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Network neighborhood for query Sequence : AB1IP_HUMAN

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AB1IP_HUMAN
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AB1IP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	213	Target Neighborhood Hits	213	Shared Neighborhood Hits	213
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
θ value	4.11024e-170 (rank : 2)	NC score	0.951245 (rank : 2)
Query Neighborhood Hits	213	Target Neighborhood Hits	181	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

RAPH1_HUMAN
θ value	7.37397e-111 (rank : 3)	NC score	0.822430 (rank : 3)
Query Neighborhood Hits	213	Target Neighborhood Hits	593	Shared Neighborhood Hits	125
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GRB14_HUMAN
θ value	8.59492e-43 (rank : 4)	NC score	0.693165 (rank : 7)
Query Neighborhood Hits	213	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB10_HUMAN
θ value	5.76516e-39 (rank : 5)	NC score	0.722649 (rank : 5)
Query Neighborhood Hits	213	Target Neighborhood Hits	147	Shared Neighborhood Hits	13
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB14_MOUSE
θ value	9.83387e-39 (rank : 6)	NC score	0.676853 (rank : 9)
Query Neighborhood Hits	213	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB10_MOUSE
θ value	2.19075e-38 (rank : 7)	NC score	0.725188 (rank : 4)
Query Neighborhood Hits	213	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB7_HUMAN
θ value	1.24399e-33 (rank : 8)	NC score	0.700228 (rank : 6)
Query Neighborhood Hits	213	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	1.6813e-30 (rank : 9)	NC score	0.681209 (rank : 8)
Query Neighborhood Hits	213	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

CEL_HUMAN
θ value	2.36244e-08 (rank : 10)	NC score	0.111278 (rank : 42)
Query Neighborhood Hits	213	Target Neighborhood Hits	896	Shared Neighborhood Hits	72
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

MUC1_HUMAN
θ value	4.92598e-06 (rank : 11)	NC score	0.102679 (rank : 64)
Query Neighborhood Hits	213	Target Neighborhood Hits	975	Shared Neighborhood Hits	70
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RGS3_MOUSE
θ value	5.44631e-05 (rank : 12)	NC score	0.123541 (rank : 27)
Query Neighborhood Hits	213	Target Neighborhood Hits	1621	Shared Neighborhood Hits	103
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SON_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.112869 (rank : 41)
Query Neighborhood Hits	213	Target Neighborhood Hits	1568	Shared Neighborhood Hits	103
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TCGAP_HUMAN
θ value	0.00134147 (rank : 14)	NC score	0.081252 (rank : 124)
Query Neighborhood Hits	213	Target Neighborhood Hits	872	Shared Neighborhood Hits	71
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RGS3_HUMAN
θ value	0.00175202 (rank : 15)	NC score	0.099176 (rank : 71)
Query Neighborhood Hits	213	Target Neighborhood Hits	1375	Shared Neighborhood Hits	84
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TXND2_HUMAN
θ value	0.00228821 (rank : 16)	NC score	0.094570 (rank : 85)
Query Neighborhood Hits	213	Target Neighborhood Hits	793	Shared Neighborhood Hits	45
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CEND1_HUMAN
θ value	0.00509761 (rank : 17)	NC score	0.098530 (rank : 74)
Query Neighborhood Hits	213	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

SEPT9_HUMAN
θ value	0.00509761 (rank : 18)	NC score	0.058591 (rank : 270)
Query Neighborhood Hits	213	Target Neighborhood Hits	706	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

NACAM_MOUSE
θ value	0.00665767 (rank : 19)	NC score	0.128565 (rank : 23)
Query Neighborhood Hits	213	Target Neighborhood Hits	1866	Shared Neighborhood Hits	109
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.095061 (rank : 84)
Query Neighborhood Hits	213	Target Neighborhood Hits	1582	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MAGE1_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.095168 (rank : 83)
Query Neighborhood Hits	213	Target Neighborhood Hits	1389	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ACK1_HUMAN
θ value	0.0330416 (rank : 22)	NC score	0.029818 (rank : 372)
Query Neighborhood Hits	213	Target Neighborhood Hits	1140	Shared Neighborhood Hits	76
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

GA2L2_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.086140 (rank : 109)
Query Neighborhood Hits	213	Target Neighborhood Hits	395	Shared Neighborhood Hits	43
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

BLNK_MOUSE
θ value	0.0563607 (rank : 24)	NC score	0.090302 (rank : 95)
Query Neighborhood Hits	213	Target Neighborhood Hits	296	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CEND1_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.074948 (rank : 172)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

BCL9_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.103864 (rank : 62)
Query Neighborhood Hits	213	Target Neighborhood Hits	1008	Shared Neighborhood Hits	80
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PRRT3_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.107670 (rank : 53)
Query Neighborhood Hits	213	Target Neighborhood Hits	998	Shared Neighborhood Hits	81
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CYH3_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.091069 (rank : 91)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

MAP1A_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.057849 (rank : 274)
Query Neighborhood Hits	213	Target Neighborhood Hits	1626	Shared Neighborhood Hits	80
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MTSS1_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.078643 (rank : 138)
Query Neighborhood Hits	213	Target Neighborhood Hits	504	Shared Neighborhood Hits	37
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CYH3_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.095630 (rank : 80)
Query Neighborhood Hits	213	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

PCLO_MOUSE
θ value	0.125558 (rank : 32)	NC score	0.089240 (rank : 100)
Query Neighborhood Hits	213	Target Neighborhood Hits	2275	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZN687_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.034072 (rank : 363)
Query Neighborhood Hits	213	Target Neighborhood Hits	1244	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CTDP1_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.064463 (rank : 240)
Query Neighborhood Hits	213	Target Neighborhood Hits	416	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

GAB1_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.082727 (rank : 117)
Query Neighborhood Hits	213	Target Neighborhood Hits	233	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

JADE2_MOUSE
θ value	0.163984 (rank : 36)	NC score	0.050953 (rank : 334)
Query Neighborhood Hits	213	Target Neighborhood Hits	560	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K1802_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.082463 (rank : 118)
Query Neighborhood Hits	213	Target Neighborhood Hits	1596	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL3_HUMAN
θ value	0.163984 (rank : 38)	NC score	0.087311 (rank : 106)
Query Neighborhood Hits	213	Target Neighborhood Hits	1644	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ECM1_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.075553 (rank : 160)
Query Neighborhood Hits	213	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

NCOR2_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.064251 (rank : 243)
Query Neighborhood Hits	213	Target Neighborhood Hits	790	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CEND2_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.058461 (rank : 271)
Query Neighborhood Hits	213	Target Neighborhood Hits	166	Shared Neighborhood Hits	23
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CYH1_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.095613 (rank : 81)
Query Neighborhood Hits	213	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	0.279714 (rank : 43)	NC score	0.095938 (rank : 79)
Query Neighborhood Hits	213	Target Neighborhood Hits	176	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.093821 (rank : 88)
Query Neighborhood Hits	213	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

EFS_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.059396 (rank : 264)
Query Neighborhood Hits	213	Target Neighborhood Hits	389	Shared Neighborhood Hits	34
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

FA47B_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.116440 (rank : 37)
Query Neighborhood Hits	213	Target Neighborhood Hits	431	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GAK5_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.075598 (rank : 158)
Query Neighborhood Hits	213	Target Neighborhood Hits	429	Shared Neighborhood Hits	38
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LCP2_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.128048 (rank : 24)
Query Neighborhood Hits	213	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

RC3H1_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.051641 (rank : 330)
Query Neighborhood Hits	213	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TAU_HUMAN
θ value	0.279714 (rank : 50)	NC score	0.073428 (rank : 183)
Query Neighborhood Hits	213	Target Neighborhood Hits	448	Shared Neighborhood Hits	52
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

3BP2_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.088021 (rank : 103)
Query Neighborhood Hits	213	Target Neighborhood Hits	296	Shared Neighborhood Hits	51
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACK1_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.025341 (rank : 380)
Query Neighborhood Hits	213	Target Neighborhood Hits	1080	Shared Neighborhood Hits	65
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

FOXJ2_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.029355 (rank : 374)
Query Neighborhood Hits	213	Target Neighborhood Hits	239	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GAK11_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.074736 (rank : 177)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	38
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.072139 (rank : 191)
Query Neighborhood Hits	213	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.074048 (rank : 179)
Query Neighborhood Hits	213	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.074776 (rank : 174)
Query Neighborhood Hits	213	Target Neighborhood Hits	415	Shared Neighborhood Hits	38
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NUMBL_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.065823 (rank : 228)
Query Neighborhood Hits	213	Target Neighborhood Hits	394	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

RTKN_HUMAN
θ value	0.365318 (rank : 59)	NC score	0.070373 (rank : 204)
Query Neighborhood Hits	213	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

URP2_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.044019 (rank : 347)
Query Neighborhood Hits	213	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

CD248_HUMAN
θ value	0.47712 (rank : 61)	NC score	0.049385 (rank : 341)
Query Neighborhood Hits	213	Target Neighborhood Hits	679	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CYH2_MOUSE
θ value	0.47712 (rank : 62)	NC score	0.092849 (rank : 90)
Query Neighborhood Hits	213	Target Neighborhood Hits	171	Shared Neighborhood Hits	27
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

JPH2_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.052877 (rank : 313)
Query Neighborhood Hits	213	Target Neighborhood Hits	639	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SSBP4_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.056864 (rank : 281)
Query Neighborhood Hits	213	Target Neighborhood Hits	753	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ULK1_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.008934 (rank : 420)
Query Neighborhood Hits	213	Target Neighborhood Hits	1214	Shared Neighborhood Hits	40
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

F120C_MOUSE
θ value	0.62314 (rank : 66)	NC score	0.052625 (rank : 316)
Query Neighborhood Hits	213	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

FGFP3_HUMAN
θ value	0.62314 (rank : 67)	NC score	0.049831 (rank : 340)
Query Neighborhood Hits	213	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

MLL3_MOUSE
θ value	0.62314 (rank : 68)	NC score	0.075358 (rank : 163)
Query Neighborhood Hits	213	Target Neighborhood Hits	1399	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NFH_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.065242 (rank : 232)
Query Neighborhood Hits	213	Target Neighborhood Hits	2247	Shared Neighborhood Hits	98
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

YTHD2_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.025071 (rank : 381)
Query Neighborhood Hits	213	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

BAG3_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.096324 (rank : 78)
Query Neighborhood Hits	213	Target Neighborhood Hits	513	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

COX10_MOUSE
θ value	0.813845 (rank : 72)	NC score	0.033457 (rank : 365)
Query Neighborhood Hits	213	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

GNAS1_MOUSE
θ value	0.813845 (rank : 73)	NC score	0.048593 (rank : 342)
Query Neighborhood Hits	213	Target Neighborhood Hits	651	Shared Neighborhood Hits	56
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

KLF17_HUMAN
θ value	0.813845 (rank : 74)	NC score	0.010842 (rank : 416)
Query Neighborhood Hits	213	Target Neighborhood Hits	882	Shared Neighborhood Hits	34
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

MISS_MOUSE
θ value	0.813845 (rank : 75)	NC score	0.110686 (rank : 46)
Query Neighborhood Hits	213	Target Neighborhood Hits	444	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MTSS1_MOUSE
θ value	0.813845 (rank : 76)	NC score	0.069141 (rank : 208)
Query Neighborhood Hits	213	Target Neighborhood Hits	592	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUCDL_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.071539 (rank : 195)
Query Neighborhood Hits	213	Target Neighborhood Hits	777	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RBBP6_HUMAN
θ value	0.813845 (rank : 78)	NC score	0.040359 (rank : 351)
Query Neighborhood Hits	213	Target Neighborhood Hits	1135	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ANTOL_MOUSE
θ value	1.06291 (rank : 79)	NC score	0.034770 (rank : 361)
Query Neighborhood Hits	213	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8N6	Gene names
Domain Architecture	No domain graphic available
Description	Antolefinin (Antolefinine).

