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Network neighborhood for query Sequence : RC3H1_MOUSE

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RC3H1_MOUSE
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MNAB_HUMAN
θ value	0 (rank : 1)	NC score	0.954437 (rank : 2)
Query Neighborhood Hits	244	Target Neighborhood Hits	196	Shared Neighborhood Hits	124
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	0 (rank : 2)	NC score	0.948423 (rank : 4)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	126
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RC3H1_HUMAN
θ value	0 (rank : 3)	NC score	0.950657 (rank : 3)
Query Neighborhood Hits	244	Target Neighborhood Hits	433	Shared Neighborhood Hits	196
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	244	Target Neighborhood Hits	244	Shared Neighborhood Hits	244
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRI32_MOUSE
θ value	7.59969e-07 (rank : 5)	NC score	0.349113 (rank : 5)
Query Neighborhood Hits	244	Target Neighborhood Hits	271	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI32_HUMAN
θ value	2.88788e-06 (rank : 6)	NC score	0.344220 (rank : 6)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	121
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI50_MOUSE
θ value	3.19293e-05 (rank : 7)	NC score	0.265418 (rank : 13)
Query Neighborhood Hits	244	Target Neighborhood Hits	326	Shared Neighborhood Hits	133
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZC3H3_HUMAN
θ value	0.000270298 (rank : 8)	NC score	0.160297 (rank : 119)
Query Neighborhood Hits	244	Target Neighborhood Hits	159	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

TISB_HUMAN
θ value	0.000461057 (rank : 9)	NC score	0.261213 (rank : 15)
Query Neighborhood Hits	244	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISB_MOUSE
θ value	0.000602161 (rank : 10)	NC score	0.259798 (rank : 17)
Query Neighborhood Hits	244	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

Z3H7B_HUMAN
θ value	0.000602161 (rank : 11)	NC score	0.142853 (rank : 127)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

ZC3H5_HUMAN
θ value	0.00134147 (rank : 12)	NC score	0.208870 (rank : 65)
Query Neighborhood Hits	244	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

BRCA1_HUMAN
θ value	0.00298849 (rank : 13)	NC score	0.246839 (rank : 21)
Query Neighborhood Hits	244	Target Neighborhood Hits	381	Shared Neighborhood Hits	130
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI34_MOUSE
θ value	0.00298849 (rank : 14)	NC score	0.229506 (rank : 33)
Query Neighborhood Hits	244	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI47_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.251125 (rank : 20)
Query Neighborhood Hits	244	Target Neighborhood Hits	295	Shared Neighborhood Hits	128
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI50_HUMAN
θ value	0.00390308 (rank : 16)	NC score	0.252401 (rank : 19)
Query Neighborhood Hits	244	Target Neighborhood Hits	294	Shared Neighborhood Hits	130
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM5_HUMAN
θ value	0.00390308 (rank : 17)	NC score	0.242059 (rank : 26)
Query Neighborhood Hits	244	Target Neighborhood Hits	424	Shared Neighborhood Hits	134
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TISD_MOUSE
θ value	0.00509761 (rank : 18)	NC score	0.237867 (rank : 27)
Query Neighborhood Hits	244	Target Neighborhood Hits	62	Shared Neighborhood Hits	22
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

TRI59_MOUSE
θ value	0.00509761 (rank : 19)	NC score	0.298614 (rank : 7)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	126
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TTP_MOUSE
θ value	0.00509761 (rank : 20)	NC score	0.244585 (rank : 24)
Query Neighborhood Hits	244	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

TRAF6_HUMAN
θ value	0.00665767 (rank : 21)	NC score	0.206532 (rank : 72)
Query Neighborhood Hits	244	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TTP_HUMAN
θ value	0.00665767 (rank : 22)	NC score	0.237613 (rank : 28)
Query Neighborhood Hits	244	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

ZC3H5_MOUSE
θ value	0.00665767 (rank : 23)	NC score	0.195753 (rank : 88)
Query Neighborhood Hits	244	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ARD1_HUMAN
θ value	0.00869519 (rank : 24)	NC score	0.114729 (rank : 158)
Query Neighborhood Hits	244	Target Neighborhood Hits	621	Shared Neighborhood Hits	78
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	0.00869519 (rank : 25)	NC score	0.118763 (rank : 150)
Query Neighborhood Hits	244	Target Neighborhood Hits	573	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRAF6_MOUSE
θ value	0.00869519 (rank : 26)	NC score	0.206555 (rank : 71)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	117
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

RFPL3_HUMAN
θ value	0.0113563 (rank : 27)	NC score	0.205689 (rank : 75)
Query Neighborhood Hits	244	Target Neighborhood Hits	134	Shared Neighborhood Hits	85
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRI68_MOUSE
θ value	0.0113563 (rank : 28)	NC score	0.226143 (rank : 38)
Query Neighborhood Hits	244	Target Neighborhood Hits	356	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TISD_HUMAN
θ value	0.0148317 (rank : 29)	NC score	0.228667 (rank : 35)
Query Neighborhood Hits	244	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

TRI10_HUMAN
θ value	0.0148317 (rank : 30)	NC score	0.228967 (rank : 34)
Query Neighborhood Hits	244	Target Neighborhood Hits	315	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI47_HUMAN
θ value	0.0148317 (rank : 31)	NC score	0.243277 (rank : 25)
Query Neighborhood Hits	244	Target Neighborhood Hits	286	Shared Neighborhood Hits	127
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI59_HUMAN
θ value	0.0148317 (rank : 32)	NC score	0.291072 (rank : 8)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI74_HUMAN
θ value	0.0193708 (rank : 33)	NC score	0.267519 (rank : 12)
Query Neighborhood Hits	244	Target Neighborhood Hits	249	Shared Neighborhood Hits	124
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI10_MOUSE
θ value	0.0252991 (rank : 34)	NC score	0.224135 (rank : 45)
Query Neighborhood Hits	244	Target Neighborhood Hits	285	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI31_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.258419 (rank : 18)
Query Neighborhood Hits	244	Target Neighborhood Hits	299	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI34_HUMAN
θ value	0.0252991 (rank : 36)	NC score	0.232004 (rank : 32)
Query Neighborhood Hits	244	Target Neighborhood Hits	416	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRIM6_MOUSE
θ value	0.0252991 (rank : 37)	NC score	0.224413 (rank : 43)
Query Neighborhood Hits	244	Target Neighborhood Hits	451	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

HELZ_HUMAN
θ value	0.0431538 (rank : 38)	NC score	0.107033 (rank : 171)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RFPL2_HUMAN
θ value	0.0431538 (rank : 39)	NC score	0.194146 (rank : 93)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRIM4_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.237528 (rank : 29)
Query Neighborhood Hits	244	Target Neighborhood Hits	321	Shared Neighborhood Hits	128
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

ZC11A_MOUSE
θ value	0.0431538 (rank : 41)	NC score	0.048751 (rank : 241)
Query Neighborhood Hits	244	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

BRCA1_MOUSE
θ value	0.0563607 (rank : 42)	NC score	0.227364 (rank : 37)
Query Neighborhood Hits	244	Target Neighborhood Hits	436	Shared Neighborhood Hits	127
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

REPS2_MOUSE
θ value	0.0563607 (rank : 43)	NC score	0.038547 (rank : 255)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

RFPL1_HUMAN
θ value	0.0563607 (rank : 44)	NC score	0.190807 (rank : 95)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	78
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RNF4_MOUSE
θ value	0.0563607 (rank : 45)	NC score	0.228199 (rank : 36)
Query Neighborhood Hits	244	Target Neighborhood Hits	212	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI13_HUMAN
θ value	0.0563607 (rank : 46)	NC score	0.272998 (rank : 10)
Query Neighborhood Hits	244	Target Neighborhood Hits	274	Shared Neighborhood Hits	128
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI56_HUMAN
θ value	0.0563607 (rank : 47)	NC score	0.207011 (rank : 67)
Query Neighborhood Hits	244	Target Neighborhood Hits	339	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI73_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.260762 (rank : 16)
Query Neighborhood Hits	244	Target Neighborhood Hits	258	Shared Neighborhood Hits	126
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

RO52_HUMAN
θ value	0.0736092 (rank : 49)	NC score	0.220342 (rank : 49)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	133
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI68_HUMAN
θ value	0.0736092 (rank : 50)	NC score	0.219150 (rank : 52)
Query Neighborhood Hits	244	Target Neighborhood Hits	267	Shared Neighborhood Hits	123
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRIM6_HUMAN
θ value	0.0736092 (rank : 51)	NC score	0.224526 (rank : 42)
Query Neighborhood Hits	244	Target Neighborhood Hits	412	Shared Neighborhood Hits	129
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

ATX2L_MOUSE
θ value	0.0961366 (rank : 52)	NC score	0.060860 (rank : 231)
Query Neighborhood Hits	244	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

RN183_HUMAN
θ value	0.0961366 (rank : 53)	NC score	0.283055 (rank : 9)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF41_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.212773 (rank : 62)
Query Neighborhood Hits	244	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.212867 (rank : 61)
Query Neighborhood Hits	244	Target Neighborhood Hits	224	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	0.0961366 (rank : 56)	NC score	0.225977 (rank : 39)
Query Neighborhood Hits	244	Target Neighborhood Hits	212	Shared Neighborhood Hits	91
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI41_HUMAN
θ value	0.0961366 (rank : 57)	NC score	0.211334 (rank : 63)
Query Neighborhood Hits	244	Target Neighborhood Hits	349	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI60_HUMAN
θ value	0.0961366 (rank : 58)	NC score	0.216890 (rank : 55)
Query Neighborhood Hits	244	Target Neighborhood Hits	357	Shared Neighborhood Hits	130
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

FOXK1_MOUSE
θ value	0.125558 (rank : 59)	NC score	0.020876 (rank : 278)
Query Neighborhood Hits	244	Target Neighborhood Hits	215	Shared Neighborhood Hits	7
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

RN183_MOUSE
θ value	0.125558 (rank : 60)	NC score	0.269591 (rank : 11)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	78
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

Z3H7A_HUMAN
θ value	0.125558 (rank : 61)	NC score	0.123929 (rank : 142)
Query Neighborhood Hits	244	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

ZN313_MOUSE
θ value	0.125558 (rank : 62)	NC score	0.234935 (rank : 30)
Query Neighborhood Hits	244	Target Neighborhood Hits	273	Shared Neighborhood Hits	133
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RNF8_MOUSE
θ value	0.163984 (rank : 63)	NC score	0.181466 (rank : 103)
Query Neighborhood Hits	244	Target Neighborhood Hits	618	Shared Neighborhood Hits	131
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI13_MOUSE
θ value	0.163984 (rank : 64)	NC score	0.265254 (rank : 14)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI22_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.223878 (rank : 46)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI25_HUMAN
θ value	0.163984 (rank : 66)	NC score	0.221842 (rank : 48)
Query Neighborhood Hits	244	Target Neighborhood Hits	472	Shared Neighborhood Hits	133
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI40_HUMAN
θ value	0.163984 (rank : 67)	NC score	0.245066 (rank : 23)
Query Neighborhood Hits	244	Target Neighborhood Hits	279	Shared Neighborhood Hits	118
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

