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Network neighborhood for query Sequence : CC026_MOUSE

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CC026_MOUSE
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CC026_MOUSE
θ value	2.19974e-139 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CC026_HUMAN
θ value	7.35691e-119 (rank : 2)	NC score	0.981589 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX39_MOUSE
θ value	0.000602161 (rank : 3)	NC score	0.202053 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

UAP56_HUMAN
θ value	0.000602161 (rank : 4)	NC score	0.203369 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.000602161 (rank : 5)	NC score	0.203369 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX39_HUMAN
θ value	0.00134147 (rank : 6)	NC score	0.198653 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	94	Shared Neighborhood Hits	27
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX1_HUMAN
θ value	0.0961366 (rank : 7)	NC score	0.175600 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX24_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.147605 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX1_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.170819 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX20_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.166549 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	0.279714 (rank : 11)	NC score	0.166551 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX3X_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.153933 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.152931 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	120	Shared Neighborhood Hits	27
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.152678 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	122	Shared Neighborhood Hits	27
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.153314 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3Y_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.153255 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

ANKR6_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.014166 (rank : 84)
Query Neighborhood Hits	38	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ATX1_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.050147 (rank : 79)
Query Neighborhood Hits	38	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

DDX54_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.133451 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

POP1_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.057276 (rank : 75)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q99575, Q15037	Gene names	POP1, KIAA0061
Domain Architecture
Description	Ribonucleases P/MRP protein subunit POP1 (EC 3.1.26.5) (hPOP1).

SFRIP_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.039292 (rank : 81)
Query Neighborhood Hits	38	Target Neighborhood Hits	530	Shared Neighborhood Hits	8
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

DDX21_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.137563 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

SHD_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.020054 (rank : 82)
Query Neighborhood Hits	38	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

ADDB_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.016214 (rank : 83)
Query Neighborhood Hits	38	Target Neighborhood Hits	574	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

DDX24_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.139676 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	147	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX56_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.126150 (rank : 52)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

GRAP1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.008909 (rank : 87)
Query Neighborhood Hits	38	Target Neighborhood Hits	944	Shared Neighborhood Hits	5
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

ATX1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.047133 (rank : 80)
Query Neighborhood Hits	38	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

DDX21_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.134528 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	350	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

T3JAM_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.013865 (rank : 85)
Query Neighborhood Hits	38	Target Neighborhood Hits	533	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

DDX41_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.135390 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	111	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.135241 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX48_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.141727 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.141731 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

IF4A1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.143625 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.143625 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

NEB1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.007707 (rank : 88)
Query Neighborhood Hits	38	Target Neighborhood Hits	829	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

WBS14_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.013292 (rank : 86)
Query Neighborhood Hits	38	Target Neighborhood Hits	273	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

BLM_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.061270 (rank : 73)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.066769 (rank : 71)
Query Neighborhood Hits	38	Target Neighborhood Hits	108	Shared Neighborhood Hits	24
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

DD19A_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.130677 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.130772 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.130947 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX10_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.117709 (rank : 66)
Query Neighborhood Hits	38	Target Neighborhood Hits	210	Shared Neighborhood Hits	26
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.118017 (rank : 64)
Query Neighborhood Hits	38	Target Neighborhood Hits	233	Shared Neighborhood Hits	26
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX17_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.129706 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	104	Shared Neighborhood Hits	26
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.129735 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX18_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.117116 (rank : 67)
Query Neighborhood Hits	38	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX18_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.117988 (rank : 65)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX23_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.125024 (rank : 54)
Query Neighborhood Hits	38	Target Neighborhood Hits	486	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX25_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.127543 (rank : 46)
Query Neighborhood Hits	38	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.128071 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX27_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.126989 (rank : 49)
Query Neighborhood Hits	38	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.126765 (rank : 50)
Query Neighborhood Hits	38	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX28_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.121761 (rank : 59)
Query Neighborhood Hits	38	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX28_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.122144 (rank : 57)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX31_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.115012 (rank : 69)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX43_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.125672 (rank : 53)
Query Neighborhood Hits	38	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX46_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.121867 (rank : 58)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.121455 (rank : 62)
Query Neighborhood Hits	38	Target Neighborhood Hits	358	Shared Neighborhood Hits	27
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX47_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.127693 (rank : 45)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.127944 (rank : 44)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.126661 (rank : 51)
Query Neighborhood Hits	38	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.129055 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX4_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.128286 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.128032 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	100	Shared Neighborhood Hits	25
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX50_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.130328 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.130948 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX51_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.109797 (rank : 70)
Query Neighborhood Hits	38	Target Neighborhood Hits	332	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.116102 (rank : 68)
Query Neighborhood Hits	38	Target Neighborhood Hits	130	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX52_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.122760 (rank : 55)
Query Neighborhood Hits	38	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.121759 (rank : 60)
Query Neighborhood Hits	38	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX53_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.128356 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX54_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.128061 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX55_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.121556 (rank : 61)
Query Neighborhood Hits	38	Target Neighborhood Hits	122	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.122722 (rank : 56)
Query Neighborhood Hits	38	Target Neighborhood Hits	111	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.121209 (rank : 63)
Query Neighborhood Hits	38	Target Neighborhood Hits	87	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX5_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.127272 (rank : 48)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	26
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.127386 (rank : 47)
Query Neighborhood Hits	38	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX6_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.137888 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	26
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.137793 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	26
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

