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Network neighborhood for query Sequence : TRIM6_MOUSE

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TRIM6_MOUSE
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRIM6_HUMAN
θ value	0 (rank : 1)	NC score	0.985529 (rank : 2)
Query Neighborhood Hits	451	Target Neighborhood Hits	412	Shared Neighborhood Hits	309
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	451	Target Neighborhood Hits	451	Shared Neighborhood Hits	451
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI34_HUMAN
θ value	2.2711e-144 (rank : 3)	NC score	0.971725 (rank : 5)
Query Neighborhood Hits	451	Target Neighborhood Hits	416	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI22_HUMAN
θ value	8.0776e-142 (rank : 4)	NC score	0.975532 (rank : 4)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRIM5_HUMAN
θ value	2.87295e-139 (rank : 5)	NC score	0.978219 (rank : 3)
Query Neighborhood Hits	451	Target Neighborhood Hits	424	Shared Neighborhood Hits	282
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI34_MOUSE
θ value	1.25199e-126 (rank : 6)	NC score	0.967882 (rank : 6)
Query Neighborhood Hits	451	Target Neighborhood Hits	332	Shared Neighborhood Hits	230
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI30_MOUSE
θ value	1.13764e-111 (rank : 7)	NC score	0.966322 (rank : 7)
Query Neighborhood Hits	451	Target Neighborhood Hits	434	Shared Neighborhood Hits	292
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

RO52_HUMAN
θ value	1.18001e-100 (rank : 8)	NC score	0.964325 (rank : 9)
Query Neighborhood Hits	451	Target Neighborhood Hits	419	Shared Neighborhood Hits	285
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI68_HUMAN
θ value	3.44127e-92 (rank : 9)	NC score	0.962184 (rank : 10)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	226
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RO52_MOUSE
θ value	4.20666e-90 (rank : 10)	NC score	0.965508 (rank : 8)
Query Neighborhood Hits	451	Target Neighborhood Hits	360	Shared Neighborhood Hits	261
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI68_MOUSE
θ value	1.2666e-86 (rank : 11)	NC score	0.959389 (rank : 12)
Query Neighborhood Hits	451	Target Neighborhood Hits	356	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI38_HUMAN
θ value	3.34088e-79 (rank : 12)	NC score	0.959940 (rank : 11)
Query Neighborhood Hits	451	Target Neighborhood Hits	373	Shared Neighborhood Hits	266
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI11_HUMAN
θ value	1.07722e-69 (rank : 13)	NC score	0.949528 (rank : 15)
Query Neighborhood Hits	451	Target Neighborhood Hits	316	Shared Neighborhood Hits	240
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI27_HUMAN
θ value	2.65329e-68 (rank : 14)	NC score	0.947478 (rank : 18)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI39_MOUSE
θ value	5.91091e-68 (rank : 15)	NC score	0.936717 (rank : 26)
Query Neighborhood Hits	451	Target Neighborhood Hits	691	Shared Neighborhood Hits	340
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI27_MOUSE
θ value	7.71989e-68 (rank : 16)	NC score	0.946006 (rank : 19)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	205
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI17_MOUSE
θ value	3.58603e-65 (rank : 17)	NC score	0.935628 (rank : 27)
Query Neighborhood Hits	451	Target Neighborhood Hits	620	Shared Neighborhood Hits	322
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI11_MOUSE
θ value	6.11685e-65 (rank : 18)	NC score	0.951185 (rank : 14)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	246
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI39_HUMAN
θ value	7.98882e-65 (rank : 19)	NC score	0.935265 (rank : 28)
Query Neighborhood Hits	451	Target Neighborhood Hits	693	Shared Neighborhood Hits	342
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI60_HUMAN
θ value	2.10721e-57 (rank : 20)	NC score	0.951680 (rank : 13)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	267
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI12_MOUSE
θ value	2.32979e-56 (rank : 21)	NC score	0.910442 (rank : 37)
Query Neighborhood Hits	451	Target Neighborhood Hits	387	Shared Neighborhood Hits	255
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM7_MOUSE
θ value	1.32293e-51 (rank : 22)	NC score	0.942170 (rank : 21)
Query Neighborhood Hits	451	Target Neighborhood Hits	358	Shared Neighborhood Hits	262
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

MEFV_HUMAN
θ value	2.49495e-50 (rank : 23)	NC score	0.883742 (rank : 43)
Query Neighborhood Hits	451	Target Neighborhood Hits	431	Shared Neighborhood Hits	172
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI17_HUMAN
θ value	4.25575e-50 (rank : 24)	NC score	0.948482 (rank : 17)
Query Neighborhood Hits	451	Target Neighborhood Hits	318	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM7_HUMAN
θ value	2.75849e-49 (rank : 25)	NC score	0.941844 (rank : 22)
Query Neighborhood Hits	451	Target Neighborhood Hits	336	Shared Neighborhood Hits	257
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI49_HUMAN
θ value	5.20228e-48 (rank : 26)	NC score	0.929494 (rank : 30)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRIM4_HUMAN
θ value	1.51363e-47 (rank : 27)	NC score	0.949108 (rank : 16)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	250
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI43_HUMAN
θ value	4.86918e-46 (rank : 28)	NC score	0.944554 (rank : 20)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	258
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI60_MOUSE
θ value	1.41672e-45 (rank : 29)	NC score	0.940340 (rank : 24)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	197
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI41_HUMAN
θ value	2.41655e-45 (rank : 30)	NC score	0.930859 (rank : 29)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	241
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI10_HUMAN
θ value	2.04573e-44 (rank : 31)	NC score	0.941061 (rank : 23)
Query Neighborhood Hits	451	Target Neighborhood Hits	315	Shared Neighborhood Hits	246
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI26_HUMAN
θ value	2.04573e-44 (rank : 32)	NC score	0.926871 (rank : 31)
Query Neighborhood Hits	451	Target Neighborhood Hits	335	Shared Neighborhood Hits	242
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI10_MOUSE
θ value	2.95404e-43 (rank : 33)	NC score	0.936742 (rank : 25)
Query Neighborhood Hits	451	Target Neighborhood Hits	285	Shared Neighborhood Hits	229
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI26_MOUSE
θ value	1.62093e-41 (rank : 34)	NC score	0.924366 (rank : 32)
Query Neighborhood Hits	451	Target Neighborhood Hits	339	Shared Neighborhood Hits	249
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI50_HUMAN
θ value	3.61106e-41 (rank : 35)	NC score	0.913267 (rank : 36)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	231
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_MOUSE
θ value	3.99248e-40 (rank : 36)	NC score	0.918000 (rank : 33)
Query Neighborhood Hits	451	Target Neighborhood Hits	326	Shared Neighborhood Hits	239
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI15_HUMAN
θ value	5.76516e-39 (rank : 37)	NC score	0.917762 (rank : 34)
Query Neighborhood Hits	451	Target Neighborhood Hits	395	Shared Neighborhood Hits	272
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI62_HUMAN
θ value	5.76516e-39 (rank : 38)	NC score	0.909843 (rank : 38)
Query Neighborhood Hits	451	Target Neighborhood Hits	584	Shared Neighborhood Hits	299
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI31_HUMAN
θ value	1.01765e-35 (rank : 39)	NC score	0.886890 (rank : 41)
Query Neighborhood Hits	451	Target Neighborhood Hits	299	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI62_MOUSE
θ value	1.73584e-35 (rank : 40)	NC score	0.914969 (rank : 35)
Query Neighborhood Hits	451	Target Neighborhood Hits	478	Shared Neighborhood Hits	278
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI35_HUMAN
θ value	2.86786e-30 (rank : 41)	NC score	0.909654 (rank : 39)
Query Neighborhood Hits	451	Target Neighborhood Hits	382	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	1.2049e-28 (rank : 42)	NC score	0.901847 (rank : 40)
Query Neighborhood Hits	451	Target Neighborhood Hits	465	Shared Neighborhood Hits	292
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

ERMAP_HUMAN
θ value	1.12775e-26 (rank : 43)	NC score	0.797025 (rank : 54)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	81
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	1.92365e-26 (rank : 44)	NC score	0.762015 (rank : 59)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

BT3A3_HUMAN
θ value	6.18819e-25 (rank : 45)	NC score	0.732854 (rank : 64)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL9_HUMAN
θ value	1.16704e-23 (rank : 46)	NC score	0.741331 (rank : 60)
Query Neighborhood Hits	451	Target Neighborhood Hits	125	Shared Neighborhood Hits	83
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT1A1_HUMAN
θ value	1.5242e-23 (rank : 47)	NC score	0.720156 (rank : 72)
Query Neighborhood Hits	451	Target Neighborhood Hits	322	Shared Neighborhood Hits	81
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	3.75424e-22 (rank : 48)	NC score	0.729378 (rank : 67)
Query Neighborhood Hits	451	Target Neighborhood Hits	252	Shared Neighborhood Hits	81
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A1_HUMAN
θ value	4.9032e-22 (rank : 49)	NC score	0.726268 (rank : 68)
Query Neighborhood Hits	451	Target Neighborhood Hits	229	Shared Neighborhood Hits	83
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BTNL3_HUMAN
θ value	4.9032e-22 (rank : 50)	NC score	0.736750 (rank : 61)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI73_HUMAN
θ value	7.0802e-21 (rank : 51)	NC score	0.831614 (rank : 46)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	213
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	1.5773e-20 (rank : 52)	NC score	0.830326 (rank : 47)
Query Neighborhood Hits	451	Target Neighborhood Hits	249	Shared Neighborhood Hits	207
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

BTNL8_HUMAN
θ value	2.06002e-20 (rank : 53)	NC score	0.718959 (rank : 73)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRI48_HUMAN
θ value	8.65492e-19 (rank : 54)	NC score	0.885208 (rank : 42)
Query Neighborhood Hits	451	Target Neighborhood Hits	192	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

BT2A2_HUMAN
θ value	1.47631e-18 (rank : 55)	NC score	0.734076 (rank : 62)
Query Neighborhood Hits	451	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A1_HUMAN
θ value	1.92812e-18 (rank : 56)	NC score	0.722409 (rank : 70)
Query Neighborhood Hits	451	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRI40_HUMAN
θ value	7.32683e-18 (rank : 57)	NC score	0.832274 (rank : 45)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	210
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI65_HUMAN
θ value	4.74913e-17 (rank : 58)	NC score	0.815930 (rank : 49)
Query Neighborhood Hits	451	Target Neighborhood Hits	330	Shared Neighborhood Hits	245
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RFPL3_HUMAN
θ value	8.10077e-17 (rank : 59)	NC score	0.814731 (rank : 50)
Query Neighborhood Hits	451	Target Neighborhood Hits	134	Shared Neighborhood Hits	123
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRI65_MOUSE
θ value	1.058e-16 (rank : 60)	NC score	0.802572 (rank : 52)
Query Neighborhood Hits	451	Target Neighborhood Hits	340	Shared Neighborhood Hits	244
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI13_HUMAN
θ value	4.02038e-16 (rank : 61)	NC score	0.770145 (rank : 57)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	207
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI14_HUMAN
θ value	5.25075e-16 (rank : 62)	NC score	0.772368 (rank : 55)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	120
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

RFPL2_HUMAN
θ value	1.16975e-15 (rank : 63)	NC score	0.802077 (rank : 53)
Query Neighborhood Hits	451	Target Neighborhood Hits	126	Shared Neighborhood Hits	113
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

