Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MTMR5_HUMAN

For an explanation of this page, click here

MTMR5_HUMAN
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MTMR5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
θ value	0 (rank : 2)	NC score	0.984271 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	86
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

MTMR3_MOUSE
θ value	6.15952e-41 (rank : 3)	NC score	0.713203 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

MTMR3_HUMAN
θ value	1.05066e-40 (rank : 4)	NC score	0.640529 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MTMR2_HUMAN
θ value	3.86705e-35 (rank : 5)	NC score	0.706787 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q13614, Q9UPS9	Gene names	MTMR2, KIAA1073
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR2_MOUSE
θ value	8.61488e-35 (rank : 6)	NC score	0.706977 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2D1, Q8VHA7	Gene names	Mtmr2
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTM1_MOUSE
θ value	5.584e-34 (rank : 7)	NC score	0.701921 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2C5	Gene names	Mtm1
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTM1_HUMAN
θ value	1.6247e-33 (rank : 8)	NC score	0.701977 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTMR7_MOUSE
θ value	1.6247e-33 (rank : 9)	NC score	0.698999 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR1_HUMAN
θ value	6.17384e-33 (rank : 10)	NC score	0.699091 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q13613, Q9UBX6, Q9UEM0, Q9UQD5	Gene names	MTMR1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR7_HUMAN
θ value	8.06329e-33 (rank : 11)	NC score	0.698153 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR1_MOUSE
θ value	1.37539e-32 (rank : 12)	NC score	0.697743 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2C4	Gene names	Mtmr1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR9_MOUSE
θ value	1.33217e-27 (rank : 13)	NC score	0.698169 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

MYCPP_HUMAN
θ value	8.63488e-27 (rank : 14)	NC score	0.515996 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

MTMR6_HUMAN
θ value	1.92365e-26 (rank : 15)	NC score	0.694376 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y217, Q86TB7, Q86YH4, Q96P80	Gene names	MTMR6
Domain Architecture
Description	Myotubularin-related protein 6 (EC 3.1.3.-).

MTMR9_HUMAN
θ value	1.92365e-26 (rank : 16)	NC score	0.695926 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	Q96QG7, Q52LU3, Q8WW11, Q96QG6, Q9NX50	Gene names	MTMR9, C8orf9, MTMR8
Domain Architecture
Description	Myotubularin-related protein 9.

RA6I1_MOUSE
θ value	9.87957e-23 (rank : 17)	NC score	0.484147 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_HUMAN
θ value	1.6852e-22 (rank : 18)	NC score	0.482008 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

DEN4C_HUMAN
θ value	3.63628e-17 (rank : 19)	NC score	0.480779 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

DEN2A_MOUSE
θ value	8.38298e-14 (rank : 20)	NC score	0.429965 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2D_HUMAN
θ value	3.18553e-13 (rank : 21)	NC score	0.445246 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2C_HUMAN
θ value	4.16044e-13 (rank : 22)	NC score	0.429872 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q68D51, Q5TCX6, Q6P3R3	Gene names	DENND2C
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2D_MOUSE
θ value	7.09661e-13 (rank : 23)	NC score	0.445171 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VV4, Q3U028, Q9D831	Gene names	Dennd2d
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

ST5_MOUSE
θ value	7.09661e-13 (rank : 24)	NC score	0.417092 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

DEN2C_MOUSE
θ value	1.2105e-12 (rank : 25)	NC score	0.422807 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN1A_MOUSE
θ value	2.69671e-12 (rank : 26)	NC score	0.434877 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN2A_HUMAN
θ value	4.59992e-12 (rank : 27)	NC score	0.419658 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN1A_HUMAN
θ value	6.00763e-12 (rank : 28)	NC score	0.431701 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ST5_HUMAN
θ value	7.84624e-12 (rank : 29)	NC score	0.412116 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

PHLB1_MOUSE
θ value	3.08544e-08 (rank : 30)	NC score	0.191988 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	678	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_HUMAN
θ value	3.08544e-08 (rank : 31)	NC score	0.158791 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	964	Shared Neighborhood Hits	46
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	1.17247e-07 (rank : 32)	NC score	0.152151 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	1016	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB1_HUMAN
θ value	7.59969e-07 (rank : 33)	NC score	0.164497 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	1038	Shared Neighborhood Hits	45
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