LNX1_HUMAN
θ value	0.21417 (rank : 68)	NC score	0.118209 (rank : 151)
Query Neighborhood Hits	244	Target Neighborhood Hits	379	Shared Neighborhood Hits	110
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	0.21417 (rank : 69)	NC score	0.119126 (rank : 149)
Query Neighborhood Hits	244	Target Neighborhood Hits	377	Shared Neighborhood Hits	108
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

NFX1_HUMAN
θ value	0.21417 (rank : 70)	NC score	0.033570 (rank : 262)
Query Neighborhood Hits	244	Target Neighborhood Hits	405	Shared Neighborhood Hits	11
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

RN168_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.225754 (rank : 40)
Query Neighborhood Hits	244	Target Neighborhood Hits	370	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI26_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.223076 (rank : 47)
Query Neighborhood Hits	244	Target Neighborhood Hits	339	Shared Neighborhood Hits	127
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.206756 (rank : 69)
Query Neighborhood Hits	244	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI63_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.214478 (rank : 59)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	110
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	0.21417 (rank : 75)	NC score	0.219822 (rank : 50)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	107
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM1_HUMAN
θ value	0.21417 (rank : 76)	NC score	0.206165 (rank : 73)
Query Neighborhood Hits	244	Target Neighborhood Hits	345	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.21417 (rank : 77)	NC score	0.204429 (rank : 76)
Query Neighborhood Hits	244	Target Neighborhood Hits	361	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRAF7_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.101406 (rank : 190)
Query Neighborhood Hits	244	Target Neighborhood Hits	482	Shared Neighborhood Hits	105
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.101974 (rank : 187)
Query Neighborhood Hits	244	Target Neighborhood Hits	470	Shared Neighborhood Hits	104
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI27_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.205702 (rank : 74)
Query Neighborhood Hits	244	Target Neighborhood Hits	261	Shared Neighborhood Hits	120
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI39_MOUSE
θ value	0.279714 (rank : 81)	NC score	0.199503 (rank : 83)
Query Neighborhood Hits	244	Target Neighborhood Hits	691	Shared Neighborhood Hits	131
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI54_HUMAN
θ value	0.279714 (rank : 82)	NC score	0.215542 (rank : 57)
Query Neighborhood Hits	244	Target Neighborhood Hits	209	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	0.279714 (rank : 83)	NC score	0.216562 (rank : 56)
Query Neighborhood Hits	244	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM7_HUMAN
θ value	0.279714 (rank : 84)	NC score	0.210785 (rank : 64)
Query Neighborhood Hits	244	Target Neighborhood Hits	336	Shared Neighborhood Hits	124
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

ZN313_HUMAN
θ value	0.279714 (rank : 85)	NC score	0.224911 (rank : 41)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

CN037_MOUSE
θ value	0.365318 (rank : 86)	NC score	0.042433 (rank : 248)
Query Neighborhood Hits	244	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

HM20A_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.046833 (rank : 242)
Query Neighborhood Hits	244	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	0.365318 (rank : 88)	NC score	0.046487 (rank : 243)
Query Neighborhood Hits	244	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

LNX2_MOUSE
θ value	0.365318 (rank : 89)	NC score	0.115717 (rank : 157)
Query Neighborhood Hits	244	Target Neighborhood Hits	407	Shared Neighborhood Hits	116
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MLL3_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.042505 (rank : 247)
Query Neighborhood Hits	244	Target Neighborhood Hits	1644	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RN123_HUMAN
θ value	0.365318 (rank : 91)	NC score	0.108257 (rank : 166)
Query Neighborhood Hits	244	Target Neighborhood Hits	175	Shared Neighborhood Hits	69
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

LNX2_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.116479 (rank : 154)
Query Neighborhood Hits	244	Target Neighborhood Hits	389	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MACF1_MOUSE
θ value	0.47712 (rank : 93)	NC score	0.013766 (rank : 300)
Query Neighborhood Hits	244	Target Neighborhood Hits	1313	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

NHLC1_MOUSE
θ value	0.47712 (rank : 94)	NC score	0.176726 (rank : 108)
Query Neighborhood Hits	244	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN166_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.195518 (rank : 89)
Query Neighborhood Hits	244	Target Neighborhood Hits	248	Shared Neighborhood Hits	119
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF8_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.157541 (rank : 121)
Query Neighborhood Hits	244	Target Neighborhood Hits	622	Shared Neighborhood Hits	128
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI18_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.201413 (rank : 80)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	121
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI26_HUMAN
θ value	0.47712 (rank : 98)	NC score	0.219296 (rank : 51)
Query Neighborhood Hits	244	Target Neighborhood Hits	335	Shared Neighborhood Hits	125
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI52_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.246051 (rank : 22)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	117
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI65_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.206986 (rank : 68)
Query Neighborhood Hits	244	Target Neighborhood Hits	340	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ZN281_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.003544 (rank : 324)
Query Neighborhood Hits	244	Target Neighborhood Hits	745	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2X9, Q9NY92	Gene names	ZNF281, GZP1, ZBP99
Domain Architecture	No domain graphic available
Description	Zinc finger protein 281 (Zinc finger DNA-binding protein 99) (Transcription factor ZBP-99) (GC-box-binding zinc finger protein 1).

NHLC1_HUMAN
θ value	0.62314 (rank : 102)	NC score	0.176203 (rank : 109)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

OPTN_MOUSE
θ value	0.62314 (rank : 103)	NC score	0.012125 (rank : 304)
Query Neighborhood Hits	244	Target Neighborhood Hits	1120	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RN168_MOUSE
θ value	0.62314 (rank : 104)	NC score	0.206747 (rank : 70)
Query Neighborhood Hits	244	Target Neighborhood Hits	440	Shared Neighborhood Hits	120
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI18_MOUSE
θ value	0.62314 (rank : 105)	NC score	0.201717 (rank : 79)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	124
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI25_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.217079 (rank : 54)
Query Neighborhood Hits	244	Target Neighborhood Hits	446	Shared Neighborhood Hits	132
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI56_MOUSE
θ value	0.62314 (rank : 107)	NC score	0.199861 (rank : 82)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	119
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRIM7_MOUSE
θ value	0.62314 (rank : 108)	NC score	0.207910 (rank : 66)
Query Neighborhood Hits	244	Target Neighborhood Hits	358	Shared Neighborhood Hits	125
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

ZC3H3_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.124501 (rank : 140)
Query Neighborhood Hits	244	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ANFY1_MOUSE
θ value	0.813845 (rank : 110)	NC score	0.019013 (rank : 285)
Query Neighborhood Hits	244	Target Neighborhood Hits	480	Shared Neighborhood Hits	13
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ATS14_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.008430 (rank : 309)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

MLL3_MOUSE
θ value	0.813845 (rank : 112)	NC score	0.041105 (rank : 251)
Query Neighborhood Hits	244	Target Neighborhood Hits	1399	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHC1_MOUSE
θ value	0.813845 (rank : 113)	NC score	0.035765 (rank : 259)
Query Neighborhood Hits	244	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

TRI30_MOUSE
θ value	0.813845 (rank : 114)	NC score	0.224203 (rank : 44)
Query Neighborhood Hits	244	Target Neighborhood Hits	434	Shared Neighborhood Hits	127
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI48_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.219034 (rank : 53)
Query Neighborhood Hits	244	Target Neighborhood Hits	192	Shared Neighborhood Hits	113
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

ZN516_MOUSE
θ value	0.813845 (rank : 116)	NC score	0.001461 (rank : 327)
Query Neighborhood Hits	244	Target Neighborhood Hits	1197	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CEL_HUMAN
θ value	1.06291 (rank : 117)	NC score	0.015592 (rank : 292)
Query Neighborhood Hits	244	Target Neighborhood Hits	896	Shared Neighborhood Hits	25
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ETV5_MOUSE
θ value	1.06291 (rank : 118)	NC score	0.013440 (rank : 302)
Query Neighborhood Hits	244	Target Neighborhood Hits	328	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

KTN1_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.022789 (rank : 277)
Query Neighborhood Hits	244	Target Neighborhood Hits	1197	Shared Neighborhood Hits	41
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

RN166_HUMAN
θ value	1.06291 (rank : 120)	NC score	0.189194 (rank : 96)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	115
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI12_MOUSE
θ value	1.06291 (rank : 121)	NC score	0.234809 (rank : 31)
Query Neighborhood Hits	244	Target Neighborhood Hits	387	Shared Neighborhood Hits	127
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

ZN750_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.029109 (rank : 267)
Query Neighborhood Hits	244	Target Neighborhood Hits	183	Shared Neighborhood Hits	8
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

HM20B_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.040513 (rank : 252)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

NOTC2_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.006715 (rank : 315)
Query Neighborhood Hits	244	Target Neighborhood Hits	1113	Shared Neighborhood Hits	17
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RAI2_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.044286 (rank : 245)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5P3, Q8N6X7	Gene names	RAI2
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 2.

RN123_MOUSE
θ value	1.38821 (rank : 126)	NC score	0.093154 (rank : 202)
Query Neighborhood Hits	244	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RNF32_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.106279 (rank : 178)
Query Neighborhood Hits	244	Target Neighborhood Hits	133	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

TRI39_HUMAN
θ value	1.38821 (rank : 128)	NC score	0.196986 (rank : 86)
Query Neighborhood Hits	244	Target Neighborhood Hits	693	Shared Neighborhood Hits	130
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI62_HUMAN
θ value	1.38821 (rank : 129)	NC score	0.198847 (rank : 85)
Query Neighborhood Hits	244	Target Neighborhood Hits	584	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	1.38821 (rank : 130)	NC score	0.202246 (rank : 78)
Query Neighborhood Hits	244	Target Neighborhood Hits	478	Shared Neighborhood Hits	117
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

VCIP1_HUMAN
θ value	1.38821 (rank : 131)	NC score	0.032915 (rank : 263)
Query Neighborhood Hits	244	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ZN179_HUMAN
θ value	1.38821 (rank : 132)	NC score	0.188584 (rank : 99)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ANFY1_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.016960 (rank : 288)
Query Neighborhood Hits	244	Target Neighborhood Hits	480	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ATX2L_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.039053 (rank : 254)
Query Neighborhood Hits	244	Target Neighborhood Hits	443	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BAZ2A_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.016441 (rank : 289)
Query Neighborhood Hits	244	Target Neighborhood Hits	780	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BRAP_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.067598 (rank : 228)
Query Neighborhood Hits	244	Target Neighborhood Hits	560	Shared Neighborhood Hits	44
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	1.81305 (rank : 137)	NC score	0.076410 (rank : 217)
Query Neighborhood Hits	244	Target Neighborhood Hits	409	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

MBD6_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.042946 (rank : 246)
Query Neighborhood Hits	244	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MNT_MOUSE
θ value	1.81305 (rank : 139)	NC score	0.034384 (rank : 261)
Query Neighborhood Hits	244	Target Neighborhood Hits	432	Shared Neighborhood Hits	24
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PZRN4_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.095871 (rank : 193)
Query Neighborhood Hits	244	Target Neighborhood Hits	438	Shared Neighborhood Hits	115
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRI55_HUMAN
θ value	1.81305 (rank : 141)	NC score	0.203752 (rank : 77)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TTK_MOUSE
θ value	1.81305 (rank : 142)	NC score	0.003775 (rank : 322)
Query Neighborhood Hits	244	Target Neighborhood Hits	803	Shared Neighborhood Hits	9
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

CBL_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.054947 (rank : 237)
Query Neighborhood Hits	244	Target Neighborhood Hits	426	Shared Neighborhood Hits	92
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MCA1_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.036323 (rank : 257)
Query Neighborhood Hits	244	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q12904, Q6FG28, Q96CQ9	Gene names	SCYE1, EMAP2
Domain Architecture
Description	Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)].

