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Network neighborhood for query Sequence : ATX1_HUMAN

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ATX1_HUMAN
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATX1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

ATX1_MOUSE
θ value	0 (rank : 2)	NC score	0.901839 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

HBP1_MOUSE
θ value	5.81887e-07 (rank : 3)	NC score	0.248580 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_HUMAN
θ value	2.88788e-06 (rank : 4)	NC score	0.238935 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

RERE_MOUSE
θ value	0.0431538 (rank : 5)	NC score	0.073052 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	785	Shared Neighborhood Hits	26
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NCOA6_MOUSE
θ value	0.0961366 (rank : 6)	NC score	0.097164 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	1076	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ERRFI_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.093937 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

NCOA6_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.084997 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	1202	Shared Neighborhood Hits	30
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NFAC2_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.039383 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

PDZD2_HUMAN
θ value	0.21417 (rank : 10)	NC score	0.037359 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	772	Shared Neighborhood Hits	22
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PPRB_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.096832 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

GMEB2_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.043044 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

MIRO2_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.030379 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IXI1, Q8NF53, Q96C13, Q96S17, Q9BT60, Q9H7M8	Gene names	RHOT2, ARHT2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (hMiro-2) (Ras homolog gene family member T2).

NUCB2_MOUSE
θ value	0.47712 (rank : 14)	NC score	0.033568 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	459	Shared Neighborhood Hits	7
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

RRP5_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.053130 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

UACA_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.011088 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	1620	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

DACH1_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.037765 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DOT1L_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.078001 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	660	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PPRB_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.083874 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	311	Shared Neighborhood Hits	15
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

MAK_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.008900 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	873	Shared Neighborhood Hits	11
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

PCNT_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.018327 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	1551	Shared Neighborhood Hits	21
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TCF20_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.038759 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ATX2L_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.050867 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	443	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

WASF1_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.045055 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WNK2_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.012646 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	1407	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZEP1_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.025182 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	1036	Shared Neighborhood Hits	16
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

CAC1I_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.018473 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	138	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CIC_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.060371 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	992	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ETV3_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.016246 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	312	Shared Neighborhood Hits	10
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

PIAS3_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.031651 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PTC2_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.020165 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

R3HD2_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.050690 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

SOX5_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.051689 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	219	Shared Neighborhood Hits	15
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.051658 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

STK10_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.008536 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	1921	Shared Neighborhood Hits	27
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ADIPO_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.025675 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	182	Shared Neighborhood Hits	10
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

CO3A1_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.026531 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	466	Shared Neighborhood Hits	18
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MTMRD_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.016267 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

RPTN_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.027098 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

ATX2L_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.047598 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	401	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CNTRB_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.015653 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	1029	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DNMBP_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.012397 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ERRFI_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.057445 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

HELZ_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.022531 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

M3K3_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.008010 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	885	Shared Neighborhood Hits	12
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

PGBM_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.003538 (rank : 82)
Query Neighborhood Hits	79	Target Neighborhood Hits	1073	Shared Neighborhood Hits	3
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PIAS3_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.030620 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PKHA4_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.034059 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	283	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RPTN_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.023159 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SSH1_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.012458 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

UPAR_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.025013 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q03405, Q12876, Q15845, Q16887, Q9NYC8, Q9UD69, Q9UEA6, Q9UM92, Q9UMV0	Gene names	PLAUR, MO3, UPAR
Domain Architecture
Description	Urokinase plasminogen activator surface receptor precursor (uPAR) (U- PAR) (Monocyte activation antigen Mo3) (CD87 antigen).

WASF1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.042851 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CC026_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.047133 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

EVI2B_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.027227 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

FILA_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.043169 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	685	Shared Neighborhood Hits	17
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MKL1_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.017373 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

RHG25_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.018129 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	550	Shared Neighborhood Hits	14
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TAF4_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.030389 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	687	Shared Neighborhood Hits	22
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TLK1_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.006157 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	967	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TOP1_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.033039 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ADIPO_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.012232 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

M3K3_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.005659 (rank : 80)
Query Neighborhood Hits	79	Target Neighborhood Hits	876	Shared Neighborhood Hits	9
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MLL3_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.021821 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PRD14_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.000528 (rank : 83)
Query Neighborhood Hits	79	Target Neighborhood Hits	757	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

RELB_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.011024 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

STK10_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.008111 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	2132	Shared Neighborhood Hits	30
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BCL9_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.035181 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	1008	Shared Neighborhood Hits	31
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CNOT3_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.023150 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