GAK1_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.065458 (rank : 231)
Query Neighborhood Hits	213	Target Neighborhood Hits	268	Shared Neighborhood Hits	25
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PSL1_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.064001 (rank : 244)
Query Neighborhood Hits	213	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RX_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.009265 (rank : 418)
Query Neighborhood Hits	213	Target Neighborhood Hits	429	Shared Neighborhood Hits	15
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SON_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.110241 (rank : 48)
Query Neighborhood Hits	213	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BCL9_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.093506 (rank : 89)
Query Neighborhood Hits	213	Target Neighborhood Hits	770	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CD2_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.064648 (rank : 237)
Query Neighborhood Hits	213	Target Neighborhood Hits	504	Shared Neighborhood Hits	47
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

FOXN4_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.017969 (rank : 399)
Query Neighborhood Hits	213	Target Neighborhood Hits	248	Shared Neighborhood Hits	15
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

K0310_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.090734 (rank : 93)
Query Neighborhood Hits	213	Target Neighborhood Hits	420	Shared Neighborhood Hits	49
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MYO15_HUMAN
θ value	1.38821 (rank : 88)	NC score	0.031364 (rank : 369)
Query Neighborhood Hits	213	Target Neighborhood Hits	671	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TLN1_HUMAN
θ value	1.38821 (rank : 89)	NC score	0.020792 (rank : 394)
Query Neighborhood Hits	213	Target Neighborhood Hits	218	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

ZN142_HUMAN
θ value	1.38821 (rank : 90)	NC score	0.006536 (rank : 431)
Query Neighborhood Hits	213	Target Neighborhood Hits	1007	Shared Neighborhood Hits	46
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

CYH4_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.085623 (rank : 111)
Query Neighborhood Hits	213	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

FA47A_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.129591 (rank : 21)
Query Neighborhood Hits	213	Target Neighborhood Hits	451	Shared Neighborhood Hits	51
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FMN2_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.103382 (rank : 63)
Query Neighborhood Hits	213	Target Neighborhood Hits	349	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

GAK6_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.067075 (rank : 218)
Query Neighborhood Hits	213	Target Neighborhood Hits	392	Shared Neighborhood Hits	34
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MBB1A_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.047198 (rank : 344)
Query Neighborhood Hits	213	Target Neighborhood Hits	665	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MRP2_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.006354 (rank : 432)
Query Neighborhood Hits	213	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

RASA1_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.101243 (rank : 68)
Query Neighborhood Hits	213	Target Neighborhood Hits	258	Shared Neighborhood Hits	30
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RP3A_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.036156 (rank : 357)
Query Neighborhood Hits	213	Target Neighborhood Hits	510	Shared Neighborhood Hits	47
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CNKR2_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.070606 (rank : 202)
Query Neighborhood Hits	213	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.070644 (rank : 201)
Query Neighborhood Hits	213	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

COA2_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.024929 (rank : 382)
Query Neighborhood Hits	213	Target Neighborhood Hits	184	Shared Neighborhood Hits	13
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

CYH4_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.081233 (rank : 125)
Query Neighborhood Hits	213	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

ERBB2_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.006901 (rank : 428)
Query Neighborhood Hits	213	Target Neighborhood Hits	1073	Shared Neighborhood Hits	22
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

GR65_MOUSE
θ value	2.36792 (rank : 104)	NC score	0.021988 (rank : 391)
Query Neighborhood Hits	213	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q91X51, Q9D3L9	Gene names	Gorasp1
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65).

LAEVR_HUMAN
θ value	2.36792 (rank : 105)	NC score	0.011576 (rank : 414)
Query Neighborhood Hits	213	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

RASA2_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.031420 (rank : 368)
Query Neighborhood Hits	213	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SCAP_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.020774 (rank : 395)
Query Neighborhood Hits	213	Target Neighborhood Hits	368	Shared Neighborhood Hits	16
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SMR2C_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.056437 (rank : 288)
Query Neighborhood Hits	213	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	O35985	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform gamma precursor (Salivary protein MSG2, isoform gamma).

SMR2D_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.057467 (rank : 277)
Query Neighborhood Hits	213	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	O35979	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform delta precursor (Salivary protein MSG2, isoform delta).

TULP4_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.044260 (rank : 346)
Query Neighborhood Hits	213	Target Neighborhood Hits	426	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

URP2_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.036126 (rank : 358)
Query Neighborhood Hits	213	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

CBP_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.075074 (rank : 167)
Query Neighborhood Hits	213	Target Neighborhood Hits	941	Shared Neighborhood Hits	88
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FXL19_MOUSE
θ value	3.0926 (rank : 113)	NC score	0.023513 (rank : 387)
Query Neighborhood Hits	213	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GLI2_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.005252 (rank : 436)
Query Neighborhood Hits	213	Target Neighborhood Hits	971	Shared Neighborhood Hits	32
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NOS3_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.011378 (rank : 415)
Query Neighborhood Hits	213	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NSD1_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.040762 (rank : 350)
Query Neighborhood Hits	213	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

P2RX2_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.015775 (rank : 402)
Query Neighborhood Hits	213	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

RUNX3_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.022351 (rank : 390)
Query Neighborhood Hits	213	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SAM14_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.034867 (rank : 360)
Query Neighborhood Hits	213	Target Neighborhood Hits	91	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SC24A_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.076301 (rank : 154)
Query Neighborhood Hits	213	Target Neighborhood Hits	394	Shared Neighborhood Hits	53
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SC24C_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.080667 (rank : 127)
Query Neighborhood Hits	213	Target Neighborhood Hits	662	Shared Neighborhood Hits	55
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TAF6L_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.025403 (rank : 379)
Query Neighborhood Hits	213	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

ZIM10_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.060899 (rank : 261)
Query Neighborhood Hits	213	Target Neighborhood Hits	577	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.051377 (rank : 331)
Query Neighborhood Hits	213	Target Neighborhood Hits	566	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BCLF1_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.023544 (rank : 386)
Query Neighborhood Hits	213	Target Neighborhood Hits	298	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CECR2_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.038044 (rank : 355)
Query Neighborhood Hits	213	Target Neighborhood Hits	543	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

DGKH_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.030716 (rank : 370)
Query Neighborhood Hits	213	Target Neighborhood Hits	255	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DOCK4_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.029799 (rank : 373)
Query Neighborhood Hits	213	Target Neighborhood Hits	237	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.027007 (rank : 378)
Query Neighborhood Hits	213	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

LARP1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.030351 (rank : 371)
Query Neighborhood Hits	213	Target Neighborhood Hits	242	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

MILK1_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.080154 (rank : 131)
Query Neighborhood Hits	213	Target Neighborhood Hits	788	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NADAP_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.022742 (rank : 388)
Query Neighborhood Hits	213	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

RAD9A_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.016117 (rank : 400)
Query Neighborhood Hits	213	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0F6, Q8QZZ3	Gene names	Rad9a, Rad9
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (Rad9-like protein) (mRAD9).

RIPK3_MOUSE
θ value	4.03905 (rank : 134)	NC score	0.004759 (rank : 438)
Query Neighborhood Hits	213	Target Neighborhood Hits	867	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

SAM14_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.033872 (rank : 364)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SP7_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.003537 (rank : 441)
Query Neighborhood Hits	213	Target Neighborhood Hits	756	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

STMN1_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.012561 (rank : 410)
Query Neighborhood Hits	213	Target Neighborhood Hits	560	Shared Neighborhood Hits	13
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

ZN645_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.056838 (rank : 284)
Query Neighborhood Hits	213	Target Neighborhood Hits	265	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ANK3_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.008837 (rank : 421)
Query Neighborhood Hits	213	Target Neighborhood Hits	853	Shared Neighborhood Hits	34
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR11_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.028370 (rank : 376)
Query Neighborhood Hits	213	Target Neighborhood Hits	1289	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BLK_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.013141 (rank : 407)
Query Neighborhood Hits	213	Target Neighborhood Hits	994	Shared Neighborhood Hits	19
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BSN_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.089465 (rank : 98)
Query Neighborhood Hits	213	Target Neighborhood Hits	2057	Shared Neighborhood Hits	118
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BTBDC_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.031859 (rank : 367)
Query Neighborhood Hits	213	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CSPG5_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.029135 (rank : 375)
Query Neighborhood Hits	213	Target Neighborhood Hits	199	Shared Neighborhood Hits	19
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

F120C_HUMAN
θ value	5.27518 (rank : 145)	NC score	0.038721 (rank : 354)
Query Neighborhood Hits	213	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

IF4B_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.021829 (rank : 392)
Query Neighborhood Hits	213	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

INADL_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.007402 (rank : 427)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INVS_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.010010 (rank : 417)
Query Neighborhood Hits	213	Target Neighborhood Hits	609	Shared Neighborhood Hits	32
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MAGI2_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.014932 (rank : 405)
Query Neighborhood Hits	213	Target Neighborhood Hits	370	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MINT_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.054570 (rank : 298)
Query Neighborhood Hits	213	Target Neighborhood Hits	1514	Shared Neighborhood Hits	73
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MTR1L_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.001151 (rank : 444)
Query Neighborhood Hits	213	Target Neighborhood Hits	1180	Shared Neighborhood Hits	24
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NECD_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.022652 (rank : 389)
Query Neighborhood Hits	213	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

PKHA4_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.062110 (rank : 256)
Query Neighborhood Hits	213	Target Neighborhood Hits	283	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RP1L1_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.043704 (rank : 348)
Query Neighborhood Hits	213	Target Neighborhood Hits	1072	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SPR1B_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.054328 (rank : 300)
Query Neighborhood Hits	213	Target Neighborhood Hits	395	Shared Neighborhood Hits	32
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SYNJ1_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.073917 (rank : 180)
Query Neighborhood Hits	213	Target Neighborhood Hits	498	Shared Neighborhood Hits	91
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARSH_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.114418 (rank : 38)
Query Neighborhood Hits	213	Target Neighborhood Hits	768	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TSC1_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.009012 (rank : 419)
Query Neighborhood Hits	213	Target Neighborhood Hits	765	Shared Neighborhood Hits	15
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

Z3H7A_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.015396 (rank : 403)
Query Neighborhood Hits	213	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

AP180_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.059200 (rank : 267)
Query Neighborhood Hits	213	Target Neighborhood Hits	183	Shared Neighborhood Hits	30
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

AP180_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.067009 (rank : 219)
Query Neighborhood Hits	213	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

CD248_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.039754 (rank : 352)
Query Neighborhood Hits	213	Target Neighborhood Hits	578	Shared Neighborhood Hits	37
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CS007_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.074428 (rank : 178)
Query Neighborhood Hits	213	Target Neighborhood Hits	464	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

FOXN1_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.024629 (rank : 383)
Query Neighborhood Hits	213	Target Neighborhood Hits	300	Shared Neighborhood Hits	25
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GGA3_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.015214 (rank : 404)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GP112_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.015817 (rank : 401)
Query Neighborhood Hits	213	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

HCLS1_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.034350 (rank : 362)
Query Neighborhood Hits	213	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

IWS1_MOUSE
θ value	6.88961 (rank : 168)	NC score	0.036966 (rank : 356)
Query Neighborhood Hits	213	Target Neighborhood Hits	1258	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LCP2_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.073811 (rank : 182)
Query Neighborhood Hits	213	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LGMN_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.012287 (rank : 411)
Query Neighborhood Hits	213	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q99538, O00123	Gene names	LGMN, PRSC1
Domain Architecture
Description	Legumain precursor (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1).

LPP_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.047626 (rank : 343)
Query Neighborhood Hits	213	Target Neighborhood Hits	775	Shared Neighborhood Hits	57
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MKL1_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.043468 (rank : 349)
Query Neighborhood Hits	213	Target Neighborhood Hits	667	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NLGN3_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.021394 (rank : 393)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

PO2F2_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.006890 (rank : 429)
Query Neighborhood Hits	213	Target Neighborhood Hits	379	Shared Neighborhood Hits	16
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

RASL1_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.013944 (rank : 406)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RUNX2_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.020097 (rank : 397)
Query Neighborhood Hits	213	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.020184 (rank : 396)
Query Neighborhood Hits	213	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SL9A9_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.008323 (rank : 422)
Query Neighborhood Hits	213	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVB4, Q8NAB9	Gene names	SLC9A9, NHE9
Domain Architecture
Description	Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9).

TBX22_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.004203 (rank : 439)
Query Neighborhood Hits	213	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

WASF3_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.066151 (rank : 225)
Query Neighborhood Hits	213	Target Neighborhood Hits	204	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

ZN438_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.018010 (rank : 398)
Query Neighborhood Hits	213	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZN467_MOUSE
θ value	6.88961 (rank : 182)	NC score	-0.000163 (rank : 446)
Query Neighborhood Hits	213	Target Neighborhood Hits	794	Shared Neighborhood Hits	15
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

AATK_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.024280 (rank : 384)
Query Neighborhood Hits	213	Target Neighborhood Hits	1243	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ATX7_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.039516 (rank : 353)
Query Neighborhood Hits	213	Target Neighborhood Hits	351	Shared Neighborhood Hits	34
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BCAR1_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.061002 (rank : 260)
Query Neighborhood Hits	213	Target Neighborhood Hits	554	Shared Neighborhood Hits	59
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BLNK_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.050881 (rank : 335)
Query Neighborhood Hits	213	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CAC1B_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.007936 (rank : 424)
Query Neighborhood Hits	213	Target Neighborhood Hits	351	Shared Neighborhood Hits	19
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CDKL5_HUMAN
θ value	8.99809 (rank : 188)	NC score	-0.000392 (rank : 447)
Query Neighborhood Hits	213	Target Neighborhood Hits	967	Shared Neighborhood Hits	19
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CTRO_MOUSE
θ value	8.99809 (rank : 189)	NC score	-0.001503 (rank : 448)
Query Neighborhood Hits	213	Target Neighborhood Hits	2344	Shared Neighborhood Hits	37
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EGR1_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.005371 (rank : 434)
Query Neighborhood Hits	213	Target Neighborhood Hits	816	Shared Neighborhood Hits	33
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

EGR4_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.003893 (rank : 440)
Query Neighborhood Hits	213	Target Neighborhood Hits	939	Shared Neighborhood Hits	33
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

GAB1_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.072767 (rank : 187)
Query Neighborhood Hits	213	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GALT1_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.005847 (rank : 433)
Query Neighborhood Hits	213	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q10472, Q86TJ7, Q9UM86	Gene names	GALNT1
Domain Architecture
Description	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) [Contains: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form].

GGA1_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.012659 (rank : 409)
Query Neighborhood Hits	213	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GLIS3_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.007418 (rank : 426)
Query Neighborhood Hits	213	Target Neighborhood Hits	861	Shared Neighborhood Hits	30
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

GLTL1_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.006602 (rank : 430)
Query Neighborhood Hits	213	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ61	Gene names	Galntl1
Domain Architecture	No domain graphic available
Description	Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase- like protein 1) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1).

