits	223	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

NAF1_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.016363 (rank : 127)
Query Neighborhood Hits	223	Target Neighborhood Hits	937	Shared Neighborhood Hits	76
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NFM_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.005883 (rank : 203)
Query Neighborhood Hits	223	Target Neighborhood Hits	1328	Shared Neighborhood Hits	73
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SCN8A_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.010862 (rank : 183)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

STK10_MOUSE
θ value	1.81305 (rank : 136)	NC score	0.006073 (rank : 201)
Query Neighborhood Hits	223	Target Neighborhood Hits	2132	Shared Neighborhood Hits	109
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ANR12_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.009124 (rank : 194)
Query Neighborhood Hits	223	Target Neighborhood Hits	1081	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BCN1_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.016654 (rank : 126)
Query Neighborhood Hits	223	Target Neighborhood Hits	395	Shared Neighborhood Hits	51
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

DNJC8_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.021617 (rank : 113)
Query Neighborhood Hits	223	Target Neighborhood Hits	392	Shared Neighborhood Hits	57
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

GAK4_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.012954 (rank : 156)
Query Neighborhood Hits	223	Target Neighborhood Hits	415	Shared Neighborhood Hits	21
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SMCA1_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.055333 (rank : 94)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

AKAP9_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.013343 (rank : 151)
Query Neighborhood Hits	223	Target Neighborhood Hits	1710	Shared Neighborhood Hits	92
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CENPE_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.011029 (rank : 179)
Query Neighborhood Hits	223	Target Neighborhood Hits	2060	Shared Neighborhood Hits	100
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DDX58_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.186251 (rank : 87)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	64
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

FLIP1_HUMAN
θ value	3.0926 (rank : 145)	NC score	0.019364 (rank : 120)
Query Neighborhood Hits	223	Target Neighborhood Hits	1405	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA1_MOUSE
θ value	3.0926 (rank : 146)	NC score	0.012300 (rank : 164)
Query Neighborhood Hits	223	Target Neighborhood Hits	994	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MBD3_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.007220 (rank : 198)
Query Neighborhood Hits	223	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MINK1_HUMAN
θ value	3.0926 (rank : 148)	NC score	-0.003670 (rank : 225)
Query Neighborhood Hits	223	Target Neighborhood Hits	1477	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	3.0926 (rank : 149)	NC score	-0.003707 (rank : 226)
Query Neighborhood Hits	223	Target Neighborhood Hits	1451	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYH11_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.014757 (rank : 138)
Query Neighborhood Hits	223	Target Neighborhood Hits	1806	Shared Neighborhood Hits	101
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NUMA1_HUMAN
θ value	3.0926 (rank : 151)	NC score	0.009134 (rank : 193)
Query Neighborhood Hits	223	Target Neighborhood Hits	1523	Shared Neighborhood Hits	80
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PTN23_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.001692 (rank : 218)
Query Neighborhood Hits	223	Target Neighborhood Hits	726	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RRS1_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.013733 (rank : 149)
Query Neighborhood Hits	223	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q15050, Q9BUX8	Gene names	RRS1, KIAA0112, RRR
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

TAF3_MOUSE
θ value	3.0926 (rank : 154)	NC score	0.010185 (rank : 187)
Query Neighborhood Hits	223	Target Neighborhood Hits	463	Shared Neighborhood Hits	41
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TXLNA_MOUSE
θ value	3.0926 (rank : 155)	NC score	0.014098 (rank : 143)
Query Neighborhood Hits	223	Target Neighborhood Hits	846	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ZC313_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.028618 (rank : 104)
Query Neighborhood Hits	223	Target Neighborhood Hits	772	Shared Neighborhood Hits	75
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CASP7_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.005630 (rank : 205)
Query Neighborhood Hits	223	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P55210, Q13364, Q96BA0	Gene names	CASP7, MCH3
Domain Architecture
Description	Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].

GAK5_HUMAN
θ value	4.03905 (rank : 158)	NC score	0.012602 (rank : 160)
Query Neighborhood Hits	223	Target Neighborhood Hits	429	Shared Neighborhood Hits	22
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK9_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.013950 (rank : 146)
Query Neighborhood Hits	223	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

ITSN2_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.010981 (rank : 180)
Query Neighborhood Hits	223	Target Neighborhood Hits	1371	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

JAD1C_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.005417 (rank : 206)
Query Neighborhood Hits	223	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

MYH9_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.017041 (rank : 124)
Query Neighborhood Hits	223	Target Neighborhood Hits	1762	Shared Neighborhood Hits	98
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PEPL_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.015305 (rank : 132)
Query Neighborhood Hits	223	Target Neighborhood Hits	1105	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PHF3_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.013872 (rank : 147)
Query Neighborhood Hits	223	Target Neighborhood Hits	419	Shared Neighborhood Hits	38
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PLDN_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.011992 (rank : 168)
Query Neighborhood Hits	223	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

SAKS1_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.011179 (rank : 177)
Query Neighborhood Hits	223	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SCN3A_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.010058 (rank : 188)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

TAOK1_HUMAN
θ value	4.03905 (rank : 168)	NC score	0.004427 (rank : 211)
Query Neighborhood Hits	223	Target Neighborhood Hits	1734	Shared Neighborhood Hits	87
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TRDN_HUMAN
θ value	4.03905 (rank : 169)	NC score	0.013329 (rank : 152)
Query Neighborhood Hits	223	Target Neighborhood Hits	542	Shared Neighborhood Hits	38
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRHY_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.013150 (rank : 153)
Query Neighborhood Hits	223	Target Neighborhood Hits	1385	Shared Neighborhood Hits	68
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ARHG6_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.004154 (rank : 212)
Query Neighborhood Hits	223	Target Neighborhood Hits	376	Shared Neighborhood Hits	26
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

