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Network neighborhood for query Sequence : TRIM3_HUMAN

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TRIM3_HUMAN
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRIM2_HUMAN
θ value	0 (rank : 1)	NC score	0.973426 (rank : 4)
Query Neighborhood Hits	357	Target Neighborhood Hits	330	Shared Neighborhood Hits	254
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0 (rank : 2)	NC score	0.973521 (rank : 3)
Query Neighborhood Hits	357	Target Neighborhood Hits	331	Shared Neighborhood Hits	253
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	357	Target Neighborhood Hits	357	Shared Neighborhood Hits	357
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	0 (rank : 4)	NC score	0.997098 (rank : 2)
Query Neighborhood Hits	357	Target Neighborhood Hits	351	Shared Neighborhood Hits	337
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI45_HUMAN
θ value	1.42001e-37 (rank : 5)	NC score	0.734423 (rank : 11)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	5.96599e-36 (rank : 6)	NC score	0.721514 (rank : 14)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	112
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI56_HUMAN
θ value	5.0505e-35 (rank : 7)	NC score	0.772793 (rank : 6)
Query Neighborhood Hits	357	Target Neighborhood Hits	339	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	7.80994e-28 (rank : 8)	NC score	0.785838 (rank : 5)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	184
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI54_MOUSE
θ value	2.20094e-22 (rank : 9)	NC score	0.729661 (rank : 12)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	158
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_HUMAN
θ value	6.40375e-22 (rank : 10)	NC score	0.728355 (rank : 13)
Query Neighborhood Hits	357	Target Neighborhood Hits	209	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TIF1G_MOUSE
θ value	4.29542e-18 (rank : 11)	NC score	0.548697 (rank : 86)
Query Neighborhood Hits	357	Target Neighborhood Hits	498	Shared Neighborhood Hits	134
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
θ value	5.60996e-18 (rank : 12)	NC score	0.555681 (rank : 83)
Query Neighborhood Hits	357	Target Neighborhood Hits	410	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI63_HUMAN
θ value	7.32683e-18 (rank : 13)	NC score	0.720363 (rank : 15)
Query Neighborhood Hits	357	Target Neighborhood Hits	298	Shared Neighborhood Hits	171
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI59_HUMAN
θ value	1.63225e-17 (rank : 14)	NC score	0.746267 (rank : 7)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	201
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI55_HUMAN
θ value	4.74913e-17 (rank : 15)	NC score	0.708163 (rank : 17)
Query Neighborhood Hits	357	Target Neighborhood Hits	292	Shared Neighborhood Hits	168
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI65_HUMAN
θ value	8.10077e-17 (rank : 16)	NC score	0.694427 (rank : 20)
Query Neighborhood Hits	357	Target Neighborhood Hits	330	Shared Neighborhood Hits	229
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TIF1A_HUMAN
θ value	5.25075e-16 (rank : 17)	NC score	0.476498 (rank : 102)
Query Neighborhood Hits	357	Target Neighborhood Hits	327	Shared Neighborhood Hits	121
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI65_MOUSE
θ value	6.85773e-16 (rank : 18)	NC score	0.670099 (rank : 22)
Query Neighborhood Hits	357	Target Neighborhood Hits	340	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI39_HUMAN
θ value	8.95645e-16 (rank : 19)	NC score	0.596892 (rank : 50)
Query Neighborhood Hits	357	Target Neighborhood Hits	693	Shared Neighborhood Hits	254
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI63_MOUSE
θ value	8.95645e-16 (rank : 20)	NC score	0.716987 (rank : 16)
Query Neighborhood Hits	357	Target Neighborhood Hits	240	Shared Neighborhood Hits	169
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TIF1A_MOUSE
θ value	1.99529e-15 (rank : 21)	NC score	0.450158 (rank : 108)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	108
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI59_MOUSE
θ value	1.99529e-15 (rank : 22)	NC score	0.742172 (rank : 8)
Query Neighborhood Hits	357	Target Neighborhood Hits	292	Shared Neighborhood Hits	207
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI10_MOUSE
θ value	3.40345e-15 (rank : 23)	NC score	0.614846 (rank : 37)
Query Neighborhood Hits	357	Target Neighborhood Hits	285	Shared Neighborhood Hits	200
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI13_HUMAN
θ value	3.40345e-15 (rank : 24)	NC score	0.738080 (rank : 10)
Query Neighborhood Hits	357	Target Neighborhood Hits	274	Shared Neighborhood Hits	212
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI39_MOUSE
θ value	4.44505e-15 (rank : 25)	NC score	0.594663 (rank : 53)
Query Neighborhood Hits	357	Target Neighborhood Hits	691	Shared Neighborhood Hits	257
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI13_MOUSE
θ value	1.29331e-14 (rank : 26)	NC score	0.738849 (rank : 9)
Query Neighborhood Hits	357	Target Neighborhood Hits	282	Shared Neighborhood Hits	219
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TIF1B_HUMAN
θ value	2.88119e-14 (rank : 27)	NC score	0.557388 (rank : 81)
Query Neighborhood Hits	357	Target Neighborhood Hits	312	Shared Neighborhood Hits	123
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI62_MOUSE
θ value	4.91457e-14 (rank : 28)	NC score	0.601689 (rank : 45)
Query Neighborhood Hits	357	Target Neighborhood Hits	478	Shared Neighborhood Hits	212
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TIF1B_MOUSE
θ value	8.38298e-14 (rank : 29)	NC score	0.550628 (rank : 85)
Query Neighborhood Hits	357	Target Neighborhood Hits	276	Shared Neighborhood Hits	122
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRIM7_MOUSE
θ value	1.09485e-13 (rank : 30)	NC score	0.600659 (rank : 46)
Query Neighborhood Hits	357	Target Neighborhood Hits	358	Shared Neighborhood Hits	207
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI62_HUMAN
θ value	1.42992e-13 (rank : 31)	NC score	0.599440 (rank : 48)
Query Neighborhood Hits	357	Target Neighborhood Hits	584	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

ARD1_HUMAN
θ value	5.43371e-13 (rank : 32)	NC score	0.277436 (rank : 179)
Query Neighborhood Hits	357	Target Neighborhood Hits	621	Shared Neighborhood Hits	89
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

TRI11_HUMAN
θ value	5.43371e-13 (rank : 33)	NC score	0.567852 (rank : 72)
Query Neighborhood Hits	357	Target Neighborhood Hits	316	Shared Neighborhood Hits	207
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI36_MOUSE
θ value	5.43371e-13 (rank : 34)	NC score	0.614720 (rank : 38)
Query Neighborhood Hits	357	Target Neighborhood Hits	266	Shared Neighborhood Hits	162
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI32_HUMAN
θ value	7.09661e-13 (rank : 35)	NC score	0.702202 (rank : 18)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	183
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI36_HUMAN
θ value	2.0648e-12 (rank : 36)	NC score	0.621018 (rank : 35)
Query Neighborhood Hits	357	Target Neighborhood Hits	282	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM7_HUMAN
θ value	2.0648e-12 (rank : 37)	NC score	0.586304 (rank : 55)
Query Neighborhood Hits	357	Target Neighborhood Hits	336	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

RO52_HUMAN
θ value	4.59992e-12 (rank : 38)	NC score	0.574304 (rank : 68)
Query Neighborhood Hits	357	Target Neighborhood Hits	419	Shared Neighborhood Hits	231
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI32_MOUSE
θ value	4.59992e-12 (rank : 39)	NC score	0.696179 (rank : 19)
Query Neighborhood Hits	357	Target Neighborhood Hits	271	Shared Neighborhood Hits	184
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI31_HUMAN
θ value	1.02475e-11 (rank : 40)	NC score	0.681199 (rank : 21)
Query Neighborhood Hits	357	Target Neighborhood Hits	299	Shared Neighborhood Hits	208
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

ARD1_MOUSE
θ value	1.74796e-11 (rank : 41)	NC score	0.284500 (rank : 173)
Query Neighborhood Hits	357	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRI26_MOUSE
θ value	2.98157e-11 (rank : 42)	NC score	0.612957 (rank : 39)
Query Neighborhood Hits	357	Target Neighborhood Hits	339	Shared Neighborhood Hits	210
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_MOUSE
θ value	2.98157e-11 (rank : 43)	NC score	0.571164 (rank : 70)
Query Neighborhood Hits	357	Target Neighborhood Hits	261	Shared Neighborhood Hits	187
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI35_MOUSE
θ value	2.98157e-11 (rank : 44)	NC score	0.632833 (rank : 32)
Query Neighborhood Hits	357	Target Neighborhood Hits	465	Shared Neighborhood Hits	227
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRIM1_MOUSE
θ value	2.98157e-11 (rank : 45)	NC score	0.637479 (rank : 30)
Query Neighborhood Hits	357	Target Neighborhood Hits	361	Shared Neighborhood Hits	200
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM5_HUMAN
θ value	2.98157e-11 (rank : 46)	NC score	0.597861 (rank : 49)
Query Neighborhood Hits	357	Target Neighborhood Hits	424	Shared Neighborhood Hits	213
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI12_MOUSE
θ value	5.08577e-11 (rank : 47)	NC score	0.639934 (rank : 27)
Query Neighborhood Hits	357	Target Neighborhood Hits	387	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI27_HUMAN
θ value	5.08577e-11 (rank : 48)	NC score	0.573800 (rank : 69)
Query Neighborhood Hits	357	Target Neighborhood Hits	273	Shared Neighborhood Hits	192
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRIM1_HUMAN
θ value	5.08577e-11 (rank : 49)	NC score	0.639600 (rank : 28)
Query Neighborhood Hits	357	Target Neighborhood Hits	345	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI18_MOUSE
θ value	1.47974e-10 (rank : 50)	NC score	0.637559 (rank : 29)
Query Neighborhood Hits	357	Target Neighborhood Hits	292	Shared Neighborhood Hits	189
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI10_HUMAN
θ value	2.52405e-10 (rank : 51)	NC score	0.611017 (rank : 40)
Query Neighborhood Hits	357	Target Neighborhood Hits	315	Shared Neighborhood Hits	209
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI26_HUMAN
θ value	3.29651e-10 (rank : 52)	NC score	0.615563 (rank : 36)
Query Neighborhood Hits	357	Target Neighborhood Hits	335	Shared Neighborhood Hits	208
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRIM6_MOUSE
θ value	3.29651e-10 (rank : 53)	NC score	0.582774 (rank : 57)
Query Neighborhood Hits	357	Target Neighborhood Hits	451	Shared Neighborhood Hits	212
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI50_MOUSE
θ value	4.30538e-10 (rank : 54)	NC score	0.625123 (rank : 33)
Query Neighborhood Hits	357	Target Neighborhood Hits	326	Shared Neighborhood Hits	219
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

PML_HUMAN
θ value	7.34386e-10 (rank : 55)	NC score	0.548653 (rank : 87)
Query Neighborhood Hits	357	Target Neighborhood Hits	248	Shared Neighborhood Hits	122
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI17_HUMAN
θ value	7.34386e-10 (rank : 56)	NC score	0.579531 (rank : 62)
Query Neighborhood Hits	357	Target Neighborhood Hits	318	Shared Neighborhood Hits	198
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI18_HUMAN
θ value	7.34386e-10 (rank : 57)	NC score	0.634258 (rank : 31)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	189
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI50_HUMAN
θ value	7.34386e-10 (rank : 58)	NC score	0.623942 (rank : 34)
Query Neighborhood Hits	357	Target Neighborhood Hits	294	Shared Neighborhood Hits	212
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM6_HUMAN
θ value	9.59137e-10 (rank : 59)	NC score	0.580431 (rank : 60)
Query Neighborhood Hits	357	Target Neighborhood Hits	412	Shared Neighborhood Hits	210
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI37_HUMAN
θ value	1.25267e-09 (rank : 60)	NC score	0.603207 (rank : 42)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	171
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	1.25267e-09 (rank : 61)	NC score	0.602806 (rank : 43)
Query Neighborhood Hits	357	Target Neighborhood Hits	316	Shared Neighborhood Hits	170
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

NHLC1_MOUSE
θ value	1.63604e-09 (rank : 62)	NC score	0.429276 (rank : 114)
Query Neighborhood Hits	357	Target Neighborhood Hits	103	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RO52_MOUSE
θ value	1.63604e-09 (rank : 63)	NC score	0.562401 (rank : 79)
Query Neighborhood Hits	357	Target Neighborhood Hits	360	Shared Neighborhood Hits	204
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI11_MOUSE
θ value	1.63604e-09 (rank : 64)	NC score	0.563385 (rank : 78)
Query Neighborhood Hits	357	Target Neighborhood Hits	329	Shared Neighborhood Hits	213
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

NHLC1_HUMAN
θ value	2.13673e-09 (rank : 65)	NC score	0.407607 (rank : 121)
Query Neighborhood Hits	357	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRI38_HUMAN
θ value	2.13673e-09 (rank : 66)	NC score	0.561622 (rank : 80)
Query Neighborhood Hits	357	Target Neighborhood Hits	373	Shared Neighborhood Hits	204
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

PML_MOUSE
θ value	4.76016e-09 (rank : 67)	NC score	0.539250 (rank : 89)
Query Neighborhood Hits	357	Target Neighborhood Hits	246	Shared Neighborhood Hits	128
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI22_HUMAN
θ value	4.76016e-09 (rank : 68)	NC score	0.595269 (rank : 52)
Query Neighborhood Hits	357	Target Neighborhood Hits	396	Shared Neighborhood Hits	216
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI35_HUMAN
θ value	6.21693e-09 (rank : 69)	NC score	0.610894 (rank : 41)
Query Neighborhood Hits	357	Target Neighborhood Hits	382	Shared Neighborhood Hits	214
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI15_HUMAN
θ value	8.11959e-09 (rank : 70)	NC score	0.566023 (rank : 75)
Query Neighborhood Hits	357	Target Neighborhood Hits	395	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
θ value	1.06045e-08 (rank : 71)	NC score	0.578948 (rank : 63)
Query Neighborhood Hits	357	Target Neighborhood Hits	620	Shared Neighborhood Hits	224
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

FLNC_HUMAN
θ value	1.38499e-08 (rank : 72)	NC score	0.167837 (rank : 233)
Query Neighborhood Hits	357	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

TRI60_HUMAN
θ value	1.80886e-08 (rank : 73)	NC score	0.578336 (rank : 64)
Query Neighborhood Hits	357	Target Neighborhood Hits	357	Shared Neighborhood Hits	209
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI30_MOUSE
θ value	2.36244e-08 (rank : 74)	NC score	0.602733 (rank : 44)
Query Neighborhood Hits	357	Target Neighborhood Hits	434	Shared Neighborhood Hits	211
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRIM9_HUMAN
θ value	3.08544e-08 (rank : 75)	NC score	0.582412 (rank : 59)
Query Neighborhood Hits	357	Target Neighborhood Hits	294	Shared Neighborhood Hits	156
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

AMD_HUMAN
θ value	4.0297e-08 (rank : 76)	NC score	0.213956 (rank : 211)
Query Neighborhood Hits	357	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	P19021, O95080, Q16252, Q16253, Q86U53, Q8WVC7, Q9UCG0	Gene names	PAM
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

TRI41_HUMAN
θ value	4.0297e-08 (rank : 77)	NC score	0.564424 (rank : 76)
Query Neighborhood Hits	357	Target Neighborhood Hits	349	Shared Neighborhood Hits	187
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI34_HUMAN
θ value	5.26297e-08 (rank : 78)	NC score	0.575338 (rank : 66)
Query Neighborhood Hits	357	Target Neighborhood Hits	416	Shared Neighborhood Hits	187
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI60_MOUSE
θ value	5.26297e-08 (rank : 79)	NC score	0.555280 (rank : 84)
Query Neighborhood Hits	357	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM9_MOUSE
θ value	5.26297e-08 (rank : 80)	NC score	0.576661 (rank : 65)
Query Neighborhood Hits	357	Target Neighborhood Hits	274	Shared Neighborhood Hits	156
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRIM4_HUMAN
θ value	1.53129e-07 (rank : 81)	NC score	0.596046 (rank : 51)
Query Neighborhood Hits	357	Target Neighborhood Hits	321	Shared Neighborhood Hits	203
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI29_MOUSE
θ value	4.45536e-07 (rank : 82)	NC score	0.503989 (rank : 90)
Query Neighborhood Hits	357	Target Neighborhood Hits	306	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI68_MOUSE
θ value	5.81887e-07 (rank : 83)	NC score	0.567420 (rank : 74)
Query Neighborhood Hits	357	Target Neighborhood Hits	356	Shared Neighborhood Hits	212
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRIM8_MOUSE
θ value	7.59969e-07 (rank : 84)	NC score	0.642718 (rank : 25)
Query Neighborhood Hits	357	Target Neighborhood Hits	674	Shared Neighborhood Hits	222
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI66_MOUSE
θ value	9.92553e-07 (rank : 85)	NC score	0.334866 (rank : 149)
Query Neighborhood Hits	357	Target Neighborhood Hits	491	Shared Neighborhood Hits	81
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI74_HUMAN
θ value	9.92553e-07 (rank : 86)	NC score	0.664307 (rank : 23)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	199
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

FLNA_HUMAN
θ value	1.29631e-06 (rank : 87)	NC score	0.164896 (rank : 236)
Query Neighborhood Hits	357	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
θ value	1.29631e-06 (rank : 88)	NC score	0.164963 (rank : 235)
Query Neighborhood Hits	357	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

TRI66_HUMAN
θ value	1.29631e-06 (rank : 89)	NC score	0.330969 (rank : 152)
Query Neighborhood Hits	357	Target Neighborhood Hits	479	Shared Neighborhood Hits	76
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI68_HUMAN
θ value	1.29631e-06 (rank : 90)	NC score	0.557143 (rank : 82)
Query Neighborhood Hits	357	Target Neighborhood Hits	267	Shared Neighborhood Hits	189
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI73_HUMAN
θ value	1.69304e-06 (rank : 91)	NC score	0.663755 (rank : 24)
Query Neighborhood Hits	357	Target Neighborhood Hits	258	Shared Neighborhood Hits	204
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

FLNB_HUMAN
θ value	2.21117e-06 (rank : 92)	NC score	0.161325 (rank : 239)
Query Neighborhood Hits	357	Target Neighborhood Hits	111	Shared Neighborhood Hits	15
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

TRI47_HUMAN
θ value	2.21117e-06 (rank : 93)	NC score	0.568933 (rank : 71)
Query Neighborhood Hits	357	Target Neighborhood Hits	286	Shared Neighborhood Hits	186
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

FLNB_MOUSE
θ value	2.88788e-06 (rank : 94)	NC score	0.161259 (rank : 240)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

