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Network neighborhood for query Sequence : PKHA4_HUMAN

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PKHA4_HUMAN
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PKHA4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	283	Target Neighborhood Hits	283	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	0 (rank : 2)	NC score	0.948125 (rank : 2)
Query Neighborhood Hits	283	Target Neighborhood Hits	202	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	4.27553e-34 (rank : 3)	NC score	0.641537 (rank : 5)
Query Neighborhood Hits	283	Target Neighborhood Hits	455	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	6.17384e-33 (rank : 4)	NC score	0.695918 (rank : 3)
Query Neighborhood Hits	283	Target Neighborhood Hits	556	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	2.34606e-32 (rank : 5)	NC score	0.690181 (rank : 4)
Query Neighborhood Hits	283	Target Neighborhood Hits	591	Shared Neighborhood Hits	134
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CNKR1_HUMAN
θ value	3.29651e-10 (rank : 6)	NC score	0.510786 (rank : 6)
Query Neighborhood Hits	283	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	2.61198e-07 (rank : 7)	NC score	0.422019 (rank : 8)
Query Neighborhood Hits	283	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	2.61198e-07 (rank : 8)	NC score	0.422472 (rank : 7)
Query Neighborhood Hits	283	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

RHG25_HUMAN
θ value	5.81887e-07 (rank : 9)	NC score	0.277833 (rank : 24)
Query Neighborhood Hits	283	Target Neighborhood Hits	550	Shared Neighborhood Hits	105
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	7.59969e-07 (rank : 10)	NC score	0.278579 (rank : 23)
Query Neighborhood Hits	283	Target Neighborhood Hits	492	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CYH2_HUMAN
θ value	1.87187e-05 (rank : 11)	NC score	0.324347 (rank : 12)
Query Neighborhood Hits	283	Target Neighborhood Hits	175	Shared Neighborhood Hits	76
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	1.87187e-05 (rank : 12)	NC score	0.324104 (rank : 13)
Query Neighborhood Hits	283	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH1_HUMAN
θ value	4.1701e-05 (rank : 13)	NC score	0.328067 (rank : 10)
Query Neighborhood Hits	283	Target Neighborhood Hits	184	Shared Neighborhood Hits	79
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	4.1701e-05 (rank : 14)	NC score	0.327286 (rank : 11)
Query Neighborhood Hits	283	Target Neighborhood Hits	176	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
θ value	4.1701e-05 (rank : 15)	NC score	0.328942 (rank : 9)
Query Neighborhood Hits	283	Target Neighborhood Hits	137	Shared Neighborhood Hits	70
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

MYO10_HUMAN
θ value	0.000158464 (rank : 16)	NC score	0.120833 (rank : 76)
Query Neighborhood Hits	283	Target Neighborhood Hits	920	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MRIP_MOUSE
θ value	0.000270298 (rank : 17)	NC score	0.240784 (rank : 26)
Query Neighborhood Hits	283	Target Neighborhood Hits	569	Shared Neighborhood Hits	101
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

CENB2_HUMAN
θ value	0.000602161 (rank : 18)	NC score	0.180474 (rank : 40)
Query Neighborhood Hits	283	Target Neighborhood Hits	425	Shared Neighborhood Hits	63
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

3BP2_HUMAN
θ value	0.000786445 (rank : 19)	NC score	0.311410 (rank : 18)
Query Neighborhood Hits	283	Target Neighborhood Hits	296	Shared Neighborhood Hits	69
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CYH3_MOUSE
θ value	0.000786445 (rank : 20)	NC score	0.319205 (rank : 15)
Query Neighborhood Hits	283	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
θ value	0.00134147 (rank : 21)	NC score	0.315710 (rank : 16)
Query Neighborhood Hits	283	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

PTPR2_MOUSE
θ value	0.00134147 (rank : 22)	NC score	0.034378 (rank : 362)
Query Neighborhood Hits	283	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

FARP2_HUMAN
θ value	0.00228821 (rank : 23)	NC score	0.159877 (rank : 50)
Query Neighborhood Hits	283	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

OSBP1_HUMAN
θ value	0.00228821 (rank : 24)	NC score	0.156638 (rank : 52)
Query Neighborhood Hits	283	Target Neighborhood Hits	180	Shared Neighborhood Hits	51
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CENB1_HUMAN
θ value	0.00298849 (rank : 25)	NC score	0.165800 (rank : 45)
Query Neighborhood Hits	283	Target Neighborhood Hits	383	Shared Neighborhood Hits	67
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CYH4_MOUSE
θ value	0.00298849 (rank : 26)	NC score	0.312497 (rank : 17)
Query Neighborhood Hits	283	Target Neighborhood Hits	134	Shared Neighborhood Hits	67
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

FGD5_MOUSE
θ value	0.00298849 (rank : 27)	NC score	0.199142 (rank : 34)
Query Neighborhood Hits	283	Target Neighborhood Hits	170	Shared Neighborhood Hits	42
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

3BP2_MOUSE
θ value	0.00390308 (rank : 28)	NC score	0.303610 (rank : 19)
Query Neighborhood Hits	283	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

FARP2_MOUSE
θ value	0.00390308 (rank : 29)	NC score	0.162790 (rank : 46)
Query Neighborhood Hits	283	Target Neighborhood Hits	209	Shared Neighborhood Hits	54
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD5_HUMAN
θ value	0.00390308 (rank : 30)	NC score	0.195380 (rank : 35)
Query Neighborhood Hits	283	Target Neighborhood Hits	235	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

PKHA1_HUMAN
θ value	0.00390308 (rank : 31)	NC score	0.319630 (rank : 14)
Query Neighborhood Hits	283	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

FGD1_MOUSE
θ value	0.00665767 (rank : 32)	NC score	0.161020 (rank : 48)
Query Neighborhood Hits	283	Target Neighborhood Hits	387	Shared Neighborhood Hits	72
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ANLN_HUMAN
θ value	0.00869519 (rank : 33)	NC score	0.223233 (rank : 30)
Query Neighborhood Hits	283	Target Neighborhood Hits	222	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DGKH_HUMAN
θ value	0.00869519 (rank : 34)	NC score	0.156176 (rank : 53)
Query Neighborhood Hits	283	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

MRIP_HUMAN
θ value	0.00869519 (rank : 35)	NC score	0.224728 (rank : 29)
Query Neighborhood Hits	283	Target Neighborhood Hits	578	Shared Neighborhood Hits	99
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

TARA_MOUSE
θ value	0.0113563 (rank : 36)	NC score	0.206149 (rank : 33)
Query Neighborhood Hits	283	Target Neighborhood Hits	1133	Shared Neighborhood Hits	142
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ANLN_MOUSE
θ value	0.0193708 (rank : 37)	NC score	0.192233 (rank : 36)
Query Neighborhood Hits	283	Target Neighborhood Hits	297	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

FGD1_HUMAN
θ value	0.0193708 (rank : 38)	NC score	0.160238 (rank : 49)
Query Neighborhood Hits	283	Target Neighborhood Hits	367	Shared Neighborhood Hits	75
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

OGFR_HUMAN
θ value	0.0193708 (rank : 39)	NC score	0.095291 (rank : 119)
Query Neighborhood Hits	283	Target Neighborhood Hits	1582	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CENB5_HUMAN
θ value	0.0252991 (rank : 40)	NC score	0.170370 (rank : 43)
Query Neighborhood Hits	283	Target Neighborhood Hits	395	Shared Neighborhood Hits	65
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

GNRP_MOUSE
θ value	0.0252991 (rank : 41)	NC score	0.149422 (rank : 57)
Query Neighborhood Hits	283	Target Neighborhood Hits	191	Shared Neighborhood Hits	51
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

RIMB1_MOUSE
θ value	0.0252991 (rank : 42)	NC score	0.079672 (rank : 149)
Query Neighborhood Hits	283	Target Neighborhood Hits	1376	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ALEX_HUMAN
θ value	0.0330416 (rank : 43)	NC score	0.116006 (rank : 83)
Query Neighborhood Hits	283	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANR15_HUMAN
θ value	0.0431538 (rank : 44)	NC score	0.047182 (rank : 331)
Query Neighborhood Hits	283	Target Neighborhood Hits	478	Shared Neighborhood Hits	35
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

CENA1_HUMAN
θ value	0.0431538 (rank : 45)	NC score	0.155533 (rank : 55)
Query Neighborhood Hits	283	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CEND2_HUMAN
θ value	0.0431538 (rank : 46)	NC score	0.155792 (rank : 54)
Query Neighborhood Hits	283	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CRSP7_HUMAN
θ value	0.0431538 (rank : 47)	NC score	0.076552 (rank : 159)
Query Neighborhood Hits	283	Target Neighborhood Hits	247	Shared Neighborhood Hits	21
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

FGD6_MOUSE
θ value	0.0431538 (rank : 48)	NC score	0.176357 (rank : 41)
Query Neighborhood Hits	283	Target Neighborhood Hits	282	Shared Neighborhood Hits	61
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

IASPP_MOUSE
θ value	0.0431538 (rank : 49)	NC score	0.083272 (rank : 141)
Query Neighborhood Hits	283	Target Neighborhood Hits	1024	Shared Neighborhood Hits	89
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RIMB1_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.093486 (rank : 123)
Query Neighborhood Hits	283	Target Neighborhood Hits	1479	Shared Neighborhood Hits	102
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SI1L3_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.056296 (rank : 252)
Query Neighborhood Hits	283	Target Neighborhood Hits	305	Shared Neighborhood Hits	40
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

DOCK9_MOUSE
θ value	0.0563607 (rank : 52)	NC score	0.104065 (rank : 97)
Query Neighborhood Hits	283	Target Neighborhood Hits	79	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

PKHA2_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.285305 (rank : 22)
Query Neighborhood Hits	283	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHB2_MOUSE
θ value	0.0736092 (rank : 54)	NC score	0.255777 (rank : 25)
Query Neighborhood Hits	283	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

TARA_HUMAN
θ value	0.0736092 (rank : 55)	NC score	0.174339 (rank : 42)
Query Neighborhood Hits	283	Target Neighborhood Hits	1626	Shared Neighborhood Hits	167
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CEND1_HUMAN
θ value	0.0961366 (rank : 56)	NC score	0.155245 (rank : 56)
Query Neighborhood Hits	283	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

NPBL_MOUSE
θ value	0.0961366 (rank : 57)	NC score	0.085911 (rank : 139)
Query Neighborhood Hits	283	Target Neighborhood Hits	1041	Shared Neighborhood Hits	68
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

OSBP2_MOUSE
θ value	0.0961366 (rank : 58)	NC score	0.116601 (rank : 82)
Query Neighborhood Hits	283	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PCLO_MOUSE
θ value	0.0961366 (rank : 59)	NC score	0.089682 (rank : 127)
Query Neighborhood Hits	283	Target Neighborhood Hits	2275	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PHLB1_HUMAN
θ value	0.0961366 (rank : 60)	NC score	0.140879 (rank : 64)
Query Neighborhood Hits	283	Target Neighborhood Hits	1038	Shared Neighborhood Hits	119
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA2_MOUSE
θ value	0.0961366 (rank : 61)	NC score	0.294095 (rank : 21)
Query Neighborhood Hits	283	Target Neighborhood Hits	116	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHB1_HUMAN
θ value	0.0961366 (rank : 62)	NC score	0.235535 (rank : 28)
Query Neighborhood Hits	283	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

SAPS1_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.065060 (rank : 203)
Query Neighborhood Hits	283	Target Neighborhood Hits	704	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TRAIP_MOUSE
θ value	0.0961366 (rank : 64)	NC score	0.053518 (rank : 269)
Query Neighborhood Hits	283	Target Neighborhood Hits	745	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

FARP1_HUMAN
θ value	0.125558 (rank : 65)	NC score	0.156896 (rank : 51)
Query Neighborhood Hits	283	Target Neighborhood Hits	241	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

GNRP_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.148804 (rank : 59)
Query Neighborhood Hits	283	Target Neighborhood Hits	239	Shared Neighborhood Hits	56
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

K2C1B_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.034666 (rank : 360)
Query Neighborhood Hits	283	Target Neighborhood Hits	542	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

LRC56_HUMAN
θ value	0.125558 (rank : 68)	NC score	0.060968 (rank : 226)
Query Neighborhood Hits	283	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MAGE1_HUMAN
θ value	0.125558 (rank : 69)	NC score	0.062834 (rank : 215)
Query Neighborhood Hits	283	Target Neighborhood Hits	1389	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DOCK9_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.102197 (rank : 103)
Query Neighborhood Hits	283	Target Neighborhood Hits	82	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

FA47A_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.088986 (rank : 131)
Query Neighborhood Hits	283	Target Neighborhood Hits	451	Shared Neighborhood Hits	52
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

JPH2_HUMAN
θ value	0.163984 (rank : 72)	NC score	0.047307 (rank : 330)
Query Neighborhood Hits	283	Target Neighborhood Hits	639	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PKHB1_MOUSE
θ value	0.163984 (rank : 73)	NC score	0.217263 (rank : 31)
Query Neighborhood Hits	283	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

ZDHC5_MOUSE
θ value	0.163984 (rank : 74)	NC score	0.027148 (rank : 389)
Query Neighborhood Hits	283	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

CTRO_MOUSE
θ value	0.21417 (rank : 75)	NC score	0.031310 (rank : 375)
Query Neighborhood Hits	283	Target Neighborhood Hits	2344	Shared Neighborhood Hits	97
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GLI2_HUMAN
θ value	0.21417 (rank : 76)	NC score	0.007401 (rank : 431)
Query Neighborhood Hits	283	Target Neighborhood Hits	971	Shared Neighborhood Hits	37
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NIPBL_HUMAN
θ value	0.21417 (rank : 77)	NC score	0.069474 (rank : 178)
Query Neighborhood Hits	283	Target Neighborhood Hits	1311	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

KRHB6_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.029827 (rank : 381)
Query Neighborhood Hits	283	Target Neighborhood Hits	413	Shared Neighborhood Hits	35
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

LIPA1_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.051085 (rank : 303)
Query Neighborhood Hits	283	Target Neighborhood Hits	1294	Shared Neighborhood Hits	68
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MTMRD_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.093570 (rank : 122)
Query Neighborhood Hits	283	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

MYO15_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.044058 (rank : 340)
Query Neighborhood Hits	283	Target Neighborhood Hits	671	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_HUMAN
θ value	0.279714 (rank : 82)	NC score	0.096769 (rank : 114)
Query Neighborhood Hits	283	Target Neighborhood Hits	1202	Shared Neighborhood Hits	112
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OSBP2_HUMAN
θ value	0.279714 (rank : 83)	NC score	0.125267 (rank : 71)
Query Neighborhood Hits	283	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

