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Network neighborhood for query Sequence : MMP9_HUMAN

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MMP9_HUMAN
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MMP9_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
θ value	0 (rank : 2)	NC score	0.990348 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	151	Shared Neighborhood Hits	91
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP2_HUMAN
θ value	1.12453e-151 (rank : 3)	NC score	0.981019 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP2_MOUSE
θ value	1.62381e-150 (rank : 4)	NC score	0.980949 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP3_HUMAN
θ value	2.85459e-46 (rank : 5)	NC score	0.873476 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP10_HUMAN
θ value	4.122e-45 (rank : 6)	NC score	0.873272 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP13_HUMAN
θ value	9.18288e-45 (rank : 7)	NC score	0.875509 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP10_MOUSE
θ value	1.56636e-44 (rank : 8)	NC score	0.873860 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	45
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP13_MOUSE
θ value	5.95217e-44 (rank : 9)	NC score	0.874472 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP1_HUMAN
θ value	2.95404e-43 (rank : 10)	NC score	0.872165 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP3_MOUSE
θ value	6.58091e-43 (rank : 11)	NC score	0.872856 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP8_MOUSE
θ value	9.83387e-39 (rank : 12)	NC score	0.869386 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

MMP12_HUMAN
θ value	5.39604e-37 (rank : 13)	NC score	0.868320 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP1A_MOUSE
θ value	7.04741e-37 (rank : 14)	NC score	0.868866 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP20_HUMAN
θ value	9.20422e-37 (rank : 15)	NC score	0.868461 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP11_MOUSE
θ value	1.20211e-36 (rank : 16)	NC score	0.865862 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	46
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP12_MOUSE
θ value	3.4976e-36 (rank : 17)	NC score	0.869912 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP11_HUMAN
θ value	1.32909e-35 (rank : 18)	NC score	0.865027 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP20_MOUSE
θ value	6.59618e-35 (rank : 19)	NC score	0.868196 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP7_MOUSE
θ value	8.61488e-35 (rank : 20)	NC score	0.877205 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP8_HUMAN
θ value	9.52487e-34 (rank : 21)	NC score	0.867041 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	54	Shared Neighborhood Hits	47
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP7_HUMAN
θ value	1.6247e-33 (rank : 22)	NC score	0.877150 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

FINC_HUMAN
θ value	2.12192e-33 (rank : 23)	NC score	0.257159 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	302	Shared Neighborhood Hits	21
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	6.17384e-33 (rank : 24)	NC score	0.256450 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MMP1B_MOUSE
θ value	1.37539e-32 (rank : 25)	NC score	0.865947 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP14_HUMAN
θ value	1.52067e-31 (rank : 26)	NC score	0.848879 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

MMP14_MOUSE
θ value	2.59387e-31 (rank : 27)	NC score	0.848219 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P53690, O08645, O35369	Gene names	Mmp14, Mtmmp
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP-X1) (MT-MMP).

MMP24_MOUSE
θ value	3.74554e-30 (rank : 28)	NC score	0.849533 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP24_HUMAN
θ value	8.3442e-30 (rank : 29)	NC score	0.847625 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	66	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP16_HUMAN
θ value	1.08979e-29 (rank : 30)	NC score	0.845538 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP16_MOUSE
θ value	2.42779e-29 (rank : 31)	NC score	0.845286 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP15_HUMAN
θ value	9.2256e-29 (rank : 32)	NC score	0.843718 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MMP17_MOUSE
θ value	2.96777e-27 (rank : 33)	NC score	0.850066 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP15_MOUSE
θ value	3.87602e-27 (rank : 34)	NC score	0.839129 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	57
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP17_HUMAN
θ value	5.59698e-26 (rank : 35)	NC score	0.850148 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULZ9, Q14850	Gene names	MMP17, MT4MMP
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP26_HUMAN
θ value	1.80048e-24 (rank : 36)	NC score	0.867968 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP19_MOUSE
θ value	4.43474e-23 (rank : 37)	NC score	0.843510 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JHI0, Q8C360	Gene names	Mmp19, Rasi
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI).

MMP25_HUMAN
θ value	1.09232e-21 (rank : 38)	NC score	0.850169 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPA2, Q9H3Q0	Gene names	MMP25, MT6MMP
Domain Architecture
Description	Matrix metalloproteinase-25 precursor (EC 3.4.24.-) (MMP-25) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (Leukolysin).