TRI29_HUMAN
θ value	2.88788e-06 (rank : 95)	NC score	0.492957 (rank : 95)
Query Neighborhood Hits	357	Target Neighborhood Hits	273	Shared Neighborhood Hits	112
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI25_HUMAN
θ value	3.77169e-06 (rank : 96)	NC score	0.580404 (rank : 61)
Query Neighborhood Hits	357	Target Neighborhood Hits	472	Shared Neighborhood Hits	224
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI40_HUMAN
θ value	3.77169e-06 (rank : 97)	NC score	0.600269 (rank : 47)
Query Neighborhood Hits	357	Target Neighborhood Hits	279	Shared Neighborhood Hits	187
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM8_HUMAN
θ value	3.77169e-06 (rank : 98)	NC score	0.640372 (rank : 26)
Query Neighborhood Hits	357	Target Neighborhood Hits	650	Shared Neighborhood Hits	224
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CHFR_MOUSE
θ value	6.43352e-06 (rank : 99)	NC score	0.421986 (rank : 118)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI25_MOUSE
θ value	6.43352e-06 (rank : 100)	NC score	0.593764 (rank : 54)
Query Neighborhood Hits	357	Target Neighborhood Hits	446	Shared Neighborhood Hits	221
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI34_MOUSE
θ value	1.09739e-05 (rank : 101)	NC score	0.543384 (rank : 88)
Query Neighborhood Hits	357	Target Neighborhood Hits	332	Shared Neighborhood Hits	166
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

CHFR_HUMAN
θ value	1.43324e-05 (rank : 102)	NC score	0.424793 (rank : 116)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	181
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI43_HUMAN
θ value	7.1131e-05 (rank : 103)	NC score	0.567706 (rank : 73)
Query Neighborhood Hits	357	Target Neighborhood Hits	341	Shared Neighborhood Hits	202
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI46_MOUSE
θ value	9.29e-05 (rank : 104)	NC score	0.583832 (rank : 56)
Query Neighborhood Hits	357	Target Neighborhood Hits	287	Shared Neighborhood Hits	177
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ZN313_MOUSE
θ value	9.29e-05 (rank : 105)	NC score	0.497651 (rank : 92)
Query Neighborhood Hits	357	Target Neighborhood Hits	273	Shared Neighborhood Hits	186
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RN152_HUMAN
θ value	0.000158464 (rank : 106)	NC score	0.374325 (rank : 132)
Query Neighborhood Hits	357	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

ZN313_HUMAN
θ value	0.000158464 (rank : 107)	NC score	0.488998 (rank : 98)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

AMD_MOUSE
θ value	0.00020696 (rank : 108)	NC score	0.188588 (rank : 221)
Query Neighborhood Hits	357	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P97467	Gene names	Pam
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

RN152_MOUSE
θ value	0.00020696 (rank : 109)	NC score	0.377817 (rank : 129)
Query Neighborhood Hits	357	Target Neighborhood Hits	109	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

LNX2_MOUSE
θ value	0.000270298 (rank : 110)	NC score	0.256548 (rank : 189)
Query Neighborhood Hits	357	Target Neighborhood Hits	407	Shared Neighborhood Hits	176
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TRI16_MOUSE
θ value	0.000270298 (rank : 111)	NC score	0.456651 (rank : 107)
Query Neighborhood Hits	357	Target Neighborhood Hits	196	Shared Neighborhood Hits	98
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

RNF13_HUMAN
θ value	0.00035302 (rank : 112)	NC score	0.211776 (rank : 213)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

LNX2_HUMAN
θ value	0.000461057 (rank : 113)	NC score	0.257483 (rank : 188)
Query Neighborhood Hits	357	Target Neighborhood Hits	389	Shared Neighborhood Hits	176
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RN167_HUMAN
θ value	0.000461057 (rank : 114)	NC score	0.220605 (rank : 206)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TRI42_MOUSE
θ value	0.000461057 (rank : 115)	NC score	0.495667 (rank : 93)
Query Neighborhood Hits	357	Target Neighborhood Hits	316	Shared Neighborhood Hits	129
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI46_HUMAN
θ value	0.000602161 (rank : 116)	NC score	0.582742 (rank : 58)
Query Neighborhood Hits	357	Target Neighborhood Hits	291	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

LNX1_MOUSE
θ value	0.000786445 (rank : 117)	NC score	0.249273 (rank : 193)
Query Neighborhood Hits	357	Target Neighborhood Hits	377	Shared Neighborhood Hits	164
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SMRA3_MOUSE
θ value	0.000786445 (rank : 118)	NC score	0.268715 (rank : 184)
Query Neighborhood Hits	357	Target Neighborhood Hits	267	Shared Neighborhood Hits	175
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RN167_MOUSE
θ value	0.00102713 (rank : 119)	NC score	0.221462 (rank : 205)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	99
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_MOUSE
θ value	0.00102713 (rank : 120)	NC score	0.213157 (rank : 212)
Query Neighborhood Hits	357	Target Neighborhood Hits	164	Shared Neighborhood Hits	96
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

SMRA3_HUMAN
θ value	0.00102713 (rank : 121)	NC score	0.278538 (rank : 178)
Query Neighborhood Hits	357	Target Neighborhood Hits	265	Shared Neighborhood Hits	176
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI47_MOUSE
θ value	0.00102713 (rank : 122)	NC score	0.563869 (rank : 77)
Query Neighborhood Hits	357	Target Neighborhood Hits	295	Shared Neighborhood Hits	185
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

CBLC_MOUSE
θ value	0.00134147 (rank : 123)	NC score	0.251782 (rank : 190)
Query Neighborhood Hits	357	Target Neighborhood Hits	186	Shared Neighborhood Hits	132
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CROCC_MOUSE
θ value	0.00134147 (rank : 124)	NC score	0.060083 (rank : 345)
Query Neighborhood Hits	357	Target Neighborhood Hits	1460	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RAD18_HUMAN
θ value	0.00134147 (rank : 125)	NC score	0.358212 (rank : 138)
Query Neighborhood Hits	357	Target Neighborhood Hits	284	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

LNX1_HUMAN
θ value	0.00175202 (rank : 126)	NC score	0.247357 (rank : 194)
Query Neighborhood Hits	357	Target Neighborhood Hits	379	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

RN168_HUMAN
θ value	0.00175202 (rank : 127)	NC score	0.485327 (rank : 99)
Query Neighborhood Hits	357	Target Neighborhood Hits	370	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN179_HUMAN
θ value	0.00228821 (rank : 128)	NC score	0.492091 (rank : 96)
Query Neighborhood Hits	357	Target Neighborhood Hits	178	Shared Neighborhood Hits	129
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

AMFR2_HUMAN
θ value	0.00298849 (rank : 129)	NC score	0.273144 (rank : 181)
Query Neighborhood Hits	357	Target Neighborhood Hits	219	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

FSD1L_MOUSE
θ value	0.00298849 (rank : 130)	NC score	0.300873 (rank : 157)
Query Neighborhood Hits	357	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

K2C1B_MOUSE
θ value	0.00298849 (rank : 131)	NC score	0.036015 (rank : 404)
Query Neighborhood Hits	357	Target Neighborhood Hits	503	Shared Neighborhood Hits	61
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

RN168_MOUSE
θ value	0.00298849 (rank : 132)	NC score	0.472282 (rank : 104)
Query Neighborhood Hits	357	Target Neighborhood Hits	440	Shared Neighborhood Hits	191
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RAD18_MOUSE
θ value	0.00390308 (rank : 133)	NC score	0.366741 (rank : 135)
Query Neighborhood Hits	357	Target Neighborhood Hits	230	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN183_MOUSE
θ value	0.00390308 (rank : 134)	NC score	0.415195 (rank : 120)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TOPRS_HUMAN
θ value	0.00390308 (rank : 135)	NC score	0.283452 (rank : 175)
Query Neighborhood Hits	357	Target Neighborhood Hits	286	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.00390308 (rank : 136)	NC score	0.287947 (rank : 170)
Query Neighborhood Hits	357	Target Neighborhood Hits	263	Shared Neighborhood Hits	145
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

AMFR_MOUSE
θ value	0.00509761 (rank : 137)	NC score	0.269529 (rank : 183)
Query Neighborhood Hits	357	Target Neighborhood Hits	208	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CBLC_HUMAN
θ value	0.00869519 (rank : 138)	NC score	0.247302 (rank : 195)
Query Neighborhood Hits	357	Target Neighborhood Hits	173	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

RN141_HUMAN
θ value	0.00869519 (rank : 139)	NC score	0.380232 (rank : 128)
Query Neighborhood Hits	357	Target Neighborhood Hits	199	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.00869519 (rank : 140)	NC score	0.381017 (rank : 127)
Query Neighborhood Hits	357	Target Neighborhood Hits	200	Shared Neighborhood Hits	169
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN183_HUMAN
θ value	0.00869519 (rank : 141)	NC score	0.440858 (rank : 109)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	116
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI14_HUMAN
θ value	0.00869519 (rank : 142)	NC score	0.478363 (rank : 101)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	96
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI42_HUMAN
θ value	0.00869519 (rank : 143)	NC score	0.493020 (rank : 94)
Query Neighborhood Hits	357	Target Neighborhood Hits	283	Shared Neighborhood Hits	123
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UHRF2_HUMAN
θ value	0.00869519 (rank : 144)	NC score	0.292985 (rank : 163)
Query Neighborhood Hits	357	Target Neighborhood Hits	269	Shared Neighborhood Hits	155
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

PEX10_HUMAN
θ value	0.0113563 (rank : 145)	NC score	0.489816 (rank : 97)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	191
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRAF7_HUMAN
θ value	0.0113563 (rank : 146)	NC score	0.175101 (rank : 228)
Query Neighborhood Hits	357	Target Neighborhood Hits	482	Shared Neighborhood Hits	156
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

FSD1L_HUMAN
θ value	0.0148317 (rank : 147)	NC score	0.265386 (rank : 185)
Query Neighborhood Hits	357	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

RNF19_HUMAN
θ value	0.0148317 (rank : 148)	NC score	0.129380 (rank : 270)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	0.0148317 (rank : 149)	NC score	0.129590 (rank : 268)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

TRI14_MOUSE
θ value	0.0148317 (rank : 150)	NC score	0.471130 (rank : 105)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

UHRF2_MOUSE
θ value	0.0148317 (rank : 151)	NC score	0.287389 (rank : 172)
Query Neighborhood Hits	357	Target Neighborhood Hits	275	Shared Neighborhood Hits	151
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MYH14_HUMAN
θ value	0.0193708 (rank : 152)	NC score	0.035898 (rank : 405)
Query Neighborhood Hits	357	Target Neighborhood Hits	995	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RN125_MOUSE
θ value	0.0193708 (rank : 153)	NC score	0.430465 (rank : 113)
Query Neighborhood Hits	357	Target Neighborhood Hits	220	Shared Neighborhood Hits	161
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RNF14_HUMAN
θ value	0.0193708 (rank : 154)	NC score	0.087735 (rank : 302)
Query Neighborhood Hits	357	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

TRI49_HUMAN
θ value	0.0193708 (rank : 155)	NC score	0.502443 (rank : 91)
Query Neighborhood Hits	357	Target Neighborhood Hits	199	Shared Neighborhood Hits	154
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

DTX3L_HUMAN
θ value	0.0252991 (rank : 156)	NC score	0.218746 (rank : 208)
Query Neighborhood Hits	357	Target Neighborhood Hits	187	Shared Neighborhood Hits	131
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TRAF7_MOUSE
θ value	0.0252991 (rank : 157)	NC score	0.172141 (rank : 231)
Query Neighborhood Hits	357	Target Neighborhood Hits	470	Shared Neighborhood Hits	151
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

EXOC3_HUMAN
θ value	0.0330416 (rank : 158)	NC score	0.064301 (rank : 336)
Query Neighborhood Hits	357	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

EXOC3_MOUSE
θ value	0.0330416 (rank : 159)	NC score	0.064668 (rank : 334)
Query Neighborhood Hits	357	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

HOOK3_MOUSE
θ value	0.0330416 (rank : 160)	NC score	0.043262 (rank : 389)
Query Neighborhood Hits	357	Target Neighborhood Hits	1007	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

RN125_HUMAN
θ value	0.0330416 (rank : 161)	NC score	0.425992 (rank : 115)
Query Neighborhood Hits	357	Target Neighborhood Hits	230	Shared Neighborhood Hits	170
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RNF14_MOUSE
θ value	0.0330416 (rank : 162)	NC score	0.099322 (rank : 290)
Query Neighborhood Hits	357	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

KRHB2_MOUSE
θ value	0.0431538 (rank : 163)	NC score	0.027602 (rank : 426)
Query Neighborhood Hits	357	Target Neighborhood Hits	233	Shared Neighborhood Hits	36
SwissProt Accessions	Q99M74	Gene names	Krthb2, Krt2-20
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

PCNT_HUMAN
θ value	0.0431538 (rank : 164)	NC score	0.058013 (rank : 353)
Query Neighborhood Hits	357	Target Neighborhood Hits	1551	Shared Neighborhood Hits	108
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RAPSN_MOUSE
θ value	0.0431538 (rank : 165)	NC score	0.136835 (rank : 259)
Query Neighborhood Hits	357	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RBBP6_HUMAN
θ value	0.0431538 (rank : 166)	NC score	0.161386 (rank : 238)
Query Neighborhood Hits	357	Target Neighborhood Hits	1135	Shared Neighborhood Hits	139
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.0431538 (rank : 167)	NC score	0.178353 (rank : 227)
Query Neighborhood Hits	357	Target Neighborhood Hits	1014	Shared Neighborhood Hits	139
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RN166_HUMAN
θ value	0.0431538 (rank : 168)	NC score	0.437689 (rank : 111)
Query Neighborhood Hits	357	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.0431538 (rank : 169)	NC score	0.433506 (rank : 112)
Query Neighborhood Hits	357	Target Neighborhood Hits	248	Shared Neighborhood Hits	169
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF6_HUMAN
θ value	0.0431538 (rank : 170)	NC score	0.148980 (rank : 246)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

CBL_HUMAN
θ value	0.0563607 (rank : 171)	NC score	0.224891 (rank : 203)
Query Neighborhood Hits	357	Target Neighborhood Hits	353	Shared Neighborhood Hits	147
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0563607 (rank : 172)	NC score	0.220068 (rank : 207)
Query Neighborhood Hits	357	Target Neighborhood Hits	426	Shared Neighborhood Hits	151
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CP135_HUMAN
θ value	0.0563607 (rank : 173)	NC score	0.039660 (rank : 395)
Query Neighborhood Hits	357	Target Neighborhood Hits	1290	Shared Neighborhood Hits	94
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MEFV_HUMAN
θ value	0.0563607 (rank : 174)	NC score	0.440851 (rank : 110)
Query Neighborhood Hits	357	Target Neighborhood Hits	431	Shared Neighborhood Hits	119
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PLEC1_HUMAN
θ value	0.0563607 (rank : 175)	NC score	0.054753 (rank : 364)
Query Neighborhood Hits	357	Target Neighborhood Hits	1326	Shared Neighborhood Hits	103
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RN146_HUMAN
θ value	0.0563607 (rank : 176)	NC score	0.338996 (rank : 146)
Query Neighborhood Hits	357	Target Neighborhood Hits	162	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.0563607 (rank : 177)	NC score	0.336963 (rank : 148)
Query Neighborhood Hits	357	Target Neighborhood Hits	161	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN185_HUMAN
θ value	0.0563607 (rank : 178)	NC score	0.363666 (rank : 136)
Query Neighborhood Hits	357	Target Neighborhood Hits	213	Shared Neighborhood Hits	162
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.0563607 (rank : 179)	NC score	0.361909 (rank : 137)
Query Neighborhood Hits	357	Target Neighborhood Hits	211	Shared Neighborhood Hits	160
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

BFAR_HUMAN
θ value	0.0736092 (rank : 180)	NC score	0.423699 (rank : 117)
Query Neighborhood Hits	357	Target Neighborhood Hits	222	Shared Neighborhood Hits	171
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	0.0736092 (rank : 181)	NC score	0.418170 (rank : 119)
Query Neighborhood Hits	357	Target Neighborhood Hits	232	Shared Neighborhood Hits	168
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

GOGB1_HUMAN
θ value	0.0736092 (rank : 182)	NC score	0.060479 (rank : 344)
Query Neighborhood Hits	357	Target Neighborhood Hits	2297	Shared Neighborhood Hits	149
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HOOK3_HUMAN
θ value	0.0736092 (rank : 183)	NC score	0.042618 (rank : 390)
Query Neighborhood Hits	357	Target Neighborhood Hits	1070	Shared Neighborhood Hits	83
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

MK15_MOUSE
θ value	0.0736092 (rank : 184)	NC score	-0.004486 (rank : 459)
Query Neighborhood Hits	357	Target Neighborhood Hits	843	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

RN139_MOUSE
θ value	0.0736092 (rank : 185)	NC score	0.137119 (rank : 258)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RNF5_HUMAN
θ value	0.0736092 (rank : 186)	NC score	0.355317 (rank : 139)
Query Neighborhood Hits	357	Target Neighborhood Hits	206	Shared Neighborhood Hits	156
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

K2C1B_HUMAN
θ value	0.0961366 (rank : 187)	NC score	0.032554 (rank : 415)
Query Neighborhood Hits	357	Target Neighborhood Hits	542	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

K2C7_HUMAN
θ value	0.0961366 (rank : 188)	NC score	0.028579 (rank : 424)
Query Neighborhood Hits	357	Target Neighborhood Hits	369	Shared Neighborhood Hits	49
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

MEFV_MOUSE
θ value	0.0961366 (rank : 189)	NC score	0.462729 (rank : 106)
Query Neighborhood Hits	357	Target Neighborhood Hits	236	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RAPSN_HUMAN
θ value	0.0961366 (rank : 190)	NC score	0.130688 (rank : 266)
Query Neighborhood Hits	357	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RNF5_MOUSE
θ value	0.0961366 (rank : 191)	NC score	0.352465 (rank : 140)
Query Neighborhood Hits	357	Target Neighborhood Hits	206	Shared Neighborhood Hits	156
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

CP250_HUMAN
θ value	0.125558 (rank : 192)	NC score	0.058356 (rank : 352)
Query Neighborhood Hits	357	Target Neighborhood Hits	1805	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DTX3_MOUSE
θ value	0.125558 (rank : 193)	NC score	0.301224 (rank : 156)
Query Neighborhood Hits	357	Target Neighborhood Hits	202	Shared Neighborhood Hits	156
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DZIP3_HUMAN
θ value	0.125558 (rank : 194)	NC score	0.142249 (rank : 252)
Query Neighborhood Hits	357	Target Neighborhood Hits	399	Shared Neighborhood Hits	116
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

GOLI_MOUSE
θ value	0.125558 (rank : 195)	NC score	0.174736 (rank : 229)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

R113A_HUMAN
θ value	0.125558 (rank : 196)	NC score	0.261150 (rank : 186)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	125
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

UB7I3_MOUSE
θ value	0.125558 (rank : 197)	NC score	0.160923 (rank : 241)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

BRCA1_HUMAN
θ value	0.163984 (rank : 198)	NC score	0.405053 (rank : 122)
Query Neighborhood Hits	357	Target Neighborhood Hits	381	Shared Neighborhood Hits	184
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	0.163984 (rank : 199)	NC score	0.397455 (rank : 123)
Query Neighborhood Hits	357	Target Neighborhood Hits	436	Shared Neighborhood Hits	184
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CBLB_HUMAN
θ value	0.163984 (rank : 200)	NC score	0.216462 (rank : 210)
Query Neighborhood Hits	357	Target Neighborhood Hits	261	Shared Neighborhood Hits	140
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.163984 (rank : 201)	NC score	0.216788 (rank : 209)
Query Neighborhood Hits	357	Target Neighborhood Hits	277	Shared Neighborhood Hits	142
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

DTX3_HUMAN
θ value	0.163984 (rank : 202)	NC score	0.294994 (rank : 162)
Query Neighborhood Hits	357	Target Neighborhood Hits	198	Shared Neighborhood Hits	152
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

GOLI_HUMAN
θ value	0.163984 (rank : 203)	NC score	0.174546 (rank : 230)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF8_HUMAN
θ value	0.163984 (rank : 204)	NC score	0.385323 (rank : 126)
Query Neighborhood Hits	357	Target Neighborhood Hits	622	Shared Neighborhood Hits	238
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

CROCC_HUMAN
θ value	0.21417 (rank : 205)	NC score	0.054820 (rank : 362)
Query Neighborhood Hits	357	Target Neighborhood Hits	1409	Shared Neighborhood Hits	112
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FA55D_MOUSE
θ value	0.21417 (rank : 206)	NC score	0.046608 (rank : 384)
Query Neighborhood Hits	357	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q52KP5, Q8BKY4	Gene names	Fam55d
Domain Architecture	No domain graphic available
Description	Protein FAM55D precursor.