PABP3_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.020315 (rank : 279)
Query Neighborhood Hits	244	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H361, Q8NHV0, Q9H086	Gene names	PABPC3, PABP3, PABPL3
Domain Architecture
Description	Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP 3) (Testis-specific poly(A)-binding protein).

RNF39_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.195185 (rank : 90)
Query Neighborhood Hits	244	Target Neighborhood Hits	200	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

SIAH2_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.071628 (rank : 220)
Query Neighborhood Hits	244	Target Neighborhood Hits	94	Shared Neighborhood Hits	42
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	2.36792 (rank : 148)	NC score	0.070415 (rank : 223)
Query Neighborhood Hits	244	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SSXT_MOUSE
θ value	2.36792 (rank : 149)	NC score	0.038262 (rank : 256)
Query Neighborhood Hits	244	Target Neighborhood Hits	118	Shared Neighborhood Hits	13
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

TPR_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.011779 (rank : 305)
Query Neighborhood Hits	244	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAF4_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.106492 (rank : 176)
Query Neighborhood Hits	244	Target Neighborhood Hits	373	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRI15_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.192524 (rank : 94)
Query Neighborhood Hits	244	Target Neighborhood Hits	395	Shared Neighborhood Hits	120
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM8_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.215205 (rank : 58)
Query Neighborhood Hits	244	Target Neighborhood Hits	650	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	2.36792 (rank : 154)	NC score	0.214058 (rank : 60)
Query Neighborhood Hits	244	Target Neighborhood Hits	674	Shared Neighborhood Hits	132
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM9_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.180432 (rank : 106)
Query Neighborhood Hits	244	Target Neighborhood Hits	294	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.179967 (rank : 107)
Query Neighborhood Hits	244	Target Neighborhood Hits	274	Shared Neighborhood Hits	119
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

USH1C_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.027212 (rank : 270)
Query Neighborhood Hits	244	Target Neighborhood Hits	557	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

VCIP1_MOUSE
θ value	2.36792 (rank : 158)	NC score	0.031195 (rank : 264)
Query Neighborhood Hits	244	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

HGS_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.030241 (rank : 265)
Query Neighborhood Hits	244	Target Neighborhood Hits	589	Shared Neighborhood Hits	35
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LPP_HUMAN
θ value	3.0926 (rank : 160)	NC score	0.015363 (rank : 295)
Query Neighborhood Hits	244	Target Neighborhood Hits	775	Shared Neighborhood Hits	28
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAST4_HUMAN
θ value	3.0926 (rank : 161)	NC score	-0.000594 (rank : 331)
Query Neighborhood Hits	244	Target Neighborhood Hits	1804	Shared Neighborhood Hits	35
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MIRO2_MOUSE
θ value	3.0926 (rank : 162)	NC score	0.015453 (rank : 294)
Query Neighborhood Hits	244	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZN7	Gene names	Rhot2, Arht2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (Ras homolog gene family member T2).

RAG1_HUMAN
θ value	3.0926 (rank : 163)	NC score	0.134259 (rank : 130)
Query Neighborhood Hits	244	Target Neighborhood Hits	203	Shared Neighborhood Hits	95
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RGS3_HUMAN
θ value	3.0926 (rank : 164)	NC score	0.016221 (rank : 291)
Query Neighborhood Hits	244	Target Neighborhood Hits	1375	Shared Neighborhood Hits	44
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SUHW4_MOUSE
θ value	3.0926 (rank : 165)	NC score	0.001917 (rank : 326)
Query Neighborhood Hits	244	Target Neighborhood Hits	737	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TRI42_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.139589 (rank : 128)
Query Neighborhood Hits	244	Target Neighborhood Hits	283	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI45_MOUSE
θ value	3.0926 (rank : 167)	NC score	0.123640 (rank : 143)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI49_HUMAN
θ value	3.0926 (rank : 168)	NC score	0.199369 (rank : 84)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

ZIM10_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.019308 (rank : 281)
Query Neighborhood Hits	244	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ARHG1_MOUSE
θ value	4.03905 (rank : 170)	NC score	0.008698 (rank : 308)
Query Neighborhood Hits	244	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

BAI2_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.004270 (rank : 319)
Query Neighborhood Hits	244	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CD2L1_MOUSE
θ value	4.03905 (rank : 172)	NC score	0.000297 (rank : 330)
Query Neighborhood Hits	244	Target Neighborhood Hits	1463	Shared Neighborhood Hits	26
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DACT1_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.018314 (rank : 286)
Query Neighborhood Hits	244	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

HGS_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.028119 (rank : 268)
Query Neighborhood Hits	244	Target Neighborhood Hits	517	Shared Neighborhood Hits	32
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

PABP1_HUMAN
θ value	4.03905 (rank : 175)	NC score	0.023055 (rank : 274)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
θ value	4.03905 (rank : 176)	NC score	0.022973 (rank : 275)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	7
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

RERE_MOUSE
θ value	4.03905 (rank : 177)	NC score	0.034855 (rank : 260)
Query Neighborhood Hits	244	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SSXT_HUMAN
θ value	4.03905 (rank : 178)	NC score	0.035935 (rank : 258)
Query Neighborhood Hits	244	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

STK3_MOUSE
θ value	4.03905 (rank : 179)	NC score	-0.001828 (rank : 337)
Query Neighborhood Hits	244	Target Neighborhood Hits	869	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

TRI45_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.127813 (rank : 137)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI46_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.166615 (rank : 111)
Query Neighborhood Hits	244	Target Neighborhood Hits	291	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	4.03905 (rank : 182)	NC score	0.165956 (rank : 112)
Query Neighborhood Hits	244	Target Neighborhood Hits	287	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI65_HUMAN
θ value	4.03905 (rank : 183)	NC score	0.200695 (rank : 81)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	123
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

6PGL_MOUSE
θ value	5.27518 (rank : 184)	NC score	0.015575 (rank : 293)
Query Neighborhood Hits	244	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQ60, Q3TA62	Gene names	Pgls
Domain Architecture	No domain graphic available
Description	6-phosphogluconolactonase (EC 3.1.1.31) (6PGL).

FGD6_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.015015 (rank : 296)
Query Neighborhood Hits	244	Target Neighborhood Hits	237	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	5.27518 (rank : 186)	NC score	0.014804 (rank : 298)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

GGEE2_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.016416 (rank : 290)
Query Neighborhood Hits	244	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2X7, Q5JRK7, Q5JRK8	Gene names	PAGE2, GAGEE2
Domain Architecture	No domain graphic available
Description	G antigen family E member 2 (Prostate-associated gene 2 protein) (PAGE-2).

IF4G2_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.014876 (rank : 297)
Query Neighborhood Hits	244	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

IL3RB_MOUSE
θ value	5.27518 (rank : 189)	NC score	0.011504 (rank : 306)
Query Neighborhood Hits	244	Target Neighborhood Hits	355	Shared Neighborhood Hits	14
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

LRFN2_MOUSE
θ value	5.27518 (rank : 190)	NC score	0.002833 (rank : 325)
Query Neighborhood Hits	244	Target Neighborhood Hits	450	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

MDC1_HUMAN
θ value	5.27518 (rank : 191)	NC score	0.008093 (rank : 312)
Query Neighborhood Hits	244	Target Neighborhood Hits	1446	Shared Neighborhood Hits	34
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PML_MOUSE
θ value	5.27518 (rank : 192)	NC score	0.106925 (rank : 173)
Query Neighborhood Hits	244	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

R113A_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.106386 (rank : 177)
Query Neighborhood Hits	244	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RAD18_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.123493 (rank : 144)
Query Neighborhood Hits	244	Target Neighborhood Hits	230	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RMD5B_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.041213 (rank : 250)
Query Neighborhood Hits	244	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96G75, Q6UVY7, Q9H6F6	Gene names	RMND5B
Domain Architecture
Description	RMD5 homolog B.

RMD5B_MOUSE
θ value	5.27518 (rank : 196)	NC score	0.040437 (rank : 253)
Query Neighborhood Hits	244	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YQ7	Gene names	Rmnd5b
Domain Architecture
Description	RMD5 homolog B.

RN152_HUMAN
θ value	5.27518 (rank : 197)	NC score	0.161522 (rank : 117)
Query Neighborhood Hits	244	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	5.27518 (rank : 198)	NC score	0.164835 (rank : 114)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

STMN4_HUMAN
θ value	5.27518 (rank : 199)	NC score	0.019245 (rank : 282)
Query Neighborhood Hits	244	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	5.27518 (rank : 200)	NC score	0.019241 (rank : 283)
Query Neighborhood Hits	244	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

TRI36_MOUSE
θ value	5.27518 (rank : 201)	NC score	0.150670 (rank : 122)
Query Neighborhood Hits	244	Target Neighborhood Hits	266	Shared Neighborhood Hits	110
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI66_HUMAN
θ value	5.27518 (rank : 202)	NC score	0.042061 (rank : 249)
Query Neighborhood Hits	244	Target Neighborhood Hits	479	Shared Neighborhood Hits	58
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UHRF1_HUMAN
θ value	5.27518 (rank : 203)	NC score	0.097474 (rank : 192)
Query Neighborhood Hits	244	Target Neighborhood Hits	272	Shared Neighborhood Hits	102
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CRUM1_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.001408 (rank : 328)
Query Neighborhood Hits	244	Target Neighborhood Hits	457	Shared Neighborhood Hits	3
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

ETV6_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.008224 (rank : 311)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

FUBP2_HUMAN
θ value	6.88961 (rank : 206)	NC score	0.025962 (rank : 272)
Query Neighborhood Hits	244	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

HM20B_MOUSE
θ value	6.88961 (rank : 207)	NC score	0.030057 (rank : 266)
Query Neighborhood Hits	244	Target Neighborhood Hits	122	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

MCA1_MOUSE
θ value	6.88961 (rank : 208)	NC score	0.026414 (rank : 271)
Query Neighborhood Hits	244	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	P31230, Q60659	Gene names	Scye1, Emap2
Domain Architecture
Description	Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)].