MMP28_HUMAN
θ value	4.15078e-21 (rank : 39)	NC score	0.840574 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP19_HUMAN
θ value	7.32683e-18 (rank : 40)	NC score	0.838335 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	Q99542, O15278, O95606, Q99580	Gene names	MMP19, MMP18, RASI
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI) (MMP-18).

MRC1_HUMAN
θ value	6.85773e-16 (rank : 41)	NC score	0.270799 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC1_MOUSE
θ value	1.52774e-15 (rank : 42)	NC score	0.276342 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

SEL1L_HUMAN
θ value	5.8054e-15 (rank : 43)	NC score	0.395309 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
θ value	5.8054e-15 (rank : 44)	NC score	0.390595 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

MRC2_HUMAN
θ value	3.76295e-14 (rank : 45)	NC score	0.261650 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

MRC2_MOUSE
θ value	1.09485e-13 (rank : 46)	NC score	0.262005 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	159	Shared Neighborhood Hits	20
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MMP21_HUMAN
θ value	6.00763e-12 (rank : 47)	NC score	0.794929 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

LY75_HUMAN
θ value	2.52405e-10 (rank : 48)	NC score	0.250148 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

MPRI_MOUSE
θ value	4.30538e-10 (rank : 49)	NC score	0.290011 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

HGFA_HUMAN
θ value	9.59137e-10 (rank : 50)	NC score	0.093730 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	436	Shared Neighborhood Hits	24
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MPRI_HUMAN
θ value	2.13673e-09 (rank : 51)	NC score	0.284082 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

FA12_HUMAN
θ value	3.64472e-09 (rank : 52)	NC score	0.095959 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

MMP21_MOUSE
θ value	3.64472e-09 (rank : 53)	NC score	0.788658 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

LY75_MOUSE
θ value	6.21693e-09 (rank : 54)	NC score	0.246667 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	155	Shared Neighborhood Hits	20
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

HGFA_MOUSE
θ value	1.38499e-08 (rank : 55)	NC score	0.092777 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

VTNC_MOUSE
θ value	1.29631e-06 (rank : 56)	NC score	0.613358 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	42
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

HEMO_MOUSE
θ value	3.19293e-05 (rank : 57)	NC score	0.536379 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	Q91X72, P97824, Q8WUP0	Gene names	Hpx, Hpxn
Domain Architecture
Description	Hemopexin precursor.

HEMO_HUMAN
θ value	5.44631e-05 (rank : 58)	NC score	0.579795 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

VTNC_HUMAN
θ value	0.000602161 (rank : 59)	NC score	0.584703 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

MUC1_HUMAN
θ value	0.000786445 (rank : 60)	NC score	0.029773 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	975	Shared Neighborhood Hits	34
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PRG4_MOUSE
θ value	0.000786445 (rank : 61)	NC score	0.323533 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	624	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

OGFR_HUMAN
θ value	0.00665767 (rank : 62)	NC score	0.033448 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	1582	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

GP152_HUMAN
θ value	0.0148317 (rank : 63)	NC score	0.034044 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	636	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

SON_HUMAN
θ value	0.0148317 (rank : 64)	NC score	0.024030 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	1568	Shared Neighborhood Hits	40
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CP003_HUMAN
θ value	0.0252991 (rank : 65)	NC score	0.092605 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CEL_HUMAN
θ value	0.0563607 (rank : 66)	NC score	0.022417 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FGF23_MOUSE
θ value	0.0563607 (rank : 67)	NC score	0.024494 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPC2	Gene names	Fgf23
Domain Architecture
Description	Fibroblast growth factor 23 precursor (FGF-23).

