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Network neighborhood for query Sequence : PSD4_MOUSE

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PSD4_MOUSE
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSD4_HUMAN
θ value	0 (rank : 1)	NC score	0.970280 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD3_HUMAN
θ value	1.8752e-114 (rank : 3)	NC score	0.956069 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CYH2_HUMAN
θ value	1.05554e-24 (rank : 4)	NC score	0.727903 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	5.23862e-24 (rank : 5)	NC score	0.726804 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_MOUSE
θ value	8.93572e-24 (rank : 6)	NC score	0.722236 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH1_MOUSE
θ value	4.43474e-23 (rank : 7)	NC score	0.724219 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	176	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
θ value	5.79196e-23 (rank : 8)	NC score	0.721127 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_HUMAN
θ value	9.87957e-23 (rank : 9)	NC score	0.725632 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	137	Shared Neighborhood Hits	31
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH4_MOUSE
θ value	2.20094e-22 (rank : 10)	NC score	0.720450 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
θ value	1.42661e-21 (rank : 11)	NC score	0.719851 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	135	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

IQEC1_HUMAN
θ value	8.65492e-19 (rank : 12)	NC score	0.701152 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	1.47631e-18 (rank : 13)	NC score	0.701455 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

GBF1_HUMAN
θ value	3.28887e-18 (rank : 14)	NC score	0.720633 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

BIG1_HUMAN
θ value	9.56915e-18 (rank : 15)	NC score	0.703223 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

IQEC3_HUMAN
θ value	2.7842e-17 (rank : 16)	NC score	0.705578 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	2.7842e-17 (rank : 17)	NC score	0.697697 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC2_MOUSE
θ value	6.85773e-16 (rank : 18)	NC score	0.657599 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	417	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
θ value	1.52774e-15 (rank : 19)	NC score	0.656246 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	403	Shared Neighborhood Hits	29
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

BIG2_HUMAN
θ value	2.60593e-15 (rank : 20)	NC score	0.691203 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

SPTN2_HUMAN
θ value	6.64225e-11 (rank : 21)	NC score	0.152628 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	535	Shared Neighborhood Hits	15
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTB2_MOUSE
θ value	2.79066e-09 (rank : 22)	NC score	0.131273 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_HUMAN
θ value	4.76016e-09 (rank : 23)	NC score	0.130194 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	748	Shared Neighborhood Hits	22
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

TIAM1_HUMAN
θ value	1.69304e-06 (rank : 24)	NC score	0.145109 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SPTN4_HUMAN
θ value	2.88788e-06 (rank : 25)	NC score	0.137120 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	570	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

FBX8_HUMAN
θ value	1.09739e-05 (rank : 26)	NC score	0.614144 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	1.09739e-05 (rank : 27)	NC score	0.615475 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

TIAM1_MOUSE
θ value	1.43324e-05 (rank : 28)	NC score	0.139562 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PKHA6_MOUSE
θ value	0.0736092 (rank : 29)	NC score	0.190369 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	591	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_HUMAN
θ value	0.163984 (rank : 30)	NC score	0.197075 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SMAL1_MOUSE
θ value	0.163984 (rank : 31)	NC score	0.023608 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

PUNC_HUMAN
θ value	0.279714 (rank : 32)	NC score	0.012666 (rank : 97)
Query Neighborhood Hits	78	Target Neighborhood Hits	449	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CNKR1_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.236210 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	154	Shared Neighborhood Hits	20
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PLEK_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.186479 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

JPH4_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.018914 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

PLEK_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.189861 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	110	Shared Neighborhood Hits	24
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

LAMA1_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.011081 (rank : 105)
Query Neighborhood Hits	78	Target Neighborhood Hits	838	Shared Neighborhood Hits	8
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

CA156_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.028579 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZ09, Q810I8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf156 homolog.

DLGP1_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.014835 (rank : 94)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

HOOK2_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.020186 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	714	Shared Neighborhood Hits	12
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

MORC1_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.015181 (rank : 93)
Query Neighborhood Hits	78	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVL5	Gene names	Morc1, Morc
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 1 (Protein microrchidia).