BRE1A_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.010865 (rank : 182)
Query Neighborhood Hits	223	Target Neighborhood Hits	1071	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.010517 (rank : 185)
Query Neighborhood Hits	223	Target Neighborhood Hits	1025	Shared Neighborhood Hits	62
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BSN_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.010981 (rank : 181)
Query Neighborhood Hits	223	Target Neighborhood Hits	1537	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DNJC8_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.019522 (rank : 119)
Query Neighborhood Hits	223	Target Neighborhood Hits	380	Shared Neighborhood Hits	56
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

EI2BD_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.005717 (rank : 204)
Query Neighborhood Hits	223	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

GAK1_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.013059 (rank : 155)
Query Neighborhood Hits	223	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

KINH_MOUSE
θ value	5.27518 (rank : 178)	NC score	0.014885 (rank : 136)
Query Neighborhood Hits	223	Target Neighborhood Hits	1082	Shared Neighborhood Hits	84
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MD1L1_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.015443 (rank : 130)
Query Neighborhood Hits	223	Target Neighborhood Hits	893	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

PININ_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.019660 (rank : 118)
Query Neighborhood Hits	223	Target Neighborhood Hits	753	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	5.27518 (rank : 181)	NC score	0.023950 (rank : 108)
Query Neighborhood Hits	223	Target Neighborhood Hits	777	Shared Neighborhood Hits	80
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RRS1_MOUSE
θ value	5.27518 (rank : 182)	NC score	0.013138 (rank : 154)
Query Neighborhood Hits	223	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CYH6, Q3UQW6, Q9CS27, Q9D2B2, Q9D6M6, Q9JJC1	Gene names	Rrs1, Rrr
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

TXLNA_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.015045 (rank : 134)
Query Neighborhood Hits	223	Target Neighborhood Hits	982	Shared Neighborhood Hits	72
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

AXN1_HUMAN
θ value	6.88961 (rank : 184)	NC score	0.006809 (rank : 199)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

CO9_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.003009 (rank : 215)
Query Neighborhood Hits	223	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.002956 (rank : 216)
Query Neighborhood Hits	223	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CP135_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.014656 (rank : 140)
Query Neighborhood Hits	223	Target Neighborhood Hits	1278	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CTRO_HUMAN
θ value	6.88961 (rank : 188)	NC score	-0.000065 (rank : 223)
Query Neighborhood Hits	223	Target Neighborhood Hits	2092	Shared Neighborhood Hits	80
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DAAM1_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.005176 (rank : 208)
Query Neighborhood Hits	223	Target Neighborhood Hits	443	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

F10C1_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.006310 (rank : 200)
Query Neighborhood Hits	223	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q70Z53, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8	Gene names	FRA10AC1, C10orf4
Domain Architecture	No domain graphic available
Description	Protein FRA10AC1.

GAK10_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.012789 (rank : 158)
Query Neighborhood Hits	223	Target Neighborhood Hits	289	Shared Neighborhood Hits	19
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.012186 (rank : 166)
Query Neighborhood Hits	223	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.012451 (rank : 162)
Query Neighborhood Hits	223	Target Neighborhood Hits	374	Shared Neighborhood Hits	22
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK17_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.013378 (rank : 150)
Query Neighborhood Hits	223	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK2_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.012186 (rank : 167)
Query Neighborhood Hits	223	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.012199 (rank : 165)
Query Neighborhood Hits	223	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HOOK2_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.009876 (rank : 191)
Query Neighborhood Hits	223	Target Neighborhood Hits	714	Shared Neighborhood Hits	61
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

MY18A_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.022164 (rank : 112)
Query Neighborhood Hits	223	Target Neighborhood Hits	1929	Shared Neighborhood Hits	108
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH11_MOUSE
θ value	6.88961 (rank : 199)	NC score	0.015903 (rank : 129)
Query Neighborhood Hits	223	Target Neighborhood Hits	1777	Shared Neighborhood Hits	100
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
θ value	6.88961 (rank : 200)	NC score	0.018939 (rank : 121)
Query Neighborhood Hits	223	Target Neighborhood Hits	1829	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TITIN_HUMAN
θ value	6.88961 (rank : 201)	NC score	-0.007304 (rank : 227)
Query Neighborhood Hits	223	Target Neighborhood Hits	2923	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI30_MOUSE
θ value	6.88961 (rank : 202)	NC score	-0.000171 (rank : 224)
Query Neighborhood Hits	223	Target Neighborhood Hits	434	Shared Neighborhood Hits	26
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

ARHG6_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.005887 (rank : 202)
Query Neighborhood Hits	223	Target Neighborhood Hits	394	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

BAZ1B_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.010600 (rank : 184)
Query Neighborhood Hits	223	Target Neighborhood Hits	394	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BCN1_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.014110 (rank : 142)
Query Neighborhood Hits	223	Target Neighborhood Hits	367	Shared Neighborhood Hits	47
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

