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Network neighborhood for query Sequence : MMP21_HUMAN

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MMP21_HUMAN
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MMP21_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP21_MOUSE
θ value	0 (rank : 2)	NC score	0.996674 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP17_MOUSE
θ value	1.73182e-43 (rank : 3)	NC score	0.939972 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP19_MOUSE
θ value	3.05695e-40 (rank : 4)	NC score	0.942917 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHI0, Q8C360	Gene names	Mmp19, Rasi
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI).

MMP17_HUMAN
θ value	5.21438e-40 (rank : 5)	NC score	0.939244 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ULZ9, Q14850	Gene names	MMP17, MT4MMP
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP19_HUMAN
θ value	4.88048e-38 (rank : 6)	NC score	0.943364 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q99542, O15278, O95606, Q99580	Gene names	MMP19, MMP18, RASI
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI) (MMP-18).

MMP10_MOUSE
θ value	3.4976e-36 (rank : 7)	NC score	0.929231 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP24_MOUSE
θ value	7.79185e-36 (rank : 8)	NC score	0.927870 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP3_HUMAN
θ value	1.73584e-35 (rank : 9)	NC score	0.927004 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	50	Shared Neighborhood Hits	48
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP24_HUMAN
θ value	3.86705e-35 (rank : 10)	NC score	0.925001 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP10_HUMAN
θ value	5.0505e-35 (rank : 11)	NC score	0.927066 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	50	Shared Neighborhood Hits	46
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP3_MOUSE
θ value	6.59618e-35 (rank : 12)	NC score	0.927313 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	53	Shared Neighborhood Hits	48
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP12_HUMAN
θ value	4.27553e-34 (rank : 13)	NC score	0.929813 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	48
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP8_MOUSE
θ value	2.12192e-33 (rank : 14)	NC score	0.926527 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	48
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

MMP1A_MOUSE
θ value	3.61944e-33 (rank : 15)	NC score	0.926101 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP1B_MOUSE
θ value	3.06405e-32 (rank : 16)	NC score	0.925748 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP14_MOUSE
θ value	4.00176e-32 (rank : 17)	NC score	0.925095 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	48
SwissProt Accessions	P53690, O08645, O35369	Gene names	Mmp14, Mtmmp
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP-X1) (MT-MMP).

MMP15_MOUSE
θ value	8.91499e-32 (rank : 18)	NC score	0.919727 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP14_HUMAN
θ value	1.52067e-31 (rank : 19)	NC score	0.925035 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

MMP12_MOUSE
θ value	1.98606e-31 (rank : 20)	NC score	0.930811 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP28_HUMAN
θ value	4.42448e-31 (rank : 21)	NC score	0.939606 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP11_MOUSE
θ value	7.54701e-31 (rank : 22)	NC score	0.929119 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP25_HUMAN
θ value	7.54701e-31 (rank : 23)	NC score	0.933979 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPA2, Q9H3Q0	Gene names	MMP25, MT6MMP
Domain Architecture
Description	Matrix metalloproteinase-25 precursor (EC 3.4.24.-) (MMP-25) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (Leukolysin).

MMP16_MOUSE
θ value	2.19584e-30 (rank : 24)	NC score	0.919491 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP16_HUMAN
θ value	3.74554e-30 (rank : 25)	NC score	0.919516 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP8_HUMAN
θ value	3.74554e-30 (rank : 26)	NC score	0.923126 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	54	Shared Neighborhood Hits	48
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP1_HUMAN
θ value	1.08979e-29 (rank : 27)	NC score	0.922425 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	46
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP13_HUMAN
θ value	3.17079e-29 (rank : 28)	NC score	0.923919 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP20_HUMAN
θ value	3.17079e-29 (rank : 29)	NC score	0.922359 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP13_MOUSE
θ value	5.40856e-29 (rank : 30)	NC score	0.923021 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP11_HUMAN
θ value	1.73987e-27 (rank : 31)	NC score	0.928368 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP20_MOUSE
θ value	8.63488e-27 (rank : 32)	NC score	0.920157 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP7_HUMAN
θ value	1.16704e-23 (rank : 33)	NC score	0.916929 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_MOUSE
θ value	7.0802e-21 (rank : 34)	NC score	0.913495 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP15_HUMAN
θ value	1.5773e-20 (rank : 35)	NC score	0.910994 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MMP2_MOUSE
θ value	4.58923e-20 (rank : 36)	NC score	0.842786 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP2_HUMAN
θ value	1.74391e-19 (rank : 37)	NC score	0.842182 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP26_HUMAN
θ value	5.60996e-18 (rank : 38)	NC score	0.915133 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP9_HUMAN
θ value	6.00763e-12 (rank : 39)	NC score	0.794929 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
θ value	1.63604e-09 (rank : 40)	NC score	0.784377 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