PCDA2_HUMAN
θ value	0.279714 (rank : 84)	NC score	0.010664 (rank : 427)
Query Neighborhood Hits	283	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

BAZ2A_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.059296 (rank : 232)
Query Neighborhood Hits	283	Target Neighborhood Hits	744	Shared Neighborhood Hits	66
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CENA2_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.124915 (rank : 72)
Query Neighborhood Hits	283	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CEND1_MOUSE
θ value	0.365318 (rank : 87)	NC score	0.128178 (rank : 70)
Query Neighborhood Hits	283	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

K1C16_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.038538 (rank : 351)
Query Neighborhood Hits	283	Target Neighborhood Hits	440	Shared Neighborhood Hits	48
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

PKHA1_MOUSE
θ value	0.365318 (rank : 89)	NC score	0.300563 (rank : 20)
Query Neighborhood Hits	283	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHB2_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.240620 (rank : 27)
Query Neighborhood Hits	283	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

RGS3_MOUSE
θ value	0.365318 (rank : 91)	NC score	0.072787 (rank : 167)
Query Neighborhood Hits	283	Target Neighborhood Hits	1621	Shared Neighborhood Hits	123
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZN414_HUMAN
θ value	0.365318 (rank : 92)	NC score	0.046624 (rank : 332)
Query Neighborhood Hits	283	Target Neighborhood Hits	548	Shared Neighborhood Hits	38
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ZN575_HUMAN
θ value	0.365318 (rank : 93)	NC score	0.001231 (rank : 438)
Query Neighborhood Hits	283	Target Neighborhood Hits	739	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ANK2_HUMAN
θ value	0.47712 (rank : 94)	NC score	0.054072 (rank : 263)
Query Neighborhood Hits	283	Target Neighborhood Hits	1615	Shared Neighborhood Hits	117
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BSN_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.102348 (rank : 101)
Query Neighborhood Hits	283	Target Neighborhood Hits	2057	Shared Neighborhood Hits	155
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DIDO1_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.089902 (rank : 126)
Query Neighborhood Hits	283	Target Neighborhood Hits	960	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GAB2_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.148895 (rank : 58)
Query Neighborhood Hits	283	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

INVS_HUMAN
θ value	0.47712 (rank : 98)	NC score	0.028534 (rank : 384)
Query Neighborhood Hits	283	Target Neighborhood Hits	455	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

LSR_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.045004 (rank : 337)
Query Neighborhood Hits	283	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

PRGC2_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.054427 (rank : 260)
Query Neighborhood Hits	283	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

SC24C_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.064518 (rank : 205)
Query Neighborhood Hits	283	Target Neighborhood Hits	662	Shared Neighborhood Hits	59
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CO039_MOUSE
θ value	0.62314 (rank : 102)	NC score	0.067933 (rank : 187)
Query Neighborhood Hits	283	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CTRO_HUMAN
θ value	0.62314 (rank : 103)	NC score	0.029211 (rank : 383)
Query Neighborhood Hits	283	Target Neighborhood Hits	2092	Shared Neighborhood Hits	91
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CYTSA_HUMAN
θ value	0.62314 (rank : 104)	NC score	0.045041 (rank : 336)
Query Neighborhood Hits	283	Target Neighborhood Hits	1138	Shared Neighborhood Hits	77
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DGKD_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.093773 (rank : 121)
Query Neighborhood Hits	283	Target Neighborhood Hits	231	Shared Neighborhood Hits	32
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

FA47B_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.107752 (rank : 91)
Query Neighborhood Hits	283	Target Neighborhood Hits	431	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FGD6_HUMAN
θ value	0.62314 (rank : 107)	NC score	0.161212 (rank : 47)
Query Neighborhood Hits	283	Target Neighborhood Hits	237	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

IASPP_HUMAN
θ value	0.62314 (rank : 108)	NC score	0.072166 (rank : 169)
Query Neighborhood Hits	283	Target Neighborhood Hits	688	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K1802_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.066341 (rank : 193)
Query Neighborhood Hits	283	Target Neighborhood Hits	1596	Shared Neighborhood Hits	109
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MBB1A_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.071346 (rank : 171)
Query Neighborhood Hits	283	Target Neighborhood Hits	665	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NIN_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.050734 (rank : 311)
Query Neighborhood Hits	283	Target Neighborhood Hits	1416	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CAPS1_HUMAN
θ value	0.813845 (rank : 112)	NC score	0.081930 (rank : 146)
Query Neighborhood Hits	283	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
θ value	0.813845 (rank : 113)	NC score	0.082335 (rank : 144)
Query Neighborhood Hits	283	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CK024_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.075215 (rank : 162)
Query Neighborhood Hits	283	Target Neighborhood Hits	408	Shared Neighborhood Hits	56
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CROCC_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.066877 (rank : 192)
Query Neighborhood Hits	283	Target Neighborhood Hits	1409	Shared Neighborhood Hits	86
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA4_MOUSE
θ value	0.813845 (rank : 116)	NC score	0.051331 (rank : 296)
Query Neighborhood Hits	283	Target Neighborhood Hits	1939	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SRRM1_MOUSE
θ value	0.813845 (rank : 117)	NC score	0.131358 (rank : 67)
Query Neighborhood Hits	283	Target Neighborhood Hits	966	Shared Neighborhood Hits	113
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

UBP42_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.032214 (rank : 372)
Query Neighborhood Hits	283	Target Neighborhood Hits	445	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

WBS14_MOUSE
θ value	0.813845 (rank : 119)	NC score	0.057520 (rank : 245)
Query Neighborhood Hits	283	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

BAZ2A_HUMAN
θ value	1.06291 (rank : 120)	NC score	0.052188 (rank : 280)
Query Neighborhood Hits	283	Target Neighborhood Hits	780	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CHD9_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.022674 (rank : 395)
Query Neighborhood Hits	283	Target Neighborhood Hits	343	Shared Neighborhood Hits	19
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	1.06291 (rank : 122)	NC score	0.022270 (rank : 398)
Query Neighborhood Hits	283	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

MAST4_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.017654 (rank : 415)
Query Neighborhood Hits	283	Target Neighborhood Hits	1804	Shared Neighborhood Hits	101
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MK15_MOUSE
θ value	1.06291 (rank : 124)	NC score	0.002024 (rank : 435)
Query Neighborhood Hits	283	Target Neighborhood Hits	843	Shared Neighborhood Hits	20
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

NCOA6_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.078274 (rank : 154)
Query Neighborhood Hits	283	Target Neighborhood Hits	1076	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PCLO_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.103380 (rank : 99)
Query Neighborhood Hits	283	Target Neighborhood Hits	2046	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRRT3_HUMAN
θ value	1.06291 (rank : 127)	NC score	0.089180 (rank : 130)
Query Neighborhood Hits	283	Target Neighborhood Hits	998	Shared Neighborhood Hits	95
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SIA7A_HUMAN
θ value	1.06291 (rank : 128)	NC score	0.025782 (rank : 392)
Query Neighborhood Hits	283	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SPTN2_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.041387 (rank : 346)
Query Neighborhood Hits	283	Target Neighborhood Hits	535	Shared Neighborhood Hits	60
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SRRM1_HUMAN
θ value	1.06291 (rank : 130)	NC score	0.138118 (rank : 65)
Query Neighborhood Hits	283	Target Neighborhood Hits	690	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SYNJ1_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.065777 (rank : 197)
Query Neighborhood Hits	283	Target Neighborhood Hits	498	Shared Neighborhood Hits	85
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TCGAP_HUMAN
θ value	1.06291 (rank : 132)	NC score	0.062492 (rank : 217)
Query Neighborhood Hits	283	Target Neighborhood Hits	872	Shared Neighborhood Hits	79
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CT128_HUMAN
θ value	1.38821 (rank : 133)	NC score	0.034880 (rank : 358)
Query Neighborhood Hits	283	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

DNMBP_HUMAN
θ value	1.38821 (rank : 134)	NC score	0.042549 (rank : 343)
Query Neighborhood Hits	283	Target Neighborhood Hits	413	Shared Neighborhood Hits	30
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DYN2_HUMAN
θ value	1.38821 (rank : 135)	NC score	0.104386 (rank : 96)
Query Neighborhood Hits	283	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
θ value	1.38821 (rank : 136)	NC score	0.102321 (rank : 102)
Query Neighborhood Hits	283	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

GAB2_MOUSE
θ value	1.38821 (rank : 137)	NC score	0.146778 (rank : 61)
Query Neighborhood Hits	283	Target Neighborhood Hits	220	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GOGA5_MOUSE
θ value	1.38821 (rank : 138)	NC score	0.066255 (rank : 195)
Query Neighborhood Hits	283	Target Neighborhood Hits	1434	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

HCLS1_MOUSE
θ value	1.38821 (rank : 139)	NC score	0.027525 (rank : 387)
Query Neighborhood Hits	283	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

K1802_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.055840 (rank : 254)
Query Neighborhood Hits	283	Target Neighborhood Hits	1378	Shared Neighborhood Hits	102
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NFH_MOUSE
θ value	1.38821 (rank : 141)	NC score	0.080742 (rank : 147)
Query Neighborhood Hits	283	Target Neighborhood Hits	2247	Shared Neighborhood Hits	154
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RP3A_MOUSE
θ value	1.38821 (rank : 142)	NC score	0.032908 (rank : 367)
Query Neighborhood Hits	283	Target Neighborhood Hits	510	Shared Neighborhood Hits	57
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SESN2_HUMAN
θ value	1.38821 (rank : 143)	NC score	0.019313 (rank : 410)
Query Neighborhood Hits	283	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

SGIP1_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.068846 (rank : 181)
Query Neighborhood Hits	283	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SOX13_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.031131 (rank : 376)
Query Neighborhood Hits	283	Target Neighborhood Hits	464	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

TPR_HUMAN
θ value	1.38821 (rank : 146)	NC score	0.055221 (rank : 258)
Query Neighborhood Hits	283	Target Neighborhood Hits	1921	Shared Neighborhood Hits	89
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

BAT3_HUMAN
θ value	1.81305 (rank : 147)	NC score	0.060579 (rank : 227)
Query Neighborhood Hits	283	Target Neighborhood Hits	490	Shared Neighborhood Hits	54
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	1.81305 (rank : 148)	NC score	0.068226 (rank : 186)
Query Neighborhood Hits	283	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CD2_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.051158 (rank : 301)
Query Neighborhood Hits	283	Target Neighborhood Hits	504	Shared Neighborhood Hits	52
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CT151_HUMAN
θ value	1.81305 (rank : 150)	NC score	0.091228 (rank : 124)
Query Neighborhood Hits	283	Target Neighborhood Hits	382	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

K1C12_MOUSE
θ value	1.81305 (rank : 151)	NC score	0.029609 (rank : 382)
Query Neighborhood Hits	283	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

KCNQ4_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.015508 (rank : 420)
Query Neighborhood Hits	283	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

NOS3_MOUSE
θ value	1.81305 (rank : 153)	NC score	0.015467 (rank : 421)
Query Neighborhood Hits	283	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

PHLB1_MOUSE
θ value	1.81305 (rank : 154)	NC score	0.140932 (rank : 63)
Query Neighborhood Hits	283	Target Neighborhood Hits	678	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SART3_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.021560 (rank : 404)
Query Neighborhood Hits	283	Target Neighborhood Hits	301	Shared Neighborhood Hits	9
SwissProt Accessions	Q15020, Q58F06, Q8IUS1, Q96J95	Gene names	SART3, KIAA0156, TIP110
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (hSART-3) (Tat-interacting protein of 110 kDa) (Tip110).

SPEG_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.017990 (rank : 414)
Query Neighborhood Hits	283	Target Neighborhood Hits	1762	Shared Neighborhood Hits	104
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRAIP_HUMAN
θ value	1.81305 (rank : 157)	NC score	0.052720 (rank : 274)
Query Neighborhood Hits	283	Target Neighborhood Hits	780	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

CBP_MOUSE
θ value	2.36792 (rank : 158)	NC score	0.058284 (rank : 241)
Query Neighborhood Hits	283	Target Neighborhood Hits	1051	Shared Neighborhood Hits	90
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CK037_HUMAN
θ value	2.36792 (rank : 159)	NC score	0.048120 (rank : 327)
Query Neighborhood Hits	283	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N53	Gene names	C11orf37
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C11orf37.

CP250_MOUSE
θ value	2.36792 (rank : 160)	NC score	0.056575 (rank : 250)
Query Neighborhood Hits	283	Target Neighborhood Hits	1583	Shared Neighborhood Hits	82
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DOK7_MOUSE
θ value	2.36792 (rank : 161)	NC score	0.035118 (rank : 357)
Query Neighborhood Hits	283	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DYN3_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.096481 (rank : 115)
Query Neighborhood Hits	283	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

GRIP2_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.024236 (rank : 393)
Query Neighborhood Hits	283	Target Neighborhood Hits	256	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

JADE2_MOUSE
θ value	2.36792 (rank : 164)	NC score	0.038919 (rank : 350)
Query Neighborhood Hits	283	Target Neighborhood Hits	560	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MILK1_MOUSE
θ value	2.36792 (rank : 165)	NC score	0.059064 (rank : 235)
Query Neighborhood Hits	283	Target Neighborhood Hits	788	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLL3_MOUSE
θ value	2.36792 (rank : 166)	NC score	0.058957 (rank : 238)
Query Neighborhood Hits	283	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PERI_MOUSE
θ value	2.36792 (rank : 167)	NC score	0.034062 (rank : 363)
Query Neighborhood Hits	283	Target Neighborhood Hits	502	Shared Neighborhood Hits	44
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

RGS3_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.044821 (rank : 338)
Query Neighborhood Hits	283	Target Neighborhood Hits	1375	Shared Neighborhood Hits	95
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TARSH_HUMAN
θ value	2.36792 (rank : 169)	NC score	0.078725 (rank : 153)
Query Neighborhood Hits	283	Target Neighborhood Hits	768	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

WASL_MOUSE
θ value	2.36792 (rank : 170)	NC score	0.097189 (rank : 113)
Query Neighborhood Hits	283	Target Neighborhood Hits	339	Shared Neighborhood Hits	80
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN575_MOUSE
θ value	2.36792 (rank : 171)	NC score	-0.000120 (rank : 439)
Query Neighborhood Hits	283	Target Neighborhood Hits	715	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ANR26_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.041254 (rank : 347)
Query Neighborhood Hits	283	Target Neighborhood Hits	1614	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ATX1_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.043262 (rank : 341)
Query Neighborhood Hits	283	Target Neighborhood Hits	264	Shared Neighborhood Hits	28
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

BPAEA_MOUSE
θ value	3.0926 (rank : 174)	NC score	0.038423 (rank : 352)
Query Neighborhood Hits	283	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAPS2_MOUSE
θ value	3.0926 (rank : 175)	NC score	0.087434 (rank : 134)
Query Neighborhood Hits	283	Target Neighborhood Hits	78	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

CCD71_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.032857 (rank : 369)
Query Neighborhood Hits	283	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IV32, Q6IPE2, Q9H8H4, Q9H9F1	Gene names	CCDC71
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 71.