DAPP1_MOUSE
θ value	0.00020696 (rank : 34)	NC score	0.145632 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	225	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
θ value	0.000461057 (rank : 35)	NC score	0.142261 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	227	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CYH3_MOUSE
θ value	0.00134147 (rank : 36)	NC score	0.149573 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	50
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

C43BP_MOUSE
θ value	0.00298849 (rank : 37)	NC score	0.164973 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CYH4_HUMAN
θ value	0.00298849 (rank : 38)	NC score	0.146922 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	0.00298849 (rank : 39)	NC score	0.146838 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

FGD6_MOUSE
θ value	0.00298849 (rank : 40)	NC score	0.080143 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

C43BP_HUMAN
θ value	0.00390308 (rank : 41)	NC score	0.159852 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

FGD6_HUMAN
θ value	0.00509761 (rank : 42)	NC score	0.078053 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	237	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

CYH1_HUMAN
θ value	0.00665767 (rank : 43)	NC score	0.132794 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

OSBL9_HUMAN
θ value	0.00869519 (rank : 44)	NC score	0.117949 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

CYH1_MOUSE
θ value	0.0113563 (rank : 45)	NC score	0.129878 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

MYO10_HUMAN
θ value	0.0113563 (rank : 46)	NC score	0.048007 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	920	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PLEK_HUMAN
θ value	0.0113563 (rank : 47)	NC score	0.161740 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

CYH2_HUMAN
θ value	0.0148317 (rank : 48)	NC score	0.133267 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	175	Shared Neighborhood Hits	48
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	0.0148317 (rank : 49)	NC score	0.133242 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	171	Shared Neighborhood Hits	48
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

SWP70_HUMAN
θ value	0.0148317 (rank : 50)	NC score	0.090147 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	973	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA1_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.148117 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	127	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	0.0193708 (rank : 52)	NC score	0.149836 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

HORN_MOUSE
θ value	0.0252991 (rank : 53)	NC score	0.036871 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

SWP70_MOUSE
θ value	0.0252991 (rank : 54)	NC score	0.087553 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	1097	Shared Neighborhood Hits	64
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CYH3_HUMAN
θ value	0.0330416 (rank : 55)	NC score	0.133601 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

K0513_MOUSE
θ value	0.0330416 (rank : 56)	NC score	0.078651 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0A7, Q80TY8, Q8BQV3, Q8C8N9, Q8CCN0	Gene names	Kiaa0513
Domain Architecture	No domain graphic available
Description	Protein KIAA0513.

PLEK_MOUSE
θ value	0.0330416 (rank : 57)	NC score	0.161849 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	109	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

CNKR1_HUMAN
θ value	0.0431538 (rank : 58)	NC score	0.107653 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA3_HUMAN
θ value	0.0431538 (rank : 59)	NC score	0.158059 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	0.0431538 (rank : 60)	NC score	0.154527 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

GAB2_MOUSE
θ value	0.0563607 (rank : 61)	NC score	0.116872 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

TBCD2_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.095476 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

CENA2_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.082604 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

GAB2_HUMAN
θ value	0.0961366 (rank : 64)	NC score	0.118587 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

K0513_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.074339 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O60268, Q8N6G0	Gene names	KIAA0513
Domain Architecture	No domain graphic available
Description	Protein KIAA0513.

CENA2_MOUSE
θ value	0.21417 (rank : 66)	NC score	0.064945 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

RASA1_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.073745 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CEND2_HUMAN
θ value	0.279714 (rank : 68)	NC score	0.051477 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

OSB11_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.079882 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

HORN_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.030748 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

OSBP1_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.071134 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CHD8_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.008884 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CNKR2_HUMAN
θ value	0.813845 (rank : 73)	NC score	0.072620 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.813845 (rank : 74)	NC score	0.072659 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

OSB11_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.072974 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PLEK2_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.131808 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLXA4_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.020866 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
θ value	1.06291 (rank : 78)	NC score	0.020885 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