VTNC_MOUSE
θ value	4.92598e-06 (rank : 41)	NC score	0.690146 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

VTNC_HUMAN
θ value	1.87187e-05 (rank : 42)	NC score	0.662719 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	43
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

PRG4_MOUSE
θ value	0.00035302 (rank : 43)	NC score	0.358809 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

HEMO_MOUSE
θ value	0.000461057 (rank : 44)	NC score	0.578204 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q91X72, P97824, Q8WUP0	Gene names	Hpx, Hpxn
Domain Architecture
Description	Hemopexin precursor.

HEMO_HUMAN
θ value	0.000786445 (rank : 45)	NC score	0.643644 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

PRG4_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.301109 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	764	Shared Neighborhood Hits	49
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

KCNQ1_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.009736 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

HA15_MOUSE
θ value	0.813845 (rank : 48)	NC score	0.011825 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	P06339	Gene names	H2-T23
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-37 alpha chain precursor.

HA17_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.011913 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	P14429	Gene names	H2-Q7
Domain Architecture
Description	H-2 class I histocompatibility antigen, Q7 alpha chain precursor (QA-2 antigen).

HA18_MOUSE
θ value	0.813845 (rank : 50)	NC score	0.012034 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P14430	Gene names	H2-Q8
Domain Architecture
Description	H-2 class I histocompatibility antigen, Q8 alpha chain precursor.

HA13_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.011929 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	P14426	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-K alpha chain precursor (H- 2D(K)).

HA14_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.011802 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	P14427	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-P alpha chain precursor (H- 2D(P)).

I11RA_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.012525 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

SAPS1_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.010141 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	704	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

DUET_HUMAN
θ value	1.81305 (rank : 55)	NC score	-0.003330 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	1220	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

SPEG_MOUSE
θ value	1.81305 (rank : 56)	NC score	-0.002658 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	1959	Shared Neighborhood Hits	15
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ATS13_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.054240 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	238	Shared Neighborhood Hits	37
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

A1BG_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.010346 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

ATS13_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.041411 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

HA1D_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.011207 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P01902	Gene names	H2-K1, H2-K
Domain Architecture
Description	H-2 class I histocompatibility antigen, K-D alpha chain precursor (H- 2K(D)).

HA11_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.011044 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	P01899	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-B alpha chain precursor (H- 2D(B)).

HA1L_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.010881 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	11
SwissProt Accessions	P01897, Q31195, Q31196, Q31197	Gene names	H2-L
Domain Architecture
Description	H-2 class I histocompatibility antigen, L-D alpha chain precursor.

PKHA4_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.008380 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	283	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

TAF6L_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.010772 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

ATS2_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.016428 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

HA1T_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.010536 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	215	Shared Neighborhood Hits	11
SwissProt Accessions	P14432, Q31194, Q31203	Gene names	H2-T3
Domain Architecture
Description	H-2 class I histocompatibility antigen, TLA(B) alpha chain precursor (MHC thymus leukemia antigen).

MDC1_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.010763 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	998	Shared Neighborhood Hits	9
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PAPPA_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.010615 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

AMZ2_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.012857 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q400C8, Q8BVM5, Q8K3B9, Q9D121	Gene names	Amz2
Domain Architecture	No domain graphic available
Description	Archaemetzincin-2 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 2).

ATS2_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.015859 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

BSN_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.003146 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	2057	Shared Neighborhood Hits	14
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

HA12_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.010588 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P01900	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-D alpha chain precursor (H- 2D(D)).

MYO9B_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.001725 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	641	Shared Neighborhood Hits	8
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PAPPA_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.009861 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SSH1_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.003259 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

GA2L2_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.007989 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	395	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SEL1L_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.060043 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.058426 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

Hits sorted by NC score

MMP21_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP21_MOUSE
NC score	0.996674 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP19_HUMAN
NC score	0.943364 (rank : 3)	θ value	4.88048e-38 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q99542, O15278, O95606, Q99580	Gene names	MMP19, MMP18, RASI
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI) (MMP-18).

MMP19_MOUSE
NC score	0.942917 (rank : 4)	θ value	3.05695e-40 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHI0, Q8C360	Gene names	Mmp19, Rasi
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI).

