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Network neighborhood for query Sequence : RNF19_MOUSE

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RNF19_MOUSE
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IBRD3_HUMAN
θ value	0 (rank : 1)	NC score	0.979497 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	0 (rank : 2)	NC score	0.996949 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

UB7I4_MOUSE
θ value	1.86321e-21 (rank : 4)	NC score	0.747369 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD2_HUMAN
θ value	9.24701e-21 (rank : 5)	NC score	0.732938 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

UB7I4_HUMAN
θ value	9.24701e-21 (rank : 6)	NC score	0.746049 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ARI1_HUMAN
θ value	1.2077e-20 (rank : 7)	NC score	0.716923 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	1.2077e-20 (rank : 8)	NC score	0.716784 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

ARI2_HUMAN
θ value	4.74913e-17 (rank : 9)	NC score	0.697484 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	1.058e-16 (rank : 10)	NC score	0.695378 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

IBRD2_MOUSE
θ value	1.38178e-16 (rank : 11)	NC score	0.718963 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

PARC_HUMAN
θ value	8.95645e-16 (rank : 12)	NC score	0.537188 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	4.91457e-14 (rank : 13)	NC score	0.522893 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	114	Shared Neighborhood Hits	33
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

RNF14_HUMAN
θ value	8.38298e-14 (rank : 14)	NC score	0.677783 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
θ value	1.86753e-13 (rank : 15)	NC score	0.677243 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF31_MOUSE
θ value	9.59137e-10 (rank : 16)	NC score	0.515025 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

UB7I1_HUMAN
θ value	1.63604e-09 (rank : 17)	NC score	0.508547 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

RNF31_HUMAN
θ value	2.79066e-09 (rank : 18)	NC score	0.512065 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	110	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UB7I1_MOUSE
θ value	3.64472e-09 (rank : 19)	NC score	0.503589 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

PRKN2_MOUSE
θ value	6.21693e-09 (rank : 20)	NC score	0.540854 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

UB7I3_MOUSE
θ value	5.26297e-08 (rank : 21)	NC score	0.544621 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

PRKN2_HUMAN
θ value	1.99992e-07 (rank : 22)	NC score	0.528703 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

UB7I3_HUMAN
θ value	5.81887e-07 (rank : 23)	NC score	0.534639 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

IBRD1_HUMAN
θ value	4.92598e-06 (rank : 24)	NC score	0.617534 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

TRI10_MOUSE
θ value	5.44631e-05 (rank : 25)	NC score	0.120292 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	285	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI22_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.097151 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI10_HUMAN
θ value	0.00665767 (rank : 27)	NC score	0.102779 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	315	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRIM3_HUMAN
θ value	0.0148317 (rank : 28)	NC score	0.129590 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	357	Shared Neighborhood Hits	50
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

MKRN1_HUMAN
θ value	0.0193708 (rank : 29)	NC score	0.140249 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	0.0193708 (rank : 30)	NC score	0.140379 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

PGCA_MOUSE
θ value	0.0252991 (rank : 31)	NC score	0.031171 (rank : 137)
Query Neighborhood Hits	96	Target Neighborhood Hits	643	Shared Neighborhood Hits	5
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MKRN4_HUMAN
θ value	0.0330416 (rank : 32)	NC score	0.144152 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

TRIM3_MOUSE
θ value	0.0330416 (rank : 33)	NC score	0.121690 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	351	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

MKRN3_MOUSE
θ value	0.0563607 (rank : 34)	NC score	0.145662 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

TRI27_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.077281 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	273	Shared Neighborhood Hits	40
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI32_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.130572 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.127608 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

MKRN2_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.127614 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

RN152_HUMAN
θ value	0.0736092 (rank : 39)	NC score	0.160989 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	0.0736092 (rank : 40)	NC score	0.161397 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

ZCH13_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.091461 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WW36	Gene names	ZCCHC13
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 13.