BT2A3_HUMAN
θ value	1.52774e-15 (rank : 64)	NC score	0.720597 (rank : 71)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	77
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RFPL1_HUMAN
θ value	1.52774e-15 (rank : 65)	NC score	0.805363 (rank : 51)
Query Neighborhood Hits	451	Target Neighborhood Hits	119	Shared Neighborhood Hits	111
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI13_MOUSE
θ value	3.40345e-15 (rank : 66)	NC score	0.769728 (rank : 58)
Query Neighborhood Hits	451	Target Neighborhood Hits	282	Shared Neighborhood Hits	209
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

MEFV_MOUSE
θ value	1.86753e-13 (rank : 67)	NC score	0.705724 (rank : 74)
Query Neighborhood Hits	451	Target Neighborhood Hits	236	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI29_MOUSE
θ value	4.16044e-13 (rank : 68)	NC score	0.572619 (rank : 105)
Query Neighborhood Hits	451	Target Neighborhood Hits	306	Shared Neighborhood Hits	160
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI52_HUMAN
θ value	4.16044e-13 (rank : 69)	NC score	0.850939 (rank : 44)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	186
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI29_HUMAN
θ value	5.43371e-13 (rank : 70)	NC score	0.565070 (rank : 106)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	145
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI25_MOUSE
θ value	1.02475e-11 (rank : 71)	NC score	0.730798 (rank : 65)
Query Neighborhood Hits	451	Target Neighborhood Hits	446	Shared Neighborhood Hits	269
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI59_MOUSE
θ value	1.02475e-11 (rank : 72)	NC score	0.733855 (rank : 63)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	215
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI32_MOUSE
θ value	1.74796e-11 (rank : 73)	NC score	0.632400 (rank : 84)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	186
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI32_HUMAN
θ value	2.28291e-11 (rank : 74)	NC score	0.635959 (rank : 83)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	186
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI25_HUMAN
θ value	3.89403e-11 (rank : 75)	NC score	0.723767 (rank : 69)
Query Neighborhood Hits	451	Target Neighborhood Hits	472	Shared Neighborhood Hits	279
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI59_HUMAN
θ value	6.64225e-11 (rank : 76)	NC score	0.729586 (rank : 66)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	211
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRIM3_HUMAN
θ value	3.29651e-10 (rank : 77)	NC score	0.582774 (rank : 101)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	212
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	3.29651e-10 (rank : 78)	NC score	0.586133 (rank : 98)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	206
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM8_HUMAN
θ value	4.30538e-10 (rank : 79)	NC score	0.691754 (rank : 76)
Query Neighborhood Hits	451	Target Neighborhood Hits	650	Shared Neighborhood Hits	303
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	5.62301e-10 (rank : 80)	NC score	0.692071 (rank : 75)
Query Neighborhood Hits	451	Target Neighborhood Hits	674	Shared Neighborhood Hits	300
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI63_MOUSE
θ value	6.21693e-09 (rank : 81)	NC score	0.631953 (rank : 85)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	183
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM2_HUMAN
θ value	1.06045e-08 (rank : 82)	NC score	0.576418 (rank : 103)
Query Neighborhood Hits	451	Target Neighborhood Hits	330	Shared Neighborhood Hits	211
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	1.06045e-08 (rank : 83)	NC score	0.575273 (rank : 104)
Query Neighborhood Hits	451	Target Neighborhood Hits	331	Shared Neighborhood Hits	210
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI44_MOUSE
θ value	1.38499e-08 (rank : 84)	NC score	0.622123 (rank : 89)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI14_MOUSE
θ value	1.80886e-08 (rank : 85)	NC score	0.771206 (rank : 56)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI44_HUMAN
θ value	2.36244e-08 (rank : 86)	NC score	0.610507 (rank : 92)
Query Neighborhood Hits	451	Target Neighborhood Hits	393	Shared Neighborhood Hits	129
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI37_HUMAN
θ value	3.08544e-08 (rank : 87)	NC score	0.590639 (rank : 96)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	182
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	3.08544e-08 (rank : 88)	NC score	0.590271 (rank : 97)
Query Neighborhood Hits	451	Target Neighborhood Hits	316	Shared Neighborhood Hits	182
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI47_MOUSE
θ value	3.08544e-08 (rank : 89)	NC score	0.660808 (rank : 81)
Query Neighborhood Hits	451	Target Neighborhood Hits	295	Shared Neighborhood Hits	215
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI63_HUMAN
θ value	5.26297e-08 (rank : 90)	NC score	0.626280 (rank : 87)
Query Neighborhood Hits	451	Target Neighborhood Hits	298	Shared Neighborhood Hits	199
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI47_HUMAN
θ value	6.87365e-08 (rank : 91)	NC score	0.648233 (rank : 82)
Query Neighborhood Hits	451	Target Neighborhood Hits	286	Shared Neighborhood Hits	216
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI16_MOUSE
θ value	1.17247e-07 (rank : 92)	NC score	0.674041 (rank : 79)
Query Neighborhood Hits	451	Target Neighborhood Hits	196	Shared Neighborhood Hits	135
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI55_HUMAN
θ value	1.17247e-07 (rank : 93)	NC score	0.612278 (rank : 91)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	184
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

RNF39_HUMAN
θ value	1.53129e-07 (rank : 94)	NC score	0.817232 (rank : 48)
Query Neighborhood Hits	451	Target Neighborhood Hits	200	Shared Neighborhood Hits	182
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

BRCA1_HUMAN
θ value	1.99992e-07 (rank : 95)	NC score	0.542953 (rank : 107)
Query Neighborhood Hits	451	Target Neighborhood Hits	381	Shared Neighborhood Hits	210
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	7.59969e-07 (rank : 96)	NC score	0.527751 (rank : 109)
Query Neighborhood Hits	451	Target Neighborhood Hits	436	Shared Neighborhood Hits	199
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRIM1_HUMAN
θ value	2.21117e-06 (rank : 97)	NC score	0.599510 (rank : 94)
Query Neighborhood Hits	451	Target Neighborhood Hits	345	Shared Neighborhood Hits	238
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI54_HUMAN
θ value	4.92598e-06 (rank : 98)	NC score	0.585538 (rank : 99)
Query Neighborhood Hits	451	Target Neighborhood Hits	209	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	6.43352e-06 (rank : 99)	NC score	0.584664 (rank : 100)
Query Neighborhood Hits	451	Target Neighborhood Hits	197	Shared Neighborhood Hits	168
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI16_HUMAN
θ value	8.40245e-06 (rank : 100)	NC score	0.665248 (rank : 80)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BSPRY_MOUSE
θ value	1.09739e-05 (rank : 101)	NC score	0.690903 (rank : 77)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI18_HUMAN
θ value	1.09739e-05 (rank : 102)	NC score	0.628445 (rank : 86)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	219
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM1_MOUSE
θ value	1.87187e-05 (rank : 103)	NC score	0.595577 (rank : 95)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	239
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI18_MOUSE
θ value	2.44474e-05 (rank : 104)	NC score	0.613212 (rank : 90)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	221
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

BSPRY_HUMAN
θ value	3.19293e-05 (rank : 105)	NC score	0.688372 (rank : 78)
Query Neighborhood Hits	451	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RAG1_HUMAN
θ value	5.44631e-05 (rank : 106)	NC score	0.418512 (rank : 132)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	143
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

ZN313_MOUSE
θ value	7.1131e-05 (rank : 107)	NC score	0.527518 (rank : 110)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	185
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ZN313_HUMAN
θ value	9.29e-05 (rank : 108)	NC score	0.517849 (rank : 112)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ANR26_HUMAN
θ value	0.000121331 (rank : 109)	NC score	0.080348 (rank : 313)
Query Neighborhood Hits	451	Target Neighborhood Hits	1614	Shared Neighborhood Hits	224
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RN125_MOUSE
θ value	0.000121331 (rank : 110)	NC score	0.523538 (rank : 111)
Query Neighborhood Hits	451	Target Neighborhood Hits	220	Shared Neighborhood Hits	162
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI46_MOUSE
θ value	0.000158464 (rank : 111)	NC score	0.481779 (rank : 120)
Query Neighborhood Hits	451	Target Neighborhood Hits	287	Shared Neighborhood Hits	195
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RN125_HUMAN
θ value	0.00020696 (rank : 112)	NC score	0.510018 (rank : 115)
Query Neighborhood Hits	451	Target Neighborhood Hits	230	Shared Neighborhood Hits	171
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRAF6_MOUSE
θ value	0.000270298 (rank : 113)	NC score	0.366342 (rank : 144)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	176
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI56_HUMAN
θ value	0.000270298 (rank : 114)	NC score	0.446121 (rank : 125)
Query Neighborhood Hits	451	Target Neighborhood Hits	339	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

RING1_HUMAN
θ value	0.00035302 (rank : 115)	NC score	0.437744 (rank : 129)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	156
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.00035302 (rank : 116)	NC score	0.430691 (rank : 131)
Query Neighborhood Hits	451	Target Neighborhood Hits	220	Shared Neighborhood Hits	156
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	0.00035302 (rank : 117)	NC score	0.408754 (rank : 134)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	152
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.00035302 (rank : 118)	NC score	0.408822 (rank : 133)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

ZN179_HUMAN
θ value	0.00035302 (rank : 119)	NC score	0.623491 (rank : 88)
Query Neighborhood Hits	451	Target Neighborhood Hits	178	Shared Neighborhood Hits	151
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

LNX1_MOUSE
θ value	0.000461057 (rank : 120)	NC score	0.262615 (rank : 174)
Query Neighborhood Hits	451	Target Neighborhood Hits	377	Shared Neighborhood Hits	157
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RN166_HUMAN
θ value	0.000602161 (rank : 121)	NC score	0.507279 (rank : 117)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	176
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI42_HUMAN
θ value	0.000602161 (rank : 122)	NC score	0.358944 (rank : 148)
Query Neighborhood Hits	451	Target Neighborhood Hits	283	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BFAR_HUMAN
θ value	0.00102713 (rank : 123)	NC score	0.531648 (rank : 108)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN168_HUMAN
θ value	0.00102713 (rank : 124)	NC score	0.515129 (rank : 114)
Query Neighborhood Hits	451	Target Neighborhood Hits	370	Shared Neighborhood Hits	206
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TIF1G_HUMAN
θ value	0.00102713 (rank : 125)	NC score	0.281463 (rank : 169)
Query Neighborhood Hits	451	Target Neighborhood Hits	410	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

UB7I3_MOUSE
θ value	0.00102713 (rank : 126)	NC score	0.158210 (rank : 230)
Query Neighborhood Hits	451	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

MIB1_HUMAN
θ value	0.00134147 (rank : 127)	NC score	0.095858 (rank : 266)
Query Neighborhood Hits	451	Target Neighborhood Hits	470	Shared Neighborhood Hits	97
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.00134147 (rank : 128)	NC score	0.095673 (rank : 268)
Query Neighborhood Hits	451	Target Neighborhood Hits	471	Shared Neighborhood Hits	97
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PEX10_HUMAN
θ value	0.00134147 (rank : 129)	NC score	0.508306 (rank : 116)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	170
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF41_HUMAN
θ value	0.00134147 (rank : 130)	NC score	0.408410 (rank : 136)
Query Neighborhood Hits	451	Target Neighborhood Hits	226	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.00134147 (rank : 131)	NC score	0.408723 (rank : 135)
Query Neighborhood Hits	451	Target Neighborhood Hits	224	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SMRA3_HUMAN
θ value	0.00134147 (rank : 132)	NC score	0.304186 (rank : 161)
Query Neighborhood Hits	451	Target Neighborhood Hits	265	Shared Neighborhood Hits	175
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	0.00134147 (rank : 133)	NC score	0.287049 (rank : 168)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	166
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TIF1G_MOUSE
θ value	0.00134147 (rank : 134)	NC score	0.276949 (rank : 170)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	131
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI46_HUMAN
θ value	0.00134147 (rank : 135)	NC score	0.480119 (rank : 121)
Query Neighborhood Hits	451	Target Neighborhood Hits	291	Shared Neighborhood Hits	196
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