MTMR3_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.012421 (rank : 99)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

PUNC_MOUSE
θ value	1.81305 (rank : 43)	NC score	0.010636 (rank : 106)
Query Neighborhood Hits	78	Target Neighborhood Hits	501	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

WEE1_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.003064 (rank : 116)
Query Neighborhood Hits	78	Target Neighborhood Hits	777	Shared Neighborhood Hits	6
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

CBP_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.011482 (rank : 103)
Query Neighborhood Hits	78	Target Neighborhood Hits	941	Shared Neighborhood Hits	12
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EDD1_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.012521 (rank : 98)
Query Neighborhood Hits	78	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

PKHA5_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.134708 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PLEK2_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.126504 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

TMAP1_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.029232 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

GPI8_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.018839 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXY9, Q8BH63	Gene names	Pigk
Domain Architecture
Description	GPI-anchor transamidase precursor (EC 3.-.-.-) (GPI transamidase) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K).

HEMGN_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.021142 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

BCL6B_HUMAN
θ value	4.03905 (rank : 52)	NC score	-0.002127 (rank : 125)
Query Neighborhood Hits	78	Target Neighborhood Hits	855	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N143, Q6PCB4	Gene names	BCL6B, BAZF, ZNF62
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62).

DGKH_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.037617 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

NPBL_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.015479 (rank : 92)
Query Neighborhood Hits	78	Target Neighborhood Hits	1041	Shared Neighborhood Hits	17
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PARP9_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.012823 (rank : 96)
Query Neighborhood Hits	78	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

ZN688_HUMAN
θ value	4.03905 (rank : 56)	NC score	-0.001567 (rank : 123)
Query Neighborhood Hits	78	Target Neighborhood Hits	873	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

AHTF1_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.012398 (rank : 100)
Query Neighborhood Hits	78	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

FER_HUMAN
θ value	5.27518 (rank : 58)	NC score	-0.001950 (rank : 124)
Query Neighborhood Hits	78	Target Neighborhood Hits	1278	Shared Neighborhood Hits	9
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

GON4L_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.011481 (rank : 104)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LEO1_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.004704 (rank : 113)
Query Neighborhood Hits	78	Target Neighborhood Hits	958	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAPK2_HUMAN
θ value	5.27518 (rank : 61)	NC score	-0.000756 (rank : 121)
Query Neighborhood Hits	78	Target Neighborhood Hits	844	Shared Neighborhood Hits	6
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

MAPK2_MOUSE
θ value	5.27518 (rank : 62)	NC score	-0.000746 (rank : 120)
Query Neighborhood Hits	78	Target Neighborhood Hits	831	Shared Neighborhood Hits	6
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

PLEK2_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.124819 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

E41LB_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.004159 (rank : 115)
Query Neighborhood Hits	78	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

GLI1_MOUSE
θ value	6.88961 (rank : 65)	NC score	-0.001484 (rank : 122)
Query Neighborhood Hits	78	Target Neighborhood Hits	785	Shared Neighborhood Hits	5
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

LRSM1_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.001949 (rank : 118)
Query Neighborhood Hits	78	Target Neighborhood Hits	1078	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

NT5D1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.012309 (rank : 101)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TFE4, Q6XYD5	Gene names	NT5DC1
Domain Architecture	No domain graphic available
Description	5'-nucleotidase domain-containing protein 1.

PER1_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.006397 (rank : 109)
Query Neighborhood Hits	78	Target Neighborhood Hits	215	Shared Neighborhood Hits	4
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PO3F4_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.005134 (rank : 111)
Query Neighborhood Hits	78	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	P62515, P25216	Gene names	Pou3f4, Brn-4, Brn4, Otf9
Domain Architecture	No domain graphic available
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

GOGA5_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.012902 (rank : 95)
Query Neighborhood Hits	78	Target Neighborhood Hits	1434	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

IRK3_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.002651 (rank : 117)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

JIP1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.006699 (rank : 107)
Query Neighborhood Hits	78	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KIF3A_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.005653 (rank : 110)
Query Neighborhood Hits	78	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

PCSK4_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.004221 (rank : 114)
Query Neighborhood Hits	78	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

PO3F4_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.004718 (rank : 112)
Query Neighborhood Hits	78	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

RAI14_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.006413 (rank : 108)
Query Neighborhood Hits	78	Target Neighborhood Hits	1505	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RP1L1_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.011672 (rank : 102)
Query Neighborhood Hits	78	Target Neighborhood Hits	1072	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SPEG_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.001061 (rank : 119)
Query Neighborhood Hits	78	Target Neighborhood Hits	1959	Shared Neighborhood Hits	20
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