PCNT_HUMAN
θ value	6.88961 (rank : 209)	NC score	0.014268 (rank : 299)
Query Neighborhood Hits	244	Target Neighborhood Hits	1551	Shared Neighborhood Hits	56
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

R113B_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.115826 (rank : 155)
Query Neighborhood Hits	244	Target Neighborhood Hits	165	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAG1_MOUSE
θ value	6.88961 (rank : 211)	NC score	0.128538 (rank : 134)
Query Neighborhood Hits	244	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RGS3_MOUSE
θ value	6.88961 (rank : 212)	NC score	0.019926 (rank : 280)
Query Neighborhood Hits	244	Target Neighborhood Hits	1621	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RIN3_MOUSE
θ value	6.88961 (rank : 213)	NC score	0.024137 (rank : 273)
Query Neighborhood Hits	244	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RN125_HUMAN
θ value	6.88961 (rank : 214)	NC score	0.176151 (rank : 110)
Query Neighborhood Hits	244	Target Neighborhood Hits	230	Shared Neighborhood Hits	111
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RO52_MOUSE
θ value	6.88961 (rank : 215)	NC score	0.196125 (rank : 87)
Query Neighborhood Hits	244	Target Neighborhood Hits	360	Shared Neighborhood Hits	126
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RP3A_MOUSE
θ value	6.88961 (rank : 216)	NC score	0.003943 (rank : 321)
Query Neighborhood Hits	244	Target Neighborhood Hits	510	Shared Neighborhood Hits	15
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TRAF5_MOUSE
θ value	6.88961 (rank : 217)	NC score	0.105983 (rank : 179)
Query Neighborhood Hits	244	Target Neighborhood Hits	355	Shared Neighborhood Hits	101
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI36_HUMAN
θ value	6.88961 (rank : 218)	NC score	0.150451 (rank : 123)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI42_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.130284 (rank : 132)
Query Neighborhood Hits	244	Target Neighborhood Hits	316	Shared Neighborhood Hits	91
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UHRF1_MOUSE
θ value	6.88961 (rank : 220)	NC score	0.094806 (rank : 196)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ZC313_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.019157 (rank : 284)
Query Neighborhood Hits	244	Target Neighborhood Hits	772	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZFY21_MOUSE
θ value	6.88961 (rank : 222)	NC score	0.022848 (rank : 276)
Query Neighborhood Hits	244	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

BCLF1_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.027258 (rank : 269)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CD2L1_HUMAN
θ value	8.99809 (rank : 224)	NC score	-0.000920 (rank : 333)
Query Neighborhood Hits	244	Target Neighborhood Hits	1467	Shared Neighborhood Hits	29
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L2_HUMAN
θ value	8.99809 (rank : 225)	NC score	-0.001118 (rank : 335)
Query Neighborhood Hits	244	Target Neighborhood Hits	1439	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

COHA1_HUMAN
θ value	8.99809 (rank : 226)	NC score	0.005840 (rank : 316)
Query Neighborhood Hits	244	Target Neighborhood Hits	400	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DOK1_MOUSE
θ value	8.99809 (rank : 227)	NC score	0.007048 (rank : 314)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

EGR4_HUMAN
θ value	8.99809 (rank : 228)	NC score	-0.000670 (rank : 332)
Query Neighborhood Hits	244	Target Neighborhood Hits	939	Shared Neighborhood Hits	15
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

GP176_MOUSE
θ value	8.99809 (rank : 229)	NC score	-0.000977 (rank : 334)
Query Neighborhood Hits	244	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

HAP1_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.008267 (rank : 310)
Query Neighborhood Hits	244	Target Neighborhood Hits	606	Shared Neighborhood Hits	26
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HG2A_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.013720 (rank : 301)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

IF4G2_MOUSE
θ value	8.99809 (rank : 232)	NC score	0.012979 (rank : 303)
Query Neighborhood Hits	244	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

LYAG_MOUSE
θ value	8.99809 (rank : 233)	NC score	0.005536 (rank : 317)
Query Neighborhood Hits	244	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).

MYO5B_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.001355 (rank : 329)
Query Neighborhood Hits	244	Target Neighborhood Hits	911	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

PDLI7_HUMAN
θ value	8.99809 (rank : 235)	NC score	0.003729 (rank : 323)
Query Neighborhood Hits	244	Target Neighborhood Hits	547	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

RAD18_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.101564 (rank : 189)
Query Neighborhood Hits	244	Target Neighborhood Hits	284	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

SI1L3_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.005049 (rank : 318)
Query Neighborhood Hits	244	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIP1_HUMAN
θ value	8.99809 (rank : 238)	NC score	-0.001538 (rank : 336)
Query Neighborhood Hits	244	Target Neighborhood Hits	832	Shared Neighborhood Hits	12
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SNX19_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.011431 (rank : 307)
Query Neighborhood Hits	244	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

TACC2_MOUSE
θ value	8.99809 (rank : 240)	NC score	0.007889 (rank : 313)
Query Neighborhood Hits	244	Target Neighborhood Hits	774	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TBX21_MOUSE
θ value	8.99809 (rank : 241)	NC score	0.004242 (rank : 320)
Query Neighborhood Hits	244	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TRI38_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.188623 (rank : 98)
Query Neighborhood Hits	244	Target Neighborhood Hits	373	Shared Neighborhood Hits	124
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRM1_HUMAN
θ value	8.99809 (rank : 243)	NC score	0.018059 (rank : 287)
Query Neighborhood Hits	244	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

ZN645_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.044485 (rank : 244)
Query Neighborhood Hits	244	Target Neighborhood Hits	265	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

AMFR2_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.051301 (rank : 239)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.051038 (rank : 240)
Query Neighborhood Hits	244	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

BFAR_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.129174 (rank : 133)
Query Neighborhood Hits	244	Target Neighborhood Hits	222	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.124553 (rank : 139)
Query Neighborhood Hits	244	Target Neighborhood Hits	232	Shared Neighborhood Hits	97
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC7_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.071083 (rank : 221)
Query Neighborhood Hits	244	Target Neighborhood Hits	185	Shared Neighborhood Hits	96
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BSPRY_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.110393 (rank : 161)
Query Neighborhood Hits	244	Target Neighborhood Hits	115	Shared Neighborhood Hits	55
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.112541 (rank : 160)
Query Neighborhood Hits	244	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.108300 (rank : 165)
Query Neighborhood Hits	244	Target Neighborhood Hits	322	Shared Neighborhood Hits	52
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.108796 (rank : 164)
Query Neighborhood Hits	244	Target Neighborhood Hits	252	Shared Neighborhood Hits	52
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.103722 (rank : 182)
Query Neighborhood Hits	244	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.107000 (rank : 172)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.101795 (rank : 188)
Query Neighborhood Hits	244	Target Neighborhood Hits	195	Shared Neighborhood Hits	48
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.110000 (rank : 162)
Query Neighborhood Hits	244	Target Neighborhood Hits	229	Shared Neighborhood Hits	53
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.109892 (rank : 163)
Query Neighborhood Hits	244	Target Neighborhood Hits	233	Shared Neighborhood Hits	52
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.108218 (rank : 167)
Query Neighborhood Hits	244	Target Neighborhood Hits	143	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.104010 (rank : 181)
Query Neighborhood Hits	244	Target Neighborhood Hits	177	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.107272 (rank : 169)
Query Neighborhood Hits	244	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CHFR_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.094778 (rank : 197)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.094199 (rank : 199)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	93
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.061483 (rank : 230)
Query Neighborhood Hits	244	Target Neighborhood Hits	422	Shared Neighborhood Hits	74
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.070800 (rank : 222)
Query Neighborhood Hits	244	Target Neighborhood Hits	416	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.095533 (rank : 194)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.100341 (rank : 191)
Query Neighborhood Hits	244	Target Neighborhood Hits	202	Shared Neighborhood Hits	90
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ERMAP_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.124065 (rank : 141)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.115756 (rank : 156)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

MEFV_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.149645 (rank : 124)
Query Neighborhood Hits	244	Target Neighborhood Hits	431	Shared Neighborhood Hits	81
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.133824 (rank : 131)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