R113B_HUMAN
θ value	0.21417 (rank : 207)	NC score	0.278889 (rank : 176)
Query Neighborhood Hits	357	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RING1_HUMAN
θ value	0.21417 (rank : 208)	NC score	0.374384 (rank : 131)
Query Neighborhood Hits	357	Target Neighborhood Hits	219	Shared Neighborhood Hits	153
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.21417 (rank : 209)	NC score	0.368055 (rank : 134)
Query Neighborhood Hits	357	Target Neighborhood Hits	220	Shared Neighborhood Hits	153
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RNF38_HUMAN
θ value	0.21417 (rank : 210)	NC score	0.149358 (rank : 245)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

SIAH2_HUMAN
θ value	0.21417 (rank : 211)	NC score	0.079800 (rank : 310)
Query Neighborhood Hits	357	Target Neighborhood Hits	94	Shared Neighborhood Hits	50
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	0.21417 (rank : 212)	NC score	0.078232 (rank : 313)
Query Neighborhood Hits	357	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TRI52_HUMAN
θ value	0.21417 (rank : 213)	NC score	0.575139 (rank : 67)
Query Neighborhood Hits	357	Target Neighborhood Hits	213	Shared Neighborhood Hits	171
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

FA55D_HUMAN
θ value	0.279714 (rank : 214)	NC score	0.087275 (rank : 303)
Query Neighborhood Hits	357	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UWF7, Q6QDB4, Q9NXP5	Gene names	FAM55D, C11orf33
Domain Architecture	No domain graphic available
Description	Protein FAM55D precursor.

PWP2_MOUSE
θ value	0.279714 (rank : 215)	NC score	0.022823 (rank : 429)
Query Neighborhood Hits	357	Target Neighborhood Hits	309	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

RNF8_MOUSE
θ value	0.279714 (rank : 216)	NC score	0.395705 (rank : 124)
Query Neighborhood Hits	357	Target Neighborhood Hits	618	Shared Neighborhood Hits	241
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI48_HUMAN
θ value	0.279714 (rank : 217)	NC score	0.483211 (rank : 100)
Query Neighborhood Hits	357	Target Neighborhood Hits	192	Shared Neighborhood Hits	158
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

CM007_MOUSE
θ value	0.365318 (rank : 218)	NC score	0.251547 (rank : 191)
Query Neighborhood Hits	357	Target Neighborhood Hits	416	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

MYH14_MOUSE
θ value	0.365318 (rank : 219)	NC score	0.036877 (rank : 402)
Query Neighborhood Hits	357	Target Neighborhood Hits	1225	Shared Neighborhood Hits	99
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RBNS5_HUMAN
θ value	0.365318 (rank : 220)	NC score	0.030503 (rank : 420)
Query Neighborhood Hits	357	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RING2_HUMAN
θ value	0.365318 (rank : 221)	NC score	0.346512 (rank : 143)
Query Neighborhood Hits	357	Target Neighborhood Hits	201	Shared Neighborhood Hits	149
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.365318 (rank : 222)	NC score	0.347265 (rank : 141)
Query Neighborhood Hits	357	Target Neighborhood Hits	199	Shared Neighborhood Hits	149
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN122_HUMAN
θ value	0.365318 (rank : 223)	NC score	0.191104 (rank : 220)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN165_HUMAN
θ value	0.365318 (rank : 224)	NC score	0.187530 (rank : 222)
Query Neighborhood Hits	357	Target Neighborhood Hits	151	Shared Neighborhood Hits	94
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RNF12_MOUSE
θ value	0.365318 (rank : 225)	NC score	0.148842 (rank : 247)
Query Neighborhood Hits	357	Target Neighborhood Hits	159	Shared Neighborhood Hits	78
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF39_HUMAN
θ value	0.365318 (rank : 226)	NC score	0.475374 (rank : 103)
Query Neighborhood Hits	357	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

VPS36_HUMAN
θ value	0.365318 (rank : 227)	NC score	0.050598 (rank : 376)
Query Neighborhood Hits	357	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q86VN1, Q3ZCV7, Q5H9S1, Q5VXB6, Q9H8Z5, Q9Y3E3	Gene names	VPS36, C13orf9, EAP45
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 36 (ELL-associated protein of 45 kDa).

ZSWM2_MOUSE
θ value	0.365318 (rank : 228)	NC score	0.146039 (rank : 250)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

DZIP3_MOUSE
θ value	0.47712 (rank : 229)	NC score	0.140723 (rank : 253)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	123
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

K2C8_HUMAN
θ value	0.47712 (rank : 230)	NC score	0.031223 (rank : 417)
Query Neighborhood Hits	357	Target Neighborhood Hits	593	Shared Neighborhood Hits	65
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

PCGF2_HUMAN
θ value	0.47712 (rank : 231)	NC score	0.195062 (rank : 218)
Query Neighborhood Hits	357	Target Neighborhood Hits	222	Shared Neighborhood Hits	118
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.47712 (rank : 232)	NC score	0.194685 (rank : 219)
Query Neighborhood Hits	357	Target Neighborhood Hits	213	Shared Neighborhood Hits	117
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	0.47712 (rank : 233)	NC score	0.196278 (rank : 216)
Query Neighborhood Hits	357	Target Neighborhood Hits	161	Shared Neighborhood Hits	122
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.47712 (rank : 234)	NC score	0.195975 (rank : 217)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	120
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RFWD2_HUMAN
θ value	0.47712 (rank : 235)	NC score	0.246663 (rank : 196)
Query Neighborhood Hits	357	Target Neighborhood Hits	518	Shared Neighborhood Hits	191
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.47712 (rank : 236)	NC score	0.246115 (rank : 197)
Query Neighborhood Hits	357	Target Neighborhood Hits	535	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

T3JAM_MOUSE
θ value	0.47712 (rank : 237)	NC score	0.045656 (rank : 386)
Query Neighborhood Hits	357	Target Neighborhood Hits	535	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

BIRC7_HUMAN
θ value	0.62314 (rank : 238)	NC score	0.239255 (rank : 199)
Query Neighborhood Hits	357	Target Neighborhood Hits	185	Shared Neighborhood Hits	135
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CE290_HUMAN
θ value	0.62314 (rank : 239)	NC score	0.055073 (rank : 361)
Query Neighborhood Hits	357	Target Neighborhood Hits	1553	Shared Neighborhood Hits	119
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MKRN4_HUMAN
θ value	0.62314 (rank : 240)	NC score	0.114817 (rank : 281)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

PHLB1_HUMAN
θ value	0.62314 (rank : 241)	NC score	0.032557 (rank : 414)
Query Neighborhood Hits	357	Target Neighborhood Hits	1038	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PZRN3_MOUSE
θ value	0.62314 (rank : 242)	NC score	0.184172 (rank : 223)
Query Neighborhood Hits	357	Target Neighborhood Hits	447	Shared Neighborhood Hits	172
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RN133_HUMAN
θ value	0.62314 (rank : 243)	NC score	0.148449 (rank : 248)
Query Neighborhood Hits	357	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF38_MOUSE
θ value	0.62314 (rank : 244)	NC score	0.140277 (rank : 254)
Query Neighborhood Hits	357	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

VPS36_MOUSE
θ value	0.62314 (rank : 245)	NC score	0.047143 (rank : 383)
Query Neighborhood Hits	357	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XD6, Q9CVA3	Gene names	Vps36
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 36.

BIRC8_HUMAN
θ value	0.813845 (rank : 246)	NC score	0.110105 (rank : 284)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CENPU_MOUSE
θ value	0.813845 (rank : 247)	NC score	0.037055 (rank : 400)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

CM007_HUMAN
θ value	0.813845 (rank : 248)	NC score	0.224472 (rank : 204)
Query Neighborhood Hits	357	Target Neighborhood Hits	422	Shared Neighborhood Hits	161
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

KIFC1_HUMAN
θ value	0.813845 (rank : 249)	NC score	0.021099 (rank : 434)
Query Neighborhood Hits	357	Target Neighborhood Hits	545	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

MKRN3_HUMAN
θ value	0.813845 (rank : 250)	NC score	0.114233 (rank : 282)
Query Neighborhood Hits	357	Target Neighborhood Hits	165	Shared Neighborhood Hits	84
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

NPTX2_HUMAN
θ value	0.813845 (rank : 251)	NC score	0.022406 (rank : 431)
Query Neighborhood Hits	357	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	P47972, Q86XV7, Q96G70	Gene names	NPTX2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NUMA1_HUMAN
θ value	0.813845 (rank : 252)	NC score	0.048113 (rank : 381)
Query Neighborhood Hits	357	Target Neighborhood Hits	1523	Shared Neighborhood Hits	111
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PTPRS_HUMAN
θ value	0.813845 (rank : 253)	NC score	0.000571 (rank : 455)
Query Neighborhood Hits	357	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

RN122_MOUSE
θ value	0.813845 (rank : 254)	NC score	0.180251 (rank : 226)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN139_HUMAN
θ value	0.813845 (rank : 255)	NC score	0.123614 (rank : 275)
Query Neighborhood Hits	357	Target Neighborhood Hits	130	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RNF12_HUMAN
θ value	0.813845 (rank : 256)	NC score	0.138943 (rank : 255)
Query Neighborhood Hits	357	Target Neighborhood Hits	173	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

TRAF2_HUMAN
θ value	0.813845 (rank : 257)	NC score	0.138891 (rank : 256)
Query Neighborhood Hits	357	Target Neighborhood Hits	402	Shared Neighborhood Hits	123
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

UB7I3_HUMAN
θ value	0.813845 (rank : 258)	NC score	0.135090 (rank : 264)
Query Neighborhood Hits	357	Target Neighborhood Hits	136	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

IBRD3_HUMAN
θ value	1.06291 (rank : 259)	NC score	0.076606 (rank : 317)
Query Neighborhood Hits	357	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

ICAM5_HUMAN
θ value	1.06291 (rank : 260)	NC score	0.003413 (rank : 452)
Query Neighborhood Hits	357	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

MY18B_HUMAN
θ value	1.06291 (rank : 261)	NC score	0.027880 (rank : 425)
Query Neighborhood Hits	357	Target Neighborhood Hits	1299	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SPTN2_HUMAN
θ value	1.06291 (rank : 262)	NC score	0.042233 (rank : 391)
Query Neighborhood Hits	357	Target Neighborhood Hits	535	Shared Neighborhood Hits	60
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

TRAF2_MOUSE
θ value	1.06291 (rank : 263)	NC score	0.135577 (rank : 263)
Query Neighborhood Hits	357	Target Neighborhood Hits	394	Shared Neighborhood Hits	126
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

GOGA3_MOUSE
θ value	1.38821 (rank : 264)	NC score	0.051107 (rank : 370)
Query Neighborhood Hits	357	Target Neighborhood Hits	1437	Shared Neighborhood Hits	114
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

K2C8_MOUSE
θ value	1.38821 (rank : 265)	NC score	0.029594 (rank : 423)
Query Neighborhood Hits	357	Target Neighborhood Hits	576	Shared Neighborhood Hits	68
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

NEMO_HUMAN
θ value	1.38821 (rank : 266)	NC score	0.038343 (rank : 397)
Query Neighborhood Hits	357	Target Neighborhood Hits	820	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	1.38821 (rank : 267)	NC score	0.056939 (rank : 354)
Query Neighborhood Hits	357	Target Neighborhood Hits	658	Shared Neighborhood Hits	71
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

UHRF1_MOUSE
θ value	1.38821 (rank : 268)	NC score	0.234474 (rank : 202)
Query Neighborhood Hits	357	Target Neighborhood Hits	278	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

APC11_HUMAN
θ value	1.81305 (rank : 269)	NC score	0.063707 (rank : 338)
Query Neighborhood Hits	357	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

APC11_MOUSE
θ value	1.81305 (rank : 270)	NC score	0.067353 (rank : 326)
Query Neighborhood Hits	357	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

CP250_MOUSE
θ value	1.81305 (rank : 271)	NC score	0.058509 (rank : 351)
Query Neighborhood Hits	357	Target Neighborhood Hits	1583	Shared Neighborhood Hits	125
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

KDEL1_MOUSE
θ value	1.81305 (rank : 272)	NC score	0.014920 (rank : 442)
Query Neighborhood Hits	357	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHP7, Q8BPU6, Q8C528, Q8R591, Q9D8P1	Gene names	Kdelc1, Ep58
Domain Architecture	No domain graphic available
Description	KDEL motif-containing protein 1 precursor (ER protein 58).

MYH10_MOUSE
θ value	1.81305 (rank : 273)	NC score	0.037350 (rank : 399)
Query Neighborhood Hits	357	Target Neighborhood Hits	1612	Shared Neighborhood Hits	119
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PZRN3_HUMAN
θ value	1.81305 (rank : 274)	NC score	0.180995 (rank : 224)
Query Neighborhood Hits	357	Target Neighborhood Hits	461	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RNF26_HUMAN
θ value	1.81305 (rank : 275)	NC score	0.129378 (rank : 271)
Query Neighborhood Hits	357	Target Neighborhood Hits	95	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

CCHCR_HUMAN
θ value	2.36792 (rank : 276)	NC score	0.039742 (rank : 394)
Query Neighborhood Hits	357	Target Neighborhood Hits	717	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCNL1_HUMAN
θ value	2.36792 (rank : 277)	NC score	0.016249 (rank : 440)
Query Neighborhood Hits	357	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

K0552_HUMAN
θ value	2.36792 (rank : 278)	NC score	0.035781 (rank : 406)
Query Neighborhood Hits	357	Target Neighborhood Hits	442	Shared Neighborhood Hits	61
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

LIPA1_HUMAN
θ value	2.36792 (rank : 279)	NC score	0.032768 (rank : 413)
Query Neighborhood Hits	357	Target Neighborhood Hits	1294	Shared Neighborhood Hits	95
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MKRN1_HUMAN
θ value	2.36792 (rank : 280)	NC score	0.093721 (rank : 295)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	2.36792 (rank : 281)	NC score	0.092788 (rank : 297)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN3_MOUSE
θ value	2.36792 (rank : 282)	NC score	0.098937 (rank : 291)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

RNF24_MOUSE
θ value	2.36792 (rank : 283)	NC score	0.149959 (rank : 244)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

BIRC2_MOUSE
θ value	3.0926 (rank : 284)	NC score	0.077086 (rank : 316)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

CNTRB_HUMAN
θ value	3.0926 (rank : 285)	NC score	0.043271 (rank : 388)
Query Neighborhood Hits	357	Target Neighborhood Hits	690	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

IBRD2_HUMAN
θ value	3.0926 (rank : 286)	NC score	0.066098 (rank : 331)
Query Neighborhood Hits	357	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

KRHB2_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.021321 (rank : 433)
Query Neighborhood Hits	357	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

LAMC3_HUMAN
θ value	3.0926 (rank : 288)	NC score	0.002634 (rank : 453)
Query Neighborhood Hits	357	Target Neighborhood Hits	588	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MYH7_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.031306 (rank : 416)
Query Neighborhood Hits	357	Target Neighborhood Hits	1559	Shared Neighborhood Hits	111
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PCGF6_HUMAN
θ value	3.0926 (rank : 290)	NC score	0.209008 (rank : 215)
Query Neighborhood Hits	357	Target Neighborhood Hits	178	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	3.0926 (rank : 291)	NC score	0.211042 (rank : 214)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	122
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCNT_MOUSE
θ value	3.0926 (rank : 292)	NC score	0.048866 (rank : 379)
Query Neighborhood Hits	357	Target Neighborhood Hits	1207	Shared Neighborhood Hits	105
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RNF24_HUMAN
θ value	3.0926 (rank : 293)	NC score	0.146841 (rank : 249)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

BIRC3_MOUSE
θ value	4.03905 (rank : 294)	NC score	0.067245 (rank : 327)
Query Neighborhood Hits	357	Target Neighborhood Hits	113	Shared Neighborhood Hits	68
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

CE025_HUMAN
θ value	4.03905 (rank : 295)	NC score	0.019919 (rank : 436)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

IBRD2_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.065162 (rank : 333)
Query Neighborhood Hits	357	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

MRCKG_HUMAN
θ value	4.03905 (rank : 297)	NC score	-0.001436 (rank : 458)
Query Neighborhood Hits	357	Target Neighborhood Hits	1519	Shared Neighborhood Hits	69
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MYH10_HUMAN
θ value	4.03905 (rank : 298)	NC score	0.035516 (rank : 407)
Query Neighborhood Hits	357	Target Neighborhood Hits	1620	Shared Neighborhood Hits	121
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NCOA4_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.021789 (rank : 432)
Query Neighborhood Hits	357	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).