CENPF_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.050881 (rank : 306)
Query Neighborhood Hits	283	Target Neighborhood Hits	1932	Shared Neighborhood Hits	89
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DEND_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.034013 (rank : 365)
Query Neighborhood Hits	283	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

LIPA2_MOUSE
θ value	3.0926 (rank : 179)	NC score	0.056902 (rank : 247)
Query Neighborhood Hits	283	Target Neighborhood Hits	1282	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LMO7_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.047413 (rank : 329)
Query Neighborhood Hits	283	Target Neighborhood Hits	507	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LPP_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.029978 (rank : 380)
Query Neighborhood Hits	283	Target Neighborhood Hits	775	Shared Neighborhood Hits	69
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGC1_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.037250 (rank : 354)
Query Neighborhood Hits	283	Target Neighborhood Hits	431	Shared Neighborhood Hits	56
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PHLPP_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.021622 (rank : 403)
Query Neighborhood Hits	283	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

SART3_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.023138 (rank : 394)
Query Neighborhood Hits	283	Target Neighborhood Hits	341	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

SEM6B_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.011518 (rank : 426)
Query Neighborhood Hits	283	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SMR3A_HUMAN
θ value	3.0926 (rank : 186)	NC score	0.087395 (rank : 135)
Query Neighborhood Hits	283	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SORC3_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.012859 (rank : 425)
Query Neighborhood Hits	283	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SPEG_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.022493 (rank : 397)
Query Neighborhood Hits	283	Target Neighborhood Hits	1959	Shared Neighborhood Hits	109
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRIPB_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.051196 (rank : 300)
Query Neighborhood Hits	283	Target Neighborhood Hits	1587	Shared Neighborhood Hits	81
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

WASL_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.087391 (rank : 136)
Query Neighborhood Hits	283	Target Neighborhood Hits	312	Shared Neighborhood Hits	75
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

XRCC1_MOUSE
θ value	3.0926 (rank : 191)	NC score	0.038149 (rank : 353)
Query Neighborhood Hits	283	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZN414_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.030571 (rank : 377)
Query Neighborhood Hits	283	Target Neighborhood Hits	473	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ANR26_MOUSE
θ value	4.03905 (rank : 193)	NC score	0.045553 (rank : 335)
Query Neighborhood Hits	283	Target Neighborhood Hits	1554	Shared Neighborhood Hits	76
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR35_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.032394 (rank : 371)
Query Neighborhood Hits	283	Target Neighborhood Hits	784	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ATX1_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.034059 (rank : 364)
Query Neighborhood Hits	283	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

CAC1G_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.020147 (rank : 407)
Query Neighborhood Hits	283	Target Neighborhood Hits	587	Shared Neighborhood Hits	57
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CUTL1_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.049184 (rank : 324)
Query Neighborhood Hits	283	Target Neighborhood Hits	1574	Shared Neighborhood Hits	94
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DOC10_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.088553 (rank : 132)
Query Neighborhood Hits	283	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

FGD3_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.105195 (rank : 94)
Query Neighborhood Hits	283	Target Neighborhood Hits	257	Shared Neighborhood Hits	39
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FOG1_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.018662 (rank : 412)
Query Neighborhood Hits	283	Target Neighborhood Hits	981	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HGS_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.053272 (rank : 272)
Query Neighborhood Hits	283	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

I17RA_MOUSE
θ value	4.03905 (rank : 202)	NC score	0.016905 (rank : 418)
Query Neighborhood Hits	283	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

LCP2_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.054189 (rank : 262)
Query Neighborhood Hits	283	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LUZP1_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.044395 (rank : 339)
Query Neighborhood Hits	283	Target Neighborhood Hits	940	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MAP1A_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.062518 (rank : 216)
Query Neighborhood Hits	283	Target Neighborhood Hits	1626	Shared Neighborhood Hits	113
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MEGF9_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.020668 (rank : 405)
Query Neighborhood Hits	283	Target Neighborhood Hits	896	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MLL3_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.062446 (rank : 218)
Query Neighborhood Hits	283	Target Neighborhood Hits	1644	Shared Neighborhood Hits	123
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MMP21_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.008380 (rank : 430)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MUCDL_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.049127 (rank : 325)
Query Neighborhood Hits	283	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NRX2A_HUMAN
θ value	4.03905 (rank : 210)	NC score	0.022267 (rank : 399)
Query Neighborhood Hits	283	Target Neighborhood Hits	614	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.034530 (rank : 361)
Query Neighborhood Hits	283	Target Neighborhood Hits	481	Shared Neighborhood Hits	49
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PHLB2_MOUSE
θ value	4.03905 (rank : 212)	NC score	0.101456 (rank : 108)
Query Neighborhood Hits	283	Target Neighborhood Hits	1016	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLEK_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.213676 (rank : 32)
Query Neighborhood Hits	283	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PSL1_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.054239 (rank : 261)
Query Neighborhood Hits	283	Target Neighborhood Hits	650	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SEPT9_HUMAN
θ value	4.03905 (rank : 215)	NC score	0.027908 (rank : 386)
Query Neighborhood Hits	283	Target Neighborhood Hits	706	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

STAT6_HUMAN
θ value	4.03905 (rank : 216)	NC score	0.015674 (rank : 419)
Query Neighborhood Hits	283	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

TCP10_HUMAN
θ value	4.03905 (rank : 217)	NC score	0.032196 (rank : 373)
Query Neighborhood Hits	283	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

TFE3_HUMAN
θ value	4.03905 (rank : 218)	NC score	0.019193 (rank : 411)
Query Neighborhood Hits	283	Target Neighborhood Hits	190	Shared Neighborhood Hits	15
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

ULK1_HUMAN
θ value	4.03905 (rank : 219)	NC score	0.004062 (rank : 433)
Query Neighborhood Hits	283	Target Neighborhood Hits	1121	Shared Neighborhood Hits	44
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

AB1IP_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.062110 (rank : 221)
Query Neighborhood Hits	283	Target Neighborhood Hits	213	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ABI1_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.019641 (rank : 408)
Query Neighborhood Hits	283	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ARI1A_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.067338 (rank : 188)
Query Neighborhood Hits	283	Target Neighborhood Hits	787	Shared Neighborhood Hits	85
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

C43BP_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.122092 (rank : 75)
Query Neighborhood Hits	283	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CAPS2_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.080691 (rank : 148)
Query Neighborhood Hits	283	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

CJ108_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.039863 (rank : 349)
Query Neighborhood Hits	283	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CUTL2_MOUSE
θ value	5.27518 (rank : 226)	NC score	0.042398 (rank : 344)
Query Neighborhood Hits	283	Target Neighborhood Hits	771	Shared Neighborhood Hits	66
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DAPP1_MOUSE
θ value	5.27518 (rank : 227)	NC score	0.190566 (rank : 37)
Query Neighborhood Hits	283	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DOK2_MOUSE
θ value	5.27518 (rank : 228)	NC score	0.021854 (rank : 402)
Query Neighborhood Hits	283	Target Neighborhood Hits	244	Shared Neighborhood Hits	25
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

EGFR_HUMAN
θ value	5.27518 (rank : 229)	NC score	-0.001016 (rank : 440)
Query Neighborhood Hits	283	Target Neighborhood Hits	939	Shared Neighborhood Hits	17
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

FMN1B_MOUSE
θ value	5.27518 (rank : 230)	NC score	0.043176 (rank : 342)
Query Neighborhood Hits	283	Target Neighborhood Hits	447	Shared Neighborhood Hits	64
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FOLC_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.017187 (rank : 416)
Query Neighborhood Hits	283	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

FYCO1_MOUSE
θ value	5.27518 (rank : 232)	NC score	0.062947 (rank : 214)
Query Neighborhood Hits	283	Target Neighborhood Hits	1059	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

JIP1_MOUSE
θ value	5.27518 (rank : 233)	NC score	0.027510 (rank : 388)
Query Neighborhood Hits	283	Target Neighborhood Hits	259	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PHF3_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.035119 (rank : 356)
Query Neighborhood Hits	283	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PHLB2_HUMAN
θ value	5.27518 (rank : 235)	NC score	0.100100 (rank : 110)
Query Neighborhood Hits	283	Target Neighborhood Hits	964	Shared Neighborhood Hits	79
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLPP_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.026039 (rank : 391)
Query Neighborhood Hits	283	Target Neighborhood Hits	604	Shared Neighborhood Hits	46
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

RUFY2_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.059214 (rank : 234)
Query Neighborhood Hits	283	Target Neighborhood Hits	1208	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUSC2_MOUSE
θ value	5.27518 (rank : 238)	NC score	0.032456 (rank : 370)
Query Neighborhood Hits	283	Target Neighborhood Hits	305	Shared Neighborhood Hits	42
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SF3B1_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.059039 (rank : 236)
Query Neighborhood Hits	283	Target Neighborhood Hits	341	Shared Neighborhood Hits	40
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.059028 (rank : 237)
Query Neighborhood Hits	283	Target Neighborhood Hits	352	Shared Neighborhood Hits	41
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SMAD4_MOUSE
θ value	5.27518 (rank : 241)	NC score	0.009644 (rank : 428)
Query Neighborhood Hits	283	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

C43BP_MOUSE
θ value	6.88961 (rank : 242)	NC score	0.124668 (rank : 73)
Query Neighborhood Hits	283	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CADH4_MOUSE
θ value	6.88961 (rank : 243)	NC score	0.001999 (rank : 436)
Query Neighborhood Hits	283	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	P39038	Gene names	Cdh4
Domain Architecture
Description	Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD).

CSF1_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.034678 (rank : 359)
Query Neighborhood Hits	283	Target Neighborhood Hits	258	Shared Neighborhood Hits	32
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CTTB2_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.033954 (rank : 366)
Query Neighborhood Hits	283	Target Neighborhood Hits	1061	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

EP15R_HUMAN
θ value	6.88961 (rank : 246)	NC score	0.045578 (rank : 334)
Query Neighborhood Hits	283	Target Neighborhood Hits	1083	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

GAB1_MOUSE
θ value	6.88961 (rank : 247)	NC score	0.119184 (rank : 78)
Query Neighborhood Hits	283	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GOGA5_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.056431 (rank : 251)
Query Neighborhood Hits	283	Target Neighborhood Hits	1168	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

K1C19_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.022192 (rank : 400)
Query Neighborhood Hits	283	Target Neighborhood Hits	320	Shared Neighborhood Hits	32
SwissProt Accessions	P08727, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4	Gene names	KRT19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

NCOR1_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.022511 (rank : 396)
Query Neighborhood Hits	283	Target Neighborhood Hits	577	Shared Neighborhood Hits	44
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NVL_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.003743 (rank : 434)
Query Neighborhood Hits	283	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PDLI4_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.009406 (rank : 429)
Query Neighborhood Hits	283	Target Neighborhood Hits	233	Shared Neighborhood Hits	10
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI7_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.014970 (rank : 422)
Query Neighborhood Hits	283	Target Neighborhood Hits	547	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD2_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.036666 (rank : 355)
Query Neighborhood Hits	283	Target Neighborhood Hits	772	Shared Neighborhood Hits	69
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RBNS5_MOUSE
θ value	6.88961 (rank : 255)	NC score	0.041050 (rank : 348)
Query Neighborhood Hits	283	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RTN1_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.030247 (rank : 379)
Query Neighborhood Hits	283	Target Neighborhood Hits	189	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SEM6C_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.017142 (rank : 417)
Query Neighborhood Hits	283	Target Neighborhood Hits	352	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

USF2_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.030369 (rank : 378)
Query Neighborhood Hits	283	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	6.88961 (rank : 259)	NC score	0.032864 (rank : 368)
Query Neighborhood Hits	283	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

ZN319_MOUSE
θ value	6.88961 (rank : 260)	NC score	-0.003343 (rank : 441)
Query Neighborhood Hits	283	Target Neighborhood Hits	762	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZNHI4_MOUSE
θ value	6.88961 (rank : 261)	NC score	0.041697 (rank : 345)
Query Neighborhood Hits	283	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

ACK1_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.006879 (rank : 432)
Query Neighborhood Hits	283	Target Neighborhood Hits	1140	Shared Neighborhood Hits	71
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ADAM9_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.001925 (rank : 437)
Query Neighborhood Hits	283	Target Neighborhood Hits	325	Shared Neighborhood Hits	14
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

AHTF1_MOUSE
θ value	8.99809 (rank : 264)	NC score	0.020517 (rank : 406)
Query Neighborhood Hits	283	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

DAPP1_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.184176 (rank : 39)
Query Neighborhood Hits	283	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

FOG1_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.014310 (rank : 423)
Query Neighborhood Hits	283	Target Neighborhood Hits	1237	Shared Neighborhood Hits	77
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GRIP1_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.019538 (rank : 409)
Query Neighborhood Hits	283	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

HKR3_HUMAN
θ value	8.99809 (rank : 268)	NC score	-0.003350 (rank : 442)
Query Neighborhood Hits	283	Target Neighborhood Hits	839	Shared Neighborhood Hits	17
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

K0179_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.018307 (rank : 413)
Query Neighborhood Hits	283	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q14684, Q8TBZ4	Gene names	KIAA0179
Domain Architecture
Description	Protein KIAA0179.

