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Network neighborhood for query Sequence : ERMAP_HUMAN

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ERMAP_HUMAN
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERMAP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	155
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	4.72459e-150 (rank : 2)	NC score	0.977480 (rank : 2)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

MEFV_HUMAN
θ value	3.974e-56 (rank : 3)	NC score	0.888785 (rank : 16)
Query Neighborhood Hits	155	Target Neighborhood Hits	431	Shared Neighborhood Hits	80
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

BT1A1_MOUSE
θ value	5.19021e-56 (rank : 4)	NC score	0.931285 (rank : 10)
Query Neighborhood Hits	155	Target Neighborhood Hits	252	Shared Neighborhood Hits	116
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
θ value	9.78833e-55 (rank : 5)	NC score	0.936988 (rank : 6)
Query Neighborhood Hits	155	Target Neighborhood Hits	233	Shared Neighborhood Hits	107
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

TRI27_HUMAN
θ value	3.1488e-53 (rank : 6)	NC score	0.871421 (rank : 18)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	80
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	3.1488e-53 (rank : 7)	NC score	0.872741 (rank : 17)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	80
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

BT2A2_HUMAN
θ value	7.01481e-53 (rank : 8)	NC score	0.949282 (rank : 4)
Query Neighborhood Hits	155	Target Neighborhood Hits	191	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI39_MOUSE
θ value	1.46268e-50 (rank : 9)	NC score	0.830339 (rank : 35)
Query Neighborhood Hits	155	Target Neighborhood Hits	691	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
θ value	4.25575e-50 (rank : 10)	NC score	0.828014 (rank : 36)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

BT1A1_HUMAN
θ value	9.48078e-50 (rank : 11)	NC score	0.922868 (rank : 11)
Query Neighborhood Hits	155	Target Neighborhood Hits	322	Shared Neighborhood Hits	106
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BTNL9_HUMAN
θ value	4.70527e-49 (rank : 12)	NC score	0.951806 (rank : 3)
Query Neighborhood Hits	155	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

RO52_HUMAN
θ value	6.14528e-49 (rank : 13)	NC score	0.844771 (rank : 29)
Query Neighborhood Hits	155	Target Neighborhood Hits	419	Shared Neighborhood Hits	80
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI68_HUMAN
θ value	3.72821e-46 (rank : 14)	NC score	0.868141 (rank : 19)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	80
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

BT3A1_HUMAN
θ value	1.73182e-43 (rank : 15)	NC score	0.935872 (rank : 8)
Query Neighborhood Hits	155	Target Neighborhood Hits	229	Shared Neighborhood Hits	108
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TRI11_HUMAN
θ value	6.58091e-43 (rank : 16)	NC score	0.856509 (rank : 24)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	80
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI68_MOUSE
θ value	1.12253e-42 (rank : 17)	NC score	0.861335 (rank : 20)
Query Neighborhood Hits	155	Target Neighborhood Hits	356	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI11_MOUSE
θ value	7.27602e-42 (rank : 18)	NC score	0.859899 (rank : 21)
Query Neighborhood Hits	155	Target Neighborhood Hits	329	Shared Neighborhood Hits	81
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

BT2A1_HUMAN
θ value	1.2411e-41 (rank : 19)	NC score	0.940728 (rank : 5)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	108
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

RO52_MOUSE
θ value	4.71619e-41 (rank : 20)	NC score	0.848297 (rank : 28)
Query Neighborhood Hits	155	Target Neighborhood Hits	360	Shared Neighborhood Hits	81
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI62_HUMAN
θ value	2.58786e-39 (rank : 21)	NC score	0.821606 (rank : 39)
Query Neighborhood Hits	155	Target Neighborhood Hits	584	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	4.41421e-39 (rank : 22)	NC score	0.836442 (rank : 33)
Query Neighborhood Hits	155	Target Neighborhood Hits	478	Shared Neighborhood Hits	80
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

BT2A3_HUMAN
θ value	1.08726e-37 (rank : 23)	NC score	0.933659 (rank : 9)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	110
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

TRI38_HUMAN
θ value	1.42001e-37 (rank : 24)	NC score	0.849791 (rank : 26)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	80
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

BTNL8_HUMAN
θ value	5.0505e-35 (rank : 25)	NC score	0.921753 (rank : 12)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	102
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL3_HUMAN
θ value	6.59618e-35 (rank : 26)	NC score	0.936441 (rank : 7)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	94
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRIM7_HUMAN
θ value	1.79631e-32 (rank : 27)	NC score	0.848551 (rank : 27)
Query Neighborhood Hits	155	Target Neighborhood Hits	336	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI50_MOUSE
θ value	3.06405e-32 (rank : 28)	NC score	0.796289 (rank : 47)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	80
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
θ value	1.52067e-31 (rank : 29)	NC score	0.793694 (rank : 48)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	80
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM7_MOUSE
θ value	2.59387e-31 (rank : 30)	NC score	0.840483 (rank : 30)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	80
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI60_HUMAN
θ value	4.89182e-30 (rank : 31)	NC score	0.837359 (rank : 32)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	80
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

RFPL3_HUMAN
θ value	3.17079e-29 (rank : 32)	NC score	0.908442 (rank : 14)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL2_HUMAN
θ value	5.40856e-29 (rank : 33)	NC score	0.905312 (rank : 15)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRIM6_HUMAN
θ value	3.50572e-28 (rank : 34)	NC score	0.805721 (rank : 43)
Query Neighborhood Hits	155	Target Neighborhood Hits	412	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

RFPL1_HUMAN
θ value	5.97985e-28 (rank : 35)	NC score	0.912070 (rank : 13)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI41_HUMAN
θ value	7.80994e-28 (rank : 36)	NC score	0.854920 (rank : 25)
Query Neighborhood Hits	155	Target Neighborhood Hits	349	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI60_MOUSE
θ value	1.02001e-27 (rank : 37)	NC score	0.857901 (rank : 22)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI15_HUMAN
θ value	6.61148e-27 (rank : 38)	NC score	0.837891 (rank : 31)
Query Neighborhood Hits	155	Target Neighborhood Hits	395	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM6_MOUSE
θ value	1.12775e-26 (rank : 39)	NC score	0.797025 (rank : 46)
Query Neighborhood Hits	155	Target Neighborhood Hits	451	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI10_MOUSE
θ value	7.30988e-26 (rank : 40)	NC score	0.824104 (rank : 38)
Query Neighborhood Hits	155	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI17_MOUSE
θ value	7.30988e-26 (rank : 41)	NC score	0.804462 (rank : 44)
Query Neighborhood Hits	155	Target Neighborhood Hits	620	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI17_HUMAN
θ value	1.24688e-25 (rank : 42)	NC score	0.835684 (rank : 34)
Query Neighborhood Hits	155	Target Neighborhood Hits	318	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI10_HUMAN
θ value	4.73814e-25 (rank : 43)	NC score	0.816080 (rank : 40)
Query Neighborhood Hits	155	Target Neighborhood Hits	315	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

MOG_MOUSE
θ value	6.40375e-22 (rank : 44)	NC score	0.495116 (rank : 83)
Query Neighborhood Hits	155	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

TRI34_HUMAN
θ value	1.5773e-20 (rank : 45)	NC score	0.780027 (rank : 52)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RNF39_HUMAN
θ value	1.02238e-19 (rank : 46)	NC score	0.857339 (rank : 23)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

MOG_HUMAN
θ value	2.5182e-18 (rank : 47)	NC score	0.494914 (rank : 84)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	32
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

TRI14_HUMAN
θ value	3.28887e-18 (rank : 48)	NC score	0.815756 (rank : 41)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI22_HUMAN
θ value	5.60996e-18 (rank : 49)	NC score	0.764259 (rank : 58)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI14_MOUSE
θ value	2.13179e-17 (rank : 50)	NC score	0.824242 (rank : 37)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRIM4_HUMAN
θ value	4.74913e-17 (rank : 51)	NC score	0.805890 (rank : 42)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM5_HUMAN
θ value	1.058e-16 (rank : 52)	NC score	0.774620 (rank : 55)
Query Neighborhood Hits	155	Target Neighborhood Hits	424	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI26_MOUSE
θ value	6.85773e-16 (rank : 53)	NC score	0.751341 (rank : 62)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	80
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

BTNL1_MOUSE
θ value	4.44505e-15 (rank : 54)	NC score	0.495144 (rank : 82)
Query Neighborhood Hits	155	Target Neighborhood Hits	151	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

TRI26_HUMAN
θ value	7.58209e-15 (rank : 55)	NC score	0.757712 (rank : 60)
Query Neighborhood Hits	155	Target Neighborhood Hits	335	Shared Neighborhood Hits	78
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI18_HUMAN
θ value	1.29331e-14 (rank : 56)	NC score	0.569135 (rank : 73)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI43_HUMAN
θ value	1.68911e-14 (rank : 57)	NC score	0.781049 (rank : 51)
Query Neighborhood Hits	155	Target Neighborhood Hits	341	Shared Neighborhood Hits	78
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI35_HUMAN
θ value	2.20605e-14 (rank : 58)	NC score	0.771544 (rank : 56)
Query Neighborhood Hits	155	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI34_MOUSE
θ value	4.91457e-14 (rank : 59)	NC score	0.790405 (rank : 49)
Query Neighborhood Hits	155	Target Neighborhood Hits	332	Shared Neighborhood Hits	80
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI49_HUMAN
θ value	6.41864e-14 (rank : 60)	NC score	0.800042 (rank : 45)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI35_MOUSE
θ value	1.86753e-13 (rank : 61)	NC score	0.757176 (rank : 61)
Query Neighborhood Hits	155	Target Neighborhood Hits	465	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI48_HUMAN
θ value	1.86753e-13 (rank : 62)	NC score	0.781788 (rank : 50)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