FANCM_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.052541 (rank : 78)
Query Neighborhood Hits	38	Target Neighborhood Hits	210	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

IF4A2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.135649 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.135649 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

RECQ4_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.063571 (rank : 72)
Query Neighborhood Hits	38	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.060852 (rank : 74)
Query Neighborhood Hits	38	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

WRN_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.055196 (rank : 76)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	24
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.054387 (rank : 77)
Query Neighborhood Hits	38	Target Neighborhood Hits	295	Shared Neighborhood Hits	24
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

Hits sorted by NC score

CC026_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.19974e-139 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CC026_HUMAN
NC score	0.981589 (rank : 2)	θ value	7.35691e-119 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

UAP56_HUMAN
NC score	0.203369 (rank : 3)	θ value	0.000602161 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.203369 (rank : 4)	θ value	0.000602161 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX39_MOUSE
NC score	0.202053 (rank : 5)	θ value	0.000602161 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX39_HUMAN
NC score	0.198653 (rank : 6)	θ value	0.00134147 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	94	Shared Neighborhood Hits	27
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX1_HUMAN
NC score	0.175600 (rank : 7)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
NC score	0.170819 (rank : 8)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX20_MOUSE
NC score	0.166551 (rank : 9)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX20_HUMAN
NC score	0.166549 (rank : 10)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX3X_MOUSE
NC score	0.153933 (rank : 11)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
NC score	0.153314 (rank : 12)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3Y_MOUSE
NC score	0.153255 (rank : 13)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

PL10_MOUSE
NC score	0.152931 (rank : 14)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	120	Shared Neighborhood Hits	27
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.152678 (rank : 15)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	122	Shared Neighborhood Hits	27
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX24_HUMAN
NC score	0.147605 (rank : 16)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

IF4A1_HUMAN
NC score	0.143625 (rank : 17)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.143625 (rank : 18)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX48_MOUSE
NC score	0.141731 (rank : 19)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX48_HUMAN
NC score	0.141727 (rank : 20)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX24_MOUSE
NC score	0.139676 (rank : 21)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	147	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX6_HUMAN
NC score	0.137888 (rank : 22)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	26
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.137793 (rank : 23)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	26
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX21_HUMAN
NC score	0.137563 (rank : 24)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