BRD4_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.007992 (rank : 197)
Query Neighborhood Hits	223	Target Neighborhood Hits	851	Shared Neighborhood Hits	57
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BSN_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.004809 (rank : 210)
Query Neighborhood Hits	223	Target Neighborhood Hits	2057	Shared Neighborhood Hits	69
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CTRO_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.005133 (rank : 209)
Query Neighborhood Hits	223	Target Neighborhood Hits	2344	Shared Neighborhood Hits	93
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CYTSA_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.015169 (rank : 133)
Query Neighborhood Hits	223	Target Neighborhood Hits	1104	Shared Neighborhood Hits	80
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

FLIP1_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.014921 (rank : 135)
Query Neighborhood Hits	223	Target Neighborhood Hits	1176	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FRM4A_MOUSE
θ value	8.99809 (rank : 211)	NC score	-0.000015 (rank : 222)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

GAK3_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.012828 (rank : 157)
Query Neighborhood Hits	223	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HM2L1_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.002451 (rank : 217)
Query Neighborhood Hits	223	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

IF2P_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.011433 (rank : 175)
Query Neighborhood Hits	223	Target Neighborhood Hits	889	Shared Neighborhood Hits	61
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF3A_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.014782 (rank : 137)
Query Neighborhood Hits	223	Target Neighborhood Hits	871	Shared Neighborhood Hits	74
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

LRC59_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.000007 (rank : 220)
Query Neighborhood Hits	223	Target Neighborhood Hits	415	Shared Neighborhood Hits	23
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

MMTA2_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.005261 (rank : 207)
Query Neighborhood Hits	223	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LX5, Q9CSK6	Gene names	Mmtag2
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 homolog.

NOG1_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.003488 (rank : 213)
Query Neighborhood Hits	223	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

PHLB2_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.011773 (rank : 173)
Query Neighborhood Hits	223	Target Neighborhood Hits	964	Shared Neighborhood Hits	76
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	8.99809 (rank : 220)	NC score	0.012563 (rank : 161)
Query Neighborhood Hits	223	Target Neighborhood Hits	1016	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RBP1_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.003250 (rank : 214)
Query Neighborhood Hits	223	Target Neighborhood Hits	521	Shared Neighborhood Hits	38
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SAKS1_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.009900 (rank : 190)
Query Neighborhood Hits	223	Target Neighborhood Hits	202	Shared Neighborhood Hits	27
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

ZRF1_MOUSE
θ value	8.99809 (rank : 223)	NC score	0.012706 (rank : 159)
Query Neighborhood Hits	223	Target Neighborhood Hits	414	Shared Neighborhood Hits	45
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

CC026_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.157297 (rank : 88)
Query Neighborhood Hits	223	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.126661 (rank : 90)
Query Neighborhood Hits	223	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

SMAL1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.080297 (rank : 92)
Query Neighborhood Hits	223	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.055795 (rank : 93)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

Hits sorted by NC score

DDX49_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	223	Target Neighborhood Hits	223	Shared Neighborhood Hits	223
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
NC score	0.995465 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	223	Target Neighborhood Hits	119	Shared Neighborhood Hits	109
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_MOUSE
NC score	0.987630 (rank : 3)	θ value	1.48926e-103 (rank : 3)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.987263 (rank : 4)	θ value	4.79078e-102 (rank : 4)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX27_MOUSE
NC score	0.973045 (rank : 5)	θ value	1.45591e-66 (rank : 6)
Query Neighborhood Hits	223	Target Neighborhood Hits	174	Shared Neighborhood Hits	92
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.972115 (rank : 6)	θ value	3.83135e-67 (rank : 5)
Query Neighborhood Hits	223	Target Neighborhood Hits	197	Shared Neighborhood Hits	99
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX6_HUMAN
NC score	0.967459 (rank : 7)	θ value	9.48078e-50 (rank : 18)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.967272 (rank : 8)	θ value	9.48078e-50 (rank : 19)
Query Neighborhood Hits	223	Target Neighborhood Hits	98	Shared Neighborhood Hits	88
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX54_MOUSE
NC score	0.967088 (rank : 9)	θ value	5.0155e-59 (rank : 7)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
NC score	0.964015 (rank : 10)	θ value	2.10721e-57 (rank : 8)
Query Neighborhood Hits	223	Target Neighborhood Hits	170	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX41_HUMAN
NC score	0.963261 (rank : 11)	θ value	1.08474e-45 (rank : 37)
Query Neighborhood Hits	223	Target Neighborhood Hits	111	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.962712 (rank : 12)	θ value	4.122e-45 (rank : 38)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	93
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX18_MOUSE
NC score	0.961066 (rank : 13)	θ value	2.66562e-52 (rank : 14)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX43_HUMAN
NC score	0.960938 (rank : 14)	θ value	7.03111e-45 (rank : 39)
Query Neighborhood Hits	223	Target Neighborhood Hits	120	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX17_MOUSE
NC score	0.960402 (rank : 15)	θ value	1.19655e-52 (rank : 13)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.960265 (rank : 16)	θ value	1.19655e-52 (rank : 12)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX48_HUMAN
NC score	0.960012 (rank : 17)	θ value	1.788e-48 (rank : 22)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX31_HUMAN
NC score	0.959934 (rank : 18)	θ value	1.788e-48 (rank : 21)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX48_MOUSE
NC score	0.959818 (rank : 19)	θ value	2.3352e-48 (rank : 23)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX39_HUMAN
NC score	0.959758 (rank : 20)	θ value	4.70527e-49 (rank : 20)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	88
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX18_HUMAN
NC score	0.959622 (rank : 21)	θ value	5.55816e-50 (rank : 17)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX39_MOUSE
NC score	0.958978 (rank : 22)	θ value	1.15895e-47 (rank : 27)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX52_HUMAN
NC score	0.958830 (rank : 23)	θ value	9.20422e-37 (rank : 54)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
NC score	0.958536 (rank : 24)	θ value	2.05049e-36 (rank : 56)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX4_MOUSE
NC score	0.958308 (rank : 25)	θ value	8.87376e-48 (rank : 26)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	92
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