COKA1_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.008874 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CP250_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.007621 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	1805	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CUTL2_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.010669 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	906	Shared Neighborhood Hits	18
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MLL3_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.021493 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	1644	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NOLC1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.030104 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	452	Shared Neighborhood Hits	15
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PTN23_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.027485 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	726	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RXRA_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.003573 (rank : 81)
Query Neighborhood Hits	79	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

SFRP1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.020301 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP1_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.020373 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SRRM2_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.042808 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	1470	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZN509_MOUSE
θ value	8.99809 (rank : 79)	NC score	-0.000208 (rank : 84)
Query Neighborhood Hits	79	Target Neighborhood Hits	990	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ATN1_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.086946 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MBD6_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.062365 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	349	Shared Neighborhood Hits	14
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

RBM16_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.065753 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	300	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RERE_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.052119 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	779	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

WIRE_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.051563 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	329	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

Hits sorted by NC score

ATX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

ATX1_MOUSE
NC score	0.901839 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

HBP1_MOUSE
NC score	0.248580 (rank : 3)	θ value	5.81887e-07 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_HUMAN
NC score	0.238935 (rank : 4)	θ value	2.88788e-06 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

NCOA6_MOUSE
NC score	0.097164 (rank : 5)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	1076	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PPRB_MOUSE
NC score	0.096832 (rank : 6)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

ERRFI_HUMAN
NC score	0.093937 (rank : 7)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

ATN1_HUMAN
NC score	0.086946 (rank : 8)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	79	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NCOA6_HUMAN
NC score	0.084997 (rank : 9)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	1202	Shared Neighborhood Hits	30
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PPRB_HUMAN
NC score	0.083874 (rank : 10)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	311	Shared Neighborhood Hits	15
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

DOT1L_HUMAN
NC score	0.078001 (rank : 11)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	660	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

RERE_MOUSE
NC score	0.073052 (rank : 12)	θ value	0.0431538 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	785	Shared Neighborhood Hits	26
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RBM16_HUMAN
NC score	0.065753 (rank : 13)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	79	Target Neighborhood Hits	300	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

MBD6_HUMAN
NC score	0.062365 (rank : 14)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	79	Target Neighborhood Hits	349	Shared Neighborhood Hits	14
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CIC_HUMAN
NC score	0.060371 (rank : 15)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	992	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ERRFI_MOUSE
NC score	0.057445 (rank : 16)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

RRP5_HUMAN
NC score	0.053130 (rank : 17)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

RERE_HUMAN
NC score	0.052119 (rank : 18)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	79	Target Neighborhood Hits	779	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SOX5_HUMAN
NC score	0.051689 (rank : 19)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	219	Shared Neighborhood Hits	15
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
NC score	0.051658 (rank : 20)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

WIRE_HUMAN
NC score	0.051563 (rank : 21)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	79	Target Neighborhood Hits	329	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ATX2L_HUMAN
NC score	0.050867 (rank : 22)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	443	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

R3HD2_MOUSE
NC score	0.050690 (rank : 23)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

ATX2L_MOUSE
NC score	0.047598 (rank : 24)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	401	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CC026_MOUSE
NC score	0.047133 (rank : 25)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

WASF1_MOUSE
NC score	0.045055 (rank : 26)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

FILA_HUMAN
NC score	0.043169 (rank : 27)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	685	Shared Neighborhood Hits	17
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GMEB2_HUMAN
NC score	0.043044 (rank : 28)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

WASF1_HUMAN
NC score	0.042851 (rank : 29)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

SRRM2_MOUSE
NC score	0.042808 (rank : 30)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	1470	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFAC2_HUMAN
NC score	0.039383 (rank : 31)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

TCF20_MOUSE
NC score	0.038759 (rank : 32)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

DACH1_MOUSE
NC score	0.037765 (rank : 33)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

PDZD2_HUMAN
NC score	0.037359 (rank : 34)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	772	Shared Neighborhood Hits	22
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

BCL9_HUMAN
NC score	0.035181 (rank : 35)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	1008	Shared Neighborhood Hits	31
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PKHA4_HUMAN
NC score	0.034059 (rank : 36)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	283	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

NUCB2_MOUSE
NC score	0.033568 (rank : 37)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	459	Shared Neighborhood Hits	7
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

TOP1_MOUSE
NC score	0.033039 (rank : 38)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

PIAS3_HUMAN
NC score	0.031651 (rank : 39)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
NC score	0.030620 (rank : 40)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

TAF4_HUMAN
NC score	0.030389 (rank : 41)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	687	Shared Neighborhood Hits	22
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MIRO2_HUMAN
NC score	0.030379 (rank : 42)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IXI1, Q8NF53, Q96C13, Q96S17, Q9BT60, Q9H7M8	Gene names	RHOT2, ARHT2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (hMiro-2) (Ras homolog gene family member T2).