BTNL2_HUMAN
θ value	2.43908e-13 (rank : 63)	NC score	0.478002 (rank : 89)
Query Neighborhood Hits	155	Target Neighborhood Hits	164	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

TRI18_MOUSE
θ value	1.58096e-12 (rank : 64)	NC score	0.543274 (rank : 77)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	82
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRIM1_MOUSE
θ value	2.69671e-12 (rank : 65)	NC score	0.510772 (rank : 80)
Query Neighborhood Hits	155	Target Neighborhood Hits	361	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM1_HUMAN
θ value	3.52202e-12 (rank : 66)	NC score	0.511316 (rank : 79)
Query Neighborhood Hits	155	Target Neighborhood Hits	345	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI25_MOUSE
θ value	7.84624e-12 (rank : 67)	NC score	0.608635 (rank : 68)
Query Neighborhood Hits	155	Target Neighborhood Hits	446	Shared Neighborhood Hits	80
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

SPRY4_MOUSE
θ value	5.08577e-11 (rank : 68)	NC score	0.779473 (rank : 53)
Query Neighborhood Hits	155	Target Neighborhood Hits	82	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI25_HUMAN
θ value	8.67504e-11 (rank : 69)	NC score	0.623155 (rank : 66)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	80
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

SPRY4_HUMAN
θ value	3.29651e-10 (rank : 70)	NC score	0.763020 (rank : 59)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI16_HUMAN
θ value	4.30538e-10 (rank : 71)	NC score	0.681163 (rank : 64)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	74
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BT3A2_HUMAN
θ value	1.25267e-09 (rank : 72)	NC score	0.488052 (rank : 85)
Query Neighborhood Hits	155	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

TRI16_MOUSE
θ value	3.64472e-09 (rank : 73)	NC score	0.672030 (rank : 65)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	75
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BSPRY_HUMAN
θ value	5.26297e-08 (rank : 74)	NC score	0.776952 (rank : 54)
Query Neighborhood Hits	155	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	5.26297e-08 (rank : 75)	NC score	0.770671 (rank : 57)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI30_MOUSE
θ value	5.26297e-08 (rank : 76)	NC score	0.729366 (rank : 63)
Query Neighborhood Hits	155	Target Neighborhood Hits	434	Shared Neighborhood Hits	80
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

CD276_HUMAN
θ value	1.69304e-06 (rank : 77)	NC score	0.287800 (rank : 127)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	3.77169e-06 (rank : 78)	NC score	0.310621 (rank : 119)
Query Neighborhood Hits	155	Target Neighborhood Hits	243	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

TRI65_MOUSE
θ value	4.1701e-05 (rank : 79)	NC score	0.613508 (rank : 67)
Query Neighborhood Hits	155	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

PDL1_MOUSE
θ value	0.00228821 (rank : 80)	NC score	0.259043 (rank : 133)
Query Neighborhood Hits	155	Target Neighborhood Hits	168	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

TRI65_HUMAN
θ value	0.00390308 (rank : 81)	NC score	0.606947 (rank : 69)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

SIGL5_HUMAN
θ value	0.0113563 (rank : 82)	NC score	0.037852 (rank : 297)
Query Neighborhood Hits	155	Target Neighborhood Hits	246	Shared Neighborhood Hits	36
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

PDL1_HUMAN
θ value	0.0148317 (rank : 83)	NC score	0.215534 (rank : 149)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

HPLN3_MOUSE
θ value	0.0330416 (rank : 84)	NC score	0.063723 (rank : 270)
Query Neighborhood Hits	155	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

JAML1_HUMAN
θ value	0.0330416 (rank : 85)	NC score	0.055315 (rank : 278)
Query Neighborhood Hits	155	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

JAML1_MOUSE
θ value	0.0330416 (rank : 86)	NC score	0.087202 (rank : 235)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	32
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

HPLN3_HUMAN
θ value	0.0563607 (rank : 87)	NC score	0.044509 (rank : 295)
Query Neighborhood Hits	155	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

TPSNR_MOUSE
θ value	0.0736092 (rank : 88)	NC score	0.121539 (rank : 208)
Query Neighborhood Hits	155	Target Neighborhood Hits	336	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

CEAM6_HUMAN
θ value	0.0961366 (rank : 89)	NC score	0.020323 (rank : 322)
Query Neighborhood Hits	155	Target Neighborhood Hits	308	Shared Neighborhood Hits	32
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

HHLA2_HUMAN
θ value	0.0961366 (rank : 90)	NC score	0.246707 (rank : 138)
Query Neighborhood Hits	155	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

CD47_MOUSE
θ value	0.125558 (rank : 91)	NC score	0.029365 (rank : 302)
Query Neighborhood Hits	155	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q61735, Q921Z2	Gene names	Cd47
Domain Architecture	No domain graphic available
Description	Leukocyte surface antigen CD47 precursor (Integrin-associated protein) (IAP).

TITIN_HUMAN
θ value	0.279714 (rank : 92)	NC score	0.014186 (rank : 332)
Query Neighborhood Hits	155	Target Neighborhood Hits	2923	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CD86_MOUSE
θ value	0.365318 (rank : 93)	NC score	0.211967 (rank : 151)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CSPG2_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.034570 (rank : 300)
Query Neighborhood Hits	155	Target Neighborhood Hits	681	Shared Neighborhood Hits	30
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

SIGL8_HUMAN
θ value	0.47712 (rank : 95)	NC score	0.021023 (rank : 317)
Query Neighborhood Hits	155	Target Neighborhood Hits	252	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

TPSNR_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.079121 (rank : 249)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BX59, Q9NWB8	Gene names	TAPBPL
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

TRI46_MOUSE
θ value	0.47712 (rank : 97)	NC score	0.324448 (rank : 114)
Query Neighborhood Hits	155	Target Neighborhood Hits	287	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

HV17_MOUSE
θ value	0.62314 (rank : 98)	NC score	0.019221 (rank : 327)
Query Neighborhood Hits	155	Target Neighborhood Hits	238	Shared Neighborhood Hits	21
SwissProt Accessions	P01786	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region MOPC 47A.

HPLN2_MOUSE
θ value	0.813845 (rank : 99)	NC score	0.045927 (rank : 293)
Query Neighborhood Hits	155	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HV18_MOUSE
θ value	0.813845 (rank : 100)	NC score	0.021046 (rank : 315)
Query Neighborhood Hits	155	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	P01787	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V regions TEPC 15/S107/HPCM1/HPCM2/HPCM3.

HV19_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.021250 (rank : 314)
Query Neighborhood Hits	155	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	P01788	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region H8.

HV22_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.021039 (rank : 316)
Query Neighborhood Hits	155	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	P01791	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region HPCM6.

TREM1_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.033144 (rank : 301)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JKE2, Q3TAL7	Gene names	Trem1
Domain Architecture	No domain graphic available
Description	Triggering receptor expressed on myeloid cells 1 precursor (TREM-1).

HV20_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.020410 (rank : 321)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	22
SwissProt Accessions	P01789	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region M603.

NEO1_MOUSE
θ value	1.06291 (rank : 105)	NC score	0.014104 (rank : 333)
Query Neighborhood Hits	155	Target Neighborhood Hits	523	Shared Neighborhood Hits	33
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

CD86_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.221316 (rank : 146)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

HPLN1_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.035626 (rank : 298)
Query Neighborhood Hits	155	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

TRI46_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.324057 (rank : 115)
Query Neighborhood Hits	155	Target Neighborhood Hits	291	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI47_MOUSE
θ value	1.38821 (rank : 109)	NC score	0.500852 (rank : 81)
Query Neighborhood Hits	155	Target Neighborhood Hits	295	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

HV23_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.019572 (rank : 325)
Query Neighborhood Hits	155	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	P01792	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region HPCG8.

HV25_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.020040 (rank : 323)
Query Neighborhood Hits	155	Target Neighborhood Hits	216	Shared Neighborhood Hits	22
SwissProt Accessions	P01794	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region HPCG14.

HV27_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.028190 (rank : 305)
Query Neighborhood Hits	155	Target Neighborhood Hits	202	Shared Neighborhood Hits	26
SwissProt Accessions	P01796	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region A4.

HV28_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.028362 (rank : 304)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	P01797	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region U61.

HV32_MOUSE
θ value	1.81305 (rank : 114)	NC score	0.028093 (rank : 306)
Query Neighborhood Hits	155	Target Neighborhood Hits	204	Shared Neighborhood Hits	26
SwissProt Accessions	P01801	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region J606.

HV34_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.028410 (rank : 303)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	26
SwissProt Accessions	P01803	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region AMPC1.

HV3T_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.021320 (rank : 313)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	P01781	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region GAL.

TIMD3_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.080302 (rank : 244)
Query Neighborhood Hits	155	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VIM0	Gene names	Havcr2, Tim3, Timd3
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 2 homolog precursor (HAVcr-2) (T cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T cell membrane protein 3) (TIM-3).

TRI47_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.480857 (rank : 88)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	80
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRIM9_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.331115 (rank : 110)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

CD33_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.020709 (rank : 319)
Query Neighborhood Hits	155	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	P20138, Q8TD24	Gene names	CD33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3) (gp67).

CD80_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.128065 (rank : 199)
Query Neighborhood Hits	155	Target Neighborhood Hits	129	Shared Neighborhood Hits	31
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

PIGR_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.054058 (rank : 279)
Query Neighborhood Hits	155	Target Neighborhood Hits	214	Shared Neighborhood Hits	32
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

VCAM1_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.020525 (rank : 320)
Query Neighborhood Hits	155	Target Neighborhood Hits	352	Shared Neighborhood Hits	32
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

HPLN1_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.039111 (rank : 296)
Query Neighborhood Hits	155	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

ILRL1_MOUSE
θ value	3.0926 (rank : 125)	NC score	0.006745 (rank : 342)
Query Neighborhood Hits	155	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

HV3K_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.019464 (rank : 326)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	25
SwissProt Accessions	P01772	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region KOL.