MMP17_MOUSE
NC score	0.939972 (rank : 5)	θ value	1.73182e-43 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP28_HUMAN
NC score	0.939606 (rank : 6)	θ value	4.42448e-31 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP17_HUMAN
NC score	0.939244 (rank : 7)	θ value	5.21438e-40 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ULZ9, Q14850	Gene names	MMP17, MT4MMP
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP25_HUMAN
NC score	0.933979 (rank : 8)	θ value	7.54701e-31 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPA2, Q9H3Q0	Gene names	MMP25, MT6MMP
Domain Architecture
Description	Matrix metalloproteinase-25 precursor (EC 3.4.24.-) (MMP-25) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (Leukolysin).

MMP12_MOUSE
NC score	0.930811 (rank : 9)	θ value	1.98606e-31 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP12_HUMAN
NC score	0.929813 (rank : 10)	θ value	4.27553e-34 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	48
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP10_MOUSE
NC score	0.929231 (rank : 11)	θ value	3.4976e-36 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP11_MOUSE
NC score	0.929119 (rank : 12)	θ value	7.54701e-31 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_HUMAN
NC score	0.928368 (rank : 13)	θ value	1.73987e-27 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP24_MOUSE
NC score	0.927870 (rank : 14)	θ value	7.79185e-36 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP3_MOUSE
NC score	0.927313 (rank : 15)	θ value	6.59618e-35 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	53	Shared Neighborhood Hits	48
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP10_HUMAN
NC score	0.927066 (rank : 16)	θ value	5.0505e-35 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	50	Shared Neighborhood Hits	46
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP3_HUMAN
NC score	0.927004 (rank : 17)	θ value	1.73584e-35 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	50	Shared Neighborhood Hits	48
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP8_MOUSE
NC score	0.926527 (rank : 18)	θ value	2.12192e-33 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	48
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

MMP1A_MOUSE
NC score	0.926101 (rank : 19)	θ value	3.61944e-33 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP1B_MOUSE
NC score	0.925748 (rank : 20)	θ value	3.06405e-32 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP14_MOUSE
NC score	0.925095 (rank : 21)	θ value	4.00176e-32 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	48
SwissProt Accessions	P53690, O08645, O35369	Gene names	Mmp14, Mtmmp
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP-X1) (MT-MMP).

MMP14_HUMAN
NC score	0.925035 (rank : 22)	θ value	1.52067e-31 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

MMP24_HUMAN
NC score	0.925001 (rank : 23)	θ value	3.86705e-35 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP13_HUMAN
NC score	0.923919 (rank : 24)	θ value	3.17079e-29 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP8_HUMAN
NC score	0.923126 (rank : 25)	θ value	3.74554e-30 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	54	Shared Neighborhood Hits	48
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP13_MOUSE
NC score	0.923021 (rank : 26)	θ value	5.40856e-29 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP1_HUMAN
NC score	0.922425 (rank : 27)	θ value	1.08979e-29 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	46
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP20_HUMAN
NC score	0.922359 (rank : 28)	θ value	3.17079e-29 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP20_MOUSE
NC score	0.920157 (rank : 29)	θ value	8.63488e-27 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP15_MOUSE
NC score	0.919727 (rank : 30)	θ value	8.91499e-32 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP16_HUMAN
NC score	0.919516 (rank : 31)	θ value	3.74554e-30 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP16_MOUSE
NC score	0.919491 (rank : 32)	θ value	2.19584e-30 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP7_HUMAN
NC score	0.916929 (rank : 33)	θ value	1.16704e-23 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP26_HUMAN
NC score	0.915133 (rank : 34)	θ value	5.60996e-18 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP7_MOUSE
NC score	0.913495 (rank : 35)	θ value	7.0802e-21 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP15_HUMAN
NC score	0.910994 (rank : 36)	θ value	1.5773e-20 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MMP2_MOUSE
NC score	0.842786 (rank : 37)	θ value	4.58923e-20 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP2_HUMAN
NC score	0.842182 (rank : 38)	θ value	1.74391e-19 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP9_HUMAN
NC score	0.794929 (rank : 39)	θ value	6.00763e-12 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
NC score	0.784377 (rank : 40)	θ value	1.63604e-09 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

VTNC_MOUSE
NC score	0.690146 (rank : 41)	θ value	4.92598e-06 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

VTNC_HUMAN
NC score	0.662719 (rank : 42)	θ value	1.87187e-05 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	43
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

HEMO_HUMAN
NC score	0.643644 (rank : 43)	θ value	0.000786445 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

HEMO_MOUSE
NC score	0.578204 (rank : 44)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q91X72, P97824, Q8WUP0	Gene names	Hpx, Hpxn
Domain Architecture
Description	Hemopexin precursor.