SYN1_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.017040 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

DDEF2_MOUSE
θ value	1.38821 (rank : 80)	NC score	0.037278 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	625	Shared Neighborhood Hits	25
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.035088 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

PLEK2_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.130933 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLXA2_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.020635 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXA2_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.020663 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

CLAP1_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.019134 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

DDFL1_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.035997 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FARP1_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.033661 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	241	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

NMD3B_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.008393 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

GAB1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.087611 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	279	Shared Neighborhood Hits	34
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.086494 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	233	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

OSBP2_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.064313 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

SPB12_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.003788 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7P9, Q6UKZ3	Gene names	Serpinb12
Domain Architecture	No domain graphic available
Description	Serpin B12.

SYN1_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.017098 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	363	Shared Neighborhood Hits	6
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CAN7_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.012609 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CM35H_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.017803 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGN4, O95100, Q9HD97, Q9UBK4, Q9UMS9, Q9UMT0	Gene names	CD300A, CMRF35H
Domain Architecture
Description	CMRF35-H antigen precursor (CMRF35-H9) (CMRF-35-H9) (CD300a antigen) (Inhibitory receptor protein 60) (IRp60) (IRC1/IRC2) (NK inhibitory receptor).

ELF4_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.007517 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

MAML3_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.017008 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

DDEF2_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.033312 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	599	Shared Neighborhood Hits	26
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FGD4_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.031899 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

LR37B_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.006238 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	392	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

SOX6_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.015298 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.015236 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

AKT1_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.005717 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	885	Shared Neighborhood Hits	35
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

AKT1_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.005412 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	878	Shared Neighborhood Hits	35
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

GATA6_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.008826 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q61169, P97729, Q9QZK3	Gene names	Gata6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

HNF3B_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.002537 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y261, Q8WUW4, Q96DF7	Gene names	FOXA2, HNF3B, TCF3B
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

ITIH2_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.007505 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

LSM11_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.016295 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUV6	Gene names	Lsm11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

M3K14_HUMAN
θ value	5.27518 (rank : 109)	NC score	-0.002028 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	887	Shared Neighborhood Hits	9
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

RHG25_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.062389 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	550	Shared Neighborhood Hits	56
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIMB1_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.011511 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	1376	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ATS8_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.001309 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

CAC1C_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.002473 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CEND3_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.034580 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	275	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

ELOA1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.004552 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	388	Shared Neighborhood Hits	2
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GP158_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.008799 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

LRRK2_HUMAN
θ value	6.88961 (rank : 117)	NC score	-0.004725 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	1382	Shared Neighborhood Hits	9
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

LZTS1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.009080 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	532	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS1_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.008187 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	540	Shared Neighborhood Hits	10
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

RGS14_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.005013 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

AKT2_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.005718 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	878	Shared Neighborhood Hits	33
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT2_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.005794 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	875	Shared Neighborhood Hits	31
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AZI1_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.011167 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	1000	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CP2DQ_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.000270 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIM7, Q9DBJ5	Gene names	Cyp2d26, Cyp2d-26
Domain Architecture	No domain graphic available
Description	Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26).

CSPG2_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.000254 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	711	Shared Neighborhood Hits	7
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	8.99809 (rank : 126)	NC score	-0.000274 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	676	Shared Neighborhood Hits	5
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

GATA4_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.007164 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q08369, P97491, Q9QZK4	Gene names	Gata4, Gata-4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

HNRH3_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.004641 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P31942, Q9BSX1, Q9NP53, Q9NP96, Q9NPA7, Q9NPI4, Q9UFU4, Q9Y4J5	Gene names	HNRPH3
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (hnRNP 2H9).

IFT88_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.006148 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

KLF11_HUMAN
θ value	8.99809 (rank : 130)	NC score	-0.003575 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	717	Shared Neighborhood Hits	4
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_MOUSE
θ value	8.99809 (rank : 131)	NC score	-0.003568 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	714	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

LASS5_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.004643 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5B7	Gene names	LASS5
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 5.

