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Network neighborhood for query Sequence : MMP11_HUMAN

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MMP11_HUMAN
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MMP11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_MOUSE
θ value	0 (rank : 2)	NC score	0.998750 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	48
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP24_MOUSE
θ value	1.31072e-83 (rank : 3)	NC score	0.981753 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP24_HUMAN
θ value	3.81361e-83 (rank : 4)	NC score	0.981000 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP14_MOUSE
θ value	7.44272e-79 (rank : 5)	NC score	0.980969 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P53690, O08645, O35369	Gene names	Mmp14, Mtmmp
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP-X1) (MT-MMP).

MMP14_HUMAN
θ value	9.7205e-79 (rank : 6)	NC score	0.981097 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

MMP16_MOUSE
θ value	4.82422e-78 (rank : 7)	NC score	0.978546 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP25_HUMAN
θ value	4.82422e-78 (rank : 8)	NC score	0.985368 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPA2, Q9H3Q0	Gene names	MMP25, MT6MMP
Domain Architecture
Description	Matrix metalloproteinase-25 precursor (EC 3.4.24.-) (MMP-25) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (Leukolysin).

MMP16_HUMAN
θ value	6.30065e-78 (rank : 9)	NC score	0.978581 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP17_MOUSE
θ value	2.64714e-76 (rank : 10)	NC score	0.983108 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP15_HUMAN
θ value	1.31376e-75 (rank : 11)	NC score	0.976813 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MMP17_HUMAN
θ value	1.60597e-73 (rank : 12)	NC score	0.983197 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULZ9, Q14850	Gene names	MMP17, MT4MMP
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP15_MOUSE
θ value	2.31901e-72 (rank : 13)	NC score	0.976448 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP3_MOUSE
θ value	7.71989e-68 (rank : 14)	NC score	0.973561 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP3_HUMAN
θ value	4.23606e-66 (rank : 15)	NC score	0.972562 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP10_MOUSE
θ value	1.6097e-65 (rank : 16)	NC score	0.973997 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	49
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP1_HUMAN
θ value	1.6097e-65 (rank : 17)	NC score	0.971521 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	46
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP10_HUMAN
θ value	1.50663e-63 (rank : 18)	NC score	0.972409 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	46
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP13_HUMAN
θ value	9.1404e-61 (rank : 19)	NC score	0.972777 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP8_MOUSE
θ value	1.31987e-59 (rank : 20)	NC score	0.973219 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

MMP8_HUMAN
θ value	3.84025e-59 (rank : 21)	NC score	0.972137 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	47
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP19_HUMAN
θ value	2.48917e-58 (rank : 22)	NC score	0.974235 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q99542, O15278, O95606, Q99580	Gene names	MMP19, MMP18, RASI
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI) (MMP-18).

MMP20_HUMAN
θ value	2.48917e-58 (rank : 23)	NC score	0.971564 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP13_MOUSE
θ value	4.24587e-58 (rank : 24)	NC score	0.971108 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP12_HUMAN
θ value	5.54529e-58 (rank : 25)	NC score	0.974012 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP20_MOUSE
θ value	2.7521e-57 (rank : 26)	NC score	0.971127 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP1A_MOUSE
θ value	1.15626e-55 (rank : 27)	NC score	0.969709 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP12_MOUSE
θ value	5.73848e-55 (rank : 28)	NC score	0.972551 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP19_MOUSE
θ value	3.71957e-54 (rank : 29)	NC score	0.973323 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHI0, Q8C360	Gene names	Mmp19, Rasi
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI).

MMP28_HUMAN
θ value	5.37103e-53 (rank : 30)	NC score	0.977685 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP1B_MOUSE
θ value	6.56568e-51 (rank : 31)	NC score	0.967449 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP2_MOUSE
θ value	8.59492e-43 (rank : 32)	NC score	0.900936 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP2_HUMAN
θ value	4.2656e-42 (rank : 33)	NC score	0.900465 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP26_HUMAN
θ value	4.88048e-38 (rank : 34)	NC score	0.961959 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP7_MOUSE
θ value	7.79185e-36 (rank : 35)	NC score	0.958962 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP9_MOUSE
θ value	7.79185e-36 (rank : 36)	NC score	0.855882 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP9_HUMAN
θ value	1.32909e-35 (rank : 37)	NC score	0.865027 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP7_HUMAN
θ value	1.9192e-34 (rank : 38)	NC score	0.959927 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP21_MOUSE
θ value	2.05525e-28 (rank : 39)	NC score	0.926989 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP21_HUMAN
θ value	1.73987e-27 (rank : 40)	NC score	0.928368 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

VTNC_HUMAN
θ value	5.08577e-11 (rank : 41)	NC score	0.705420 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	43
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

VTNC_MOUSE
θ value	1.133e-10 (rank : 42)	NC score	0.732637 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

HEMO_HUMAN
θ value	1.47974e-10 (rank : 43)	NC score	0.688055 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

HEMO_MOUSE
θ value	1.29631e-06 (rank : 44)	NC score	0.616225 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q91X72, P97824, Q8WUP0	Gene names	Hpx, Hpxn
Domain Architecture
Description	Hemopexin precursor.