3BP2_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.102625 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.106412 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACTN1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.057275 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.057486 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.055542 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.055549 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.056698 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	272	Shared Neighborhood Hits	4
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.056305 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	265	Shared Neighborhood Hits	4
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.057029 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.057069 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	276	Shared Neighborhood Hits	6
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ANLN_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.103394 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	222	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANLN_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.084580 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CENB2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.060901 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	425	Shared Neighborhood Hits	20
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.055868 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CLMN_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.057458 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CLMN_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.057852 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CNKR2_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.111930 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.112929 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.101546 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.106488 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GNRP_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.061900 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.059819 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

MILK1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.051524 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.055317 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	788	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.051133 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	457	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MTMR5_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.050477 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

PKHA1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.146341 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.142621 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.115399 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.131289 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.118447 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.128252 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHB1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.050180 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB2_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.054655 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB2_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.053973 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

RASA1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.072352 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	258	Shared Neighborhood Hits	17
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RHG25_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.072691 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	550	Shared Neighborhood Hits	24
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.078072 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	492	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SMOO_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.054654 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	391	Shared Neighborhood Hits	11
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SPTA1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.058505 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.060313 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	675	Shared Neighborhood Hits	11
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.054896 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	888	Shared Neighborhood Hits	10
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SPTB1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.080656 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	541	Shared Neighborhood Hits	9
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.079714 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	543	Shared Neighborhood Hits	10
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN5_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.071172 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	674	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SWP70_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.072075 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	973	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.063736 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	1097	Shared Neighborhood Hits	27
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

Hits sorted by NC score

PSD4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD4_HUMAN
NC score	0.970280 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD3_HUMAN
NC score	0.956069 (rank : 3)	θ value	1.8752e-114 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CYH2_HUMAN
NC score	0.727903 (rank : 4)	θ value	1.05554e-24 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.726804 (rank : 5)	θ value	5.23862e-24 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
NC score	0.725632 (rank : 6)	θ value	9.87957e-23 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	137	Shared Neighborhood Hits	31
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_MOUSE
NC score	0.724219 (rank : 7)	θ value	4.43474e-23 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	176	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_MOUSE
NC score	0.722236 (rank : 8)	θ value	8.93572e-24 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH1_HUMAN
NC score	0.721127 (rank : 9)	θ value	5.79196e-23 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

GBF1_HUMAN
NC score	0.720633 (rank : 10)	θ value	3.28887e-18 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

CYH4_MOUSE
NC score	0.720450 (rank : 11)	θ value	2.20094e-22 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.719851 (rank : 12)	θ value	1.42661e-21 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	135	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

IQEC3_HUMAN
NC score	0.705578 (rank : 13)	θ value	2.7842e-17 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

BIG1_HUMAN
NC score	0.703223 (rank : 14)	θ value	9.56915e-18 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

IQEC1_MOUSE
NC score	0.701455 (rank : 15)	θ value	1.47631e-18 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC1_HUMAN
NC score	0.701152 (rank : 16)	θ value	8.65492e-19 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC3_MOUSE
NC score	0.697697 (rank : 17)	θ value	2.7842e-17 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

BIG2_HUMAN
NC score	0.691203 (rank : 18)	θ value	2.60593e-15 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

IQEC2_MOUSE
NC score	0.657599 (rank : 19)	θ value	6.85773e-16 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	417	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.656246 (rank : 20)	θ value	1.52774e-15 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	403	Shared Neighborhood Hits	29
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

FBX8_MOUSE
NC score	0.615475 (rank : 21)	θ value	1.09739e-05 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX8_HUMAN
NC score	0.614144 (rank : 22)	θ value	1.09739e-05 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

CNKR1_HUMAN
NC score	0.236210 (rank : 23)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	154	Shared Neighborhood Hits	20
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA6_HUMAN
NC score	0.197075 (rank : 24)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.190369 (rank : 25)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	591	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK_HUMAN
NC score	0.189861 (rank : 26)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	110	Shared Neighborhood Hits	24
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
NC score	0.186479 (rank : 27)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

SPTN2_HUMAN
NC score	0.152628 (rank : 28)	θ value	6.64225e-11 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	535	Shared Neighborhood Hits	15
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

PKHA1_HUMAN
NC score	0.146341 (rank : 29)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	78	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

TIAM1_HUMAN
NC score	0.145109 (rank : 30)	θ value	1.69304e-06 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PKHA1_MOUSE
NC score	0.142621 (rank : 31)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	78	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

TIAM1_MOUSE
NC score	0.139562 (rank : 32)	θ value	1.43324e-05 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SPTN4_HUMAN
NC score	0.137120 (rank : 33)	θ value	2.88788e-06 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	570	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

PKHA5_HUMAN
NC score	0.134708 (rank : 34)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA2_MOUSE
NC score	0.131289 (rank : 35)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	78	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

