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Network neighborhood for query Sequence : LAEVR_HUMAN

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LAEVR_HUMAN
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LAEVR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

LAEVR_MOUSE
θ value	0 (rank : 2)	NC score	0.989426 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q2KHK3, Q9D633	Gene names	Lvrn
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-).

AMPN_MOUSE
θ value	7.76955e-161 (rank : 3)	NC score	0.976834 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	P97449, Q91YH8, Q99K63	Gene names	Anpep, Lap-1, Lap1
Domain Architecture
Description	Aminopeptidase N (EC 3.4.11.2) (mAPN) (Alanyl aminopeptidase) (Microsomal aminopeptidase) (Aminopeptidase M) (Membrane protein p161) (CD13 antigen).

AMPN_HUMAN
θ value	2.95243e-160 (rank : 4)	NC score	0.976556 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P15144, Q16728, Q8IUK3, Q8IVH3, Q9UCE0	Gene names	ANPEP, APN, CD13, PEPN
Domain Architecture
Description	Aminopeptidase N (EC 3.4.11.2) (hAPN) (Alanyl aminopeptidase) (Microsomal aminopeptidase) (Aminopeptidase M) (gp150) (Myeloid plasma membrane glycoprotein CD13) (CD13 antigen).

TRHDE_MOUSE
θ value	3.1838e-130 (rank : 5)	NC score	0.964362 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K093	Gene names	Trhde
Domain Architecture	No domain graphic available
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TRHDE_HUMAN
θ value	3.5201e-129 (rank : 6)	NC score	0.965564 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

AMPE_HUMAN
θ value	2.14053e-118 (rank : 7)	NC score	0.963031 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q07075	Gene names	ENPEP
Domain Architecture
Description	Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (Differentiation antigen gp160) (CD249 antigen).

ARTS1_MOUSE
θ value	2.9938e-112 (rank : 8)	NC score	0.961569 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EQH2, Q9ET63	Gene names	Arts1, Appils
Domain Architecture
Description	Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A- LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl- specific aminopeptidase) (PILS-AP) (VEGF-induced aminopeptidase).

AMPE_MOUSE
θ value	5.10665e-112 (rank : 9)	NC score	0.961870 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	P16406	Gene names	Enpep
Domain Architecture
Description	Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (BP-1/6C3 antigen).

ARTS1_HUMAN
θ value	3.65967e-110 (rank : 10)	NC score	0.960768 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZ08, O60278, Q6UWY6, Q8NEL4, Q8TAD0, Q9UHF8, Q9UKY2	Gene names	ARTS1, APPILS, KIAA0525
Domain Architecture
Description	Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A- LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl- specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator).

LCAP_HUMAN
θ value	2.62879e-100 (rank : 11)	NC score	0.961729 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIQ6, O00769, Q15145, Q9UIQ7	Gene names	LNPEP, OTASE
Domain Architecture
Description	Leucyl-cystinyl aminopeptidase (EC 3.4.11.3) (Cystinyl aminopeptidase) (Oxytocinase) (OTase) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Placental leucine aminopeptidase) (P-LAP).

PSA_HUMAN
θ value	3.0217e-80 (rank : 12)	NC score	0.946002 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	P55786, Q6P145, Q9NP16, Q9UEM2	Gene names	NPEPPS, PSA
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

PSA_MOUSE
θ value	5.15425e-80 (rank : 13)	NC score	0.945991 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	Q11011, Q91VJ8	Gene names	Npepps, Psa
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

LKHA4_MOUSE
θ value	2.20094e-22 (rank : 14)	NC score	0.716177 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	P24527, Q8VDR8	Gene names	Lta4h
Domain Architecture
Description	Leukotriene A-4 hydrolase (EC 3.3.2.6) (LTA-4 hydrolase) (Leukotriene A(4) hydrolase).

LKHA4_HUMAN
θ value	4.15078e-21 (rank : 15)	NC score	0.723501 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P09960	Gene names	LTA4H, LTA4
Domain Architecture
Description	Leukotriene A-4 hydrolase (EC 3.3.2.6) (LTA-4 hydrolase) (Leukotriene A(4) hydrolase).