PRG4_HUMAN
θ value	7.1131e-05 (rank : 45)	NC score	0.301061 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	764	Shared Neighborhood Hits	43
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	0.00228821 (rank : 46)	NC score	0.364375 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	624	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRD13_HUMAN
θ value	0.0330416 (rank : 47)	NC score	0.000728 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	716	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4Q3, Q5TGC1	Gene names	PRDM13, PFM10
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 13 (PR domain-containing protein 13).

ADA19_HUMAN
θ value	0.62314 (rank : 48)	NC score	0.005282 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	381	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

NR4A3_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.003259 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

ATS13_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.058031 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	43
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

STON2_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.008086 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

ATS5_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.009657 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

HCN3_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.002969 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

MORN1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.006322 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

ATS7_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.009088 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	169	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

MARK4_MOUSE
θ value	6.88961 (rank : 56)	NC score	-0.005635 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	898	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

AMZ1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.004591 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q400G9, Q8TF51	Gene names	AMZ1, KIAA1950
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

ATS12_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.009660 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	251	Shared Neighborhood Hits	15
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.009831 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	220	Shared Neighborhood Hits	15
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS2_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.017359 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.017018 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.014737 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS8_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.008108 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

JADE2_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.001932 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	560	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

NMDE3_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.000759 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

FINC_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.053683 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.053259 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MPRI_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.051524 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MPRI_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.052821 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

SEL1L_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.078470 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.076750 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

Hits sorted by NC score

MMP11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_MOUSE
NC score	0.998750 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	48
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP25_HUMAN
NC score	0.985368 (rank : 3)	θ value	4.82422e-78 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPA2, Q9H3Q0	Gene names	MMP25, MT6MMP
Domain Architecture
Description	Matrix metalloproteinase-25 precursor (EC 3.4.24.-) (MMP-25) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (Leukolysin).

MMP17_HUMAN
NC score	0.983197 (rank : 4)	θ value	1.60597e-73 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULZ9, Q14850	Gene names	MMP17, MT4MMP
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP17_MOUSE
NC score	0.983108 (rank : 5)	θ value	2.64714e-76 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MMP24_MOUSE
NC score	0.981753 (rank : 6)	θ value	1.31072e-83 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP14_HUMAN
NC score	0.981097 (rank : 7)	θ value	9.7205e-79 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

MMP24_HUMAN
NC score	0.981000 (rank : 8)	θ value	3.81361e-83 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP14_MOUSE
NC score	0.980969 (rank : 9)	θ value	7.44272e-79 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P53690, O08645, O35369	Gene names	Mmp14, Mtmmp
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP-X1) (MT-MMP).

MMP16_HUMAN
NC score	0.978581 (rank : 10)	θ value	6.30065e-78 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP16_MOUSE
NC score	0.978546 (rank : 11)	θ value	4.82422e-78 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP28_HUMAN
NC score	0.977685 (rank : 12)	θ value	5.37103e-53 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP15_HUMAN
NC score	0.976813 (rank : 13)	θ value	1.31376e-75 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MMP15_MOUSE
NC score	0.976448 (rank : 14)	θ value	2.31901e-72 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP19_HUMAN
NC score	0.974235 (rank : 15)	θ value	2.48917e-58 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q99542, O15278, O95606, Q99580	Gene names	MMP19, MMP18, RASI
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI) (MMP-18).

MMP12_HUMAN
NC score	0.974012 (rank : 16)	θ value	5.54529e-58 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP10_MOUSE
NC score	0.973997 (rank : 17)	θ value	1.6097e-65 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	49
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP3_MOUSE
NC score	0.973561 (rank : 18)	θ value	7.71989e-68 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP19_MOUSE
NC score	0.973323 (rank : 19)	θ value	3.71957e-54 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHI0, Q8C360	Gene names	Mmp19, Rasi
Domain Architecture
Description	Matrix metalloproteinase-19 precursor (EC 3.4.24.-) (MMP-19) (Matrix metalloproteinase RASI).