SPTB2_MOUSE
NC score	0.131273 (rank : 36)	θ value	2.79066e-09 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_HUMAN
NC score	0.130194 (rank : 37)	θ value	4.76016e-09 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	748	Shared Neighborhood Hits	22
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

PKHA4_MOUSE
NC score	0.128252 (rank : 38)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	78	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK2_MOUSE
NC score	0.126504 (rank : 39)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.124819 (rank : 40)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PKHA4_HUMAN
NC score	0.118447 (rank : 41)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	78	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA2_HUMAN
NC score	0.115399 (rank : 42)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	78	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

CNKR2_MOUSE
NC score	0.112929 (rank : 43)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.111930 (rank : 44)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_MOUSE
NC score	0.106488 (rank : 45)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	78	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

3BP2_MOUSE
NC score	0.106412 (rank : 46)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ANLN_HUMAN
NC score	0.103394 (rank : 47)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	222	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

3BP2_HUMAN
NC score	0.102625 (rank : 48)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

DAPP1_HUMAN
NC score	0.101546 (rank : 49)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	78	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ANLN_MOUSE
NC score	0.084580 (rank : 50)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SPTB1_HUMAN
NC score	0.080656 (rank : 51)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	78	Target Neighborhood Hits	541	Shared Neighborhood Hits	9
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
NC score	0.079714 (rank : 52)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	78	Target Neighborhood Hits	543	Shared Neighborhood Hits	10
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

RHG25_MOUSE
NC score	0.078072 (rank : 53)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	78	Target Neighborhood Hits	492	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.072691 (rank : 54)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	78	Target Neighborhood Hits	550	Shared Neighborhood Hits	24
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RASA1_HUMAN
NC score	0.072352 (rank : 55)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	78	Target Neighborhood Hits	258	Shared Neighborhood Hits	17
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SWP70_HUMAN
NC score	0.072075 (rank : 56)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	78	Target Neighborhood Hits	973	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SPTN5_HUMAN
NC score	0.071172 (rank : 57)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	78	Target Neighborhood Hits	674	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SWP70_MOUSE
NC score	0.063736 (rank : 58)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	78	Target Neighborhood Hits	1097	Shared Neighborhood Hits	27
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GNRP_HUMAN
NC score	0.061900 (rank : 59)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	78	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

CENB2_HUMAN
NC score	0.060901 (rank : 60)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	425	Shared Neighborhood Hits	20
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

SPTA1_MOUSE
NC score	0.060313 (rank : 61)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	78	Target Neighborhood Hits	675	Shared Neighborhood Hits	11
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

GNRP_MOUSE
NC score	0.059819 (rank : 62)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	78	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

SPTA1_HUMAN
NC score	0.058505 (rank : 63)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	78	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CLMN_MOUSE
NC score	0.057852 (rank : 64)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	78	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

ACTN1_MOUSE
NC score	0.057486 (rank : 65)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

CLMN_HUMAN
NC score	0.057458 (rank : 66)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	78	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

ACTN1_HUMAN
NC score	0.057275 (rank : 67)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN4_MOUSE
NC score	0.057069 (rank : 68)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	276	Shared Neighborhood Hits	6
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_HUMAN
NC score	0.057029 (rank : 69)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN3_HUMAN
NC score	0.056698 (rank : 70)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	272	Shared Neighborhood Hits	4
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
NC score	0.056305 (rank : 71)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	265	Shared Neighborhood Hits	4
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

CENB5_HUMAN
NC score	0.055868 (rank : 72)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	78	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ACTN2_MOUSE
NC score	0.055549 (rank : 73)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_HUMAN
NC score	0.055542 (rank : 74)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

MILK1_MOUSE
NC score	0.055317 (rank : 75)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	78	Target Neighborhood Hits	788	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SPTA2_HUMAN
NC score	0.054896 (rank : 76)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	78	Target Neighborhood Hits	888	Shared Neighborhood Hits	10
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

PKHB2_HUMAN
NC score	0.054655 (rank : 77)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

SMOO_HUMAN
NC score	0.054654 (rank : 78)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	78	Target Neighborhood Hits	391	Shared Neighborhood Hits	11
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

PKHB2_MOUSE
NC score	0.053973 (rank : 79)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	78	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

MILK1_HUMAN
NC score	0.051524 (rank : 80)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	78	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
NC score	0.051133 (rank : 81)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	78	Target Neighborhood Hits	457	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MTMR5_HUMAN
NC score	0.050477 (rank : 82)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	78	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

PKHB1_HUMAN
NC score	0.050180 (rank : 83)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

DGKH_HUMAN
NC score	0.037617 (rank : 84)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

TMAP1_HUMAN
NC score	0.029232 (rank : 85)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

CA156_MOUSE
NC score	0.028579 (rank : 86)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZ09, Q810I8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf156 homolog.