K1914_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.077131 (rank : 158)
Query Neighborhood Hits	283	Target Neighborhood Hits	255	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1914_MOUSE
θ value	8.99809 (rank : 271)	NC score	0.068341 (rank : 184)
Query Neighborhood Hits	283	Target Neighborhood Hits	216	Shared Neighborhood Hits	38
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1C16_MOUSE
θ value	8.99809 (rank : 272)	NC score	0.028216 (rank : 385)
Query Neighborhood Hits	283	Target Neighborhood Hits	444	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z2K1	Gene names	Krt16, Krt1-16
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

MD1L1_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.048418 (rank : 326)
Query Neighborhood Hits	283	Target Neighborhood Hits	893	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MDC1_MOUSE
θ value	8.99809 (rank : 274)	NC score	0.058071 (rank : 242)
Query Neighborhood Hits	283	Target Neighborhood Hits	998	Shared Neighborhood Hits	83
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL2_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.074256 (rank : 164)
Query Neighborhood Hits	283	Target Neighborhood Hits	1788	Shared Neighborhood Hits	142
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MRCKB_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.022176 (rank : 401)
Query Neighborhood Hits	283	Target Neighborhood Hits	2180	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

OBSCN_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.012981 (rank : 424)
Query Neighborhood Hits	283	Target Neighborhood Hits	1931	Shared Neighborhood Hits	87
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PERI_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.031942 (rank : 374)
Query Neighborhood Hits	283	Target Neighborhood Hits	506	Shared Neighborhood Hits	45
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

PRGC2_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.047591 (rank : 328)
Query Neighborhood Hits	283	Target Neighborhood Hits	272	Shared Neighborhood Hits	39
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

SOX13_MOUSE
θ value	8.99809 (rank : 280)	NC score	0.026477 (rank : 390)
Query Neighborhood Hits	283	Target Neighborhood Hits	495	Shared Neighborhood Hits	46
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TXND2_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.045756 (rank : 333)
Query Neighborhood Hits	283	Target Neighborhood Hits	793	Shared Neighborhood Hits	57
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASIP_MOUSE
θ value	8.99809 (rank : 282)	NC score	0.103380 (rank : 98)
Query Neighborhood Hits	283	Target Neighborhood Hits	392	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WBS14_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.069526 (rank : 177)
Query Neighborhood Hits	283	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

3BP1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.059657 (rank : 231)
Query Neighborhood Hits	283	Target Neighborhood Hits	376	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ABR_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.066309 (rank : 194)
Query Neighborhood Hits	283	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ALEX_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.065654 (rank : 198)
Query Neighborhood Hits	283	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARHGF_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.062338 (rank : 219)
Query Neighborhood Hits	283	Target Neighborhood Hits	214	Shared Neighborhood Hits	60
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1B_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.053657 (rank : 267)
Query Neighborhood Hits	283	Target Neighborhood Hits	567	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ASPP1_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.053565 (rank : 268)
Query Neighborhood Hits	283	Target Neighborhood Hits	1244	Shared Neighborhood Hits	109
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.050487 (rank : 317)
Query Neighborhood Hits	283	Target Neighborhood Hits	1156	Shared Neighborhood Hits	91
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATN1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.069726 (rank : 176)
Query Neighborhood Hits	283	Target Neighborhood Hits	676	Shared Neighborhood Hits	84
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

AZI1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.052072 (rank : 282)
Query Neighborhood Hits	283	Target Neighborhood Hits	1000	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BASP_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.061607 (rank : 225)
Query Neighborhood Hits	283	Target Neighborhood Hits	321	Shared Neighborhood Hits	46
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.065119 (rank : 202)
Query Neighborhood Hits	283	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.068233 (rank : 185)
Query Neighborhood Hits	283	Target Neighborhood Hits	931	Shared Neighborhood Hits	106
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.078066 (rank : 155)
Query Neighborhood Hits	283	Target Neighborhood Hits	947	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCR_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.066950 (rank : 190)
Query Neighborhood Hits	283	Target Neighborhood Hits	204	Shared Neighborhood Hits	33
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BIG1_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.109589 (rank : 90)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.110635 (rank : 89)
Query Neighborhood Hits	283	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BRD4_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.050773 (rank : 309)
Query Neighborhood Hits	283	Target Neighborhood Hits	845	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BSN_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.101863 (rank : 106)
Query Neighborhood Hits	283	Target Neighborhood Hits	1537	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CCNK_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.053361 (rank : 271)
Query Neighborhood Hits	283	Target Neighborhood Hits	350	Shared Neighborhood Hits	67
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CENA2_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.089407 (rank : 129)
Query Neighborhood Hits	283	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND3_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.102818 (rank : 100)
Query Neighborhood Hits	283	Target Neighborhood Hits	275	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.096004 (rank : 118)
Query Neighborhood Hits	283	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CENG1_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.051626 (rank : 290)
Query Neighborhood Hits	283	Target Neighborhood Hits	531	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CJ078_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.082616 (rank : 142)
Query Neighborhood Hits	283	Target Neighborhood Hits	559	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN032_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.075981 (rank : 160)
Query Neighborhood Hits	283	Target Neighborhood Hits	267	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.056759 (rank : 249)
Query Neighborhood Hits	283	Target Neighborhood Hits	233	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CP250_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.051029 (rank : 304)
Query Neighborhood Hits	283	Target Neighborhood Hits	1805	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CPSF6_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.051202 (rank : 299)
Query Neighborhood Hits	283	Target Neighborhood Hits	359	Shared Neighborhood Hits	56
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.051431 (rank : 293)
Query Neighborhood Hits	283	Target Neighborhood Hits	356	Shared Neighborhood Hits	56
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRTC1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.050439 (rank : 318)
Query Neighborhood Hits	283	Target Neighborhood Hits	319	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS016_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.061998 (rank : 222)
Query Neighborhood Hits	283	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DDEF1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.068698 (rank : 182)
Query Neighborhood Hits	283	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.063965 (rank : 207)
Query Neighborhood Hits	283	Target Neighborhood Hits	599	Shared Neighborhood Hits	73
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.065972 (rank : 196)
Query Neighborhood Hits	283	Target Neighborhood Hits	625	Shared Neighborhood Hits	71
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.071386 (rank : 170)
Query Neighborhood Hits	283	Target Neighborhood Hits	353	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.065145 (rank : 200)
Query Neighborhood Hits	283	Target Neighborhood Hits	324	Shared Neighborhood Hits	32
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKK_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.082340 (rank : 143)
Query Neighborhood Hits	283	Target Neighborhood Hits	378	Shared Neighborhood Hits	77
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DOT1L_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.050534 (rank : 316)
Query Neighborhood Hits	283	Target Neighborhood Hits	660	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DYN1_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.078940 (rank : 150)
Query Neighborhood Hits	283	Target Neighborhood Hits	216	Shared Neighborhood Hits	70
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.072674 (rank : 168)
Query Neighborhood Hits	283	Target Neighborhood Hits	168	Shared Neighborhood Hits	56
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

ECT2_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.050374 (rank : 319)
Query Neighborhood Hits	283	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.052097 (rank : 281)
Query Neighborhood Hits	283	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EEA1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.050819 (rank : 308)
Query Neighborhood Hits	283	Target Neighborhood Hits	1796	Shared Neighborhood Hits	85
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.051406 (rank : 295)
Query Neighborhood Hits	283	Target Neighborhood Hits	1637	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ENAH_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.069769 (rank : 175)
Query Neighborhood Hits	283	Target Neighborhood Hits	919	Shared Neighborhood Hits	107
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.066909 (rank : 191)
Query Neighborhood Hits	283	Target Neighborhood Hits	821	Shared Neighborhood Hits	83
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FBX8_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.101633 (rank : 107)
Query Neighborhood Hits	283	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.102088 (rank : 104)
Query Neighborhood Hits	283	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FGD2_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.090702 (rank : 125)
Query Neighborhood Hits	283	Target Neighborhood Hits	151	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.095018 (rank : 120)
Query Neighborhood Hits	283	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.081958 (rank : 145)
Query Neighborhood Hits	283	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD4_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.099082 (rank : 112)
Query Neighborhood Hits	283	Target Neighborhood Hits	219	Shared Neighborhood Hits	48
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.100193 (rank : 109)
Query Neighborhood Hits	283	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FMNL_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.050942 (rank : 305)
Query Neighborhood Hits	283	Target Neighborhood Hits	529	Shared Neighborhood Hits	91
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FYCO1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.063511 (rank : 209)
Query Neighborhood Hits	283	Target Neighborhood Hits	1149	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GAB1_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.115616 (rank : 84)
Query Neighborhood Hits	283	Target Neighborhood Hits	279	Shared Neighborhood Hits	63
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GBF1_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.118900 (rank : 79)
Query Neighborhood Hits	283	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GGN_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.059237 (rank : 233)
Query Neighborhood Hits	283	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.058357 (rank : 240)
Query Neighborhood Hits	283	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GOGB1_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.052511 (rank : 277)
Query Neighborhood Hits	283	Target Neighborhood Hits	2297	Shared Neighborhood Hits	106
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GSCR1_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.064935 (rank : 204)
Query Neighborhood Hits	283	Target Neighborhood Hits	674	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IQEC1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.099195 (rank : 111)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.096427 (rank : 116)
Query Neighborhood Hits	283	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.110787 (rank : 88)
Query Neighborhood Hits	283	Target Neighborhood Hits	403	Shared Neighborhood Hits	71
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.113176 (rank : 87)
Query Neighborhood Hits	283	Target Neighborhood Hits	417	Shared Neighborhood Hits	77
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.107470 (rank : 92)
Query Neighborhood Hits	283	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.115218 (rank : 86)
Query Neighborhood Hits	283	Target Neighborhood Hits	274	Shared Neighborhood Hits	52
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

ITSN1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.051422 (rank : 294)
Query Neighborhood Hits	283	Target Neighborhood Hits	1757	Shared Neighborhood Hits	95
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.054797 (rank : 259)
Query Neighborhood Hits	283	Target Neighborhood Hits	1669	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MARCS_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.051897 (rank : 286)
Query Neighborhood Hits	283	Target Neighborhood Hits	227	Shared Neighborhood Hits	42
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MBD6_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.055923 (rank : 253)
Query Neighborhood Hits	283	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.068674 (rank : 183)
Query Neighborhood Hits	283	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MILK1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.052252 (rank : 279)
Query Neighborhood Hits	283	Target Neighborhood Hits	427	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.050242 (rank : 320)
Query Neighborhood Hits	283	Target Neighborhood Hits	1291	Shared Neighborhood Hits	104
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL4_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.053725 (rank : 266)
Query Neighborhood Hits	283	Target Neighborhood Hits	722	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MTMR5_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.061666 (rank : 224)
Query Neighborhood Hits	283	Target Neighborhood Hits	141	Shared Neighborhood Hits	36
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MUC1_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.051495 (rank : 291)
Query Neighborhood Hits	283	Target Neighborhood Hits	975	Shared Neighborhood Hits	78
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.087505 (rank : 133)
Query Neighborhood Hits	283	Target Neighborhood Hits	538	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.067323 (rank : 189)
Query Neighborhood Hits	283	Target Neighborhood Hits	1866	Shared Neighborhood Hits	126
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOR2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.056773 (rank : 248)
Query Neighborhood Hits	283	Target Neighborhood Hits	870	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.051915 (rank : 285)
Query Neighborhood Hits	283	Target Neighborhood Hits	790	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NFH_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.065317 (rank : 199)
Query Neighborhood Hits	283	Target Neighborhood Hits	1242	Shared Neighborhood Hits	102
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.053799 (rank : 265)
Query Neighborhood Hits	283	Target Neighborhood Hits	452	Shared Neighborhood Hits	51
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

OSB11_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.051868 (rank : 287)
Query Neighborhood Hits	283	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.052491 (rank : 278)
Query Neighborhood Hits	283	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL3_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.050587 (rank : 315)
Query Neighborhood Hits	283	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL9_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.069898 (rank : 174)
Query Neighborhood Hits	283	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

PCNT_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.052712 (rank : 275)
Query Neighborhood Hits	283	Target Neighborhood Hits	1551	Shared Neighborhood Hits	87
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCQAP_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.062983 (rank : 212)
Query Neighborhood Hits	283	Target Neighborhood Hits	549	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.052646 (rank : 276)
Query Neighborhood Hits	283	Target Neighborhood Hits	506	Shared Neighborhood Hits	69
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PKHA3_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.096303 (rank : 117)
Query Neighborhood Hits	283	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.107334 (rank : 93)
Query Neighborhood Hits	283	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHF1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.060182 (rank : 229)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.060348 (rank : 228)
Query Neighborhood Hits	283	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.062957 (rank : 213)
Query Neighborhood Hits	283	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.065140 (rank : 201)
Query Neighborhood Hits	283	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PLEK2_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.148617 (rank : 60)
Query Neighborhood Hits	283	Target Neighborhood Hits	101	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.141624 (rank : 62)
Query Neighborhood Hits	283	Target Neighborhood Hits	96	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.185431 (rank : 38)
Query Neighborhood Hits	283	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PRB3_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.115256 (rank : 85)
Query Neighborhood Hits	283	Target Neighborhood Hits	318	Shared Neighborhood Hits	72
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.120420 (rank : 77)
Query Neighborhood Hits	283	Target Neighborhood Hits	330	Shared Neighborhood Hits	80
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PREX1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.051440 (rank : 292)
Query Neighborhood Hits	283	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.078813 (rank : 151)
Query Neighborhood Hits	283	Target Neighborhood Hits	764	Shared Neighborhood Hits	85
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.063272 (rank : 211)
Query Neighborhood Hits	283	Target Neighborhood Hits	624	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.130917 (rank : 68)
Query Neighborhood Hits	283	Target Neighborhood Hits	385	Shared Neighborhood Hits	85
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.130726 (rank : 69)
Query Neighborhood Hits	283	Target Neighborhood Hits	347	Shared Neighborhood Hits	77
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.089531 (rank : 128)
Query Neighborhood Hits	283	Target Neighborhood Hits	108	Shared Neighborhood Hits	30
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.077205 (rank : 157)
Query Neighborhood Hits	283	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.086616 (rank : 138)
Query Neighborhood Hits	283	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.086985 (rank : 137)
Query Neighborhood Hits	283	Target Neighborhood Hits	460	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PSD3_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.165822 (rank : 44)
Query Neighborhood Hits	283	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.134379 (rank : 66)
Query Neighborhood Hits	283	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.118447 (rank : 80)
Query Neighborhood Hits	283	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PYGO2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.058030 (rank : 243)
Query Neighborhood Hits	283	Target Neighborhood Hits	189	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RAPH1_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.077800 (rank : 156)
Query Neighborhood Hits	283	Target Neighborhood Hits	593	Shared Neighborhood Hits	103
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RASA1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.073165 (rank : 166)
Query Neighborhood Hits	283	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RASA2_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.050880 (rank : 307)
Query Neighborhood Hits	283	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.061770 (rank : 223)
Query Neighborhood Hits	283	Target Neighborhood Hits	159	Shared Neighborhood Hits	38
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.059671 (rank : 230)
Query Neighborhood Hits	283	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.050710 (rank : 312)
Query Neighborhood Hits	283	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RBP1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.051750 (rank : 288)
Query Neighborhood Hits	283	Target Neighborhood Hits	521	Shared Neighborhood Hits	45
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RERE_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.057715 (rank : 244)
Query Neighborhood Hits	283	Target Neighborhood Hits	779	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.063487 (rank : 210)
Query Neighborhood Hits	283	Target Neighborhood Hits	785	Shared Neighborhood Hits	97
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RFIP3_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.055701 (rank : 256)
Query Neighborhood Hits	283	Target Neighborhood Hits	1055	Shared Neighborhood Hits	86
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RHG26_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.051674 (rank : 289)
Query Neighborhood Hits	283	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RP1L1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.051285 (rank : 298)
Query Neighborhood Hits	283	Target Neighborhood Hits	1072	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RUFY1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.050670 (rank : 314)
Query Neighborhood Hits	283	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.058956 (rank : 239)
Query Neighborhood Hits	283	Target Neighborhood Hits	820	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SC24D_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.050227 (rank : 321)
Query Neighborhood Hits	283	Target Neighborhood Hits	173	Shared Neighborhood Hits	34
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SELPL_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.050013 (rank : 323)
Query Neighborhood Hits	283	Target Neighborhood Hits	588	Shared Neighborhood Hits	59
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SET1A_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.063934 (rank : 208)
Query Neighborhood Hits	283	Target Neighborhood Hits	690	Shared Neighborhood Hits	86
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFPQ_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.075492 (rank : 161)
Query Neighborhood Hits	283	Target Neighborhood Hits	986	Shared Neighborhood Hits	111
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.069038 (rank : 180)
Query Neighborhood Hits	283	Target Neighborhood Hits	958	Shared Neighborhood Hits	106
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.051980 (rank : 284)
Query Neighborhood Hits	283	Target Neighborhood Hits	368	Shared Neighborhood Hits	50
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.051320 (rank : 297)
Query Neighborhood Hits	283	Target Neighborhood Hits	180	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAP1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.051092 (rank : 302)
Query Neighborhood Hits	283	Target Neighborhood Hits	98	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.050093 (rank : 322)
Query Neighborhood Hits	283	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SON_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.062260 (rank : 220)
Query Neighborhood Hits	283	Target Neighborhood Hits	1568	Shared Neighborhood Hits	111
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.052743 (rank : 273)
Query Neighborhood Hits	283	Target Neighborhood Hits	957	Shared Neighborhood Hits	90
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRRM2_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.101869 (rank : 105)
Query Neighborhood Hits	283	Target Neighborhood Hits	1296	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.084520 (rank : 140)
Query Neighborhood Hits	283	Target Neighborhood Hits	1470	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SWP70_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.122196 (rank : 74)
Query Neighborhood Hits	283	Target Neighborhood Hits	973	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.117682 (rank : 81)
Query Neighborhood Hits	283	Target Neighborhood Hits	1097	Shared Neighborhood Hits	107
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYN1_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.070147 (rank : 173)
Query Neighborhood Hits	283	Target Neighborhood Hits	419	Shared Neighborhood Hits	87
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.057191 (rank : 246)
Query Neighborhood Hits	283	Target Neighborhood Hits	363	Shared Neighborhood Hits	74
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.053460 (rank : 270)
Query Neighborhood Hits	283	Target Neighborhood Hits	516	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TAF4_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.073938 (rank : 165)
Query Neighborhood Hits	283	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TBCD2_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.070856 (rank : 172)
Query Neighborhood Hits	283	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TGON2_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.053920 (rank : 264)
Query Neighborhood Hits	283	Target Neighborhood Hits	1037	Shared Neighborhood Hits	74
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIAM1_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.050673 (rank : 313)
Query Neighborhood Hits	283	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