LMNB2_MOUSE
θ value	0.00175202 (rank : 136)	NC score	0.038109 (rank : 653)
Query Neighborhood Hits	451	Target Neighborhood Hits	674	Shared Neighborhood Hits	150
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LNX1_HUMAN
θ value	0.00175202 (rank : 137)	NC score	0.260357 (rank : 175)
Query Neighborhood Hits	451	Target Neighborhood Hits	379	Shared Neighborhood Hits	165
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_MOUSE
θ value	0.00175202 (rank : 138)	NC score	0.254421 (rank : 180)
Query Neighborhood Hits	451	Target Neighborhood Hits	407	Shared Neighborhood Hits	173
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RN166_MOUSE
θ value	0.00175202 (rank : 139)	NC score	0.498359 (rank : 118)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	180
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI36_MOUSE
θ value	0.00175202 (rank : 140)	NC score	0.443478 (rank : 126)
Query Neighborhood Hits	451	Target Neighborhood Hits	266	Shared Neighborhood Hits	187
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

LNX2_HUMAN
θ value	0.00228821 (rank : 141)	NC score	0.253410 (rank : 181)
Query Neighborhood Hits	451	Target Neighborhood Hits	389	Shared Neighborhood Hits	172
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TRI36_HUMAN
θ value	0.00228821 (rank : 142)	NC score	0.453389 (rank : 123)
Query Neighborhood Hits	451	Target Neighborhood Hits	282	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

CT2NL_HUMAN
θ value	0.00298849 (rank : 143)	NC score	0.091587 (rank : 279)
Query Neighborhood Hits	451	Target Neighborhood Hits	1059	Shared Neighborhood Hits	184
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RFWD2_HUMAN
θ value	0.00298849 (rank : 144)	NC score	0.295610 (rank : 165)
Query Neighborhood Hits	451	Target Neighborhood Hits	518	Shared Neighborhood Hits	188
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRAF6_HUMAN
θ value	0.00298849 (rank : 145)	NC score	0.354688 (rank : 151)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI56_MOUSE
θ value	0.00298849 (rank : 146)	NC score	0.442944 (rank : 127)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

RNF8_MOUSE
θ value	0.00390308 (rank : 147)	NC score	0.464809 (rank : 122)
Query Neighborhood Hits	451	Target Neighborhood Hits	618	Shared Neighborhood Hits	297
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

BFAR_MOUSE
θ value	0.00509761 (rank : 148)	NC score	0.517243 (rank : 113)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RNF8_HUMAN
θ value	0.00509761 (rank : 149)	NC score	0.446516 (rank : 124)
Query Neighborhood Hits	451	Target Neighborhood Hits	622	Shared Neighborhood Hits	288
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

T3JAM_HUMAN
θ value	0.00509761 (rank : 150)	NC score	0.080335 (rank : 314)
Query Neighborhood Hits	451	Target Neighborhood Hits	533	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

RAG1_MOUSE
θ value	0.00665767 (rank : 151)	NC score	0.405044 (rank : 137)
Query Neighborhood Hits	451	Target Neighborhood Hits	189	Shared Neighborhood Hits	144
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RN168_MOUSE
θ value	0.00665767 (rank : 152)	NC score	0.496154 (rank : 119)
Query Neighborhood Hits	451	Target Neighborhood Hits	440	Shared Neighborhood Hits	227
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI42_MOUSE
θ value	0.00665767 (rank : 153)	NC score	0.357369 (rank : 149)
Query Neighborhood Hits	451	Target Neighborhood Hits	316	Shared Neighborhood Hits	134
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

PZRN4_HUMAN
θ value	0.00869519 (rank : 154)	NC score	0.218661 (rank : 194)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	184
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RFWD2_MOUSE
θ value	0.00869519 (rank : 155)	NC score	0.295611 (rank : 164)
Query Neighborhood Hits	451	Target Neighborhood Hits	535	Shared Neighborhood Hits	192
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

CCD46_HUMAN
θ value	0.0113563 (rank : 156)	NC score	0.095683 (rank : 267)
Query Neighborhood Hits	451	Target Neighborhood Hits	1430	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

EP15R_MOUSE
θ value	0.0113563 (rank : 157)	NC score	0.080240 (rank : 316)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	194
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

CENPF_HUMAN
θ value	0.0148317 (rank : 158)	NC score	0.090519 (rank : 281)
Query Neighborhood Hits	451	Target Neighborhood Hits	1932	Shared Neighborhood Hits	258
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

RN169_HUMAN
θ value	0.0148317 (rank : 159)	NC score	0.373292 (rank : 141)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	110
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

CM007_MOUSE
θ value	0.0193708 (rank : 160)	NC score	0.293745 (rank : 166)
Query Neighborhood Hits	451	Target Neighborhood Hits	416	Shared Neighborhood Hits	190
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CT2NL_MOUSE
θ value	0.0193708 (rank : 161)	NC score	0.085187 (rank : 297)
Query Neighborhood Hits	451	Target Neighborhood Hits	902	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RBBP6_HUMAN
θ value	0.0193708 (rank : 162)	NC score	0.176989 (rank : 217)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	187
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.0193708 (rank : 163)	NC score	0.191365 (rank : 205)
Query Neighborhood Hits	451	Target Neighborhood Hits	1014	Shared Neighborhood Hits	176
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_HUMAN
θ value	0.0193708 (rank : 164)	NC score	0.214970 (rank : 196)
Query Neighborhood Hits	451	Target Neighborhood Hits	433	Shared Neighborhood Hits	132
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CCD41_MOUSE
θ value	0.0252991 (rank : 165)	NC score	0.088054 (rank : 290)
Query Neighborhood Hits	451	Target Neighborhood Hits	1399	Shared Neighborhood Hits	219
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DESP_HUMAN
θ value	0.0252991 (rank : 166)	NC score	0.069439 (rank : 391)
Query Neighborhood Hits	451	Target Neighborhood Hits	1470	Shared Neighborhood Hits	222
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EP15R_HUMAN
θ value	0.0252991 (rank : 167)	NC score	0.080812 (rank : 312)
Query Neighborhood Hits	451	Target Neighborhood Hits	1083	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

PZRN3_HUMAN
θ value	0.0252991 (rank : 168)	NC score	0.221220 (rank : 193)
Query Neighborhood Hits	451	Target Neighborhood Hits	461	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.0252991 (rank : 169)	NC score	0.223347 (rank : 192)
Query Neighborhood Hits	451	Target Neighborhood Hits	447	Shared Neighborhood Hits	179
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RC3H1_MOUSE
θ value	0.0252991 (rank : 170)	NC score	0.224413 (rank : 190)
Query Neighborhood Hits	451	Target Neighborhood Hits	244	Shared Neighborhood Hits	129
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

CLC4M_HUMAN
θ value	0.0330416 (rank : 171)	NC score	0.018847 (rank : 686)
Query Neighborhood Hits	451	Target Neighborhood Hits	291	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

CM007_HUMAN
θ value	0.0330416 (rank : 172)	NC score	0.266177 (rank : 173)
Query Neighborhood Hits	451	Target Neighborhood Hits	422	Shared Neighborhood Hits	196
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

FES_MOUSE
θ value	0.0330416 (rank : 173)	NC score	-0.001560 (rank : 715)
Query Neighborhood Hits	451	Target Neighborhood Hits	980	Shared Neighborhood Hits	61
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

GCC1_HUMAN
θ value	0.0330416 (rank : 174)	NC score	0.094667 (rank : 269)
Query Neighborhood Hits	451	Target Neighborhood Hits	887	Shared Neighborhood Hits	187
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TIF1A_HUMAN
θ value	0.0330416 (rank : 175)	NC score	0.190301 (rank : 206)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	111
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRIM9_HUMAN
θ value	0.0330416 (rank : 176)	NC score	0.438899 (rank : 128)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	179
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.0330416 (rank : 177)	NC score	0.435241 (rank : 130)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	178
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

UHRF1_MOUSE
θ value	0.0330416 (rank : 178)	NC score	0.258631 (rank : 177)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	158
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ARD1_MOUSE
θ value	0.0431538 (rank : 179)	NC score	0.131316 (rank : 237)
Query Neighborhood Hits	451	Target Neighborhood Hits	573	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

M4K4_HUMAN
θ value	0.0431538 (rank : 180)	NC score	0.016248 (rank : 692)
Query Neighborhood Hits	451	Target Neighborhood Hits	1589	Shared Neighborhood Hits	171
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	0.0431538 (rank : 181)	NC score	0.015695 (rank : 693)
Query Neighborhood Hits	451	Target Neighborhood Hits	1560	Shared Neighborhood Hits	157
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

RNF4_HUMAN
θ value	0.0431538 (rank : 182)	NC score	0.388715 (rank : 138)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	155
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.0431538 (rank : 183)	NC score	0.382379 (rank : 139)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	156
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI45_HUMAN
θ value	0.0431538 (rank : 184)	NC score	0.276012 (rank : 171)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

UHRF2_HUMAN
θ value	0.0431538 (rank : 185)	NC score	0.304430 (rank : 160)
Query Neighborhood Hits	451	Target Neighborhood Hits	269	Shared Neighborhood Hits	159
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	0.0431538 (rank : 186)	NC score	0.299555 (rank : 162)
Query Neighborhood Hits	451	Target Neighborhood Hits	275	Shared Neighborhood Hits	158
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ANR26_MOUSE
θ value	0.0563607 (rank : 187)	NC score	0.070097 (rank : 384)
Query Neighborhood Hits	451	Target Neighborhood Hits	1554	Shared Neighborhood Hits	222
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MAT1_HUMAN
θ value	0.0563607 (rank : 188)	NC score	0.173071 (rank : 222)
Query Neighborhood Hits	451	Target Neighborhood Hits	179	Shared Neighborhood Hits	95
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	0.0563607 (rank : 189)	NC score	0.174157 (rank : 219)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	106
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MX1_MOUSE
θ value	0.0563607 (rank : 190)	NC score	0.012764 (rank : 695)
Query Neighborhood Hits	451	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

RAD18_HUMAN
θ value	0.0563607 (rank : 191)	NC score	0.298278 (rank : 163)
Query Neighborhood Hits	451	Target Neighborhood Hits	284	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	0.0563607 (rank : 192)	NC score	0.325760 (rank : 155)
Query Neighborhood Hits	451	Target Neighborhood Hits	230	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

STK10_MOUSE
θ value	0.0563607 (rank : 193)	NC score	0.025246 (rank : 673)
Query Neighborhood Hits	451	Target Neighborhood Hits	2132	Shared Neighborhood Hits	207
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYH11_MOUSE
θ value	0.0736092 (rank : 194)	NC score	0.072275 (rank : 367)
Query Neighborhood Hits	451	Target Neighborhood Hits	1777	Shared Neighborhood Hits	245
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RN141_HUMAN
θ value	0.0736092 (rank : 195)	NC score	0.306056 (rank : 158)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.0736092 (rank : 196)	NC score	0.305058 (rank : 159)
Query Neighborhood Hits	451	Target Neighborhood Hits	200	Shared Neighborhood Hits	144
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	0.0736092 (rank : 197)	NC score	0.332514 (rank : 152)
Query Neighborhood Hits	451	Target Neighborhood Hits	162	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.0736092 (rank : 198)	NC score	0.330277 (rank : 153)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