MKRN2_MOUSE
θ value	0.125558 (rank : 42)	NC score	0.125692 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	130	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN3_HUMAN
θ value	0.125558 (rank : 43)	NC score	0.140131 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	165	Shared Neighborhood Hits	31
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

TRI27_MOUSE
θ value	0.125558 (rank : 44)	NC score	0.074733 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	261	Shared Neighborhood Hits	36
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI35_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.086492 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	382	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI56_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.105532 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM2_HUMAN
θ value	0.125558 (rank : 47)	NC score	0.119546 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	330	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.125558 (rank : 48)	NC score	0.118860 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	331	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

FRAS1_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.032366 (rank : 136)
Query Neighborhood Hits	96	Target Neighborhood Hits	759	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TRI56_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.108182 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI42_MOUSE
θ value	0.279714 (rank : 51)	NC score	0.089727 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	316	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

FBX43_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.112945 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FRAS1_MOUSE
θ value	0.365318 (rank : 53)	NC score	0.035939 (rank : 134)
Query Neighborhood Hits	96	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FBX43_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.112902 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

TRI68_MOUSE
θ value	0.62314 (rank : 55)	NC score	0.079513 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	356	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

FILA_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.017075 (rank : 143)
Query Neighborhood Hits	96	Target Neighborhood Hits	685	Shared Neighborhood Hits	6
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TRI16_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.054278 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	23
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI68_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.073518 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	267	Shared Neighborhood Hits	44
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

FBX5_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.089454 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

TRI42_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.074164 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BRE1B_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.022600 (rank : 142)
Query Neighborhood Hits	96	Target Neighborhood Hits	1040	Shared Neighborhood Hits	40
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

PEX10_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.104416 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	255	Shared Neighborhood Hits	45
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ZN364_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.033789 (rank : 135)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

BRE1B_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.022686 (rank : 141)
Query Neighborhood Hits	96	Target Neighborhood Hits	970	Shared Neighborhood Hits	39
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

TRIM6_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.072029 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

ZFP90_MOUSE
θ value	2.36792 (rank : 66)	NC score	-0.001663 (rank : 157)
Query Neighborhood Hits	96	Target Neighborhood Hits	748	Shared Neighborhood Hits	5
SwissProt Accessions	Q61967, Q3U4J5, Q543I6	Gene names	Zfp90, Nk10
Domain Architecture
Description	Zinc finger protein 90 (Zfp-90) (Zinc finger protein NK10).

PCD19_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.009045 (rank : 147)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TF3, Q8BL13	Gene names	Pcdh19, Kiaa1313
Domain Architecture	No domain graphic available
Description	Protocadherin-19 precursor.

RING2_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.061754 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	201	Shared Neighborhood Hits	34
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.061839 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	199	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN183_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.094490 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI50_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.069667 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	326	Shared Neighborhood Hits	44
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZN224_HUMAN
θ value	3.0926 (rank : 72)	NC score	-0.000133 (rank : 156)
Query Neighborhood Hits	96	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

CP2J5_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.004244 (rank : 153)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O54749	Gene names	Cyp2j5
Domain Architecture
Description	Cytochrome P450 2J5 (EC 1.14.14.1) (CYPIIJ5) (Arachidonic acid epoxygenase).

GP155_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.039400 (rank : 133)
Query Neighborhood Hits	96	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

SMC1A_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.001698 (rank : 155)
Query Neighborhood Hits	96	Target Neighborhood Hits	1384	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TRAF4_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.026953 (rank : 139)
Query Neighborhood Hits	96	Target Neighborhood Hits	338	Shared Neighborhood Hits	26
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRIM5_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.070153 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	424	Shared Neighborhood Hits	50
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

UBQL4_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.030728 (rank : 138)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

ZN364_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.025687 (rank : 140)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

BSN_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.012191 (rank : 145)
Query Neighborhood Hits	96	Target Neighborhood Hits	2057	Shared Neighborhood Hits	14
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PCD19_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.007975 (rank : 148)
Query Neighborhood Hits	96	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

RING1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.061849 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.061596 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RN183_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.091414 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.060839 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI59_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.085230 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.082866 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	292	Shared Neighborhood Hits	44
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

FGD4_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.006425 (rank : 150)
Query Neighborhood Hits	96	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

RN185_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.058861 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	211	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

ZFP90_HUMAN
θ value	6.88961 (rank : 90)	NC score	-0.002097 (rank : 158)
Query Neighborhood Hits	96	Target Neighborhood Hits	750	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TF47, Q49AD1, Q96MQ6	Gene names	ZFP90, KIAA1954
Domain Architecture	No domain graphic available
Description	Zinc finger protein 90 homolog (Zfp-90).