AMPB_MOUSE
θ value	1.02238e-19 (rank : 16)	NC score	0.681396 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCT3	Gene names	Rnpep
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase) (Cytosol aminopeptidase IV).

AMPB_HUMAN
θ value	1.52774e-15 (rank : 17)	NC score	0.668807 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H4A4, Q9BVM9, Q9H1D4, Q9NPT7	Gene names	RNPEP, APB
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase).

RNPL1_HUMAN
θ value	6.00763e-12 (rank : 18)	NC score	0.647211 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HAU8, Q96AC9, Q9H033, Q9NVD0	Gene names	RNPEPL1
Domain Architecture
Description	Arginyl aminopeptidase-like 1 (EC 3.4.11.-) (RNPEP-like protein).

AMPO_HUMAN
θ value	2.44474e-05 (rank : 19)	NC score	0.461076 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N6M6, Q5T9B1, Q5T9B3, Q5T9B4, Q8WUL6, Q96M23, Q96SS1	Gene names	ONPEP, C9orf3
Domain Architecture	No domain graphic available
Description	Aminopeptidase O (EC 3.4.11.-) (AP-O).

AMPO_MOUSE
θ value	4.1701e-05 (rank : 20)	NC score	0.446060 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BXQ6, Q6P0W6, Q6P394, Q8BHX5	Gene names	Onpep
Domain Architecture	No domain graphic available
Description	Aminopeptidase O (EC 3.4.11.-) (AP-O).

MYO15_MOUSE
θ value	0.0431538 (rank : 21)	NC score	0.013255 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

BAT2_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.031454 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	947	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

M4K1_HUMAN
θ value	0.47712 (rank : 23)	NC score	-0.000135 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	884	Shared Neighborhood Hits	3
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

BIN1_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.019594 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	335	Shared Neighborhood Hits	14
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

ITSN1_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.008377 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	1757	Shared Neighborhood Hits	28
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.008073 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	1669	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CU030_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.037672 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

IGS4B_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.011131 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	328	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

RD23B_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.018828 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	189	Shared Neighborhood Hits	8
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

BAT2_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.026992 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	931	Shared Neighborhood Hits	25
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EP300_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.012165 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	821	Shared Neighborhood Hits	16
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PELP1_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.018700 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	709	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

WASIP_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.020108 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PRR12_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.021633 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	460	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SRRM2_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.015123 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	1296	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MUC2_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.009246 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RGS3_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.009736 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1375	Shared Neighborhood Hits	34
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

AB1IP_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.011576 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

SPT5H_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.016537 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	436	Shared Neighborhood Hits	21
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

TREF1_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.008298 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	682	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

HXA3_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.002615 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	558	Shared Neighborhood Hits	10
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

SRRM2_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.012729 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

UBP43_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.006953 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

CENG1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.003986 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	544	Shared Neighborhood Hits	6
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DYR1B_MOUSE
θ value	4.03905 (rank : 45)	NC score	-0.001121 (rank : 75)
Query Neighborhood Hits	73	Target Neighborhood Hits	799	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

FGD1_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.006521 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MLL4_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.007951 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	722	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PCLO_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.006976 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	2275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ADA12_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.001814 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	224	Shared Neighborhood Hits	2
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CASL_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.008735 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CN032_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.012600 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

DDEF2_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.006378 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	599	Shared Neighborhood Hits	15
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

IRS2_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.008337 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MTLR_HUMAN
θ value	5.27518 (rank : 54)	NC score	-0.000926 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	796	Shared Neighborhood Hits	2
SwissProt Accessions	O43193	Gene names	MLNR, GPR38, MTLR, MTLR1
Domain Architecture
Description	Motilin receptor (G-protein coupled receptor 38).

SF3A1_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.014823 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.015146 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

CNTP1_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.003601 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

COHA1_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.004713 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	414	Shared Neighborhood Hits	11
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ES8L3_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.006737 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FMNL_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.007210 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	529	Shared Neighborhood Hits	12
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GCS1_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.009297 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UM7, Q9Z2W5	Gene names	Gcs1
Domain Architecture
Description	Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glycoprotein- processing glucosidase I) (Glucosidase 1).