UB7I3_HUMAN
θ value	0.0736092 (rank : 199)	NC score	0.135415 (rank : 234)
Query Neighborhood Hits	451	Target Neighborhood Hits	136	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

BICD1_MOUSE
θ value	0.0961366 (rank : 200)	NC score	0.057861 (rank : 517)
Query Neighborhood Hits	451	Target Neighborhood Hits	837	Shared Neighborhood Hits	182
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCD19_HUMAN
θ value	0.0961366 (rank : 201)	NC score	0.081313 (rank : 310)
Query Neighborhood Hits	451	Target Neighborhood Hits	639	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

RN103_HUMAN
θ value	0.0961366 (rank : 202)	NC score	0.093547 (rank : 272)
Query Neighborhood Hits	451	Target Neighborhood Hits	153	Shared Neighborhood Hits	65
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.0961366 (rank : 203)	NC score	0.093348 (rank : 273)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

SMC1A_HUMAN
θ value	0.0961366 (rank : 204)	NC score	0.075337 (rank : 339)
Query Neighborhood Hits	451	Target Neighborhood Hits	1346	Shared Neighborhood Hits	213
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.0961366 (rank : 205)	NC score	0.074347 (rank : 345)
Query Neighborhood Hits	451	Target Neighborhood Hits	1384	Shared Neighborhood Hits	217
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

UHRF1_HUMAN
θ value	0.0961366 (rank : 206)	NC score	0.248375 (rank : 183)
Query Neighborhood Hits	451	Target Neighborhood Hits	272	Shared Neighborhood Hits	160
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ARD1_HUMAN
θ value	0.125558 (rank : 207)	NC score	0.126448 (rank : 245)
Query Neighborhood Hits	451	Target Neighborhood Hits	621	Shared Neighborhood Hits	88
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

BARD1_HUMAN
θ value	0.125558 (rank : 208)	NC score	0.145090 (rank : 231)
Query Neighborhood Hits	451	Target Neighborhood Hits	427	Shared Neighborhood Hits	105
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CHFR_HUMAN
θ value	0.125558 (rank : 209)	NC score	0.363197 (rank : 145)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	166
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.125558 (rank : 210)	NC score	0.357044 (rank : 150)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	167
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

LAMA2_HUMAN
θ value	0.125558 (rank : 211)	NC score	0.020688 (rank : 680)
Query Neighborhood Hits	451	Target Neighborhood Hits	1092	Shared Neighborhood Hits	127
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

STK10_HUMAN
θ value	0.125558 (rank : 212)	NC score	0.020479 (rank : 681)
Query Neighborhood Hits	451	Target Neighborhood Hits	1921	Shared Neighborhood Hits	192
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BARD1_MOUSE
θ value	0.163984 (rank : 213)	NC score	0.143599 (rank : 232)
Query Neighborhood Hits	451	Target Neighborhood Hits	411	Shared Neighborhood Hits	103
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CCD41_HUMAN
θ value	0.163984 (rank : 214)	NC score	0.085355 (rank : 296)
Query Neighborhood Hits	451	Target Neighborhood Hits	1139	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CENPE_HUMAN
θ value	0.163984 (rank : 215)	NC score	0.081943 (rank : 308)
Query Neighborhood Hits	451	Target Neighborhood Hits	2060	Shared Neighborhood Hits	257
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

IDLC_MOUSE
θ value	0.163984 (rank : 216)	NC score	0.054679 (rank : 560)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

TOPRS_HUMAN
θ value	0.163984 (rank : 217)	NC score	0.212538 (rank : 197)
Query Neighborhood Hits	451	Target Neighborhood Hits	286	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.163984 (rank : 218)	NC score	0.215791 (rank : 195)
Query Neighborhood Hits	451	Target Neighborhood Hits	263	Shared Neighborhood Hits	130
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRHY_HUMAN
θ value	0.163984 (rank : 219)	NC score	0.081957 (rank : 307)
Query Neighborhood Hits	451	Target Neighborhood Hits	1385	Shared Neighborhood Hits	196
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CAR11_HUMAN
θ value	0.21417 (rank : 220)	NC score	0.052327 (rank : 598)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CK5P2_HUMAN
θ value	0.21417 (rank : 221)	NC score	0.068518 (rank : 398)
Query Neighborhood Hits	451	Target Neighborhood Hits	1433	Shared Neighborhood Hits	208
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

ENKUR_HUMAN
θ value	0.21417 (rank : 222)	NC score	0.046311 (rank : 643)
Query Neighborhood Hits	451	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

EP15_HUMAN
θ value	0.21417 (rank : 223)	NC score	0.074880 (rank : 341)
Query Neighborhood Hits	451	Target Neighborhood Hits	1021	Shared Neighborhood Hits	181
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

IDLC_HUMAN
θ value	0.21417 (rank : 224)	NC score	0.055803 (rank : 549)
Query Neighborhood Hits	451	Target Neighborhood Hits	348	Shared Neighborhood Hits	107
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

INCE_HUMAN
θ value	0.21417 (rank : 225)	NC score	0.087832 (rank : 291)
Query Neighborhood Hits	451	Target Neighborhood Hits	978	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MRCKB_MOUSE
θ value	0.21417 (rank : 226)	NC score	0.029326 (rank : 664)
Query Neighborhood Hits	451	Target Neighborhood Hits	2180	Shared Neighborhood Hits	221
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH11_HUMAN
θ value	0.21417 (rank : 227)	NC score	0.073442 (rank : 354)
Query Neighborhood Hits	451	Target Neighborhood Hits	1806	Shared Neighborhood Hits	250
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO6_HUMAN
θ value	0.21417 (rank : 228)	NC score	0.046634 (rank : 642)
Query Neighborhood Hits	451	Target Neighborhood Hits	727	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

PCGF6_MOUSE
θ value	0.21417 (rank : 229)	NC score	0.256964 (rank : 178)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	124
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

BIRC7_HUMAN
θ value	0.279714 (rank : 230)	NC score	0.289345 (rank : 167)
Query Neighborhood Hits	451	Target Neighborhood Hits	185	Shared Neighborhood Hits	130
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

DTX3_MOUSE
θ value	0.279714 (rank : 231)	NC score	0.327154 (rank : 154)
Query Neighborhood Hits	451	Target Neighborhood Hits	202	Shared Neighborhood Hits	149
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

GOGA4_MOUSE
θ value	0.279714 (rank : 232)	NC score	0.093810 (rank : 271)
Query Neighborhood Hits	451	Target Neighborhood Hits	1939	Shared Neighborhood Hits	259
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

IF2M_MOUSE
θ value	0.279714 (rank : 233)	NC score	0.018266 (rank : 689)
Query Neighborhood Hits	451	Target Neighborhood Hits	183	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

KIF5C_MOUSE
θ value	0.279714 (rank : 234)	NC score	0.051014 (rank : 618)
Query Neighborhood Hits	451	Target Neighborhood Hits	1040	Shared Neighborhood Hits	191
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MYO6_MOUSE
θ value	0.279714 (rank : 235)	NC score	0.043770 (rank : 647)
Query Neighborhood Hits	451	Target Neighborhood Hits	586	Shared Neighborhood Hits	151
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

SPRY4_MOUSE
θ value	0.279714 (rank : 236)	NC score	0.604900 (rank : 93)
Query Neighborhood Hits	451	Target Neighborhood Hits	82	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SYCP1_MOUSE
θ value	0.279714 (rank : 237)	NC score	0.088934 (rank : 286)
Query Neighborhood Hits	451	Target Neighborhood Hits	1456	Shared Neighborhood Hits	235
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DYNA_MOUSE
θ value	0.365318 (rank : 238)	NC score	0.068038 (rank : 402)
Query Neighborhood Hits	451	Target Neighborhood Hits	1084	Shared Neighborhood Hits	189
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

HC127_HUMAN
θ value	0.365318 (rank : 239)	NC score	0.046180 (rank : 644)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	0.365318 (rank : 240)	NC score	0.046180 (rank : 645)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	88
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

LRSM1_MOUSE
θ value	0.365318 (rank : 241)	NC score	0.076193 (rank : 335)
Query Neighborhood Hits	451	Target Neighborhood Hits	874	Shared Neighborhood Hits	201
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MRCKB_HUMAN
θ value	0.365318 (rank : 242)	NC score	0.030784 (rank : 663)
Query Neighborhood Hits	451	Target Neighborhood Hits	2239	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PCNT_MOUSE
θ value	0.365318 (rank : 243)	NC score	0.079385 (rank : 320)
Query Neighborhood Hits	451	Target Neighborhood Hits	1207	Shared Neighborhood Hits	220
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RNF5_MOUSE
θ value	0.365318 (rank : 244)	NC score	0.361947 (rank : 147)
Query Neighborhood Hits	451	Target Neighborhood Hits	206	Shared Neighborhood Hits	145
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TIF1A_MOUSE
θ value	0.365318 (rank : 245)	NC score	0.162763 (rank : 226)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	97
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BSN_HUMAN
θ value	0.47712 (rank : 246)	NC score	0.037363 (rank : 655)
Query Neighborhood Hits	451	Target Neighborhood Hits	1537	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DTX3L_HUMAN
θ value	0.47712 (rank : 247)	NC score	0.161785 (rank : 228)
Query Neighborhood Hits	451	Target Neighborhood Hits	187	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	0.47712 (rank : 248)	NC score	0.314805 (rank : 157)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

GOGA4_HUMAN
θ value	0.47712 (rank : 249)	NC score	0.087289 (rank : 292)
Query Neighborhood Hits	451	Target Neighborhood Hits	2034	Shared Neighborhood Hits	266
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KIF6_HUMAN
θ value	0.47712 (rank : 250)	NC score	0.019518 (rank : 684)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	81
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

MIB2_HUMAN
θ value	0.47712 (rank : 251)	NC score	0.078675 (rank : 324)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	91
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MYH9_HUMAN
θ value	0.47712 (rank : 252)	NC score	0.067046 (rank : 411)
Query Neighborhood Hits	451	Target Neighborhood Hits	1762	Shared Neighborhood Hits	247
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NUMA1_HUMAN
θ value	0.47712 (rank : 253)	NC score	0.084405 (rank : 298)
Query Neighborhood Hits	451	Target Neighborhood Hits	1523	Shared Neighborhood Hits	226
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PHLB1_HUMAN
θ value	0.47712 (rank : 254)	NC score	0.052118 (rank : 603)
Query Neighborhood Hits	451	Target Neighborhood Hits	1038	Shared Neighborhood Hits	161
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RNF5_HUMAN
θ value	0.47712 (rank : 255)	NC score	0.362746 (rank : 146)
Query Neighborhood Hits	451	Target Neighborhood Hits	206	Shared Neighborhood Hits	146
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

T3JAM_MOUSE
θ value	0.47712 (rank : 256)	NC score	0.062106 (rank : 465)
Query Neighborhood Hits	451	Target Neighborhood Hits	535	Shared Neighborhood Hits	135
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TRAF3_MOUSE
θ value	0.47712 (rank : 257)	NC score	0.189890 (rank : 207)
Query Neighborhood Hits	451	Target Neighborhood Hits	476	Shared Neighborhood Hits	209
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

ACTN3_HUMAN
θ value	0.62314 (rank : 258)	NC score	0.011507 (rank : 700)
Query Neighborhood Hits	451	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