NOLC1_HUMAN
NC score	0.030104 (rank : 43)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	452	Shared Neighborhood Hits	15
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PTN23_MOUSE
NC score	0.027485 (rank : 44)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	726	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

EVI2B_HUMAN
NC score	0.027227 (rank : 45)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

RPTN_HUMAN
NC score	0.027098 (rank : 46)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

CO3A1_MOUSE
NC score	0.026531 (rank : 47)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	466	Shared Neighborhood Hits	18
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ADIPO_MOUSE
NC score	0.025675 (rank : 48)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	182	Shared Neighborhood Hits	10
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

ZEP1_HUMAN
NC score	0.025182 (rank : 49)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	1036	Shared Neighborhood Hits	16
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

UPAR_HUMAN
NC score	0.025013 (rank : 50)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q03405, Q12876, Q15845, Q16887, Q9NYC8, Q9UD69, Q9UEA6, Q9UM92, Q9UMV0	Gene names	PLAUR, MO3, UPAR
Domain Architecture
Description	Urokinase plasminogen activator surface receptor precursor (uPAR) (U- PAR) (Monocyte activation antigen Mo3) (CD87 antigen).

RPTN_MOUSE
NC score	0.023159 (rank : 51)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CNOT3_HUMAN
NC score	0.023150 (rank : 52)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

HELZ_HUMAN
NC score	0.022531 (rank : 53)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

MLL3_MOUSE
NC score	0.021821 (rank : 54)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.021493 (rank : 55)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	1644	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SFRP1_MOUSE
NC score	0.020373 (rank : 56)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP1_HUMAN
NC score	0.020301 (rank : 57)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

PTC2_HUMAN
NC score	0.020165 (rank : 58)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

CAC1I_HUMAN
NC score	0.018473 (rank : 59)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	138	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

PCNT_HUMAN
NC score	0.018327 (rank : 60)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	1551	Shared Neighborhood Hits	21
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RHG25_HUMAN
NC score	0.018129 (rank : 61)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	550	Shared Neighborhood Hits	14
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MKL1_HUMAN
NC score	0.017373 (rank : 62)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MTMRD_HUMAN
NC score	0.016267 (rank : 63)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

ETV3_HUMAN
NC score	0.016246 (rank : 64)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	312	Shared Neighborhood Hits	10
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

CNTRB_MOUSE
NC score	0.015653 (rank : 65)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	1029	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

WNK2_HUMAN
NC score	0.012646 (rank : 66)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	1407	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SSH1_MOUSE
NC score	0.012458 (rank : 67)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

DNMBP_MOUSE
NC score	0.012397 (rank : 68)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ADIPO_HUMAN
NC score	0.012232 (rank : 69)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

UACA_MOUSE
NC score	0.011088 (rank : 70)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	1620	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

RELB_MOUSE
NC score	0.011024 (rank : 71)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

CUTL2_HUMAN
NC score	0.010669 (rank : 72)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	906	Shared Neighborhood Hits	18
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MAK_MOUSE
NC score	0.008900 (rank : 73)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	873	Shared Neighborhood Hits	11
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

COKA1_HUMAN
NC score	0.008874 (rank : 74)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

STK10_HUMAN
NC score	0.008536 (rank : 75)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	1921	Shared Neighborhood Hits	27
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
NC score	0.008111 (rank : 76)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	2132	Shared Neighborhood Hits	30
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

M3K3_HUMAN
NC score	0.008010 (rank : 77)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	885	Shared Neighborhood Hits	12
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

CP250_HUMAN
NC score	0.007621 (rank : 78)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	1805	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

TLK1_HUMAN
NC score	0.006157 (rank : 79)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	967	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

M3K3_MOUSE
NC score	0.005659 (rank : 80)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	876	Shared Neighborhood Hits	9
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

RXRA_HUMAN
NC score	0.003573 (rank : 81)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

PGBM_MOUSE
NC score	0.003538 (rank : 82)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	1073	Shared Neighborhood Hits	3
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PRD14_HUMAN
NC score	0.000528 (rank : 83)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	757	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

ZN509_MOUSE
NC score	-0.000208 (rank : 84)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	990	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.