NOL10_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.006316 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

OSB10_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.064968 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

RNF19_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.004928 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

SOX5_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.010518 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.009876 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

TCF20_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.008811 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.009894 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	396	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

UBP8_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.001616 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	751	Shared Neighborhood Hits	8
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ZN358_HUMAN
θ value	8.99809 (rank : 141)	NC score	-0.005287 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	840	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

BIG1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.053724 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.053391 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

GBF1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.053140 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

IQEC3_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.050158 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

PKHA2_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.105275 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.100241 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.061666 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	283	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.069960 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	202	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.074588 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.079613 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	556	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.077124 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	591	Shared Neighborhood Hits	54
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PSD3_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.053470 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.050477 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

RHG25_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.052113 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	492	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

Hits sorted by NC score

MTMR5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
NC score	0.984271 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	86
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

MTMR3_MOUSE
NC score	0.713203 (rank : 3)	θ value	6.15952e-41 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

MTMR2_MOUSE
NC score	0.706977 (rank : 4)	θ value	8.61488e-35 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2D1, Q8VHA7	Gene names	Mtmr2
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR2_HUMAN
NC score	0.706787 (rank : 5)	θ value	3.86705e-35 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q13614, Q9UPS9	Gene names	MTMR2, KIAA1073
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTM1_HUMAN
NC score	0.701977 (rank : 6)	θ value	1.6247e-33 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTM1_MOUSE
NC score	0.701921 (rank : 7)	θ value	5.584e-34 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2C5	Gene names	Mtm1
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTMR1_HUMAN
NC score	0.699091 (rank : 8)	θ value	6.17384e-33 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q13613, Q9UBX6, Q9UEM0, Q9UQD5	Gene names	MTMR1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR7_MOUSE
NC score	0.698999 (rank : 9)	θ value	1.6247e-33 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR9_MOUSE
NC score	0.698169 (rank : 10)	θ value	1.33217e-27 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

MTMR7_HUMAN
NC score	0.698153 (rank : 11)	θ value	8.06329e-33 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR1_MOUSE
NC score	0.697743 (rank : 12)	θ value	1.37539e-32 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2C4	Gene names	Mtmr1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR9_HUMAN
NC score	0.695926 (rank : 13)	θ value	1.92365e-26 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	Q96QG7, Q52LU3, Q8WW11, Q96QG6, Q9NX50	Gene names	MTMR9, C8orf9, MTMR8
Domain Architecture
Description	Myotubularin-related protein 9.

MTMR6_HUMAN
NC score	0.694376 (rank : 14)	θ value	1.92365e-26 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y217, Q86TB7, Q86YH4, Q96P80	Gene names	MTMR6
Domain Architecture
Description	Myotubularin-related protein 6 (EC 3.1.3.-).

MTMR3_HUMAN
NC score	0.640529 (rank : 15)	θ value	1.05066e-40 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MYCPP_HUMAN
NC score	0.515996 (rank : 16)	θ value	8.63488e-27 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

RA6I1_MOUSE
NC score	0.484147 (rank : 17)	θ value	9.87957e-23 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_HUMAN
NC score	0.482008 (rank : 18)	θ value	1.6852e-22 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

DEN4C_HUMAN
NC score	0.480779 (rank : 19)	θ value	3.63628e-17 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

DEN2D_HUMAN
NC score	0.445246 (rank : 20)	θ value	3.18553e-13 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2D_MOUSE
NC score	0.445171 (rank : 21)	θ value	7.09661e-13 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VV4, Q3U028, Q9D831	Gene names	Dennd2d
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN1A_MOUSE
NC score	0.434877 (rank : 22)	θ value	2.69671e-12 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
NC score	0.431701 (rank : 23)	θ value	6.00763e-12 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN2A_MOUSE
NC score	0.429965 (rank : 24)	θ value	8.38298e-14 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2C_HUMAN
NC score	0.429872 (rank : 25)	θ value	4.16044e-13 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q68D51, Q5TCX6, Q6P3R3	Gene names	DENND2C
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2C_MOUSE
NC score	0.422807 (rank : 26)	θ value	1.2105e-12 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2A_HUMAN
NC score	0.419658 (rank : 27)	θ value	4.59992e-12 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