IF4G1_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.053329 (rank : 305)
Query Neighborhood Hits	213	Target Neighborhood Hits	534	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1543_MOUSE
θ value	8.99809 (rank : 198)	NC score	0.075538 (rank : 161)
Query Neighborhood Hits	213	Target Neighborhood Hits	497	Shared Neighborhood Hits	50
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KCNQ5_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.005285 (rank : 435)
Query Neighborhood Hits	213	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KIF25_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.002713 (rank : 443)
Query Neighborhood Hits	213	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIL4, O94775	Gene names	KIF25, KNSL3
Domain Architecture
Description	Kinesin-like protein KIF25 (Kinesin-like protein 3).

PALB2_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.011756 (rank : 413)
Query Neighborhood Hits	213	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PKHA2_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.033317 (rank : 366)
Query Neighborhood Hits	213	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PRGC2_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.027152 (rank : 377)
Query Neighborhood Hits	213	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RHG25_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.035778 (rank : 359)
Query Neighborhood Hits	213	Target Neighborhood Hits	550	Shared Neighborhood Hits	30
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.044740 (rank : 345)
Query Neighborhood Hits	213	Target Neighborhood Hits	492	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RM19_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.011912 (rank : 412)
Query Neighborhood Hits	213	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P49406, Q53TX9	Gene names	MRPL19, KIAA0104
Domain Architecture
Description	39S ribosomal protein L19, mitochondrial precursor (L19mt) (MRP-L19) (MRP-L15).

SALL2_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.005085 (rank : 437)
Query Neighborhood Hits	213	Target Neighborhood Hits	836	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SL9A2_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.007827 (rank : 425)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBY0	Gene names	SLC9A2, NHE2
Domain Architecture
Description	Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2).

SM1L2_MOUSE
θ value	8.99809 (rank : 209)	NC score	-0.000044 (rank : 445)
Query Neighborhood Hits	213	Target Neighborhood Hits	918	Shared Neighborhood Hits	10
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SNPC4_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.023752 (rank : 385)
Query Neighborhood Hits	213	Target Neighborhood Hits	237	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SP7_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.002838 (rank : 442)
Query Neighborhood Hits	213	Target Neighborhood Hits	734	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

TMG1_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.008293 (rank : 423)
Query Neighborhood Hits	213	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TRIP6_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.012740 (rank : 408)
Query Neighborhood Hits	213	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

3BP1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.068503 (rank : 212)
Query Neighborhood Hits	213	Target Neighborhood Hits	376	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.055107 (rank : 294)
Query Neighborhood Hits	213	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ALEX_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.074924 (rank : 173)
Query Neighborhood Hits	213	Target Neighborhood Hits	361	Shared Neighborhood Hits	65
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.061218 (rank : 258)
Query Neighborhood Hits	213	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

APS_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.079422 (rank : 135)
Query Neighborhood Hits	213	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.066920 (rank : 222)
Query Neighborhood Hits	213	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ARI1A_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.057280 (rank : 278)
Query Neighborhood Hits	213	Target Neighborhood Hits	787	Shared Neighborhood Hits	82
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATN1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.108171 (rank : 52)
Query Neighborhood Hits	213	Target Neighborhood Hits	676	Shared Neighborhood Hits	87
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.054259 (rank : 301)
Query Neighborhood Hits	213	Target Neighborhood Hits	443	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

AUTS2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.051787 (rank : 326)
Query Neighborhood Hits	213	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAG3_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.068531 (rank : 211)
Query Neighborhood Hits	213	Target Neighborhood Hits	314	Shared Neighborhood Hits	52
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.076786 (rank : 149)
Query Neighborhood Hits	213	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.073821 (rank : 181)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.107117 (rank : 54)
Query Neighborhood Hits	213	Target Neighborhood Hits	931	Shared Neighborhood Hits	112
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.084978 (rank : 112)
Query Neighborhood Hits	213	Target Neighborhood Hits	947	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.063665 (rank : 246)
Query Neighborhood Hits	213	Target Neighborhood Hits	490	Shared Neighborhood Hits	53
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.074965 (rank : 171)
Query Neighborhood Hits	213	Target Neighborhood Hits	518	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCAR1_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.051767 (rank : 328)
Query Neighborhood Hits	213	Target Neighborhood Hits	438	Shared Neighborhood Hits	49
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR3_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.075009 (rank : 170)
Query Neighborhood Hits	213	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.077502 (rank : 148)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BRD4_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.075523 (rank : 162)
Query Neighborhood Hits	213	Target Neighborhood Hits	851	Shared Neighborhood Hits	104
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.079861 (rank : 133)
Query Neighborhood Hits	213	Target Neighborhood Hits	845	Shared Neighborhood Hits	111
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BSN_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.075608 (rank : 157)
Query Neighborhood Hits	213	Target Neighborhood Hits	1537	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CBP_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.068083 (rank : 215)
Query Neighborhood Hits	213	Target Neighborhood Hits	1051	Shared Neighborhood Hits	92
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCNK_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.099118 (rank : 72)
Query Neighborhood Hits	213	Target Neighborhood Hits	350	Shared Neighborhood Hits	92
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.078140 (rank : 144)
Query Neighborhood Hits	213	Target Neighborhood Hits	168	Shared Neighborhood Hits	36
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CHIN_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.050659 (rank : 337)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.053475 (rank : 304)
Query Neighborhood Hits	213	Target Neighborhood Hits	229	Shared Neighborhood Hits	14
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.052881 (rank : 312)
Query Neighborhood Hits	213	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CIC_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.075301 (rank : 165)
Query Neighborhood Hits	213	Target Neighborhood Hits	992	Shared Neighborhood Hits	99
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.066982 (rank : 220)
Query Neighborhood Hits	213	Target Neighborhood Hits	742	Shared Neighborhood Hits	86
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CITE4_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.053126 (rank : 307)
Query Neighborhood Hits	213	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CJ078_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.101518 (rank : 66)
Query Neighborhood Hits	213	Target Neighborhood Hits	559	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.080284 (rank : 128)
Query Neighborhood Hits	213	Target Neighborhood Hits	408	Shared Neighborhood Hits	40
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.129094 (rank : 22)
Query Neighborhood Hits	213	Target Neighborhood Hits	267	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.129982 (rank : 20)
Query Neighborhood Hits	213	Target Neighborhood Hits	233	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.111181 (rank : 43)
Query Neighborhood Hits	213	Target Neighborhood Hits	385	Shared Neighborhood Hits	60
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNKR1_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.052931 (rank : 309)
Query Neighborhood Hits	213	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNOT3_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.059236 (rank : 266)
Query Neighborhood Hits	213	Target Neighborhood Hits	425	Shared Neighborhood Hits	50
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO039_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.062426 (rank : 253)
Query Neighborhood Hits	213	Target Neighborhood Hits	264	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO039_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.061871 (rank : 257)
Query Neighborhood Hits	213	Target Neighborhood Hits	445	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CPSF6_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.103937 (rank : 61)
Query Neighborhood Hits	213	Target Neighborhood Hits	359	Shared Neighborhood Hits	71
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.106833 (rank : 55)
Query Neighborhood Hits	213	Target Neighborhood Hits	356	Shared Neighborhood Hits	70
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRKL_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.072686 (rank : 189)
Query Neighborhood Hits	213	Target Neighborhood Hits	313	Shared Neighborhood Hits	13
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.069173 (rank : 207)
Query Neighborhood Hits	213	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.081355 (rank : 123)
Query Neighborhood Hits	213	Target Neighborhood Hits	308	Shared Neighborhood Hits	13
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.080184 (rank : 129)
Query Neighborhood Hits	213	Target Neighborhood Hits	314	Shared Neighborhood Hits	14
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRTC1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.078684 (rank : 137)
Query Neighborhood Hits	213	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS007_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.054413 (rank : 299)
Query Neighborhood Hits	213	Target Neighborhood Hits	401	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS016_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.113852 (rank : 39)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DAPP1_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.075583 (rank : 159)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.072118 (rank : 192)
Query Neighborhood Hits	213	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DGKK_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.066865 (rank : 223)
Query Neighborhood Hits	213	Target Neighborhood Hits	378	Shared Neighborhood Hits	66
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.066766 (rank : 224)
Query Neighborhood Hits	213	Target Neighborhood Hits	784	Shared Neighborhood Hits	91
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.063777 (rank : 245)
Query Neighborhood Hits	213	Target Neighborhood Hits	839	Shared Neighborhood Hits	79
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

EFS_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.065519 (rank : 230)
Query Neighborhood Hits	213	Target Neighborhood Hits	348	Shared Neighborhood Hits	41
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

ENAH_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.097571 (rank : 76)
Query Neighborhood Hits	213	Target Neighborhood Hits	919	Shared Neighborhood Hits	103
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.070841 (rank : 199)
Query Neighborhood Hits	213	Target Neighborhood Hits	821	Shared Neighborhood Hits	104
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FMN1A_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.073085 (rank : 186)
Query Neighborhood Hits	213	Target Neighborhood Hits	423	Shared Neighborhood Hits	80
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.078377 (rank : 141)
Query Neighborhood Hits	213	Target Neighborhood Hits	447	Shared Neighborhood Hits	85
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.098722 (rank : 73)
Query Neighborhood Hits	213	Target Neighborhood Hits	484	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.083904 (rank : 114)
Query Neighborhood Hits	213	Target Neighborhood Hits	529	Shared Neighborhood Hits	91
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.060144 (rank : 263)
Query Neighborhood Hits	213	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GAK10_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.059236 (rank : 265)
Query Neighborhood Hits	213	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK3_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.054960 (rank : 295)
Query Neighborhood Hits	213	Target Neighborhood Hits	182	Shared Neighborhood Hits	19
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK7_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.058280 (rank : 272)
Query Neighborhood Hits	213	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

GAK8_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.056862 (rank : 282)
Query Neighborhood Hits	213	Target Neighborhood Hits	145	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GBF1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.054722 (rank : 296)
Query Neighborhood Hits	213	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GGN_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.110243 (rank : 47)
Query Neighborhood Hits	213	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.102247 (rank : 65)
Query Neighborhood Hits	213	Target Neighborhood Hits	311	Shared Neighborhood Hits	76
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRAP2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.073234 (rank : 185)
Query Neighborhood Hits	213	Target Neighborhood Hits	304	Shared Neighborhood Hits	13
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.066952 (rank : 221)
Query Neighborhood Hits	213	Target Neighborhood Hits	297	Shared Neighborhood Hits	13
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.078296 (rank : 142)
Query Neighborhood Hits	213	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.075126 (rank : 166)
Query Neighborhood Hits	213	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.062696 (rank : 251)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.062676 (rank : 252)
Query Neighborhood Hits	213	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GSCR1_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.125435 (rank : 25)
Query Neighborhood Hits	213	Target Neighborhood Hits	674	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HSH2D_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.063285 (rank : 248)
Query Neighborhood Hits	213	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.075015 (rank : 169)
Query Neighborhood Hits	213	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IF35_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.051678 (rank : 329)
Query Neighborhood Hits	213	Target Neighborhood Hits	210	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IQEC2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.064967 (rank : 234)
Query Neighborhood Hits	213	Target Neighborhood Hits	403	Shared Neighborhood Hits	85
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.074738 (rank : 176)
Query Neighborhood Hits	213	Target Neighborhood Hits	417	Shared Neighborhood Hits	88
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.050043 (rank : 339)
Query Neighborhood Hits	213	Target Neighborhood Hits	274	Shared Neighborhood Hits	36
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