UAP56_HUMAN
NC score	0.957951 (rank : 26)	θ value	2.58187e-47 (rank : 29)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	88
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.957896 (rank : 27)	θ value	2.58187e-47 (rank : 30)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX28_MOUSE
NC score	0.957652 (rank : 28)	θ value	1.01765e-35 (rank : 59)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX4_HUMAN
NC score	0.957132 (rank : 29)	θ value	1.28137e-46 (rank : 33)
Query Neighborhood Hits	223	Target Neighborhood Hits	123	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX55_MOUSE
NC score	0.956860 (rank : 30)	θ value	9.83387e-39 (rank : 51)
Query Neighborhood Hits	223	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

IF4A1_HUMAN
NC score	0.956146 (rank : 31)	θ value	6.35935e-46 (rank : 35)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	91
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.956146 (rank : 32)	θ value	6.35935e-46 (rank : 36)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	91
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX10_MOUSE
NC score	0.956012 (rank : 33)	θ value	8.57503e-51 (rank : 16)
Query Neighborhood Hits	223	Target Neighborhood Hits	233	Shared Neighborhood Hits	93
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_HUMAN
NC score	0.955826 (rank : 34)	θ value	2.25659e-51 (rank : 15)
Query Neighborhood Hits	223	Target Neighborhood Hits	210	Shared Neighborhood Hits	93
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

IF4A2_HUMAN
NC score	0.955759 (rank : 35)	θ value	2.26182e-43 (rank : 41)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	92
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.955759 (rank : 36)	θ value	2.26182e-43 (rank : 42)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	92
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX56_HUMAN
NC score	0.955551 (rank : 37)	θ value	5.21438e-40 (rank : 46)
Query Neighborhood Hits	223	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX28_HUMAN
NC score	0.955130 (rank : 38)	θ value	2.19075e-38 (rank : 52)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX55_HUMAN
NC score	0.955094 (rank : 39)	θ value	1.20211e-36 (rank : 55)
Query Neighborhood Hits	223	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX5_HUMAN
NC score	0.955053 (rank : 40)	θ value	2.3352e-48 (rank : 24)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.955026 (rank : 41)	θ value	3.98324e-48 (rank : 25)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX56_MOUSE
NC score	0.954774 (rank : 42)	θ value	4.41421e-39 (rank : 49)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX53_HUMAN
NC score	0.953951 (rank : 43)	θ value	5.03882e-43 (rank : 43)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX3Y_MOUSE
NC score	0.948761 (rank : 44)	θ value	1.97686e-47 (rank : 28)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	91
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