ST5_MOUSE
NC score	0.417092 (rank : 28)	θ value	7.09661e-13 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

ST5_HUMAN
NC score	0.412116 (rank : 29)	θ value	7.84624e-12 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

PHLB1_MOUSE
NC score	0.191988 (rank : 30)	θ value	3.08544e-08 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	678	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

C43BP_MOUSE
NC score	0.164973 (rank : 31)	θ value	0.00298849 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PHLB1_HUMAN
NC score	0.164497 (rank : 32)	θ value	7.59969e-07 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	1038	Shared Neighborhood Hits	45
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PLEK_MOUSE
NC score	0.161849 (rank : 33)	θ value	0.0330416 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	109	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK_HUMAN
NC score	0.161740 (rank : 34)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

C43BP_HUMAN
NC score	0.159852 (rank : 35)	θ value	0.00390308 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PHLB2_HUMAN
NC score	0.158791 (rank : 36)	θ value	3.08544e-08 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	964	Shared Neighborhood Hits	46
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA3_HUMAN
NC score	0.158059 (rank : 37)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
NC score	0.154527 (rank : 38)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PHLB2_MOUSE
NC score	0.152151 (rank : 39)	θ value	1.17247e-07 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	1016	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA1_MOUSE
NC score	0.149836 (rank : 40)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CYH3_MOUSE
NC score	0.149573 (rank : 41)	θ value	0.00134147 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	50
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

PKHA1_HUMAN
NC score	0.148117 (rank : 42)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	127	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CYH4_HUMAN
NC score	0.146922 (rank : 43)	θ value	0.00298849 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
NC score	0.146838 (rank : 44)	θ value	0.00298849 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DAPP1_MOUSE
NC score	0.145632 (rank : 45)	θ value	0.00020696 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	225	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.142261 (rank : 46)	θ value	0.000461057 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	227	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CYH3_HUMAN
NC score	0.133601 (rank : 47)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_HUMAN
NC score	0.133267 (rank : 48)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	175	Shared Neighborhood Hits	48
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.133242 (rank : 49)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	171	Shared Neighborhood Hits	48
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH1_HUMAN
NC score	0.132794 (rank : 50)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

PLEK2_MOUSE
NC score	0.131808 (rank : 51)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.130933 (rank : 52)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

CYH1_MOUSE
NC score	0.129878 (rank : 53)	θ value	0.0113563 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

GAB2_HUMAN
NC score	0.118587 (rank : 54)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

OSBL9_HUMAN
NC score	0.117949 (rank : 55)	θ value	0.00869519 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

GAB2_MOUSE
NC score	0.116872 (rank : 56)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

CNKR1_HUMAN
NC score	0.107653 (rank : 57)	θ value	0.0431538 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA2_HUMAN
NC score	0.105275 (rank : 58)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
NC score	0.100241 (rank : 59)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

TBCD2_HUMAN
NC score	0.095476 (rank : 60)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

SWP70_HUMAN
NC score	0.090147 (rank : 61)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	973	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GAB1_HUMAN
NC score	0.087611 (rank : 62)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	279	Shared Neighborhood Hits	34
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SWP70_MOUSE
NC score	0.087553 (rank : 63)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	1097	Shared Neighborhood Hits	64
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GAB1_MOUSE
NC score	0.086494 (rank : 64)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	233	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CENA2_HUMAN
NC score	0.082604 (rank : 65)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

FGD6_MOUSE
NC score	0.080143 (rank : 66)	θ value	0.00298849 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

OSB11_MOUSE
NC score	0.079882 (rank : 67)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PKHA6_HUMAN
NC score	0.079613 (rank : 68)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	556	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

K0513_MOUSE
NC score	0.078651 (rank : 69)	θ value	0.0330416 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0A7, Q80TY8, Q8BQV3, Q8C8N9, Q8CCN0	Gene names	Kiaa0513
Domain Architecture	No domain graphic available
Description	Protein KIAA0513.