PCGF6_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.058927 (rank : 233)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.059671 (rank : 232)
Query Neighborhood Hits	244	Target Neighborhood Hits	163	Shared Neighborhood Hits	72
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PEX10_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.134947 (rank : 129)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	102
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PML_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.093876 (rank : 201)
Query Neighborhood Hits	244	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PZRN3_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.078858 (rank : 215)
Query Neighborhood Hits	244	Target Neighborhood Hits	461	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.079401 (rank : 214)
Query Neighborhood Hits	244	Target Neighborhood Hits	447	Shared Neighborhood Hits	108
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RFWD2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.091354 (rank : 205)
Query Neighborhood Hits	244	Target Neighborhood Hits	518	Shared Neighborhood Hits	116
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.090537 (rank : 206)
Query Neighborhood Hits	244	Target Neighborhood Hits	535	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.116784 (rank : 152)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	98
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.114414 (rank : 159)
Query Neighborhood Hits	244	Target Neighborhood Hits	220	Shared Neighborhood Hits	97
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.106846 (rank : 174)
Query Neighborhood Hits	244	Target Neighborhood Hits	201	Shared Neighborhood Hits	92
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.106827 (rank : 175)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.158550 (rank : 120)
Query Neighborhood Hits	244	Target Neighborhood Hits	220	Shared Neighborhood Hits	105
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN141_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.081847 (rank : 211)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.081582 (rank : 212)
Query Neighborhood Hits	244	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.094810 (rank : 195)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.094101 (rank : 200)
Query Neighborhood Hits	244	Target Neighborhood Hits	161	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN169_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.102254 (rank : 186)
Query Neighborhood Hits	244	Target Neighborhood Hits	203	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN185_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.103193 (rank : 184)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	95
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.103043 (rank : 185)
Query Neighborhood Hits	244	Target Neighborhood Hits	211	Shared Neighborhood Hits	95
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.084222 (rank : 210)
Query Neighborhood Hits	244	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF5_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.107462 (rank : 168)
Query Neighborhood Hits	244	Target Neighborhood Hits	206	Shared Neighborhood Hits	91
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.107039 (rank : 170)
Query Neighborhood Hits	244	Target Neighborhood Hits	206	Shared Neighborhood Hits	89
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SMR3B_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.094434 (rank : 198)
Query Neighborhood Hits	244	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SMRA3_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.081063 (rank : 213)
Query Neighborhood Hits	244	Target Neighborhood Hits	265	Shared Neighborhood Hits	108
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.078302 (rank : 216)
Query Neighborhood Hits	244	Target Neighborhood Hits	267	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SPRY4_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.103690 (rank : 183)
Query Neighborhood Hits	244	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.104463 (rank : 180)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TIF1A_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.053509 (rank : 238)
Query Neighborhood Hits	244	Target Neighborhood Hits	327	Shared Neighborhood Hits	77
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1B_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.075981 (rank : 218)
Query Neighborhood Hits	244	Target Neighborhood Hits	312	Shared Neighborhood Hits	77
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.074936 (rank : 219)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	74
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.085920 (rank : 209)
Query Neighborhood Hits	244	Target Neighborhood Hits	410	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.086081 (rank : 208)
Query Neighborhood Hits	244	Target Neighborhood Hits	498	Shared Neighborhood Hits	102
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TOPRS_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.055414 (rank : 236)
Query Neighborhood Hits	244	Target Neighborhood Hits	286	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.055579 (rank : 235)
Query Neighborhood Hits	244	Target Neighborhood Hits	263	Shared Neighborhood Hits	65
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.066978 (rank : 229)
Query Neighborhood Hits	244	Target Neighborhood Hits	402	Shared Neighborhood Hits	85
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.068388 (rank : 226)
Query Neighborhood Hits	244	Target Neighborhood Hits	394	Shared Neighborhood Hits	88
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.069333 (rank : 225)
Query Neighborhood Hits	244	Target Neighborhood Hits	463	Shared Neighborhood Hits	91
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.069513 (rank : 224)
Query Neighborhood Hits	244	Target Neighborhood Hits	476	Shared Neighborhood Hits	92
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.068152 (rank : 227)
Query Neighborhood Hits	244	Target Neighborhood Hits	338	Shared Neighborhood Hits	65
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.086479 (rank : 207)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	93
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRI11_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.187406 (rank : 101)
Query Neighborhood Hits	244	Target Neighborhood Hits	316	Shared Neighborhood Hits	122
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.187811 (rank : 100)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	122
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI14_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.148621 (rank : 126)
Query Neighborhood Hits	244	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.148981 (rank : 125)
Query Neighborhood Hits	244	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI16_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.121746 (rank : 145)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.125080 (rank : 138)
Query Neighborhood Hits	244	Target Neighborhood Hits	196	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI17_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.186003 (rank : 102)
Query Neighborhood Hits	244	Target Neighborhood Hits	318	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI17_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.181070 (rank : 105)
Query Neighborhood Hits	244	Target Neighborhood Hits	620	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI29_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.116626 (rank : 153)
Query Neighborhood Hits	244	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.120153 (rank : 148)
Query Neighborhood Hits	244	Target Neighborhood Hits	306	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI35_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.195160 (rank : 91)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.195116 (rank : 92)
Query Neighborhood Hits	244	Target Neighborhood Hits	465	Shared Neighborhood Hits	127
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.128284 (rank : 136)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.128413 (rank : 135)
Query Neighborhood Hits	244	Target Neighborhood Hits	316	Shared Neighborhood Hits	95
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI43_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.188677 (rank : 97)
Query Neighborhood Hits	244	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI44_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.120207 (rank : 147)
Query Neighborhood Hits	244	Target Neighborhood Hits	393	Shared Neighborhood Hits	78
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.120404 (rank : 146)
Query Neighborhood Hits	244	Target Neighborhood Hits	327	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI60_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.181309 (rank : 104)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.165134 (rank : 113)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.164479 (rank : 116)
Query Neighborhood Hits	244	Target Neighborhood Hits	331	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.164680 (rank : 115)
Query Neighborhood Hits	244	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.161484 (rank : 118)
Query Neighborhood Hits	244	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

UB7I3_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.057541 (rank : 234)
Query Neighborhood Hits	244	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UHRF2_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.091604 (rank : 204)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	105
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.092117 (rank : 203)
Query Neighborhood Hits	244	Target Neighborhood Hits	275	Shared Neighborhood Hits	107
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

Hits sorted by NC score

RC3H1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	244	Target Neighborhood Hits	244	Shared Neighborhood Hits	244
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

MNAB_HUMAN
NC score	0.954437 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	244	Target Neighborhood Hits	196	Shared Neighborhood Hits	124
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

RC3H1_HUMAN
NC score	0.950657 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	244	Target Neighborhood Hits	433	Shared Neighborhood Hits	196
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

MNAB_MOUSE
NC score	0.948423 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	126
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

TRI32_MOUSE
NC score	0.349113 (rank : 5)	θ value	7.59969e-07 (rank : 5)
Query Neighborhood Hits	244	Target Neighborhood Hits	271	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI32_HUMAN
NC score	0.344220 (rank : 6)	θ value	2.88788e-06 (rank : 6)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	121
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI59_MOUSE
NC score	0.298614 (rank : 7)	θ value	0.00509761 (rank : 19)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	126
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.291072 (rank : 8)	θ value	0.0148317 (rank : 32)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

RN183_HUMAN
NC score	0.283055 (rank : 9)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI13_HUMAN
NC score	0.272998 (rank : 10)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	244	Target Neighborhood Hits	274	Shared Neighborhood Hits	128
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

RN183_MOUSE
NC score	0.269591 (rank : 11)	θ value	0.125558 (rank : 60)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	78
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI74_HUMAN
NC score	0.267519 (rank : 12)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	244	Target Neighborhood Hits	249	Shared Neighborhood Hits	124
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI50_MOUSE
NC score	0.265418 (rank : 13)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	244	Target Neighborhood Hits	326	Shared Neighborhood Hits	133
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI13_MOUSE
NC score	0.265254 (rank : 14)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TISB_HUMAN
NC score	0.261213 (rank : 15)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	244	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TRI73_HUMAN
NC score	0.260762 (rank : 16)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	244	Target Neighborhood Hits	258	Shared Neighborhood Hits	126
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TISB_MOUSE
NC score	0.259798 (rank : 17)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	244	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

TRI31_HUMAN
NC score	0.258419 (rank : 18)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	244	Target Neighborhood Hits	299	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI50_HUMAN
NC score	0.252401 (rank : 19)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	244	Target Neighborhood Hits	294	Shared Neighborhood Hits	130
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI47_MOUSE
NC score	0.251125 (rank : 20)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	244	Target Neighborhood Hits	295	Shared Neighborhood Hits	128
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

BRCA1_HUMAN
NC score	0.246839 (rank : 21)	θ value	0.00298849 (rank : 13)
Query Neighborhood Hits	244	Target Neighborhood Hits	381	Shared Neighborhood Hits	130
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI52_HUMAN
NC score	0.246051 (rank : 22)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	117
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI40_HUMAN
NC score	0.245066 (rank : 23)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	244	Target Neighborhood Hits	279	Shared Neighborhood Hits	118
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TTP_MOUSE
NC score	0.244585 (rank : 24)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	244	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

TRI47_HUMAN
NC score	0.243277 (rank : 25)	θ value	0.0148317 (rank : 31)
Query Neighborhood Hits	244	Target Neighborhood Hits	286	Shared Neighborhood Hits	127
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRIM5_HUMAN
NC score	0.242059 (rank : 26)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	244	Target Neighborhood Hits	424	Shared Neighborhood Hits	134
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TISD_MOUSE
NC score	0.237867 (rank : 27)	θ value	0.00509761 (rank : 18)
Query Neighborhood Hits	244	Target Neighborhood Hits	62	Shared Neighborhood Hits	22
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

TTP_HUMAN
NC score	0.237613 (rank : 28)	θ value	0.00665767 (rank : 22)
Query Neighborhood Hits	244	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

TRIM4_HUMAN
NC score	0.237528 (rank : 29)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	244	Target Neighborhood Hits	321	Shared Neighborhood Hits	128
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

ZN313_MOUSE
NC score	0.234935 (rank : 30)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	244	Target Neighborhood Hits	273	Shared Neighborhood Hits	133
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI12_MOUSE
NC score	0.234809 (rank : 31)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	244	Target Neighborhood Hits	387	Shared Neighborhood Hits	127
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI34_HUMAN
NC score	0.232004 (rank : 32)	θ value	0.0252991 (rank : 36)
Query Neighborhood Hits	244	Target Neighborhood Hits	416	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
NC score	0.229506 (rank : 33)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	244	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI10_HUMAN
NC score	0.228967 (rank : 34)	θ value	0.0148317 (rank : 30)
Query Neighborhood Hits	244	Target Neighborhood Hits	315	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TISD_HUMAN
NC score	0.228667 (rank : 35)	θ value	0.0148317 (rank : 29)
Query Neighborhood Hits	244	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

RNF4_MOUSE
NC score	0.228199 (rank : 36)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	244	Target Neighborhood Hits	212	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

BRCA1_MOUSE
NC score	0.227364 (rank : 37)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	244	Target Neighborhood Hits	436	Shared Neighborhood Hits	127
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRI68_MOUSE
NC score	0.226143 (rank : 38)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	244	Target Neighborhood Hits	356	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RNF4_HUMAN
NC score	0.225977 (rank : 39)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	244	Target Neighborhood Hits	212	Shared Neighborhood Hits	91
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RN168_HUMAN
NC score	0.225754 (rank : 40)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	244	Target Neighborhood Hits	370	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN313_HUMAN
NC score	0.224911 (rank : 41)	θ value	0.279714 (rank : 85)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRIM6_HUMAN
NC score	0.224526 (rank : 42)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	244	Target Neighborhood Hits	412	Shared Neighborhood Hits	129
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
NC score	0.224413 (rank : 43)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	244	Target Neighborhood Hits	451	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI30_MOUSE
NC score	0.224203 (rank : 44)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	244	Target Neighborhood Hits	434	Shared Neighborhood Hits	127
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI10_MOUSE
NC score	0.224135 (rank : 45)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	244	Target Neighborhood Hits	285	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI22_HUMAN
NC score	0.223878 (rank : 46)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI26_MOUSE
NC score	0.223076 (rank : 47)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	244	Target Neighborhood Hits	339	Shared Neighborhood Hits	127
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI25_HUMAN
NC score	0.221842 (rank : 48)	θ value	0.163984 (rank : 66)
Query Neighborhood Hits	244	Target Neighborhood Hits	472	Shared Neighborhood Hits	133
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