IRPL1_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.012859 (rank : 334)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

KIRR2_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.012329 (rank : 335)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

SLAF5_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.017021 (rank : 329)
Query Neighborhood Hits	155	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	Q18PI6, Q18PI7, Q3TBT1, Q3U0A2, Q8BFV0, Q9Z178	Gene names	Cd84, Slamf5
Domain Architecture	No domain graphic available
Description	SLAM family member 5 precursor (Signaling lymphocytic activation molecule 5) (Leukocyte differentiation antigen CD84) (CD84 antigen).

CEAM1_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.012126 (rank : 336)
Query Neighborhood Hits	155	Target Neighborhood Hits	348	Shared Neighborhood Hits	31
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CSPG2_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.021612 (rank : 311)
Query Neighborhood Hits	155	Target Neighborhood Hits	711	Shared Neighborhood Hits	23
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HV21_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.020834 (rank : 318)
Query Neighborhood Hits	155	Target Neighborhood Hits	229	Shared Neighborhood Hits	22
SwissProt Accessions	P01790	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region M511.

HV31_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.022816 (rank : 310)
Query Neighborhood Hits	155	Target Neighborhood Hits	176	Shared Neighborhood Hits	24
SwissProt Accessions	P01800	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region T957.

PVRL2_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.021554 (rank : 312)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	23
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

TIMD3_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.090214 (rank : 232)
Query Neighborhood Hits	155	Target Neighborhood Hits	62	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDQ0, Q8WW60, Q96K94	Gene names	HAVCR2, TIM3, TIMD3
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 2 precursor (HAVcr-2) (T cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T cell membrane protein 3) (TIM-3).

CD80_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.138907 (rank : 190)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

CDON_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.011138 (rank : 338)
Query Neighborhood Hits	155	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

HV26_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.017924 (rank : 328)
Query Neighborhood Hits	155	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P01795	Gene names
Domain Architecture
Description	Ig heavy chain V region M167 precursor.

HV29_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.024724 (rank : 307)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	P01798	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region E109.

LY9_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.008675 (rank : 339)
Query Neighborhood Hits	155	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBG7, Q14775, Q5VYI3, Q9H4N5, Q9NQ24	Gene names	LY9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9) (CD229 antigen).

PIGR_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.045857 (rank : 294)
Query Neighborhood Hits	155	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

TRIM9_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.317051 (rank : 117)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

UTRO_HUMAN
θ value	6.88961 (rank : 143)	NC score	-0.002077 (rank : 343)
Query Neighborhood Hits	155	Target Neighborhood Hits	960	Shared Neighborhood Hits	5
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

VSIG4_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.053905 (rank : 280)
Query Neighborhood Hits	155	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

DCC_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.014876 (rank : 331)
Query Neighborhood Hits	155	Target Neighborhood Hits	583	Shared Neighborhood Hits	41
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DZIP1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.007236 (rank : 341)
Query Neighborhood Hits	155	Target Neighborhood Hits	530	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

HPLN2_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.035163 (rank : 299)
Query Neighborhood Hits	155	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HV30_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.023088 (rank : 309)
Query Neighborhood Hits	155	Target Neighborhood Hits	216	Shared Neighborhood Hits	25
SwissProt Accessions	P01799	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region ABE-47N.

HV33_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.023586 (rank : 308)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	P01802	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region W3082.

ICAM5_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.008080 (rank : 340)
Query Neighborhood Hits	155	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

KIRR2_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.011907 (rank : 337)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

PDL2_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.198069 (rank : 162)
Query Neighborhood Hits	155	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

SIGL6_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.019908 (rank : 324)
Query Neighborhood Hits	155	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SIGL7_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.016232 (rank : 330)
Query Neighborhood Hits	155	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

TRI36_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.292604 (rank : 124)
Query Neighborhood Hits	155	Target Neighborhood Hits	266	Shared Neighborhood Hits	79
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

AMFR2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.084510 (rank : 238)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.084919 (rank : 237)
Query Neighborhood Hits	155	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARD1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.073606 (rank : 256)
Query Neighborhood Hits	155	Target Neighborhood Hits	621	Shared Neighborhood Hits	41
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.073300 (rank : 257)
Query Neighborhood Hits	155	Target Neighborhood Hits	573	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

BARD1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.090185 (rank : 233)
Query Neighborhood Hits	155	Target Neighborhood Hits	427	Shared Neighborhood Hits	36
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.088125 (rank : 234)
Query Neighborhood Hits	155	Target Neighborhood Hits	411	Shared Neighborhood Hits	38
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BFAR_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.330138 (rank : 111)
Query Neighborhood Hits	155	Target Neighborhood Hits	222	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.322504 (rank : 116)
Query Neighborhood Hits	155	Target Neighborhood Hits	232	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.066643 (rank : 267)
Query Neighborhood Hits	155	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.061422 (rank : 272)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	32
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.067647 (rank : 265)
Query Neighborhood Hits	155	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.050887 (rank : 288)
Query Neighborhood Hits	155	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC7_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.198022 (rank : 163)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	57
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.079576 (rank : 247)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BRCA1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.313142 (rank : 118)
Query Neighborhood Hits	155	Target Neighborhood Hits	381	Shared Neighborhood Hits	60
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.309481 (rank : 120)
Query Neighborhood Hits	155	Target Neighborhood Hits	436	Shared Neighborhood Hits	60
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CBLB_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.071748 (rank : 261)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	38
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.072860 (rank : 259)
Query Neighborhood Hits	155	Target Neighborhood Hits	277	Shared Neighborhood Hits	38
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.059399 (rank : 274)
Query Neighborhood Hits	155	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.059655 (rank : 273)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	30
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.075653 (rank : 254)
Query Neighborhood Hits	155	Target Neighborhood Hits	353	Shared Neighborhood Hits	40
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.073293 (rank : 258)
Query Neighborhood Hits	155	Target Neighborhood Hits	426	Shared Neighborhood Hits	40
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CHFR_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.179861 (rank : 171)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	49
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.173214 (rank : 174)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	48
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.127353 (rank : 200)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	37
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.145936 (rank : 188)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CNOT4_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.061983 (rank : 271)
Query Neighborhood Hits	155	Target Neighborhood Hits	207	Shared Neighborhood Hits	22
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.058589 (rank : 275)
Query Neighborhood Hits	155	Target Neighborhood Hits	277	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CXAR_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.123725 (rank : 207)
Query Neighborhood Hits	155	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.120835 (rank : 209)
Query Neighborhood Hits	155	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

DTX3L_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.051046 (rank : 286)
Query Neighborhood Hits	155	Target Neighborhood Hits	187	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.175229 (rank : 173)
Query Neighborhood Hits	155	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.178857 (rank : 172)
Query Neighborhood Hits	155	Target Neighborhood Hits	202	Shared Neighborhood Hits	45
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

GPA33_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.076065 (rank : 251)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	45
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.072493 (rank : 260)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

HPLN4_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.050943 (rank : 287)
Query Neighborhood Hits	155	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

ICOSL_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.250259 (rank : 136)
Query Neighborhood Hits	155	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.207383 (rank : 158)
Query Neighborhood Hits	155	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

LNX1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.133539 (rank : 194)
Query Neighborhood Hits	155	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.137115 (rank : 191)
Query Neighborhood Hits	155	Target Neighborhood Hits	377	Shared Neighborhood Hits	55
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.125780 (rank : 204)
Query Neighborhood Hits	155	Target Neighborhood Hits	389	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.126698 (rank : 202)
Query Neighborhood Hits	155	Target Neighborhood Hits	407	Shared Neighborhood Hits	56
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MAT1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.093036 (rank : 227)
Query Neighborhood Hits	155	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.091293 (rank : 231)
Query Neighborhood Hits	155	Target Neighborhood Hits	217	Shared Neighborhood Hits	26
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MEFV_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.523381 (rank : 78)
Query Neighborhood Hits	155	Target Neighborhood Hits	236	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MGRN1_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.050497 (rank : 291)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	25
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.052767 (rank : 282)
Query Neighborhood Hits	155	Target Neighborhood Hits	149	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MKRN2_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.052453 (rank : 284)
Query Neighborhood Hits	155	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.052461 (rank : 283)
Query Neighborhood Hits	155	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MNAB_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.082077 (rank : 241)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.081109 (rank : 242)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

NHLC1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.079997 (rank : 245)
Query Neighborhood Hits	155	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.083942 (rank : 239)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.108849 (rank : 217)
Query Neighborhood Hits	155	Target Neighborhood Hits	222	Shared Neighborhood Hits	37
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.108386 (rank : 218)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.116503 (rank : 213)
Query Neighborhood Hits	155	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.117180 (rank : 212)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.133078 (rank : 196)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.135268 (rank : 193)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	39
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PDL2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.183948 (rank : 167)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PEX10_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.300119 (rank : 121)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	51
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PJA1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.050019 (rank : 292)
Query Neighborhood Hits	155	Target Neighborhood Hits	159	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PML_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.160885 (rank : 182)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	47
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.135828 (rank : 192)
Query Neighborhood Hits	155	Target Neighborhood Hits	246	Shared Neighborhood Hits	48
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PVRL2_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.050615 (rank : 289)
Query Neighborhood Hits	155	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.052160 (rank : 285)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	31
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