IF4A2_HUMAN
NC score	0.135649 (rank : 25)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.135649 (rank : 26)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX41_HUMAN
NC score	0.135390 (rank : 27)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	111	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.135241 (rank : 28)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX21_MOUSE
NC score	0.134528 (rank : 29)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	350	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX54_HUMAN
NC score	0.133451 (rank : 30)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX50_MOUSE
NC score	0.130948 (rank : 31)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	38	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DD19B_HUMAN
NC score	0.130947 (rank : 32)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.130772 (rank : 33)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
NC score	0.130677 (rank : 34)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX50_HUMAN
NC score	0.130328 (rank : 35)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX17_MOUSE
NC score	0.129735 (rank : 36)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	38	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.129706 (rank : 37)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	38	Target Neighborhood Hits	104	Shared Neighborhood Hits	26
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX49_MOUSE
NC score	0.129055 (rank : 38)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	38	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX53_HUMAN
NC score	0.128356 (rank : 39)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	38	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX4_HUMAN
NC score	0.128286 (rank : 40)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	38	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX25_MOUSE
NC score	0.128071 (rank : 41)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX54_MOUSE
NC score	0.128061 (rank : 42)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	38	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX4_MOUSE
NC score	0.128032 (rank : 43)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	38	Target Neighborhood Hits	100	Shared Neighborhood Hits	25
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX47_MOUSE
NC score	0.127944 (rank : 44)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.127693 (rank : 45)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX25_HUMAN
NC score	0.127543 (rank : 46)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	38	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX5_MOUSE
NC score	0.127386 (rank : 47)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	38	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.127272 (rank : 48)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	26
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX27_HUMAN
NC score	0.126989 (rank : 49)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	38	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
NC score	0.126765 (rank : 50)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	38	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX49_HUMAN
NC score	0.126661 (rank : 51)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	38	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX56_HUMAN
NC score	0.126150 (rank : 52)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX43_HUMAN
NC score	0.125672 (rank : 53)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	38	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX23_HUMAN
NC score	0.125024 (rank : 54)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	38	Target Neighborhood Hits	486	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX52_HUMAN
NC score	0.122760 (rank : 55)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	38	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_MOUSE
NC score	0.122722 (rank : 56)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	38	Target Neighborhood Hits	111	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX28_MOUSE
NC score	0.122144 (rank : 57)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX46_HUMAN
NC score	0.121867 (rank : 58)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX28_HUMAN
NC score	0.121761 (rank : 59)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	38	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX52_MOUSE
NC score	0.121759 (rank : 60)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	38	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_HUMAN
NC score	0.121556 (rank : 61)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	38	Target Neighborhood Hits	122	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX46_MOUSE
NC score	0.121455 (rank : 62)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	38	Target Neighborhood Hits	358	Shared Neighborhood Hits	27
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX56_MOUSE
NC score	0.121209 (rank : 63)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	38	Target Neighborhood Hits	87	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX10_MOUSE
NC score	0.118017 (rank : 64)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	38	Target Neighborhood Hits	233	Shared Neighborhood Hits	26
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_MOUSE
NC score	0.117988 (rank : 65)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX10_HUMAN
NC score	0.117709 (rank : 66)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	38	Target Neighborhood Hits	210	Shared Neighborhood Hits	26
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
NC score	0.117116 (rank : 67)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	38	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX51_MOUSE
NC score	0.116102 (rank : 68)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	38	Target Neighborhood Hits	130	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX31_HUMAN
NC score	0.115012 (rank : 69)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX51_HUMAN
NC score	0.109797 (rank : 70)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	38	Target Neighborhood Hits	332	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

BLM_MOUSE
NC score	0.066769 (rank : 71)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	108	Shared Neighborhood Hits	24
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ4_HUMAN
NC score	0.063571 (rank : 72)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	38	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

BLM_HUMAN
NC score	0.061270 (rank : 73)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ4_MOUSE
NC score	0.060852 (rank : 74)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	38	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

POP1_HUMAN
NC score	0.057276 (rank : 75)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q99575, Q15037	Gene names	POP1, KIAA0061
Domain Architecture
Description	Ribonucleases P/MRP protein subunit POP1 (EC 3.1.26.5) (hPOP1).

WRN_HUMAN
NC score	0.055196 (rank : 76)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	24
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.054387 (rank : 77)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	38	Target Neighborhood Hits	295	Shared Neighborhood Hits	24
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

FANCM_HUMAN
NC score	0.052541 (rank : 78)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	38	Target Neighborhood Hits	210	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

ATX1_MOUSE
NC score	0.050147 (rank : 79)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ATX1_HUMAN
NC score	0.047133 (rank : 80)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

SFRIP_HUMAN
NC score	0.039292 (rank : 81)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	530	Shared Neighborhood Hits	8
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SHD_HUMAN
NC score	0.020054 (rank : 82)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

ADDB_MOUSE
NC score	0.016214 (rank : 83)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	574	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ANKR6_HUMAN
NC score	0.014166 (rank : 84)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

T3JAM_HUMAN
NC score	0.013865 (rank : 85)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	533	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

WBS14_HUMAN
NC score	0.013292 (rank : 86)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	273	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

GRAP1_HUMAN
NC score	0.008909 (rank : 87)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	944	Shared Neighborhood Hits	5
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

NEB1_HUMAN
NC score	0.007707 (rank : 88)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	829	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).