FGD6_HUMAN
NC score	0.078053 (rank : 70)	θ value	0.00509761 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	237	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

PKHA6_MOUSE
NC score	0.077124 (rank : 71)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	591	Shared Neighborhood Hits	54
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA5_HUMAN
NC score	0.074588 (rank : 72)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

K0513_HUMAN
NC score	0.074339 (rank : 73)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O60268, Q8N6G0	Gene names	KIAA0513
Domain Architecture	No domain graphic available
Description	Protein KIAA0513.

RASA1_HUMAN
NC score	0.073745 (rank : 74)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

OSB11_HUMAN
NC score	0.072974 (rank : 75)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

CNKR2_MOUSE
NC score	0.072659 (rank : 76)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.072620 (rank : 77)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

OSBP1_HUMAN
NC score	0.071134 (rank : 78)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PKHA4_MOUSE
NC score	0.069960 (rank : 79)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	202	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

OSB10_HUMAN
NC score	0.064968 (rank : 80)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

CENA2_MOUSE
NC score	0.064945 (rank : 81)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

OSBP2_HUMAN
NC score	0.064313 (rank : 82)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

RHG25_HUMAN
NC score	0.062389 (rank : 83)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	550	Shared Neighborhood Hits	56
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA4_HUMAN
NC score	0.061666 (rank : 84)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	283	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

BIG1_HUMAN
NC score	0.053724 (rank : 85)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

PSD3_HUMAN
NC score	0.053470 (rank : 86)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

BIG2_HUMAN
NC score	0.053391 (rank : 87)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

GBF1_HUMAN
NC score	0.053140 (rank : 88)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

RHG25_MOUSE
NC score	0.052113 (rank : 89)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	492	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND2_HUMAN
NC score	0.051477 (rank : 90)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

PSD4_MOUSE
NC score	0.050477 (rank : 91)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

IQEC3_HUMAN
NC score	0.050158 (rank : 92)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MYO10_HUMAN
NC score	0.048007 (rank : 93)	θ value	0.0113563 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	920	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

DDEF2_MOUSE
NC score	0.037278 (rank : 94)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	625	Shared Neighborhood Hits	25
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

HORN_MOUSE
NC score	0.036871 (rank : 95)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

DDFL1_HUMAN
NC score	0.035997 (rank : 96)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
NC score	0.035088 (rank : 97)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CEND3_HUMAN
NC score	0.034580 (rank : 98)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	275	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

FARP1_HUMAN
NC score	0.033661 (rank : 99)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	241	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

DDEF2_HUMAN
NC score	0.033312 (rank : 100)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	599	Shared Neighborhood Hits	26
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FGD4_MOUSE
NC score	0.031899 (rank : 101)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

HORN_HUMAN
NC score	0.030748 (rank : 102)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

PLXA4_MOUSE
NC score	0.020885 (rank : 103)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_HUMAN
NC score	0.020866 (rank : 104)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA2_MOUSE
NC score	0.020663 (rank : 105)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXA2_HUMAN
NC score	0.020635 (rank : 106)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

CLAP1_HUMAN
NC score	0.019134 (rank : 107)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

CM35H_HUMAN
NC score	0.017803 (rank : 108)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGN4, O95100, Q9HD97, Q9UBK4, Q9UMS9, Q9UMT0	Gene names	CD300A, CMRF35H
Domain Architecture
Description	CMRF35-H antigen precursor (CMRF35-H9) (CMRF-35-H9) (CD300a antigen) (Inhibitory receptor protein 60) (IRp60) (IRC1/IRC2) (NK inhibitory receptor).

SYN1_MOUSE
NC score	0.017098 (rank : 109)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	363	Shared Neighborhood Hits	6
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYN1_HUMAN
NC score	0.017040 (rank : 110)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

MAML3_HUMAN
NC score	0.017008 (rank : 111)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

LSM11_MOUSE
NC score	0.016295 (rank : 112)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUV6	Gene names	Lsm11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

SOX6_HUMAN
NC score	0.015298 (rank : 113)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.015236 (rank : 114)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

CAN7_HUMAN
NC score	0.012609 (rank : 115)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

RIMB1_MOUSE
NC score	0.011511 (rank : 116)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	1376	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

AZI1_HUMAN
NC score	0.011167 (rank : 117)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	1000	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