PZRN3_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.109431 (rank : 216)
Query Neighborhood Hits	155	Target Neighborhood Hits	461	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.111406 (rank : 214)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	56
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.111354 (rank : 215)
Query Neighborhood Hits	155	Target Neighborhood Hits	438	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.143367 (rank : 189)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.146968 (rank : 187)
Query Neighborhood Hits	155	Target Neighborhood Hits	165	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.158335 (rank : 183)
Query Neighborhood Hits	155	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.181070 (rank : 170)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAG1_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.249660 (rank : 137)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.241664 (rank : 140)
Query Neighborhood Hits	155	Target Neighborhood Hits	189	Shared Neighborhood Hits	52
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RBBP6_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.087041 (rank : 236)
Query Neighborhood Hits	155	Target Neighborhood Hits	1135	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.097175 (rank : 223)
Query Neighborhood Hits	155	Target Neighborhood Hits	1014	Shared Neighborhood Hits	46
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.118358 (rank : 210)
Query Neighborhood Hits	155	Target Neighborhood Hits	433	Shared Neighborhood Hits	53
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.124065 (rank : 205)
Query Neighborhood Hits	155	Target Neighborhood Hits	244	Shared Neighborhood Hits	51
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFFL_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.050515 (rank : 290)
Query Neighborhood Hits	155	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFWD2_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.165581 (rank : 180)
Query Neighborhood Hits	155	Target Neighborhood Hits	518	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.164386 (rank : 181)
Query Neighborhood Hits	155	Target Neighborhood Hits	535	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.231126 (rank : 144)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.226560 (rank : 145)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	51
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.210542 (rank : 153)
Query Neighborhood Hits	155	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.210521 (rank : 154)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RKHD1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.074956 (rank : 255)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN123_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.055367 (rank : 277)
Query Neighborhood Hits	155	Target Neighborhood Hits	175	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.056644 (rank : 276)
Query Neighborhood Hits	155	Target Neighborhood Hits	174	Shared Neighborhood Hits	38
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN125_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.278288 (rank : 130)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	51
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.285617 (rank : 128)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN141_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.172268 (rank : 175)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.170564 (rank : 177)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	48
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.185068 (rank : 166)
Query Neighborhood Hits	155	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.183706 (rank : 168)
Query Neighborhood Hits	155	Target Neighborhood Hits	161	Shared Neighborhood Hits	49
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.080653 (rank : 243)
Query Neighborhood Hits	155	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.083163 (rank : 240)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN166_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.282248 (rank : 129)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.277617 (rank : 131)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	56
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.291826 (rank : 125)
Query Neighborhood Hits	155	Target Neighborhood Hits	370	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.271211 (rank : 132)
Query Neighborhood Hits	155	Target Neighborhood Hits	440	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN169_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.253714 (rank : 135)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.231214 (rank : 143)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.186861 (rank : 165)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.216190 (rank : 148)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.216327 (rank : 147)
Query Neighborhood Hits	155	Target Neighborhood Hits	211	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.075939 (rank : 252)
Query Neighborhood Hits	155	Target Neighborhood Hits	133	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.066857 (rank : 266)
Query Neighborhood Hits	155	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.070470 (rank : 264)
Query Neighborhood Hits	155	Target Neighborhood Hits	153	Shared Neighborhood Hits	26
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.071597 (rank : 262)
Query Neighborhood Hits	155	Target Neighborhood Hits	160	Shared Neighborhood Hits	27
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF41_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.203593 (rank : 160)
Query Neighborhood Hits	155	Target Neighborhood Hits	226	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.203130 (rank : 161)
Query Neighborhood Hits	155	Target Neighborhood Hits	224	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.211566 (rank : 152)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.205054 (rank : 159)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.209637 (rank : 155)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	48
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.208308 (rank : 156)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	48
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF8_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.243068 (rank : 139)
Query Neighborhood Hits	155	Target Neighborhood Hits	622	Shared Neighborhood Hits	60
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.255702 (rank : 134)
Query Neighborhood Hits	155	Target Neighborhood Hits	618	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SMRA3_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.168860 (rank : 178)
Query Neighborhood Hits	155	Target Neighborhood Hits	265	Shared Neighborhood Hits	53
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.156987 (rank : 184)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TIF1A_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.092692 (rank : 228)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	45
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.076596 (rank : 250)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.131704 (rank : 197)
Query Neighborhood Hits	155	Target Neighborhood Hits	312	Shared Neighborhood Hits	50
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.126498 (rank : 203)
Query Neighborhood Hits	155	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.156109 (rank : 185)
Query Neighborhood Hits	155	Target Neighborhood Hits	410	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.152474 (rank : 186)
Query Neighborhood Hits	155	Target Neighborhood Hits	498	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TOPRS_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.092219 (rank : 229)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.094296 (rank : 226)
Query Neighborhood Hits	155	Target Neighborhood Hits	263	Shared Neighborhood Hits	32
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.091432 (rank : 230)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	48
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.095537 (rank : 224)
Query Neighborhood Hits	155	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.065284 (rank : 269)
Query Neighborhood Hits	155	Target Neighborhood Hits	463	Shared Neighborhood Hits	45
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.070921 (rank : 263)
Query Neighborhood Hits	155	Target Neighborhood Hits	476	Shared Neighborhood Hits	44
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.101790 (rank : 222)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.106247 (rank : 221)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	45
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.127115 (rank : 201)
Query Neighborhood Hits	155	Target Neighborhood Hits	355	Shared Neighborhood Hits	48
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF6_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.181233 (rank : 169)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.189149 (rank : 164)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	55
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF7_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.107509 (rank : 219)
Query Neighborhood Hits	155	Target Neighborhood Hits	482	Shared Neighborhood Hits	53
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.107381 (rank : 220)
Query Neighborhood Hits	155	Target Neighborhood Hits	470	Shared Neighborhood Hits	53
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAIP_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.095382 (rank : 225)
Query Neighborhood Hits	155	Target Neighborhood Hits	780	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.079716 (rank : 246)
Query Neighborhood Hits	155	Target Neighborhood Hits	745	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI12_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.593812 (rank : 72)
Query Neighborhood Hits	155	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.482517 (rank : 87)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	63
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.482734 (rank : 86)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI29_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.368483 (rank : 102)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	56
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.367897 (rank : 103)
Query Neighborhood Hits	155	Target Neighborhood Hits	306	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI31_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.595336 (rank : 71)
Query Neighborhood Hits	155	Target Neighborhood Hits	299	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.380905 (rank : 100)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.379397 (rank : 101)
Query Neighborhood Hits	155	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI36_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.297783 (rank : 122)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI37_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.365129 (rank : 104)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.364784 (rank : 105)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI40_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.551028 (rank : 76)
Query Neighborhood Hits	155	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI42_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.207888 (rank : 157)
Query Neighborhood Hits	155	Target Neighborhood Hits	283	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.213746 (rank : 150)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.437792 (rank : 94)
Query Neighborhood Hits	155	Target Neighborhood Hits	393	Shared Neighborhood Hits	62
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.450826 (rank : 92)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.129340 (rank : 198)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.117606 (rank : 211)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI52_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.602091 (rank : 70)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.356631 (rank : 107)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.358043 (rank : 106)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.383642 (rank : 99)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI56_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.236395 (rank : 142)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.236614 (rank : 141)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	58
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI59_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.454252 (rank : 91)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.456154 (rank : 90)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	64
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI63_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.392288 (rank : 98)
Query Neighborhood Hits	155	Target Neighborhood Hits	298	Shared Neighborhood Hits	60
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.399776 (rank : 97)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI73_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.552169 (rank : 75)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	66
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.552835 (rank : 74)
Query Neighborhood Hits	155	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.327249 (rank : 113)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	61
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.327255 (rank : 112)
Query Neighborhood Hits	155	Target Neighborhood Hits	331	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.332376 (rank : 109)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	60
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.337322 (rank : 108)
Query Neighborhood Hits	155	Target Neighborhood Hits	351	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM8_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.437159 (rank : 95)
Query Neighborhood Hits	155	Target Neighborhood Hits	650	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.440227 (rank : 93)
Query Neighborhood Hits	155	Target Neighborhood Hits	674	Shared Neighborhood Hits	68
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UB7I3_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.052770 (rank : 281)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.066170 (rank : 268)
Query Neighborhood Hits	155	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UHRF1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.123754 (rank : 206)
Query Neighborhood Hits	155	Target Neighborhood Hits	272	Shared Neighborhood Hits	49
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.133302 (rank : 195)
Query Neighborhood Hits	155	Target Neighborhood Hits	278	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.170740 (rank : 176)
Query Neighborhood Hits	155	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.167654 (rank : 179)
Query Neighborhood Hits	155	Target Neighborhood Hits	275	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

VSIG2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.079221 (rank : 248)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.075857 (rank : 253)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

ZN179_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.433428 (rank : 96)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN313_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.290035 (rank : 126)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.297623 (rank : 123)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

ERMAP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	155
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
NC score	0.977480 (rank : 2)	θ value	4.72459e-150 (rank : 2)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

BTNL9_HUMAN
NC score	0.951806 (rank : 3)	θ value	4.70527e-49 (rank : 12)
Query Neighborhood Hits	155	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT2A2_HUMAN
NC score	0.949282 (rank : 4)	θ value	7.01481e-53 (rank : 8)
Query Neighborhood Hits	155	Target Neighborhood Hits	191	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A1_HUMAN
NC score	0.940728 (rank : 5)	θ value	1.2411e-41 (rank : 19)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	108
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT3A3_HUMAN
NC score	0.936988 (rank : 6)	θ value	9.78833e-55 (rank : 5)
Query Neighborhood Hits	155	Target Neighborhood Hits	233	Shared Neighborhood Hits	107
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
NC score	0.936441 (rank : 7)	θ value	6.59618e-35 (rank : 26)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	94
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT3A1_HUMAN
NC score	0.935872 (rank : 8)	θ value	1.73182e-43 (rank : 15)
Query Neighborhood Hits	155	Target Neighborhood Hits	229	Shared Neighborhood Hits	108
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT2A3_HUMAN
NC score	0.933659 (rank : 9)	θ value	1.08726e-37 (rank : 23)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	110
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT1A1_MOUSE
NC score	0.931285 (rank : 10)	θ value	5.19021e-56 (rank : 4)
Query Neighborhood Hits	155	Target Neighborhood Hits	252	Shared Neighborhood Hits	116
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_HUMAN
NC score	0.922868 (rank : 11)	θ value	9.48078e-50 (rank : 11)
Query Neighborhood Hits	155	Target Neighborhood Hits	322	Shared Neighborhood Hits	106
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BTNL8_HUMAN
NC score	0.921753 (rank : 12)	θ value	5.0505e-35 (rank : 25)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	102
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