SMAL1_MOUSE
NC score	0.023608 (rank : 87)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

HEMGN_HUMAN
NC score	0.021142 (rank : 88)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

HOOK2_HUMAN
NC score	0.020186 (rank : 89)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	714	Shared Neighborhood Hits	12
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

JPH4_HUMAN
NC score	0.018914 (rank : 90)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

GPI8_MOUSE
NC score	0.018839 (rank : 91)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXY9, Q8BH63	Gene names	Pigk
Domain Architecture
Description	GPI-anchor transamidase precursor (EC 3.-.-.-) (GPI transamidase) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K).

NPBL_MOUSE
NC score	0.015479 (rank : 92)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	1041	Shared Neighborhood Hits	17
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MORC1_MOUSE
NC score	0.015181 (rank : 93)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVL5	Gene names	Morc1, Morc
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 1 (Protein microrchidia).

DLGP1_MOUSE
NC score	0.014835 (rank : 94)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

GOGA5_MOUSE
NC score	0.012902 (rank : 95)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	1434	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

PARP9_HUMAN
NC score	0.012823 (rank : 96)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PUNC_HUMAN
NC score	0.012666 (rank : 97)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	449	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

EDD1_MOUSE
NC score	0.012521 (rank : 98)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

MTMR3_MOUSE
NC score	0.012421 (rank : 99)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

AHTF1_MOUSE
NC score	0.012398 (rank : 100)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

NT5D1_HUMAN
NC score	0.012309 (rank : 101)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TFE4, Q6XYD5	Gene names	NT5DC1
Domain Architecture	No domain graphic available
Description	5'-nucleotidase domain-containing protein 1.

RP1L1_HUMAN
NC score	0.011672 (rank : 102)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	1072	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CBP_HUMAN
NC score	0.011482 (rank : 103)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	941	Shared Neighborhood Hits	12
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GON4L_MOUSE
NC score	0.011481 (rank : 104)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LAMA1_MOUSE
NC score	0.011081 (rank : 105)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	838	Shared Neighborhood Hits	8
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

PUNC_MOUSE
NC score	0.010636 (rank : 106)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	501	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

JIP1_HUMAN
NC score	0.006699 (rank : 107)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

RAI14_MOUSE
NC score	0.006413 (rank : 108)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	1505	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

PER1_HUMAN
NC score	0.006397 (rank : 109)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	215	Shared Neighborhood Hits	4
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

KIF3A_MOUSE
NC score	0.005653 (rank : 110)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

PO3F4_MOUSE
NC score	0.005134 (rank : 111)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	P62515, P25216	Gene names	Pou3f4, Brn-4, Brn4, Otf9
Domain Architecture	No domain graphic available
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

PO3F4_HUMAN
NC score	0.004718 (rank : 112)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

LEO1_HUMAN
NC score	0.004704 (rank : 113)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	958	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PCSK4_MOUSE
NC score	0.004221 (rank : 114)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

E41LB_HUMAN
NC score	0.004159 (rank : 115)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

WEE1_HUMAN
NC score	0.003064 (rank : 116)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	777	Shared Neighborhood Hits	6
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

IRK3_HUMAN
NC score	0.002651 (rank : 117)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

LRSM1_HUMAN
NC score	0.001949 (rank : 118)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	1078	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SPEG_MOUSE
NC score	0.001061 (rank : 119)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	1959	Shared Neighborhood Hits	20
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MAPK2_MOUSE
NC score	-0.000746 (rank : 120)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	831	Shared Neighborhood Hits	6
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

MAPK2_HUMAN
NC score	-0.000756 (rank : 121)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	844	Shared Neighborhood Hits	6
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

GLI1_MOUSE
NC score	-0.001484 (rank : 122)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	785	Shared Neighborhood Hits	5
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

ZN688_HUMAN
NC score	-0.001567 (rank : 123)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	873	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

FER_HUMAN
NC score	-0.001950 (rank : 124)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	1278	Shared Neighborhood Hits	9
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

BCL6B_HUMAN
NC score	-0.002127 (rank : 125)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	855	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N143, Q6PCB4	Gene names	BCL6B, BAZF, ZNF62
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62).