AF10_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.007386 (rank : 149)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

BBX_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.009955 (rank : 146)
Query Neighborhood Hits	96	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

K22O_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.003073 (rank : 154)
Query Neighborhood Hits	96	Target Neighborhood Hits	485	Shared Neighborhood Hits	7
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

MTMR5_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.004928 (rank : 151)
Query Neighborhood Hits	96	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MYSM1_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.012613 (rank : 144)
Query Neighborhood Hits	96	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

RIMS2_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.004688 (rank : 152)
Query Neighborhood Hits	96	Target Neighborhood Hits	376	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

CUL7_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.126166 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

PML_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.050667 (rank : 131)
Query Neighborhood Hits	96	Target Neighborhood Hits	248	Shared Neighborhood Hits	31
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.051578 (rank : 128)
Query Neighborhood Hits	96	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RN168_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.053006 (rank : 122)
Query Neighborhood Hits	96	Target Neighborhood Hits	370	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.054300 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	440	Shared Neighborhood Hits	42
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF4_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.057103 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	44
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.054574 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.059275 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.058724 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RO52_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.059794 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	419	Shared Neighborhood Hits	41
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

RO52_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.059937 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	360	Shared Neighborhood Hits	41
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TOPRS_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.054652 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	286	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.056303 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	263	Shared Neighborhood Hits	40
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI11_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.062746 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	316	Shared Neighborhood Hits	48
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.061067 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI12_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.064949 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	387	Shared Neighborhood Hits	46
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.071389 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	274	Shared Neighborhood Hits	43
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.069371 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI15_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.061269 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	395	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.057682 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	318	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI17_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.055176 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	620	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI25_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.055542 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	472	Shared Neighborhood Hits	44
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI26_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.066561 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	335	Shared Neighborhood Hits	39
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.067352 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	339	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI30_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.063089 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	434	Shared Neighborhood Hits	47
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI31_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.065745 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	299	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI34_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.058082 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	416	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.056414 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	332	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.065927 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	465	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.058302 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.060301 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	316	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI38_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.062710 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	373	Shared Neighborhood Hits	49
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI39_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.059287 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	693	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.059028 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	691	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI40_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.075327 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	279	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI41_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.055829 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	349	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI43_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.053262 (rank : 121)
Query Neighborhood Hits	96	Target Neighborhood Hits	341	Shared Neighborhood Hits	36
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI45_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.055289 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	155	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.050381 (rank : 132)
Query Neighborhood Hits	96	Target Neighborhood Hits	155	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI50_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.062487 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	294	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI52_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.056025 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.050741 (rank : 130)
Query Neighborhood Hits	96	Target Neighborhood Hits	209	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.052845 (rank : 124)
Query Neighborhood Hits	96	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.053880 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI60_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.058028 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	357	Shared Neighborhood Hits	40
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI60_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.054621 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	240	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.062753 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	584	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.065037 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	478	Shared Neighborhood Hits	44
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI63_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.051050 (rank : 129)
Query Neighborhood Hits	96	Target Neighborhood Hits	298	Shared Neighborhood Hits	29
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI65_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.060945 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	330	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.065320 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	340	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.062944 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.062576 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	249	Shared Neighborhood Hits	36
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM4_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.057218 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	321	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM6_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.065189 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	451	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM7_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.063112 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	336	Shared Neighborhood Hits	40
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.071391 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	358	Shared Neighborhood Hits	44
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM8_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.052889 (rank : 123)
Query Neighborhood Hits	96	Target Neighborhood Hits	650	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.053583 (rank : 120)
Query Neighborhood Hits	96	Target Neighborhood Hits	674	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM9_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.052276 (rank : 126)
Query Neighborhood Hits	96	Target Neighborhood Hits	294	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.051755 (rank : 127)
Query Neighborhood Hits	96	Target Neighborhood Hits	274	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