RFPL1_HUMAN
NC score	0.912070 (rank : 13)	θ value	5.97985e-28 (rank : 35)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL3_HUMAN
NC score	0.908442 (rank : 14)	θ value	3.17079e-29 (rank : 32)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL2_HUMAN
NC score	0.905312 (rank : 15)	θ value	5.40856e-29 (rank : 33)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

MEFV_HUMAN
NC score	0.888785 (rank : 16)	θ value	3.974e-56 (rank : 3)
Query Neighborhood Hits	155	Target Neighborhood Hits	431	Shared Neighborhood Hits	80
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI27_MOUSE
NC score	0.872741 (rank : 17)	θ value	3.1488e-53 (rank : 7)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	80
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI27_HUMAN
NC score	0.871421 (rank : 18)	θ value	3.1488e-53 (rank : 6)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	80
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI68_HUMAN
NC score	0.868141 (rank : 19)	θ value	3.72821e-46 (rank : 14)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	80
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI68_MOUSE
NC score	0.861335 (rank : 20)	θ value	1.12253e-42 (rank : 17)
Query Neighborhood Hits	155	Target Neighborhood Hits	356	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI11_MOUSE
NC score	0.859899 (rank : 21)	θ value	7.27602e-42 (rank : 18)
Query Neighborhood Hits	155	Target Neighborhood Hits	329	Shared Neighborhood Hits	81
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI60_MOUSE
NC score	0.857901 (rank : 22)	θ value	1.02001e-27 (rank : 37)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

RNF39_HUMAN
NC score	0.857339 (rank : 23)	θ value	1.02238e-19 (rank : 46)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI11_HUMAN
NC score	0.856509 (rank : 24)	θ value	6.58091e-43 (rank : 16)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	80
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI41_HUMAN
NC score	0.854920 (rank : 25)	θ value	7.80994e-28 (rank : 36)
Query Neighborhood Hits	155	Target Neighborhood Hits	349	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI38_HUMAN
NC score	0.849791 (rank : 26)	θ value	1.42001e-37 (rank : 24)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	80
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM7_HUMAN
NC score	0.848551 (rank : 27)	θ value	1.79631e-32 (rank : 27)
Query Neighborhood Hits	155	Target Neighborhood Hits	336	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

RO52_MOUSE
NC score	0.848297 (rank : 28)	θ value	4.71619e-41 (rank : 20)
Query Neighborhood Hits	155	Target Neighborhood Hits	360	Shared Neighborhood Hits	81
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RO52_HUMAN
NC score	0.844771 (rank : 29)	θ value	6.14528e-49 (rank : 13)
Query Neighborhood Hits	155	Target Neighborhood Hits	419	Shared Neighborhood Hits	80
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRIM7_MOUSE
NC score	0.840483 (rank : 30)	θ value	2.59387e-31 (rank : 30)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	80
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI15_HUMAN
NC score	0.837891 (rank : 31)	θ value	6.61148e-27 (rank : 38)
Query Neighborhood Hits	155	Target Neighborhood Hits	395	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI60_HUMAN
NC score	0.837359 (rank : 32)	θ value	4.89182e-30 (rank : 31)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	80
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI62_MOUSE
NC score	0.836442 (rank : 33)	θ value	4.41421e-39 (rank : 22)
Query Neighborhood Hits	155	Target Neighborhood Hits	478	Shared Neighborhood Hits	80
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI17_HUMAN
NC score	0.835684 (rank : 34)	θ value	1.24688e-25 (rank : 42)
Query Neighborhood Hits	155	Target Neighborhood Hits	318	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI39_MOUSE
NC score	0.830339 (rank : 35)	θ value	1.46268e-50 (rank : 9)
Query Neighborhood Hits	155	Target Neighborhood Hits	691	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
NC score	0.828014 (rank : 36)	θ value	4.25575e-50 (rank : 10)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI14_MOUSE
NC score	0.824242 (rank : 37)	θ value	2.13179e-17 (rank : 50)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI10_MOUSE
NC score	0.824104 (rank : 38)	θ value	7.30988e-26 (rank : 40)
Query Neighborhood Hits	155	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI62_HUMAN
NC score	0.821606 (rank : 39)	θ value	2.58786e-39 (rank : 21)
Query Neighborhood Hits	155	Target Neighborhood Hits	584	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI10_HUMAN
NC score	0.816080 (rank : 40)	θ value	4.73814e-25 (rank : 43)
Query Neighborhood Hits	155	Target Neighborhood Hits	315	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI14_HUMAN
NC score	0.815756 (rank : 41)	θ value	3.28887e-18 (rank : 48)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRIM4_HUMAN
NC score	0.805890 (rank : 42)	θ value	4.74913e-17 (rank : 51)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM6_HUMAN
NC score	0.805721 (rank : 43)	θ value	3.50572e-28 (rank : 34)
Query Neighborhood Hits	155	Target Neighborhood Hits	412	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI17_MOUSE
NC score	0.804462 (rank : 44)	θ value	7.30988e-26 (rank : 41)
Query Neighborhood Hits	155	Target Neighborhood Hits	620	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI49_HUMAN
NC score	0.800042 (rank : 45)	θ value	6.41864e-14 (rank : 60)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRIM6_MOUSE
NC score	0.797025 (rank : 46)	θ value	1.12775e-26 (rank : 39)
Query Neighborhood Hits	155	Target Neighborhood Hits	451	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI50_MOUSE
NC score	0.796289 (rank : 47)	θ value	3.06405e-32 (rank : 28)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	80
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
NC score	0.793694 (rank : 48)	θ value	1.52067e-31 (rank : 29)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	80
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI34_MOUSE
NC score	0.790405 (rank : 49)	θ value	4.91457e-14 (rank : 59)
Query Neighborhood Hits	155	Target Neighborhood Hits	332	Shared Neighborhood Hits	80
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI48_HUMAN
NC score	0.781788 (rank : 50)	θ value	1.86753e-13 (rank : 62)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI43_HUMAN
NC score	0.781049 (rank : 51)	θ value	1.68911e-14 (rank : 57)
Query Neighborhood Hits	155	Target Neighborhood Hits	341	Shared Neighborhood Hits	78
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI34_HUMAN
NC score	0.780027 (rank : 52)	θ value	1.5773e-20 (rank : 45)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

SPRY4_MOUSE
NC score	0.779473 (rank : 53)	θ value	5.08577e-11 (rank : 68)
Query Neighborhood Hits	155	Target Neighborhood Hits	82	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BSPRY_HUMAN
NC score	0.776952 (rank : 54)	θ value	5.26297e-08 (rank : 74)
Query Neighborhood Hits	155	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRIM5_HUMAN
NC score	0.774620 (rank : 55)	θ value	1.058e-16 (rank : 52)
Query Neighborhood Hits	155	Target Neighborhood Hits	424	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI35_HUMAN
NC score	0.771544 (rank : 56)	θ value	2.20605e-14 (rank : 58)
Query Neighborhood Hits	155	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

BSPRY_MOUSE
NC score	0.770671 (rank : 57)	θ value	5.26297e-08 (rank : 75)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI22_HUMAN
NC score	0.764259 (rank : 58)	θ value	5.60996e-18 (rank : 49)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

SPRY4_HUMAN
NC score	0.763020 (rank : 59)	θ value	3.29651e-10 (rank : 70)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI26_HUMAN
NC score	0.757712 (rank : 60)	θ value	7.58209e-15 (rank : 55)
Query Neighborhood Hits	155	Target Neighborhood Hits	335	Shared Neighborhood Hits	78
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI35_MOUSE
NC score	0.757176 (rank : 61)	θ value	1.86753e-13 (rank : 61)
Query Neighborhood Hits	155	Target Neighborhood Hits	465	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI26_MOUSE
NC score	0.751341 (rank : 62)	θ value	6.85773e-16 (rank : 53)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	80
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI30_MOUSE
NC score	0.729366 (rank : 63)	θ value	5.26297e-08 (rank : 76)
Query Neighborhood Hits	155	Target Neighborhood Hits	434	Shared Neighborhood Hits	80
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI16_HUMAN
NC score	0.681163 (rank : 64)	θ value	4.30538e-10 (rank : 71)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	74
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
NC score	0.672030 (rank : 65)	θ value	3.64472e-09 (rank : 73)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	75
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI25_HUMAN
NC score	0.623155 (rank : 66)	θ value	8.67504e-11 (rank : 69)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	80
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI65_MOUSE
NC score	0.613508 (rank : 67)	θ value	4.1701e-05 (rank : 79)
Query Neighborhood Hits	155	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI25_MOUSE
NC score	0.608635 (rank : 68)	θ value	7.84624e-12 (rank : 67)
Query Neighborhood Hits	155	Target Neighborhood Hits	446	Shared Neighborhood Hits	80
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI65_HUMAN
NC score	0.606947 (rank : 69)	θ value	0.00390308 (rank : 81)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI52_HUMAN
NC score	0.602091 (rank : 70)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI31_HUMAN
NC score	0.595336 (rank : 71)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	155	Target Neighborhood Hits	299	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI12_MOUSE
NC score	0.593812 (rank : 72)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	155	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI18_HUMAN
NC score	0.569135 (rank : 73)	θ value	1.29331e-14 (rank : 56)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI74_HUMAN
NC score	0.552835 (rank : 74)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	155	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI73_HUMAN
NC score	0.552169 (rank : 75)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	66
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI40_HUMAN
NC score	0.551028 (rank : 76)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	155	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI18_MOUSE
NC score	0.543274 (rank : 77)	θ value	1.58096e-12 (rank : 64)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	82
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