K1543_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.055276 (rank : 292)
Query Neighborhood Hits	213	Target Neighborhood Hits	435	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.060470 (rank : 262)
Query Neighborhood Hits	213	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1802_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.075793 (rank : 155)
Query Neighborhood Hits	213	Target Neighborhood Hits	1378	Shared Neighborhood Hits	93
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LNK_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.075327 (rank : 164)
Query Neighborhood Hits	213	Target Neighborhood Hits	151	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.087996 (rank : 104)
Query Neighborhood Hits	213	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MADCA_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.062292 (rank : 254)
Query Neighborhood Hits	213	Target Neighborhood Hits	221	Shared Neighborhood Hits	48
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP4_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.078559 (rank : 139)
Query Neighborhood Hits	213	Target Neighborhood Hits	428	Shared Neighborhood Hits	43
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.052573 (rank : 317)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	35
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.071422 (rank : 196)
Query Neighborhood Hits	213	Target Neighborhood Hits	204	Shared Neighborhood Hits	25
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.052696 (rank : 315)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MBD6_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.120423 (rank : 31)
Query Neighborhood Hits	213	Target Neighborhood Hits	349	Shared Neighborhood Hits	75
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.072729 (rank : 188)
Query Neighborhood Hits	213	Target Neighborhood Hits	1446	Shared Neighborhood Hits	80
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.075040 (rank : 168)
Query Neighborhood Hits	213	Target Neighborhood Hits	998	Shared Neighborhood Hits	69
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MINT_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.053077 (rank : 308)
Query Neighborhood Hits	213	Target Neighborhood Hits	1291	Shared Neighborhood Hits	74
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.087203 (rank : 107)
Query Neighborhood Hits	213	Target Neighborhood Hits	1788	Shared Neighborhood Hits	127
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.088366 (rank : 102)
Query Neighborhood Hits	213	Target Neighborhood Hits	722	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MNT_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.070581 (rank : 203)
Query Neighborhood Hits	213	Target Neighborhood Hits	496	Shared Neighborhood Hits	67
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.065556 (rank : 229)
Query Neighborhood Hits	213	Target Neighborhood Hits	432	Shared Neighborhood Hits	60
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MUC1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.081487 (rank : 122)
Query Neighborhood Hits	213	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.074760 (rank : 175)
Query Neighborhood Hits	213	Target Neighborhood Hits	906	Shared Neighborhood Hits	81
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.120098 (rank : 32)
Query Neighborhood Hits	213	Target Neighborhood Hits	538	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCK1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.073347 (rank : 184)
Query Neighborhood Hits	213	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.070066 (rank : 205)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOA6_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.068992 (rank : 209)
Query Neighborhood Hits	213	Target Neighborhood Hits	1202	Shared Neighborhood Hits	102
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.062744 (rank : 250)
Query Neighborhood Hits	213	Target Neighborhood Hits	1076	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOR2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.069398 (rank : 206)
Query Neighborhood Hits	213	Target Neighborhood Hits	870	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NELFA_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.052290 (rank : 322)
Query Neighborhood Hits	213	Target Neighborhood Hits	161	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.063388 (rank : 247)
Query Neighborhood Hits	213	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NOLC1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.057059 (rank : 280)
Query Neighborhood Hits	213	Target Neighborhood Hits	452	Shared Neighborhood Hits	34
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NU214_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.064905 (rank : 235)
Query Neighborhood Hits	213	Target Neighborhood Hits	657	Shared Neighborhood Hits	53
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.054244 (rank : 302)
Query Neighborhood Hits	213	Target Neighborhood Hits	584	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCLO_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.099951 (rank : 70)
Query Neighborhood Hits	213	Target Neighborhood Hits	2046	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCQAP_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.058960 (rank : 268)
Query Neighborhood Hits	213	Target Neighborhood Hits	549	Shared Neighborhood Hits	61
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PDC6I_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.052885 (rank : 311)
Query Neighborhood Hits	213	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.050126 (rank : 338)
Query Neighborhood Hits	213	Target Neighborhood Hits	275	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDCD7_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.057159 (rank : 279)
Query Neighborhood Hits	213	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PELP1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.078794 (rank : 136)
Query Neighborhood Hits	213	Target Neighborhood Hits	596	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.077709 (rank : 145)
Query Neighborhood Hits	213	Target Neighborhood Hits	709	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PI5PA_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.056844 (rank : 283)
Query Neighborhood Hits	213	Target Neighborhood Hits	749	Shared Neighborhood Hits	71
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PI5PA_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.052545 (rank : 319)
Query Neighborhood Hits	213	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PLCG1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.065859 (rank : 226)
Query Neighborhood Hits	213	Target Neighborhood Hits	293	Shared Neighborhood Hits	17
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.065835 (rank : 227)
Query Neighborhood Hits	213	Target Neighborhood Hits	314	Shared Neighborhood Hits	17
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.064605 (rank : 238)
Query Neighborhood Hits	213	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PO121_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.070672 (rank : 200)
Query Neighborhood Hits	213	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.058274 (rank : 273)
Query Neighborhood Hits	213	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRB3_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.147294 (rank : 16)
Query Neighborhood Hits	213	Target Neighborhood Hits	318	Shared Neighborhood Hits	79
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.147745 (rank : 15)
Query Neighborhood Hits	213	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRCC_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.062948 (rank : 249)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.108942 (rank : 50)
Query Neighborhood Hits	213	Target Neighborhood Hits	764	Shared Neighborhood Hits	93
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.089436 (rank : 99)
Query Neighborhood Hits	213	Target Neighborhood Hits	624	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.152574 (rank : 13)
Query Neighborhood Hits	213	Target Neighborhood Hits	385	Shared Neighborhood Hits	84
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.167574 (rank : 10)
Query Neighborhood Hits	213	Target Neighborhood Hits	347	Shared Neighborhood Hits	87
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.079582 (rank : 134)
Query Neighborhood Hits	213	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.098134 (rank : 75)
Query Neighborhood Hits	213	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.058680 (rank : 269)
Query Neighborhood Hits	213	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.155068 (rank : 12)
Query Neighborhood Hits	213	Target Neighborhood Hits	460	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.122824 (rank : 28)
Query Neighborhood Hits	213	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.080744 (rank : 126)
Query Neighborhood Hits	213	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRRT1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.051778 (rank : 327)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT1_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.055451 (rank : 291)
Query Neighborhood Hits	213	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PS1C2_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.082036 (rank : 119)
Query Neighborhood Hits	213	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.077687 (rank : 146)
Query Neighborhood Hits	213	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN11_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.052034 (rank : 325)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.052041 (rank : 324)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

RBM12_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.051091 (rank : 332)
Query Neighborhood Hits	213	Target Neighborhood Hits	298	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.061197 (rank : 259)
Query Neighborhood Hits	213	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RERE_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.097265 (rank : 77)
Query Neighborhood Hits	213	Target Neighborhood Hits	779	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.094209 (rank : 87)
Query Neighborhood Hits	213	Target Neighborhood Hits	785	Shared Neighborhood Hits	107
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RIN2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.076518 (rank : 152)
Query Neighborhood Hits	213	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.087856 (rank : 105)
Query Neighborhood Hits	213	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN3_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.083534 (rank : 116)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.084881 (rank : 113)
Query Neighborhood Hits	213	Target Neighborhood Hits	239	Shared Neighborhood Hits	75
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RNC_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.055219 (rank : 293)
Query Neighborhood Hits	213	Target Neighborhood Hits	176	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

RPB1_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.053245 (rank : 306)
Query Neighborhood Hits	213	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.053742 (rank : 303)
Query Neighborhood Hits	213	Target Neighborhood Hits	363	Shared Neighborhood Hits	55
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RU1C_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.064331 (rank : 242)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.064728 (rank : 236)
Query Neighborhood Hits	213	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SC24D_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.054656 (rank : 297)
Query Neighborhood Hits	213	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SELPL_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.064391 (rank : 241)
Query Neighborhood Hits	213	Target Neighborhood Hits	588	Shared Neighborhood Hits	50
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.076534 (rank : 150)
Query Neighborhood Hits	213	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.081506 (rank : 121)
Query Neighborhood Hits	213	Target Neighborhood Hits	690	Shared Neighborhood Hits	98
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.088602 (rank : 101)
Query Neighborhood Hits	213	Target Neighborhood Hits	287	Shared Neighborhood Hits	78
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.078497 (rank : 140)
Query Neighborhood Hits	213	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.133102 (rank : 17)
Query Neighborhood Hits	213	Target Neighborhood Hits	263	Shared Neighborhood Hits	79
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.132036 (rank : 18)
Query Neighborhood Hits	213	Target Neighborhood Hits	247	Shared Neighborhood Hits	76
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.090853 (rank : 92)
Query Neighborhood Hits	213	Target Neighborhood Hits	986	Shared Neighborhood Hits	106
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.095187 (rank : 82)
Query Neighborhood Hits	213	Target Neighborhood Hits	958	Shared Neighborhood Hits	101
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.087066 (rank : 108)
Query Neighborhood Hits	213	Target Neighborhood Hits	368	Shared Neighborhood Hits	68
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.067358 (rank : 216)
Query Neighborhood Hits	213	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.064564 (rank : 239)
Query Neighborhood Hits	213	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SH21A_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.100214 (rank : 69)
Query Neighborhood Hits	213	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.094285 (rank : 86)
Query Neighborhood Hits	213	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.104871 (rank : 59)
Query Neighborhood Hits	213	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.077576 (rank : 147)
Query Neighborhood Hits	213	Target Neighborhood Hits	101	Shared Neighborhood Hits	11
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.104593 (rank : 60)
Query Neighborhood Hits	213	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.109580 (rank : 49)
Query Neighborhood Hits	213	Target Neighborhood Hits	179	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH2D3_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.052471 (rank : 321)
Query Neighborhood Hits	213	Target Neighborhood Hits	188	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.056272 (rank : 289)
Query Neighborhood Hits	213	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHC1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.072115 (rank : 193)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.068200 (rank : 214)
Query Neighborhood Hits	213	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.090388 (rank : 94)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.090263 (rank : 96)
Query Neighborhood Hits	213	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.076344 (rank : 153)
Query Neighborhood Hits	213	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.080157 (rank : 130)
Query Neighborhood Hits	213	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.050835 (rank : 336)
Query Neighborhood Hits	213	Target Neighborhood Hits	137	Shared Neighborhood Hits	9
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.052912 (rank : 310)
Query Neighborhood Hits	213	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SLAP2_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.062172 (rank : 255)
Query Neighborhood Hits	213	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.052205 (rank : 323)
Query Neighborhood Hits	213	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SMR1_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.110736 (rank : 45)
Query Neighborhood Hits	213	Target Neighborhood Hits	103	Shared Neighborhood Hits	52
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.116974 (rank : 36)
Query Neighborhood Hits	213	Target Neighborhood Hits	93	Shared Neighborhood Hits	42
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SMR3B_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.072114 (rank : 194)
Query Neighborhood Hits	213	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SMRC2_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.051006 (rank : 333)
Query Neighborhood Hits	213	Target Neighborhood Hits	499	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.055725 (rank : 290)
Query Neighborhood Hits	213	Target Neighborhood Hits	487	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SPRR3_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.052804 (rank : 314)
Query Neighborhood Hits	213	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SRRM1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.119909 (rank : 33)
Query Neighborhood Hits	213	Target Neighborhood Hits	690	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.108460 (rank : 51)
Query Neighborhood Hits	213	Target Neighborhood Hits	966	Shared Neighborhood Hits	94
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.071180 (rank : 198)
Query Neighborhood Hits	213	Target Neighborhood Hits	1296	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.071210 (rank : 197)
Query Neighborhood Hits	213	Target Neighborhood Hits	1470	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYN1_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.085856 (rank : 110)
Query Neighborhood Hits	213	Target Neighborhood Hits	419	Shared Neighborhood Hits	83
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.076527 (rank : 151)
Query Neighborhood Hits	213	Target Neighborhood Hits	363	Shared Neighborhood Hits	81
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.072189 (rank : 190)
Query Neighborhood Hits	213	Target Neighborhood Hits	516	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T22D2_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.079907 (rank : 132)
Query Neighborhood Hits	213	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAF4_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.122101 (rank : 30)
Query Neighborhood Hits	213	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAU_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.065146 (rank : 233)
Query Neighborhood Hits	213	Target Neighborhood Hits	502	Shared Neighborhood Hits	47
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCGAP_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.052538 (rank : 320)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCOF_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.056493 (rank : 287)
Query Neighborhood Hits	213	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.068256 (rank : 213)
Query Neighborhood Hits	213	Target Neighborhood Hits	471	Shared Neighborhood Hits	38
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TENS4_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.052552 (rank : 318)
Query Neighborhood Hits	213	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TM108_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.068775 (rank : 210)
Query Neighborhood Hits	213	Target Neighborhood Hits	336	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.056747 (rank : 286)
Query Neighborhood Hits	213	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TROAP_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.057741 (rank : 275)
Query Neighborhood Hits	213	Target Neighborhood Hits	258	Shared Neighborhood Hits	37
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

VASP_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.056772 (rank : 285)
Query Neighborhood Hits	213	Target Neighborhood Hits	201	Shared Neighborhood Hits	53
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASF1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.075717 (rank : 156)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	82
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.078219 (rank : 143)
Query Neighborhood Hits	213	Target Neighborhood Hits	261	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.106060 (rank : 57)
Query Neighborhood Hits	213	Target Neighborhood Hits	280	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.106287 (rank : 56)
Query Neighborhood Hits	213	Target Neighborhood Hits	315	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.057541 (rank : 276)
Query Neighborhood Hits	213	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WASF4_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.105386 (rank : 58)
Query Neighborhood Hits	213	Target Neighborhood Hits	282	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.152454 (rank : 14)
Query Neighborhood Hits	213	Target Neighborhood Hits	458	Shared Neighborhood Hits	101
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.159536 (rank : 11)
Query Neighborhood Hits	213	Target Neighborhood Hits	392	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.110896 (rank : 44)
Query Neighborhood Hits	213	Target Neighborhood Hits	312	Shared Neighborhood Hits	90
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.119180 (rank : 34)
Query Neighborhood Hits	213	Target Neighborhood Hits	339	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.089578 (rank : 97)
Query Neighborhood Hits	213	Target Neighborhood Hits	195	Shared Neighborhood Hits	71
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.083561 (rank : 115)
Query Neighborhood Hits	213	Target Neighborhood Hits	223	Shared Neighborhood Hits	65
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.122290 (rank : 29)
Query Neighborhood Hits	213	Target Neighborhood Hits	354	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.118552 (rank : 35)
Query Neighborhood Hits	213	Target Neighborhood Hits	362	Shared Neighborhood Hits	79
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.067200 (rank : 217)
Query Neighborhood Hits	213	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.131899 (rank : 19)
Query Neighborhood Hits	213	Target Neighborhood Hits	329	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.124513 (rank : 26)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	90
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.081803 (rank : 120)
Query Neighborhood Hits	213	Target Neighborhood Hits	670	Shared Neighborhood Hits	91
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.113309 (rank : 40)
Query Neighborhood Hits	213	Target Neighborhood Hits	505	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN207_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.101409 (rank : 67)
Query Neighborhood Hits	213	Target Neighborhood Hits	326	Shared Neighborhood Hits	51
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