RIMB1_HUMAN
θ value	4.03905 (rank : 300)	NC score	0.025657 (rank : 428)
Query Neighborhood Hits	357	Target Neighborhood Hits	1479	Shared Neighborhood Hits	77
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RNF17_HUMAN
θ value	4.03905 (rank : 301)	NC score	0.045502 (rank : 387)
Query Neighborhood Hits	357	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

RNF32_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.142439 (rank : 251)
Query Neighborhood Hits	357	Target Neighborhood Hits	133	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF41_HUMAN
θ value	4.03905 (rank : 303)	NC score	0.313415 (rank : 153)
Query Neighborhood Hits	357	Target Neighborhood Hits	226	Shared Neighborhood Hits	169
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	4.03905 (rank : 304)	NC score	0.313018 (rank : 154)
Query Neighborhood Hits	357	Target Neighborhood Hits	224	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	4.03905 (rank : 305)	NC score	0.297673 (rank : 159)
Query Neighborhood Hits	357	Target Neighborhood Hits	212	Shared Neighborhood Hits	160
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	4.03905 (rank : 306)	NC score	0.292541 (rank : 164)
Query Neighborhood Hits	357	Target Neighborhood Hits	212	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RRMJ3_MOUSE
θ value	4.03905 (rank : 307)	NC score	0.014437 (rank : 445)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

RUFY1_MOUSE
θ value	4.03905 (rank : 308)	NC score	0.032866 (rank : 412)
Query Neighborhood Hits	357	Target Neighborhood Hits	765	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SKI_HUMAN
θ value	4.03905 (rank : 309)	NC score	0.022738 (rank : 430)
Query Neighborhood Hits	357	Target Neighborhood Hits	423	Shared Neighborhood Hits	45
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

UHRF1_HUMAN
θ value	4.03905 (rank : 310)	NC score	0.234772 (rank : 201)
Query Neighborhood Hits	357	Target Neighborhood Hits	272	Shared Neighborhood Hits	149
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CENPF_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.052096 (rank : 366)
Query Neighborhood Hits	357	Target Neighborhood Hits	1932	Shared Neighborhood Hits	141
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CT004_MOUSE
θ value	5.27518 (rank : 312)	NC score	0.015354 (rank : 441)
Query Neighborhood Hits	357	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2V5, Q3TM16, Q8VBU9	Gene names
Domain Architecture
Description	Protein C20orf4 homolog.

FLIP1_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.037036 (rank : 401)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GCC2_HUMAN
θ value	5.27518 (rank : 314)	NC score	0.047971 (rank : 382)
Query Neighborhood Hits	357	Target Neighborhood Hits	1558	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA1_MOUSE
θ value	5.27518 (rank : 315)	NC score	0.035223 (rank : 408)
Query Neighborhood Hits	357	Target Neighborhood Hits	994	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MKRN2_MOUSE
θ value	5.27518 (rank : 316)	NC score	0.093739 (rank : 294)
Query Neighborhood Hits	357	Target Neighborhood Hits	130	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MLL2_HUMAN
θ value	5.27518 (rank : 317)	NC score	0.040478 (rank : 393)
Query Neighborhood Hits	357	Target Neighborhood Hits	1788	Shared Neighborhood Hits	89
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NF2L1_HUMAN
θ value	5.27518 (rank : 318)	NC score	0.014630 (rank : 443)
Query Neighborhood Hits	357	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
θ value	5.27518 (rank : 319)	NC score	0.014596 (rank : 444)
Query Neighborhood Hits	357	Target Neighborhood Hits	185	Shared Neighborhood Hits	15
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

NPTX2_MOUSE
θ value	5.27518 (rank : 320)	NC score	0.014280 (rank : 446)
Query Neighborhood Hits	357	Target Neighborhood Hits	79	Shared Neighborhood Hits	11
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

RBP24_HUMAN
θ value	5.27518 (rank : 321)	NC score	0.048248 (rank : 380)
Query Neighborhood Hits	357	Target Neighborhood Hits	1559	Shared Neighborhood Hits	130
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RUFY1_HUMAN
θ value	5.27518 (rank : 322)	NC score	0.033802 (rank : 410)
Query Neighborhood Hits	357	Target Neighborhood Hits	848	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

TAOK2_HUMAN
θ value	5.27518 (rank : 323)	NC score	-0.005884 (rank : 460)
Query Neighborhood Hits	357	Target Neighborhood Hits	1172	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

TPM4_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.030617 (rank : 419)
Query Neighborhood Hits	357	Target Neighborhood Hits	703	Shared Neighborhood Hits	73
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

ZDH19_MOUSE
θ value	5.27518 (rank : 325)	NC score	0.006182 (rank : 449)
Query Neighborhood Hits	357	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q810M5	Gene names	Zdhhc19
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC19 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 19) (DHHC-19).

ZSWM2_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.135989 (rank : 260)
Query Neighborhood Hits	357	Target Neighborhood Hits	151	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ANR47_HUMAN
θ value	6.88961 (rank : 327)	NC score	-0.001232 (rank : 457)
Query Neighborhood Hits	357	Target Neighborhood Hits	369	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ATS4_MOUSE
θ value	6.88961 (rank : 328)	NC score	0.000202 (rank : 456)
Query Neighborhood Hits	357	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

FYCO1_HUMAN
θ value	6.88961 (rank : 329)	NC score	0.036713 (rank : 403)
Query Neighborhood Hits	357	Target Neighborhood Hits	1149	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GOGA4_MOUSE
θ value	6.88961 (rank : 330)	NC score	0.056516 (rank : 356)
Query Neighborhood Hits	357	Target Neighborhood Hits	1939	Shared Neighborhood Hits	136
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LRSM1_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.053920 (rank : 365)
Query Neighborhood Hits	357	Target Neighborhood Hits	874	Shared Neighborhood Hits	127
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MIB2_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.041469 (rank : 392)
Query Neighborhood Hits	357	Target Neighborhood Hits	438	Shared Neighborhood Hits	89
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MKRN2_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.089454 (rank : 300)
Query Neighborhood Hits	357	Target Neighborhood Hits	129	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MYH9_MOUSE
θ value	6.88961 (rank : 334)	NC score	0.037886 (rank : 398)
Query Neighborhood Hits	357	Target Neighborhood Hits	1829	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYLIP_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.061799 (rank : 342)
Query Neighborhood Hits	357	Target Neighborhood Hits	162	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NFH_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.013652 (rank : 447)
Query Neighborhood Hits	357	Target Neighborhood Hits	2247	Shared Neighborhood Hits	77
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NSF1C_MOUSE
θ value	6.88961 (rank : 337)	NC score	0.010982 (rank : 448)
Query Neighborhood Hits	357	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

SYNE1_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.059326 (rank : 349)
Query Neighborhood Hits	357	Target Neighborhood Hits	1484	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

AAKG2_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.006047 (rank : 450)
Query Neighborhood Hits	357	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

AMOL2_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.029990 (rank : 421)
Query Neighborhood Hits	357	Target Neighborhood Hits	603	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.031054 (rank : 418)
Query Neighborhood Hits	357	Target Neighborhood Hits	591	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

BIRC3_HUMAN
θ value	8.99809 (rank : 342)	NC score	0.078508 (rank : 312)
Query Neighborhood Hits	357	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

CP135_MOUSE
θ value	8.99809 (rank : 343)	NC score	0.035071 (rank : 409)
Query Neighborhood Hits	357	Target Neighborhood Hits	1278	Shared Neighborhood Hits	96
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

FBX41_HUMAN
θ value	8.99809 (rank : 344)	NC score	0.018059 (rank : 438)
Query Neighborhood Hits	357	Target Neighborhood Hits	475	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	8.99809 (rank : 345)	NC score	0.019178 (rank : 437)
Query Neighborhood Hits	357	Target Neighborhood Hits	430	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

GOGA3_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.038614 (rank : 396)
Query Neighborhood Hits	357	Target Neighborhood Hits	1317	Shared Neighborhood Hits	100
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA4_HUMAN
θ value	8.99809 (rank : 347)	NC score	0.046403 (rank : 385)
Query Neighborhood Hits	357	Target Neighborhood Hits	2034	Shared Neighborhood Hits	143
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HIP1R_HUMAN
θ value	8.99809 (rank : 348)	NC score	0.029711 (rank : 422)
Query Neighborhood Hits	357	Target Neighborhood Hits	809	Shared Neighborhood Hits	78
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

K2C1_HUMAN
θ value	8.99809 (rank : 349)	NC score	0.026480 (rank : 427)
Query Neighborhood Hits	357	Target Neighborhood Hits	624	Shared Neighborhood Hits	66
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

KIF5C_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.017808 (rank : 439)
Query Neighborhood Hits	357	Target Neighborhood Hits	974	Shared Neighborhood Hits	79
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KRHB4_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.020770 (rank : 435)
Query Neighborhood Hits	357	Target Neighborhood Hits	344	Shared Neighborhood Hits	44
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

LAMB3_HUMAN
θ value	8.99809 (rank : 352)	NC score	0.004309 (rank : 451)
Query Neighborhood Hits	357	Target Neighborhood Hits	461	Shared Neighborhood Hits	38
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

MNAB_HUMAN
θ value	8.99809 (rank : 353)	NC score	0.135601 (rank : 262)
Query Neighborhood Hits	357	Target Neighborhood Hits	196	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	8.99809 (rank : 354)	NC score	0.134924 (rank : 265)
Query Neighborhood Hits	357	Target Neighborhood Hits	231	Shared Neighborhood Hits	105
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RABE2_MOUSE
θ value	8.99809 (rank : 355)	NC score	0.033036 (rank : 411)
Query Neighborhood Hits	357	Target Neighborhood Hits	598	Shared Neighborhood Hits	66
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RN169_HUMAN
θ value	8.99809 (rank : 356)	NC score	0.297197 (rank : 160)
Query Neighborhood Hits	357	Target Neighborhood Hits	203	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SNX12_HUMAN
θ value	8.99809 (rank : 357)	NC score	0.002616 (rank : 454)
Query Neighborhood Hits	357	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMY4, Q8WUG9	Gene names	SNX12
Domain Architecture
Description	Sorting nexin-12.

AIRE_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.077223 (rank : 315)
Query Neighborhood Hits	357	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.076068 (rank : 318)
Query Neighborhood Hits	357	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ARI2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.063952 (rank : 337)
Query Neighborhood Hits	357	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.063218 (rank : 340)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

BARD1_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.091054 (rank : 299)
Query Neighborhood Hits	357	Target Neighborhood Hits	427	Shared Neighborhood Hits	91
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.082234 (rank : 309)
Query Neighborhood Hits	357	Target Neighborhood Hits	411	Shared Neighborhood Hits	87
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.054812 (rank : 363)
Query Neighborhood Hits	357	Target Neighborhood Hits	693	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.050623 (rank : 375)
Query Neighborhood Hits	357	Target Neighborhood Hits	394	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.062847 (rank : 341)
Query Neighborhood Hits	357	Target Neighborhood Hits	780	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.059683 (rank : 348)
Query Neighborhood Hits	357	Target Neighborhood Hits	744	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.060012 (rank : 346)
Query Neighborhood Hits	357	Target Neighborhood Hits	803	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BIRC2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.072883 (rank : 321)
Query Neighborhood Hits	357	Target Neighborhood Hits	142	Shared Neighborhood Hits	80
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BPTF_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.056933 (rank : 355)
Query Neighborhood Hits	357	Target Neighborhood Hits	786	Shared Neighborhood Hits	45
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRAP_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.088970 (rank : 301)
Query Neighborhood Hits	357	Target Neighborhood Hits	560	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.084790 (rank : 306)
Query Neighborhood Hits	357	Target Neighborhood Hits	409	Shared Neighborhood Hits	111
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRE1A_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.071394 (rank : 322)
Query Neighborhood Hits	357	Target Neighborhood Hits	1071	Shared Neighborhood Hits	182
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.068148 (rank : 325)
Query Neighborhood Hits	357	Target Neighborhood Hits	1025	Shared Neighborhood Hits	176
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.092535 (rank : 298)
Query Neighborhood Hits	357	Target Neighborhood Hits	1040	Shared Neighborhood Hits	201
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.094986 (rank : 293)
Query Neighborhood Hits	357	Target Neighborhood Hits	970	Shared Neighborhood Hits	203
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BSPRY_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.340415 (rank : 145)
Query Neighborhood Hits	357	Target Neighborhood Hits	115	Shared Neighborhood Hits	78
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.347103 (rank : 142)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.291218 (rank : 166)
Query Neighborhood Hits	357	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.295725 (rank : 161)
Query Neighborhood Hits	357	Target Neighborhood Hits	252	Shared Neighborhood Hits	62
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.278764 (rank : 177)
Query Neighborhood Hits	357	Target Neighborhood Hits	185	Shared Neighborhood Hits	60
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.288815 (rank : 168)
Query Neighborhood Hits	357	Target Neighborhood Hits	191	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.277024 (rank : 180)
Query Neighborhood Hits	357	Target Neighborhood Hits	195	Shared Neighborhood Hits	57
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.288540 (rank : 169)
Query Neighborhood Hits	357	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.291548 (rank : 165)
Query Neighborhood Hits	357	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.284037 (rank : 174)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.272595 (rank : 182)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.287623 (rank : 171)
Query Neighborhood Hits	357	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CNOT4_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.068262 (rank : 324)
Query Neighborhood Hits	357	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.064603 (rank : 335)
Query Neighborhood Hits	357	Target Neighborhood Hits	277	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

ERMAP_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.332376 (rank : 151)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.305958 (rank : 155)
Query Neighborhood Hits	357	Target Neighborhood Hits	231	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

LRSM1_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.056010 (rank : 358)
Query Neighborhood Hits	357	Target Neighborhood Hits	1078	Shared Neighborhood Hits	136
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LY10_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.093674 (rank : 296)
Query Neighborhood Hits	357	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MAT1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.073697 (rank : 319)
Query Neighborhood Hits	357	Target Neighborhood Hits	179	Shared Neighborhood Hits	53
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.073576 (rank : 320)
Query Neighborhood Hits	357	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MGRN1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.118621 (rank : 278)
Query Neighborhood Hits	357	Target Neighborhood Hits	192	Shared Neighborhood Hits	100
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.116702 (rank : 279)
Query Neighborhood Hits	357	Target Neighborhood Hits	149	Shared Neighborhood Hits	97
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MIB1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.051630 (rank : 369)
Query Neighborhood Hits	357	Target Neighborhood Hits	470	Shared Neighborhood Hits	96
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.051859 (rank : 367)
Query Neighborhood Hits	357	Target Neighborhood Hits	471	Shared Neighborhood Hits	95
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

NEUL1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.060538 (rank : 343)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.058584 (rank : 350)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

PEX2_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.050042 (rank : 378)
Query Neighborhood Hits	357	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

PF21A_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.066214 (rank : 330)
Query Neighborhood Hits	357	Target Neighborhood Hits	303	Shared Neighborhood Hits	30
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.067025 (rank : 328)
Query Neighborhood Hits	357	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.050798 (rank : 373)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.055415 (rank : 360)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.055986 (rank : 359)
Query Neighborhood Hits	357	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PJA1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.122961 (rank : 276)
Query Neighborhood Hits	357	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.115346 (rank : 280)
Query Neighborhood Hits	357	Target Neighborhood Hits	145	Shared Neighborhood Hits	84
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PKCB1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.063663 (rank : 339)
Query Neighborhood Hits	357	Target Neighborhood Hits	488	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PZRN4_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.170602 (rank : 232)
Query Neighborhood Hits	357	Target Neighborhood Hits	438	Shared Neighborhood Hits	174
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RAG1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.259163 (rank : 187)
Query Neighborhood Hits	357	Target Neighborhood Hits	203	Shared Neighborhood Hits	134
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.249492 (rank : 192)
Query Neighborhood Hits	357	Target Neighborhood Hits	189	Shared Neighborhood Hits	134
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RBX2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.050763 (rank : 374)
Query Neighborhood Hits	357	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.050894 (rank : 372)
Query Neighborhood Hits	357	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RC3H1_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.157442 (rank : 242)
Query Neighborhood Hits	357	Target Neighborhood Hits	433	Shared Neighborhood Hits	124
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.164680 (rank : 237)
Query Neighborhood Hits	357	Target Neighborhood Hits	244	Shared Neighborhood Hits	119
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFFL_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.059692 (rank : 347)
Query Neighborhood Hits	357	Target Neighborhood Hits	175	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.056277 (rank : 357)
Query Neighborhood Hits	357	Target Neighborhood Hits	145	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFPL1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.334279 (rank : 150)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.337499 (rank : 147)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.343215 (rank : 144)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	99
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RKHD1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.101579 (rank : 287)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	69
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN103_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.104807 (rank : 285)
Query Neighborhood Hits	357	Target Neighborhood Hits	153	Shared Neighborhood Hits	88
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.104441 (rank : 286)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN123_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.077904 (rank : 314)
Query Neighborhood Hits	357	Target Neighborhood Hits	175	Shared Neighborhood Hits	113
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.079179 (rank : 311)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	115
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN126_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.123722 (rank : 274)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.135767 (rank : 261)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN175_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.051770 (rank : 368)
Query Neighborhood Hits	357	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

RNF11_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.100868 (rank : 288)
Query Neighborhood Hits	357	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.100384 (rank : 289)
Query Neighborhood Hits	357	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF17_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.050510 (rank : 377)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	35
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RNF32_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.112675 (rank : 283)
Query Neighborhood Hits	357	Target Neighborhood Hits	129	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.084145 (rank : 308)
Query Neighborhood Hits	357	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.085921 (rank : 304)
Query Neighborhood Hits	357	Target Neighborhood Hits	160	Shared Neighborhood Hits	83
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF37_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.065486 (rank : 332)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