MEFV_MOUSE
NC score	0.523381 (rank : 78)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	155	Target Neighborhood Hits	236	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRIM1_HUMAN
NC score	0.511316 (rank : 79)	θ value	3.52202e-12 (rank : 66)
Query Neighborhood Hits	155	Target Neighborhood Hits	345	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.510772 (rank : 80)	θ value	2.69671e-12 (rank : 65)
Query Neighborhood Hits	155	Target Neighborhood Hits	361	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI47_MOUSE
NC score	0.500852 (rank : 81)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	155	Target Neighborhood Hits	295	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

BTNL1_MOUSE
NC score	0.495144 (rank : 82)	θ value	4.44505e-15 (rank : 54)
Query Neighborhood Hits	155	Target Neighborhood Hits	151	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

MOG_MOUSE
NC score	0.495116 (rank : 83)	θ value	6.40375e-22 (rank : 44)
Query Neighborhood Hits	155	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_HUMAN
NC score	0.494914 (rank : 84)	θ value	2.5182e-18 (rank : 47)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	32
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

BT3A2_HUMAN
NC score	0.488052 (rank : 85)	θ value	1.25267e-09 (rank : 72)
Query Neighborhood Hits	155	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

TRI13_MOUSE
NC score	0.482734 (rank : 86)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.482517 (rank : 87)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	63
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI47_HUMAN
NC score	0.480857 (rank : 88)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	80
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

BTNL2_HUMAN
NC score	0.478002 (rank : 89)	θ value	2.43908e-13 (rank : 63)
Query Neighborhood Hits	155	Target Neighborhood Hits	164	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

TRI59_MOUSE
NC score	0.456154 (rank : 90)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	64
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.454252 (rank : 91)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI44_MOUSE
NC score	0.450826 (rank : 92)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRIM8_MOUSE
NC score	0.440227 (rank : 93)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	155	Target Neighborhood Hits	674	Shared Neighborhood Hits	68
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI44_HUMAN
NC score	0.437792 (rank : 94)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	155	Target Neighborhood Hits	393	Shared Neighborhood Hits	62
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRIM8_HUMAN
NC score	0.437159 (rank : 95)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	155	Target Neighborhood Hits	650	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN179_HUMAN
NC score	0.433428 (rank : 96)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI63_MOUSE
NC score	0.399776 (rank : 97)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI63_HUMAN
NC score	0.392288 (rank : 98)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	155	Target Neighborhood Hits	298	Shared Neighborhood Hits	60
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI55_HUMAN
NC score	0.383642 (rank : 99)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI32_HUMAN
NC score	0.380905 (rank : 100)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.379397 (rank : 101)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	155	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI29_HUMAN
NC score	0.368483 (rank : 102)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	56
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
NC score	0.367897 (rank : 103)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	155	Target Neighborhood Hits	306	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI37_HUMAN
NC score	0.365129 (rank : 104)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.364784 (rank : 105)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI54_MOUSE
NC score	0.358043 (rank : 106)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_HUMAN
NC score	0.356631 (rank : 107)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM3_MOUSE
NC score	0.337322 (rank : 108)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	155	Target Neighborhood Hits	351	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.332376 (rank : 109)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	60
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM9_HUMAN
NC score	0.331115 (rank : 110)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

BFAR_HUMAN
NC score	0.330138 (rank : 111)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	155	Target Neighborhood Hits	222	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRIM2_MOUSE
NC score	0.327255 (rank : 112)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	155	Target Neighborhood Hits	331	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM2_HUMAN
NC score	0.327249 (rank : 113)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	61
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI46_MOUSE
NC score	0.324448 (rank : 114)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	155	Target Neighborhood Hits	287	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.324057 (rank : 115)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	155	Target Neighborhood Hits	291	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

BFAR_MOUSE
NC score	0.322504 (rank : 116)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	155	Target Neighborhood Hits	232	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRIM9_MOUSE
NC score	0.317051 (rank : 117)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

BRCA1_HUMAN
NC score	0.313142 (rank : 118)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	155	Target Neighborhood Hits	381	Shared Neighborhood Hits	60
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CD276_MOUSE
NC score	0.310621 (rank : 119)	θ value	3.77169e-06 (rank : 78)
Query Neighborhood Hits	155	Target Neighborhood Hits	243	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

BRCA1_MOUSE
NC score	0.309481 (rank : 120)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	155	Target Neighborhood Hits	436	Shared Neighborhood Hits	60
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

PEX10_HUMAN
NC score	0.300119 (rank : 121)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	51
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRI36_HUMAN
NC score	0.297783 (rank : 122)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

ZN313_MOUSE
NC score	0.297623 (rank : 123)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI36_MOUSE
NC score	0.292604 (rank : 124)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	155	Target Neighborhood Hits	266	Shared Neighborhood Hits	79
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

RN168_HUMAN
NC score	0.291826 (rank : 125)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	155	Target Neighborhood Hits	370	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN313_HUMAN
NC score	0.290035 (rank : 126)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

CD276_HUMAN
NC score	0.287800 (rank : 127)	θ value	1.69304e-06 (rank : 77)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

RN125_MOUSE
NC score	0.285617 (rank : 128)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
NC score	0.282248 (rank : 129)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN125_HUMAN
NC score	0.278288 (rank : 130)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	51
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN166_MOUSE
NC score	0.277617 (rank : 131)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	56
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_MOUSE
NC score	0.271211 (rank : 132)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	155	Target Neighborhood Hits	440	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

PDL1_MOUSE
NC score	0.259043 (rank : 133)	θ value	0.00228821 (rank : 80)
Query Neighborhood Hits	155	Target Neighborhood Hits	168	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

RNF8_MOUSE
NC score	0.255702 (rank : 134)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	155	Target Neighborhood Hits	618	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RN169_HUMAN
NC score	0.253714 (rank : 135)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

ICOSL_HUMAN
NC score	0.250259 (rank : 136)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	155	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

RAG1_HUMAN
NC score	0.249660 (rank : 137)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

HHLA2_HUMAN
NC score	0.246707 (rank : 138)	θ value	0.0961366 (rank : 90)
Query Neighborhood Hits	155	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

RNF8_HUMAN
NC score	0.243068 (rank : 139)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	155	Target Neighborhood Hits	622	Shared Neighborhood Hits	60
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RAG1_MOUSE
NC score	0.241664 (rank : 140)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	155	Target Neighborhood Hits	189	Shared Neighborhood Hits	52
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI56_MOUSE
NC score	0.236614 (rank : 141)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	58
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.236395 (rank : 142)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

RN183_HUMAN
NC score	0.231214 (rank : 143)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RING1_HUMAN
NC score	0.231126 (rank : 144)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.226560 (rank : 145)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	51
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

CD86_HUMAN
NC score	0.221316 (rank : 146)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

RN185_MOUSE
NC score	0.216327 (rank : 147)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	155	Target Neighborhood Hits	211	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_HUMAN
NC score	0.216190 (rank : 148)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

PDL1_HUMAN
NC score	0.215534 (rank : 149)	θ value	0.0148317 (rank : 83)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

TRI42_MOUSE
NC score	0.213746 (rank : 150)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

CD86_MOUSE
NC score	0.211967 (rank : 151)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

RNF4_HUMAN
NC score	0.211566 (rank : 152)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RING2_HUMAN
NC score	0.210542 (rank : 153)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	155	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.210521 (rank : 154)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RNF5_HUMAN
NC score	0.209637 (rank : 155)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	48
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.208308 (rank : 156)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	48
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI42_HUMAN
NC score	0.207888 (rank : 157)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	155	Target Neighborhood Hits	283	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ICOSL_MOUSE
NC score	0.207383 (rank : 158)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	155	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

RNF4_MOUSE
NC score	0.205054 (rank : 159)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF41_HUMAN
NC score	0.203593 (rank : 160)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	155	Target Neighborhood Hits	226	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.203130 (rank : 161)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	155	Target Neighborhood Hits	224	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

PDL2_HUMAN
NC score	0.198069 (rank : 162)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	155	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

BIRC7_HUMAN
NC score	0.198022 (rank : 163)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	57
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

TRAF6_MOUSE
NC score	0.189149 (rank : 164)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	55
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

RN183_MOUSE
NC score	0.186861 (rank : 165)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN146_HUMAN
NC score	0.185068 (rank : 166)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	155	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

PDL2_MOUSE
NC score	0.183948 (rank : 167)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

RN146_MOUSE
NC score	0.183706 (rank : 168)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	155	Target Neighborhood Hits	161	Shared Neighborhood Hits	49
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRAF6_HUMAN
NC score	0.181233 (rank : 169)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RAD18_MOUSE
NC score	0.181070 (rank : 170)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

CHFR_HUMAN
NC score	0.179861 (rank : 171)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	49
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

DTX3_MOUSE
NC score	0.178857 (rank : 172)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	155	Target Neighborhood Hits	202	Shared Neighborhood Hits	45
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DTX3_HUMAN
NC score	0.175229 (rank : 173)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	155	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

CHFR_MOUSE
NC score	0.173214 (rank : 174)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	48
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN141_HUMAN
NC score	0.172268 (rank : 175)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

UHRF2_HUMAN
NC score	0.170740 (rank : 176)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	155	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RN141_MOUSE
NC score	0.170564 (rank : 177)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	48
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