IGS4B_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.007460 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

LDB3_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.002653 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	510	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PTN23_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.003959 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	726	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SF3B3_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.010700 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

SYN2_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.007824 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

TARA_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.006366 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ABI3_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.007381 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ASPP2_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.001375 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	1156	Shared Neighborhood Hits	16
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

FREA_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.001547 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

MNT_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.006828 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	432	Shared Neighborhood Hits	13
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SET1A_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.007057 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	690	Shared Neighborhood Hits	13
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ZYX_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.003446 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	347	Shared Neighborhood Hits	10
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

TAF2_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.161782 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P1X5, O43487, O43604, O60668, Q86WW7, Q8IWK4	Gene names	TAF2, CIF150, TAF2B
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (TBP-associated factor 150 kDa) (TAFII-150) (TAFII150) (150 kDa cofactor of initiator function).

TAF2_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.153786 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C176, Q8BKQ7	Gene names	Taf2
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (TBP-associated factor 150 kDa).

Hits sorted by NC score

LAEVR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

LAEVR_MOUSE
NC score	0.989426 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q2KHK3, Q9D633	Gene names	Lvrn
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-).

AMPN_MOUSE
NC score	0.976834 (rank : 3)	θ value	7.76955e-161 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	P97449, Q91YH8, Q99K63	Gene names	Anpep, Lap-1, Lap1
Domain Architecture
Description	Aminopeptidase N (EC 3.4.11.2) (mAPN) (Alanyl aminopeptidase) (Microsomal aminopeptidase) (Aminopeptidase M) (Membrane protein p161) (CD13 antigen).

AMPN_HUMAN
NC score	0.976556 (rank : 4)	θ value	2.95243e-160 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P15144, Q16728, Q8IUK3, Q8IVH3, Q9UCE0	Gene names	ANPEP, APN, CD13, PEPN
Domain Architecture
Description	Aminopeptidase N (EC 3.4.11.2) (hAPN) (Alanyl aminopeptidase) (Microsomal aminopeptidase) (Aminopeptidase M) (gp150) (Myeloid plasma membrane glycoprotein CD13) (CD13 antigen).

TRHDE_HUMAN
NC score	0.965564 (rank : 5)	θ value	3.5201e-129 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TRHDE_MOUSE
NC score	0.964362 (rank : 6)	θ value	3.1838e-130 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K093	Gene names	Trhde
Domain Architecture	No domain graphic available
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

AMPE_HUMAN
NC score	0.963031 (rank : 7)	θ value	2.14053e-118 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q07075	Gene names	ENPEP
Domain Architecture
Description	Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (Differentiation antigen gp160) (CD249 antigen).

AMPE_MOUSE
NC score	0.961870 (rank : 8)	θ value	5.10665e-112 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	P16406	Gene names	Enpep
Domain Architecture
Description	Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (BP-1/6C3 antigen).

LCAP_HUMAN
NC score	0.961729 (rank : 9)	θ value	2.62879e-100 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIQ6, O00769, Q15145, Q9UIQ7	Gene names	LNPEP, OTASE
Domain Architecture
Description	Leucyl-cystinyl aminopeptidase (EC 3.4.11.3) (Cystinyl aminopeptidase) (Oxytocinase) (OTase) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Placental leucine aminopeptidase) (P-LAP).

ARTS1_MOUSE
NC score	0.961569 (rank : 10)	θ value	2.9938e-112 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EQH2, Q9ET63	Gene names	Arts1, Appils
Domain Architecture
Description	Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A- LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl- specific aminopeptidase) (PILS-AP) (VEGF-induced aminopeptidase).

ARTS1_HUMAN
NC score	0.960768 (rank : 11)	θ value	3.65967e-110 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZ08, O60278, Q6UWY6, Q8NEL4, Q8TAD0, Q9UHF8, Q9UKY2	Gene names	ARTS1, APPILS, KIAA0525
Domain Architecture
Description	Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A- LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl- specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator).