WASF2_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.052058 (rank : 283)
Query Neighborhood Hits	283	Target Neighborhood Hits	315	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASIP_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.104424 (rank : 95)
Query Neighborhood Hits	283	Target Neighborhood Hits	458	Shared Neighborhood Hits	85
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASP_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.050754 (rank : 310)
Query Neighborhood Hits	283	Target Neighborhood Hits	195	Shared Neighborhood Hits	52
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.055839 (rank : 255)
Query Neighborhood Hits	283	Target Neighborhood Hits	223	Shared Neighborhood Hits	54
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.069297 (rank : 179)
Query Neighborhood Hits	283	Target Neighborhood Hits	354	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.064444 (rank : 206)
Query Neighborhood Hits	283	Target Neighborhood Hits	362	Shared Neighborhood Hits	65
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.074315 (rank : 163)
Query Neighborhood Hits	283	Target Neighborhood Hits	329	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.078768 (rank : 152)
Query Neighborhood Hits	283	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.055381 (rank : 257)
Query Neighborhood Hits	283	Target Neighborhood Hits	505	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

Hits sorted by NC score

PKHA4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	283	Target Neighborhood Hits	283	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
NC score	0.948125 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	283	Target Neighborhood Hits	202	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_HUMAN
NC score	0.695918 (rank : 3)	θ value	6.17384e-33 (rank : 4)
Query Neighborhood Hits	283	Target Neighborhood Hits	556	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.690181 (rank : 4)	θ value	2.34606e-32 (rank : 5)
Query Neighborhood Hits	283	Target Neighborhood Hits	591	Shared Neighborhood Hits	134
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA5_HUMAN
NC score	0.641537 (rank : 5)	θ value	4.27553e-34 (rank : 3)
Query Neighborhood Hits	283	Target Neighborhood Hits	455	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CNKR1_HUMAN
NC score	0.510786 (rank : 6)	θ value	3.29651e-10 (rank : 6)
Query Neighborhood Hits	283	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_MOUSE
NC score	0.422472 (rank : 7)	θ value	2.61198e-07 (rank : 8)
Query Neighborhood Hits	283	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.422019 (rank : 8)	θ value	2.61198e-07 (rank : 7)
Query Neighborhood Hits	283	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH3_HUMAN
NC score	0.328942 (rank : 9)	θ value	4.1701e-05 (rank : 15)
Query Neighborhood Hits	283	Target Neighborhood Hits	137	Shared Neighborhood Hits	70
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
NC score	0.328067 (rank : 10)	θ value	4.1701e-05 (rank : 13)
Query Neighborhood Hits	283	Target Neighborhood Hits	184	Shared Neighborhood Hits	79
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.327286 (rank : 11)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	283	Target Neighborhood Hits	176	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
NC score	0.324347 (rank : 12)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	283	Target Neighborhood Hits	175	Shared Neighborhood Hits	76
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.324104 (rank : 13)	θ value	1.87187e-05 (rank : 12)
Query Neighborhood Hits	283	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

PKHA1_HUMAN
NC score	0.319630 (rank : 14)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	283	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CYH3_MOUSE
NC score	0.319205 (rank : 15)	θ value	0.000786445 (rank : 20)
Query Neighborhood Hits	283	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
NC score	0.315710 (rank : 16)	θ value	0.00134147 (rank : 21)
Query Neighborhood Hits	283	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
NC score	0.312497 (rank : 17)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	283	Target Neighborhood Hits	134	Shared Neighborhood Hits	67
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

3BP2_HUMAN
NC score	0.311410 (rank : 18)	θ value	0.000786445 (rank : 19)
Query Neighborhood Hits	283	Target Neighborhood Hits	296	Shared Neighborhood Hits	69
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
NC score	0.303610 (rank : 19)	θ value	0.00390308 (rank : 28)
Query Neighborhood Hits	283	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PKHA1_MOUSE
NC score	0.300563 (rank : 20)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	283	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_MOUSE
NC score	0.294095 (rank : 21)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	283	Target Neighborhood Hits	116	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA2_HUMAN
NC score	0.285305 (rank : 22)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	283	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

RHG25_MOUSE
NC score	0.278579 (rank : 23)	θ value	7.59969e-07 (rank : 10)
Query Neighborhood Hits	283	Target Neighborhood Hits	492	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.277833 (rank : 24)	θ value	5.81887e-07 (rank : 9)
Query Neighborhood Hits	283	Target Neighborhood Hits	550	Shared Neighborhood Hits	105
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHB2_MOUSE
NC score	0.255777 (rank : 25)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	283	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

MRIP_MOUSE
NC score	0.240784 (rank : 26)	θ value	0.000270298 (rank : 17)
Query Neighborhood Hits	283	Target Neighborhood Hits	569	Shared Neighborhood Hits	101
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PKHB2_HUMAN
NC score	0.240620 (rank : 27)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	283	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB1_HUMAN
NC score	0.235535 (rank : 28)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	283	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

MRIP_HUMAN
NC score	0.224728 (rank : 29)	θ value	0.00869519 (rank : 35)
Query Neighborhood Hits	283	Target Neighborhood Hits	578	Shared Neighborhood Hits	99
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

ANLN_HUMAN
NC score	0.223233 (rank : 30)	θ value	0.00869519 (rank : 33)
Query Neighborhood Hits	283	Target Neighborhood Hits	222	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

PKHB1_MOUSE
NC score	0.217263 (rank : 31)	θ value	0.163984 (rank : 73)
Query Neighborhood Hits	283	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PLEK_HUMAN
NC score	0.213676 (rank : 32)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	283	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

TARA_MOUSE
NC score	0.206149 (rank : 33)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	283	Target Neighborhood Hits	1133	Shared Neighborhood Hits	142
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FGD5_MOUSE
NC score	0.199142 (rank : 34)	θ value	0.00298849 (rank : 27)
Query Neighborhood Hits	283	Target Neighborhood Hits	170	Shared Neighborhood Hits	42
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD5_HUMAN
NC score	0.195380 (rank : 35)	θ value	0.00390308 (rank : 30)
Query Neighborhood Hits	283	Target Neighborhood Hits	235	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

ANLN_MOUSE
NC score	0.192233 (rank : 36)	θ value	0.0193708 (rank : 37)
Query Neighborhood Hits	283	Target Neighborhood Hits	297	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DAPP1_MOUSE
NC score	0.190566 (rank : 37)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	283	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PLEK_MOUSE
NC score	0.185431 (rank : 38)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	283	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

DAPP1_HUMAN
NC score	0.184176 (rank : 39)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	283	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CENB2_HUMAN
NC score	0.180474 (rank : 40)	θ value	0.000602161 (rank : 18)
Query Neighborhood Hits	283	Target Neighborhood Hits	425	Shared Neighborhood Hits	63
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

FGD6_MOUSE
NC score	0.176357 (rank : 41)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	283	Target Neighborhood Hits	282	Shared Neighborhood Hits	61
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

TARA_HUMAN
NC score	0.174339 (rank : 42)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	283	Target Neighborhood Hits	1626	Shared Neighborhood Hits	167
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CENB5_HUMAN
NC score	0.170370 (rank : 43)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	283	Target Neighborhood Hits	395	Shared Neighborhood Hits	65
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

PSD3_HUMAN
NC score	0.165822 (rank : 44)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	283	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CENB1_HUMAN
NC score	0.165800 (rank : 45)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	283	Target Neighborhood Hits	383	Shared Neighborhood Hits	67
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

FARP2_MOUSE
NC score	0.162790 (rank : 46)	θ value	0.00390308 (rank : 29)
Query Neighborhood Hits	283	Target Neighborhood Hits	209	Shared Neighborhood Hits	54
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD6_HUMAN
NC score	0.161212 (rank : 47)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	283	Target Neighborhood Hits	237	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD1_MOUSE
NC score	0.161020 (rank : 48)	θ value	0.00665767 (rank : 32)
Query Neighborhood Hits	283	Target Neighborhood Hits	387	Shared Neighborhood Hits	72
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.160238 (rank : 49)	θ value	0.0193708 (rank : 38)
Query Neighborhood Hits	283	Target Neighborhood Hits	367	Shared Neighborhood Hits	75
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FARP2_HUMAN
NC score	0.159877 (rank : 50)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	283	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP1_HUMAN
NC score	0.156896 (rank : 51)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	283	Target Neighborhood Hits	241	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

OSBP1_HUMAN
NC score	0.156638 (rank : 52)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	283	Target Neighborhood Hits	180	Shared Neighborhood Hits	51
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

DGKH_HUMAN
NC score	0.156176 (rank : 53)	θ value	0.00869519 (rank : 34)
Query Neighborhood Hits	283	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

CEND2_HUMAN
NC score	0.155792 (rank : 54)	θ value	0.0431538 (rank : 46)
Query Neighborhood Hits	283	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CENA1_HUMAN
NC score	0.155533 (rank : 55)	θ value	0.0431538 (rank : 45)
Query Neighborhood Hits	283	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CEND1_HUMAN
NC score	0.155245 (rank : 56)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	283	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

GNRP_MOUSE
NC score	0.149422 (rank : 57)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	283	Target Neighborhood Hits	191	Shared Neighborhood Hits	51
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GAB2_HUMAN
NC score	0.148895 (rank : 58)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	283	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GNRP_HUMAN
NC score	0.148804 (rank : 59)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	283	Target Neighborhood Hits	239	Shared Neighborhood Hits	56
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

PLEK2_HUMAN
NC score	0.148617 (rank : 60)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	283	Target Neighborhood Hits	101	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

GAB2_MOUSE
NC score	0.146778 (rank : 61)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	283	Target Neighborhood Hits	220	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PLEK2_MOUSE
NC score	0.141624 (rank : 62)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	283	Target Neighborhood Hits	96	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PHLB1_MOUSE
NC score	0.140932 (rank : 63)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	283	Target Neighborhood Hits	678	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_HUMAN
NC score	0.140879 (rank : 64)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	283	Target Neighborhood Hits	1038	Shared Neighborhood Hits	119
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SRRM1_HUMAN
NC score	0.138118 (rank : 65)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	283	Target Neighborhood Hits	690	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PSD4_HUMAN
NC score	0.134379 (rank : 66)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	283	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

SRRM1_MOUSE
NC score	0.131358 (rank : 67)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	283	Target Neighborhood Hits	966	Shared Neighborhood Hits	113
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PRP1_HUMAN
NC score	0.130917 (rank : 68)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	283	Target Neighborhood Hits	385	Shared Neighborhood Hits	85
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
NC score	0.130726 (rank : 69)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	283	Target Neighborhood Hits	347	Shared Neighborhood Hits	77
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

CEND1_MOUSE
NC score	0.128178 (rank : 70)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	283	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

OSBP2_HUMAN
NC score	0.125267 (rank : 71)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	283	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

CENA2_HUMAN
NC score	0.124915 (rank : 72)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	283	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

C43BP_MOUSE
NC score	0.124668 (rank : 73)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	283	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

SWP70_HUMAN
NC score	0.122196 (rank : 74)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	283	Target Neighborhood Hits	973	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

C43BP_HUMAN
NC score	0.122092 (rank : 75)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	283	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

MYO10_HUMAN
NC score	0.120833 (rank : 76)	θ value	0.000158464 (rank : 16)
Query Neighborhood Hits	283	Target Neighborhood Hits	920	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PRB4S_HUMAN
NC score	0.120420 (rank : 77)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	283	Target Neighborhood Hits	330	Shared Neighborhood Hits	80
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

GAB1_MOUSE
NC score	0.119184 (rank : 78)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	283	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GBF1_HUMAN
NC score	0.118900 (rank : 79)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	283	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

PSD4_MOUSE
NC score	0.118447 (rank : 80)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	283	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

SWP70_MOUSE
NC score	0.117682 (rank : 81)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	283	Target Neighborhood Hits	1097	Shared Neighborhood Hits	107
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

OSBP2_MOUSE
NC score	0.116601 (rank : 82)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	283	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