SIA1B_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.051050 (rank : 371)
Query Neighborhood Hits	357	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SP110_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.069827 (rank : 323)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SPRY4_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.290327 (rank : 167)
Query Neighborhood Hits	357	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.298278 (rank : 158)
Query Neighborhood Hits	357	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRAF3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.120132 (rank : 277)
Query Neighborhood Hits	357	Target Neighborhood Hits	463	Shared Neighborhood Hits	152
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.129442 (rank : 269)
Query Neighborhood Hits	357	Target Neighborhood Hits	476	Shared Neighborhood Hits	159
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.165162 (rank : 234)
Query Neighborhood Hits	357	Target Neighborhood Hits	373	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.095657 (rank : 292)
Query Neighborhood Hits	357	Target Neighborhood Hits	338	Shared Neighborhood Hits	102
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.151586 (rank : 243)
Query Neighborhood Hits	357	Target Neighborhood Hits	396	Shared Neighborhood Hits	142
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.180324 (rank : 225)
Query Neighborhood Hits	357	Target Neighborhood Hits	355	Shared Neighborhood Hits	152
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF6_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.238130 (rank : 200)
Query Neighborhood Hits	357	Target Neighborhood Hits	267	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.241632 (rank : 198)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	162
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAIP_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.126454 (rank : 272)
Query Neighborhood Hits	357	Target Neighborhood Hits	780	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.124472 (rank : 273)
Query Neighborhood Hits	357	Target Neighborhood Hits	745	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI16_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.393348 (rank : 125)
Query Neighborhood Hits	357	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI44_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.369801 (rank : 133)
Query Neighborhood Hits	357	Target Neighborhood Hits	393	Shared Neighborhood Hits	104
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.374928 (rank : 130)
Query Neighborhood Hits	357	Target Neighborhood Hits	327	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TTC3_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.066894 (rank : 329)
Query Neighborhood Hits	357	Target Neighborhood Hits	664	Shared Neighborhood Hits	112
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

ZN363_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.084176 (rank : 307)
Query Neighborhood Hits	357	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.085408 (rank : 305)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN364_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.137781 (rank : 257)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.130286 (rank : 267)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

Hits sorted by NC score

TRIM3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	357	Target Neighborhood Hits	357	Shared Neighborhood Hits	357
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
NC score	0.997098 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	357	Target Neighborhood Hits	351	Shared Neighborhood Hits	337
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM2_MOUSE
NC score	0.973521 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	357	Target Neighborhood Hits	331	Shared Neighborhood Hits	253
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM2_HUMAN
NC score	0.973426 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	357	Target Neighborhood Hits	330	Shared Neighborhood Hits	254
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI56_MOUSE
NC score	0.785838 (rank : 5)	θ value	7.80994e-28 (rank : 8)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	184
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.772793 (rank : 6)	θ value	5.0505e-35 (rank : 7)
Query Neighborhood Hits	357	Target Neighborhood Hits	339	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI59_HUMAN
NC score	0.746267 (rank : 7)	θ value	1.63225e-17 (rank : 14)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	201
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
NC score	0.742172 (rank : 8)	θ value	1.99529e-15 (rank : 22)
Query Neighborhood Hits	357	Target Neighborhood Hits	292	Shared Neighborhood Hits	207
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI13_MOUSE
NC score	0.738849 (rank : 9)	θ value	1.29331e-14 (rank : 26)
Query Neighborhood Hits	357	Target Neighborhood Hits	282	Shared Neighborhood Hits	219
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.738080 (rank : 10)	θ value	3.40345e-15 (rank : 24)
Query Neighborhood Hits	357	Target Neighborhood Hits	274	Shared Neighborhood Hits	212
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI45_HUMAN
NC score	0.734423 (rank : 11)	θ value	1.42001e-37 (rank : 5)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI54_MOUSE
NC score	0.729661 (rank : 12)	θ value	2.20094e-22 (rank : 9)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	158
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_HUMAN
NC score	0.728355 (rank : 13)	θ value	6.40375e-22 (rank : 10)
Query Neighborhood Hits	357	Target Neighborhood Hits	209	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI45_MOUSE
NC score	0.721514 (rank : 14)	θ value	5.96599e-36 (rank : 6)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	112
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI63_HUMAN
NC score	0.720363 (rank : 15)	θ value	7.32683e-18 (rank : 13)
Query Neighborhood Hits	357	Target Neighborhood Hits	298	Shared Neighborhood Hits	171
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
NC score	0.716987 (rank : 16)	θ value	8.95645e-16 (rank : 20)
Query Neighborhood Hits	357	Target Neighborhood Hits	240	Shared Neighborhood Hits	169
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI55_HUMAN
NC score	0.708163 (rank : 17)	θ value	4.74913e-17 (rank : 15)
Query Neighborhood Hits	357	Target Neighborhood Hits	292	Shared Neighborhood Hits	168
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI32_HUMAN
NC score	0.702202 (rank : 18)	θ value	7.09661e-13 (rank : 35)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	183
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.696179 (rank : 19)	θ value	4.59992e-12 (rank : 39)
Query Neighborhood Hits	357	Target Neighborhood Hits	271	Shared Neighborhood Hits	184
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI65_HUMAN
NC score	0.694427 (rank : 20)	θ value	8.10077e-17 (rank : 16)
Query Neighborhood Hits	357	Target Neighborhood Hits	330	Shared Neighborhood Hits	229
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI31_HUMAN
NC score	0.681199 (rank : 21)	θ value	1.02475e-11 (rank : 40)
Query Neighborhood Hits	357	Target Neighborhood Hits	299	Shared Neighborhood Hits	208
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI65_MOUSE
NC score	0.670099 (rank : 22)	θ value	6.85773e-16 (rank : 18)
Query Neighborhood Hits	357	Target Neighborhood Hits	340	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI74_HUMAN
NC score	0.664307 (rank : 23)	θ value	9.92553e-07 (rank : 86)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	199
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI73_HUMAN
NC score	0.663755 (rank : 24)	θ value	1.69304e-06 (rank : 91)
Query Neighborhood Hits	357	Target Neighborhood Hits	258	Shared Neighborhood Hits	204
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM8_MOUSE
NC score	0.642718 (rank : 25)	θ value	7.59969e-07 (rank : 84)
Query Neighborhood Hits	357	Target Neighborhood Hits	674	Shared Neighborhood Hits	222
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.640372 (rank : 26)	θ value	3.77169e-06 (rank : 98)
Query Neighborhood Hits	357	Target Neighborhood Hits	650	Shared Neighborhood Hits	224
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI12_MOUSE
NC score	0.639934 (rank : 27)	θ value	5.08577e-11 (rank : 47)
Query Neighborhood Hits	357	Target Neighborhood Hits	387	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM1_HUMAN
NC score	0.639600 (rank : 28)	θ value	5.08577e-11 (rank : 49)
Query Neighborhood Hits	357	Target Neighborhood Hits	345	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI18_MOUSE
NC score	0.637559 (rank : 29)	θ value	1.47974e-10 (rank : 50)
Query Neighborhood Hits	357	Target Neighborhood Hits	292	Shared Neighborhood Hits	189
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRIM1_MOUSE
NC score	0.637479 (rank : 30)	θ value	2.98157e-11 (rank : 45)
Query Neighborhood Hits	357	Target Neighborhood Hits	361	Shared Neighborhood Hits	200
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI18_HUMAN
NC score	0.634258 (rank : 31)	θ value	7.34386e-10 (rank : 57)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	189
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI35_MOUSE
NC score	0.632833 (rank : 32)	θ value	2.98157e-11 (rank : 44)
Query Neighborhood Hits	357	Target Neighborhood Hits	465	Shared Neighborhood Hits	227
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI50_MOUSE
NC score	0.625123 (rank : 33)	θ value	4.30538e-10 (rank : 54)
Query Neighborhood Hits	357	Target Neighborhood Hits	326	Shared Neighborhood Hits	219
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
NC score	0.623942 (rank : 34)	θ value	7.34386e-10 (rank : 58)
Query Neighborhood Hits	357	Target Neighborhood Hits	294	Shared Neighborhood Hits	212
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI36_HUMAN
NC score	0.621018 (rank : 35)	θ value	2.0648e-12 (rank : 36)
Query Neighborhood Hits	357	Target Neighborhood Hits	282	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI26_HUMAN
NC score	0.615563 (rank : 36)	θ value	3.29651e-10 (rank : 52)
Query Neighborhood Hits	357	Target Neighborhood Hits	335	Shared Neighborhood Hits	208
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI10_MOUSE
NC score	0.614846 (rank : 37)	θ value	3.40345e-15 (rank : 23)
Query Neighborhood Hits	357	Target Neighborhood Hits	285	Shared Neighborhood Hits	200
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI36_MOUSE
NC score	0.614720 (rank : 38)	θ value	5.43371e-13 (rank : 34)
Query Neighborhood Hits	357	Target Neighborhood Hits	266	Shared Neighborhood Hits	162
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI26_MOUSE
NC score	0.612957 (rank : 39)	θ value	2.98157e-11 (rank : 42)
Query Neighborhood Hits	357	Target Neighborhood Hits	339	Shared Neighborhood Hits	210
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI10_HUMAN
NC score	0.611017 (rank : 40)	θ value	2.52405e-10 (rank : 51)
Query Neighborhood Hits	357	Target Neighborhood Hits	315	Shared Neighborhood Hits	209
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI35_HUMAN
NC score	0.610894 (rank : 41)	θ value	6.21693e-09 (rank : 69)
Query Neighborhood Hits	357	Target Neighborhood Hits	382	Shared Neighborhood Hits	214
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
NC score	0.603207 (rank : 42)	θ value	1.25267e-09 (rank : 60)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	171
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.602806 (rank : 43)	θ value	1.25267e-09 (rank : 61)
Query Neighborhood Hits	357	Target Neighborhood Hits	316	Shared Neighborhood Hits	170
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI30_MOUSE
NC score	0.602733 (rank : 44)	θ value	2.36244e-08 (rank : 74)
Query Neighborhood Hits	357	Target Neighborhood Hits	434	Shared Neighborhood Hits	211
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI62_MOUSE
NC score	0.601689 (rank : 45)	θ value	4.91457e-14 (rank : 28)
Query Neighborhood Hits	357	Target Neighborhood Hits	478	Shared Neighborhood Hits	212
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM7_MOUSE
NC score	0.600659 (rank : 46)	θ value	1.09485e-13 (rank : 30)
Query Neighborhood Hits	357	Target Neighborhood Hits	358	Shared Neighborhood Hits	207
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI40_HUMAN
NC score	0.600269 (rank : 47)	θ value	3.77169e-06 (rank : 97)
Query Neighborhood Hits	357	Target Neighborhood Hits	279	Shared Neighborhood Hits	187
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI62_HUMAN
NC score	0.599440 (rank : 48)	θ value	1.42992e-13 (rank : 31)
Query Neighborhood Hits	357	Target Neighborhood Hits	584	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM5_HUMAN
NC score	0.597861 (rank : 49)	θ value	2.98157e-11 (rank : 46)
Query Neighborhood Hits	357	Target Neighborhood Hits	424	Shared Neighborhood Hits	213
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI39_HUMAN
NC score	0.596892 (rank : 50)	θ value	8.95645e-16 (rank : 19)
Query Neighborhood Hits	357	Target Neighborhood Hits	693	Shared Neighborhood Hits	254
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM4_HUMAN
NC score	0.596046 (rank : 51)	θ value	1.53129e-07 (rank : 81)
Query Neighborhood Hits	357	Target Neighborhood Hits	321	Shared Neighborhood Hits	203
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI22_HUMAN
NC score	0.595269 (rank : 52)	θ value	4.76016e-09 (rank : 68)
Query Neighborhood Hits	357	Target Neighborhood Hits	396	Shared Neighborhood Hits	216
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI39_MOUSE
NC score	0.594663 (rank : 53)	θ value	4.44505e-15 (rank : 25)
Query Neighborhood Hits	357	Target Neighborhood Hits	691	Shared Neighborhood Hits	257
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI25_MOUSE
NC score	0.593764 (rank : 54)	θ value	6.43352e-06 (rank : 100)
Query Neighborhood Hits	357	Target Neighborhood Hits	446	Shared Neighborhood Hits	221
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRIM7_HUMAN
NC score	0.586304 (rank : 55)	θ value	2.0648e-12 (rank : 37)
Query Neighborhood Hits	357	Target Neighborhood Hits	336	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI46_MOUSE
NC score	0.583832 (rank : 56)	θ value	9.29e-05 (rank : 104)
Query Neighborhood Hits	357	Target Neighborhood Hits	287	Shared Neighborhood Hits	177
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM6_MOUSE
NC score	0.582774 (rank : 57)	θ value	3.29651e-10 (rank : 53)
Query Neighborhood Hits	357	Target Neighborhood Hits	451	Shared Neighborhood Hits	212
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI46_HUMAN
NC score	0.582742 (rank : 58)	θ value	0.000602161 (rank : 116)
Query Neighborhood Hits	357	Target Neighborhood Hits	291	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM9_HUMAN
NC score	0.582412 (rank : 59)	θ value	3.08544e-08 (rank : 75)
Query Neighborhood Hits	357	Target Neighborhood Hits	294	Shared Neighborhood Hits	156
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM6_HUMAN
NC score	0.580431 (rank : 60)	θ value	9.59137e-10 (rank : 59)
Query Neighborhood Hits	357	Target Neighborhood Hits	412	Shared Neighborhood Hits	210
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI25_HUMAN
NC score	0.580404 (rank : 61)	θ value	3.77169e-06 (rank : 96)
Query Neighborhood Hits	357	Target Neighborhood Hits	472	Shared Neighborhood Hits	224
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI17_HUMAN
NC score	0.579531 (rank : 62)	θ value	7.34386e-10 (rank : 56)
Query Neighborhood Hits	357	Target Neighborhood Hits	318	Shared Neighborhood Hits	198
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI17_MOUSE
NC score	0.578948 (rank : 63)	θ value	1.06045e-08 (rank : 71)
Query Neighborhood Hits	357	Target Neighborhood Hits	620	Shared Neighborhood Hits	224
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI60_HUMAN
NC score	0.578336 (rank : 64)	θ value	1.80886e-08 (rank : 73)
Query Neighborhood Hits	357	Target Neighborhood Hits	357	Shared Neighborhood Hits	209
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM9_MOUSE
NC score	0.576661 (rank : 65)	θ value	5.26297e-08 (rank : 80)
Query Neighborhood Hits	357	Target Neighborhood Hits	274	Shared Neighborhood Hits	156
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI34_HUMAN
NC score	0.575338 (rank : 66)	θ value	5.26297e-08 (rank : 78)
Query Neighborhood Hits	357	Target Neighborhood Hits	416	Shared Neighborhood Hits	187
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI52_HUMAN
NC score	0.575139 (rank : 67)	θ value	0.21417 (rank : 213)
Query Neighborhood Hits	357	Target Neighborhood Hits	213	Shared Neighborhood Hits	171
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

RO52_HUMAN
NC score	0.574304 (rank : 68)	θ value	4.59992e-12 (rank : 38)
Query Neighborhood Hits	357	Target Neighborhood Hits	419	Shared Neighborhood Hits	231
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI27_HUMAN
NC score	0.573800 (rank : 69)	θ value	5.08577e-11 (rank : 48)
Query Neighborhood Hits	357	Target Neighborhood Hits	273	Shared Neighborhood Hits	192
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.571164 (rank : 70)	θ value	2.98157e-11 (rank : 43)
Query Neighborhood Hits	357	Target Neighborhood Hits	261	Shared Neighborhood Hits	187
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI47_HUMAN
NC score	0.568933 (rank : 71)	θ value	2.21117e-06 (rank : 93)
Query Neighborhood Hits	357	Target Neighborhood Hits	286	Shared Neighborhood Hits	186
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI11_HUMAN
NC score	0.567852 (rank : 72)	θ value	5.43371e-13 (rank : 33)
Query Neighborhood Hits	357	Target Neighborhood Hits	316	Shared Neighborhood Hits	207
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI43_HUMAN
NC score	0.567706 (rank : 73)	θ value	7.1131e-05 (rank : 103)
Query Neighborhood Hits	357	Target Neighborhood Hits	341	Shared Neighborhood Hits	202
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI68_MOUSE
NC score	0.567420 (rank : 74)	θ value	5.81887e-07 (rank : 83)
Query Neighborhood Hits	357	Target Neighborhood Hits	356	Shared Neighborhood Hits	212
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI15_HUMAN
NC score	0.566023 (rank : 75)	θ value	8.11959e-09 (rank : 70)
Query Neighborhood Hits	357	Target Neighborhood Hits	395	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI41_HUMAN
NC score	0.564424 (rank : 76)	θ value	4.0297e-08 (rank : 77)
Query Neighborhood Hits	357	Target Neighborhood Hits	349	Shared Neighborhood Hits	187
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI47_MOUSE
NC score	0.563869 (rank : 77)	θ value	0.00102713 (rank : 122)
Query Neighborhood Hits	357	Target Neighborhood Hits	295	Shared Neighborhood Hits	185
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI11_MOUSE
NC score	0.563385 (rank : 78)	θ value	1.63604e-09 (rank : 64)
Query Neighborhood Hits	357	Target Neighborhood Hits	329	Shared Neighborhood Hits	213
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

RO52_MOUSE
NC score	0.562401 (rank : 79)	θ value	1.63604e-09 (rank : 63)
Query Neighborhood Hits	357	Target Neighborhood Hits	360	Shared Neighborhood Hits	204
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI38_HUMAN
NC score	0.561622 (rank : 80)	θ value	2.13673e-09 (rank : 66)
Query Neighborhood Hits	357	Target Neighborhood Hits	373	Shared Neighborhood Hits	204
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TIF1B_HUMAN
NC score	0.557388 (rank : 81)	θ value	2.88119e-14 (rank : 27)
Query Neighborhood Hits	357	Target Neighborhood Hits	312	Shared Neighborhood Hits	123
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI68_HUMAN
NC score	0.557143 (rank : 82)	θ value	1.29631e-06 (rank : 90)
Query Neighborhood Hits	357	Target Neighborhood Hits	267	Shared Neighborhood Hits	189
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TIF1G_HUMAN
NC score	0.555681 (rank : 83)	θ value	5.60996e-18 (rank : 12)
Query Neighborhood Hits	357	Target Neighborhood Hits	410	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI60_MOUSE
NC score	0.555280 (rank : 84)	θ value	5.26297e-08 (rank : 79)
Query Neighborhood Hits	357	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TIF1B_MOUSE
NC score	0.550628 (rank : 85)	θ value	8.38298e-14 (rank : 29)
Query Neighborhood Hits	357	Target Neighborhood Hits	276	Shared Neighborhood Hits	122
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_MOUSE
NC score	0.548697 (rank : 86)	θ value	4.29542e-18 (rank : 11)
Query Neighborhood Hits	357	Target Neighborhood Hits	498	Shared Neighborhood Hits	134
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PML_HUMAN
NC score	0.548653 (rank : 87)	θ value	7.34386e-10 (rank : 55)
Query Neighborhood Hits	357	Target Neighborhood Hits	248	Shared Neighborhood Hits	122
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI34_MOUSE
NC score	0.543384 (rank : 88)	θ value	1.09739e-05 (rank : 101)
Query Neighborhood Hits	357	Target Neighborhood Hits	332	Shared Neighborhood Hits	166
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