SOX30_HUMAN
θ value	0.125558 (rank : 68)	NC score	0.016141 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	305	Shared Neighborhood Hits	13
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

NRX2A_HUMAN
θ value	0.163984 (rank : 69)	NC score	0.025937 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	614	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.034400 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	481	Shared Neighborhood Hits	22
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

TSNA1_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.034967 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

ATS13_MOUSE
θ value	0.279714 (rank : 72)	NC score	0.049036 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

FBX46_MOUSE
θ value	0.365318 (rank : 73)	NC score	0.019945 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

MAGE1_HUMAN
θ value	0.365318 (rank : 74)	NC score	0.019986 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	1389	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TGON2_MOUSE
θ value	0.47712 (rank : 75)	NC score	0.038278 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

3BHS6_MOUSE
θ value	0.813845 (rank : 76)	NC score	0.017034 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	O35469	Gene names	Hsd3b6
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type VI (3Beta-HSD VI) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

ATS13_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.058913 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CSKI1_MOUSE
θ value	0.813845 (rank : 78)	NC score	0.009585 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	1031	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MTR1L_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.000013 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	1180	Shared Neighborhood Hits	16
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

LPP_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.011076 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	775	Shared Neighborhood Hits	28
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MDC1_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.019454 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	1446	Shared Neighborhood Hits	32
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NACAM_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.023117 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	1866	Shared Neighborhood Hits	44
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GP152_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.014005 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	607	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

JIP3_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.016548 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	1039	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MUCDL_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.020753 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	777	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

BCL7C_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.029424 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CSKI1_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.012226 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	997	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DEDD_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.022354 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

BAZ2A_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.010292 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	780	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

FGD1_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.005176 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	387	Shared Neighborhood Hits	16
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SSBP4_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.013306 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TGON1_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.024825 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

CN032_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.033237 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

NFAC1_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.009486 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

RECQ5_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.006495 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	390	Shared Neighborhood Hits	13
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RP3A_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.010886 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	510	Shared Neighborhood Hits	22
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SC24C_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.013723 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	662	Shared Neighborhood Hits	23
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SEM6C_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.004806 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

CSMD1_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.000873 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LSD1_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.008905 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

RT35_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.010157 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

AAK1_MOUSE
θ value	6.88961 (rank : 102)	NC score	-0.003580 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	1051	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ATS2_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.018537 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	179	Shared Neighborhood Hits	24
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.018279 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	179	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.016159 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

BSN_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.013990 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	1537	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DEDD_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.011952 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1L3, Q7TQH8, Q9R227	Gene names	Dedd
Domain Architecture
Description	Death effector domain-containing protein (DEDPro1).

EGR2_HUMAN
θ value	6.88961 (rank : 108)	NC score	-0.006086 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	728	Shared Neighborhood Hits	3
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

FOXO4_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.007870 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

INP5E_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.013783 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

NKX31_MOUSE
θ value	6.88961 (rank : 111)	NC score	-0.002051 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	379	Shared Neighborhood Hits	3
SwissProt Accessions	P97436, O09087	Gene names	Nkx3-1, Nkx-3.1, Nkx3a
Domain Architecture
Description	Homeobox protein Nkx-3.1.

TBX18_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.001847 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

XKR7_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.004118 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

ADA15_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.007352 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ATS14_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.013023 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	382	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

CAC1G_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.000740 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	587	Shared Neighborhood Hits	15
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

ESAM_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.001586 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

FOXO4_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.010141 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

K2027_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.007324 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MLL2_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.008885 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	1788	Shared Neighborhood Hits	47
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PGCA_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.041738 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

RP1L1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.006495 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	1072	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RUNX2_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.003993 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SPR1A_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.016960 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SYNJ1_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.013557 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CD302_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.076323 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.075396 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

CHODL_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.060266 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.060181 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

EMBP_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.053566 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

PRG3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.054916 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

PRG3_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.052523 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

PRG4_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.264892 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	764	Shared Neighborhood Hits	70
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

Hits sorted by NC score

MMP9_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
NC score	0.990348 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	151	Shared Neighborhood Hits	91
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP2_HUMAN
NC score	0.981019 (rank : 3)	θ value	1.12453e-151 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP2_MOUSE
NC score	0.980949 (rank : 4)	θ value	1.62381e-150 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP7_MOUSE
NC score	0.877205 (rank : 5)	θ value	8.61488e-35 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_HUMAN
NC score	0.877150 (rank : 6)	θ value	1.6247e-33 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP13_HUMAN
NC score	0.875509 (rank : 7)	θ value	9.18288e-45 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP13_MOUSE
NC score	0.874472 (rank : 8)	θ value	5.95217e-44 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP10_MOUSE
NC score	0.873860 (rank : 9)	θ value	1.56636e-44 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	45
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP3_HUMAN
NC score	0.873476 (rank : 10)	θ value	2.85459e-46 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP10_HUMAN
NC score	0.873272 (rank : 11)	θ value	4.122e-45 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP3_MOUSE
NC score	0.872856 (rank : 12)	θ value	6.58091e-43 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP1_HUMAN
NC score	0.872165 (rank : 13)	θ value	2.95404e-43 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP12_MOUSE
NC score	0.869912 (rank : 14)	θ value	3.4976e-36 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP8_MOUSE
NC score	0.869386 (rank : 15)	θ value	9.83387e-39 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

