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Network neighborhood for query Sequence : NOS3_MOUSE

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NOS3_MOUSE
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOS1_HUMAN
θ value	0 (rank : 1)	NC score	0.905206 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_MOUSE
θ value	0 (rank : 2)	NC score	0.923282 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS2A_HUMAN
θ value	0 (rank : 3)	NC score	0.988307 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

NOS2_MOUSE
θ value	0 (rank : 4)	NC score	0.988832 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NOS3_HUMAN
θ value	0 (rank : 5)	NC score	0.997165 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NCPR_HUMAN
θ value	2.40537e-61 (rank : 7)	NC score	0.872497 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P16435, Q16455, Q8N181, Q9H3M8	Gene names	POR, CYPOR
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

NCPR_MOUSE
θ value	3.47335e-60 (rank : 8)	NC score	0.874013 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P37040	Gene names	Por
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

MTRR_HUMAN
θ value	3.99248e-40 (rank : 9)	NC score	0.864994 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

BAT2_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.033404 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	947	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABL1_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.034813 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

AATM_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.038194 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

WASF2_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.019401 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	315	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

MYRIP_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.018179 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PCLO_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.025289 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ATX2L_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.023563 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

SC24C_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.021777 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	662	Shared Neighborhood Hits	27
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

BAT2_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.027114 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	931	Shared Neighborhood Hits	23
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PKHA4_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.015467 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	283	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

THAP7_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.022721 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

AATM_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.034827 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P00505, Q9BWA3	Gene names	GOT2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

WIRE_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.031024 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

AB1IP_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.011378 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ECM1_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.016816 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	182	Shared Neighborhood Hits	8
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

GLIS1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.002118 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

PRP1_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.019592 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WBP11_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.026401 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WIRE_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.027944 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	329	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CPSF1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.012008 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

MSX3_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.006119 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	330	Shared Neighborhood Hits	3
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

TITIN_HUMAN
θ value	4.03905 (rank : 31)	NC score	-0.000513 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	2923	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WASL_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.011267 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	339	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.023977 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ZN598_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.013210 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	339	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZO1_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.012276 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	453	Shared Neighborhood Hits	11
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ANX11_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.004875 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

CN092_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.009062 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CSKI1_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.005567 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	997	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DBNL_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.007365 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DVL2_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.045704 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

EPS8_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.010165 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

MTMR3_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.005147 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

PRB3_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.017737 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	318	Shared Neighborhood Hits	14
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

TBCD2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.007534 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

AATK_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.003470 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	1243	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CELR3_MOUSE
θ value	6.88961 (rank : 46)	NC score	-0.000240 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	687	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CO4A3_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.002478 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	421	Shared Neighborhood Hits	11
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

LAD1_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.010300 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	441	Shared Neighborhood Hits	10
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MKL1_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.009190 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	667	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SMN_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.011635 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

SYNPO_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.009011 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TAOK2_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.000229 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	1373	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

ATX2L_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.013770 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	443	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BCR_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.003155 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CTDP1_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.008039 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDEF2_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.005373 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	599	Shared Neighborhood Hits	12
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FBLI1_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.006115 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

MILK1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.005808 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	788	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MIRO2_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.003422 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	228	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZN7	Gene names	Rhot2, Arht2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (Ras homolog gene family member T2).

PZP_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.004033 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

THAP7_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.015777 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

UFO_HUMAN
θ value	8.99809 (rank : 62)	NC score	-0.001251 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	981	Shared Neighborhood Hits	5
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

ZYX_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.007980 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

SNTB1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.050908 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.051063 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTB2_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.050112 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	180	Shared Neighborhood Hits	5
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.051316 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

Hits sorted by NC score

NOS3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_HUMAN
NC score	0.997165 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS2_MOUSE
NC score	0.988832 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NOS2A_HUMAN
NC score	0.988307 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

NOS1_MOUSE
NC score	0.923282 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_HUMAN
NC score	0.905206 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NCPR_MOUSE
NC score	0.874013 (rank : 7)	θ value	3.47335e-60 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P37040	Gene names	Por
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

NCPR_HUMAN
NC score	0.872497 (rank : 8)	θ value	2.40537e-61 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P16435, Q16455, Q8N181, Q9H3M8	Gene names	POR, CYPOR
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

MTRR_HUMAN
NC score	0.864994 (rank : 9)	θ value	3.99248e-40 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

SNTB2_MOUSE
NC score	0.051316 (rank : 10)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB1_MOUSE
NC score	0.051063 (rank : 11)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTB1_HUMAN
NC score	0.050908 (rank : 12)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB2_HUMAN
NC score	0.050112 (rank : 13)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	180	Shared Neighborhood Hits	5
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DVL2_HUMAN
NC score	0.045704 (rank : 14)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