PSA_HUMAN
NC score	0.946002 (rank : 12)	θ value	3.0217e-80 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	P55786, Q6P145, Q9NP16, Q9UEM2	Gene names	NPEPPS, PSA
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

PSA_MOUSE
NC score	0.945991 (rank : 13)	θ value	5.15425e-80 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	Q11011, Q91VJ8	Gene names	Npepps, Psa
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

LKHA4_HUMAN
NC score	0.723501 (rank : 14)	θ value	4.15078e-21 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P09960	Gene names	LTA4H, LTA4
Domain Architecture
Description	Leukotriene A-4 hydrolase (EC 3.3.2.6) (LTA-4 hydrolase) (Leukotriene A(4) hydrolase).

LKHA4_MOUSE
NC score	0.716177 (rank : 15)	θ value	2.20094e-22 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	P24527, Q8VDR8	Gene names	Lta4h
Domain Architecture
Description	Leukotriene A-4 hydrolase (EC 3.3.2.6) (LTA-4 hydrolase) (Leukotriene A(4) hydrolase).

AMPB_MOUSE
NC score	0.681396 (rank : 16)	θ value	1.02238e-19 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCT3	Gene names	Rnpep
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase) (Cytosol aminopeptidase IV).

AMPB_HUMAN
NC score	0.668807 (rank : 17)	θ value	1.52774e-15 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H4A4, Q9BVM9, Q9H1D4, Q9NPT7	Gene names	RNPEP, APB
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase).

RNPL1_HUMAN
NC score	0.647211 (rank : 18)	θ value	6.00763e-12 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HAU8, Q96AC9, Q9H033, Q9NVD0	Gene names	RNPEPL1
Domain Architecture
Description	Arginyl aminopeptidase-like 1 (EC 3.4.11.-) (RNPEP-like protein).

AMPO_HUMAN
NC score	0.461076 (rank : 19)	θ value	2.44474e-05 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N6M6, Q5T9B1, Q5T9B3, Q5T9B4, Q8WUL6, Q96M23, Q96SS1	Gene names	ONPEP, C9orf3
Domain Architecture	No domain graphic available
Description	Aminopeptidase O (EC 3.4.11.-) (AP-O).

AMPO_MOUSE
NC score	0.446060 (rank : 20)	θ value	4.1701e-05 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BXQ6, Q6P0W6, Q6P394, Q8BHX5	Gene names	Onpep
Domain Architecture	No domain graphic available
Description	Aminopeptidase O (EC 3.4.11.-) (AP-O).

TAF2_HUMAN
NC score	0.161782 (rank : 21)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P1X5, O43487, O43604, O60668, Q86WW7, Q8IWK4	Gene names	TAF2, CIF150, TAF2B
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (TBP-associated factor 150 kDa) (TAFII-150) (TAFII150) (150 kDa cofactor of initiator function).

TAF2_MOUSE
NC score	0.153786 (rank : 22)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C176, Q8BKQ7	Gene names	Taf2
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (TBP-associated factor 150 kDa).

CU030_HUMAN
NC score	0.037672 (rank : 23)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

BAT2_MOUSE
NC score	0.031454 (rank : 24)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	947	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_HUMAN
NC score	0.026992 (rank : 25)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	931	Shared Neighborhood Hits	25
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRR12_HUMAN
NC score	0.021633 (rank : 26)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	460	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

WASIP_MOUSE
NC score	0.020108 (rank : 27)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

BIN1_HUMAN
NC score	0.019594 (rank : 28)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	335	Shared Neighborhood Hits	14
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

RD23B_MOUSE
NC score	0.018828 (rank : 29)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	189	Shared Neighborhood Hits	8
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PELP1_MOUSE
NC score	0.018700 (rank : 30)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	709	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SPT5H_HUMAN
NC score	0.016537 (rank : 31)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	436	Shared Neighborhood Hits	21
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SF3A1_MOUSE
NC score	0.015146 (rank : 32)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SRRM2_HUMAN
NC score	0.015123 (rank : 33)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	1296	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SF3A1_HUMAN
NC score	0.014823 (rank : 34)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