ZN179_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.052418 (rank : 125)
Query Neighborhood Hits	96	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

Hits sorted by NC score

RNF19_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.996949 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

IBRD3_HUMAN
NC score	0.979497 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

UB7I4_MOUSE
NC score	0.747369 (rank : 4)	θ value	1.86321e-21 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
NC score	0.746049 (rank : 5)	θ value	9.24701e-21 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD2_HUMAN
NC score	0.732938 (rank : 6)	θ value	9.24701e-21 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD2_MOUSE
NC score	0.718963 (rank : 7)	θ value	1.38178e-16 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

ARI1_HUMAN
NC score	0.716923 (rank : 8)	θ value	1.2077e-20 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.716784 (rank : 9)	θ value	1.2077e-20 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

ARI2_HUMAN
NC score	0.697484 (rank : 10)	θ value	4.74913e-17 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.695378 (rank : 11)	θ value	1.058e-16 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

RNF14_HUMAN
NC score	0.677783 (rank : 12)	θ value	8.38298e-14 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
NC score	0.677243 (rank : 13)	θ value	1.86753e-13 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

IBRD1_HUMAN
NC score	0.617534 (rank : 14)	θ value	4.92598e-06 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

UB7I3_MOUSE
NC score	0.544621 (rank : 15)	θ value	5.26297e-08 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

PRKN2_MOUSE
NC score	0.540854 (rank : 16)	θ value	6.21693e-09 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PARC_HUMAN
NC score	0.537188 (rank : 17)	θ value	8.95645e-16 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

UB7I3_HUMAN
NC score	0.534639 (rank : 18)	θ value	5.81887e-07 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

PRKN2_HUMAN
NC score	0.528703 (rank : 19)	θ value	1.99992e-07 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PARC_MOUSE
NC score	0.522893 (rank : 20)	θ value	4.91457e-14 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	114	Shared Neighborhood Hits	33
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

RNF31_MOUSE
NC score	0.515025 (rank : 21)	θ value	9.59137e-10 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

RNF31_HUMAN
NC score	0.512065 (rank : 22)	θ value	2.79066e-09 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	110	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UB7I1_HUMAN
NC score	0.508547 (rank : 23)	θ value	1.63604e-09 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
NC score	0.503589 (rank : 24)	θ value	3.64472e-09 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

RN152_MOUSE
NC score	0.161397 (rank : 25)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN152_HUMAN
NC score	0.160989 (rank : 26)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

MKRN3_MOUSE
NC score	0.145662 (rank : 27)	θ value	0.0563607 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MKRN4_HUMAN
NC score	0.144152 (rank : 28)	θ value	0.0330416 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MKRN1_MOUSE
NC score	0.140379 (rank : 29)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN1_HUMAN
NC score	0.140249 (rank : 30)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN3_HUMAN
NC score	0.140131 (rank : 31)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	165	Shared Neighborhood Hits	31
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

TRI32_HUMAN
NC score	0.130572 (rank : 32)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRIM3_HUMAN
NC score	0.129590 (rank : 33)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	357	Shared Neighborhood Hits	50
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

MKRN2_HUMAN
NC score	0.127614 (rank : 34)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

TRI32_MOUSE
NC score	0.127608 (rank : 35)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

CUL7_HUMAN
NC score	0.126166 (rank : 36)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

MKRN2_MOUSE
NC score	0.125692 (rank : 37)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	130	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

TRIM3_MOUSE
NC score	0.121690 (rank : 38)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	351	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI10_MOUSE
NC score	0.120292 (rank : 39)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	285	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRIM2_HUMAN
NC score	0.119546 (rank : 40)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	330	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.118860 (rank : 41)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	331	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