SMRA3_HUMAN
NC score	0.168860 (rank : 178)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	155	Target Neighborhood Hits	265	Shared Neighborhood Hits	53
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

UHRF2_MOUSE
NC score	0.167654 (rank : 179)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	155	Target Neighborhood Hits	275	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

RFWD2_HUMAN
NC score	0.165581 (rank : 180)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	155	Target Neighborhood Hits	518	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.164386 (rank : 181)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	155	Target Neighborhood Hits	535	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

PML_HUMAN
NC score	0.160885 (rank : 182)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	47
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RAD18_HUMAN
NC score	0.158335 (rank : 183)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	155	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

SMRA3_MOUSE
NC score	0.156987 (rank : 184)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TIF1G_HUMAN
NC score	0.156109 (rank : 185)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	155	Target Neighborhood Hits	410	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.152474 (rank : 186)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	155	Target Neighborhood Hits	498	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

R113B_HUMAN
NC score	0.146968 (rank : 187)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	155	Target Neighborhood Hits	165	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

CM007_MOUSE
NC score	0.145936 (rank : 188)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

R113A_HUMAN
NC score	0.143367 (rank : 189)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

CD80_MOUSE
NC score	0.138907 (rank : 190)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

LNX1_MOUSE
NC score	0.137115 (rank : 191)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	155	Target Neighborhood Hits	377	Shared Neighborhood Hits	55
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PML_MOUSE
NC score	0.135828 (rank : 192)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	155	Target Neighborhood Hits	246	Shared Neighborhood Hits	48
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PCGF6_MOUSE
NC score	0.135268 (rank : 193)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	39
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

LNX1_HUMAN
NC score	0.133539 (rank : 194)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	155	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

UHRF1_MOUSE
NC score	0.133302 (rank : 195)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	155	Target Neighborhood Hits	278	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PCGF6_HUMAN
NC score	0.133078 (rank : 196)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TIF1B_HUMAN
NC score	0.131704 (rank : 197)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	155	Target Neighborhood Hits	312	Shared Neighborhood Hits	50
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI45_HUMAN
NC score	0.129340 (rank : 198)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

CD80_HUMAN
NC score	0.128065 (rank : 199)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	155	Target Neighborhood Hits	129	Shared Neighborhood Hits	31
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

CM007_HUMAN
NC score	0.127353 (rank : 200)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	37
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRAF5_MOUSE
NC score	0.127115 (rank : 201)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	155	Target Neighborhood Hits	355	Shared Neighborhood Hits	48
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

LNX2_MOUSE
NC score	0.126698 (rank : 202)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	155	Target Neighborhood Hits	407	Shared Neighborhood Hits	56
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TIF1B_MOUSE
NC score	0.126498 (rank : 203)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	155	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

LNX2_HUMAN
NC score	0.125780 (rank : 204)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	155	Target Neighborhood Hits	389	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RC3H1_MOUSE
NC score	0.124065 (rank : 205)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	155	Target Neighborhood Hits	244	Shared Neighborhood Hits	51
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

UHRF1_HUMAN
NC score	0.123754 (rank : 206)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	155	Target Neighborhood Hits	272	Shared Neighborhood Hits	49
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CXAR_HUMAN
NC score	0.123725 (rank : 207)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	155	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

TPSNR_MOUSE
NC score	0.121539 (rank : 208)	θ value	0.0736092 (rank : 88)
Query Neighborhood Hits	155	Target Neighborhood Hits	336	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

CXAR_MOUSE
NC score	0.120835 (rank : 209)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	155	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

RC3H1_HUMAN
NC score	0.118358 (rank : 210)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	155	Target Neighborhood Hits	433	Shared Neighborhood Hits	53
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TRI45_MOUSE
NC score	0.117606 (rank : 211)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

PCGF4_MOUSE
NC score	0.117180 (rank : 212)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.116503 (rank : 213)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	155	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PZRN3_MOUSE
NC score	0.111406 (rank : 214)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	56
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
NC score	0.111354 (rank : 215)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	155	Target Neighborhood Hits	438	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_HUMAN
NC score	0.109431 (rank : 216)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	155	Target Neighborhood Hits	461	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PCGF2_HUMAN
NC score	0.108849 (rank : 217)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	155	Target Neighborhood Hits	222	Shared Neighborhood Hits	37
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.108386 (rank : 218)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRAF7_HUMAN
NC score	0.107509 (rank : 219)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	155	Target Neighborhood Hits	482	Shared Neighborhood Hits	53
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
NC score	0.107381 (rank : 220)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	155	Target Neighborhood Hits	470	Shared Neighborhood Hits	53
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF5_HUMAN
NC score	0.106247 (rank : 221)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	45
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF4_HUMAN
NC score	0.101790 (rank : 222)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RBBP6_MOUSE
NC score	0.097175 (rank : 223)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	155	Target Neighborhood Hits	1014	Shared Neighborhood Hits	46
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRAF2_MOUSE
NC score	0.095537 (rank : 224)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	155	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAIP_HUMAN
NC score	0.095382 (rank : 225)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	155	Target Neighborhood Hits	780	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TOPRS_MOUSE
NC score	0.094296 (rank : 226)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	155	Target Neighborhood Hits	263	Shared Neighborhood Hits	32
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

MAT1_HUMAN
NC score	0.093036 (rank : 227)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	155	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

TIF1A_HUMAN
NC score	0.092692 (rank : 228)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	45
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TOPRS_HUMAN
NC score	0.092219 (rank : 229)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
NC score	0.091432 (rank : 230)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	48
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

MAT1_MOUSE
NC score	0.091293 (rank : 231)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	155	Target Neighborhood Hits	217	Shared Neighborhood Hits	26
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

TIMD3_HUMAN
NC score	0.090214 (rank : 232)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	155	Target Neighborhood Hits	62	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDQ0, Q8WW60, Q96K94	Gene names	HAVCR2, TIM3, TIMD3
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 2 precursor (HAVcr-2) (T cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T cell membrane protein 3) (TIM-3).

BARD1_HUMAN
NC score	0.090185 (rank : 233)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	155	Target Neighborhood Hits	427	Shared Neighborhood Hits	36
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
NC score	0.088125 (rank : 234)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	155	Target Neighborhood Hits	411	Shared Neighborhood Hits	38
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

JAML1_MOUSE
NC score	0.087202 (rank : 235)	θ value	0.0330416 (rank : 86)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	32
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

RBBP6_HUMAN
NC score	0.087041 (rank : 236)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	155	Target Neighborhood Hits	1135	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

AMFR_MOUSE
NC score	0.084919 (rank : 237)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	155	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.084510 (rank : 238)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

NHLC1_MOUSE
NC score	0.083942 (rank : 239)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN152_MOUSE
NC score	0.083163 (rank : 240)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

MNAB_HUMAN
NC score	0.082077 (rank : 241)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
NC score	0.081109 (rank : 242)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RN152_HUMAN
NC score	0.080653 (rank : 243)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	155	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TIMD3_MOUSE
NC score	0.080302 (rank : 244)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	155	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VIM0	Gene names	Havcr2, Tim3, Timd3
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 2 homolog precursor (HAVcr-2) (T cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T cell membrane protein 3) (TIM-3).

NHLC1_HUMAN
NC score	0.079997 (rank : 245)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	155	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAIP_MOUSE
NC score	0.079716 (rank : 246)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	155	Target Neighborhood Hits	745	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

BIRC8_HUMAN
NC score	0.079576 (rank : 247)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

VSIG2_HUMAN
NC score	0.079221 (rank : 248)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

TPSNR_HUMAN
NC score	0.079121 (rank : 249)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BX59, Q9NWB8	Gene names	TAPBPL
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

TIF1A_MOUSE
NC score	0.076596 (rank : 250)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

GPA33_HUMAN
NC score	0.076065 (rank : 251)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	45
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

RNF32_HUMAN
NC score	0.075939 (rank : 252)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	155	Target Neighborhood Hits	133	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

VSIG2_MOUSE
NC score	0.075857 (rank : 253)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

CBL_HUMAN
NC score	0.075653 (rank : 254)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	155	Target Neighborhood Hits	353	Shared Neighborhood Hits	40
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

RKHD1_HUMAN
NC score	0.074956 (rank : 255)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

ARD1_HUMAN
NC score	0.073606 (rank : 256)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	155	Target Neighborhood Hits	621	Shared Neighborhood Hits	41
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
NC score	0.073300 (rank : 257)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	155	Target Neighborhood Hits	573	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

CBL_MOUSE
NC score	0.073293 (rank : 258)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	155	Target Neighborhood Hits	426	Shared Neighborhood Hits	40
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLB_MOUSE
NC score	0.072860 (rank : 259)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	155	Target Neighborhood Hits	277	Shared Neighborhood Hits	38
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

GPA33_MOUSE
NC score	0.072493 (rank : 260)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

CBLB_HUMAN
NC score	0.071748 (rank : 261)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	38
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

RNF34_MOUSE
NC score	0.071597 (rank : 262)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	155	Target Neighborhood Hits	160	Shared Neighborhood Hits	27
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRAF3_MOUSE
NC score	0.070921 (rank : 263)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	155	Target Neighborhood Hits	476	Shared Neighborhood Hits	44
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RNF34_HUMAN
NC score	0.070470 (rank : 264)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	155	Target Neighborhood Hits	153	Shared Neighborhood Hits	26
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

BIRC3_HUMAN
NC score	0.067647 (rank : 265)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	155	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

RNF32_MOUSE
NC score	0.066857 (rank : 266)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	155	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

BIRC2_HUMAN
NC score	0.066643 (rank : 267)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	155	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

UB7I3_MOUSE
NC score	0.066170 (rank : 268)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	155	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