AB1IP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	213	Target Neighborhood Hits	213	Shared Neighborhood Hits	213
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
NC score	0.951245 (rank : 2)	θ value	4.11024e-170 (rank : 2)
Query Neighborhood Hits	213	Target Neighborhood Hits	181	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

RAPH1_HUMAN
NC score	0.822430 (rank : 3)	θ value	7.37397e-111 (rank : 3)
Query Neighborhood Hits	213	Target Neighborhood Hits	593	Shared Neighborhood Hits	125
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GRB10_MOUSE
NC score	0.725188 (rank : 4)	θ value	2.19075e-38 (rank : 7)
Query Neighborhood Hits	213	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB10_HUMAN
NC score	0.722649 (rank : 5)	θ value	5.76516e-39 (rank : 5)
Query Neighborhood Hits	213	Target Neighborhood Hits	147	Shared Neighborhood Hits	13
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB7_HUMAN
NC score	0.700228 (rank : 6)	θ value	1.24399e-33 (rank : 8)
Query Neighborhood Hits	213	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB14_HUMAN
NC score	0.693165 (rank : 7)	θ value	8.59492e-43 (rank : 4)
Query Neighborhood Hits	213	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_MOUSE
NC score	0.681209 (rank : 8)	θ value	1.6813e-30 (rank : 9)
Query Neighborhood Hits	213	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRB14_MOUSE
NC score	0.676853 (rank : 9)	θ value	9.83387e-39 (rank : 6)
Query Neighborhood Hits	213	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

PRP2_MOUSE
NC score	0.167574 (rank : 10)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	213	Target Neighborhood Hits	347	Shared Neighborhood Hits	87
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

WASIP_MOUSE
NC score	0.159536 (rank : 11)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	213	Target Neighborhood Hits	392	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PRR12_HUMAN
NC score	0.155068 (rank : 12)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	213	Target Neighborhood Hits	460	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRP1_HUMAN
NC score	0.152574 (rank : 13)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	213	Target Neighborhood Hits	385	Shared Neighborhood Hits	84
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WASIP_HUMAN
NC score	0.152454 (rank : 14)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	213	Target Neighborhood Hits	458	Shared Neighborhood Hits	101
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRB4S_HUMAN
NC score	0.147745 (rank : 15)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	213	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRB3_HUMAN
NC score	0.147294 (rank : 16)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	213	Target Neighborhood Hits	318	Shared Neighborhood Hits	79
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SF3A2_HUMAN
NC score	0.133102 (rank : 17)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	213	Target Neighborhood Hits	263	Shared Neighborhood Hits	79
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
NC score	0.132036 (rank : 18)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	213	Target Neighborhood Hits	247	Shared Neighborhood Hits	76
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WIRE_HUMAN
NC score	0.131899 (rank : 19)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	213	Target Neighborhood Hits	329	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CN032_MOUSE
NC score	0.129982 (rank : 20)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	213	Target Neighborhood Hits	233	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

FA47A_HUMAN
NC score	0.129591 (rank : 21)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	213	Target Neighborhood Hits	451	Shared Neighborhood Hits	51
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CN032_HUMAN
NC score	0.129094 (rank : 22)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	213	Target Neighborhood Hits	267	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

NACAM_MOUSE
NC score	0.128565 (rank : 23)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	213	Target Neighborhood Hits	1866	Shared Neighborhood Hits	109
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LCP2_HUMAN
NC score	0.128048 (rank : 24)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	213	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

GSCR1_HUMAN
NC score	0.125435 (rank : 25)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	213	Target Neighborhood Hits	674	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

WIRE_MOUSE
NC score	0.124513 (rank : 26)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	90
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

RGS3_MOUSE
NC score	0.123541 (rank : 27)	θ value	5.44631e-05 (rank : 12)
Query Neighborhood Hits	213	Target Neighborhood Hits	1621	Shared Neighborhood Hits	103
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PRR13_HUMAN
NC score	0.122824 (rank : 28)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	213	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

WBP11_HUMAN
NC score	0.122290 (rank : 29)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	213	Target Neighborhood Hits	354	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

TAF4_HUMAN
NC score	0.122101 (rank : 30)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	213	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MBD6_HUMAN
NC score	0.120423 (rank : 31)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	213	Target Neighborhood Hits	349	Shared Neighborhood Hits	75
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MUC7_HUMAN
NC score	0.120098 (rank : 32)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	213	Target Neighborhood Hits	538	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SRRM1_HUMAN
NC score	0.119909 (rank : 33)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	213	Target Neighborhood Hits	690	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WASL_MOUSE
NC score	0.119180 (rank : 34)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	213	Target Neighborhood Hits	339	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_MOUSE
NC score	0.118552 (rank : 35)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	213	Target Neighborhood Hits	362	Shared Neighborhood Hits	79
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

SMR3A_HUMAN
NC score	0.116974 (rank : 36)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	213	Target Neighborhood Hits	93	Shared Neighborhood Hits	42
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

FA47B_HUMAN
NC score	0.116440 (rank : 37)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	213	Target Neighborhood Hits	431	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TARSH_HUMAN
NC score	0.114418 (rank : 38)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	213	Target Neighborhood Hits	768	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CS016_HUMAN
NC score	0.113852 (rank : 39)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

YLPM1_MOUSE
NC score	0.113309 (rank : 40)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	213	Target Neighborhood Hits	505	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SON_HUMAN
NC score	0.112869 (rank : 41)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	213	Target Neighborhood Hits	1568	Shared Neighborhood Hits	103
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CEL_HUMAN
NC score	0.111278 (rank : 42)	θ value	2.36244e-08 (rank : 10)
Query Neighborhood Hits	213	Target Neighborhood Hits	896	Shared Neighborhood Hits	72
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CN155_HUMAN
NC score	0.111181 (rank : 43)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	213	Target Neighborhood Hits	385	Shared Neighborhood Hits	60
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

WASL_HUMAN
NC score	0.110896 (rank : 44)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	213	Target Neighborhood Hits	312	Shared Neighborhood Hits	90
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

SMR1_MOUSE
NC score	0.110736 (rank : 45)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	213	Target Neighborhood Hits	103	Shared Neighborhood Hits	52
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

MISS_MOUSE
NC score	0.110686 (rank : 46)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	213	Target Neighborhood Hits	444	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

GGN_HUMAN
NC score	0.110243 (rank : 47)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	213	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SON_MOUSE
NC score	0.110241 (rank : 48)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	213	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SH22A_MOUSE
NC score	0.109580 (rank : 49)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	213	Target Neighborhood Hits	179	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

PRG4_HUMAN
NC score	0.108942 (rank : 50)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	213	Target Neighborhood Hits	764	Shared Neighborhood Hits	93
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM1_MOUSE
NC score	0.108460 (rank : 51)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	213	Target Neighborhood Hits	966	Shared Neighborhood Hits	94
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ATN1_HUMAN
NC score	0.108171 (rank : 52)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	213	Target Neighborhood Hits	676	Shared Neighborhood Hits	87
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PRRT3_HUMAN
NC score	0.107670 (rank : 53)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	213	Target Neighborhood Hits	998	Shared Neighborhood Hits	81
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BAT2_HUMAN
NC score	0.107117 (rank : 54)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	213	Target Neighborhood Hits	931	Shared Neighborhood Hits	112
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CPSF6_MOUSE
NC score	0.106833 (rank : 55)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	213	Target Neighborhood Hits	356	Shared Neighborhood Hits	70
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

WASF2_MOUSE
NC score	0.106287 (rank : 56)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	213	Target Neighborhood Hits	315	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF2_HUMAN
NC score	0.106060 (rank : 57)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	213	Target Neighborhood Hits	280	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF4_HUMAN
NC score	0.105386 (rank : 58)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	213	Target Neighborhood Hits	282	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

SH21B_HUMAN
NC score	0.104871 (rank : 59)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	213	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
NC score	0.104593 (rank : 60)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	213	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

CPSF6_HUMAN
NC score	0.103937 (rank : 61)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	213	Target Neighborhood Hits	359	Shared Neighborhood Hits	71
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

BCL9_HUMAN
NC score	0.103864 (rank : 62)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	213	Target Neighborhood Hits	1008	Shared Neighborhood Hits	80
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

FMN2_MOUSE
NC score	0.103382 (rank : 63)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	213	Target Neighborhood Hits	349	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MUC1_HUMAN
NC score	0.102679 (rank : 64)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	213	Target Neighborhood Hits	975	Shared Neighborhood Hits	70
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

GGN_MOUSE
NC score	0.102247 (rank : 65)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	213	Target Neighborhood Hits	311	Shared Neighborhood Hits	76
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CJ078_MOUSE
NC score	0.101518 (rank : 66)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	213	Target Neighborhood Hits	559	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ZN207_HUMAN
NC score	0.101409 (rank : 67)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	213	Target Neighborhood Hits	326	Shared Neighborhood Hits	51
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

RASA1_HUMAN
NC score	0.101243 (rank : 68)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	213	Target Neighborhood Hits	258	Shared Neighborhood Hits	30
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SH21A_HUMAN
NC score	0.100214 (rank : 69)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	213	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

PCLO_HUMAN
NC score	0.099951 (rank : 70)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	213	Target Neighborhood Hits	2046	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RGS3_HUMAN
NC score	0.099176 (rank : 71)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	213	Target Neighborhood Hits	1375	Shared Neighborhood Hits	84
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CCNK_MOUSE
NC score	0.099118 (rank : 72)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	213	Target Neighborhood Hits	350	Shared Neighborhood Hits	92
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

FMN2_HUMAN
NC score	0.098722 (rank : 73)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	213	Target Neighborhood Hits	484	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

CEND1_HUMAN
NC score	0.098530 (rank : 74)	θ value	0.00509761 (rank : 17)
Query Neighborhood Hits	213	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

PRPC_HUMAN
NC score	0.098134 (rank : 75)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	213	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

ENAH_MOUSE
NC score	0.097571 (rank : 76)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	213	Target Neighborhood Hits	919	Shared Neighborhood Hits	103
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

RERE_HUMAN
NC score	0.097265 (rank : 77)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	213	Target Neighborhood Hits	779	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

BAG3_MOUSE
NC score	0.096324 (rank : 78)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	213	Target Neighborhood Hits	513	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CYH1_MOUSE
NC score	0.095938 (rank : 79)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	213	Target Neighborhood Hits	176	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
NC score	0.095630 (rank : 80)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	213	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
NC score	0.095613 (rank : 81)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	213	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

SFPQ_MOUSE
NC score	0.095187 (rank : 82)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	213	Target Neighborhood Hits	958	Shared Neighborhood Hits	101
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

MAGE1_HUMAN
NC score	0.095168 (rank : 83)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	213	Target Neighborhood Hits	1389	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

OGFR_HUMAN
NC score	0.095061 (rank : 84)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	213	Target Neighborhood Hits	1582	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TXND2_HUMAN
NC score	0.094570 (rank : 85)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	213	Target Neighborhood Hits	793	Shared Neighborhood Hits	45
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SH21A_MOUSE
NC score	0.094285 (rank : 86)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	213	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

RERE_MOUSE
NC score	0.094209 (rank : 87)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	213	Target Neighborhood Hits	785	Shared Neighborhood Hits	107
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CYH2_HUMAN
NC score	0.093821 (rank : 88)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	213	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

BCL9_MOUSE
NC score	0.093506 (rank : 89)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	213	Target Neighborhood Hits	770	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CYH2_MOUSE
NC score	0.092849 (rank : 90)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	213	Target Neighborhood Hits	171	Shared Neighborhood Hits	27
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_MOUSE
NC score	0.091069 (rank : 91)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SFPQ_HUMAN
NC score	0.090853 (rank : 92)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	213	Target Neighborhood Hits	986	Shared Neighborhood Hits	106
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

K0310_HUMAN
NC score	0.090734 (rank : 93)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	213	Target Neighborhood Hits	420	Shared Neighborhood Hits	49
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

SHC2_HUMAN
NC score	0.090388 (rank : 94)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

BLNK_MOUSE
NC score	0.090302 (rank : 95)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	213	Target Neighborhood Hits	296	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

SHC2_MOUSE
NC score	0.090263 (rank : 96)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	213	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

WASP_HUMAN
NC score	0.089578 (rank : 97)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	213	Target Neighborhood Hits	195	Shared Neighborhood Hits	71
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

BSN_MOUSE
NC score	0.089465 (rank : 98)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	213	Target Neighborhood Hits	2057	Shared Neighborhood Hits	118
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PRG4_MOUSE
NC score	0.089436 (rank : 99)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	213	Target Neighborhood Hits	624	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCLO_MOUSE
NC score	0.089240 (rank : 100)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	213	Target Neighborhood Hits	2275	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SF01_HUMAN
NC score	0.088602 (rank : 101)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	213	Target Neighborhood Hits	287	Shared Neighborhood Hits	78
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

MLL4_HUMAN
NC score	0.088366 (rank : 102)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	213	Target Neighborhood Hits	722	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

3BP2_HUMAN
NC score	0.088021 (rank : 103)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	213	Target Neighborhood Hits	296	Shared Neighborhood Hits	51
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