PRG4_MOUSE
NC score	0.358809 (rank : 45)	θ value	0.00035302 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.301109 (rank : 46)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	764	Shared Neighborhood Hits	49
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SEL1L_HUMAN
NC score	0.060043 (rank : 47)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
NC score	0.058426 (rank : 48)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

ATS13_HUMAN
NC score	0.054240 (rank : 49)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	238	Shared Neighborhood Hits	37
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.041411 (rank : 50)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS2_HUMAN
NC score	0.016428 (rank : 51)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.015859 (rank : 52)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

AMZ2_MOUSE
NC score	0.012857 (rank : 53)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q400C8, Q8BVM5, Q8K3B9, Q9D121	Gene names	Amz2
Domain Architecture	No domain graphic available
Description	Archaemetzincin-2 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 2).

I11RA_HUMAN
NC score	0.012525 (rank : 54)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

HA18_MOUSE
NC score	0.012034 (rank : 55)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P14430	Gene names	H2-Q8
Domain Architecture
Description	H-2 class I histocompatibility antigen, Q8 alpha chain precursor.

HA13_MOUSE
NC score	0.011929 (rank : 56)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	P14426	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-K alpha chain precursor (H- 2D(K)).

HA17_MOUSE
NC score	0.011913 (rank : 57)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	P14429	Gene names	H2-Q7
Domain Architecture
Description	H-2 class I histocompatibility antigen, Q7 alpha chain precursor (QA-2 antigen).

HA15_MOUSE
NC score	0.011825 (rank : 58)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	P06339	Gene names	H2-T23
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-37 alpha chain precursor.

HA14_MOUSE
NC score	0.011802 (rank : 59)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	P14427	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-P alpha chain precursor (H- 2D(P)).

HA1D_MOUSE
NC score	0.011207 (rank : 60)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P01902	Gene names	H2-K1, H2-K
Domain Architecture
Description	H-2 class I histocompatibility antigen, K-D alpha chain precursor (H- 2K(D)).

HA11_MOUSE
NC score	0.011044 (rank : 61)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	P01899	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-B alpha chain precursor (H- 2D(B)).

HA1L_MOUSE
NC score	0.010881 (rank : 62)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	11
SwissProt Accessions	P01897, Q31195, Q31196, Q31197	Gene names	H2-L
Domain Architecture
Description	H-2 class I histocompatibility antigen, L-D alpha chain precursor.

TAF6L_MOUSE
NC score	0.010772 (rank : 63)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

MDC1_MOUSE
NC score	0.010763 (rank : 64)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	998	Shared Neighborhood Hits	9
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PAPPA_HUMAN
NC score	0.010615 (rank : 65)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

HA12_MOUSE
NC score	0.010588 (rank : 66)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P01900	Gene names	H2-D1
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-D alpha chain precursor (H- 2D(D)).

HA1T_MOUSE
NC score	0.010536 (rank : 67)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	215	Shared Neighborhood Hits	11
SwissProt Accessions	P14432, Q31194, Q31203	Gene names	H2-T3
Domain Architecture
Description	H-2 class I histocompatibility antigen, TLA(B) alpha chain precursor (MHC thymus leukemia antigen).

A1BG_HUMAN
NC score	0.010346 (rank : 68)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

SAPS1_HUMAN
NC score	0.010141 (rank : 69)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	704	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

PAPPA_MOUSE
NC score	0.009861 (rank : 70)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

KCNQ1_MOUSE
NC score	0.009736 (rank : 71)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PKHA4_HUMAN
NC score	0.008380 (rank : 72)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	283	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

GA2L2_MOUSE
NC score	0.007989 (rank : 73)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	395	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SSH1_MOUSE
NC score	0.003259 (rank : 74)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

BSN_MOUSE
NC score	0.003146 (rank : 75)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	2057	Shared Neighborhood Hits	14
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MYO9B_HUMAN
NC score	0.001725 (rank : 76)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	641	Shared Neighborhood Hits	8
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SPEG_MOUSE
NC score	-0.002658 (rank : 77)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	1959	Shared Neighborhood Hits	15
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DUET_HUMAN
NC score	-0.003330 (rank : 78)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	1220	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).