TRAF3_HUMAN
NC score	0.065284 (rank : 269)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	155	Target Neighborhood Hits	463	Shared Neighborhood Hits	45
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

HPLN3_MOUSE
NC score	0.063723 (rank : 270)	θ value	0.0330416 (rank : 84)
Query Neighborhood Hits	155	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

CNOT4_HUMAN
NC score	0.061983 (rank : 271)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	155	Target Neighborhood Hits	207	Shared Neighborhood Hits	22
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BIRC2_MOUSE
NC score	0.061422 (rank : 272)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	32
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

CBLC_MOUSE
NC score	0.059655 (rank : 273)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	30
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBLC_HUMAN
NC score	0.059399 (rank : 274)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	155	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CNOT4_MOUSE
NC score	0.058589 (rank : 275)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	155	Target Neighborhood Hits	277	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RN123_MOUSE
NC score	0.056644 (rank : 276)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	155	Target Neighborhood Hits	174	Shared Neighborhood Hits	38
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_HUMAN
NC score	0.055367 (rank : 277)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	155	Target Neighborhood Hits	175	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

JAML1_HUMAN
NC score	0.055315 (rank : 278)	θ value	0.0330416 (rank : 85)
Query Neighborhood Hits	155	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

PIGR_MOUSE
NC score	0.054058 (rank : 279)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	155	Target Neighborhood Hits	214	Shared Neighborhood Hits	32
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

VSIG4_HUMAN
NC score	0.053905 (rank : 280)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	155	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

UB7I3_HUMAN
NC score	0.052770 (rank : 281)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

MGRN1_MOUSE
NC score	0.052767 (rank : 282)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	155	Target Neighborhood Hits	149	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MKRN2_MOUSE
NC score	0.052461 (rank : 283)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	155	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN2_HUMAN
NC score	0.052453 (rank : 284)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	155	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

PVR_HUMAN
NC score	0.052160 (rank : 285)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	31
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

DTX3L_HUMAN
NC score	0.051046 (rank : 286)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	155	Target Neighborhood Hits	187	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

HPLN4_MOUSE
NC score	0.050943 (rank : 287)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	155	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

BIRC3_MOUSE
NC score	0.050887 (rank : 288)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	155	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

PVRL2_MOUSE
NC score	0.050615 (rank : 289)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	155	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

RFFL_HUMAN
NC score	0.050515 (rank : 290)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	155	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MGRN1_HUMAN
NC score	0.050497 (rank : 291)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	25
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

PJA1_HUMAN
NC score	0.050019 (rank : 292)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	155	Target Neighborhood Hits	159	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

HPLN2_MOUSE
NC score	0.045927 (rank : 293)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	155	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

PIGR_HUMAN
NC score	0.045857 (rank : 294)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	155	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

HPLN3_HUMAN
NC score	0.044509 (rank : 295)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	155	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN1_MOUSE
NC score	0.039111 (rank : 296)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	155	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

SIGL5_HUMAN
NC score	0.037852 (rank : 297)	θ value	0.0113563 (rank : 82)
Query Neighborhood Hits	155	Target Neighborhood Hits	246	Shared Neighborhood Hits	36
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

HPLN1_HUMAN
NC score	0.035626 (rank : 298)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	155	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
NC score	0.035163 (rank : 299)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	155	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

CSPG2_HUMAN
NC score	0.034570 (rank : 300)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	155	Target Neighborhood Hits	681	Shared Neighborhood Hits	30
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TREM1_MOUSE
NC score	0.033144 (rank : 301)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JKE2, Q3TAL7	Gene names	Trem1
Domain Architecture	No domain graphic available
Description	Triggering receptor expressed on myeloid cells 1 precursor (TREM-1).

CD47_MOUSE
NC score	0.029365 (rank : 302)	θ value	0.125558 (rank : 91)
Query Neighborhood Hits	155	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q61735, Q921Z2	Gene names	Cd47
Domain Architecture	No domain graphic available
Description	Leukocyte surface antigen CD47 precursor (Integrin-associated protein) (IAP).

HV34_MOUSE
NC score	0.028410 (rank : 303)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	26
SwissProt Accessions	P01803	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region AMPC1.

HV28_MOUSE
NC score	0.028362 (rank : 304)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	P01797	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region U61.

HV27_MOUSE
NC score	0.028190 (rank : 305)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	155	Target Neighborhood Hits	202	Shared Neighborhood Hits	26
SwissProt Accessions	P01796	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region A4.

HV32_MOUSE
NC score	0.028093 (rank : 306)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	155	Target Neighborhood Hits	204	Shared Neighborhood Hits	26
SwissProt Accessions	P01801	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region J606.

HV29_MOUSE
NC score	0.024724 (rank : 307)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	P01798	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region E109.

HV33_MOUSE
NC score	0.023586 (rank : 308)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	P01802	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region W3082.

HV30_MOUSE
NC score	0.023088 (rank : 309)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	155	Target Neighborhood Hits	216	Shared Neighborhood Hits	25
SwissProt Accessions	P01799	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region ABE-47N.

HV31_MOUSE
NC score	0.022816 (rank : 310)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	155	Target Neighborhood Hits	176	Shared Neighborhood Hits	24
SwissProt Accessions	P01800	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region T957.

CSPG2_MOUSE
NC score	0.021612 (rank : 311)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	155	Target Neighborhood Hits	711	Shared Neighborhood Hits	23
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PVRL2_HUMAN
NC score	0.021554 (rank : 312)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	23
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

HV3T_HUMAN
NC score	0.021320 (rank : 313)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	P01781	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region GAL.

HV19_MOUSE
NC score	0.021250 (rank : 314)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	155	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	P01788	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region H8.

HV18_MOUSE
NC score	0.021046 (rank : 315)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	155	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	P01787	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V regions TEPC 15/S107/HPCM1/HPCM2/HPCM3.

HV22_MOUSE
NC score	0.021039 (rank : 316)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	155	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	P01791	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region HPCM6.

SIGL8_HUMAN
NC score	0.021023 (rank : 317)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	155	Target Neighborhood Hits	252	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

HV21_MOUSE
NC score	0.020834 (rank : 318)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	155	Target Neighborhood Hits	229	Shared Neighborhood Hits	22
SwissProt Accessions	P01790	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region M511.

CD33_HUMAN
NC score	0.020709 (rank : 319)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	155	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	P20138, Q8TD24	Gene names	CD33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3) (gp67).

VCAM1_HUMAN
NC score	0.020525 (rank : 320)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	155	Target Neighborhood Hits	352	Shared Neighborhood Hits	32
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

HV20_MOUSE
NC score	0.020410 (rank : 321)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	22
SwissProt Accessions	P01789	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region M603.

CEAM6_HUMAN
NC score	0.020323 (rank : 322)	θ value	0.0961366 (rank : 89)
Query Neighborhood Hits	155	Target Neighborhood Hits	308	Shared Neighborhood Hits	32
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

HV25_MOUSE
NC score	0.020040 (rank : 323)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	155	Target Neighborhood Hits	216	Shared Neighborhood Hits	22
SwissProt Accessions	P01794	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region HPCG14.

SIGL6_HUMAN
NC score	0.019908 (rank : 324)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	155	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

HV23_MOUSE
NC score	0.019572 (rank : 325)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	155	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	P01792	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region HPCG8.

HV3K_HUMAN
NC score	0.019464 (rank : 326)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	25
SwissProt Accessions	P01772	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region KOL.

HV17_MOUSE
NC score	0.019221 (rank : 327)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	155	Target Neighborhood Hits	238	Shared Neighborhood Hits	21
SwissProt Accessions	P01786	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region MOPC 47A.

HV26_MOUSE
NC score	0.017924 (rank : 328)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	155	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P01795	Gene names
Domain Architecture
Description	Ig heavy chain V region M167 precursor.

SLAF5_MOUSE
NC score	0.017021 (rank : 329)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	155	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	Q18PI6, Q18PI7, Q3TBT1, Q3U0A2, Q8BFV0, Q9Z178	Gene names	Cd84, Slamf5
Domain Architecture	No domain graphic available
Description	SLAM family member 5 precursor (Signaling lymphocytic activation molecule 5) (Leukocyte differentiation antigen CD84) (CD84 antigen).

SIGL7_HUMAN
NC score	0.016232 (rank : 330)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	155	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

DCC_HUMAN
NC score	0.014876 (rank : 331)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	155	Target Neighborhood Hits	583	Shared Neighborhood Hits	41
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

TITIN_HUMAN
NC score	0.014186 (rank : 332)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	155	Target Neighborhood Hits	2923	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NEO1_MOUSE
NC score	0.014104 (rank : 333)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	155	Target Neighborhood Hits	523	Shared Neighborhood Hits	33
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

IRPL1_MOUSE
NC score	0.012859 (rank : 334)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

KIRR2_MOUSE
NC score	0.012329 (rank : 335)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

CEAM1_HUMAN
NC score	0.012126 (rank : 336)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	155	Target Neighborhood Hits	348	Shared Neighborhood Hits	31
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

KIRR2_HUMAN
NC score	0.011907 (rank : 337)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

CDON_HUMAN
NC score	0.011138 (rank : 338)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	155	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

LY9_HUMAN
NC score	0.008675 (rank : 339)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	155	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBG7, Q14775, Q5VYI3, Q9H4N5, Q9NQ24	Gene names	LY9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9) (CD229 antigen).

ICAM5_MOUSE
NC score	0.008080 (rank : 340)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	155	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

DZIP1_MOUSE
NC score	0.007236 (rank : 341)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	155	Target Neighborhood Hits	530	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

ILRL1_MOUSE
NC score	0.006745 (rank : 342)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	155	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

UTRO_HUMAN
NC score	-0.002077 (rank : 343)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	155	Target Neighborhood Hits	960	Shared Neighborhood Hits	5
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).