RO52_HUMAN
NC score	0.220342 (rank : 49)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	133
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI63_MOUSE
NC score	0.219822 (rank : 50)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	107
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI26_HUMAN
NC score	0.219296 (rank : 51)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	244	Target Neighborhood Hits	335	Shared Neighborhood Hits	125
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI68_HUMAN
NC score	0.219150 (rank : 52)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	244	Target Neighborhood Hits	267	Shared Neighborhood Hits	123
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI48_HUMAN
NC score	0.219034 (rank : 53)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	244	Target Neighborhood Hits	192	Shared Neighborhood Hits	113
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI25_MOUSE
NC score	0.217079 (rank : 54)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	244	Target Neighborhood Hits	446	Shared Neighborhood Hits	132
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI60_HUMAN
NC score	0.216890 (rank : 55)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	244	Target Neighborhood Hits	357	Shared Neighborhood Hits	130
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI54_MOUSE
NC score	0.216562 (rank : 56)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	244	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_HUMAN
NC score	0.215542 (rank : 57)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	244	Target Neighborhood Hits	209	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM8_HUMAN
NC score	0.215205 (rank : 58)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	244	Target Neighborhood Hits	650	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI63_HUMAN
NC score	0.214478 (rank : 59)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	110
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM8_MOUSE
NC score	0.214058 (rank : 60)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	244	Target Neighborhood Hits	674	Shared Neighborhood Hits	132
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RNF41_MOUSE
NC score	0.212867 (rank : 61)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	244	Target Neighborhood Hits	224	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.212773 (rank : 62)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	244	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRI41_HUMAN
NC score	0.211334 (rank : 63)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	244	Target Neighborhood Hits	349	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM7_HUMAN
NC score	0.210785 (rank : 64)	θ value	0.279714 (rank : 84)
Query Neighborhood Hits	244	Target Neighborhood Hits	336	Shared Neighborhood Hits	124
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

ZC3H5_HUMAN
NC score	0.208870 (rank : 65)	θ value	0.00134147 (rank : 12)
Query Neighborhood Hits	244	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

TRIM7_MOUSE
NC score	0.207910 (rank : 66)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	244	Target Neighborhood Hits	358	Shared Neighborhood Hits	125
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI56_HUMAN
NC score	0.207011 (rank : 67)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	244	Target Neighborhood Hits	339	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI65_MOUSE
NC score	0.206986 (rank : 68)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	244	Target Neighborhood Hits	340	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI27_HUMAN
NC score	0.206756 (rank : 69)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	244	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

RN168_MOUSE
NC score	0.206747 (rank : 70)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	244	Target Neighborhood Hits	440	Shared Neighborhood Hits	120
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRAF6_MOUSE
NC score	0.206555 (rank : 71)	θ value	0.00869519 (rank : 26)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	117
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF6_HUMAN
NC score	0.206532 (rank : 72)	θ value	0.00665767 (rank : 21)
Query Neighborhood Hits	244	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRIM1_HUMAN
NC score	0.206165 (rank : 73)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	244	Target Neighborhood Hits	345	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI27_MOUSE
NC score	0.205702 (rank : 74)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	244	Target Neighborhood Hits	261	Shared Neighborhood Hits	120
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

RFPL3_HUMAN
NC score	0.205689 (rank : 75)	θ value	0.0113563 (rank : 27)
Query Neighborhood Hits	244	Target Neighborhood Hits	134	Shared Neighborhood Hits	85
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRIM1_MOUSE
NC score	0.204429 (rank : 76)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	244	Target Neighborhood Hits	361	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI55_HUMAN
NC score	0.203752 (rank : 77)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI62_MOUSE
NC score	0.202246 (rank : 78)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	244	Target Neighborhood Hits	478	Shared Neighborhood Hits	117
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI18_MOUSE
NC score	0.201717 (rank : 79)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	124
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.201413 (rank : 80)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	121
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI65_HUMAN
NC score	0.200695 (rank : 81)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	123
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI56_MOUSE
NC score	0.199861 (rank : 82)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	119
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI39_MOUSE
NC score	0.199503 (rank : 83)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	244	Target Neighborhood Hits	691	Shared Neighborhood Hits	131
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI49_HUMAN
NC score	0.199369 (rank : 84)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI62_HUMAN
NC score	0.198847 (rank : 85)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	244	Target Neighborhood Hits	584	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI39_HUMAN
NC score	0.196986 (rank : 86)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	244	Target Neighborhood Hits	693	Shared Neighborhood Hits	130
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RO52_MOUSE
NC score	0.196125 (rank : 87)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	244	Target Neighborhood Hits	360	Shared Neighborhood Hits	126
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

ZC3H5_MOUSE
NC score	0.195753 (rank : 88)	θ value	0.00665767 (rank : 23)
Query Neighborhood Hits	244	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

RN166_MOUSE
NC score	0.195518 (rank : 89)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	244	Target Neighborhood Hits	248	Shared Neighborhood Hits	119
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF39_HUMAN
NC score	0.195185 (rank : 90)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	244	Target Neighborhood Hits	200	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI35_HUMAN
NC score	0.195160 (rank : 91)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
NC score	0.195116 (rank : 92)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	244	Target Neighborhood Hits	465	Shared Neighborhood Hits	127
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RFPL2_HUMAN
NC score	0.194146 (rank : 93)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRI15_HUMAN
NC score	0.192524 (rank : 94)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	244	Target Neighborhood Hits	395	Shared Neighborhood Hits	120
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

RFPL1_HUMAN
NC score	0.190807 (rank : 95)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	78
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RN166_HUMAN
NC score	0.189194 (rank : 96)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	115
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI43_HUMAN
NC score	0.188677 (rank : 97)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	244	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI38_HUMAN
NC score	0.188623 (rank : 98)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	244	Target Neighborhood Hits	373	Shared Neighborhood Hits	124
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

ZN179_HUMAN
NC score	0.188584 (rank : 99)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI11_MOUSE
NC score	0.187811 (rank : 100)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	122
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.187406 (rank : 101)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	244	Target Neighborhood Hits	316	Shared Neighborhood Hits	122
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI17_HUMAN
NC score	0.186003 (rank : 102)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	244	Target Neighborhood Hits	318	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

RNF8_MOUSE
NC score	0.181466 (rank : 103)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	244	Target Neighborhood Hits	618	Shared Neighborhood Hits	131
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI60_MOUSE
NC score	0.181309 (rank : 104)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI17_MOUSE
NC score	0.181070 (rank : 105)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	244	Target Neighborhood Hits	620	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRIM9_HUMAN
NC score	0.180432 (rank : 106)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	244	Target Neighborhood Hits	294	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.179967 (rank : 107)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	244	Target Neighborhood Hits	274	Shared Neighborhood Hits	119
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

NHLC1_MOUSE
NC score	0.176726 (rank : 108)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	244	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_HUMAN
NC score	0.176203 (rank : 109)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN125_HUMAN
NC score	0.176151 (rank : 110)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	244	Target Neighborhood Hits	230	Shared Neighborhood Hits	111
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI46_HUMAN
NC score	0.166615 (rank : 111)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	244	Target Neighborhood Hits	291	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
NC score	0.165956 (rank : 112)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	244	Target Neighborhood Hits	287	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM2_HUMAN
NC score	0.165134 (rank : 113)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

RN152_MOUSE
NC score	0.164835 (rank : 114)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRIM3_HUMAN
NC score	0.164680 (rank : 115)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	244	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_MOUSE
NC score	0.164479 (rank : 116)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	244	Target Neighborhood Hits	331	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RN152_HUMAN
NC score	0.161522 (rank : 117)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	244	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TRIM3_MOUSE
NC score	0.161484 (rank : 118)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	244	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

ZC3H3_HUMAN
NC score	0.160297 (rank : 119)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	244	Target Neighborhood Hits	159	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

RN125_MOUSE
NC score	0.158550 (rank : 120)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	244	Target Neighborhood Hits	220	Shared Neighborhood Hits	105
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RNF8_HUMAN
NC score	0.157541 (rank : 121)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	244	Target Neighborhood Hits	622	Shared Neighborhood Hits	128
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI36_MOUSE
NC score	0.150670 (rank : 122)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	244	Target Neighborhood Hits	266	Shared Neighborhood Hits	110
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
NC score	0.150451 (rank : 123)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

MEFV_HUMAN
NC score	0.149645 (rank : 124)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	244	Target Neighborhood Hits	431	Shared Neighborhood Hits	81
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI14_MOUSE
NC score	0.148981 (rank : 125)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	244	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI14_HUMAN
NC score	0.148621 (rank : 126)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	244	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

Z3H7B_HUMAN
NC score	0.142853 (rank : 127)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

TRI42_HUMAN
NC score	0.139589 (rank : 128)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	244	Target Neighborhood Hits	283	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

PEX10_HUMAN
NC score	0.134947 (rank : 129)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	102
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RAG1_HUMAN
NC score	0.134259 (rank : 130)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	244	Target Neighborhood Hits	203	Shared Neighborhood Hits	95
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

MEFV_MOUSE
NC score	0.133824 (rank : 131)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI42_MOUSE
NC score	0.130284 (rank : 132)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	244	Target Neighborhood Hits	316	Shared Neighborhood Hits	91
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BFAR_HUMAN
NC score	0.129174 (rank : 133)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	244	Target Neighborhood Hits	222	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RAG1_MOUSE
NC score	0.128538 (rank : 134)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	244	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI37_MOUSE
NC score	0.128413 (rank : 135)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	244	Target Neighborhood Hits	316	Shared Neighborhood Hits	95
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.128284 (rank : 136)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI45_HUMAN
NC score	0.127813 (rank : 137)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI16_MOUSE
NC score	0.125080 (rank : 138)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	244	Target Neighborhood Hits	196	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BFAR_MOUSE
NC score	0.124553 (rank : 139)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	244	Target Neighborhood Hits	232	Shared Neighborhood Hits	97
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

ZC3H3_MOUSE
NC score	0.124501 (rank : 140)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	244	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ERMAP_HUMAN
NC score	0.124065 (rank : 141)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

Z3H7A_HUMAN
NC score	0.123929 (rank : 142)	θ value	0.125558 (rank : 61)
Query Neighborhood Hits	244	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

TRI45_MOUSE
NC score	0.123640 (rank : 143)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

RAD18_MOUSE
NC score	0.123493 (rank : 144)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	244	Target Neighborhood Hits	230	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRI16_HUMAN
NC score	0.121746 (rank : 145)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI44_MOUSE
NC score	0.120404 (rank : 146)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	244	Target Neighborhood Hits	327	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI44_HUMAN
NC score	0.120207 (rank : 147)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	244	Target Neighborhood Hits	393	Shared Neighborhood Hits	78
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI29_MOUSE
NC score	0.120153 (rank : 148)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	244	Target Neighborhood Hits	306	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

LNX1_MOUSE
NC score	0.119126 (rank : 149)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	244	Target Neighborhood Hits	377	Shared Neighborhood Hits	108
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

ARD1_MOUSE
NC score	0.118763 (rank : 150)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	244	Target Neighborhood Hits	573	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

LNX1_HUMAN
NC score	0.118209 (rank : 151)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	244	Target Neighborhood Hits	379	Shared Neighborhood Hits	110
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

RING1_HUMAN
NC score	0.116784 (rank : 152)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	98
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI29_HUMAN
NC score	0.116626 (rank : 153)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	244	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

LNX2_HUMAN
NC score	0.116479 (rank : 154)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	244	Target Neighborhood Hits	389	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

R113B_HUMAN
NC score	0.115826 (rank : 155)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	244	Target Neighborhood Hits	165	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