MMP1A_MOUSE
NC score	0.868866 (rank : 16)	θ value	7.04741e-37 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP20_HUMAN
NC score	0.868461 (rank : 17)	θ value	9.20422e-37 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP12_HUMAN
NC score	0.868320 (rank : 18)	θ value	5.39604e-37 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP20_MOUSE
NC score	0.868196 (rank : 19)	θ value	6.59618e-35 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP26_HUMAN
NC score	0.867968 (rank : 20)	θ value	1.80048e-24 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP8_HUMAN
NC score	0.867041 (rank : 21)	θ value	9.52487e-34 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	54	Shared Neighborhood Hits	47
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP1B_MOUSE
NC score	0.865947 (rank : 22)	θ value	1.37539e-32 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP11_MOUSE
NC score	0.865862 (rank : 23)	θ value	1.20211e-36 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	46
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_HUMAN
NC score	0.865027 (rank : 24)	θ value	1.32909e-35 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP25_HUMAN
NC score	0.850169 (rank : 25)	θ value	1.09232e-21 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPA2, Q9H3Q0	Gene names	MMP25, MT6MMP
Domain Architecture
Description	Matrix metalloproteinase-25 precursor (EC 3.4.24.-) (MMP-25) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (Leukolysin).

MMP17_HUMAN
NC score	0.850148 (rank : 26)	θ value	5.59698e-26 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULZ9, Q14850	Gene names	MMP17, MT4MMP
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP17_MOUSE
NC score	0.850066 (rank : 27)	θ value	2.96777e-27 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP24_MOUSE
NC score	0.849533 (rank : 28)	θ value	3.74554e-30 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP14_HUMAN
NC score	0.848879 (rank : 29)	θ value	1.52067e-31 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

MMP14_MOUSE
NC score	0.848219 (rank : 30)	θ value	2.59387e-31 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P53690, O08645, O35369	Gene names	Mmp14, Mtmmp
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP-X1) (MT-MMP).

MMP24_HUMAN
NC score	0.847625 (rank : 31)	θ value	8.3442e-30 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	66	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP16_HUMAN
NC score	0.845538 (rank : 32)	θ value	1.08979e-29 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP16_MOUSE
NC score	0.845286 (rank : 33)	θ value	2.42779e-29 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP15_HUMAN
NC score	0.843718 (rank : 34)	θ value	9.2256e-29 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MMP19_MOUSE
NC score	0.843510 (rank : 35)	θ value	4.43474e-23 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JHI0, Q8C360	Gene names	Mmp19, Rasi
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI).

MMP28_HUMAN
NC score	0.840574 (rank : 36)	θ value	4.15078e-21 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP15_MOUSE
NC score	0.839129 (rank : 37)	θ value	3.87602e-27 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	57
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP19_HUMAN
NC score	0.838335 (rank : 38)	θ value	7.32683e-18 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	Q99542, O15278, O95606, Q99580	Gene names	MMP19, MMP18, RASI
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI) (MMP-18).

MMP21_HUMAN
NC score	0.794929 (rank : 39)	θ value	6.00763e-12 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP21_MOUSE
NC score	0.788658 (rank : 40)	θ value	3.64472e-09 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

VTNC_MOUSE
NC score	0.613358 (rank : 41)	θ value	1.29631e-06 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	42
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

VTNC_HUMAN
NC score	0.584703 (rank : 42)	θ value	0.000602161 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

HEMO_HUMAN
NC score	0.579795 (rank : 43)	θ value	5.44631e-05 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

HEMO_MOUSE
NC score	0.536379 (rank : 44)	θ value	3.19293e-05 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	Q91X72, P97824, Q8WUP0	Gene names	Hpx, Hpxn
Domain Architecture
Description	Hemopexin precursor.