PL10_MOUSE
NC score	0.948475 (rank : 45)	θ value	3.37202e-47 (rank : 31)
Query Neighborhood Hits	223	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.948081 (rank : 46)	θ value	7.51208e-47 (rank : 32)
Query Neighborhood Hits	223	Target Neighborhood Hits	122	Shared Neighborhood Hits	89
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
NC score	0.947392 (rank : 47)	θ value	6.35935e-46 (rank : 34)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	89
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX46_HUMAN
NC score	0.947390 (rank : 48)	θ value	1.78386e-56 (rank : 9)
Query Neighborhood Hits	223	Target Neighborhood Hits	357	Shared Neighborhood Hits	113
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX51_MOUSE
NC score	0.946246 (rank : 49)	θ value	3.05695e-40 (rank : 45)
Query Neighborhood Hits	223	Target Neighborhood Hits	130	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX3Y_HUMAN
NC score	0.945979 (rank : 50)	θ value	1.19932e-44 (rank : 40)
Query Neighborhood Hits	223	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX24_MOUSE
NC score	0.945779 (rank : 51)	θ value	2.58786e-39 (rank : 47)
Query Neighborhood Hits	223	Target Neighborhood Hits	147	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX46_MOUSE
NC score	0.945180 (rank : 52)	θ value	1.78386e-56 (rank : 10)
Query Neighborhood Hits	223	Target Neighborhood Hits	358	Shared Neighborhood Hits	112
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX20_HUMAN
NC score	0.943418 (rank : 53)	θ value	1.85459e-37 (rank : 53)
Query Neighborhood Hits	223	Target Neighborhood Hits	121	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX24_HUMAN
NC score	0.943132 (rank : 54)	θ value	1.79215e-40 (rank : 44)
Query Neighborhood Hits	223	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX50_MOUSE
NC score	0.942664 (rank : 55)	θ value	2.96089e-35 (rank : 61)
Query Neighborhood Hits	223	Target Neighborhood Hits	137	Shared Neighborhood Hits	92
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
NC score	0.942464 (rank : 56)	θ value	6.59618e-35 (rank : 62)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX20_MOUSE
NC score	0.940806 (rank : 57)	θ value	4.41421e-39 (rank : 48)
Query Neighborhood Hits	223	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX23_HUMAN
NC score	0.940685 (rank : 58)	θ value	2.84797e-54 (rank : 11)
Query Neighborhood Hits	223	Target Neighborhood Hits	486	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DD19A_HUMAN
NC score	0.932370 (rank : 59)	θ value	5.96599e-36 (rank : 58)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
NC score	0.931666 (rank : 60)	θ value	4.568e-36 (rank : 57)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_HUMAN
NC score	0.931618 (rank : 61)	θ value	5.77852e-31 (rank : 65)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19B_HUMAN
NC score	0.931573 (rank : 62)	θ value	1.73584e-35 (rank : 60)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX51_HUMAN
NC score	0.931194 (rank : 63)	θ value	5.76516e-39 (rank : 50)
Query Neighborhood Hits	223	Target Neighborhood Hits	332	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX21_HUMAN
NC score	0.931106 (rank : 64)	θ value	2.77131e-33 (rank : 63)
Query Neighborhood Hits	223	Target Neighborhood Hits	308	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX25_MOUSE
NC score	0.930575 (rank : 65)	θ value	2.19584e-30 (rank : 66)
Query Neighborhood Hits	223	Target Neighborhood Hits	98	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX21_MOUSE
NC score	0.922528 (rank : 66)	θ value	4.72714e-33 (rank : 64)
Query Neighborhood Hits	223	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX1_MOUSE
NC score	0.889840 (rank : 67)	θ value	8.93572e-24 (rank : 68)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.888446 (rank : 68)	θ value	5.23862e-24 (rank : 67)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.570171 (rank : 69)	θ value	4.76016e-09 (rank : 69)
Query Neighborhood Hits	223	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.547179 (rank : 70)	θ value	0.000461057 (rank : 78)
Query Neighborhood Hits	223	Target Neighborhood Hits	206	Shared Neighborhood Hits	96
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.523874 (rank : 71)	θ value	5.26297e-08 (rank : 70)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.511009 (rank : 72)	θ value	1.53129e-07 (rank : 71)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	79
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
NC score	0.484959 (rank : 73)	θ value	4.1701e-05 (rank : 74)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ5_HUMAN
NC score	0.469505 (rank : 74)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	223	Target Neighborhood Hits	390	Shared Neighborhood Hits	87
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ1_HUMAN
NC score	0.460151 (rank : 75)	θ value	7.59969e-07 (rank : 72)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.457995 (rank : 76)	θ value	9.92553e-07 (rank : 73)
Query Neighborhood Hits	223	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_MOUSE
NC score	0.448355 (rank : 77)	θ value	0.00390308 (rank : 81)
Query Neighborhood Hits	223	Target Neighborhood Hits	295	Shared Neighborhood Hits	91
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

FANCM_HUMAN
NC score	0.440888 (rank : 78)	θ value	0.00035302 (rank : 76)
Query Neighborhood Hits	223	Target Neighborhood Hits	210	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.436728 (rank : 79)	θ value	0.000270298 (rank : 75)
Query Neighborhood Hits	223	Target Neighborhood Hits	177	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_HUMAN
NC score	0.405329 (rank : 80)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.404950 (rank : 81)	θ value	0.0330416 (rank : 90)
Query Neighborhood Hits	223	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

LGP2_MOUSE
NC score	0.351020 (rank : 82)	θ value	0.00509761 (rank : 82)
Query Neighborhood Hits	223	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_HUMAN
NC score	0.342907 (rank : 83)	θ value	0.0148317 (rank : 84)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.340811 (rank : 84)	θ value	0.00035302 (rank : 77)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_MOUSE
NC score	0.331790 (rank : 85)	θ value	0.00390308 (rank : 80)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.220943 (rank : 86)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	66
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.186251 (rank : 87)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	64
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_HUMAN
NC score	0.157297 (rank : 88)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	223	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

U520_HUMAN
NC score	0.149134 (rank : 89)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_MOUSE
NC score	0.126661 (rank : 90)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	223	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

HELC1_HUMAN
NC score	0.113755 (rank : 91)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	223	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
NC score	0.080297 (rank : 92)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	223	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
NC score	0.055795 (rank : 93)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_MOUSE
NC score	0.055333 (rank : 94)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

DHX29_MOUSE
NC score	0.053711 (rank : 95)	θ value	0.0193708 (rank : 85)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX29_HUMAN
NC score	0.053491 (rank : 96)	θ value	0.0330416 (rank : 89)
Query Neighborhood Hits	223	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX36_MOUSE
NC score	0.041497 (rank : 97)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_HUMAN
NC score	0.040159 (rank : 98)	θ value	0.0252991 (rank : 87)
Query Neighborhood Hits	223	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

CHD1_HUMAN
NC score	0.036229 (rank : 99)	θ value	0.279714 (rank : 99)
Query Neighborhood Hits	223	Target Neighborhood Hits	337	Shared Neighborhood Hits	33
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.036194 (rank : 100)	θ value	0.279714 (rank : 100)
Query Neighborhood Hits	223	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CAF1A_MOUSE
NC score	0.032819 (rank : 101)	θ value	0.0148317 (rank : 83)
Query Neighborhood Hits	223	Target Neighborhood Hits	736	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

SMCA1_HUMAN
NC score	0.029431 (rank : 102)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

CAF1A_HUMAN
NC score	0.029021 (rank : 103)	θ value	0.125558 (rank : 94)
Query Neighborhood Hits	223	Target Neighborhood Hits	750	Shared Neighborhood Hits	55
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ZC313_HUMAN
NC score	0.028618 (rank : 104)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	223	Target Neighborhood Hits	772	Shared Neighborhood Hits	75
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