ERMAP_MOUSE
NC score	0.115756 (rank : 156)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

LNX2_MOUSE
NC score	0.115717 (rank : 157)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	244	Target Neighborhood Hits	407	Shared Neighborhood Hits	116
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

ARD1_HUMAN
NC score	0.114729 (rank : 158)	θ value	0.00869519 (rank : 24)
Query Neighborhood Hits	244	Target Neighborhood Hits	621	Shared Neighborhood Hits	78
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

RING1_MOUSE
NC score	0.114414 (rank : 159)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	244	Target Neighborhood Hits	220	Shared Neighborhood Hits	97
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

BSPRY_MOUSE
NC score	0.112541 (rank : 160)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	244	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_HUMAN
NC score	0.110393 (rank : 161)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	244	Target Neighborhood Hits	115	Shared Neighborhood Hits	55
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT3A1_HUMAN
NC score	0.110000 (rank : 162)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	244	Target Neighborhood Hits	229	Shared Neighborhood Hits	53
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
NC score	0.109892 (rank : 163)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	244	Target Neighborhood Hits	233	Shared Neighborhood Hits	52
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT1A1_MOUSE
NC score	0.108796 (rank : 164)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	244	Target Neighborhood Hits	252	Shared Neighborhood Hits	52
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_HUMAN
NC score	0.108300 (rank : 165)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	244	Target Neighborhood Hits	322	Shared Neighborhood Hits	52
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

RN123_HUMAN
NC score	0.108257 (rank : 166)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	244	Target Neighborhood Hits	175	Shared Neighborhood Hits	69
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BTNL3_HUMAN
NC score	0.108218 (rank : 167)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	244	Target Neighborhood Hits	143	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

RNF5_HUMAN
NC score	0.107462 (rank : 168)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	244	Target Neighborhood Hits	206	Shared Neighborhood Hits	91
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

BTNL9_HUMAN
NC score	0.107272 (rank : 169)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	244	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

RNF5_MOUSE
NC score	0.107039 (rank : 170)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	244	Target Neighborhood Hits	206	Shared Neighborhood Hits	89
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

HELZ_HUMAN
NC score	0.107033 (rank : 171)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

BT2A2_HUMAN
NC score	0.107000 (rank : 172)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

PML_MOUSE
NC score	0.106925 (rank : 173)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	244	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RING2_HUMAN
NC score	0.106846 (rank : 174)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	244	Target Neighborhood Hits	201	Shared Neighborhood Hits	92
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.106827 (rank : 175)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRAF4_HUMAN
NC score	0.106492 (rank : 176)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	244	Target Neighborhood Hits	373	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

R113A_HUMAN
NC score	0.106386 (rank : 177)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	244	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RNF32_HUMAN
NC score	0.106279 (rank : 178)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	244	Target Neighborhood Hits	133	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

TRAF5_MOUSE
NC score	0.105983 (rank : 179)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	244	Target Neighborhood Hits	355	Shared Neighborhood Hits	101
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

SPRY4_MOUSE
NC score	0.104463 (rank : 180)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BTNL8_HUMAN
NC score	0.104010 (rank : 181)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	244	Target Neighborhood Hits	177	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BT2A1_HUMAN
NC score	0.103722 (rank : 182)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	244	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

SPRY4_HUMAN
NC score	0.103690 (rank : 183)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	244	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

RN185_HUMAN
NC score	0.103193 (rank : 184)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	95
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.103043 (rank : 185)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	244	Target Neighborhood Hits	211	Shared Neighborhood Hits	95
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN169_HUMAN
NC score	0.102254 (rank : 186)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	244	Target Neighborhood Hits	203	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRAF7_MOUSE
NC score	0.101974 (rank : 187)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	244	Target Neighborhood Hits	470	Shared Neighborhood Hits	104
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

BT2A3_HUMAN
NC score	0.101795 (rank : 188)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	244	Target Neighborhood Hits	195	Shared Neighborhood Hits	48
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RAD18_HUMAN
NC score	0.101564 (rank : 189)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	244	Target Neighborhood Hits	284	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TRAF7_HUMAN
NC score	0.101406 (rank : 190)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	244	Target Neighborhood Hits	482	Shared Neighborhood Hits	105
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

DTX3_MOUSE
NC score	0.100341 (rank : 191)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	244	Target Neighborhood Hits	202	Shared Neighborhood Hits	90
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

UHRF1_HUMAN
NC score	0.097474 (rank : 192)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	244	Target Neighborhood Hits	272	Shared Neighborhood Hits	102
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

PZRN4_HUMAN
NC score	0.095871 (rank : 193)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	244	Target Neighborhood Hits	438	Shared Neighborhood Hits	115
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

DTX3_HUMAN
NC score	0.095533 (rank : 194)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RN146_HUMAN
NC score	0.094810 (rank : 195)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

UHRF1_MOUSE
NC score	0.094806 (rank : 196)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CHFR_HUMAN
NC score	0.094778 (rank : 197)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	244	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

SMR3B_HUMAN
NC score	0.094434 (rank : 198)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	244	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

CHFR_MOUSE
NC score	0.094199 (rank : 199)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	93
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN146_MOUSE
NC score	0.094101 (rank : 200)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	244	Target Neighborhood Hits	161	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

PML_HUMAN
NC score	0.093876 (rank : 201)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	244	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RN123_MOUSE
NC score	0.093154 (rank : 202)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	244	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

UHRF2_MOUSE
NC score	0.092117 (rank : 203)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	244	Target Neighborhood Hits	275	Shared Neighborhood Hits	107
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

UHRF2_HUMAN
NC score	0.091604 (rank : 204)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	105
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RFWD2_HUMAN
NC score	0.091354 (rank : 205)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	244	Target Neighborhood Hits	518	Shared Neighborhood Hits	116
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.090537 (rank : 206)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	244	Target Neighborhood Hits	535	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRAF5_HUMAN
NC score	0.086479 (rank : 207)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	93
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TIF1G_MOUSE
NC score	0.086081 (rank : 208)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	244	Target Neighborhood Hits	498	Shared Neighborhood Hits	102
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.085920 (rank : 209)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	244	Target Neighborhood Hits	410	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

RNF32_MOUSE
NC score	0.084222 (rank : 210)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	244	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RN141_HUMAN
NC score	0.081847 (rank : 211)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.081582 (rank : 212)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	244	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

SMRA3_HUMAN
NC score	0.081063 (rank : 213)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	244	Target Neighborhood Hits	265	Shared Neighborhood Hits	108
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

PZRN3_MOUSE
NC score	0.079401 (rank : 214)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	244	Target Neighborhood Hits	447	Shared Neighborhood Hits	108
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.078858 (rank : 215)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	244	Target Neighborhood Hits	461	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SMRA3_MOUSE
NC score	0.078302 (rank : 216)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	244	Target Neighborhood Hits	267	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

BRAP_MOUSE
NC score	0.076410 (rank : 217)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	244	Target Neighborhood Hits	409	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

TIF1B_HUMAN
NC score	0.075981 (rank : 218)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	244	Target Neighborhood Hits	312	Shared Neighborhood Hits	77
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.074936 (rank : 219)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	74
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

SIAH2_HUMAN
NC score	0.071628 (rank : 220)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	244	Target Neighborhood Hits	94	Shared Neighborhood Hits	42
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

BIRC7_HUMAN
NC score	0.071083 (rank : 221)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	244	Target Neighborhood Hits	185	Shared Neighborhood Hits	96
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CM007_MOUSE
NC score	0.070800 (rank : 222)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	244	Target Neighborhood Hits	416	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

SIAH2_MOUSE
NC score	0.070415 (rank : 223)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	244	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TRAF3_MOUSE
NC score	0.069513 (rank : 224)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	244	Target Neighborhood Hits	476	Shared Neighborhood Hits	92
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF3_HUMAN
NC score	0.069333 (rank : 225)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	244	Target Neighborhood Hits	463	Shared Neighborhood Hits	91
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF2_MOUSE
NC score	0.068388 (rank : 226)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	244	Target Neighborhood Hits	394	Shared Neighborhood Hits	88
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF4_MOUSE
NC score	0.068152 (rank : 227)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	244	Target Neighborhood Hits	338	Shared Neighborhood Hits	65
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

BRAP_HUMAN
NC score	0.067598 (rank : 228)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	244	Target Neighborhood Hits	560	Shared Neighborhood Hits	44
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

TRAF2_HUMAN
NC score	0.066978 (rank : 229)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	244	Target Neighborhood Hits	402	Shared Neighborhood Hits	85
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

CM007_HUMAN
NC score	0.061483 (rank : 230)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	244	Target Neighborhood Hits	422	Shared Neighborhood Hits	74
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

ATX2L_MOUSE
NC score	0.060860 (rank : 231)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	244	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

PCGF6_MOUSE
NC score	0.059671 (rank : 232)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	244	Target Neighborhood Hits	163	Shared Neighborhood Hits	72
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_HUMAN
NC score	0.058927 (rank : 233)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

UB7I3_MOUSE
NC score	0.057541 (rank : 234)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	244	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

TOPRS_MOUSE
NC score	0.055579 (rank : 235)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	244	Target Neighborhood Hits	263	Shared Neighborhood Hits	65
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.055414 (rank : 236)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	244	Target Neighborhood Hits	286	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CBL_MOUSE
NC score	0.054947 (rank : 237)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	244	Target Neighborhood Hits	426	Shared Neighborhood Hits	92
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TIF1A_HUMAN
NC score	0.053509 (rank : 238)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	244	Target Neighborhood Hits	327	Shared Neighborhood Hits	77
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

AMFR2_HUMAN
NC score	0.051301 (rank : 239)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
NC score	0.051038 (rank : 240)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	244	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ZC11A_MOUSE
NC score	0.048751 (rank : 241)	θ value	0.0431538 (rank : 41)
Query Neighborhood Hits	244	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

HM20A_HUMAN
NC score	0.046833 (rank : 242)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	244	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.046487 (rank : 243)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	244	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

ZN645_HUMAN
NC score	0.044485 (rank : 244)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	244	Target Neighborhood Hits	265	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

RAI2_HUMAN
NC score	0.044286 (rank : 245)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5P3, Q8N6X7	Gene names	RAI2
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 2.

MBD6_HUMAN
NC score	0.042946 (rank : 246)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	244	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MLL3_HUMAN
NC score	0.042505 (rank : 247)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	244	Target Neighborhood Hits	1644	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CN037_MOUSE
NC score	0.042433 (rank : 248)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	244	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

TRI66_HUMAN
NC score	0.042061 (rank : 249)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	244	Target Neighborhood Hits	479	Shared Neighborhood Hits	58
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RMD5B_HUMAN
NC score	0.041213 (rank : 250)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	244	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96G75, Q6UVY7, Q9H6F6	Gene names	RMND5B
Domain Architecture
Description	RMD5 homolog B.