ALEX_HUMAN
NC score	0.116006 (rank : 83)	θ value	0.0330416 (rank : 43)
Query Neighborhood Hits	283	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GAB1_HUMAN
NC score	0.115616 (rank : 84)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	283	Target Neighborhood Hits	279	Shared Neighborhood Hits	63
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PRB3_HUMAN
NC score	0.115256 (rank : 85)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	283	Target Neighborhood Hits	318	Shared Neighborhood Hits	72
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

IQEC3_MOUSE
NC score	0.115218 (rank : 86)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	283	Target Neighborhood Hits	274	Shared Neighborhood Hits	52
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC2_MOUSE
NC score	0.113176 (rank : 87)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	283	Target Neighborhood Hits	417	Shared Neighborhood Hits	77
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.110787 (rank : 88)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	283	Target Neighborhood Hits	403	Shared Neighborhood Hits	71
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

BIG2_HUMAN
NC score	0.110635 (rank : 89)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	283	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BIG1_HUMAN
NC score	0.109589 (rank : 90)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

FA47B_HUMAN
NC score	0.107752 (rank : 91)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	283	Target Neighborhood Hits	431	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

IQEC3_HUMAN
NC score	0.107470 (rank : 92)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	283	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

PKHA3_MOUSE
NC score	0.107334 (rank : 93)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	283	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

FGD3_MOUSE
NC score	0.105195 (rank : 94)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	283	Target Neighborhood Hits	257	Shared Neighborhood Hits	39
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

WASIP_HUMAN
NC score	0.104424 (rank : 95)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	283	Target Neighborhood Hits	458	Shared Neighborhood Hits	85
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

DYN2_HUMAN
NC score	0.104386 (rank : 96)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	283	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DOCK9_MOUSE
NC score	0.104065 (rank : 97)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	283	Target Neighborhood Hits	79	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

WASIP_MOUSE
NC score	0.103380 (rank : 98)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	283	Target Neighborhood Hits	392	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PCLO_HUMAN
NC score	0.103380 (rank : 99)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	283	Target Neighborhood Hits	2046	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CEND3_HUMAN
NC score	0.102818 (rank : 100)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	283	Target Neighborhood Hits	275	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

BSN_MOUSE
NC score	0.102348 (rank : 101)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	283	Target Neighborhood Hits	2057	Shared Neighborhood Hits	155
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DYN2_MOUSE
NC score	0.102321 (rank : 102)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	283	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DOCK9_HUMAN
NC score	0.102197 (rank : 103)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	283	Target Neighborhood Hits	82	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

FBX8_MOUSE
NC score	0.102088 (rank : 104)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	283	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

SRRM2_HUMAN
NC score	0.101869 (rank : 105)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	283	Target Neighborhood Hits	1296	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BSN_HUMAN
NC score	0.101863 (rank : 106)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	283	Target Neighborhood Hits	1537	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

FBX8_HUMAN
NC score	0.101633 (rank : 107)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	283	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

PHLB2_MOUSE
NC score	0.101456 (rank : 108)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	283	Target Neighborhood Hits	1016	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

FGD4_MOUSE
NC score	0.100193 (rank : 109)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	283	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

PHLB2_HUMAN
NC score	0.100100 (rank : 110)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	283	Target Neighborhood Hits	964	Shared Neighborhood Hits	79
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

IQEC1_HUMAN
NC score	0.099195 (rank : 111)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

FGD4_HUMAN
NC score	0.099082 (rank : 112)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	283	Target Neighborhood Hits	219	Shared Neighborhood Hits	48
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

WASL_MOUSE
NC score	0.097189 (rank : 113)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	283	Target Neighborhood Hits	339	Shared Neighborhood Hits	80
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

NCOA6_HUMAN
NC score	0.096769 (rank : 114)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	283	Target Neighborhood Hits	1202	Shared Neighborhood Hits	112
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

DYN3_HUMAN
NC score	0.096481 (rank : 115)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	283	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

IQEC1_MOUSE
NC score	0.096427 (rank : 116)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	283	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

PKHA3_HUMAN
NC score	0.096303 (rank : 117)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	283	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

CEND3_MOUSE
NC score	0.096004 (rank : 118)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	283	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

OGFR_HUMAN
NC score	0.095291 (rank : 119)	θ value	0.0193708 (rank : 39)
Query Neighborhood Hits	283	Target Neighborhood Hits	1582	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

FGD2_MOUSE
NC score	0.095018 (rank : 120)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	283	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

DGKD_HUMAN
NC score	0.093773 (rank : 121)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	283	Target Neighborhood Hits	231	Shared Neighborhood Hits	32
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

MTMRD_HUMAN
NC score	0.093570 (rank : 122)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	283	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

RIMB1_HUMAN
NC score	0.093486 (rank : 123)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	283	Target Neighborhood Hits	1479	Shared Neighborhood Hits	102
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CT151_HUMAN
NC score	0.091228 (rank : 124)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	283	Target Neighborhood Hits	382	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

FGD2_HUMAN
NC score	0.090702 (rank : 125)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	283	Target Neighborhood Hits	151	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

DIDO1_HUMAN
NC score	0.089902 (rank : 126)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	283	Target Neighborhood Hits	960	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PCLO_MOUSE
NC score	0.089682 (rank : 127)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	283	Target Neighborhood Hits	2275	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRP5_HUMAN
NC score	0.089531 (rank : 128)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	283	Target Neighborhood Hits	108	Shared Neighborhood Hits	30
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

CENA2_MOUSE
NC score	0.089407 (rank : 129)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	283	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

PRRT3_HUMAN
NC score	0.089180 (rank : 130)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	283	Target Neighborhood Hits	998	Shared Neighborhood Hits	95
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

FA47A_HUMAN
NC score	0.088986 (rank : 131)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	283	Target Neighborhood Hits	451	Shared Neighborhood Hits	52
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

DOC10_HUMAN
NC score	0.088553 (rank : 132)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	283	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

MUC7_HUMAN
NC score	0.087505 (rank : 133)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	283	Target Neighborhood Hits	538	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

CAPS2_MOUSE
NC score	0.087434 (rank : 134)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	283	Target Neighborhood Hits	78	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

SMR3A_HUMAN
NC score	0.087395 (rank : 135)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	283	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

WASL_HUMAN
NC score	0.087391 (rank : 136)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	283	Target Neighborhood Hits	312	Shared Neighborhood Hits	75
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PRR12_HUMAN
NC score	0.086985 (rank : 137)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	283	Target Neighborhood Hits	460	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRPE_HUMAN
NC score	0.086616 (rank : 138)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	283	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

NPBL_MOUSE
NC score	0.085911 (rank : 139)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	283	Target Neighborhood Hits	1041	Shared Neighborhood Hits	68
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SRRM2_MOUSE
NC score	0.084520 (rank : 140)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	283	Target Neighborhood Hits	1470	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

IASPP_MOUSE
NC score	0.083272 (rank : 141)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	283	Target Neighborhood Hits	1024	Shared Neighborhood Hits	89
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CJ078_MOUSE
NC score	0.082616 (rank : 142)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	283	Target Neighborhood Hits	559	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

DGKK_HUMAN
NC score	0.082340 (rank : 143)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	283	Target Neighborhood Hits	378	Shared Neighborhood Hits	77
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

CAPS1_MOUSE
NC score	0.082335 (rank : 144)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	283	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

FGD3_HUMAN
NC score	0.081958 (rank : 145)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	283	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

CAPS1_HUMAN
NC score	0.081930 (rank : 146)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	283	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

NFH_MOUSE
NC score	0.080742 (rank : 147)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	283	Target Neighborhood Hits	2247	Shared Neighborhood Hits	154
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CAPS2_HUMAN
NC score	0.080691 (rank : 148)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	283	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

RIMB1_MOUSE
NC score	0.079672 (rank : 149)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	283	Target Neighborhood Hits	1376	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

DYN1_HUMAN
NC score	0.078940 (rank : 150)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	283	Target Neighborhood Hits	216	Shared Neighborhood Hits	70
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

PRG4_HUMAN
NC score	0.078813 (rank : 151)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	283	Target Neighborhood Hits	764	Shared Neighborhood Hits	85
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WIRE_MOUSE
NC score	0.078768 (rank : 152)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	283	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

TARSH_HUMAN
NC score	0.078725 (rank : 153)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	283	Target Neighborhood Hits	768	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

NCOA6_MOUSE
NC score	0.078274 (rank : 154)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	283	Target Neighborhood Hits	1076	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BAT2_MOUSE
NC score	0.078066 (rank : 155)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	283	Target Neighborhood Hits	947	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RAPH1_HUMAN
NC score	0.077800 (rank : 156)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	283	Target Neighborhood Hits	593	Shared Neighborhood Hits	103
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PRPC_HUMAN
NC score	0.077205 (rank : 157)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	283	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

K1914_HUMAN
NC score	0.077131 (rank : 158)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	283	Target Neighborhood Hits	255	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

CRSP7_HUMAN
NC score	0.076552 (rank : 159)	θ value	0.0431538 (rank : 47)
Query Neighborhood Hits	283	Target Neighborhood Hits	247	Shared Neighborhood Hits	21
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CN032_HUMAN
NC score	0.075981 (rank : 160)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	283	Target Neighborhood Hits	267	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

SFPQ_HUMAN
NC score	0.075492 (rank : 161)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	283	Target Neighborhood Hits	986	Shared Neighborhood Hits	111
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CK024_HUMAN
NC score	0.075215 (rank : 162)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	283	Target Neighborhood Hits	408	Shared Neighborhood Hits	56
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

WIRE_HUMAN
NC score	0.074315 (rank : 163)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	283	Target Neighborhood Hits	329	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

MLL2_HUMAN
NC score	0.074256 (rank : 164)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	283	Target Neighborhood Hits	1788	Shared Neighborhood Hits	142
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TAF4_HUMAN
NC score	0.073938 (rank : 165)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	283	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

RASA1_HUMAN
NC score	0.073165 (rank : 166)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	283	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RGS3_MOUSE
NC score	0.072787 (rank : 167)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	283	Target Neighborhood Hits	1621	Shared Neighborhood Hits	123
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DYN1_MOUSE
NC score	0.072674 (rank : 168)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	283	Target Neighborhood Hits	168	Shared Neighborhood Hits	56
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

IASPP_HUMAN
NC score	0.072166 (rank : 169)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	283	Target Neighborhood Hits	688	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

DDFL1_HUMAN
NC score	0.071386 (rank : 170)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	283	Target Neighborhood Hits	353	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

MBB1A_HUMAN
NC score	0.071346 (rank : 171)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	283	Target Neighborhood Hits	665	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

TBCD2_HUMAN
NC score	0.070856 (rank : 172)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	283	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

SYN1_HUMAN
NC score	0.070147 (rank : 173)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	283	Target Neighborhood Hits	419	Shared Neighborhood Hits	87
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

OSBL9_HUMAN
NC score	0.069898 (rank : 174)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	283	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

ENAH_MOUSE
NC score	0.069769 (rank : 175)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	283	Target Neighborhood Hits	919	Shared Neighborhood Hits	107
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ATN1_HUMAN
NC score	0.069726 (rank : 176)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	283	Target Neighborhood Hits	676	Shared Neighborhood Hits	84
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

WBS14_HUMAN
NC score	0.069526 (rank : 177)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	283	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

NIPBL_HUMAN
NC score	0.069474 (rank : 178)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	283	Target Neighborhood Hits	1311	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WBP11_HUMAN
NC score	0.069297 (rank : 179)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	283	Target Neighborhood Hits	354	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

SFPQ_MOUSE
NC score	0.069038 (rank : 180)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	283	Target Neighborhood Hits	958	Shared Neighborhood Hits	106
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SGIP1_HUMAN
NC score	0.068846 (rank : 181)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	283	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

DDEF1_MOUSE
NC score	0.068698 (rank : 182)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	283	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

MDC1_HUMAN
NC score	0.068674 (rank : 183)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	283	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

K1914_MOUSE
NC score	0.068341 (rank : 184)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	283	Target Neighborhood Hits	216	Shared Neighborhood Hits	38
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

BAT2_HUMAN
NC score	0.068233 (rank : 185)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	283	Target Neighborhood Hits	931	Shared Neighborhood Hits	106
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_MOUSE
NC score	0.068226 (rank : 186)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	283	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CO039_MOUSE
NC score	0.067933 (rank : 187)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	283	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

ARI1A_HUMAN
NC score	0.067338 (rank : 188)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	283	Target Neighborhood Hits	787	Shared Neighborhood Hits	85
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NACAM_MOUSE
NC score	0.067323 (rank : 189)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	283	Target Neighborhood Hits	1866	Shared Neighborhood Hits	126
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BCR_HUMAN
NC score	0.066950 (rank : 190)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	283	Target Neighborhood Hits	204	Shared Neighborhood Hits	33
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

EP300_HUMAN
NC score	0.066909 (rank : 191)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	283	Target Neighborhood Hits	821	Shared Neighborhood Hits	83
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CROCC_HUMAN
NC score	0.066877 (rank : 192)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	283	Target Neighborhood Hits	1409	Shared Neighborhood Hits	86
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

K1802_MOUSE
NC score	0.066341 (rank : 193)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	283	Target Neighborhood Hits	1596	Shared Neighborhood Hits	109
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ABR_HUMAN
NC score	0.066309 (rank : 194)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	283	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

GOGA5_MOUSE
NC score	0.066255 (rank : 195)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	283	Target Neighborhood Hits	1434	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

DDEF2_MOUSE
NC score	0.065972 (rank : 196)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	283	Target Neighborhood Hits	625	Shared Neighborhood Hits	71
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SYNJ1_HUMAN
NC score	0.065777 (rank : 197)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	283	Target Neighborhood Hits	498	Shared Neighborhood Hits	85
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ALEX_MOUSE
NC score	0.065654 (rank : 198)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	283	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

NFH_HUMAN
NC score	0.065317 (rank : 199)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	283	Target Neighborhood Hits	1242	Shared Neighborhood Hits	102
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DDFL1_MOUSE
NC score	0.065145 (rank : 200)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	283	Target Neighborhood Hits	324	Shared Neighborhood Hits	32
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

PKHF2_MOUSE
NC score	0.065140 (rank : 201)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	283	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

BASP_MOUSE
NC score	0.065119 (rank : 202)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	283	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SAPS1_HUMAN
NC score	0.065060 (rank : 203)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	283	Target Neighborhood Hits	704	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

GSCR1_HUMAN
NC score	0.064935 (rank : 204)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	283	Target Neighborhood Hits	674	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SC24C_HUMAN
NC score	0.064518 (rank : 205)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	283	Target Neighborhood Hits	662	Shared Neighborhood Hits	59
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

WBP11_MOUSE
NC score	0.064444 (rank : 206)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	283	Target Neighborhood Hits	362	Shared Neighborhood Hits	65
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