SMCA2_HUMAN
NC score	0.028196 (rank : 105)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	223	Target Neighborhood Hits	503	Shared Neighborhood Hits	51
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

BAZ2A_MOUSE
NC score	0.027723 (rank : 106)	θ value	0.00390308 (rank : 79)
Query Neighborhood Hits	223	Target Neighborhood Hits	744	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

REN3A_HUMAN
NC score	0.024102 (rank : 107)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	223	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

PININ_MOUSE
NC score	0.023950 (rank : 108)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	223	Target Neighborhood Hits	777	Shared Neighborhood Hits	80
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

BAZ2A_HUMAN
NC score	0.023561 (rank : 109)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	223	Target Neighborhood Hits	780	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2B_HUMAN
NC score	0.023553 (rank : 110)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	223	Target Neighborhood Hits	803	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MY18A_MOUSE
NC score	0.022820 (rank : 111)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	223	Target Neighborhood Hits	1989	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_HUMAN
NC score	0.022164 (rank : 112)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	223	Target Neighborhood Hits	1929	Shared Neighborhood Hits	108
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

DNJC8_MOUSE
NC score	0.021617 (rank : 113)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	223	Target Neighborhood Hits	392	Shared Neighborhood Hits	57
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

SAFB2_HUMAN
NC score	0.021472 (rank : 114)	θ value	0.0193708 (rank : 86)
Query Neighborhood Hits	223	Target Neighborhood Hits	720	Shared Neighborhood Hits	53
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

PLCB2_HUMAN
NC score	0.020720 (rank : 115)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	223	Target Neighborhood Hits	608	Shared Neighborhood Hits	66
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

INCE_MOUSE
NC score	0.020492 (rank : 116)	θ value	0.163984 (rank : 95)
Query Neighborhood Hits	223	Target Neighborhood Hits	903	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

BASP_HUMAN
NC score	0.019976 (rank : 117)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	223	Target Neighborhood Hits	321	Shared Neighborhood Hits	14
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

PININ_HUMAN
NC score	0.019660 (rank : 118)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	223	Target Neighborhood Hits	753	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

DNJC8_HUMAN
NC score	0.019522 (rank : 119)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	223	Target Neighborhood Hits	380	Shared Neighborhood Hits	56
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

FLIP1_HUMAN
NC score	0.019364 (rank : 120)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	223	Target Neighborhood Hits	1405	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MYH9_MOUSE
NC score	0.018939 (rank : 121)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	223	Target Neighborhood Hits	1829	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

INCE_HUMAN
NC score	0.018612 (rank : 122)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	223	Target Neighborhood Hits	978	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

CYTSA_HUMAN
NC score	0.017830 (rank : 123)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	223	Target Neighborhood Hits	1138	Shared Neighborhood Hits	81
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

MYH9_HUMAN
NC score	0.017041 (rank : 124)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	223	Target Neighborhood Hits	1762	Shared Neighborhood Hits	98
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO5C_HUMAN
NC score	0.016672 (rank : 125)	θ value	0.163984 (rank : 96)
Query Neighborhood Hits	223	Target Neighborhood Hits	1206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

BCN1_HUMAN
NC score	0.016654 (rank : 126)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	223	Target Neighborhood Hits	395	Shared Neighborhood Hits	51
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

NAF1_HUMAN
NC score	0.016363 (rank : 127)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	223	Target Neighborhood Hits	937	Shared Neighborhood Hits	76
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

KINH_HUMAN
NC score	0.016177 (rank : 128)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	223	Target Neighborhood Hits	1231	Shared Neighborhood Hits	87
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MYH11_MOUSE
NC score	0.015903 (rank : 129)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	223	Target Neighborhood Hits	1777	Shared Neighborhood Hits	100
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MD1L1_HUMAN
NC score	0.015443 (rank : 130)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	223	Target Neighborhood Hits	893	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

ZRF1_HUMAN
NC score	0.015362 (rank : 131)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	223	Target Neighborhood Hits	457	Shared Neighborhood Hits	40
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

PEPL_MOUSE
NC score	0.015305 (rank : 132)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	223	Target Neighborhood Hits	1105	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CYTSA_MOUSE
NC score	0.015169 (rank : 133)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	223	Target Neighborhood Hits	1104	Shared Neighborhood Hits	80
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

TXLNA_HUMAN
NC score	0.015045 (rank : 134)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	223	Target Neighborhood Hits	982	Shared Neighborhood Hits	72
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

FLIP1_MOUSE
NC score	0.014921 (rank : 135)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	223	Target Neighborhood Hits	1176	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

KINH_MOUSE
NC score	0.014885 (rank : 136)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	223	Target Neighborhood Hits	1082	Shared Neighborhood Hits	84
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

IF3A_MOUSE
NC score	0.014782 (rank : 137)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	223	Target Neighborhood Hits	871	Shared Neighborhood Hits	74
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MYH11_HUMAN
NC score	0.014757 (rank : 138)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	223	Target Neighborhood Hits	1806	Shared Neighborhood Hits	101
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CCD39_HUMAN
NC score	0.014709 (rank : 139)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	223	Target Neighborhood Hits	868	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CP135_MOUSE
NC score	0.014656 (rank : 140)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	223	Target Neighborhood Hits	1278	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

PEPL_HUMAN
NC score	0.014511 (rank : 141)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	223	Target Neighborhood Hits	1141	Shared Neighborhood Hits	77
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