SEL1L_HUMAN
NC score	0.395309 (rank : 45)	θ value	5.8054e-15 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
NC score	0.390595 (rank : 46)	θ value	5.8054e-15 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

PRG4_MOUSE
NC score	0.323533 (rank : 47)	θ value	0.000786445 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	624	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MPRI_MOUSE
NC score	0.290011 (rank : 48)	θ value	4.30538e-10 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

MPRI_HUMAN
NC score	0.284082 (rank : 49)	θ value	2.13673e-09 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MRC1_MOUSE
NC score	0.276342 (rank : 50)	θ value	1.52774e-15 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC1_HUMAN
NC score	0.270799 (rank : 51)	θ value	6.85773e-16 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

PRG4_HUMAN
NC score	0.264892 (rank : 52)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	764	Shared Neighborhood Hits	70
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MRC2_MOUSE
NC score	0.262005 (rank : 53)	θ value	1.09485e-13 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	159	Shared Neighborhood Hits	20
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MRC2_HUMAN
NC score	0.261650 (rank : 54)	θ value	3.76295e-14 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

FINC_HUMAN
NC score	0.257159 (rank : 55)	θ value	2.12192e-33 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	302	Shared Neighborhood Hits	21
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.256450 (rank : 56)	θ value	6.17384e-33 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LY75_HUMAN
NC score	0.250148 (rank : 57)	θ value	2.52405e-10 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

LY75_MOUSE
NC score	0.246667 (rank : 58)	θ value	6.21693e-09 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	155	Shared Neighborhood Hits	20
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

FA12_HUMAN
NC score	0.095959 (rank : 59)	θ value	3.64472e-09 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

HGFA_HUMAN
NC score	0.093730 (rank : 60)	θ value	9.59137e-10 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	436	Shared Neighborhood Hits	24
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
NC score	0.092777 (rank : 61)	θ value	1.38499e-08 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CP003_HUMAN
NC score	0.092605 (rank : 62)	θ value	0.0252991 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CD302_HUMAN
NC score	0.076323 (rank : 63)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
NC score	0.075396 (rank : 64)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

CHODL_HUMAN
NC score	0.060266 (rank : 65)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_MOUSE
NC score	0.060181 (rank : 66)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

ATS13_HUMAN
NC score	0.058913 (rank : 67)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

PRG3_HUMAN
NC score	0.054916 (rank : 68)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

EMBP_MOUSE
NC score	0.053566 (rank : 69)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

PRG3_MOUSE
NC score	0.052523 (rank : 70)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

ATS13_MOUSE
NC score	0.049036 (rank : 71)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

PGCA_HUMAN
NC score	0.041738 (rank : 72)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TGON2_MOUSE
NC score	0.038278 (rank : 73)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TSNA1_HUMAN
NC score	0.034967 (rank : 74)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

NRX2B_HUMAN
NC score	0.034400 (rank : 75)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	481	Shared Neighborhood Hits	22
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

GP152_HUMAN
NC score	0.034044 (rank : 76)	θ value	0.0148317 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	636	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

OGFR_HUMAN
NC score	0.033448 (rank : 77)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	1582	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CN032_MOUSE
NC score	0.033237 (rank : 78)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

MUC1_HUMAN
NC score	0.029773 (rank : 79)	θ value	0.000786445 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	975	Shared Neighborhood Hits	34
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BCL7C_MOUSE
NC score	0.029424 (rank : 80)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

NRX2A_HUMAN
NC score	0.025937 (rank : 81)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	614	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TGON1_MOUSE
NC score	0.024825 (rank : 82)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

FGF23_MOUSE
NC score	0.024494 (rank : 83)	θ value	0.0563607 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPC2	Gene names	Fgf23
Domain Architecture
Description	Fibroblast growth factor 23 precursor (FGF-23).