LNK_MOUSE
NC score	0.087996 (rank : 104)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	213	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

RIN2_MOUSE
NC score	0.087856 (rank : 105)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	213	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

MLL3_HUMAN
NC score	0.087311 (rank : 106)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	213	Target Neighborhood Hits	1644	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL2_HUMAN
NC score	0.087203 (rank : 107)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	213	Target Neighborhood Hits	1788	Shared Neighborhood Hits	127
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SFR15_HUMAN
NC score	0.087066 (rank : 108)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	213	Target Neighborhood Hits	368	Shared Neighborhood Hits	68
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

GA2L2_MOUSE
NC score	0.086140 (rank : 109)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	213	Target Neighborhood Hits	395	Shared Neighborhood Hits	43
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SYN1_HUMAN
NC score	0.085856 (rank : 110)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	213	Target Neighborhood Hits	419	Shared Neighborhood Hits	83
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CYH4_MOUSE
NC score	0.085623 (rank : 111)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	213	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

BAT2_MOUSE
NC score	0.084978 (rank : 112)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	213	Target Neighborhood Hits	947	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RIN3_MOUSE
NC score	0.084881 (rank : 113)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	213	Target Neighborhood Hits	239	Shared Neighborhood Hits	75
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

FMNL_HUMAN
NC score	0.083904 (rank : 114)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	213	Target Neighborhood Hits	529	Shared Neighborhood Hits	91
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

WASP_MOUSE
NC score	0.083561 (rank : 115)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	213	Target Neighborhood Hits	223	Shared Neighborhood Hits	65
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

RIN3_HUMAN
NC score	0.083534 (rank : 116)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

GAB1_MOUSE
NC score	0.082727 (rank : 117)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	213	Target Neighborhood Hits	233	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

K1802_MOUSE
NC score	0.082463 (rank : 118)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	213	Target Neighborhood Hits	1596	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PS1C2_HUMAN
NC score	0.082036 (rank : 119)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	213	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

YLPM1_HUMAN
NC score	0.081803 (rank : 120)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	213	Target Neighborhood Hits	670	Shared Neighborhood Hits	91
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SET1A_HUMAN
NC score	0.081506 (rank : 121)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	213	Target Neighborhood Hits	690	Shared Neighborhood Hits	98
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MUC1_MOUSE
NC score	0.081487 (rank : 122)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	213	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CRK_HUMAN
NC score	0.081355 (rank : 123)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	213	Target Neighborhood Hits	308	Shared Neighborhood Hits	13
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

TCGAP_HUMAN
NC score	0.081252 (rank : 124)	θ value	0.00134147 (rank : 14)
Query Neighborhood Hits	213	Target Neighborhood Hits	872	Shared Neighborhood Hits	71
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CYH4_HUMAN
NC score	0.081233 (rank : 125)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	213	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

PRR13_MOUSE
NC score	0.080744 (rank : 126)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	213	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SC24C_HUMAN
NC score	0.080667 (rank : 127)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	213	Target Neighborhood Hits	662	Shared Neighborhood Hits	55
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CK024_HUMAN
NC score	0.080284 (rank : 128)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	213	Target Neighborhood Hits	408	Shared Neighborhood Hits	40
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CRK_MOUSE
NC score	0.080184 (rank : 129)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	213	Target Neighborhood Hits	314	Shared Neighborhood Hits	14
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

SHC3_MOUSE
NC score	0.080157 (rank : 130)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	213	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

MILK1_MOUSE
NC score	0.080154 (rank : 131)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	213	Target Neighborhood Hits	788	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

T22D2_HUMAN
NC score	0.079907 (rank : 132)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	213	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

BRD4_MOUSE
NC score	0.079861 (rank : 133)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	213	Target Neighborhood Hits	845	Shared Neighborhood Hits	111
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PRP5_HUMAN
NC score	0.079582 (rank : 134)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	213	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

APS_HUMAN
NC score	0.079422 (rank : 135)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	213	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

PELP1_HUMAN
NC score	0.078794 (rank : 136)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	213	Target Neighborhood Hits	596	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CRTC1_HUMAN
NC score	0.078684 (rank : 137)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	213	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

MTSS1_HUMAN
NC score	0.078643 (rank : 138)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	213	Target Neighborhood Hits	504	Shared Neighborhood Hits	37
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MAP4_HUMAN
NC score	0.078559 (rank : 139)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	213	Target Neighborhood Hits	428	Shared Neighborhood Hits	43
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SF01_MOUSE
NC score	0.078497 (rank : 140)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	213	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

FMN1B_MOUSE
NC score	0.078377 (rank : 141)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	213	Target Neighborhood Hits	447	Shared Neighborhood Hits	85
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

GRAP_HUMAN
NC score	0.078296 (rank : 142)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	213	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

WASF1_MOUSE
NC score	0.078219 (rank : 143)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	213	Target Neighborhood Hits	261	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

CDN1C_HUMAN
NC score	0.078140 (rank : 144)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	213	Target Neighborhood Hits	168	Shared Neighborhood Hits	36
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PELP1_MOUSE
NC score	0.077709 (rank : 145)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	213	Target Neighborhood Hits	709	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PS1C2_MOUSE
NC score	0.077687 (rank : 146)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	213	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

SH21B_MOUSE
NC score	0.077576 (rank : 147)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	213	Target Neighborhood Hits	101	Shared Neighborhood Hits	11
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

BCAR3_MOUSE
NC score	0.077502 (rank : 148)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BASP_HUMAN
NC score	0.076786 (rank : 149)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	213	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SELV_HUMAN
NC score	0.076534 (rank : 150)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	213	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SYN1_MOUSE
NC score	0.076527 (rank : 151)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	213	Target Neighborhood Hits	363	Shared Neighborhood Hits	81
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

RIN2_HUMAN
NC score	0.076518 (rank : 152)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	213	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

SHC3_HUMAN
NC score	0.076344 (rank : 153)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	213	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SC24A_MOUSE
NC score	0.076301 (rank : 154)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	213	Target Neighborhood Hits	394	Shared Neighborhood Hits	53
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

K1802_HUMAN
NC score	0.075793 (rank : 155)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	213	Target Neighborhood Hits	1378	Shared Neighborhood Hits	93
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASF1_HUMAN
NC score	0.075717 (rank : 156)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	82
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

BSN_HUMAN
NC score	0.075608 (rank : 157)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	213	Target Neighborhood Hits	1537	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GAK5_HUMAN
NC score	0.075598 (rank : 158)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	213	Target Neighborhood Hits	429	Shared Neighborhood Hits	38
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

DAPP1_HUMAN
NC score	0.075583 (rank : 159)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ECM1_MOUSE
NC score	0.075553 (rank : 160)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	213	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

K1543_MOUSE
NC score	0.075538 (rank : 161)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	213	Target Neighborhood Hits	497	Shared Neighborhood Hits	50
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

BRD4_HUMAN
NC score	0.075523 (rank : 162)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	213	Target Neighborhood Hits	851	Shared Neighborhood Hits	104
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MLL3_MOUSE
NC score	0.075358 (rank : 163)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	213	Target Neighborhood Hits	1399	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LNK_HUMAN
NC score	0.075327 (rank : 164)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	213	Target Neighborhood Hits	151	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

CIC_HUMAN
NC score	0.075301 (rank : 165)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	213	Target Neighborhood Hits	992	Shared Neighborhood Hits	99
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GRAP_MOUSE
NC score	0.075126 (rank : 166)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	213	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

CBP_HUMAN
NC score	0.075074 (rank : 167)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	213	Target Neighborhood Hits	941	Shared Neighborhood Hits	88
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MDC1_MOUSE
NC score	0.075040 (rank : 168)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	213	Target Neighborhood Hits	998	Shared Neighborhood Hits	69
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

HSH2D_MOUSE
NC score	0.075015 (rank : 169)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	213	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

BCAR3_HUMAN
NC score	0.075009 (rank : 170)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	213	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BAT3_MOUSE
NC score	0.074965 (rank : 171)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	213	Target Neighborhood Hits	518	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CEND1_MOUSE
NC score	0.074948 (rank : 172)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

ALEX_HUMAN
NC score	0.074924 (rank : 173)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	213	Target Neighborhood Hits	361	Shared Neighborhood Hits	65
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GAK4_HUMAN
NC score	0.074776 (rank : 174)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	213	Target Neighborhood Hits	415	Shared Neighborhood Hits	38
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MUC2_HUMAN
NC score	0.074760 (rank : 175)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	213	Target Neighborhood Hits	906	Shared Neighborhood Hits	81
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

IQEC2_MOUSE
NC score	0.074738 (rank : 176)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	213	Target Neighborhood Hits	417	Shared Neighborhood Hits	88
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

GAK11_HUMAN
NC score	0.074736 (rank : 177)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	38
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CS007_MOUSE
NC score	0.074428 (rank : 178)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	213	Target Neighborhood Hits	464	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

GAK2_HUMAN
NC score	0.074048 (rank : 179)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	213	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SYNJ1_HUMAN
NC score	0.073917 (rank : 180)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	213	Target Neighborhood Hits	498	Shared Neighborhood Hits	91
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BASP_MOUSE
NC score	0.073821 (rank : 181)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

LCP2_MOUSE
NC score	0.073811 (rank : 182)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	213	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TAU_HUMAN
NC score	0.073428 (rank : 183)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	213	Target Neighborhood Hits	448	Shared Neighborhood Hits	52
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NCK1_HUMAN
NC score	0.073347 (rank : 184)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	213	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

GRAP2_HUMAN
NC score	0.073234 (rank : 185)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	213	Target Neighborhood Hits	304	Shared Neighborhood Hits	13
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

FMN1A_MOUSE
NC score	0.073085 (rank : 186)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	213	Target Neighborhood Hits	423	Shared Neighborhood Hits	80
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

GAB1_HUMAN
NC score	0.072767 (rank : 187)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	213	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MDC1_HUMAN
NC score	0.072729 (rank : 188)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	213	Target Neighborhood Hits	1446	Shared Neighborhood Hits	80
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CRKL_HUMAN
NC score	0.072686 (rank : 189)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	213	Target Neighborhood Hits	313	Shared Neighborhood Hits	13
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

SYNJ1_MOUSE
NC score	0.072189 (rank : 190)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	213	Target Neighborhood Hits	516	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

GAK12_HUMAN
NC score	0.072139 (rank : 191)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	213	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

DAPP1_MOUSE
NC score	0.072118 (rank : 192)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	213	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SHC1_HUMAN
NC score	0.072115 (rank : 193)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SMR3B_HUMAN
NC score	0.072114 (rank : 194)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	213	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

MUCDL_HUMAN
NC score	0.071539 (rank : 195)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	213	Target Neighborhood Hits	777	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MARCS_HUMAN
NC score	0.071422 (rank : 196)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	213	Target Neighborhood Hits	204	Shared Neighborhood Hits	25
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

SRRM2_MOUSE
NC score	0.071210 (rank : 197)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	213	Target Neighborhood Hits	1470	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.071180 (rank : 198)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	213	Target Neighborhood Hits	1296	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

EP300_HUMAN
NC score	0.070841 (rank : 199)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	213	Target Neighborhood Hits	821	Shared Neighborhood Hits	104
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PO121_HUMAN
NC score	0.070672 (rank : 200)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	213	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CNKR2_MOUSE
NC score	0.070644 (rank : 201)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	213	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.070606 (rank : 202)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	213	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

MNT_HUMAN
NC score	0.070581 (rank : 203)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	213	Target Neighborhood Hits	496	Shared Neighborhood Hits	67
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RTKN_HUMAN
NC score	0.070373 (rank : 204)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	213	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

NCK2_HUMAN
NC score	0.070066 (rank : 205)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOR2_HUMAN
NC score	0.069398 (rank : 206)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	213	Target Neighborhood Hits	870	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CRKL_MOUSE
NC score	0.069173 (rank : 207)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	213	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

MTSS1_MOUSE
NC score	0.069141 (rank : 208)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	213	Target Neighborhood Hits	592	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NCOA6_HUMAN
NC score	0.068992 (rank : 209)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	213	Target Neighborhood Hits	1202	Shared Neighborhood Hits	102
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TM108_MOUSE
NC score	0.068775 (rank : 210)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	213	Target Neighborhood Hits	336	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

BAG3_HUMAN
NC score	0.068531 (rank : 211)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	213	Target Neighborhood Hits	314	Shared Neighborhood Hits	52
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

3BP1_HUMAN
NC score	0.068503 (rank : 212)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	213	Target Neighborhood Hits	376	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TCOF_MOUSE
NC score	0.068256 (rank : 213)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	213	Target Neighborhood Hits	471	Shared Neighborhood Hits	38
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

SHC1_MOUSE
NC score	0.068200 (rank : 214)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	213	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

CBP_MOUSE
NC score	0.068083 (rank : 215)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	213	Target Neighborhood Hits	1051	Shared Neighborhood Hits	92
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SGIP1_HUMAN
NC score	0.067358 (rank : 216)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	213	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

WBS14_HUMAN
NC score	0.067200 (rank : 217)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	213	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

GAK6_HUMAN
NC score	0.067075 (rank : 218)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	213	Target Neighborhood Hits	392	Shared Neighborhood Hits	34
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

AP180_MOUSE
NC score	0.067009 (rank : 219)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	213	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