PML_MOUSE
NC score	0.539250 (rank : 89)	θ value	4.76016e-09 (rank : 67)
Query Neighborhood Hits	357	Target Neighborhood Hits	246	Shared Neighborhood Hits	128
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI29_MOUSE
NC score	0.503989 (rank : 90)	θ value	4.45536e-07 (rank : 82)
Query Neighborhood Hits	357	Target Neighborhood Hits	306	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI49_HUMAN
NC score	0.502443 (rank : 91)	θ value	0.0193708 (rank : 155)
Query Neighborhood Hits	357	Target Neighborhood Hits	199	Shared Neighborhood Hits	154
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

ZN313_MOUSE
NC score	0.497651 (rank : 92)	θ value	9.29e-05 (rank : 105)
Query Neighborhood Hits	357	Target Neighborhood Hits	273	Shared Neighborhood Hits	186
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI42_MOUSE
NC score	0.495667 (rank : 93)	θ value	0.000461057 (rank : 115)
Query Neighborhood Hits	357	Target Neighborhood Hits	316	Shared Neighborhood Hits	129
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
NC score	0.493020 (rank : 94)	θ value	0.00869519 (rank : 143)
Query Neighborhood Hits	357	Target Neighborhood Hits	283	Shared Neighborhood Hits	123
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI29_HUMAN
NC score	0.492957 (rank : 95)	θ value	2.88788e-06 (rank : 95)
Query Neighborhood Hits	357	Target Neighborhood Hits	273	Shared Neighborhood Hits	112
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

ZN179_HUMAN
NC score	0.492091 (rank : 96)	θ value	0.00228821 (rank : 128)
Query Neighborhood Hits	357	Target Neighborhood Hits	178	Shared Neighborhood Hits	129
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

PEX10_HUMAN
NC score	0.489816 (rank : 97)	θ value	0.0113563 (rank : 145)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	191
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ZN313_HUMAN
NC score	0.488998 (rank : 98)	θ value	0.000158464 (rank : 107)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RN168_HUMAN
NC score	0.485327 (rank : 99)	θ value	0.00175202 (rank : 127)
Query Neighborhood Hits	357	Target Neighborhood Hits	370	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI48_HUMAN
NC score	0.483211 (rank : 100)	θ value	0.279714 (rank : 217)
Query Neighborhood Hits	357	Target Neighborhood Hits	192	Shared Neighborhood Hits	158
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI14_HUMAN
NC score	0.478363 (rank : 101)	θ value	0.00869519 (rank : 142)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	96
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TIF1A_HUMAN
NC score	0.476498 (rank : 102)	θ value	5.25075e-16 (rank : 17)
Query Neighborhood Hits	357	Target Neighborhood Hits	327	Shared Neighborhood Hits	121
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

RNF39_HUMAN
NC score	0.475374 (rank : 103)	θ value	0.365318 (rank : 226)
Query Neighborhood Hits	357	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RN168_MOUSE
NC score	0.472282 (rank : 104)	θ value	0.00298849 (rank : 132)
Query Neighborhood Hits	357	Target Neighborhood Hits	440	Shared Neighborhood Hits	191
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI14_MOUSE
NC score	0.471130 (rank : 105)	θ value	0.0148317 (rank : 150)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

MEFV_MOUSE
NC score	0.462729 (rank : 106)	θ value	0.0961366 (rank : 189)
Query Neighborhood Hits	357	Target Neighborhood Hits	236	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI16_MOUSE
NC score	0.456651 (rank : 107)	θ value	0.000270298 (rank : 111)
Query Neighborhood Hits	357	Target Neighborhood Hits	196	Shared Neighborhood Hits	98
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TIF1A_MOUSE
NC score	0.450158 (rank : 108)	θ value	1.99529e-15 (rank : 21)
Query Neighborhood Hits	357	Target Neighborhood Hits	307	Shared Neighborhood Hits	108
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

RN183_HUMAN
NC score	0.440858 (rank : 109)	θ value	0.00869519 (rank : 141)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	116
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

MEFV_HUMAN
NC score	0.440851 (rank : 110)	θ value	0.0563607 (rank : 174)
Query Neighborhood Hits	357	Target Neighborhood Hits	431	Shared Neighborhood Hits	119
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RN166_HUMAN
NC score	0.437689 (rank : 111)	θ value	0.0431538 (rank : 168)
Query Neighborhood Hits	357	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.433506 (rank : 112)	θ value	0.0431538 (rank : 169)
Query Neighborhood Hits	357	Target Neighborhood Hits	248	Shared Neighborhood Hits	169
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN125_MOUSE
NC score	0.430465 (rank : 113)	θ value	0.0193708 (rank : 153)
Query Neighborhood Hits	357	Target Neighborhood Hits	220	Shared Neighborhood Hits	161
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

NHLC1_MOUSE
NC score	0.429276 (rank : 114)	θ value	1.63604e-09 (rank : 62)
Query Neighborhood Hits	357	Target Neighborhood Hits	103	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN125_HUMAN
NC score	0.425992 (rank : 115)	θ value	0.0330416 (rank : 161)
Query Neighborhood Hits	357	Target Neighborhood Hits	230	Shared Neighborhood Hits	170
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

CHFR_HUMAN
NC score	0.424793 (rank : 116)	θ value	1.43324e-05 (rank : 102)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	181
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

BFAR_HUMAN
NC score	0.423699 (rank : 117)	θ value	0.0736092 (rank : 180)
Query Neighborhood Hits	357	Target Neighborhood Hits	222	Shared Neighborhood Hits	171
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

CHFR_MOUSE
NC score	0.421986 (rank : 118)	θ value	6.43352e-06 (rank : 99)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

BFAR_MOUSE
NC score	0.418170 (rank : 119)	θ value	0.0736092 (rank : 181)
Query Neighborhood Hits	357	Target Neighborhood Hits	232	Shared Neighborhood Hits	168
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RN183_MOUSE
NC score	0.415195 (rank : 120)	θ value	0.00390308 (rank : 134)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

NHLC1_HUMAN
NC score	0.407607 (rank : 121)	θ value	2.13673e-09 (rank : 65)
Query Neighborhood Hits	357	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

BRCA1_HUMAN
NC score	0.405053 (rank : 122)	θ value	0.163984 (rank : 198)
Query Neighborhood Hits	357	Target Neighborhood Hits	381	Shared Neighborhood Hits	184
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
NC score	0.397455 (rank : 123)	θ value	0.163984 (rank : 199)
Query Neighborhood Hits	357	Target Neighborhood Hits	436	Shared Neighborhood Hits	184
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RNF8_MOUSE
NC score	0.395705 (rank : 124)	θ value	0.279714 (rank : 216)
Query Neighborhood Hits	357	Target Neighborhood Hits	618	Shared Neighborhood Hits	241
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI16_HUMAN
NC score	0.393348 (rank : 125)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	357	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

RNF8_HUMAN
NC score	0.385323 (rank : 126)	θ value	0.163984 (rank : 204)
Query Neighborhood Hits	357	Target Neighborhood Hits	622	Shared Neighborhood Hits	238
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RN141_MOUSE
NC score	0.381017 (rank : 127)	θ value	0.00869519 (rank : 140)
Query Neighborhood Hits	357	Target Neighborhood Hits	200	Shared Neighborhood Hits	169
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.380232 (rank : 128)	θ value	0.00869519 (rank : 139)
Query Neighborhood Hits	357	Target Neighborhood Hits	199	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN152_MOUSE
NC score	0.377817 (rank : 129)	θ value	0.00020696 (rank : 109)
Query Neighborhood Hits	357	Target Neighborhood Hits	109	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRI44_MOUSE
NC score	0.374928 (rank : 130)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	357	Target Neighborhood Hits	327	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

RING1_HUMAN
NC score	0.374384 (rank : 131)	θ value	0.21417 (rank : 208)
Query Neighborhood Hits	357	Target Neighborhood Hits	219	Shared Neighborhood Hits	153
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RN152_HUMAN
NC score	0.374325 (rank : 132)	θ value	0.000158464 (rank : 106)
Query Neighborhood Hits	357	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TRI44_HUMAN
NC score	0.369801 (rank : 133)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	357	Target Neighborhood Hits	393	Shared Neighborhood Hits	104
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

RING1_MOUSE
NC score	0.368055 (rank : 134)	θ value	0.21417 (rank : 209)
Query Neighborhood Hits	357	Target Neighborhood Hits	220	Shared Neighborhood Hits	153
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RAD18_MOUSE
NC score	0.366741 (rank : 135)	θ value	0.00390308 (rank : 133)
Query Neighborhood Hits	357	Target Neighborhood Hits	230	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN185_HUMAN
NC score	0.363666 (rank : 136)	θ value	0.0563607 (rank : 178)
Query Neighborhood Hits	357	Target Neighborhood Hits	213	Shared Neighborhood Hits	162
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.361909 (rank : 137)	θ value	0.0563607 (rank : 179)
Query Neighborhood Hits	357	Target Neighborhood Hits	211	Shared Neighborhood Hits	160
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RAD18_HUMAN
NC score	0.358212 (rank : 138)	θ value	0.00134147 (rank : 125)
Query Neighborhood Hits	357	Target Neighborhood Hits	284	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RNF5_HUMAN
NC score	0.355317 (rank : 139)	θ value	0.0736092 (rank : 186)
Query Neighborhood Hits	357	Target Neighborhood Hits	206	Shared Neighborhood Hits	156
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.352465 (rank : 140)	θ value	0.0961366 (rank : 191)
Query Neighborhood Hits	357	Target Neighborhood Hits	206	Shared Neighborhood Hits	156
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RING2_MOUSE
NC score	0.347265 (rank : 141)	θ value	0.365318 (rank : 222)
Query Neighborhood Hits	357	Target Neighborhood Hits	199	Shared Neighborhood Hits	149
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

BSPRY_MOUSE
NC score	0.347103 (rank : 142)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RING2_HUMAN
NC score	0.346512 (rank : 143)	θ value	0.365318 (rank : 221)
Query Neighborhood Hits	357	Target Neighborhood Hits	201	Shared Neighborhood Hits	149
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RFPL3_HUMAN
NC score	0.343215 (rank : 144)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	99
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

BSPRY_HUMAN
NC score	0.340415 (rank : 145)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	357	Target Neighborhood Hits	115	Shared Neighborhood Hits	78
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RN146_HUMAN
NC score	0.338996 (rank : 146)	θ value	0.0563607 (rank : 176)
Query Neighborhood Hits	357	Target Neighborhood Hits	162	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RFPL2_HUMAN
NC score	0.337499 (rank : 147)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RN146_MOUSE
NC score	0.336963 (rank : 148)	θ value	0.0563607 (rank : 177)
Query Neighborhood Hits	357	Target Neighborhood Hits	161	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI66_MOUSE
NC score	0.334866 (rank : 149)	θ value	9.92553e-07 (rank : 85)
Query Neighborhood Hits	357	Target Neighborhood Hits	491	Shared Neighborhood Hits	81
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RFPL1_HUMAN
NC score	0.334279 (rank : 150)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

ERMAP_HUMAN
NC score	0.332376 (rank : 151)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI66_HUMAN
NC score	0.330969 (rank : 152)	θ value	1.29631e-06 (rank : 89)
Query Neighborhood Hits	357	Target Neighborhood Hits	479	Shared Neighborhood Hits	76
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RNF41_HUMAN
NC score	0.313415 (rank : 153)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	357	Target Neighborhood Hits	226	Shared Neighborhood Hits	169
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.313018 (rank : 154)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	357	Target Neighborhood Hits	224	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

ERMAP_MOUSE
NC score	0.305958 (rank : 155)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	357	Target Neighborhood Hits	231	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

DTX3_MOUSE
NC score	0.301224 (rank : 156)	θ value	0.125558 (rank : 193)
Query Neighborhood Hits	357	Target Neighborhood Hits	202	Shared Neighborhood Hits	156
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

FSD1L_MOUSE
NC score	0.300873 (rank : 157)	θ value	0.00298849 (rank : 130)
Query Neighborhood Hits	357	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

SPRY4_MOUSE
NC score	0.298278 (rank : 158)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	357	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

RNF4_HUMAN
NC score	0.297673 (rank : 159)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	357	Target Neighborhood Hits	212	Shared Neighborhood Hits	160
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RN169_HUMAN
NC score	0.297197 (rank : 160)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	357	Target Neighborhood Hits	203	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

BT1A1_MOUSE
NC score	0.295725 (rank : 161)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	357	Target Neighborhood Hits	252	Shared Neighborhood Hits	62
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

DTX3_HUMAN
NC score	0.294994 (rank : 162)	θ value	0.163984 (rank : 202)
Query Neighborhood Hits	357	Target Neighborhood Hits	198	Shared Neighborhood Hits	152
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

UHRF2_HUMAN
NC score	0.292985 (rank : 163)	θ value	0.00869519 (rank : 144)
Query Neighborhood Hits	357	Target Neighborhood Hits	269	Shared Neighborhood Hits	155
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RNF4_MOUSE
NC score	0.292541 (rank : 164)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	357	Target Neighborhood Hits	212	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

BT3A3_HUMAN
NC score	0.291548 (rank : 165)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	357	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT1A1_HUMAN
NC score	0.291218 (rank : 166)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	357	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

SPRY4_HUMAN
NC score	0.290327 (rank : 167)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	357	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BT2A2_HUMAN
NC score	0.288815 (rank : 168)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	357	Target Neighborhood Hits	191	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT3A1_HUMAN
NC score	0.288540 (rank : 169)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	357	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TOPRS_MOUSE
NC score	0.287947 (rank : 170)	θ value	0.00390308 (rank : 136)
Query Neighborhood Hits	357	Target Neighborhood Hits	263	Shared Neighborhood Hits	145
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BTNL9_HUMAN
NC score	0.287623 (rank : 171)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	357	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

UHRF2_MOUSE
NC score	0.287389 (rank : 172)	θ value	0.0148317 (rank : 151)
Query Neighborhood Hits	357	Target Neighborhood Hits	275	Shared Neighborhood Hits	151
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ARD1_MOUSE
NC score	0.284500 (rank : 173)	θ value	1.74796e-11 (rank : 41)
Query Neighborhood Hits	357	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

BTNL3_HUMAN
NC score	0.284037 (rank : 174)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TOPRS_HUMAN
NC score	0.283452 (rank : 175)	θ value	0.00390308 (rank : 135)
Query Neighborhood Hits	357	Target Neighborhood Hits	286	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

R113B_HUMAN
NC score	0.278889 (rank : 176)	θ value	0.21417 (rank : 207)
Query Neighborhood Hits	357	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

BT2A1_HUMAN
NC score	0.278764 (rank : 177)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	357	Target Neighborhood Hits	185	Shared Neighborhood Hits	60
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

SMRA3_HUMAN
NC score	0.278538 (rank : 178)	θ value	0.00102713 (rank : 121)
Query Neighborhood Hits	357	Target Neighborhood Hits	265	Shared Neighborhood Hits	176
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ARD1_HUMAN
NC score	0.277436 (rank : 179)	θ value	5.43371e-13 (rank : 32)
Query Neighborhood Hits	357	Target Neighborhood Hits	621	Shared Neighborhood Hits	89
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

BT2A3_HUMAN
NC score	0.277024 (rank : 180)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	357	Target Neighborhood Hits	195	Shared Neighborhood Hits	57
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

AMFR2_HUMAN
NC score	0.273144 (rank : 181)	θ value	0.00298849 (rank : 129)
Query Neighborhood Hits	357	Target Neighborhood Hits	219	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

BTNL8_HUMAN
NC score	0.272595 (rank : 182)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

AMFR_MOUSE
NC score	0.269529 (rank : 183)	θ value	0.00509761 (rank : 137)
Query Neighborhood Hits	357	Target Neighborhood Hits	208	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

SMRA3_MOUSE
NC score	0.268715 (rank : 184)	θ value	0.000786445 (rank : 118)
Query Neighborhood Hits	357	Target Neighborhood Hits	267	Shared Neighborhood Hits	175
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

FSD1L_HUMAN
NC score	0.265386 (rank : 185)	θ value	0.0148317 (rank : 147)
Query Neighborhood Hits	357	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

R113A_HUMAN
NC score	0.261150 (rank : 186)	θ value	0.125558 (rank : 196)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	125
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RAG1_HUMAN
NC score	0.259163 (rank : 187)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	357	Target Neighborhood Hits	203	Shared Neighborhood Hits	134
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

LNX2_HUMAN
NC score	0.257483 (rank : 188)	θ value	0.000461057 (rank : 113)
Query Neighborhood Hits	357	Target Neighborhood Hits	389	Shared Neighborhood Hits	176
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.256548 (rank : 189)	θ value	0.000270298 (rank : 110)
Query Neighborhood Hits	357	Target Neighborhood Hits	407	Shared Neighborhood Hits	176
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

CBLC_MOUSE
NC score	0.251782 (rank : 190)	θ value	0.00134147 (rank : 123)
Query Neighborhood Hits	357	Target Neighborhood Hits	186	Shared Neighborhood Hits	132
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CM007_MOUSE
NC score	0.251547 (rank : 191)	θ value	0.365318 (rank : 218)
Query Neighborhood Hits	357	Target Neighborhood Hits	416	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RAG1_MOUSE
NC score	0.249492 (rank : 192)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	357	Target Neighborhood Hits	189	Shared Neighborhood Hits	134
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

LNX1_MOUSE
NC score	0.249273 (rank : 193)	θ value	0.000786445 (rank : 117)
Query Neighborhood Hits	357	Target Neighborhood Hits	377	Shared Neighborhood Hits	164
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.247357 (rank : 194)	θ value	0.00175202 (rank : 126)
Query Neighborhood Hits	357	Target Neighborhood Hits	379	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

CBLC_HUMAN
NC score	0.247302 (rank : 195)	θ value	0.00869519 (rank : 138)
Query Neighborhood Hits	357	Target Neighborhood Hits	173	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

RFWD2_HUMAN
NC score	0.246663 (rank : 196)	θ value	0.47712 (rank : 235)
Query Neighborhood Hits	357	Target Neighborhood Hits	518	Shared Neighborhood Hits	191
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.246115 (rank : 197)	θ value	0.47712 (rank : 236)
Query Neighborhood Hits	357	Target Neighborhood Hits	535	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRAF6_MOUSE
NC score	0.241632 (rank : 198)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	162
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

BIRC7_HUMAN
NC score	0.239255 (rank : 199)	θ value	0.62314 (rank : 238)
Query Neighborhood Hits	357	Target Neighborhood Hits	185	Shared Neighborhood Hits	135
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

TRAF6_HUMAN
NC score	0.238130 (rank : 200)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	357	Target Neighborhood Hits	267	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