SON_HUMAN
NC score	0.024030 (rank : 84)	θ value	0.0148317 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	1568	Shared Neighborhood Hits	40
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NACAM_MOUSE
NC score	0.023117 (rank : 85)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	1866	Shared Neighborhood Hits	44
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CEL_HUMAN
NC score	0.022417 (rank : 86)	θ value	0.0563607 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DEDD_HUMAN
NC score	0.022354 (rank : 87)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

MUCDL_HUMAN
NC score	0.020753 (rank : 88)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	777	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MAGE1_HUMAN
NC score	0.019986 (rank : 89)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	1389	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FBX46_MOUSE
NC score	0.019945 (rank : 90)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

MDC1_HUMAN
NC score	0.019454 (rank : 91)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	1446	Shared Neighborhood Hits	32
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ATS2_HUMAN
NC score	0.018537 (rank : 92)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	179	Shared Neighborhood Hits	24
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.018279 (rank : 93)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	179	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

3BHS6_MOUSE
NC score	0.017034 (rank : 94)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	O35469	Gene names	Hsd3b6
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type VI (3Beta-HSD VI) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

SPR1A_MOUSE
NC score	0.016960 (rank : 95)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

JIP3_HUMAN
NC score	0.016548 (rank : 96)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	1039	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

ATS3_HUMAN
NC score	0.016159 (rank : 97)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

SOX30_HUMAN
NC score	0.016141 (rank : 98)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	305	Shared Neighborhood Hits	13
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

GP152_MOUSE
NC score	0.014005 (rank : 99)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	607	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

BSN_HUMAN
NC score	0.013990 (rank : 100)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	1537	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

INP5E_HUMAN
NC score	0.013783 (rank : 101)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

SC24C_HUMAN
NC score	0.013723 (rank : 102)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	662	Shared Neighborhood Hits	23
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SYNJ1_MOUSE
NC score	0.013557 (rank : 103)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SSBP4_HUMAN
NC score	0.013306 (rank : 104)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ATS14_HUMAN
NC score	0.013023 (rank : 105)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	382	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

CSKI1_HUMAN
NC score	0.012226 (rank : 106)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	997	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DEDD_MOUSE
NC score	0.011952 (rank : 107)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1L3, Q7TQH8, Q9R227	Gene names	Dedd
Domain Architecture
Description	Death effector domain-containing protein (DEDPro1).

LPP_HUMAN
NC score	0.011076 (rank : 108)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	775	Shared Neighborhood Hits	28
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

RP3A_MOUSE
NC score	0.010886 (rank : 109)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	510	Shared Neighborhood Hits	22
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

BAZ2A_HUMAN
NC score	0.010292 (rank : 110)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	780	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

RT35_MOUSE
NC score	0.010157 (rank : 111)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

FOXO4_HUMAN
NC score	0.010141 (rank : 112)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

CSKI1_MOUSE
NC score	0.009585 (rank : 113)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	1031	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NFAC1_HUMAN
NC score	0.009486 (rank : 114)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

LSD1_HUMAN
NC score	0.008905 (rank : 115)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MLL2_HUMAN
NC score	0.008885 (rank : 116)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	1788	Shared Neighborhood Hits	47
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FOXO4_MOUSE
NC score	0.007870 (rank : 117)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

ADA15_MOUSE
NC score	0.007352 (rank : 118)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

K2027_HUMAN
NC score	0.007324 (rank : 119)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

RECQ5_HUMAN
NC score	0.006495 (rank : 120)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	390	Shared Neighborhood Hits	13
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RP1L1_HUMAN
NC score	0.006495 (rank : 121)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	1072	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

FGD1_MOUSE
NC score	0.005176 (rank : 122)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	387	Shared Neighborhood Hits	16
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SEM6C_MOUSE
NC score	0.004806 (rank : 123)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

XKR7_MOUSE
NC score	0.004118 (rank : 124)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

RUNX2_MOUSE
NC score	0.003993 (rank : 125)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

TBX18_HUMAN
NC score	0.001847 (rank : 126)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

ESAM_HUMAN
NC score	0.001586 (rank : 127)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

CSMD1_HUMAN
NC score	0.000873 (rank : 128)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CAC1G_HUMAN
NC score	0.000740 (rank : 129)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	587	Shared Neighborhood Hits	15
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

MTR1L_HUMAN
NC score	0.000013 (rank : 130)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	1180	Shared Neighborhood Hits	16
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NKX31_MOUSE
NC score	-0.002051 (rank : 131)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	379	Shared Neighborhood Hits	3
SwissProt Accessions	P97436, O09087	Gene names	Nkx3-1, Nkx-3.1, Nkx3a
Domain Architecture
Description	Homeobox protein Nkx-3.1.

AAK1_MOUSE
NC score	-0.003580 (rank : 132)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	1051	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

EGR2_HUMAN
NC score	-0.006086 (rank : 133)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	728	Shared Neighborhood Hits	3
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).