CIC_MOUSE
NC score	0.066982 (rank : 220)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	213	Target Neighborhood Hits	742	Shared Neighborhood Hits	86
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GRAP2_MOUSE
NC score	0.066952 (rank : 221)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	213	Target Neighborhood Hits	297	Shared Neighborhood Hits	13
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

APS_MOUSE
NC score	0.066920 (rank : 222)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	213	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

DGKK_HUMAN
NC score	0.066865 (rank : 223)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	213	Target Neighborhood Hits	378	Shared Neighborhood Hits	66
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_HUMAN
NC score	0.066766 (rank : 224)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	213	Target Neighborhood Hits	784	Shared Neighborhood Hits	91
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

WASF3_HUMAN
NC score	0.066151 (rank : 225)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	213	Target Neighborhood Hits	204	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

PLCG1_HUMAN
NC score	0.065859 (rank : 226)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	213	Target Neighborhood Hits	293	Shared Neighborhood Hits	17
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
NC score	0.065835 (rank : 227)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	213	Target Neighborhood Hits	314	Shared Neighborhood Hits	17
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

NUMBL_HUMAN
NC score	0.065823 (rank : 228)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	213	Target Neighborhood Hits	394	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

MNT_MOUSE
NC score	0.065556 (rank : 229)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	213	Target Neighborhood Hits	432	Shared Neighborhood Hits	60
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

EFS_HUMAN
NC score	0.065519 (rank : 230)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	213	Target Neighborhood Hits	348	Shared Neighborhood Hits	41
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

GAK1_HUMAN
NC score	0.065458 (rank : 231)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	213	Target Neighborhood Hits	268	Shared Neighborhood Hits	25
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NFH_MOUSE
NC score	0.065242 (rank : 232)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	213	Target Neighborhood Hits	2247	Shared Neighborhood Hits	98
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TAU_MOUSE
NC score	0.065146 (rank : 233)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	213	Target Neighborhood Hits	502	Shared Neighborhood Hits	47
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

IQEC2_HUMAN
NC score	0.064967 (rank : 234)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	213	Target Neighborhood Hits	403	Shared Neighborhood Hits	85
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

NU214_HUMAN
NC score	0.064905 (rank : 235)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	213	Target Neighborhood Hits	657	Shared Neighborhood Hits	53
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RU1C_MOUSE
NC score	0.064728 (rank : 236)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	213	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

CD2_HUMAN
NC score	0.064648 (rank : 237)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	213	Target Neighborhood Hits	504	Shared Neighborhood Hits	47
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

PLCG2_HUMAN
NC score	0.064605 (rank : 238)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	213	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

SGIP1_MOUSE
NC score	0.064564 (rank : 239)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	213	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CTDP1_HUMAN
NC score	0.064463 (rank : 240)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	213	Target Neighborhood Hits	416	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

SELPL_MOUSE
NC score	0.064391 (rank : 241)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	213	Target Neighborhood Hits	588	Shared Neighborhood Hits	50
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RU1C_HUMAN
NC score	0.064331 (rank : 242)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

NCOR2_MOUSE
NC score	0.064251 (rank : 243)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	213	Target Neighborhood Hits	790	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PSL1_HUMAN
NC score	0.064001 (rank : 244)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	213	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

DIAP1_MOUSE
NC score	0.063777 (rank : 245)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	213	Target Neighborhood Hits	839	Shared Neighborhood Hits	79
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

BAT3_HUMAN
NC score	0.063665 (rank : 246)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	213	Target Neighborhood Hits	490	Shared Neighborhood Hits	53
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

NELFA_MOUSE
NC score	0.063388 (rank : 247)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	213	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

HSH2D_HUMAN
NC score	0.063285 (rank : 248)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	213	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

PRCC_HUMAN
NC score	0.062948 (rank : 249)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

NCOA6_MOUSE
NC score	0.062744 (rank : 250)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	213	Target Neighborhood Hits	1076	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

GRB2_HUMAN
NC score	0.062696 (rank : 251)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	213	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.062676 (rank : 252)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	213	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

CO039_HUMAN
NC score	0.062426 (rank : 253)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	213	Target Neighborhood Hits	264	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MADCA_HUMAN
NC score	0.062292 (rank : 254)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	213	Target Neighborhood Hits	221	Shared Neighborhood Hits	48
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SLAP2_HUMAN
NC score	0.062172 (rank : 255)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	213	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

PKHA4_HUMAN
NC score	0.062110 (rank : 256)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	213	Target Neighborhood Hits	283	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CO039_MOUSE
NC score	0.061871 (rank : 257)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	213	Target Neighborhood Hits	445	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

ALEX_MOUSE
NC score	0.061218 (rank : 258)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	213	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RBM12_MOUSE
NC score	0.061197 (rank : 259)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	213	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

BCAR1_HUMAN
NC score	0.061002 (rank : 260)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	213	Target Neighborhood Hits	554	Shared Neighborhood Hits	59
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

ZIM10_HUMAN
NC score	0.060899 (rank : 261)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	213	Target Neighborhood Hits	577	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

K1683_HUMAN
NC score	0.060470 (rank : 262)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	213	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

FMNL_MOUSE
NC score	0.060144 (rank : 263)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	213	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

EFS_MOUSE
NC score	0.059396 (rank : 264)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	213	Target Neighborhood Hits	389	Shared Neighborhood Hits	34
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

GAK10_HUMAN
NC score	0.059236 (rank : 265)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	213	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CNOT3_HUMAN
NC score	0.059236 (rank : 266)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	213	Target Neighborhood Hits	425	Shared Neighborhood Hits	50
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

AP180_HUMAN
NC score	0.059200 (rank : 267)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	213	Target Neighborhood Hits	183	Shared Neighborhood Hits	30
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

PCQAP_HUMAN
NC score	0.058960 (rank : 268)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	213	Target Neighborhood Hits	549	Shared Neighborhood Hits	61
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PRPE_HUMAN
NC score	0.058680 (rank : 269)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	213	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

SEPT9_HUMAN
NC score	0.058591 (rank : 270)	θ value	0.00509761 (rank : 18)
Query Neighborhood Hits	213	Target Neighborhood Hits	706	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CEND2_HUMAN
NC score	0.058461 (rank : 271)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	213	Target Neighborhood Hits	166	Shared Neighborhood Hits	23
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

GAK7_HUMAN
NC score	0.058280 (rank : 272)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	213	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

PO121_MOUSE
NC score	0.058274 (rank : 273)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	213	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

MAP1A_HUMAN
NC score	0.057849 (rank : 274)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	213	Target Neighborhood Hits	1626	Shared Neighborhood Hits	80
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TROAP_HUMAN
NC score	0.057741 (rank : 275)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	213	Target Neighborhood Hits	258	Shared Neighborhood Hits	37
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

WASF3_MOUSE
NC score	0.057541 (rank : 276)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	213	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

SMR2D_MOUSE
NC score	0.057467 (rank : 277)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	213	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	O35979	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform delta precursor (Salivary protein MSG2, isoform delta).

ARI1A_HUMAN
NC score	0.057280 (rank : 278)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	213	Target Neighborhood Hits	787	Shared Neighborhood Hits	82
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

PDCD7_HUMAN
NC score	0.057159 (rank : 279)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	213	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

NOLC1_HUMAN
NC score	0.057059 (rank : 280)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	213	Target Neighborhood Hits	452	Shared Neighborhood Hits	34
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SSBP4_HUMAN
NC score	0.056864 (rank : 281)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	213	Target Neighborhood Hits	753	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

GAK8_HUMAN
NC score	0.056862 (rank : 282)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	213	Target Neighborhood Hits	145	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PI5PA_HUMAN
NC score	0.056844 (rank : 283)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	213	Target Neighborhood Hits	749	Shared Neighborhood Hits	71
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ZN645_HUMAN
NC score	0.056838 (rank : 284)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	213	Target Neighborhood Hits	265	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

VASP_HUMAN
NC score	0.056772 (rank : 285)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	213	Target Neighborhood Hits	201	Shared Neighborhood Hits	53
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

TMAP1_HUMAN
NC score	0.056747 (rank : 286)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	213	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TCOF_HUMAN
NC score	0.056493 (rank : 287)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	213	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SMR2C_MOUSE
NC score	0.056437 (rank : 288)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	213	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	O35985	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform gamma precursor (Salivary protein MSG2, isoform gamma).

SH2D3_MOUSE
NC score	0.056272 (rank : 289)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	213	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SMRC2_MOUSE
NC score	0.055725 (rank : 290)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	213	Target Neighborhood Hits	487	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PRRT1_MOUSE
NC score	0.055451 (rank : 291)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	213	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

K1543_HUMAN
NC score	0.055276 (rank : 292)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	213	Target Neighborhood Hits	435	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RNC_HUMAN
NC score	0.055219 (rank : 293)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	213	Target Neighborhood Hits	176	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

3BP2_MOUSE
NC score	0.055107 (rank : 294)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	213	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

GAK3_HUMAN
NC score	0.054960 (rank : 295)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	213	Target Neighborhood Hits	182	Shared Neighborhood Hits	19
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GBF1_HUMAN
NC score	0.054722 (rank : 296)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	213	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

SC24D_HUMAN
NC score	0.054656 (rank : 297)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	213	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

MINT_MOUSE
NC score	0.054570 (rank : 298)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	213	Target Neighborhood Hits	1514	Shared Neighborhood Hits	73
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CS007_HUMAN
NC score	0.054413 (rank : 299)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	213	Target Neighborhood Hits	401	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

SPR1B_MOUSE
NC score	0.054328 (rank : 300)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	213	Target Neighborhood Hits	395	Shared Neighborhood Hits	32
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

ATX2L_HUMAN
NC score	0.054259 (rank : 301)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	213	Target Neighborhood Hits	443	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

OGFR_MOUSE
NC score	0.054244 (rank : 302)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	213	Target Neighborhood Hits	584	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

RPB1_MOUSE
NC score	0.053742 (rank : 303)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	213	Target Neighborhood Hits	363	Shared Neighborhood Hits	55
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CHIN_MOUSE
NC score	0.053475 (rank : 304)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	213	Target Neighborhood Hits	229	Shared Neighborhood Hits	14
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

IF4G1_MOUSE
NC score	0.053329 (rank : 305)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	213	Target Neighborhood Hits	534	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

RPB1_HUMAN
NC score	0.053245 (rank : 306)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	213	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CITE4_HUMAN
NC score	0.053126 (rank : 307)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	213	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

MINT_HUMAN
NC score	0.053077 (rank : 308)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	213	Target Neighborhood Hits	1291	Shared Neighborhood Hits	74
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CNKR1_HUMAN
NC score	0.052931 (rank : 309)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	213	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

SHE_MOUSE
NC score	0.052912 (rank : 310)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	213	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

PDC6I_HUMAN
NC score	0.052885 (rank : 311)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	213	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

CHIO_HUMAN
NC score	0.052881 (rank : 312)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	213	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

JPH2_HUMAN
NC score	0.052877 (rank : 313)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	213	Target Neighborhood Hits	639	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SPRR3_HUMAN
NC score	0.052804 (rank : 314)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	213	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

MARCS_MOUSE
NC score	0.052696 (rank : 315)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

F120C_MOUSE
NC score	0.052625 (rank : 316)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	213	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

MAP4_MOUSE
NC score	0.052573 (rank : 317)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	35
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TENS4_HUMAN
NC score	0.052552 (rank : 318)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	213	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

PI5PA_MOUSE
NC score	0.052545 (rank : 319)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	213	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TCGAP_MOUSE
NC score	0.052538 (rank : 320)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SH2D3_HUMAN
NC score	0.052471 (rank : 321)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	213	Target Neighborhood Hits	188	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

NELFA_HUMAN
NC score	0.052290 (rank : 322)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	213	Target Neighborhood Hits	161	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

SLAP2_MOUSE
NC score	0.052205 (rank : 323)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	213	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

PTN11_MOUSE
NC score	0.052041 (rank : 324)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.052034 (rank : 325)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

AUTS2_HUMAN
NC score	0.051787 (rank : 326)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	213	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

PRRT1_HUMAN
NC score	0.051778 (rank : 327)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

BCAR1_MOUSE
NC score	0.051767 (rank : 328)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	213	Target Neighborhood Hits	438	Shared Neighborhood Hits	49
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

IF35_MOUSE
NC score	0.051678 (rank : 329)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	213	Target Neighborhood Hits	210	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

RC3H1_HUMAN
NC score	0.051641 (rank : 330)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	213	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

ZIMP7_MOUSE
NC score	0.051377 (rank : 331)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	213	Target Neighborhood Hits	566	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

RBM12_HUMAN
NC score	0.051091 (rank : 332)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	213	Target Neighborhood Hits	298	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SMRC2_HUMAN
NC score	0.051006 (rank : 333)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	213	Target Neighborhood Hits	499	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

JADE2_MOUSE
NC score	0.050953 (rank : 334)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	213	Target Neighborhood Hits	560	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BLNK_HUMAN
NC score	0.050881 (rank : 335)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	213	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

SHD_MOUSE
NC score	0.050835 (rank : 336)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	213	Target Neighborhood Hits	137	Shared Neighborhood Hits	9
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

CHIN_HUMAN
NC score	0.050659 (rank : 337)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

PDC6I_MOUSE
NC score	0.050126 (rank : 338)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	213	Target Neighborhood Hits	275	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

IQEC3_MOUSE
NC score	0.050043 (rank : 339)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	213	Target Neighborhood Hits	274	Shared Neighborhood Hits	36
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