CCD11_HUMAN
θ value	0.62314 (rank : 259)	NC score	0.072898 (rank : 364)
Query Neighborhood Hits	451	Target Neighborhood Hits	822	Shared Neighborhood Hits	179
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CTGE5_MOUSE
θ value	0.62314 (rank : 260)	NC score	0.071704 (rank : 372)
Query Neighborhood Hits	451	Target Neighborhood Hits	928	Shared Neighborhood Hits	185
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DYNA_HUMAN
θ value	0.62314 (rank : 261)	NC score	0.070874 (rank : 377)
Query Neighborhood Hits	451	Target Neighborhood Hits	1194	Shared Neighborhood Hits	204
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

EP15_MOUSE
θ value	0.62314 (rank : 262)	NC score	0.073497 (rank : 353)
Query Neighborhood Hits	451	Target Neighborhood Hits	820	Shared Neighborhood Hits	167
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GOGA5_HUMAN
θ value	0.62314 (rank : 263)	NC score	0.060344 (rank : 490)
Query Neighborhood Hits	451	Target Neighborhood Hits	1168	Shared Neighborhood Hits	192
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

ITSN1_MOUSE
θ value	0.62314 (rank : 264)	NC score	0.047161 (rank : 640)
Query Neighborhood Hits	451	Target Neighborhood Hits	1669	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MYO5A_MOUSE
θ value	0.62314 (rank : 265)	NC score	0.051534 (rank : 610)
Query Neighborhood Hits	451	Target Neighborhood Hits	1117	Shared Neighborhood Hits	198
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

PCNT_HUMAN
θ value	0.62314 (rank : 266)	NC score	0.090330 (rank : 282)
Query Neighborhood Hits	451	Target Neighborhood Hits	1551	Shared Neighborhood Hits	228
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RNH2B_MOUSE
θ value	0.62314 (rank : 267)	NC score	0.016325 (rank : 691)
Query Neighborhood Hits	451	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZV0, Q9D014	Gene names	Dleu8, Rnaseh2b
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) (Deleted in lymphocytic leukemia 8 homolog).

TIF1B_HUMAN
θ value	0.62314 (rank : 268)	NC score	0.240358 (rank : 186)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	117
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRAF3_HUMAN
θ value	0.62314 (rank : 269)	NC score	0.181917 (rank : 213)
Query Neighborhood Hits	451	Target Neighborhood Hits	463	Shared Neighborhood Hits	202
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF4_HUMAN
θ value	0.62314 (rank : 270)	NC score	0.223418 (rank : 191)
Query Neighborhood Hits	451	Target Neighborhood Hits	373	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_HUMAN
θ value	0.62314 (rank : 271)	NC score	0.229858 (rank : 188)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	193
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

ACTN3_MOUSE
θ value	0.813845 (rank : 272)	NC score	0.011979 (rank : 698)
Query Neighborhood Hits	451	Target Neighborhood Hits	265	Shared Neighborhood Hits	64
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

BRAP_HUMAN
θ value	0.813845 (rank : 273)	NC score	0.127478 (rank : 244)
Query Neighborhood Hits	451	Target Neighborhood Hits	560	Shared Neighborhood Hits	186
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BSN_MOUSE
θ value	0.813845 (rank : 274)	NC score	0.026671 (rank : 671)
Query Neighborhood Hits	451	Target Neighborhood Hits	2057	Shared Neighborhood Hits	133
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CUTL1_MOUSE
θ value	0.813845 (rank : 275)	NC score	0.064764 (rank : 435)
Query Neighborhood Hits	451	Target Neighborhood Hits	1620	Shared Neighborhood Hits	205
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ENKUR_MOUSE
θ value	0.813845 (rank : 276)	NC score	0.032191 (rank : 662)
Query Neighborhood Hits	451	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

HMMR_MOUSE
θ value	0.813845 (rank : 277)	NC score	0.073383 (rank : 357)
Query Neighborhood Hits	451	Target Neighborhood Hits	1178	Shared Neighborhood Hits	207
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

KINH_HUMAN
θ value	0.813845 (rank : 278)	NC score	0.053458 (rank : 576)
Query Neighborhood Hits	451	Target Neighborhood Hits	1231	Shared Neighborhood Hits	197
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MYH9_MOUSE
θ value	0.813845 (rank : 279)	NC score	0.068383 (rank : 399)
Query Neighborhood Hits	451	Target Neighborhood Hits	1829	Shared Neighborhood Hits	245
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PCGF4_HUMAN
θ value	0.813845 (rank : 280)	NC score	0.211788 (rank : 199)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	113
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.813845 (rank : 281)	NC score	0.212165 (rank : 198)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RN183_HUMAN
θ value	0.813845 (rank : 282)	NC score	0.375348 (rank : 140)
Query Neighborhood Hits	451	Target Neighborhood Hits	126	Shared Neighborhood Hits	111
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

SMC2_HUMAN
θ value	0.813845 (rank : 283)	NC score	0.072712 (rank : 366)
Query Neighborhood Hits	451	Target Neighborhood Hits	1405	Shared Neighborhood Hits	206
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TIF1B_MOUSE
θ value	0.813845 (rank : 284)	NC score	0.234989 (rank : 187)
Query Neighborhood Hits	451	Target Neighborhood Hits	276	Shared Neighborhood Hits	112
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRAF5_MOUSE
θ value	0.813845 (rank : 285)	NC score	0.255222 (rank : 179)
Query Neighborhood Hits	451	Target Neighborhood Hits	355	Shared Neighborhood Hits	192
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

BRAP_MOUSE
θ value	1.06291 (rank : 286)	NC score	0.111243 (rank : 255)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	153
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CE152_HUMAN
θ value	1.06291 (rank : 287)	NC score	0.070067 (rank : 387)
Query Neighborhood Hits	451	Target Neighborhood Hits	976	Shared Neighborhood Hits	185
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CNOT4_HUMAN
θ value	1.06291 (rank : 288)	NC score	0.117602 (rank : 251)
Query Neighborhood Hits	451	Target Neighborhood Hits	207	Shared Neighborhood Hits	44
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	1.06291 (rank : 289)	NC score	0.112137 (rank : 254)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CP250_HUMAN
θ value	1.06291 (rank : 290)	NC score	0.092233 (rank : 278)
Query Neighborhood Hits	451	Target Neighborhood Hits	1805	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GBP1_MOUSE
θ value	1.06291 (rank : 291)	NC score	0.028752 (rank : 665)
Query Neighborhood Hits	451	Target Neighborhood Hits	302	Shared Neighborhood Hits	99
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

KIF4A_MOUSE
θ value	1.06291 (rank : 292)	NC score	0.047643 (rank : 638)
Query Neighborhood Hits	451	Target Neighborhood Hits	1033	Shared Neighborhood Hits	190
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KINH_MOUSE
θ value	1.06291 (rank : 293)	NC score	0.052184 (rank : 602)
Query Neighborhood Hits	451	Target Neighborhood Hits	1082	Shared Neighborhood Hits	194
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LAMA2_MOUSE
θ value	1.06291 (rank : 294)	NC score	0.025240 (rank : 674)
Query Neighborhood Hits	451	Target Neighborhood Hits	1198	Shared Neighborhood Hits	141
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

M4K1_HUMAN
θ value	1.06291 (rank : 295)	NC score	-0.002205 (rank : 716)
Query Neighborhood Hits	451	Target Neighborhood Hits	884	Shared Neighborhood Hits	21
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

MIB2_MOUSE
θ value	1.06291 (rank : 296)	NC score	0.072130 (rank : 370)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

NGAP_HUMAN
θ value	1.06291 (rank : 297)	NC score	0.036558 (rank : 657)
Query Neighborhood Hits	451	Target Neighborhood Hits	517	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

PCGF6_HUMAN
θ value	1.06291 (rank : 298)	NC score	0.251236 (rank : 182)
Query Neighborhood Hits	451	Target Neighborhood Hits	178	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RN185_HUMAN
θ value	1.06291 (rank : 299)	NC score	0.370993 (rank : 142)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	151
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	1.06291 (rank : 300)	NC score	0.370535 (rank : 143)
Query Neighborhood Hits	451	Target Neighborhood Hits	211	Shared Neighborhood Hits	151
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI45_MOUSE
θ value	1.06291 (rank : 301)	NC score	0.259110 (rank : 176)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	112
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

CCD91_HUMAN
θ value	1.38821 (rank : 302)	NC score	0.073976 (rank : 349)
Query Neighborhood Hits	451	Target Neighborhood Hits	868	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

KIF5C_HUMAN
θ value	1.38821 (rank : 303)	NC score	0.048834 (rank : 636)
Query Neighborhood Hits	451	Target Neighborhood Hits	974	Shared Neighborhood Hits	183
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KTN1_MOUSE
θ value	1.38821 (rank : 304)	NC score	0.071071 (rank : 376)
Query Neighborhood Hits	451	Target Neighborhood Hits	1324	Shared Neighborhood Hits	224
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYO5A_HUMAN
θ value	1.38821 (rank : 305)	NC score	0.048738 (rank : 637)
Query Neighborhood Hits	451	Target Neighborhood Hits	1092	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

PLCB3_HUMAN
θ value	1.38821 (rank : 306)	NC score	0.036753 (rank : 656)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	108
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

ROCK2_HUMAN
θ value	1.38821 (rank : 307)	NC score	0.028283 (rank : 666)
Query Neighborhood Hits	451	Target Neighborhood Hits	2073	Shared Neighborhood Hits	219
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SYCP3_HUMAN
θ value	1.38821 (rank : 308)	NC score	0.061385 (rank : 474)
Query Neighborhood Hits	451	Target Neighborhood Hits	276	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

TRAF7_HUMAN
θ value	1.38821 (rank : 309)	NC score	0.183661 (rank : 210)
Query Neighborhood Hits	451	Target Neighborhood Hits	482	Shared Neighborhood Hits	162
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	1.38821 (rank : 310)	NC score	0.183153 (rank : 211)
Query Neighborhood Hits	451	Target Neighborhood Hits	470	Shared Neighborhood Hits	158
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

AN30A_HUMAN
θ value	1.81305 (rank : 311)	NC score	0.052266 (rank : 599)
Query Neighborhood Hits	451	Target Neighborhood Hits	1119	Shared Neighborhood Hits	179
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ARI2_HUMAN
θ value	1.81305 (rank : 312)	NC score	0.061918 (rank : 468)
Query Neighborhood Hits	451	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

BPAEA_HUMAN
θ value	1.81305 (rank : 313)	NC score	0.056502 (rank : 537)
Query Neighborhood Hits	451	Target Neighborhood Hits	1369	Shared Neighborhood Hits	203
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CASP_MOUSE
θ value	1.81305 (rank : 314)	NC score	0.073297 (rank : 359)
Query Neighborhood Hits	451	Target Neighborhood Hits	1152	Shared Neighborhood Hits	206
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CING_HUMAN
θ value	1.81305 (rank : 315)	NC score	0.069858 (rank : 389)
Query Neighborhood Hits	451	Target Neighborhood Hits	1275	Shared Neighborhood Hits	207
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

EXOC3_MOUSE
θ value	1.81305 (rank : 316)	NC score	0.021875 (rank : 679)
Query Neighborhood Hits	451	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

OPTN_MOUSE
θ value	1.81305 (rank : 317)	NC score	0.065304 (rank : 428)
Query Neighborhood Hits	451	Target Neighborhood Hits	1120	Shared Neighborhood Hits	188
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RNF32_HUMAN
θ value	1.81305 (rank : 318)	NC score	0.138366 (rank : 233)
Query Neighborhood Hits	451	Target Neighborhood Hits	133	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