BCN1_MOUSE
NC score	0.014110 (rank : 142)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	223	Target Neighborhood Hits	367	Shared Neighborhood Hits	47
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

TXLNA_MOUSE
NC score	0.014098 (rank : 143)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	223	Target Neighborhood Hits	846	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

MYH10_MOUSE
NC score	0.014036 (rank : 144)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	223	Target Neighborhood Hits	1612	Shared Neighborhood Hits	90
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ITSN1_MOUSE
NC score	0.014027 (rank : 145)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	223	Target Neighborhood Hits	1669	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

GAK9_HUMAN
NC score	0.013950 (rank : 146)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	223	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

PHF3_HUMAN
NC score	0.013872 (rank : 147)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	223	Target Neighborhood Hits	419	Shared Neighborhood Hits	38
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

MYH10_HUMAN
NC score	0.013791 (rank : 148)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	223	Target Neighborhood Hits	1620	Shared Neighborhood Hits	90
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RRS1_HUMAN
NC score	0.013733 (rank : 149)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	223	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q15050, Q9BUX8	Gene names	RRS1, KIAA0112, RRR
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

GAK17_HUMAN
NC score	0.013378 (rank : 150)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	223	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

AKAP9_HUMAN
NC score	0.013343 (rank : 151)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	223	Target Neighborhood Hits	1710	Shared Neighborhood Hits	92
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

TRDN_HUMAN
NC score	0.013329 (rank : 152)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	223	Target Neighborhood Hits	542	Shared Neighborhood Hits	38
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRHY_HUMAN
NC score	0.013150 (rank : 153)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	223	Target Neighborhood Hits	1385	Shared Neighborhood Hits	68
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

RRS1_MOUSE
NC score	0.013138 (rank : 154)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	223	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CYH6, Q3UQW6, Q9CS27, Q9D2B2, Q9D6M6, Q9JJC1	Gene names	Rrs1, Rrr
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

GAK1_HUMAN
NC score	0.013059 (rank : 155)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	223	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.012954 (rank : 156)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	223	Target Neighborhood Hits	415	Shared Neighborhood Hits	21
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK3_HUMAN
NC score	0.012828 (rank : 157)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	223	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK10_HUMAN
NC score	0.012789 (rank : 158)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	223	Target Neighborhood Hits	289	Shared Neighborhood Hits	19
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ZRF1_MOUSE
NC score	0.012706 (rank : 159)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	223	Target Neighborhood Hits	414	Shared Neighborhood Hits	45
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

GAK5_HUMAN
NC score	0.012602 (rank : 160)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	223	Target Neighborhood Hits	429	Shared Neighborhood Hits	22
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PHLB2_MOUSE
NC score	0.012563 (rank : 161)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	223	Target Neighborhood Hits	1016	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

GAK12_HUMAN
NC score	0.012451 (rank : 162)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	223	Target Neighborhood Hits	374	Shared Neighborhood Hits	22
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GOGA3_HUMAN
NC score	0.012316 (rank : 163)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	223	Target Neighborhood Hits	1317	Shared Neighborhood Hits	74
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA1_MOUSE
NC score	0.012300 (rank : 164)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	223	Target Neighborhood Hits	994	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GAK6_HUMAN
NC score	0.012199 (rank : 165)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	223	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.012186 (rank : 166)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	223	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.012186 (rank : 167)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	223	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PLDN_HUMAN
NC score	0.011992 (rank : 168)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	223	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

MYO6_HUMAN
NC score	0.011981 (rank : 169)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	223	Target Neighborhood Hits	727	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

TRI16_HUMAN
NC score	0.011947 (rank : 170)	θ value	0.0431538 (rank : 93)
Query Neighborhood Hits	223	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

F10A5_HUMAN
NC score	0.011841 (rank : 171)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	223	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

SCN2A_HUMAN
NC score	0.011806 (rank : 172)	θ value	1.38821 (rank : 131)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

PHLB2_HUMAN
NC score	0.011773 (rank : 173)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	223	Target Neighborhood Hits	964	Shared Neighborhood Hits	76
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SCN8A_MOUSE
NC score	0.011670 (rank : 174)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	223	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

IF2P_HUMAN
NC score	0.011433 (rank : 175)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	223	Target Neighborhood Hits	889	Shared Neighborhood Hits	61
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

ITSN1_HUMAN
NC score	0.011266 (rank : 176)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	223	Target Neighborhood Hits	1757	Shared Neighborhood Hits	91
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SAKS1_MOUSE
NC score	0.011179 (rank : 177)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	223	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SCN1A_HUMAN
NC score	0.011151 (rank : 178)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CENPE_HUMAN
NC score	0.011029 (rank : 179)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	223	Target Neighborhood Hits	2060	Shared Neighborhood Hits	100
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ITSN2_MOUSE
NC score	0.010981 (rank : 180)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	223	Target Neighborhood Hits	1371	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

BSN_HUMAN
NC score	0.010981 (rank : 181)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	223	Target Neighborhood Hits	1537	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BRE1A_HUMAN
NC score	0.010865 (rank : 182)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	223	Target Neighborhood Hits	1071	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

SCN8A_HUMAN
NC score	0.010862 (rank : 183)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

BAZ1B_MOUSE
NC score	0.010600 (rank : 184)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	223	Target Neighborhood Hits	394	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BRE1A_MOUSE
NC score	0.010517 (rank : 185)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	223	Target Neighborhood Hits	1025	Shared Neighborhood Hits	62
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