UHRF1_HUMAN
NC score	0.234772 (rank : 201)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	357	Target Neighborhood Hits	272	Shared Neighborhood Hits	149
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
NC score	0.234474 (rank : 202)	θ value	1.38821 (rank : 268)
Query Neighborhood Hits	357	Target Neighborhood Hits	278	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CBL_HUMAN
NC score	0.224891 (rank : 203)	θ value	0.0563607 (rank : 171)
Query Neighborhood Hits	357	Target Neighborhood Hits	353	Shared Neighborhood Hits	147
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CM007_HUMAN
NC score	0.224472 (rank : 204)	θ value	0.813845 (rank : 248)
Query Neighborhood Hits	357	Target Neighborhood Hits	422	Shared Neighborhood Hits	161
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

RN167_MOUSE
NC score	0.221462 (rank : 205)	θ value	0.00102713 (rank : 119)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	99
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_HUMAN
NC score	0.220605 (rank : 206)	θ value	0.000461057 (rank : 114)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

CBL_MOUSE
NC score	0.220068 (rank : 207)	θ value	0.0563607 (rank : 172)
Query Neighborhood Hits	357	Target Neighborhood Hits	426	Shared Neighborhood Hits	151
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

DTX3L_HUMAN
NC score	0.218746 (rank : 208)	θ value	0.0252991 (rank : 156)
Query Neighborhood Hits	357	Target Neighborhood Hits	187	Shared Neighborhood Hits	131
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

CBLB_MOUSE
NC score	0.216788 (rank : 209)	θ value	0.163984 (rank : 201)
Query Neighborhood Hits	357	Target Neighborhood Hits	277	Shared Neighborhood Hits	142
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.216462 (rank : 210)	θ value	0.163984 (rank : 200)
Query Neighborhood Hits	357	Target Neighborhood Hits	261	Shared Neighborhood Hits	140
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

AMD_HUMAN
NC score	0.213956 (rank : 211)	θ value	4.0297e-08 (rank : 76)
Query Neighborhood Hits	357	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	P19021, O95080, Q16252, Q16253, Q86U53, Q8WVC7, Q9UCG0	Gene names	PAM
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

RNF13_MOUSE
NC score	0.213157 (rank : 212)	θ value	0.00102713 (rank : 120)
Query Neighborhood Hits	357	Target Neighborhood Hits	164	Shared Neighborhood Hits	96
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
NC score	0.211776 (rank : 213)	θ value	0.00035302 (rank : 112)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

PCGF6_MOUSE
NC score	0.211042 (rank : 214)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	122
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_HUMAN
NC score	0.209008 (rank : 215)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	357	Target Neighborhood Hits	178	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF4_HUMAN
NC score	0.196278 (rank : 216)	θ value	0.47712 (rank : 233)
Query Neighborhood Hits	357	Target Neighborhood Hits	161	Shared Neighborhood Hits	122
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.195975 (rank : 217)	θ value	0.47712 (rank : 234)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	120
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF2_HUMAN
NC score	0.195062 (rank : 218)	θ value	0.47712 (rank : 231)
Query Neighborhood Hits	357	Target Neighborhood Hits	222	Shared Neighborhood Hits	118
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.194685 (rank : 219)	θ value	0.47712 (rank : 232)
Query Neighborhood Hits	357	Target Neighborhood Hits	213	Shared Neighborhood Hits	117
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

RN122_HUMAN
NC score	0.191104 (rank : 220)	θ value	0.365318 (rank : 223)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

AMD_MOUSE
NC score	0.188588 (rank : 221)	θ value	0.00020696 (rank : 108)
Query Neighborhood Hits	357	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P97467	Gene names	Pam
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

RN165_HUMAN
NC score	0.187530 (rank : 222)	θ value	0.365318 (rank : 224)
Query Neighborhood Hits	357	Target Neighborhood Hits	151	Shared Neighborhood Hits	94
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

PZRN3_MOUSE
NC score	0.184172 (rank : 223)	θ value	0.62314 (rank : 242)
Query Neighborhood Hits	357	Target Neighborhood Hits	447	Shared Neighborhood Hits	172
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.180995 (rank : 224)	θ value	1.81305 (rank : 274)
Query Neighborhood Hits	357	Target Neighborhood Hits	461	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF5_MOUSE
NC score	0.180324 (rank : 225)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	357	Target Neighborhood Hits	355	Shared Neighborhood Hits	152
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RN122_MOUSE
NC score	0.180251 (rank : 226)	θ value	0.813845 (rank : 254)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RBBP6_MOUSE
NC score	0.178353 (rank : 227)	θ value	0.0431538 (rank : 167)
Query Neighborhood Hits	357	Target Neighborhood Hits	1014	Shared Neighborhood Hits	139
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRAF7_HUMAN
NC score	0.175101 (rank : 228)	θ value	0.0113563 (rank : 146)
Query Neighborhood Hits	357	Target Neighborhood Hits	482	Shared Neighborhood Hits	156
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

GOLI_MOUSE
NC score	0.174736 (rank : 229)	θ value	0.125558 (rank : 195)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
NC score	0.174546 (rank : 230)	θ value	0.163984 (rank : 203)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

TRAF7_MOUSE
NC score	0.172141 (rank : 231)	θ value	0.0252991 (rank : 157)
Query Neighborhood Hits	357	Target Neighborhood Hits	470	Shared Neighborhood Hits	151
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

PZRN4_HUMAN
NC score	0.170602 (rank : 232)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	357	Target Neighborhood Hits	438	Shared Neighborhood Hits	174
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

FLNC_HUMAN
NC score	0.167837 (rank : 233)	θ value	1.38499e-08 (rank : 72)
Query Neighborhood Hits	357	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

TRAF4_HUMAN
NC score	0.165162 (rank : 234)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	357	Target Neighborhood Hits	373	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

FLNA_MOUSE
NC score	0.164963 (rank : 235)	θ value	1.29631e-06 (rank : 88)
Query Neighborhood Hits	357	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_HUMAN
NC score	0.164896 (rank : 236)	θ value	1.29631e-06 (rank : 87)
Query Neighborhood Hits	357	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

RC3H1_MOUSE
NC score	0.164680 (rank : 237)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	357	Target Neighborhood Hits	244	Shared Neighborhood Hits	119
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RBBP6_HUMAN
NC score	0.161386 (rank : 238)	θ value	0.0431538 (rank : 166)
Query Neighborhood Hits	357	Target Neighborhood Hits	1135	Shared Neighborhood Hits	139
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FLNB_HUMAN
NC score	0.161325 (rank : 239)	θ value	2.21117e-06 (rank : 92)
Query Neighborhood Hits	357	Target Neighborhood Hits	111	Shared Neighborhood Hits	15
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

FLNB_MOUSE
NC score	0.161259 (rank : 240)	θ value	2.88788e-06 (rank : 94)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

UB7I3_MOUSE
NC score	0.160923 (rank : 241)	θ value	0.125558 (rank : 197)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RC3H1_HUMAN
NC score	0.157442 (rank : 242)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	357	Target Neighborhood Hits	433	Shared Neighborhood Hits	124
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TRAF5_HUMAN
NC score	0.151586 (rank : 243)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	357	Target Neighborhood Hits	396	Shared Neighborhood Hits	142
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

RNF24_MOUSE
NC score	0.149959 (rank : 244)	θ value	2.36792 (rank : 283)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF38_HUMAN
NC score	0.149358 (rank : 245)	θ value	0.21417 (rank : 210)
Query Neighborhood Hits	357	Target Neighborhood Hits	155	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF6_HUMAN
NC score	0.148980 (rank : 246)	θ value	0.0431538 (rank : 170)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF12_MOUSE
NC score	0.148842 (rank : 247)	θ value	0.365318 (rank : 225)
Query Neighborhood Hits	357	Target Neighborhood Hits	159	Shared Neighborhood Hits	78
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RN133_HUMAN
NC score	0.148449 (rank : 248)	θ value	0.62314 (rank : 243)
Query Neighborhood Hits	357	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF24_HUMAN
NC score	0.146841 (rank : 249)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

ZSWM2_MOUSE
NC score	0.146039 (rank : 250)	θ value	0.365318 (rank : 228)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RNF32_HUMAN
NC score	0.142439 (rank : 251)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	357	Target Neighborhood Hits	133	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

DZIP3_HUMAN
NC score	0.142249 (rank : 252)	θ value	0.125558 (rank : 194)
Query Neighborhood Hits	357	Target Neighborhood Hits	399	Shared Neighborhood Hits	116
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
NC score	0.140723 (rank : 253)	θ value	0.47712 (rank : 229)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	123
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

RNF38_MOUSE
NC score	0.140277 (rank : 254)	θ value	0.62314 (rank : 244)
Query Neighborhood Hits	357	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF12_HUMAN
NC score	0.138943 (rank : 255)	θ value	0.813845 (rank : 256)
Query Neighborhood Hits	357	Target Neighborhood Hits	173	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

TRAF2_HUMAN
NC score	0.138891 (rank : 256)	θ value	0.813845 (rank : 257)
Query Neighborhood Hits	357	Target Neighborhood Hits	402	Shared Neighborhood Hits	123
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

ZN364_HUMAN
NC score	0.137781 (rank : 257)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RN139_MOUSE
NC score	0.137119 (rank : 258)	θ value	0.0736092 (rank : 185)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RAPSN_MOUSE
NC score	0.136835 (rank : 259)	θ value	0.0431538 (rank : 165)
Query Neighborhood Hits	357	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

ZSWM2_HUMAN
NC score	0.135989 (rank : 260)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	357	Target Neighborhood Hits	151	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN126_MOUSE
NC score	0.135767 (rank : 261)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

MNAB_HUMAN
NC score	0.135601 (rank : 262)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	357	Target Neighborhood Hits	196	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

TRAF2_MOUSE
NC score	0.135577 (rank : 263)	θ value	1.06291 (rank : 263)
Query Neighborhood Hits	357	Target Neighborhood Hits	394	Shared Neighborhood Hits	126
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

UB7I3_HUMAN
NC score	0.135090 (rank : 264)	θ value	0.813845 (rank : 258)
Query Neighborhood Hits	357	Target Neighborhood Hits	136	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

MNAB_MOUSE
NC score	0.134924 (rank : 265)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	357	Target Neighborhood Hits	231	Shared Neighborhood Hits	105
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RAPSN_HUMAN
NC score	0.130688 (rank : 266)	θ value	0.0961366 (rank : 190)
Query Neighborhood Hits	357	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

ZN364_MOUSE
NC score	0.130286 (rank : 267)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RNF19_MOUSE
NC score	0.129590 (rank : 268)	θ value	0.0148317 (rank : 149)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

TRAF3_MOUSE
NC score	0.129442 (rank : 269)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	357	Target Neighborhood Hits	476	Shared Neighborhood Hits	159
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RNF19_HUMAN
NC score	0.129380 (rank : 270)	θ value	0.0148317 (rank : 148)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF26_HUMAN
NC score	0.129378 (rank : 271)	θ value	1.81305 (rank : 275)
Query Neighborhood Hits	357	Target Neighborhood Hits	95	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

TRAIP_HUMAN
NC score	0.126454 (rank : 272)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	357	Target Neighborhood Hits	780	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.124472 (rank : 273)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	357	Target Neighborhood Hits	745	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RN126_HUMAN
NC score	0.123722 (rank : 274)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN139_HUMAN
NC score	0.123614 (rank : 275)	θ value	0.813845 (rank : 255)
Query Neighborhood Hits	357	Target Neighborhood Hits	130	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

PJA1_HUMAN
NC score	0.122961 (rank : 276)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	357	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

TRAF3_HUMAN
NC score	0.120132 (rank : 277)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	357	Target Neighborhood Hits	463	Shared Neighborhood Hits	152
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

MGRN1_HUMAN
NC score	0.118621 (rank : 278)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	357	Target Neighborhood Hits	192	Shared Neighborhood Hits	100
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
NC score	0.116702 (rank : 279)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	357	Target Neighborhood Hits	149	Shared Neighborhood Hits	97
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

PJA1_MOUSE
NC score	0.115346 (rank : 280)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	357	Target Neighborhood Hits	145	Shared Neighborhood Hits	84
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

MKRN4_HUMAN
NC score	0.114817 (rank : 281)	θ value	0.62314 (rank : 240)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MKRN3_HUMAN
NC score	0.114233 (rank : 282)	θ value	0.813845 (rank : 250)
Query Neighborhood Hits	357	Target Neighborhood Hits	165	Shared Neighborhood Hits	84
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RNF32_MOUSE
NC score	0.112675 (rank : 283)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	357	Target Neighborhood Hits	129	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

BIRC8_HUMAN
NC score	0.110105 (rank : 284)	θ value	0.813845 (rank : 246)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

RN103_HUMAN
NC score	0.104807 (rank : 285)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	357	Target Neighborhood Hits	153	Shared Neighborhood Hits	88
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
NC score	0.104441 (rank : 286)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RKHD1_HUMAN
NC score	0.101579 (rank : 287)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	69
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF11_HUMAN
NC score	0.100868 (rank : 288)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	357	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.100384 (rank : 289)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	357	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF14_MOUSE
NC score	0.099322 (rank : 290)	θ value	0.0330416 (rank : 162)
Query Neighborhood Hits	357	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

MKRN3_MOUSE
NC score	0.098937 (rank : 291)	θ value	2.36792 (rank : 282)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

TRAF4_MOUSE
NC score	0.095657 (rank : 292)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	357	Target Neighborhood Hits	338	Shared Neighborhood Hits	102
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

BRE1B_MOUSE
NC score	0.094986 (rank : 293)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	357	Target Neighborhood Hits	970	Shared Neighborhood Hits	203
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MKRN2_MOUSE
NC score	0.093739 (rank : 294)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	357	Target Neighborhood Hits	130	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN1_HUMAN
NC score	0.093721 (rank : 295)	θ value	2.36792 (rank : 280)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

LY10_HUMAN
NC score	0.093674 (rank : 296)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	357	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MKRN1_MOUSE
NC score	0.092788 (rank : 297)	θ value	2.36792 (rank : 281)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

BRE1B_HUMAN
NC score	0.092535 (rank : 298)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	357	Target Neighborhood Hits	1040	Shared Neighborhood Hits	201
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BARD1_HUMAN
NC score	0.091054 (rank : 299)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	357	Target Neighborhood Hits	427	Shared Neighborhood Hits	91
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MKRN2_HUMAN
NC score	0.089454 (rank : 300)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	357	Target Neighborhood Hits	129	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

BRAP_HUMAN
NC score	0.088970 (rank : 301)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	357	Target Neighborhood Hits	560	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RNF14_HUMAN
NC score	0.087735 (rank : 302)	θ value	0.0193708 (rank : 154)
Query Neighborhood Hits	357	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

FA55D_HUMAN
NC score	0.087275 (rank : 303)	θ value	0.279714 (rank : 214)
Query Neighborhood Hits	357	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UWF7, Q6QDB4, Q9NXP5	Gene names	FAM55D, C11orf33
Domain Architecture	No domain graphic available
Description	Protein FAM55D precursor.

RNF34_MOUSE
NC score	0.085921 (rank : 304)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	357	Target Neighborhood Hits	160	Shared Neighborhood Hits	83
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

ZN363_MOUSE
NC score	0.085408 (rank : 305)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

BRAP_MOUSE
NC score	0.084790 (rank : 306)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	357	Target Neighborhood Hits	409	Shared Neighborhood Hits	111
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

ZN363_HUMAN
NC score	0.084176 (rank : 307)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	357	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RNF34_HUMAN
NC score	0.084145 (rank : 308)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	357	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

BARD1_MOUSE
NC score	0.082234 (rank : 309)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	357	Target Neighborhood Hits	411	Shared Neighborhood Hits	87
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

SIAH2_HUMAN
NC score	0.079800 (rank : 310)	θ value	0.21417 (rank : 211)
Query Neighborhood Hits	357	Target Neighborhood Hits	94	Shared Neighborhood Hits	50
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

RN123_MOUSE
NC score	0.079179 (rank : 311)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	115
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BIRC3_HUMAN
NC score	0.078508 (rank : 312)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	357	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

SIAH2_MOUSE
NC score	0.078232 (rank : 313)	θ value	0.21417 (rank : 212)
Query Neighborhood Hits	357	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

RN123_HUMAN
NC score	0.077904 (rank : 314)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	357	Target Neighborhood Hits	175	Shared Neighborhood Hits	113
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

AIRE_HUMAN
NC score	0.077223 (rank : 315)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	357	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

BIRC2_MOUSE
NC score	0.077086 (rank : 316)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

IBRD3_HUMAN
NC score	0.076606 (rank : 317)	θ value	1.06291 (rank : 259)
Query Neighborhood Hits	357	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

AIRE_MOUSE
NC score	0.076068 (rank : 318)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	357	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MAT1_HUMAN
NC score	0.073697 (rank : 319)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	357	Target Neighborhood Hits	179	Shared Neighborhood Hits	53
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
NC score	0.073576 (rank : 320)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	357	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

BIRC2_HUMAN
NC score	0.072883 (rank : 321)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	357	Target Neighborhood Hits	142	Shared Neighborhood Hits	80
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BRE1A_HUMAN
NC score	0.071394 (rank : 322)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	357	Target Neighborhood Hits	1071	Shared Neighborhood Hits	182
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

SP110_HUMAN
NC score	0.069827 (rank : 323)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

CNOT4_HUMAN
NC score	0.068262 (rank : 324)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	357	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BRE1A_MOUSE
NC score	0.068148 (rank : 325)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	357	Target Neighborhood Hits	1025	Shared Neighborhood Hits	176
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

APC11_MOUSE
NC score	0.067353 (rank : 326)	θ value	1.81305 (rank : 270)
Query Neighborhood Hits	357	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

BIRC3_MOUSE
NC score	0.067245 (rank : 327)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	357	Target Neighborhood Hits	113	Shared Neighborhood Hits	68
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

PF21A_MOUSE
NC score	0.067025 (rank : 328)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	357	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

TTC3_HUMAN
NC score	0.066894 (rank : 329)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	357	Target Neighborhood Hits	664	Shared Neighborhood Hits	112
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

PF21A_HUMAN
NC score	0.066214 (rank : 330)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	357	Target Neighborhood Hits	303	Shared Neighborhood Hits	30
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

IBRD2_HUMAN
NC score	0.066098 (rank : 331)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	357	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

RNF37_MOUSE
NC score	0.065486 (rank : 332)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

IBRD2_MOUSE
NC score	0.065162 (rank : 333)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	357	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

EXOC3_MOUSE
NC score	0.064668 (rank : 334)	θ value	0.0330416 (rank : 159)
Query Neighborhood Hits	357	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