MLL3_MOUSE
NC score	0.041105 (rank : 251)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	244	Target Neighborhood Hits	1399	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

HM20B_HUMAN
NC score	0.040513 (rank : 252)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

RMD5B_MOUSE
NC score	0.040437 (rank : 253)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	244	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YQ7	Gene names	Rmnd5b
Domain Architecture
Description	RMD5 homolog B.

ATX2L_HUMAN
NC score	0.039053 (rank : 254)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	244	Target Neighborhood Hits	443	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

REPS2_MOUSE
NC score	0.038547 (rank : 255)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

SSXT_MOUSE
NC score	0.038262 (rank : 256)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	244	Target Neighborhood Hits	118	Shared Neighborhood Hits	13
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

MCA1_HUMAN
NC score	0.036323 (rank : 257)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	244	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q12904, Q6FG28, Q96CQ9	Gene names	SCYE1, EMAP2
Domain Architecture
Description	Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)].

SSXT_HUMAN
NC score	0.035935 (rank : 258)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	244	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

PHC1_MOUSE
NC score	0.035765 (rank : 259)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	244	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

RERE_MOUSE
NC score	0.034855 (rank : 260)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	244	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MNT_MOUSE
NC score	0.034384 (rank : 261)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	244	Target Neighborhood Hits	432	Shared Neighborhood Hits	24
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NFX1_HUMAN
NC score	0.033570 (rank : 262)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	244	Target Neighborhood Hits	405	Shared Neighborhood Hits	11
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

VCIP1_HUMAN
NC score	0.032915 (rank : 263)	θ value	1.38821 (rank : 131)
Query Neighborhood Hits	244	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_MOUSE
NC score	0.031195 (rank : 264)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	244	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

HGS_MOUSE
NC score	0.030241 (rank : 265)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	244	Target Neighborhood Hits	589	Shared Neighborhood Hits	35
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HM20B_MOUSE
NC score	0.030057 (rank : 266)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	244	Target Neighborhood Hits	122	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

ZN750_HUMAN
NC score	0.029109 (rank : 267)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	244	Target Neighborhood Hits	183	Shared Neighborhood Hits	8
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

HGS_HUMAN
NC score	0.028119 (rank : 268)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	244	Target Neighborhood Hits	517	Shared Neighborhood Hits	32
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

BCLF1_HUMAN
NC score	0.027258 (rank : 269)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

USH1C_MOUSE
NC score	0.027212 (rank : 270)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	244	Target Neighborhood Hits	557	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

MCA1_MOUSE
NC score	0.026414 (rank : 271)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	244	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	P31230, Q60659	Gene names	Scye1, Emap2
Domain Architecture
Description	Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)].

FUBP2_HUMAN
NC score	0.025962 (rank : 272)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	244	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

RIN3_MOUSE
NC score	0.024137 (rank : 273)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	244	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

PABP1_HUMAN
NC score	0.023055 (rank : 274)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
NC score	0.022973 (rank : 275)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	7
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

ZFY21_MOUSE
NC score	0.022848 (rank : 276)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	244	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

KTN1_HUMAN
NC score	0.022789 (rank : 277)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	244	Target Neighborhood Hits	1197	Shared Neighborhood Hits	41
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

FOXK1_MOUSE
NC score	0.020876 (rank : 278)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	244	Target Neighborhood Hits	215	Shared Neighborhood Hits	7
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

PABP3_HUMAN
NC score	0.020315 (rank : 279)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	244	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H361, Q8NHV0, Q9H086	Gene names	PABPC3, PABP3, PABPL3
Domain Architecture
Description	Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP 3) (Testis-specific poly(A)-binding protein).

RGS3_MOUSE
NC score	0.019926 (rank : 280)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	244	Target Neighborhood Hits	1621	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZIM10_HUMAN
NC score	0.019308 (rank : 281)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	244	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

STMN4_HUMAN
NC score	0.019245 (rank : 282)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	244	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.019241 (rank : 283)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	244	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

ZC313_HUMAN
NC score	0.019157 (rank : 284)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	244	Target Neighborhood Hits	772	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ANFY1_MOUSE
NC score	0.019013 (rank : 285)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	244	Target Neighborhood Hits	480	Shared Neighborhood Hits	13
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

DACT1_HUMAN
NC score	0.018314 (rank : 286)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	244	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

TRM1_HUMAN
NC score	0.018059 (rank : 287)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	244	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

ANFY1_HUMAN
NC score	0.016960 (rank : 288)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	244	Target Neighborhood Hits	480	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BAZ2A_HUMAN
NC score	0.016441 (rank : 289)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	244	Target Neighborhood Hits	780	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

GGEE2_HUMAN
NC score	0.016416 (rank : 290)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	244	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2X7, Q5JRK7, Q5JRK8	Gene names	PAGE2, GAGEE2
Domain Architecture	No domain graphic available
Description	G antigen family E member 2 (Prostate-associated gene 2 protein) (PAGE-2).

RGS3_HUMAN
NC score	0.016221 (rank : 291)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	244	Target Neighborhood Hits	1375	Shared Neighborhood Hits	44
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CEL_HUMAN
NC score	0.015592 (rank : 292)	θ value	1.06291 (rank : 117)
Query Neighborhood Hits	244	Target Neighborhood Hits	896	Shared Neighborhood Hits	25
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

6PGL_MOUSE
NC score	0.015575 (rank : 293)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	244	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQ60, Q3TA62	Gene names	Pgls
Domain Architecture	No domain graphic available
Description	6-phosphogluconolactonase (EC 3.1.1.31) (6PGL).

MIRO2_MOUSE
NC score	0.015453 (rank : 294)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	244	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZN7	Gene names	Rhot2, Arht2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (Ras homolog gene family member T2).

LPP_HUMAN
NC score	0.015363 (rank : 295)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	244	Target Neighborhood Hits	775	Shared Neighborhood Hits	28
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

FGD6_HUMAN
NC score	0.015015 (rank : 296)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	244	Target Neighborhood Hits	237	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

IF4G2_HUMAN
NC score	0.014876 (rank : 297)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	244	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

FGD6_MOUSE
NC score	0.014804 (rank : 298)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

PCNT_HUMAN
NC score	0.014268 (rank : 299)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	244	Target Neighborhood Hits	1551	Shared Neighborhood Hits	56
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

MACF1_MOUSE
NC score	0.013766 (rank : 300)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	244	Target Neighborhood Hits	1313	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

HG2A_MOUSE
NC score	0.013720 (rank : 301)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

ETV5_MOUSE
NC score	0.013440 (rank : 302)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	244	Target Neighborhood Hits	328	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

IF4G2_MOUSE
NC score	0.012979 (rank : 303)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	244	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

OPTN_MOUSE
NC score	0.012125 (rank : 304)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	244	Target Neighborhood Hits	1120	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TPR_HUMAN
NC score	0.011779 (rank : 305)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	244	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

IL3RB_MOUSE
NC score	0.011504 (rank : 306)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	244	Target Neighborhood Hits	355	Shared Neighborhood Hits	14
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

SNX19_HUMAN
NC score	0.011431 (rank : 307)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	244	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

ARHG1_MOUSE
NC score	0.008698 (rank : 308)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	244	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ATS14_HUMAN
NC score	0.008430 (rank : 309)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

HAP1_HUMAN
NC score	0.008267 (rank : 310)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	244	Target Neighborhood Hits	606	Shared Neighborhood Hits	26
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

ETV6_HUMAN
NC score	0.008224 (rank : 311)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

MDC1_HUMAN
NC score	0.008093 (rank : 312)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	244	Target Neighborhood Hits	1446	Shared Neighborhood Hits	34
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TACC2_MOUSE
NC score	0.007889 (rank : 313)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	244	Target Neighborhood Hits	774	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

DOK1_MOUSE
NC score	0.007048 (rank : 314)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

NOTC2_HUMAN
NC score	0.006715 (rank : 315)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	244	Target Neighborhood Hits	1113	Shared Neighborhood Hits	17
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

COHA1_HUMAN
NC score	0.005840 (rank : 316)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	244	Target Neighborhood Hits	400	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

LYAG_MOUSE
NC score	0.005536 (rank : 317)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	244	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).

SI1L3_HUMAN
NC score	0.005049 (rank : 318)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	244	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

BAI2_HUMAN
NC score	0.004270 (rank : 319)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	244	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TBX21_MOUSE
NC score	0.004242 (rank : 320)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	244	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

RP3A_MOUSE
NC score	0.003943 (rank : 321)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	244	Target Neighborhood Hits	510	Shared Neighborhood Hits	15
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TTK_MOUSE
NC score	0.003775 (rank : 322)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	244	Target Neighborhood Hits	803	Shared Neighborhood Hits	9
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

PDLI7_HUMAN
NC score	0.003729 (rank : 323)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	244	Target Neighborhood Hits	547	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

ZN281_HUMAN
NC score	0.003544 (rank : 324)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	244	Target Neighborhood Hits	745	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2X9, Q9NY92	Gene names	ZNF281, GZP1, ZBP99
Domain Architecture	No domain graphic available
Description	Zinc finger protein 281 (Zinc finger DNA-binding protein 99) (Transcription factor ZBP-99) (GC-box-binding zinc finger protein 1).

LRFN2_MOUSE
NC score	0.002833 (rank : 325)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	244	Target Neighborhood Hits	450	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

SUHW4_MOUSE
NC score	0.001917 (rank : 326)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	244	Target Neighborhood Hits	737	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ZN516_MOUSE
NC score	0.001461 (rank : 327)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	244	Target Neighborhood Hits	1197	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CRUM1_HUMAN
NC score	0.001408 (rank : 328)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	244	Target Neighborhood Hits	457	Shared Neighborhood Hits	3
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

MYO5B_HUMAN
NC score	0.001355 (rank : 329)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	244	Target Neighborhood Hits	911	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

CD2L1_MOUSE
NC score	0.000297 (rank : 330)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	244	Target Neighborhood Hits	1463	Shared Neighborhood Hits	26
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

MAST4_HUMAN
NC score	-0.000594 (rank : 331)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	244	Target Neighborhood Hits	1804	Shared Neighborhood Hits	35
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

EGR4_HUMAN
NC score	-0.000670 (rank : 332)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	244	Target Neighborhood Hits	939	Shared Neighborhood Hits	15
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

CD2L1_HUMAN
NC score	-0.000920 (rank : 333)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	244	Target Neighborhood Hits	1467	Shared Neighborhood Hits	29
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

GP176_MOUSE
NC score	-0.000977 (rank : 334)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	244	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

CD2L2_HUMAN
NC score	-0.001118 (rank : 335)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	244	Target Neighborhood Hits	1439	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

SIP1_HUMAN
NC score	-0.001538 (rank : 336)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	244	Target Neighborhood Hits	832	Shared Neighborhood Hits	12
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

STK3_MOUSE
NC score	-0.001828 (rank : 337)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	244	Target Neighborhood Hits	869	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).