AFAD_HUMAN
NC score	0.010473 (rank : 186)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	223	Target Neighborhood Hits	689	Shared Neighborhood Hits	49
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

TAF3_MOUSE
NC score	0.010185 (rank : 187)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	223	Target Neighborhood Hits	463	Shared Neighborhood Hits	41
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SCN3A_HUMAN
NC score	0.010058 (rank : 188)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

AXN1_MOUSE
NC score	0.009922 (rank : 189)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

SAKS1_HUMAN
NC score	0.009900 (rank : 190)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	223	Target Neighborhood Hits	202	Shared Neighborhood Hits	27
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

HOOK2_HUMAN
NC score	0.009876 (rank : 191)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	223	Target Neighborhood Hits	714	Shared Neighborhood Hits	61
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

MAP1B_MOUSE
NC score	0.009368 (rank : 192)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	223	Target Neighborhood Hits	977	Shared Neighborhood Hits	49
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NUMA1_HUMAN
NC score	0.009134 (rank : 193)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	223	Target Neighborhood Hits	1523	Shared Neighborhood Hits	80
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ANR12_HUMAN
NC score	0.009124 (rank : 194)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	223	Target Neighborhood Hits	1081	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

PCLO_HUMAN
NC score	0.008818 (rank : 195)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	223	Target Neighborhood Hits	2046	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DIAP1_HUMAN
NC score	0.008022 (rank : 196)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	223	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

BRD4_HUMAN
NC score	0.007992 (rank : 197)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	223	Target Neighborhood Hits	851	Shared Neighborhood Hits	57
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MBD3_HUMAN
NC score	0.007220 (rank : 198)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	223	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

AXN1_HUMAN
NC score	0.006809 (rank : 199)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

F10C1_HUMAN
NC score	0.006310 (rank : 200)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	223	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q70Z53, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8	Gene names	FRA10AC1, C10orf4
Domain Architecture	No domain graphic available
Description	Protein FRA10AC1.

STK10_MOUSE
NC score	0.006073 (rank : 201)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	223	Target Neighborhood Hits	2132	Shared Neighborhood Hits	109
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ARHG6_MOUSE
NC score	0.005887 (rank : 202)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	223	Target Neighborhood Hits	394	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

NFM_HUMAN
NC score	0.005883 (rank : 203)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	223	Target Neighborhood Hits	1328	Shared Neighborhood Hits	73
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

EI2BD_HUMAN
NC score	0.005717 (rank : 204)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	223	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

CASP7_HUMAN
NC score	0.005630 (rank : 205)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	223	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P55210, Q13364, Q96BA0	Gene names	CASP7, MCH3
Domain Architecture
Description	Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].

JAD1C_HUMAN
NC score	0.005417 (rank : 206)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	223	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

MMTA2_MOUSE
NC score	0.005261 (rank : 207)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	223	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LX5, Q9CSK6	Gene names	Mmtag2
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 homolog.

DAAM1_MOUSE
NC score	0.005176 (rank : 208)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	223	Target Neighborhood Hits	443	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

CTRO_MOUSE
NC score	0.005133 (rank : 209)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	223	Target Neighborhood Hits	2344	Shared Neighborhood Hits	93
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

BSN_MOUSE
NC score	0.004809 (rank : 210)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	223	Target Neighborhood Hits	2057	Shared Neighborhood Hits	69
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

TAOK1_HUMAN
NC score	0.004427 (rank : 211)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	223	Target Neighborhood Hits	1734	Shared Neighborhood Hits	87
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

ARHG6_HUMAN
NC score	0.004154 (rank : 212)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	223	Target Neighborhood Hits	376	Shared Neighborhood Hits	26
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

NOG1_HUMAN
NC score	0.003488 (rank : 213)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	223	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

RBP1_HUMAN
NC score	0.003250 (rank : 214)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	223	Target Neighborhood Hits	521	Shared Neighborhood Hits	38
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CO9_HUMAN
NC score	0.003009 (rank : 215)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	223	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
NC score	0.002956 (rank : 216)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	223	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

HM2L1_HUMAN
NC score	0.002451 (rank : 217)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	223	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

PTN23_MOUSE
NC score	0.001692 (rank : 218)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	223	Target Neighborhood Hits	726	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

TAOK3_HUMAN
NC score	0.000531 (rank : 219)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	223	Target Neighborhood Hits	1494	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

LRC59_MOUSE
NC score	0.000007 (rank : 220)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	223	Target Neighborhood Hits	415	Shared Neighborhood Hits	23
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

TAOK3_MOUSE
NC score	-0.000013 (rank : 221)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	223	Target Neighborhood Hits	1458	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

FRM4A_MOUSE
NC score	-0.000015 (rank : 222)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

CTRO_HUMAN
NC score	-0.000065 (rank : 223)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	223	Target Neighborhood Hits	2092	Shared Neighborhood Hits	80
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

TRI30_MOUSE
NC score	-0.000171 (rank : 224)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	223	Target Neighborhood Hits	434	Shared Neighborhood Hits	26
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

MINK1_HUMAN
NC score	-0.003670 (rank : 225)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	223	Target Neighborhood Hits	1477	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
NC score	-0.003707 (rank : 226)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	223	Target Neighborhood Hits	1451	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

TITIN_HUMAN
NC score	-0.007304 (rank : 227)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	223	Target Neighborhood Hits	2923	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).