DDEF2_HUMAN
NC score	0.063965 (rank : 207)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	283	Target Neighborhood Hits	599	Shared Neighborhood Hits	73
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SET1A_HUMAN
NC score	0.063934 (rank : 208)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	283	Target Neighborhood Hits	690	Shared Neighborhood Hits	86
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

FYCO1_HUMAN
NC score	0.063511 (rank : 209)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	283	Target Neighborhood Hits	1149	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

RERE_MOUSE
NC score	0.063487 (rank : 210)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	283	Target Neighborhood Hits	785	Shared Neighborhood Hits	97
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PRG4_MOUSE
NC score	0.063272 (rank : 211)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	283	Target Neighborhood Hits	624	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCQAP_HUMAN
NC score	0.062983 (rank : 212)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	283	Target Neighborhood Hits	549	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PKHF2_HUMAN
NC score	0.062957 (rank : 213)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	283	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

FYCO1_MOUSE
NC score	0.062947 (rank : 214)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	283	Target Neighborhood Hits	1059	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

MAGE1_HUMAN
NC score	0.062834 (rank : 215)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	283	Target Neighborhood Hits	1389	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP1A_HUMAN
NC score	0.062518 (rank : 216)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	283	Target Neighborhood Hits	1626	Shared Neighborhood Hits	113
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TCGAP_HUMAN
NC score	0.062492 (rank : 217)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	283	Target Neighborhood Hits	872	Shared Neighborhood Hits	79
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MLL3_HUMAN
NC score	0.062446 (rank : 218)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	283	Target Neighborhood Hits	1644	Shared Neighborhood Hits	123
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ARHGF_HUMAN
NC score	0.062338 (rank : 219)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	283	Target Neighborhood Hits	214	Shared Neighborhood Hits	60
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

SON_HUMAN
NC score	0.062260 (rank : 220)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	283	Target Neighborhood Hits	1568	Shared Neighborhood Hits	111
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

AB1IP_HUMAN
NC score	0.062110 (rank : 221)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	283	Target Neighborhood Hits	213	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

CS016_HUMAN
NC score	0.061998 (rank : 222)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	283	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

RASA2_MOUSE
NC score	0.061770 (rank : 223)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	283	Target Neighborhood Hits	159	Shared Neighborhood Hits	38
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

MTMR5_HUMAN
NC score	0.061666 (rank : 224)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	283	Target Neighborhood Hits	141	Shared Neighborhood Hits	36
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

BASP_HUMAN
NC score	0.061607 (rank : 225)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	283	Target Neighborhood Hits	321	Shared Neighborhood Hits	46
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

LRC56_HUMAN
NC score	0.060968 (rank : 226)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	283	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

BAT3_HUMAN
NC score	0.060579 (rank : 227)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	283	Target Neighborhood Hits	490	Shared Neighborhood Hits	54
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

PKHF1_MOUSE
NC score	0.060348 (rank : 228)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	283	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF1_HUMAN
NC score	0.060182 (rank : 229)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

RASA3_HUMAN
NC score	0.059671 (rank : 230)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	283	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

3BP1_HUMAN
NC score	0.059657 (rank : 231)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	283	Target Neighborhood Hits	376	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BAZ2A_MOUSE
NC score	0.059296 (rank : 232)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	283	Target Neighborhood Hits	744	Shared Neighborhood Hits	66
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

GGN_HUMAN
NC score	0.059237 (rank : 233)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	283	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

RUFY2_HUMAN
NC score	0.059214 (rank : 234)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	283	Target Neighborhood Hits	1208	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MILK1_MOUSE
NC score	0.059064 (rank : 235)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	283	Target Neighborhood Hits	788	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SF3B1_HUMAN
NC score	0.059039 (rank : 236)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	283	Target Neighborhood Hits	341	Shared Neighborhood Hits	40
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.059028 (rank : 237)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	283	Target Neighborhood Hits	352	Shared Neighborhood Hits	41
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

MLL3_MOUSE
NC score	0.058957 (rank : 238)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	283	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RUFY2_MOUSE
NC score	0.058956 (rank : 239)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	283	Target Neighborhood Hits	820	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

GGN_MOUSE
NC score	0.058357 (rank : 240)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	283	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CBP_MOUSE
NC score	0.058284 (rank : 241)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	283	Target Neighborhood Hits	1051	Shared Neighborhood Hits	90
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MDC1_MOUSE
NC score	0.058071 (rank : 242)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	283	Target Neighborhood Hits	998	Shared Neighborhood Hits	83
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PYGO2_HUMAN
NC score	0.058030 (rank : 243)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	283	Target Neighborhood Hits	189	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RERE_HUMAN
NC score	0.057715 (rank : 244)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	283	Target Neighborhood Hits	779	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

WBS14_MOUSE
NC score	0.057520 (rank : 245)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	283	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

SYN1_MOUSE
NC score	0.057191 (rank : 246)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	283	Target Neighborhood Hits	363	Shared Neighborhood Hits	74
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

LIPA2_MOUSE
NC score	0.056902 (rank : 247)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	283	Target Neighborhood Hits	1282	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

NCOR2_HUMAN
NC score	0.056773 (rank : 248)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	283	Target Neighborhood Hits	870	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CN032_MOUSE
NC score	0.056759 (rank : 249)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	283	Target Neighborhood Hits	233	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CP250_MOUSE
NC score	0.056575 (rank : 250)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	283	Target Neighborhood Hits	1583	Shared Neighborhood Hits	82
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GOGA5_HUMAN
NC score	0.056431 (rank : 251)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	283	Target Neighborhood Hits	1168	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SI1L3_HUMAN
NC score	0.056296 (rank : 252)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	283	Target Neighborhood Hits	305	Shared Neighborhood Hits	40
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

MBD6_HUMAN
NC score	0.055923 (rank : 253)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	283	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

K1802_HUMAN
NC score	0.055840 (rank : 254)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	283	Target Neighborhood Hits	1378	Shared Neighborhood Hits	102
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASP_MOUSE
NC score	0.055839 (rank : 255)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	283	Target Neighborhood Hits	223	Shared Neighborhood Hits	54
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

RFIP3_HUMAN
NC score	0.055701 (rank : 256)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	283	Target Neighborhood Hits	1055	Shared Neighborhood Hits	86
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

YLPM1_MOUSE
NC score	0.055381 (rank : 257)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	283	Target Neighborhood Hits	505	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

TPR_HUMAN
NC score	0.055221 (rank : 258)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	283	Target Neighborhood Hits	1921	Shared Neighborhood Hits	89
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ITSN1_MOUSE
NC score	0.054797 (rank : 259)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	283	Target Neighborhood Hits	1669	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PRGC2_MOUSE
NC score	0.054427 (rank : 260)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	283	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PSL1_HUMAN
NC score	0.054239 (rank : 261)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	283	Target Neighborhood Hits	650	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

LCP2_HUMAN
NC score	0.054189 (rank : 262)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	283	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ANK2_HUMAN
NC score	0.054072 (rank : 263)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	283	Target Neighborhood Hits	1615	Shared Neighborhood Hits	117
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TGON2_HUMAN
NC score	0.053920 (rank : 264)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	283	Target Neighborhood Hits	1037	Shared Neighborhood Hits	74
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

NOLC1_HUMAN
NC score	0.053799 (rank : 265)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	283	Target Neighborhood Hits	452	Shared Neighborhood Hits	51
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MLL4_HUMAN
NC score	0.053725 (rank : 266)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	283	Target Neighborhood Hits	722	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ARI1B_HUMAN
NC score	0.053657 (rank : 267)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	283	Target Neighborhood Hits	567	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ASPP1_MOUSE
NC score	0.053565 (rank : 268)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	283	Target Neighborhood Hits	1244	Shared Neighborhood Hits	109
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TRAIP_MOUSE
NC score	0.053518 (rank : 269)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	283	Target Neighborhood Hits	745	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

SYNJ1_MOUSE
NC score	0.053460 (rank : 270)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	283	Target Neighborhood Hits	516	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CCNK_MOUSE
NC score	0.053361 (rank : 271)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	283	Target Neighborhood Hits	350	Shared Neighborhood Hits	67
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

HGS_MOUSE
NC score	0.053272 (rank : 272)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	283	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

SON_MOUSE
NC score	0.052743 (rank : 273)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	283	Target Neighborhood Hits	957	Shared Neighborhood Hits	90
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TRAIP_HUMAN
NC score	0.052720 (rank : 274)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	283	Target Neighborhood Hits	780	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

PCNT_HUMAN
NC score	0.052712 (rank : 275)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	283	Target Neighborhood Hits	1551	Shared Neighborhood Hits	87
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCQAP_MOUSE
NC score	0.052646 (rank : 276)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	283	Target Neighborhood Hits	506	Shared Neighborhood Hits	69
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

GOGB1_HUMAN
NC score	0.052511 (rank : 277)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	283	Target Neighborhood Hits	2297	Shared Neighborhood Hits	106
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

OSB11_MOUSE
NC score	0.052491 (rank : 278)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	283	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

MILK1_HUMAN
NC score	0.052252 (rank : 279)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	283	Target Neighborhood Hits	427	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

BAZ2A_HUMAN
NC score	0.052188 (rank : 280)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	283	Target Neighborhood Hits	780	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

ECT2_MOUSE
NC score	0.052097 (rank : 281)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	283	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

AZI1_HUMAN
NC score	0.052072 (rank : 282)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	283	Target Neighborhood Hits	1000	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

WASF2_MOUSE
NC score	0.052058 (rank : 283)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	283	Target Neighborhood Hits	315	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

SFR15_HUMAN
NC score	0.051980 (rank : 284)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	283	Target Neighborhood Hits	368	Shared Neighborhood Hits	50
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

NCOR2_MOUSE
NC score	0.051915 (rank : 285)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	283	Target Neighborhood Hits	790	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MARCS_MOUSE
NC score	0.051897 (rank : 286)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	283	Target Neighborhood Hits	227	Shared Neighborhood Hits	42
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

OSB11_HUMAN
NC score	0.051868 (rank : 287)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	283	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

RBP1_HUMAN
NC score	0.051750 (rank : 288)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	283	Target Neighborhood Hits	521	Shared Neighborhood Hits	45
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG26_HUMAN
NC score	0.051674 (rank : 289)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	283	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CENG1_MOUSE
NC score	0.051626 (rank : 290)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	283	Target Neighborhood Hits	531	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

MUC1_HUMAN
NC score	0.051495 (rank : 291)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	283	Target Neighborhood Hits	975	Shared Neighborhood Hits	78
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PREX1_HUMAN
NC score	0.051440 (rank : 292)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	283	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

CPSF6_MOUSE
NC score	0.051431 (rank : 293)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	283	Target Neighborhood Hits	356	Shared Neighborhood Hits	56
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

ITSN1_HUMAN
NC score	0.051422 (rank : 294)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	283	Target Neighborhood Hits	1757	Shared Neighborhood Hits	95
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

EEA1_MOUSE
NC score	0.051406 (rank : 295)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	283	Target Neighborhood Hits	1637	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GOGA4_MOUSE
NC score	0.051331 (rank : 296)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	283	Target Neighborhood Hits	1939	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SGIP1_MOUSE
NC score	0.051320 (rank : 297)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	283	Target Neighborhood Hits	180	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

RP1L1_HUMAN
NC score	0.051285 (rank : 298)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	283	Target Neighborhood Hits	1072	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CPSF6_HUMAN
NC score	0.051202 (rank : 299)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	283	Target Neighborhood Hits	359	Shared Neighborhood Hits	56
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

TRIPB_HUMAN
NC score	0.051196 (rank : 300)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	283	Target Neighborhood Hits	1587	Shared Neighborhood Hits	81
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CD2_HUMAN
NC score	0.051158 (rank : 301)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	283	Target Neighborhood Hits	504	Shared Neighborhood Hits	52
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

SMAP1_HUMAN
NC score	0.051092 (rank : 302)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	283	Target Neighborhood Hits	98	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

LIPA1_HUMAN
NC score	0.051085 (rank : 303)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	283	Target Neighborhood Hits	1294	Shared Neighborhood Hits	68
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

CP250_HUMAN
NC score	0.051029 (rank : 304)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	283	Target Neighborhood Hits	1805	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

FMNL_HUMAN
NC score	0.050942 (rank : 305)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	283	Target Neighborhood Hits	529	Shared Neighborhood Hits	91
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

CENPF_HUMAN
NC score	0.050881 (rank : 306)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	283	Target Neighborhood Hits	1932	Shared Neighborhood Hits	89
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

RASA2_HUMAN
NC score	0.050880 (rank : 307)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	283	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

EEA1_HUMAN
NC score	0.050819 (rank : 308)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	283	Target Neighborhood Hits	1796	Shared Neighborhood Hits	85
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

BRD4_MOUSE
NC score	0.050773 (rank : 309)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	283	Target Neighborhood Hits	845	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

WASP_HUMAN
NC score	0.050754 (rank : 310)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	283	Target Neighborhood Hits	195	Shared Neighborhood Hits	52
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

NIN_HUMAN
NC score	0.050734 (rank : 311)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	283	Target Neighborhood Hits	1416	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RASA3_MOUSE
NC score	0.050710 (rank : 312)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	283	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

TIAM1_HUMAN
NC score	0.050673 (rank : 313)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	283	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

RUFY1_HUMAN
NC score	0.050670 (rank : 314)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	283	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

OSBL3_HUMAN
NC score	0.050587 (rank : 315)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	283	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

DOT1L_HUMAN
NC score	0.050534 (rank : 316)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	283	Target Neighborhood Hits	660	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ASPP2_HUMAN
NC score	0.050487 (rank : 317)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	283	Target Neighborhood Hits	1156	Shared Neighborhood Hits	91
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CRTC1_HUMAN
NC score	0.050439 (rank : 318)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	283	Target Neighborhood Hits	319	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ECT2_HUMAN
NC score	0.050374 (rank : 319)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	283	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

MINT_HUMAN
NC score	0.050242 (rank : 320)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	283	Target Neighborhood Hits	1291	Shared Neighborhood Hits	104
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SC24D_HUMAN
NC score	0.050227 (rank : 321)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	283	Target Neighborhood Hits	173	Shared Neighborhood Hits	34
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SMAP1_MOUSE
NC score	0.050093 (rank : 322)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	283	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SELPL_MOUSE
NC score	0.050013 (rank : 323)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	283	Target Neighborhood Hits	588	Shared Neighborhood Hits	59
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CUTL1_HUMAN
NC score	0.049184 (rank : 324)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	283	Target Neighborhood Hits	1574	Shared Neighborhood Hits	94
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

MUCDL_HUMAN
NC score	0.049127 (rank : 325)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	283	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MD1L1_HUMAN
NC score	0.048418 (rank : 326)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	283	Target Neighborhood Hits	893	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CK037_HUMAN
NC score	0.048120 (rank : 327)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	283	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N53	Gene names	C11orf37
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C11orf37.