MMP8_MOUSE
NC score	0.973219 (rank : 20)	θ value	1.31987e-59 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

MMP13_HUMAN
NC score	0.972777 (rank : 21)	θ value	9.1404e-61 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP3_HUMAN
NC score	0.972562 (rank : 22)	θ value	4.23606e-66 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP12_MOUSE
NC score	0.972551 (rank : 23)	θ value	5.73848e-55 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP10_HUMAN
NC score	0.972409 (rank : 24)	θ value	1.50663e-63 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	46
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP8_HUMAN
NC score	0.972137 (rank : 25)	θ value	3.84025e-59 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	47
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP20_HUMAN
NC score	0.971564 (rank : 26)	θ value	2.48917e-58 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP1_HUMAN
NC score	0.971521 (rank : 27)	θ value	1.6097e-65 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	46
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP20_MOUSE
NC score	0.971127 (rank : 28)	θ value	2.7521e-57 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP13_MOUSE
NC score	0.971108 (rank : 29)	θ value	4.24587e-58 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP1A_MOUSE
NC score	0.969709 (rank : 30)	θ value	1.15626e-55 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP1B_MOUSE
NC score	0.967449 (rank : 31)	θ value	6.56568e-51 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP26_HUMAN
NC score	0.961959 (rank : 32)	θ value	4.88048e-38 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP7_HUMAN
NC score	0.959927 (rank : 33)	θ value	1.9192e-34 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_MOUSE
NC score	0.958962 (rank : 34)	θ value	7.79185e-36 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP21_HUMAN
NC score	0.928368 (rank : 35)	θ value	1.73987e-27 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP21_MOUSE
NC score	0.926989 (rank : 36)	θ value	2.05525e-28 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP2_MOUSE
NC score	0.900936 (rank : 37)	θ value	8.59492e-43 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP2_HUMAN
NC score	0.900465 (rank : 38)	θ value	4.2656e-42 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP9_HUMAN
NC score	0.865027 (rank : 39)	θ value	1.32909e-35 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
NC score	0.855882 (rank : 40)	θ value	7.79185e-36 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

VTNC_MOUSE
NC score	0.732637 (rank : 41)	θ value	1.133e-10 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

VTNC_HUMAN
NC score	0.705420 (rank : 42)	θ value	5.08577e-11 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	43
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

HEMO_HUMAN
NC score	0.688055 (rank : 43)	θ value	1.47974e-10 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

HEMO_MOUSE
NC score	0.616225 (rank : 44)	θ value	1.29631e-06 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q91X72, P97824, Q8WUP0	Gene names	Hpx, Hpxn
Domain Architecture
Description	Hemopexin precursor.

PRG4_MOUSE
NC score	0.364375 (rank : 45)	θ value	0.00228821 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	624	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.301061 (rank : 46)	θ value	7.1131e-05 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	764	Shared Neighborhood Hits	43
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SEL1L_HUMAN
NC score	0.078470 (rank : 47)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
NC score	0.076750 (rank : 48)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

ATS13_HUMAN
NC score	0.058031 (rank : 49)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	43
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

FINC_HUMAN
NC score	0.053683 (rank : 50)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.053259 (rank : 51)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MPRI_MOUSE
NC score	0.052821 (rank : 52)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

MPRI_HUMAN
NC score	0.051524 (rank : 53)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

ATS2_HUMAN
NC score	0.017359 (rank : 54)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.017018 (rank : 55)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
NC score	0.014737 (rank : 56)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS12_MOUSE
NC score	0.009831 (rank : 57)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	220	Shared Neighborhood Hits	15
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_HUMAN
NC score	0.009660 (rank : 58)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	251	Shared Neighborhood Hits	15
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS5_MOUSE
NC score	0.009657 (rank : 59)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS7_HUMAN
NC score	0.009088 (rank : 60)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	169	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS8_MOUSE
NC score	0.008108 (rank : 61)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

STON2_MOUSE
NC score	0.008086 (rank : 62)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

MORN1_HUMAN
NC score	0.006322 (rank : 63)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

ADA19_HUMAN
NC score	0.005282 (rank : 64)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	381	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

AMZ1_HUMAN
NC score	0.004591 (rank : 65)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q400G9, Q8TF51	Gene names	AMZ1, KIAA1950
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

NR4A3_HUMAN
NC score	0.003259 (rank : 66)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

HCN3_HUMAN
NC score	0.002969 (rank : 67)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

JADE2_MOUSE
NC score	0.001932 (rank : 68)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	560	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

NMDE3_MOUSE
NC score	0.000759 (rank : 69)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

PRD13_HUMAN
NC score	0.000728 (rank : 70)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	716	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4Q3, Q5TGC1	Gene names	PRDM13, PFM10
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 13 (PR domain-containing protein 13).

MARK4_MOUSE
NC score	-0.005635 (rank : 71)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	898	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).