FBX43_HUMAN
NC score	0.112945 (rank : 42)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX43_MOUSE
NC score	0.112902 (rank : 43)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

TRI56_MOUSE
NC score	0.108182 (rank : 44)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.105532 (rank : 45)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

PEX10_HUMAN
NC score	0.104416 (rank : 46)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	255	Shared Neighborhood Hits	45
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRI10_HUMAN
NC score	0.102779 (rank : 47)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	315	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI22_HUMAN
NC score	0.097151 (rank : 48)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

RN183_MOUSE
NC score	0.094490 (rank : 49)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

ZCH13_HUMAN
NC score	0.091461 (rank : 50)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WW36	Gene names	ZCCHC13
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 13.

RN183_HUMAN
NC score	0.091414 (rank : 51)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI42_MOUSE
NC score	0.089727 (rank : 52)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	316	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

FBX5_HUMAN
NC score	0.089454 (rank : 53)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

TRI35_HUMAN
NC score	0.086492 (rank : 54)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	382	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI59_HUMAN
NC score	0.085230 (rank : 55)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
NC score	0.082866 (rank : 56)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	292	Shared Neighborhood Hits	44
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI68_MOUSE
NC score	0.079513 (rank : 57)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	356	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI27_HUMAN
NC score	0.077281 (rank : 58)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	273	Shared Neighborhood Hits	40
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI40_HUMAN
NC score	0.075327 (rank : 59)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	96	Target Neighborhood Hits	279	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI27_MOUSE
NC score	0.074733 (rank : 60)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	261	Shared Neighborhood Hits	36
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI42_HUMAN
NC score	0.074164 (rank : 61)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI68_HUMAN
NC score	0.073518 (rank : 62)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	267	Shared Neighborhood Hits	44
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRIM6_HUMAN
NC score	0.072029 (rank : 63)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM7_MOUSE
NC score	0.071391 (rank : 64)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	96	Target Neighborhood Hits	358	Shared Neighborhood Hits	44
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI13_HUMAN
NC score	0.071389 (rank : 65)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	274	Shared Neighborhood Hits	43
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRIM5_HUMAN
NC score	0.070153 (rank : 66)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	424	Shared Neighborhood Hits	50
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI50_MOUSE
NC score	0.069667 (rank : 67)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	326	Shared Neighborhood Hits	44
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI13_MOUSE
NC score	0.069371 (rank : 68)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI26_MOUSE
NC score	0.067352 (rank : 69)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	96	Target Neighborhood Hits	339	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
NC score	0.066561 (rank : 70)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	335	Shared Neighborhood Hits	39
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI35_MOUSE
NC score	0.065927 (rank : 71)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	96	Target Neighborhood Hits	465	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI31_HUMAN
NC score	0.065745 (rank : 72)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	96	Target Neighborhood Hits	299	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI65_MOUSE
NC score	0.065320 (rank : 73)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	96	Target Neighborhood Hits	340	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM6_MOUSE
NC score	0.065189 (rank : 74)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	96	Target Neighborhood Hits	451	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI62_MOUSE
NC score	0.065037 (rank : 75)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	96	Target Neighborhood Hits	478	Shared Neighborhood Hits	44
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI12_MOUSE
NC score	0.064949 (rank : 76)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	387	Shared Neighborhood Hits	46
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM7_HUMAN
NC score	0.063112 (rank : 77)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	96	Target Neighborhood Hits	336	Shared Neighborhood Hits	40
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI30_MOUSE
NC score	0.063089 (rank : 78)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	96	Target Neighborhood Hits	434	Shared Neighborhood Hits	47
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI73_HUMAN
NC score	0.062944 (rank : 79)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	96	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI62_HUMAN
NC score	0.062753 (rank : 80)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	96	Target Neighborhood Hits	584	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI11_HUMAN
NC score	0.062746 (rank : 81)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	316	Shared Neighborhood Hits	48
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI38_HUMAN
NC score	0.062710 (rank : 82)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	96	Target Neighborhood Hits	373	Shared Neighborhood Hits	49
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI74_HUMAN
NC score	0.062576 (rank : 83)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	96	Target Neighborhood Hits	249	Shared Neighborhood Hits	36
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI50_HUMAN
NC score	0.062487 (rank : 84)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	96	Target Neighborhood Hits	294	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RING1_HUMAN
NC score	0.061849 (rank : 85)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING2_MOUSE
NC score	0.061839 (rank : 86)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	199	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.061754 (rank : 87)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	201	Shared Neighborhood Hits	34
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING1_MOUSE
NC score	0.061596 (rank : 88)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI15_HUMAN
NC score	0.061269 (rank : 89)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	395	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI11_MOUSE
NC score	0.061067 (rank : 90)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI65_HUMAN
NC score	0.060945 (rank : 91)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	96	Target Neighborhood Hits	330	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RN185_HUMAN
NC score	0.060839 (rank : 92)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI37_MOUSE
NC score	0.060301 (rank : 93)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	96	Target Neighborhood Hits	316	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