TEX9_MOUSE
θ value	1.81305 (rank : 319)	NC score	0.058813 (rank : 508)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TRAF2_MOUSE
θ value	1.81305 (rank : 320)	NC score	0.194805 (rank : 203)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	133
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAIP_HUMAN
θ value	1.81305 (rank : 321)	NC score	0.178366 (rank : 216)
Query Neighborhood Hits	451	Target Neighborhood Hits	780	Shared Neighborhood Hits	207
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

ARI2_MOUSE
θ value	2.36792 (rank : 322)	NC score	0.059396 (rank : 500)
Query Neighborhood Hits	451	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

CCD45_MOUSE
θ value	2.36792 (rank : 323)	NC score	0.051500 (rank : 611)
Query Neighborhood Hits	451	Target Neighborhood Hits	663	Shared Neighborhood Hits	144
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CP250_MOUSE
θ value	2.36792 (rank : 324)	NC score	0.082228 (rank : 304)
Query Neighborhood Hits	451	Target Neighborhood Hits	1583	Shared Neighborhood Hits	240
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ENAH_HUMAN
θ value	2.36792 (rank : 325)	NC score	0.043421 (rank : 648)
Query Neighborhood Hits	451	Target Neighborhood Hits	784	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

GOGB1_HUMAN
θ value	2.36792 (rank : 326)	NC score	0.089413 (rank : 283)
Query Neighborhood Hits	451	Target Neighborhood Hits	2297	Shared Neighborhood Hits	278
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

INCE_MOUSE
θ value	2.36792 (rank : 327)	NC score	0.074091 (rank : 347)
Query Neighborhood Hits	451	Target Neighborhood Hits	903	Shared Neighborhood Hits	174
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

LIPA2_MOUSE
θ value	2.36792 (rank : 328)	NC score	0.060578 (rank : 488)
Query Neighborhood Hits	451	Target Neighborhood Hits	1282	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MKRN3_MOUSE
θ value	2.36792 (rank : 329)	NC score	0.062732 (rank : 460)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	57
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MYH13_HUMAN
θ value	2.36792 (rank : 330)	NC score	0.057622 (rank : 522)
Query Neighborhood Hits	451	Target Neighborhood Hits	1504	Shared Neighborhood Hits	224
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH8_MOUSE
θ value	2.36792 (rank : 331)	NC score	0.064613 (rank : 436)
Query Neighborhood Hits	451	Target Neighborhood Hits	1600	Shared Neighborhood Hits	234
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NOE1_HUMAN
θ value	2.36792 (rank : 332)	NC score	0.023336 (rank : 677)
Query Neighborhood Hits	451	Target Neighborhood Hits	266	Shared Neighborhood Hits	90
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

PEX2_MOUSE
θ value	2.36792 (rank : 333)	NC score	0.088327 (rank : 289)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

RNF34_HUMAN
θ value	2.36792 (rank : 334)	NC score	0.120404 (rank : 249)
Query Neighborhood Hits	451	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	2.36792 (rank : 335)	NC score	0.122805 (rank : 247)
Query Neighborhood Hits	451	Target Neighborhood Hits	160	Shared Neighborhood Hits	73
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

SDCG8_HUMAN
θ value	2.36792 (rank : 336)	NC score	0.079247 (rank : 321)
Query Neighborhood Hits	451	Target Neighborhood Hits	1002	Shared Neighborhood Hits	200
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

U2AFM_HUMAN
θ value	2.36792 (rank : 337)	NC score	0.044920 (rank : 646)
Query Neighborhood Hits	451	Target Neighborhood Hits	577	Shared Neighborhood Hits	138
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CD2L1_MOUSE
θ value	3.0926 (rank : 338)	NC score	0.003341 (rank : 710)
Query Neighborhood Hits	451	Target Neighborhood Hits	1463	Shared Neighborhood Hits	124
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DYHC_HUMAN
θ value	3.0926 (rank : 339)	NC score	0.034372 (rank : 660)
Query Neighborhood Hits	451	Target Neighborhood Hits	733	Shared Neighborhood Hits	153
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	3.0926 (rank : 340)	NC score	0.034246 (rank : 661)
Query Neighborhood Hits	451	Target Neighborhood Hits	729	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

EXOC3_HUMAN
θ value	3.0926 (rank : 341)	NC score	0.019504 (rank : 685)
Query Neighborhood Hits	451	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

GCC1_MOUSE
θ value	3.0926 (rank : 342)	NC score	0.083829 (rank : 299)
Query Neighborhood Hits	451	Target Neighborhood Hits	777	Shared Neighborhood Hits	177
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

IF4G3_HUMAN
θ value	3.0926 (rank : 343)	NC score	0.013387 (rank : 694)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
θ value	3.0926 (rank : 344)	NC score	0.010224 (rank : 703)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	36
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

KIF4A_HUMAN
θ value	3.0926 (rank : 345)	NC score	0.047491 (rank : 639)
Query Neighborhood Hits	451	Target Neighborhood Hits	1159	Shared Neighborhood Hits	199
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MNAB_HUMAN
θ value	3.0926 (rank : 346)	NC score	0.162805 (rank : 225)
Query Neighborhood Hits	451	Target Neighborhood Hits	196	Shared Neighborhood Hits	113
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	3.0926 (rank : 347)	NC score	0.160649 (rank : 229)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	111
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MY18A_HUMAN
θ value	3.0926 (rank : 348)	NC score	0.074970 (rank : 340)
Query Neighborhood Hits	451	Target Neighborhood Hits	1929	Shared Neighborhood Hits	244
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH10_MOUSE
θ value	3.0926 (rank : 349)	NC score	0.069604 (rank : 390)
Query Neighborhood Hits	451	Target Neighborhood Hits	1612	Shared Neighborhood Hits	240
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NOE1_MOUSE
θ value	3.0926 (rank : 350)	NC score	0.023781 (rank : 676)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	93
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

PHLB2_HUMAN
θ value	3.0926 (rank : 351)	NC score	0.071653 (rank : 373)
Query Neighborhood Hits	451	Target Neighborhood Hits	964	Shared Neighborhood Hits	182
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RIMB1_MOUSE
θ value	3.0926 (rank : 352)	NC score	0.057491 (rank : 525)
Query Neighborhood Hits	451	Target Neighborhood Hits	1376	Shared Neighborhood Hits	187
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RN183_MOUSE
θ value	3.0926 (rank : 353)	NC score	0.319798 (rank : 156)
Query Neighborhood Hits	451	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

ROCK2_MOUSE
θ value	3.0926 (rank : 354)	NC score	0.026904 (rank : 669)
Query Neighborhood Hits	451	Target Neighborhood Hits	2072	Shared Neighborhood Hits	218
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SEPT7_HUMAN
θ value	3.0926 (rank : 355)	NC score	0.020300 (rank : 682)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	109
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT7_MOUSE
θ value	3.0926 (rank : 356)	NC score	0.018429 (rank : 688)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	95
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SRBP1_MOUSE
θ value	3.0926 (rank : 357)	NC score	0.004004 (rank : 709)
Query Neighborhood Hits	451	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TACC1_HUMAN
θ value	3.0926 (rank : 358)	NC score	0.051075 (rank : 617)
Query Neighborhood Hits	451	Target Neighborhood Hits	597	Shared Neighborhood Hits	138
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TRAF2_HUMAN
θ value	3.0926 (rank : 359)	NC score	0.189435 (rank : 208)
Query Neighborhood Hits	451	Target Neighborhood Hits	402	Shared Neighborhood Hits	136
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

ARHGC_HUMAN
θ value	4.03905 (rank : 360)	NC score	0.010360 (rank : 702)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CALD1_HUMAN
θ value	4.03905 (rank : 361)	NC score	0.067503 (rank : 409)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	173
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCD46_MOUSE
θ value	4.03905 (rank : 362)	NC score	0.086046 (rank : 294)
Query Neighborhood Hits	451	Target Neighborhood Hits	1405	Shared Neighborhood Hits	229
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CING_MOUSE
θ value	4.03905 (rank : 363)	NC score	0.075809 (rank : 337)
Query Neighborhood Hits	451	Target Neighborhood Hits	1432	Shared Neighborhood Hits	220
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CTGE5_HUMAN
θ value	4.03905 (rank : 364)	NC score	0.058912 (rank : 505)
Query Neighborhood Hits	451	Target Neighborhood Hits	800	Shared Neighborhood Hits	171
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

FES_HUMAN
θ value	4.03905 (rank : 365)	NC score	-0.004922 (rank : 719)
Query Neighborhood Hits	451	Target Neighborhood Hits	978	Shared Neighborhood Hits	50
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

HIP1R_HUMAN
θ value	4.03905 (rank : 366)	NC score	0.058633 (rank : 510)
Query Neighborhood Hits	451	Target Neighborhood Hits	809	Shared Neighborhood Hits	175
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

MYH10_HUMAN
θ value	4.03905 (rank : 367)	NC score	0.068963 (rank : 394)
Query Neighborhood Hits	451	Target Neighborhood Hits	1620	Shared Neighborhood Hits	244
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NEK11_HUMAN
θ value	4.03905 (rank : 368)	NC score	-0.003916 (rank : 718)
Query Neighborhood Hits	451	Target Neighborhood Hits	1043	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

TACC2_MOUSE
θ value	4.03905 (rank : 369)	NC score	0.049704 (rank : 635)
Query Neighborhood Hits	451	Target Neighborhood Hits	774	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

VIME_HUMAN
θ value	4.03905 (rank : 370)	NC score	0.026103 (rank : 672)
Query Neighborhood Hits	451	Target Neighborhood Hits	706	Shared Neighborhood Hits	161
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

VIME_MOUSE
θ value	4.03905 (rank : 371)	NC score	0.027433 (rank : 667)
Query Neighborhood Hits	451	Target Neighborhood Hits	716	Shared Neighborhood Hits	161
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

ZSWM2_HUMAN
θ value	4.03905 (rank : 372)	NC score	0.092723 (rank : 275)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

BPA1_MOUSE
θ value	5.27518 (rank : 373)	NC score	0.051782 (rank : 607)
Query Neighborhood Hits	451	Target Neighborhood Hits	1477	Shared Neighborhood Hits	202
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	5.27518 (rank : 374)	NC score	0.069404 (rank : 392)
Query Neighborhood Hits	451	Target Neighborhood Hits	1480	Shared Neighborhood Hits	218
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CD2L1_HUMAN
θ value	5.27518 (rank : 375)	NC score	0.003323 (rank : 711)
Query Neighborhood Hits	451	Target Neighborhood Hits	1467	Shared Neighborhood Hits	128
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L2_HUMAN
θ value	5.27518 (rank : 376)	NC score	0.002214 (rank : 713)
Query Neighborhood Hits	451	Target Neighborhood Hits	1439	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CTTB2_HUMAN
θ value	5.27518 (rank : 377)	NC score	0.053958 (rank : 566)
Query Neighborhood Hits	451	Target Neighborhood Hits	1061	Shared Neighborhood Hits	186
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

CYLN2_MOUSE
θ value	5.27518 (rank : 378)	NC score	0.067760 (rank : 405)
Query Neighborhood Hits	451	Target Neighborhood Hits	1002	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

GCC2_MOUSE
θ value	5.27518 (rank : 379)	NC score	0.085999 (rank : 295)
Query Neighborhood Hits	451	Target Neighborhood Hits	1619	Shared Neighborhood Hits	246
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KI20A_HUMAN
θ value	5.27518 (rank : 380)	NC score	0.025204 (rank : 675)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	91
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

KIFC1_HUMAN
θ value	5.27518 (rank : 381)	NC score	0.034379 (rank : 659)
Query Neighborhood Hits	451	Target Neighborhood Hits	545	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