FGFP3_HUMAN
NC score	0.049831 (rank : 340)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	213	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

CD248_HUMAN
NC score	0.049385 (rank : 341)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	213	Target Neighborhood Hits	679	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GNAS1_MOUSE
NC score	0.048593 (rank : 342)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	213	Target Neighborhood Hits	651	Shared Neighborhood Hits	56
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

LPP_HUMAN
NC score	0.047626 (rank : 343)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	213	Target Neighborhood Hits	775	Shared Neighborhood Hits	57
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MBB1A_HUMAN
NC score	0.047198 (rank : 344)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	213	Target Neighborhood Hits	665	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

RHG25_MOUSE
NC score	0.044740 (rank : 345)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	213	Target Neighborhood Hits	492	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TULP4_HUMAN
NC score	0.044260 (rank : 346)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	213	Target Neighborhood Hits	426	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

URP2_HUMAN
NC score	0.044019 (rank : 347)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	213	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

RP1L1_HUMAN
NC score	0.043704 (rank : 348)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	213	Target Neighborhood Hits	1072	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MKL1_MOUSE
NC score	0.043468 (rank : 349)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	213	Target Neighborhood Hits	667	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NSD1_MOUSE
NC score	0.040762 (rank : 350)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	213	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RBBP6_HUMAN
NC score	0.040359 (rank : 351)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	213	Target Neighborhood Hits	1135	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CD248_MOUSE
NC score	0.039754 (rank : 352)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	213	Target Neighborhood Hits	578	Shared Neighborhood Hits	37
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ATX7_HUMAN
NC score	0.039516 (rank : 353)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	213	Target Neighborhood Hits	351	Shared Neighborhood Hits	34
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

F120C_HUMAN
NC score	0.038721 (rank : 354)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	213	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

CECR2_HUMAN
NC score	0.038044 (rank : 355)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	213	Target Neighborhood Hits	543	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

IWS1_MOUSE
NC score	0.036966 (rank : 356)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	213	Target Neighborhood Hits	1258	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RP3A_MOUSE
NC score	0.036156 (rank : 357)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	213	Target Neighborhood Hits	510	Shared Neighborhood Hits	47
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

URP2_MOUSE
NC score	0.036126 (rank : 358)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	213	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

RHG25_HUMAN
NC score	0.035778 (rank : 359)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	213	Target Neighborhood Hits	550	Shared Neighborhood Hits	30
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SAM14_MOUSE
NC score	0.034867 (rank : 360)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	213	Target Neighborhood Hits	91	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

ANTOL_MOUSE
NC score	0.034770 (rank : 361)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	213	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8N6	Gene names
Domain Architecture	No domain graphic available
Description	Antolefinin (Antolefinine).

HCLS1_HUMAN
NC score	0.034350 (rank : 362)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	213	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ZN687_HUMAN
NC score	0.034072 (rank : 363)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	213	Target Neighborhood Hits	1244	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SAM14_HUMAN
NC score	0.033872 (rank : 364)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

COX10_MOUSE
NC score	0.033457 (rank : 365)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	213	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

PKHA2_HUMAN
NC score	0.033317 (rank : 366)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	213	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

BTBDC_HUMAN
NC score	0.031859 (rank : 367)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	213	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

RASA2_MOUSE
NC score	0.031420 (rank : 368)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	213	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

MYO15_HUMAN
NC score	0.031364 (rank : 369)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	213	Target Neighborhood Hits	671	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

DGKH_HUMAN
NC score	0.030716 (rank : 370)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	213	Target Neighborhood Hits	255	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

LARP1_HUMAN
NC score	0.030351 (rank : 371)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	213	Target Neighborhood Hits	242	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

ACK1_HUMAN
NC score	0.029818 (rank : 372)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	213	Target Neighborhood Hits	1140	Shared Neighborhood Hits	76
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

DOCK4_HUMAN
NC score	0.029799 (rank : 373)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	213	Target Neighborhood Hits	237	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

FOXJ2_HUMAN
NC score	0.029355 (rank : 374)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	213	Target Neighborhood Hits	239	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

CSPG5_HUMAN
NC score	0.029135 (rank : 375)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	213	Target Neighborhood Hits	199	Shared Neighborhood Hits	19
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

ANR11_HUMAN
NC score	0.028370 (rank : 376)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	213	Target Neighborhood Hits	1289	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PRGC2_MOUSE
NC score	0.027152 (rank : 377)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	213	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

DOCK4_MOUSE
NC score	0.027007 (rank : 378)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	213	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

TAF6L_MOUSE
NC score	0.025403 (rank : 379)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	213	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

ACK1_MOUSE
NC score	0.025341 (rank : 380)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	213	Target Neighborhood Hits	1080	Shared Neighborhood Hits	65
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

YTHD2_HUMAN
NC score	0.025071 (rank : 381)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	213	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

COA2_HUMAN
NC score	0.024929 (rank : 382)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	213	Target Neighborhood Hits	184	Shared Neighborhood Hits	13
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

FOXN1_MOUSE
NC score	0.024629 (rank : 383)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	213	Target Neighborhood Hits	300	Shared Neighborhood Hits	25
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

AATK_HUMAN
NC score	0.024280 (rank : 384)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	213	Target Neighborhood Hits	1243	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

SNPC4_MOUSE
NC score	0.023752 (rank : 385)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	213	Target Neighborhood Hits	237	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

BCLF1_HUMAN
NC score	0.023544 (rank : 386)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	213	Target Neighborhood Hits	298	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

FXL19_MOUSE
NC score	0.023513 (rank : 387)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	213	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

NADAP_HUMAN
NC score	0.022742 (rank : 388)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	213	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

NECD_MOUSE
NC score	0.022652 (rank : 389)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	213	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

RUNX3_HUMAN
NC score	0.022351 (rank : 390)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	213	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

GR65_MOUSE
NC score	0.021988 (rank : 391)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	213	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q91X51, Q9D3L9	Gene names	Gorasp1
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65).

IF4B_MOUSE
NC score	0.021829 (rank : 392)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	213	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

NLGN3_HUMAN
NC score	0.021394 (rank : 393)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

TLN1_HUMAN
NC score	0.020792 (rank : 394)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	213	Target Neighborhood Hits	218	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

SCAP_HUMAN
NC score	0.020774 (rank : 395)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	213	Target Neighborhood Hits	368	Shared Neighborhood Hits	16
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

RUNX2_MOUSE
NC score	0.020184 (rank : 396)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	213	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_HUMAN
NC score	0.020097 (rank : 397)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	213	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

ZN438_HUMAN
NC score	0.018010 (rank : 398)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	213	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

FOXN4_HUMAN
NC score	0.017969 (rank : 399)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	213	Target Neighborhood Hits	248	Shared Neighborhood Hits	15
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

RAD9A_MOUSE
NC score	0.016117 (rank : 400)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	213	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0F6, Q8QZZ3	Gene names	Rad9a, Rad9
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (Rad9-like protein) (mRAD9).

GP112_HUMAN
NC score	0.015817 (rank : 401)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	213	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

P2RX2_HUMAN
NC score	0.015775 (rank : 402)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	213	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

Z3H7A_HUMAN
NC score	0.015396 (rank : 403)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	213	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

GGA3_HUMAN
NC score	0.015214 (rank : 404)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

MAGI2_MOUSE
NC score	0.014932 (rank : 405)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	213	Target Neighborhood Hits	370	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

RASL1_MOUSE
NC score	0.013944 (rank : 406)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

BLK_HUMAN
NC score	0.013141 (rank : 407)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	213	Target Neighborhood Hits	994	Shared Neighborhood Hits	19
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

TRIP6_HUMAN
NC score	0.012740 (rank : 408)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	213	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

GGA1_HUMAN
NC score	0.012659 (rank : 409)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	213	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

STMN1_MOUSE
NC score	0.012561 (rank : 410)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	213	Target Neighborhood Hits	560	Shared Neighborhood Hits	13
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

LGMN_HUMAN
NC score	0.012287 (rank : 411)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	213	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q99538, O00123	Gene names	LGMN, PRSC1
Domain Architecture
Description	Legumain precursor (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1).

RM19_HUMAN
NC score	0.011912 (rank : 412)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	213	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P49406, Q53TX9	Gene names	MRPL19, KIAA0104
Domain Architecture
Description	39S ribosomal protein L19, mitochondrial precursor (L19mt) (MRP-L19) (MRP-L15).

PALB2_HUMAN
NC score	0.011756 (rank : 413)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	213	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

LAEVR_HUMAN
NC score	0.011576 (rank : 414)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	213	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

NOS3_MOUSE
NC score	0.011378 (rank : 415)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	213	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

KLF17_HUMAN
NC score	0.010842 (rank : 416)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	213	Target Neighborhood Hits	882	Shared Neighborhood Hits	34
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

INVS_MOUSE
NC score	0.010010 (rank : 417)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	213	Target Neighborhood Hits	609	Shared Neighborhood Hits	32
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

RX_MOUSE
NC score	0.009265 (rank : 418)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	213	Target Neighborhood Hits	429	Shared Neighborhood Hits	15
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TSC1_HUMAN
NC score	0.009012 (rank : 419)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	213	Target Neighborhood Hits	765	Shared Neighborhood Hits	15
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ULK1_MOUSE
NC score	0.008934 (rank : 420)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	213	Target Neighborhood Hits	1214	Shared Neighborhood Hits	40
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ANK3_HUMAN
NC score	0.008837 (rank : 421)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	213	Target Neighborhood Hits	853	Shared Neighborhood Hits	34
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

SL9A9_HUMAN
NC score	0.008323 (rank : 422)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	213	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVB4, Q8NAB9	Gene names	SLC9A9, NHE9
Domain Architecture
Description	Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9).

TMG1_HUMAN
NC score	0.008293 (rank : 423)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	213	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

CAC1B_MOUSE
NC score	0.007936 (rank : 424)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	213	Target Neighborhood Hits	351	Shared Neighborhood Hits	19
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SL9A2_HUMAN
NC score	0.007827 (rank : 425)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBY0	Gene names	SLC9A2, NHE2
Domain Architecture
Description	Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2).

GLIS3_MOUSE
NC score	0.007418 (rank : 426)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	213	Target Neighborhood Hits	861	Shared Neighborhood Hits	30
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

INADL_HUMAN
NC score	0.007402 (rank : 427)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	213	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

ERBB2_HUMAN
NC score	0.006901 (rank : 428)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	213	Target Neighborhood Hits	1073	Shared Neighborhood Hits	22
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

PO2F2_HUMAN
NC score	0.006890 (rank : 429)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	213	Target Neighborhood Hits	379	Shared Neighborhood Hits	16
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

GLTL1_MOUSE
NC score	0.006602 (rank : 430)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	213	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ61	Gene names	Galntl1
Domain Architecture	No domain graphic available
Description	Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase- like protein 1) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1).

ZN142_HUMAN
NC score	0.006536 (rank : 431)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	213	Target Neighborhood Hits	1007	Shared Neighborhood Hits	46
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

MRP2_HUMAN
NC score	0.006354 (rank : 432)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	213	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

GALT1_HUMAN
NC score	0.005847 (rank : 433)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	213	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q10472, Q86TJ7, Q9UM86	Gene names	GALNT1
Domain Architecture
Description	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) [Contains: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form].

EGR1_MOUSE
NC score	0.005371 (rank : 434)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	213	Target Neighborhood Hits	816	Shared Neighborhood Hits	33
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

KCNQ5_HUMAN
NC score	0.005285 (rank : 435)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	213	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

GLI2_HUMAN
NC score	0.005252 (rank : 436)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	213	Target Neighborhood Hits	971	Shared Neighborhood Hits	32
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

SALL2_MOUSE
NC score	0.005085 (rank : 437)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	213	Target Neighborhood Hits	836	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

RIPK3_MOUSE
NC score	0.004759 (rank : 438)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	213	Target Neighborhood Hits	867	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

TBX22_MOUSE
NC score	0.004203 (rank : 439)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	213	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

EGR4_HUMAN
NC score	0.003893 (rank : 440)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	213	Target Neighborhood Hits	939	Shared Neighborhood Hits	33
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

SP7_MOUSE
NC score	0.003537 (rank : 441)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	213	Target Neighborhood Hits	756	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

SP7_HUMAN
NC score	0.002838 (rank : 442)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	213	Target Neighborhood Hits	734	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

KIF25_HUMAN
NC score	0.002713 (rank : 443)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	213	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIL4, O94775	Gene names	KIF25, KNSL3
Domain Architecture
Description	Kinesin-like protein KIF25 (Kinesin-like protein 3).

MTR1L_HUMAN
NC score	0.001151 (rank : 444)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	213	Target Neighborhood Hits	1180	Shared Neighborhood Hits	24
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

SM1L2_MOUSE
NC score	-0.000044 (rank : 445)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	213	Target Neighborhood Hits	918	Shared Neighborhood Hits	10
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

ZN467_MOUSE
NC score	-0.000163 (rank : 446)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	213	Target Neighborhood Hits	794	Shared Neighborhood Hits	15
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

CDKL5_HUMAN
NC score	-0.000392 (rank : 447)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	213	Target Neighborhood Hits	967	Shared Neighborhood Hits	19
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CTRO_MOUSE
NC score	-0.001503 (rank : 448)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	213	Target Neighborhood Hits	2344	Shared Neighborhood Hits	37
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).