RO52_MOUSE
NC score	0.059937 (rank : 94)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	360	Shared Neighborhood Hits	41
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RO52_HUMAN
NC score	0.059794 (rank : 95)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	419	Shared Neighborhood Hits	41
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI39_HUMAN
NC score	0.059287 (rank : 96)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	96	Target Neighborhood Hits	693	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RNF5_HUMAN
NC score	0.059275 (rank : 97)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI39_MOUSE
NC score	0.059028 (rank : 98)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	96	Target Neighborhood Hits	691	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RN185_MOUSE
NC score	0.058861 (rank : 99)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	211	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF5_MOUSE
NC score	0.058724 (rank : 100)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI37_HUMAN
NC score	0.058302 (rank : 101)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	96	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI34_HUMAN
NC score	0.058082 (rank : 102)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	96	Target Neighborhood Hits	416	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI60_HUMAN
NC score	0.058028 (rank : 103)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	96	Target Neighborhood Hits	357	Shared Neighborhood Hits	40
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI17_HUMAN
NC score	0.057682 (rank : 104)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	318	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM4_HUMAN
NC score	0.057218 (rank : 105)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	96	Target Neighborhood Hits	321	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

RNF4_HUMAN
NC score	0.057103 (rank : 106)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	44
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI34_MOUSE
NC score	0.056414 (rank : 107)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	96	Target Neighborhood Hits	332	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TOPRS_MOUSE
NC score	0.056303 (rank : 108)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	263	Shared Neighborhood Hits	40
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI52_HUMAN
NC score	0.056025 (rank : 109)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI41_HUMAN
NC score	0.055829 (rank : 110)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	96	Target Neighborhood Hits	349	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI25_HUMAN
NC score	0.055542 (rank : 111)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	472	Shared Neighborhood Hits	44
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI45_HUMAN
NC score	0.055289 (rank : 112)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	96	Target Neighborhood Hits	155	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI17_MOUSE
NC score	0.055176 (rank : 113)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	620	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TOPRS_HUMAN
NC score	0.054652 (rank : 114)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	286	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI60_MOUSE
NC score	0.054621 (rank : 115)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	96	Target Neighborhood Hits	240	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

RNF4_MOUSE
NC score	0.054574 (rank : 116)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RN168_MOUSE
NC score	0.054300 (rank : 117)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	440	Shared Neighborhood Hits	42
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI16_HUMAN
NC score	0.054278 (rank : 118)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	23
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI55_HUMAN
NC score	0.053880 (rank : 119)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	96	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM8_MOUSE
NC score	0.053583 (rank : 120)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	96	Target Neighborhood Hits	674	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI43_HUMAN
NC score	0.053262 (rank : 121)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	96	Target Neighborhood Hits	341	Shared Neighborhood Hits	36
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RN168_HUMAN
NC score	0.053006 (rank : 122)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	370	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRIM8_HUMAN
NC score	0.052889 (rank : 123)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	96	Target Neighborhood Hits	650	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI54_MOUSE
NC score	0.052845 (rank : 124)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	96	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