MYO15_MOUSE
NC score	0.013255 (rank : 35)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SRRM2_MOUSE
NC score	0.012729 (rank : 36)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CN032_HUMAN
NC score	0.012600 (rank : 37)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

EP300_HUMAN
NC score	0.012165 (rank : 38)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	821	Shared Neighborhood Hits	16
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

AB1IP_HUMAN
NC score	0.011576 (rank : 39)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

IGS4B_MOUSE
NC score	0.011131 (rank : 40)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	328	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

SF3B3_HUMAN
NC score	0.010700 (rank : 41)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

RGS3_HUMAN
NC score	0.009736 (rank : 42)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	1375	Shared Neighborhood Hits	34
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GCS1_MOUSE
NC score	0.009297 (rank : 43)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UM7, Q9Z2W5	Gene names	Gcs1
Domain Architecture
Description	Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glycoprotein- processing glucosidase I) (Glucosidase 1).

MUC2_HUMAN
NC score	0.009246 (rank : 44)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CASL_MOUSE
NC score	0.008735 (rank : 45)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

ITSN1_HUMAN
NC score	0.008377 (rank : 46)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	1757	Shared Neighborhood Hits	28
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

IRS2_HUMAN
NC score	0.008337 (rank : 47)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

TREF1_MOUSE
NC score	0.008298 (rank : 48)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	682	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

ITSN1_MOUSE
NC score	0.008073 (rank : 49)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	1669	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MLL4_HUMAN
NC score	0.007951 (rank : 50)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	722	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SYN2_MOUSE
NC score	0.007824 (rank : 51)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

IGS4B_HUMAN
NC score	0.007460 (rank : 52)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

ABI3_HUMAN
NC score	0.007381 (rank : 53)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

FMNL_HUMAN
NC score	0.007210 (rank : 54)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	529	Shared Neighborhood Hits	12
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

SET1A_HUMAN
NC score	0.007057 (rank : 55)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	690	Shared Neighborhood Hits	13
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PCLO_MOUSE
NC score	0.006976 (rank : 56)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	2275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UBP43_HUMAN
NC score	0.006953 (rank : 57)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

MNT_MOUSE
NC score	0.006828 (rank : 58)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	432	Shared Neighborhood Hits	13
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

ES8L3_HUMAN
NC score	0.006737 (rank : 59)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FGD1_MOUSE
NC score	0.006521 (rank : 60)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

DDEF2_HUMAN
NC score	0.006378 (rank : 61)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	599	Shared Neighborhood Hits	15
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TARA_MOUSE
NC score	0.006366 (rank : 62)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

COHA1_MOUSE
NC score	0.004713 (rank : 63)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	414	Shared Neighborhood Hits	11
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CENG1_HUMAN
NC score	0.003986 (rank : 64)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	544	Shared Neighborhood Hits	6
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

PTN23_MOUSE
NC score	0.003959 (rank : 65)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	726	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CNTP1_HUMAN
NC score	0.003601 (rank : 66)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

ZYX_MOUSE
NC score	0.003446 (rank : 67)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	347	Shared Neighborhood Hits	10
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

LDB3_MOUSE
NC score	0.002653 (rank : 68)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	510	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

HXA3_MOUSE
NC score	0.002615 (rank : 69)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	558	Shared Neighborhood Hits	10
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

ADA12_HUMAN
NC score	0.001814 (rank : 70)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	224	Shared Neighborhood Hits	2
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

FREA_HUMAN
NC score	0.001547 (rank : 71)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

ASPP2_HUMAN
NC score	0.001375 (rank : 72)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	1156	Shared Neighborhood Hits	16
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

M4K1_HUMAN
NC score	-0.000135 (rank : 73)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	884	Shared Neighborhood Hits	3
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

MTLR_HUMAN
NC score	-0.000926 (rank : 74)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	796	Shared Neighborhood Hits	2
SwissProt Accessions	O43193	Gene names	MLNR, GPR38, MTLR, MTLR1
Domain Architecture
Description	Motilin receptor (G-protein coupled receptor 38).

DYR1B_MOUSE
NC score	-0.001121 (rank : 75)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	799	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).