MACF1_HUMAN
θ value	5.27518 (rank : 382)	NC score	0.053617 (rank : 570)
Query Neighborhood Hits	451	Target Neighborhood Hits	1341	Shared Neighborhood Hits	196
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	5.27518 (rank : 383)	NC score	0.050299 (rank : 627)
Query Neighborhood Hits	451	Target Neighborhood Hits	1321	Shared Neighborhood Hits	194
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MKRN3_HUMAN
θ value	5.27518 (rank : 384)	NC score	0.076030 (rank : 336)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	74
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN4_HUMAN
θ value	5.27518 (rank : 385)	NC score	0.088617 (rank : 287)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	83
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MLL4_HUMAN
θ value	5.27518 (rank : 386)	NC score	0.004966 (rank : 708)
Query Neighborhood Hits	451	Target Neighborhood Hits	722	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MOES_HUMAN
θ value	5.27518 (rank : 387)	NC score	0.041703 (rank : 650)
Query Neighborhood Hits	451	Target Neighborhood Hits	892	Shared Neighborhood Hits	176
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MY18A_MOUSE
θ value	5.27518 (rank : 388)	NC score	0.070503 (rank : 379)
Query Neighborhood Hits	451	Target Neighborhood Hits	1989	Shared Neighborhood Hits	232
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH4_HUMAN
θ value	5.27518 (rank : 389)	NC score	0.059840 (rank : 494)
Query Neighborhood Hits	451	Target Neighborhood Hits	1377	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH8_HUMAN
θ value	5.27518 (rank : 390)	NC score	0.064534 (rank : 438)
Query Neighborhood Hits	451	Target Neighborhood Hits	1610	Shared Neighborhood Hits	229
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PEX2_HUMAN
θ value	5.27518 (rank : 391)	NC score	0.060303 (rank : 491)
Query Neighborhood Hits	451	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PHLB2_MOUSE
θ value	5.27518 (rank : 392)	NC score	0.073398 (rank : 356)
Query Neighborhood Hits	451	Target Neighborhood Hits	1016	Shared Neighborhood Hits	187
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLEC1_HUMAN
θ value	5.27518 (rank : 393)	NC score	0.064090 (rank : 442)
Query Neighborhood Hits	451	Target Neighborhood Hits	1326	Shared Neighborhood Hits	210
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SPRY4_HUMAN
θ value	5.27518 (rank : 394)	NC score	0.581214 (rank : 102)
Query Neighborhood Hits	451	Target Neighborhood Hits	79	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SYCP3_MOUSE
θ value	5.27518 (rank : 395)	NC score	0.027199 (rank : 668)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	61
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

UTRO_HUMAN
θ value	5.27518 (rank : 396)	NC score	0.040682 (rank : 651)
Query Neighborhood Hits	451	Target Neighborhood Hits	960	Shared Neighborhood Hits	171
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

ZN318_HUMAN
θ value	5.27518 (rank : 397)	NC score	0.022790 (rank : 678)
Query Neighborhood Hits	451	Target Neighborhood Hits	497	Shared Neighborhood Hits	92
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ARHGC_MOUSE
θ value	6.88961 (rank : 398)	NC score	0.009192 (rank : 705)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

AZI1_MOUSE
θ value	6.88961 (rank : 399)	NC score	0.083205 (rank : 301)
Query Neighborhood Hits	451	Target Neighborhood Hits	990	Shared Neighborhood Hits	191
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CAF1A_HUMAN
θ value	6.88961 (rank : 400)	NC score	0.053148 (rank : 581)
Query Neighborhood Hits	451	Target Neighborhood Hits	750	Shared Neighborhood Hits	148
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CE290_HUMAN
θ value	6.88961 (rank : 401)	NC score	0.081257 (rank : 311)
Query Neighborhood Hits	451	Target Neighborhood Hits	1553	Shared Neighborhood Hits	242
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP63_HUMAN
θ value	6.88961 (rank : 402)	NC score	0.071361 (rank : 375)
Query Neighborhood Hits	451	Target Neighborhood Hits	1005	Shared Neighborhood Hits	200
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

GCC2_HUMAN
θ value	6.88961 (rank : 403)	NC score	0.082051 (rank : 306)
Query Neighborhood Hits	451	Target Neighborhood Hits	1558	Shared Neighborhood Hits	246
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GIMA4_HUMAN
θ value	6.88961 (rank : 404)	NC score	0.019575 (rank : 683)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

HMMR_HUMAN
θ value	6.88961 (rank : 405)	NC score	0.071511 (rank : 374)
Query Neighborhood Hits	451	Target Neighborhood Hits	1082	Shared Neighborhood Hits	194
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

ITSN2_MOUSE
θ value	6.88961 (rank : 406)	NC score	0.046699 (rank : 641)
Query Neighborhood Hits	451	Target Neighborhood Hits	1371	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

M4K1_MOUSE
θ value	6.88961 (rank : 407)	NC score	-0.003629 (rank : 717)
Query Neighborhood Hits	451	Target Neighborhood Hits	858	Shared Neighborhood Hits	19
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

MACF1_MOUSE
θ value	6.88961 (rank : 408)	NC score	0.053079 (rank : 583)
Query Neighborhood Hits	451	Target Neighborhood Hits	1313	Shared Neighborhood Hits	198
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MKL1_HUMAN
θ value	6.88961 (rank : 409)	NC score	0.005803 (rank : 707)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	28
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MTSS1_HUMAN
θ value	6.88961 (rank : 410)	NC score	0.009819 (rank : 704)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	51
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MYH1_HUMAN
θ value	6.88961 (rank : 411)	NC score	0.061592 (rank : 472)
Query Neighborhood Hits	451	Target Neighborhood Hits	1478	Shared Neighborhood Hits	225
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

NIN_HUMAN
θ value	6.88961 (rank : 412)	NC score	0.086724 (rank : 293)
Query Neighborhood Hits	451	Target Neighborhood Hits	1416	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PHLB1_MOUSE
θ value	6.88961 (rank : 413)	NC score	0.037749 (rank : 654)
Query Neighborhood Hits	451	Target Neighborhood Hits	678	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PJA1_HUMAN
θ value	6.88961 (rank : 414)	NC score	0.103021 (rank : 259)
Query Neighborhood Hits	451	Target Neighborhood Hits	159	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RBP24_HUMAN
θ value	6.88961 (rank : 415)	NC score	0.082132 (rank : 305)
Query Neighborhood Hits	451	Target Neighborhood Hits	1559	Shared Neighborhood Hits	246
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RNF32_MOUSE
θ value	6.88961 (rank : 416)	NC score	0.121511 (rank : 248)
Query Neighborhood Hits	451	Target Neighborhood Hits	129	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

SYNE2_HUMAN
θ value	6.88961 (rank : 417)	NC score	0.056988 (rank : 533)
Query Neighborhood Hits	451	Target Neighborhood Hits	1323	Shared Neighborhood Hits	203
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TACC2_HUMAN
θ value	6.88961 (rank : 418)	NC score	0.054589 (rank : 561)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	157
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TAOK3_HUMAN
θ value	6.88961 (rank : 419)	NC score	0.011639 (rank : 699)
Query Neighborhood Hits	451	Target Neighborhood Hits	1494	Shared Neighborhood Hits	162
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

BIRC2_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.098693 (rank : 264)
Query Neighborhood Hits	451	Target Neighborhood Hits	142	Shared Neighborhood Hits	75
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BRE1B_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.128237 (rank : 241)
Query Neighborhood Hits	451	Target Neighborhood Hits	1040	Shared Neighborhood Hits	291
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	8.99809 (rank : 422)	NC score	0.129142 (rank : 239)
Query Neighborhood Hits	451	Target Neighborhood Hits	970	Shared Neighborhood Hits	287
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CCD21_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.058716 (rank : 509)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	190
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CNTRB_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.072072 (rank : 371)
Query Neighborhood Hits	451	Target Neighborhood Hits	1029	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CS029_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.026739 (rank : 670)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

EEA1_HUMAN
θ value	8.99809 (rank : 426)	NC score	0.077617 (rank : 330)
Query Neighborhood Hits	451	Target Neighborhood Hits	1796	Shared Neighborhood Hits	256
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ERCC5_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.012336 (rank : 696)
Query Neighborhood Hits	451	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

EVPL_MOUSE
θ value	8.99809 (rank : 428)	NC score	0.063023 (rank : 459)
Query Neighborhood Hits	451	Target Neighborhood Hits	952	Shared Neighborhood Hits	181
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FA76A_MOUSE
θ value	8.99809 (rank : 429)	NC score	0.011418 (rank : 701)
Query Neighborhood Hits	451	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

GAS8_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.059443 (rank : 499)
Query Neighborhood Hits	451	Target Neighborhood Hits	819	Shared Neighborhood Hits	182
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GOGA1_MOUSE
θ value	8.99809 (rank : 431)	NC score	0.065893 (rank : 425)
Query Neighborhood Hits	451	Target Neighborhood Hits	994	Shared Neighborhood Hits	181
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

IF2P_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.055809 (rank : 548)
Query Neighborhood Hits	451	Target Neighborhood Hits	889	Shared Neighborhood Hits	145
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

ITSN2_HUMAN
θ value	8.99809 (rank : 433)	NC score	0.038260 (rank : 652)
Query Neighborhood Hits	451	Target Neighborhood Hits	1173	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

K0555_HUMAN
θ value	8.99809 (rank : 434)	NC score	0.063340 (rank : 448)
Query Neighborhood Hits	451	Target Neighborhood Hits	880	Shared Neighborhood Hits	170
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

K1C12_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.017922 (rank : 690)
Query Neighborhood Hits	451	Target Neighborhood Hits	372	Shared Neighborhood Hits	107
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

MOES_MOUSE
θ value	8.99809 (rank : 436)	NC score	0.042338 (rank : 649)
Query Neighborhood Hits	451	Target Neighborhood Hits	923	Shared Neighborhood Hits	176
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MORC3_HUMAN
θ value	8.99809 (rank : 437)	NC score	0.035353 (rank : 658)
Query Neighborhood Hits	451	Target Neighborhood Hits	489	Shared Neighborhood Hits	118
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

MYH1_MOUSE
θ value	8.99809 (rank : 438)	NC score	0.060809 (rank : 485)
Query Neighborhood Hits	451	Target Neighborhood Hits	1461	Shared Neighborhood Hits	222
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	8.99809 (rank : 439)	NC score	0.061195 (rank : 478)
Query Neighborhood Hits	451	Target Neighborhood Hits	1491	Shared Neighborhood Hits	224
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

NHLC1_MOUSE
θ value	8.99809 (rank : 440)	NC score	0.182900 (rank : 212)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NPHP3_HUMAN
θ value	8.99809 (rank : 441)	NC score	0.012105 (rank : 697)
Query Neighborhood Hits	451	Target Neighborhood Hits	304	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

PCGF2_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.199640 (rank : 201)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	112
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	8.99809 (rank : 443)	NC score	0.199656 (rank : 200)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	111
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PEPL_MOUSE
θ value	8.99809 (rank : 444)	NC score	0.060586 (rank : 487)
Query Neighborhood Hits	451	Target Neighborhood Hits	1105	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PJA1_MOUSE
θ value	8.99809 (rank : 445)	NC score	0.078163 (rank : 327)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

SC15B_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.008017 (rank : 706)
Query Neighborhood Hits	451	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2D4	Gene names	SEC15L2, KIAA0919, SEC15B
Domain Architecture
Description	Exocyst complex component Sec15B.