ZN179_HUMAN
NC score	0.052418 (rank : 125)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	96	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRIM9_HUMAN
NC score	0.052276 (rank : 126)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	96	Target Neighborhood Hits	294	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.051755 (rank : 127)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	96	Target Neighborhood Hits	274	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

PML_MOUSE
NC score	0.051578 (rank : 128)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI63_HUMAN
NC score	0.051050 (rank : 129)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	96	Target Neighborhood Hits	298	Shared Neighborhood Hits	29
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI54_HUMAN
NC score	0.050741 (rank : 130)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	96	Target Neighborhood Hits	209	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

PML_HUMAN
NC score	0.050667 (rank : 131)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	248	Shared Neighborhood Hits	31
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI45_MOUSE
NC score	0.050381 (rank : 132)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	96	Target Neighborhood Hits	155	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

GP155_HUMAN
NC score	0.039400 (rank : 133)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

FRAS1_MOUSE
NC score	0.035939 (rank : 134)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ZN364_MOUSE
NC score	0.033789 (rank : 135)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

FRAS1_HUMAN
NC score	0.032366 (rank : 136)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	759	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PGCA_MOUSE
NC score	0.031171 (rank : 137)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	643	Shared Neighborhood Hits	5
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

UBQL4_HUMAN
NC score	0.030728 (rank : 138)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

TRAF4_MOUSE
NC score	0.026953 (rank : 139)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	338	Shared Neighborhood Hits	26
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

ZN364_HUMAN
NC score	0.025687 (rank : 140)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

BRE1B_MOUSE
NC score	0.022686 (rank : 141)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	970	Shared Neighborhood Hits	39
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.022600 (rank : 142)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	1040	Shared Neighborhood Hits	40
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

FILA_HUMAN
NC score	0.017075 (rank : 143)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	685	Shared Neighborhood Hits	6
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MYSM1_HUMAN
NC score	0.012613 (rank : 144)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

BSN_MOUSE
NC score	0.012191 (rank : 145)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	2057	Shared Neighborhood Hits	14
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BBX_MOUSE
NC score	0.009955 (rank : 146)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

PCD19_MOUSE
NC score	0.009045 (rank : 147)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TF3, Q8BL13	Gene names	Pcdh19, Kiaa1313
Domain Architecture	No domain graphic available
Description	Protocadherin-19 precursor.

PCD19_HUMAN
NC score	0.007975 (rank : 148)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

AF10_HUMAN
NC score	0.007386 (rank : 149)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

FGD4_MOUSE
NC score	0.006425 (rank : 150)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

MTMR5_HUMAN
NC score	0.004928 (rank : 151)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

RIMS2_MOUSE
NC score	0.004688 (rank : 152)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	376	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

CP2J5_MOUSE
NC score	0.004244 (rank : 153)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O54749	Gene names	Cyp2j5
Domain Architecture
Description	Cytochrome P450 2J5 (EC 1.14.14.1) (CYPIIJ5) (Arachidonic acid epoxygenase).

K22O_HUMAN
NC score	0.003073 (rank : 154)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	485	Shared Neighborhood Hits	7
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

SMC1A_MOUSE
NC score	0.001698 (rank : 155)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	1384	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

ZN224_HUMAN
NC score	-0.000133 (rank : 156)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZFP90_MOUSE
NC score	-0.001663 (rank : 157)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	748	Shared Neighborhood Hits	5
SwissProt Accessions	Q61967, Q3U4J5, Q543I6	Gene names	Zfp90, Nk10
Domain Architecture
Description	Zinc finger protein 90 (Zfp-90) (Zinc finger protein NK10).

ZFP90_HUMAN
NC score	-0.002097 (rank : 158)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	750	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TF47, Q49AD1, Q96MQ6	Gene names	ZFP90, KIAA1954
Domain Architecture	No domain graphic available
Description	Zinc finger protein 90 homolog (Zfp-90).