SOX5_HUMAN
NC score	0.010518 (rank : 118)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

TCF20_MOUSE
NC score	0.009894 (rank : 119)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	396	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

SOX5_MOUSE
NC score	0.009876 (rank : 120)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

LZTS1_HUMAN
NC score	0.009080 (rank : 121)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	532	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CHD8_HUMAN
NC score	0.008884 (rank : 122)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

GATA6_MOUSE
NC score	0.008826 (rank : 123)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q61169, P97729, Q9QZK3	Gene names	Gata6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

TCF20_HUMAN
NC score	0.008811 (rank : 124)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

GP158_MOUSE
NC score	0.008799 (rank : 125)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

NMD3B_HUMAN
NC score	0.008393 (rank : 126)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

LZTS1_MOUSE
NC score	0.008187 (rank : 127)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	540	Shared Neighborhood Hits	10
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

ELF4_MOUSE
NC score	0.007517 (rank : 128)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ITIH2_HUMAN
NC score	0.007505 (rank : 129)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

GATA4_MOUSE
NC score	0.007164 (rank : 130)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q08369, P97491, Q9QZK4	Gene names	Gata4, Gata-4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

NOL10_MOUSE
NC score	0.006316 (rank : 131)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

LR37B_HUMAN
NC score	0.006238 (rank : 132)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	392	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

IFT88_MOUSE
NC score	0.006148 (rank : 133)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

AKT2_MOUSE
NC score	0.005794 (rank : 134)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	875	Shared Neighborhood Hits	31
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT2_HUMAN
NC score	0.005718 (rank : 135)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	878	Shared Neighborhood Hits	33
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT1_HUMAN
NC score	0.005717 (rank : 136)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	885	Shared Neighborhood Hits	35
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

AKT1_MOUSE
NC score	0.005412 (rank : 137)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	878	Shared Neighborhood Hits	35
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

RGS14_HUMAN
NC score	0.005013 (rank : 138)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RNF19_MOUSE
NC score	0.004928 (rank : 139)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

LASS5_HUMAN
NC score	0.004643 (rank : 140)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5B7	Gene names	LASS5
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 5.

HNRH3_HUMAN
NC score	0.004641 (rank : 141)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P31942, Q9BSX1, Q9NP53, Q9NP96, Q9NPA7, Q9NPI4, Q9UFU4, Q9Y4J5	Gene names	HNRPH3
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (hnRNP 2H9).

ELOA1_HUMAN
NC score	0.004552 (rank : 142)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	388	Shared Neighborhood Hits	2
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

SPB12_MOUSE
NC score	0.003788 (rank : 143)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7P9, Q6UKZ3	Gene names	Serpinb12
Domain Architecture	No domain graphic available
Description	Serpin B12.

HNF3B_HUMAN
NC score	0.002537 (rank : 144)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y261, Q8WUW4, Q96DF7	Gene names	FOXA2, HNF3B, TCF3B
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

CAC1C_HUMAN
NC score	0.002473 (rank : 145)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

UBP8_HUMAN
NC score	0.001616 (rank : 146)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	751	Shared Neighborhood Hits	8
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ATS8_HUMAN
NC score	0.001309 (rank : 147)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

CP2DQ_MOUSE
NC score	0.000270 (rank : 148)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIM7, Q9DBJ5	Gene names	Cyp2d26, Cyp2d-26
Domain Architecture	No domain graphic available
Description	Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26).

CSPG2_MOUSE
NC score	0.000254 (rank : 149)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	711	Shared Neighborhood Hits	7
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
NC score	-0.000274 (rank : 150)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	676	Shared Neighborhood Hits	5
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

M3K14_HUMAN
NC score	-0.002028 (rank : 151)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	887	Shared Neighborhood Hits	9
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

KLF11_MOUSE
NC score	-0.003568 (rank : 152)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	714	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_HUMAN
NC score	-0.003575 (rank : 153)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	717	Shared Neighborhood Hits	4
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

LRRK2_HUMAN
NC score	-0.004725 (rank : 154)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	1382	Shared Neighborhood Hits	9
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

ZN358_HUMAN
NC score	-0.005287 (rank : 155)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	840	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.