PRGC2_HUMAN
NC score	0.047591 (rank : 328)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	283	Target Neighborhood Hits	272	Shared Neighborhood Hits	39
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

LMO7_HUMAN
NC score	0.047413 (rank : 329)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	283	Target Neighborhood Hits	507	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

JPH2_HUMAN
NC score	0.047307 (rank : 330)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	283	Target Neighborhood Hits	639	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ANR15_HUMAN
NC score	0.047182 (rank : 331)	θ value	0.0431538 (rank : 44)
Query Neighborhood Hits	283	Target Neighborhood Hits	478	Shared Neighborhood Hits	35
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ZN414_HUMAN
NC score	0.046624 (rank : 332)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	283	Target Neighborhood Hits	548	Shared Neighborhood Hits	38
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

TXND2_HUMAN
NC score	0.045756 (rank : 333)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	283	Target Neighborhood Hits	793	Shared Neighborhood Hits	57
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

EP15R_HUMAN
NC score	0.045578 (rank : 334)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	283	Target Neighborhood Hits	1083	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ANR26_MOUSE
NC score	0.045553 (rank : 335)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	283	Target Neighborhood Hits	1554	Shared Neighborhood Hits	76
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CYTSA_HUMAN
NC score	0.045041 (rank : 336)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	283	Target Neighborhood Hits	1138	Shared Neighborhood Hits	77
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

LSR_HUMAN
NC score	0.045004 (rank : 337)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	283	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

RGS3_HUMAN
NC score	0.044821 (rank : 338)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	283	Target Neighborhood Hits	1375	Shared Neighborhood Hits	95
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

LUZP1_MOUSE
NC score	0.044395 (rank : 339)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	283	Target Neighborhood Hits	940	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MYO15_HUMAN
NC score	0.044058 (rank : 340)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	283	Target Neighborhood Hits	671	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ATX1_MOUSE
NC score	0.043262 (rank : 341)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	283	Target Neighborhood Hits	264	Shared Neighborhood Hits	28
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

FMN1B_MOUSE
NC score	0.043176 (rank : 342)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	283	Target Neighborhood Hits	447	Shared Neighborhood Hits	64
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

DNMBP_HUMAN
NC score	0.042549 (rank : 343)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	283	Target Neighborhood Hits	413	Shared Neighborhood Hits	30
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

CUTL2_MOUSE
NC score	0.042398 (rank : 344)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	283	Target Neighborhood Hits	771	Shared Neighborhood Hits	66
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ZNHI4_MOUSE
NC score	0.041697 (rank : 345)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	283	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

SPTN2_HUMAN
NC score	0.041387 (rank : 346)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	283	Target Neighborhood Hits	535	Shared Neighborhood Hits	60
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

ANR26_HUMAN
NC score	0.041254 (rank : 347)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	283	Target Neighborhood Hits	1614	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RBNS5_MOUSE
NC score	0.041050 (rank : 348)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	283	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

CJ108_HUMAN
NC score	0.039863 (rank : 349)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	283	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

JADE2_MOUSE
NC score	0.038919 (rank : 350)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	283	Target Neighborhood Hits	560	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K1C16_HUMAN
NC score	0.038538 (rank : 351)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	283	Target Neighborhood Hits	440	Shared Neighborhood Hits	48
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

BPAEA_MOUSE
NC score	0.038423 (rank : 352)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	283	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

XRCC1_MOUSE
NC score	0.038149 (rank : 353)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	283	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

MAGC1_HUMAN
NC score	0.037250 (rank : 354)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	283	Target Neighborhood Hits	431	Shared Neighborhood Hits	56
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PDZD2_HUMAN
NC score	0.036666 (rank : 355)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	283	Target Neighborhood Hits	772	Shared Neighborhood Hits	69
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PHF3_HUMAN
NC score	0.035119 (rank : 356)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	283	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

DOK7_MOUSE
NC score	0.035118 (rank : 357)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	283	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

CT128_HUMAN
NC score	0.034880 (rank : 358)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	283	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

CSF1_HUMAN
NC score	0.034678 (rank : 359)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	283	Target Neighborhood Hits	258	Shared Neighborhood Hits	32
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

K2C1B_HUMAN
NC score	0.034666 (rank : 360)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	283	Target Neighborhood Hits	542	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

NRX2B_HUMAN
NC score	0.034530 (rank : 361)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	283	Target Neighborhood Hits	481	Shared Neighborhood Hits	49
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PTPR2_MOUSE
NC score	0.034378 (rank : 362)	θ value	0.00134147 (rank : 22)
Query Neighborhood Hits	283	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PERI_MOUSE
NC score	0.034062 (rank : 363)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	283	Target Neighborhood Hits	502	Shared Neighborhood Hits	44
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

ATX1_HUMAN
NC score	0.034059 (rank : 364)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	283	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

DEND_HUMAN
NC score	0.034013 (rank : 365)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	283	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

CTTB2_HUMAN
NC score	0.033954 (rank : 366)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	283	Target Neighborhood Hits	1061	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

RP3A_MOUSE
NC score	0.032908 (rank : 367)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	283	Target Neighborhood Hits	510	Shared Neighborhood Hits	57
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

USF2_MOUSE
NC score	0.032864 (rank : 368)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	283	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

CCD71_HUMAN
NC score	0.032857 (rank : 369)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	283	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IV32, Q6IPE2, Q9H8H4, Q9H9F1	Gene names	CCDC71
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 71.

RUSC2_MOUSE
NC score	0.032456 (rank : 370)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	283	Target Neighborhood Hits	305	Shared Neighborhood Hits	42
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

ANR35_HUMAN
NC score	0.032394 (rank : 371)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	283	Target Neighborhood Hits	784	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

UBP42_HUMAN
NC score	0.032214 (rank : 372)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	283	Target Neighborhood Hits	445	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

TCP10_HUMAN
NC score	0.032196 (rank : 373)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	283	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

PERI_HUMAN
NC score	0.031942 (rank : 374)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	283	Target Neighborhood Hits	506	Shared Neighborhood Hits	45
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

CTRO_MOUSE
NC score	0.031310 (rank : 375)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	283	Target Neighborhood Hits	2344	Shared Neighborhood Hits	97
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SOX13_HUMAN
NC score	0.031131 (rank : 376)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	283	Target Neighborhood Hits	464	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ZN414_MOUSE
NC score	0.030571 (rank : 377)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	283	Target Neighborhood Hits	473	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

USF2_HUMAN
NC score	0.030369 (rank : 378)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	283	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

RTN1_MOUSE
NC score	0.030247 (rank : 379)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	283	Target Neighborhood Hits	189	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

LPP_HUMAN
NC score	0.029978 (rank : 380)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	283	Target Neighborhood Hits	775	Shared Neighborhood Hits	69
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

KRHB6_MOUSE
NC score	0.029827 (rank : 381)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	283	Target Neighborhood Hits	413	Shared Neighborhood Hits	35
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

K1C12_MOUSE
NC score	0.029609 (rank : 382)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	283	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

CTRO_HUMAN
NC score	0.029211 (rank : 383)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	283	Target Neighborhood Hits	2092	Shared Neighborhood Hits	91
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

INVS_HUMAN
NC score	0.028534 (rank : 384)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	283	Target Neighborhood Hits	455	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

K1C16_MOUSE
NC score	0.028216 (rank : 385)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	283	Target Neighborhood Hits	444	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z2K1	Gene names	Krt16, Krt1-16
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

SEPT9_HUMAN
NC score	0.027908 (rank : 386)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	283	Target Neighborhood Hits	706	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

HCLS1_MOUSE
NC score	0.027525 (rank : 387)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	283	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

JIP1_MOUSE
NC score	0.027510 (rank : 388)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	283	Target Neighborhood Hits	259	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ZDHC5_MOUSE
NC score	0.027148 (rank : 389)	θ value	0.163984 (rank : 74)
Query Neighborhood Hits	283	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

SOX13_MOUSE
NC score	0.026477 (rank : 390)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	283	Target Neighborhood Hits	495	Shared Neighborhood Hits	46
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

PHLPP_HUMAN
NC score	0.026039 (rank : 391)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	283	Target Neighborhood Hits	604	Shared Neighborhood Hits	46
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SIA7A_HUMAN
NC score	0.025782 (rank : 392)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	283	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

GRIP2_HUMAN
NC score	0.024236 (rank : 393)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	283	Target Neighborhood Hits	256	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

SART3_MOUSE
NC score	0.023138 (rank : 394)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	283	Target Neighborhood Hits	341	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

CHD9_HUMAN
NC score	0.022674 (rank : 395)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	283	Target Neighborhood Hits	343	Shared Neighborhood Hits	19
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

NCOR1_HUMAN
NC score	0.022511 (rank : 396)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	283	Target Neighborhood Hits	577	Shared Neighborhood Hits	44
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

SPEG_MOUSE
NC score	0.022493 (rank : 397)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	283	Target Neighborhood Hits	1959	Shared Neighborhood Hits	109
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CHD9_MOUSE
NC score	0.022270 (rank : 398)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	283	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

NRX2A_HUMAN
NC score	0.022267 (rank : 399)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	283	Target Neighborhood Hits	614	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

K1C19_HUMAN
NC score	0.022192 (rank : 400)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	283	Target Neighborhood Hits	320	Shared Neighborhood Hits	32
SwissProt Accessions	P08727, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4	Gene names	KRT19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

MRCKB_MOUSE
NC score	0.022176 (rank : 401)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	283	Target Neighborhood Hits	2180	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

DOK2_MOUSE
NC score	0.021854 (rank : 402)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	283	Target Neighborhood Hits	244	Shared Neighborhood Hits	25
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

PHLPP_MOUSE
NC score	0.021622 (rank : 403)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	283	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

SART3_HUMAN
NC score	0.021560 (rank : 404)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	283	Target Neighborhood Hits	301	Shared Neighborhood Hits	9
SwissProt Accessions	Q15020, Q58F06, Q8IUS1, Q96J95	Gene names	SART3, KIAA0156, TIP110
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (hSART-3) (Tat-interacting protein of 110 kDa) (Tip110).

MEGF9_MOUSE
NC score	0.020668 (rank : 405)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	283	Target Neighborhood Hits	896	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

AHTF1_MOUSE
NC score	0.020517 (rank : 406)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	283	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CAC1G_HUMAN
NC score	0.020147 (rank : 407)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	283	Target Neighborhood Hits	587	Shared Neighborhood Hits	57
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

ABI1_HUMAN
NC score	0.019641 (rank : 408)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	283	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

GRIP1_HUMAN
NC score	0.019538 (rank : 409)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	283	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SESN2_HUMAN
NC score	0.019313 (rank : 410)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	283	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

TFE3_HUMAN
NC score	0.019193 (rank : 411)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	283	Target Neighborhood Hits	190	Shared Neighborhood Hits	15
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

FOG1_HUMAN
NC score	0.018662 (rank : 412)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	283	Target Neighborhood Hits	981	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

K0179_HUMAN
NC score	0.018307 (rank : 413)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	283	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q14684, Q8TBZ4	Gene names	KIAA0179
Domain Architecture
Description	Protein KIAA0179.

SPEG_HUMAN
NC score	0.017990 (rank : 414)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	283	Target Neighborhood Hits	1762	Shared Neighborhood Hits	104
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MAST4_HUMAN
NC score	0.017654 (rank : 415)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	283	Target Neighborhood Hits	1804	Shared Neighborhood Hits	101
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

FOLC_HUMAN
NC score	0.017187 (rank : 416)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	283	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

SEM6C_MOUSE
NC score	0.017142 (rank : 417)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	283	Target Neighborhood Hits	352	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

I17RA_MOUSE
NC score	0.016905 (rank : 418)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	283	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

STAT6_HUMAN
NC score	0.015674 (rank : 419)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	283	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

KCNQ4_HUMAN
NC score	0.015508 (rank : 420)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	283	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

NOS3_MOUSE
NC score	0.015467 (rank : 421)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	283	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

PDLI7_HUMAN
NC score	0.014970 (rank : 422)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	283	Target Neighborhood Hits	547	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

FOG1_MOUSE
NC score	0.014310 (rank : 423)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	283	Target Neighborhood Hits	1237	Shared Neighborhood Hits	77
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

OBSCN_HUMAN
NC score	0.012981 (rank : 424)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	283	Target Neighborhood Hits	1931	Shared Neighborhood Hits	87
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SORC3_MOUSE
NC score	0.012859 (rank : 425)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	283	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SEM6B_HUMAN
NC score	0.011518 (rank : 426)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	283	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

PCDA2_HUMAN
NC score	0.010664 (rank : 427)	θ value	0.279714 (rank : 84)
Query Neighborhood Hits	283	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

SMAD4_MOUSE
NC score	0.009644 (rank : 428)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	283	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

PDLI4_MOUSE
NC score	0.009406 (rank : 429)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	283	Target Neighborhood Hits	233	Shared Neighborhood Hits	10
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

MMP21_HUMAN
NC score	0.008380 (rank : 430)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	283	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

GLI2_HUMAN
NC score	0.007401 (rank : 431)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	283	Target Neighborhood Hits	971	Shared Neighborhood Hits	37
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ACK1_HUMAN
NC score	0.006879 (rank : 432)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	283	Target Neighborhood Hits	1140	Shared Neighborhood Hits	71
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ULK1_HUMAN
NC score	0.004062 (rank : 433)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	283	Target Neighborhood Hits	1121	Shared Neighborhood Hits	44
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

NVL_MOUSE
NC score	0.003743 (rank : 434)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	283	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

MK15_MOUSE
NC score	0.002024 (rank : 435)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	283	Target Neighborhood Hits	843	Shared Neighborhood Hits	20
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

CADH4_MOUSE
NC score	0.001999 (rank : 436)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	283	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	P39038	Gene names	Cdh4
Domain Architecture
Description	Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD).

ADAM9_MOUSE
NC score	0.001925 (rank : 437)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	283	Target Neighborhood Hits	325	Shared Neighborhood Hits	14
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ZN575_HUMAN
NC score	0.001231 (rank : 438)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	283	Target Neighborhood Hits	739	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ZN575_MOUSE
NC score	-0.000120 (rank : 439)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	283	Target Neighborhood Hits	715	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

EGFR_HUMAN
NC score	-0.001016 (rank : 440)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	283	Target Neighborhood Hits	939	Shared Neighborhood Hits	17
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ZN319_MOUSE
NC score	-0.003343 (rank : 441)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	283	Target Neighborhood Hits	762	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

HKR3_HUMAN
NC score	-0.003350 (rank : 442)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	283	Target Neighborhood Hits	839	Shared Neighborhood Hits	17
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).