CNOT4_MOUSE
NC score	0.064603 (rank : 335)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	357	Target Neighborhood Hits	277	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

EXOC3_HUMAN
NC score	0.064301 (rank : 336)	θ value	0.0330416 (rank : 158)
Query Neighborhood Hits	357	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

ARI2_HUMAN
NC score	0.063952 (rank : 337)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	357	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

APC11_HUMAN
NC score	0.063707 (rank : 338)	θ value	1.81305 (rank : 269)
Query Neighborhood Hits	357	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

PKCB1_HUMAN
NC score	0.063663 (rank : 339)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	357	Target Neighborhood Hits	488	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

ARI2_MOUSE
NC score	0.063218 (rank : 340)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

BAZ2A_HUMAN
NC score	0.062847 (rank : 341)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	357	Target Neighborhood Hits	780	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MYLIP_HUMAN
NC score	0.061799 (rank : 342)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	357	Target Neighborhood Hits	162	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NEUL1_HUMAN
NC score	0.060538 (rank : 343)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

GOGB1_HUMAN
NC score	0.060479 (rank : 344)	θ value	0.0736092 (rank : 182)
Query Neighborhood Hits	357	Target Neighborhood Hits	2297	Shared Neighborhood Hits	149
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CROCC_MOUSE
NC score	0.060083 (rank : 345)	θ value	0.00134147 (rank : 124)
Query Neighborhood Hits	357	Target Neighborhood Hits	1460	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

BAZ2B_HUMAN
NC score	0.060012 (rank : 346)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	357	Target Neighborhood Hits	803	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

RFFL_HUMAN
NC score	0.059692 (rank : 347)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	357	Target Neighborhood Hits	175	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

BAZ2A_MOUSE
NC score	0.059683 (rank : 348)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	357	Target Neighborhood Hits	744	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

SYNE1_HUMAN
NC score	0.059326 (rank : 349)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	357	Target Neighborhood Hits	1484	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

NEURL_MOUSE
NC score	0.058584 (rank : 350)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

CP250_MOUSE
NC score	0.058509 (rank : 351)	θ value	1.81305 (rank : 271)
Query Neighborhood Hits	357	Target Neighborhood Hits	1583	Shared Neighborhood Hits	125
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CP250_HUMAN
NC score	0.058356 (rank : 352)	θ value	0.125558 (rank : 192)
Query Neighborhood Hits	357	Target Neighborhood Hits	1805	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

PCNT_HUMAN
NC score	0.058013 (rank : 353)	θ value	0.0431538 (rank : 164)
Query Neighborhood Hits	357	Target Neighborhood Hits	1551	Shared Neighborhood Hits	108
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

NEMO_MOUSE
NC score	0.056939 (rank : 354)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	357	Target Neighborhood Hits	658	Shared Neighborhood Hits	71
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

BPTF_HUMAN
NC score	0.056933 (rank : 355)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	357	Target Neighborhood Hits	786	Shared Neighborhood Hits	45
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

GOGA4_MOUSE
NC score	0.056516 (rank : 356)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	357	Target Neighborhood Hits	1939	Shared Neighborhood Hits	136
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RFFL_MOUSE
NC score	0.056277 (rank : 357)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	357	Target Neighborhood Hits	145	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

LRSM1_HUMAN
NC score	0.056010 (rank : 358)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	357	Target Neighborhood Hits	1078	Shared Neighborhood Hits	136
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PHF12_MOUSE
NC score	0.055986 (rank : 359)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	357	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.055415 (rank : 360)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CE290_HUMAN
NC score	0.055073 (rank : 361)	θ value	0.62314 (rank : 239)
Query Neighborhood Hits	357	Target Neighborhood Hits	1553	Shared Neighborhood Hits	119
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CROCC_HUMAN
NC score	0.054820 (rank : 362)	θ value	0.21417 (rank : 205)
Query Neighborhood Hits	357	Target Neighborhood Hits	1409	Shared Neighborhood Hits	112
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

BAZ1A_HUMAN
NC score	0.054812 (rank : 363)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	357	Target Neighborhood Hits	693	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PLEC1_HUMAN
NC score	0.054753 (rank : 364)	θ value	0.0563607 (rank : 175)
Query Neighborhood Hits	357	Target Neighborhood Hits	1326	Shared Neighborhood Hits	103
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

LRSM1_MOUSE
NC score	0.053920 (rank : 365)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	357	Target Neighborhood Hits	874	Shared Neighborhood Hits	127
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

CENPF_HUMAN
NC score	0.052096 (rank : 366)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	357	Target Neighborhood Hits	1932	Shared Neighborhood Hits	141
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MIB1_MOUSE
NC score	0.051859 (rank : 367)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	357	Target Neighborhood Hits	471	Shared Neighborhood Hits	95
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RN175_HUMAN
NC score	0.051770 (rank : 368)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	357	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

MIB1_HUMAN
NC score	0.051630 (rank : 369)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	357	Target Neighborhood Hits	470	Shared Neighborhood Hits	96
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

GOGA3_MOUSE
NC score	0.051107 (rank : 370)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	357	Target Neighborhood Hits	1437	Shared Neighborhood Hits	114
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SIA1B_MOUSE
NC score	0.051050 (rank : 371)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	357	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

RBX2_MOUSE
NC score	0.050894 (rank : 372)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	357	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

PF21B_HUMAN
NC score	0.050798 (rank : 373)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RBX2_HUMAN
NC score	0.050763 (rank : 374)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	357	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

BAZ1B_MOUSE
NC score	0.050623 (rank : 375)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	357	Target Neighborhood Hits	394	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

VPS36_HUMAN
NC score	0.050598 (rank : 376)	θ value	0.365318 (rank : 227)
Query Neighborhood Hits	357	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q86VN1, Q3ZCV7, Q5H9S1, Q5VXB6, Q9H8Z5, Q9Y3E3	Gene names	VPS36, C13orf9, EAP45
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 36 (ELL-associated protein of 45 kDa).

RNF17_MOUSE
NC score	0.050510 (rank : 377)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	35
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

PEX2_MOUSE
NC score	0.050042 (rank : 378)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	357	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

PCNT_MOUSE
NC score	0.048866 (rank : 379)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	357	Target Neighborhood Hits	1207	Shared Neighborhood Hits	105
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RBP24_HUMAN
NC score	0.048248 (rank : 380)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	357	Target Neighborhood Hits	1559	Shared Neighborhood Hits	130
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

NUMA1_HUMAN
NC score	0.048113 (rank : 381)	θ value	0.813845 (rank : 252)
Query Neighborhood Hits	357	Target Neighborhood Hits	1523	Shared Neighborhood Hits	111
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

GCC2_HUMAN
NC score	0.047971 (rank : 382)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	357	Target Neighborhood Hits	1558	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

VPS36_MOUSE
NC score	0.047143 (rank : 383)	θ value	0.62314 (rank : 245)
Query Neighborhood Hits	357	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XD6, Q9CVA3	Gene names	Vps36
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 36.

FA55D_MOUSE
NC score	0.046608 (rank : 384)	θ value	0.21417 (rank : 206)
Query Neighborhood Hits	357	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q52KP5, Q8BKY4	Gene names	Fam55d
Domain Architecture	No domain graphic available
Description	Protein FAM55D precursor.

GOGA4_HUMAN
NC score	0.046403 (rank : 385)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	357	Target Neighborhood Hits	2034	Shared Neighborhood Hits	143
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

T3JAM_MOUSE
NC score	0.045656 (rank : 386)	θ value	0.47712 (rank : 237)
Query Neighborhood Hits	357	Target Neighborhood Hits	535	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

RNF17_HUMAN
NC score	0.045502 (rank : 387)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	357	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

CNTRB_HUMAN
NC score	0.043271 (rank : 388)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	357	Target Neighborhood Hits	690	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

HOOK3_MOUSE
NC score	0.043262 (rank : 389)	θ value	0.0330416 (rank : 160)
Query Neighborhood Hits	357	Target Neighborhood Hits	1007	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.042618 (rank : 390)	θ value	0.0736092 (rank : 183)
Query Neighborhood Hits	357	Target Neighborhood Hits	1070	Shared Neighborhood Hits	83
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

SPTN2_HUMAN
NC score	0.042233 (rank : 391)	θ value	1.06291 (rank : 262)
Query Neighborhood Hits	357	Target Neighborhood Hits	535	Shared Neighborhood Hits	60
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

MIB2_HUMAN
NC score	0.041469 (rank : 392)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	357	Target Neighborhood Hits	438	Shared Neighborhood Hits	89
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MLL2_HUMAN
NC score	0.040478 (rank : 393)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	357	Target Neighborhood Hits	1788	Shared Neighborhood Hits	89
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CCHCR_HUMAN
NC score	0.039742 (rank : 394)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	357	Target Neighborhood Hits	717	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CP135_HUMAN
NC score	0.039660 (rank : 395)	θ value	0.0563607 (rank : 173)
Query Neighborhood Hits	357	Target Neighborhood Hits	1290	Shared Neighborhood Hits	94
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGA3_HUMAN
NC score	0.038614 (rank : 396)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	357	Target Neighborhood Hits	1317	Shared Neighborhood Hits	100
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

NEMO_HUMAN
NC score	0.038343 (rank : 397)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	357	Target Neighborhood Hits	820	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

MYH9_MOUSE
NC score	0.037886 (rank : 398)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	357	Target Neighborhood Hits	1829	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH10_MOUSE
NC score	0.037350 (rank : 399)	θ value	1.81305 (rank : 273)
Query Neighborhood Hits	357	Target Neighborhood Hits	1612	Shared Neighborhood Hits	119
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CENPU_MOUSE
NC score	0.037055 (rank : 400)	θ value	0.813845 (rank : 247)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

FLIP1_HUMAN
NC score	0.037036 (rank : 401)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MYH14_MOUSE
NC score	0.036877 (rank : 402)	θ value	0.365318 (rank : 219)
Query Neighborhood Hits	357	Target Neighborhood Hits	1225	Shared Neighborhood Hits	99
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

FYCO1_HUMAN
NC score	0.036713 (rank : 403)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	357	Target Neighborhood Hits	1149	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

K2C1B_MOUSE
NC score	0.036015 (rank : 404)	θ value	0.00298849 (rank : 131)
Query Neighborhood Hits	357	Target Neighborhood Hits	503	Shared Neighborhood Hits	61
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

MYH14_HUMAN
NC score	0.035898 (rank : 405)	θ value	0.0193708 (rank : 152)
Query Neighborhood Hits	357	Target Neighborhood Hits	995	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

K0552_HUMAN
NC score	0.035781 (rank : 406)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	357	Target Neighborhood Hits	442	Shared Neighborhood Hits	61
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

MYH10_HUMAN
NC score	0.035516 (rank : 407)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	357	Target Neighborhood Hits	1620	Shared Neighborhood Hits	121
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

GOGA1_MOUSE
NC score	0.035223 (rank : 408)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	357	Target Neighborhood Hits	994	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CP135_MOUSE
NC score	0.035071 (rank : 409)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	357	Target Neighborhood Hits	1278	Shared Neighborhood Hits	96
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RUFY1_HUMAN
NC score	0.033802 (rank : 410)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	357	Target Neighborhood Hits	848	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RABE2_MOUSE
NC score	0.033036 (rank : 411)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	357	Target Neighborhood Hits	598	Shared Neighborhood Hits	66
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RUFY1_MOUSE
NC score	0.032866 (rank : 412)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	357	Target Neighborhood Hits	765	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

LIPA1_HUMAN
NC score	0.032768 (rank : 413)	θ value	2.36792 (rank : 279)
Query Neighborhood Hits	357	Target Neighborhood Hits	1294	Shared Neighborhood Hits	95
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

PHLB1_HUMAN
NC score	0.032557 (rank : 414)	θ value	0.62314 (rank : 241)
Query Neighborhood Hits	357	Target Neighborhood Hits	1038	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

K2C1B_HUMAN
NC score	0.032554 (rank : 415)	θ value	0.0961366 (rank : 187)
Query Neighborhood Hits	357	Target Neighborhood Hits	542	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

MYH7_HUMAN
NC score	0.031306 (rank : 416)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	357	Target Neighborhood Hits	1559	Shared Neighborhood Hits	111
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

K2C8_HUMAN
NC score	0.031223 (rank : 417)	θ value	0.47712 (rank : 230)
Query Neighborhood Hits	357	Target Neighborhood Hits	593	Shared Neighborhood Hits	65
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

AMOL2_MOUSE
NC score	0.031054 (rank : 418)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	357	Target Neighborhood Hits	591	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

TPM4_MOUSE
NC score	0.030617 (rank : 419)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	357	Target Neighborhood Hits	703	Shared Neighborhood Hits	73
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

RBNS5_HUMAN
NC score	0.030503 (rank : 420)	θ value	0.365318 (rank : 220)
Query Neighborhood Hits	357	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

AMOL2_HUMAN
NC score	0.029990 (rank : 421)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	357	Target Neighborhood Hits	603	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

HIP1R_HUMAN
NC score	0.029711 (rank : 422)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	357	Target Neighborhood Hits	809	Shared Neighborhood Hits	78
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

K2C8_MOUSE
NC score	0.029594 (rank : 423)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	357	Target Neighborhood Hits	576	Shared Neighborhood Hits	68
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

K2C7_HUMAN
NC score	0.028579 (rank : 424)	θ value	0.0961366 (rank : 188)
Query Neighborhood Hits	357	Target Neighborhood Hits	369	Shared Neighborhood Hits	49
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

MY18B_HUMAN
NC score	0.027880 (rank : 425)	θ value	1.06291 (rank : 261)
Query Neighborhood Hits	357	Target Neighborhood Hits	1299	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

KRHB2_MOUSE
NC score	0.027602 (rank : 426)	θ value	0.0431538 (rank : 163)
Query Neighborhood Hits	357	Target Neighborhood Hits	233	Shared Neighborhood Hits	36
SwissProt Accessions	Q99M74	Gene names	Krthb2, Krt2-20
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

K2C1_HUMAN
NC score	0.026480 (rank : 427)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	357	Target Neighborhood Hits	624	Shared Neighborhood Hits	66
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

RIMB1_HUMAN
NC score	0.025657 (rank : 428)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	357	Target Neighborhood Hits	1479	Shared Neighborhood Hits	77
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PWP2_MOUSE
NC score	0.022823 (rank : 429)	θ value	0.279714 (rank : 215)
Query Neighborhood Hits	357	Target Neighborhood Hits	309	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

SKI_HUMAN
NC score	0.022738 (rank : 430)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	357	Target Neighborhood Hits	423	Shared Neighborhood Hits	45
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

NPTX2_HUMAN
NC score	0.022406 (rank : 431)	θ value	0.813845 (rank : 251)
Query Neighborhood Hits	357	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	P47972, Q86XV7, Q96G70	Gene names	NPTX2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NCOA4_HUMAN
NC score	0.021789 (rank : 432)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	357	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).

KRHB2_HUMAN
NC score	0.021321 (rank : 433)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	357	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

KIFC1_HUMAN
NC score	0.021099 (rank : 434)	θ value	0.813845 (rank : 249)
Query Neighborhood Hits	357	Target Neighborhood Hits	545	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

KRHB4_MOUSE
NC score	0.020770 (rank : 435)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	357	Target Neighborhood Hits	344	Shared Neighborhood Hits	44
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

CE025_HUMAN
NC score	0.019919 (rank : 436)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

FBX41_MOUSE
NC score	0.019178 (rank : 437)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	357	Target Neighborhood Hits	430	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_HUMAN
NC score	0.018059 (rank : 438)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	357	Target Neighborhood Hits	475	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

KIF5C_HUMAN
NC score	0.017808 (rank : 439)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	357	Target Neighborhood Hits	974	Shared Neighborhood Hits	79
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CCNL1_HUMAN
NC score	0.016249 (rank : 440)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	357	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CT004_MOUSE
NC score	0.015354 (rank : 441)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	357	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2V5, Q3TM16, Q8VBU9	Gene names
Domain Architecture
Description	Protein C20orf4 homolog.

KDEL1_MOUSE
NC score	0.014920 (rank : 442)	θ value	1.81305 (rank : 272)
Query Neighborhood Hits	357	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHP7, Q8BPU6, Q8C528, Q8R591, Q9D8P1	Gene names	Kdelc1, Ep58
Domain Architecture	No domain graphic available
Description	KDEL motif-containing protein 1 precursor (ER protein 58).

NF2L1_HUMAN
NC score	0.014630 (rank : 443)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	357	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
NC score	0.014596 (rank : 444)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	357	Target Neighborhood Hits	185	Shared Neighborhood Hits	15
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

RRMJ3_MOUSE
NC score	0.014437 (rank : 445)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	357	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

NPTX2_MOUSE
NC score	0.014280 (rank : 446)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	357	Target Neighborhood Hits	79	Shared Neighborhood Hits	11
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NFH_MOUSE
NC score	0.013652 (rank : 447)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	357	Target Neighborhood Hits	2247	Shared Neighborhood Hits	77
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NSF1C_MOUSE
NC score	0.010982 (rank : 448)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	357	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

ZDH19_MOUSE
NC score	0.006182 (rank : 449)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	357	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q810M5	Gene names	Zdhhc19
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC19 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 19) (DHHC-19).

AAKG2_HUMAN
NC score	0.006047 (rank : 450)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	357	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

LAMB3_HUMAN
NC score	0.004309 (rank : 451)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	357	Target Neighborhood Hits	461	Shared Neighborhood Hits	38
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

ICAM5_HUMAN
NC score	0.003413 (rank : 452)	θ value	1.06291 (rank : 260)
Query Neighborhood Hits	357	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

LAMC3_HUMAN
NC score	0.002634 (rank : 453)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	357	Target Neighborhood Hits	588	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

SNX12_HUMAN
NC score	0.002616 (rank : 454)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	357	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMY4, Q8WUG9	Gene names	SNX12
Domain Architecture
Description	Sorting nexin-12.

PTPRS_HUMAN
NC score	0.000571 (rank : 455)	θ value	0.813845 (rank : 253)
Query Neighborhood Hits	357	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

ATS4_MOUSE
NC score	0.000202 (rank : 456)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	357	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ANR47_HUMAN
NC score	-0.001232 (rank : 457)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	357	Target Neighborhood Hits	369	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

MRCKG_HUMAN
NC score	-0.001436 (rank : 458)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	357	Target Neighborhood Hits	1519	Shared Neighborhood Hits	69
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MK15_MOUSE
NC score	-0.004486 (rank : 459)	θ value	0.0736092 (rank : 184)
Query Neighborhood Hits	357	Target Neighborhood Hits	843	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

TAOK2_HUMAN
NC score	-0.005884 (rank : 460)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	357	Target Neighborhood Hits	1172	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).