AATM_MOUSE
NC score	0.038194 (rank : 15)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

AATM_HUMAN
NC score	0.034827 (rank : 16)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P00505, Q9BWA3	Gene names	GOT2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

CABL1_HUMAN
NC score	0.034813 (rank : 17)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

BAT2_MOUSE
NC score	0.033404 (rank : 18)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	947	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WIRE_MOUSE
NC score	0.031024 (rank : 19)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WIRE_HUMAN
NC score	0.027944 (rank : 20)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	329	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

BAT2_HUMAN
NC score	0.027114 (rank : 21)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	931	Shared Neighborhood Hits	23
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WBP11_HUMAN
NC score	0.026401 (rank : 22)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

PCLO_MOUSE
NC score	0.025289 (rank : 23)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

WBP11_MOUSE
NC score	0.023977 (rank : 24)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ATX2L_MOUSE
NC score	0.023563 (rank : 25)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

THAP7_MOUSE
NC score	0.022721 (rank : 26)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

SC24C_HUMAN
NC score	0.021777 (rank : 27)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	662	Shared Neighborhood Hits	27
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PRP1_HUMAN
NC score	0.019592 (rank : 28)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WASF2_MOUSE
NC score	0.019401 (rank : 29)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	315	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

MYRIP_HUMAN
NC score	0.018179 (rank : 30)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PRB3_HUMAN
NC score	0.017737 (rank : 31)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	318	Shared Neighborhood Hits	14
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

ECM1_HUMAN
NC score	0.016816 (rank : 32)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	182	Shared Neighborhood Hits	8
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

THAP7_HUMAN
NC score	0.015777 (rank : 33)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

PKHA4_HUMAN
NC score	0.015467 (rank : 34)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	283	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

ATX2L_HUMAN
NC score	0.013770 (rank : 35)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	443	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ZN598_HUMAN
NC score	0.013210 (rank : 36)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	339	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZO1_MOUSE
NC score	0.012276 (rank : 37)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	453	Shared Neighborhood Hits	11
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CPSF1_MOUSE
NC score	0.012008 (rank : 38)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

SMN_MOUSE
NC score	0.011635 (rank : 39)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

AB1IP_HUMAN
NC score	0.011378 (rank : 40)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

WASL_MOUSE
NC score	0.011267 (rank : 41)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	339	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

LAD1_HUMAN
NC score	0.010300 (rank : 42)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	441	Shared Neighborhood Hits	10
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

EPS8_MOUSE
NC score	0.010165 (rank : 43)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

MKL1_MOUSE
NC score	0.009190 (rank : 44)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	667	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CN092_MOUSE
NC score	0.009062 (rank : 45)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

SYNPO_HUMAN
NC score	0.009011 (rank : 46)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CTDP1_MOUSE
NC score	0.008039 (rank : 47)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

ZYX_HUMAN
NC score	0.007980 (rank : 48)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

TBCD2_HUMAN
NC score	0.007534 (rank : 49)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

DBNL_HUMAN
NC score	0.007365 (rank : 50)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

MSX3_MOUSE
NC score	0.006119 (rank : 51)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	330	Shared Neighborhood Hits	3
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

FBLI1_MOUSE
NC score	0.006115 (rank : 52)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

MILK1_MOUSE
NC score	0.005808 (rank : 53)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	788	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CSKI1_HUMAN
NC score	0.005567 (rank : 54)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	997	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DDEF2_HUMAN
NC score	0.005373 (rank : 55)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	599	Shared Neighborhood Hits	12
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MTMR3_HUMAN
NC score	0.005147 (rank : 56)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

ANX11_MOUSE
NC score	0.004875 (rank : 57)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

PZP_HUMAN
NC score	0.004033 (rank : 58)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

AATK_HUMAN
NC score	0.003470 (rank : 59)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	1243	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

MIRO2_MOUSE
NC score	0.003422 (rank : 60)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	228	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZN7	Gene names	Rhot2, Arht2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (Ras homolog gene family member T2).

BCR_HUMAN
NC score	0.003155 (rank : 61)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CO4A3_HUMAN
NC score	0.002478 (rank : 62)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	421	Shared Neighborhood Hits	11
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

GLIS1_HUMAN
NC score	0.002118 (rank : 63)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

TAOK2_MOUSE
NC score	0.000229 (rank : 64)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	1373	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

CELR3_MOUSE
NC score	-0.000240 (rank : 65)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	687	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

TITIN_HUMAN
NC score	-0.000513 (rank : 66)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	2923	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UFO_HUMAN
NC score	-0.001251 (rank : 67)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	981	Shared Neighborhood Hits	5
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).