SDCG8_MOUSE
θ value	8.99809 (rank : 447)	NC score	0.077008 (rank : 334)
Query Neighborhood Hits	451	Target Neighborhood Hits	886	Shared Neighborhood Hits	186
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SH21B_HUMAN
θ value	8.99809 (rank : 448)	NC score	-0.000007 (rank : 714)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SLK_MOUSE
θ value	8.99809 (rank : 449)	NC score	0.018623 (rank : 687)
Query Neighborhood Hits	451	Target Neighborhood Hits	1798	Shared Neighborhood Hits	194
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SMC2_MOUSE
θ value	8.99809 (rank : 450)	NC score	0.063064 (rank : 457)
Query Neighborhood Hits	451	Target Neighborhood Hits	1131	Shared Neighborhood Hits	197
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

UBP8_MOUSE
θ value	8.99809 (rank : 451)	NC score	0.002217 (rank : 712)
Query Neighborhood Hits	451	Target Neighborhood Hits	362	Shared Neighborhood Hits	48
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

ADIP_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.051474 (rank : 613)
Query Neighborhood Hits	451	Target Neighborhood Hits	470	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

AKAP9_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.077289 (rank : 333)
Query Neighborhood Hits	451	Target Neighborhood Hits	1710	Shared Neighborhood Hits	227
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

AL2SB_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.050150 (rank : 631)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	106
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

AMFR2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.173684 (rank : 220)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.173500 (rank : 221)
Query Neighborhood Hits	451	Target Neighborhood Hits	208	Shared Neighborhood Hits	120
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMOL2_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.051538 (rank : 609)
Query Neighborhood Hits	451	Target Neighborhood Hits	603	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.057720 (rank : 519)
Query Neighborhood Hits	451	Target Neighborhood Hits	591	Shared Neighborhood Hits	150
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AZI1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.080305 (rank : 315)
Query Neighborhood Hits	451	Target Neighborhood Hits	1000	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BICD1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.056659 (rank : 536)
Query Neighborhood Hits	451	Target Neighborhood Hits	844	Shared Neighborhood Hits	177
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.062315 (rank : 462)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	188
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.062062 (rank : 466)
Query Neighborhood Hits	451	Target Neighborhood Hits	864	Shared Neighborhood Hits	188
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIRC2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.092974 (rank : 274)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.098719 (rank : 263)
Query Neighborhood Hits	451	Target Neighborhood Hits	133	Shared Neighborhood Hits	69
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.075448 (rank : 338)
Query Neighborhood Hits	451	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC8_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.119750 (rank : 250)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BRE1A_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.113925 (rank : 252)
Query Neighborhood Hits	451	Target Neighborhood Hits	1071	Shared Neighborhood Hits	275
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.112531 (rank : 253)
Query Neighborhood Hits	451	Target Neighborhood Hits	1025	Shared Neighborhood Hits	269
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BT3A2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.198551 (rank : 202)
Query Neighborhood Hits	451	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTNL1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.191402 (rank : 204)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTNL2_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.184384 (rank : 209)
Query Neighborhood Hits	451	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

C102B_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.056125 (rank : 544)
Query Neighborhood Hits	451	Target Neighborhood Hits	542	Shared Neighborhood Hits	137
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CA065_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.054780 (rank : 559)
Query Neighborhood Hits	451	Target Neighborhood Hits	469	Shared Neighborhood Hits	129
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CAF1A_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.066583 (rank : 414)
Query Neighborhood Hits	451	Target Neighborhood Hits	736	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CARD9_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.054923 (rank : 558)
Query Neighborhood Hits	451	Target Neighborhood Hits	602	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASP_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.072795 (rank : 365)
Query Neighborhood Hits	451	Target Neighborhood Hits	1131	Shared Neighborhood Hits	206
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CBLB_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.127586 (rank : 242)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	130
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.128776 (rank : 240)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	132
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.124887 (rank : 246)
Query Neighborhood Hits	451	Target Neighborhood Hits	173	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.127521 (rank : 243)
Query Neighborhood Hits	451	Target Neighborhood Hits	186	Shared Neighborhood Hits	119
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.133104 (rank : 236)
Query Neighborhood Hits	451	Target Neighborhood Hits	353	Shared Neighborhood Hits	135
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.130743 (rank : 238)
Query Neighborhood Hits	451	Target Neighborhood Hits	426	Shared Neighborhood Hits	145
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CCD11_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.063257 (rank : 452)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	135
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.052975 (rank : 586)
Query Neighborhood Hits	451	Target Neighborhood Hits	721	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD21_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.057923 (rank : 516)
Query Neighborhood Hits	451	Target Neighborhood Hits	1228	Shared Neighborhood Hits	201
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.066384 (rank : 417)
Query Neighborhood Hits	451	Target Neighborhood Hits	594	Shared Neighborhood Hits	151
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD39_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.061330 (rank : 475)
Query Neighborhood Hits	451	Target Neighborhood Hits	868	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.060915 (rank : 482)
Query Neighborhood Hits	451	Target Neighborhood Hits	1026	Shared Neighborhood Hits	190
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD45_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.053443 (rank : 577)
Query Neighborhood Hits	451	Target Neighborhood Hits	525	Shared Neighborhood Hits	131
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD62_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.052926 (rank : 588)
Query Neighborhood Hits	451	Target Neighborhood Hits	631	Shared Neighborhood Hits	150
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.059029 (rank : 504)
Query Neighborhood Hits	451	Target Neighborhood Hits	699	Shared Neighborhood Hits	155
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD96_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.058434 (rank : 511)
Query Neighborhood Hits	451	Target Neighborhood Hits	704	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.053516 (rank : 573)
Query Neighborhood Hits	451	Target Neighborhood Hits	723	Shared Neighborhood Hits	161
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.060022 (rank : 493)
Query Neighborhood Hits	451	Target Neighborhood Hits	717	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.057777 (rank : 518)
Query Neighborhood Hits	451	Target Neighborhood Hits	932	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CD276_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.092604 (rank : 277)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.103088 (rank : 258)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD86_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.078885 (rank : 323)
Query Neighborhood Hits	451	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

CD86_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.073768 (rank : 351)
Query Neighborhood Hits	451	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CENPJ_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.058842 (rank : 507)
Query Neighborhood Hits	451	Target Neighborhood Hits	721	Shared Neighborhood Hits	157
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CEP55_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.053805 (rank : 569)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	138
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.073419 (rank : 355)
Query Neighborhood Hits	451	Target Neighborhood Hits	693	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.050499 (rank : 624)
Query Neighborhood Hits	451	Target Neighborhood Hits	580	Shared Neighborhood Hits	153
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP70_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.050556 (rank : 623)
Query Neighborhood Hits	451	Target Neighborhood Hits	532	Shared Neighborhood Hits	140
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CF060_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.083466 (rank : 300)
Query Neighborhood Hits	451	Target Neighborhood Hits	1270	Shared Neighborhood Hits	234
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF152_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.056374 (rank : 540)
Query Neighborhood Hits	451	Target Neighborhood Hits	597	Shared Neighborhood Hits	143
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CI039_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.064109 (rank : 440)
Query Neighborhood Hits	451	Target Neighborhood Hits	1171	Shared Neighborhood Hits	198
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.072148 (rank : 368)
Query Neighborhood Hits	451	Target Neighborhood Hits	1088	Shared Neighborhood Hits	202
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CJ118_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.059685 (rank : 498)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	180
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CJ118_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.062705 (rank : 461)
Query Neighborhood Hits	451	Target Neighborhood Hits	1132	Shared Neighborhood Hits	194
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.053560 (rank : 571)
Query Neighborhood Hits	451	Target Neighborhood Hits	1151	Shared Neighborhood Hits	182
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.050245 (rank : 629)
Query Neighborhood Hits	451	Target Neighborhood Hits	592	Shared Neighborhood Hits	134
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.051588 (rank : 608)
Query Neighborhood Hits	451	Target Neighborhood Hits	596	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CN145_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.070660 (rank : 378)
Query Neighborhood Hits	451	Target Neighborhood Hits	1196	Shared Neighborhood Hits	208
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CN145_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.073809 (rank : 350)
Query Neighborhood Hits	451	Target Neighborhood Hits	916	Shared Neighborhood Hits	192
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNTRB_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.070141 (rank : 383)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.061777 (rank : 470)
Query Neighborhood Hits	451	Target Neighborhood Hits	1290	Shared Neighborhood Hits	203
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.060035 (rank : 492)
Query Neighborhood Hits	451	Target Neighborhood Hits	1278	Shared Neighborhood Hits	211
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CR034_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.051117 (rank : 616)
Query Neighborhood Hits	451	Target Neighborhood Hits	538	Shared Neighborhood Hits	145
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CROCC_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.072966 (rank : 363)
Query Neighborhood Hits	451	Target Neighborhood Hits	1409	Shared Neighborhood Hits	221
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.073258 (rank : 361)
Query Neighborhood Hits	451	Target Neighborhood Hits	1460	Shared Neighborhood Hits	223
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT096_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.060851 (rank : 484)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT116_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.051900 (rank : 606)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	89
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CUTL1_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.066841 (rank : 412)
Query Neighborhood Hits	451	Target Neighborhood Hits	1574	Shared Neighborhood Hits	211
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CYLN2_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.063504 (rank : 446)
Query Neighborhood Hits	451	Target Neighborhood Hits	1004	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYTSA_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.067094 (rank : 410)
Query Neighborhood Hits	451	Target Neighborhood Hits	1138	Shared Neighborhood Hits	203
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.065347 (rank : 427)
Query Neighborhood Hits	451	Target Neighborhood Hits	1104	Shared Neighborhood Hits	205
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DZIP3_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.056284 (rank : 542)
Query Neighborhood Hits	451	Target Neighborhood Hits	399	Shared Neighborhood Hits	144
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.062013 (rank : 467)
Query Neighborhood Hits	451	Target Neighborhood Hits	414	Shared Neighborhood Hits	149
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

EEA1_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.068633 (rank : 397)
Query Neighborhood Hits	451	Target Neighborhood Hits	1637	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ERC2_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.057597 (rank : 524)
Query Neighborhood Hits	451	Target Neighborhood Hits	1156	Shared Neighborhood Hits	195
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.057430 (rank : 526)
Query Neighborhood Hits	451	Target Neighborhood Hits	1166	Shared Neighborhood Hits	195
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

EVPL_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.062212 (rank : 463)
Query Neighborhood Hits	451	Target Neighborhood Hits	895	Shared Neighborhood Hits	181
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

FLIP1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.077418 (rank : 332)
Query Neighborhood Hits	451	Target Neighborhood Hits	1405	Shared Neighborhood Hits	227
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.077598 (rank : 331)
Query Neighborhood Hits	451	Target Neighborhood Hits	1176	Shared Neighborhood Hits	206
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FSD1L_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.079524 (rank : 319)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.093962 (rank : 270)
Query Neighborhood Hits	451	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FYCO1_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.063211 (rank : 454)
Query Neighborhood Hits	451	Target Neighborhood Hits	1149	Shared Neighborhood Hits	194
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.057666 (rank : 520)
Query Neighborhood Hits	451	Target Neighborhood Hits	1059	Shared Neighborhood Hits	184
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GAS8_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.056829 (rank : 535)
Query Neighborhood Hits	451	Target Neighborhood Hits	622	Shared Neighborhood Hits	156
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCP60_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.052367 (rank : 596)
Query Neighborhood Hits	451	Target Neighborhood Hits	419	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GOG8A_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.053432 (rank : 578)
Query Neighborhood Hits	451	Target Neighborhood Hits	635	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.073701 (rank : 352)
Query Neighborhood Hits	451	Target Neighborhood Hits	1222	Shared Neighborhood Hits	204
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.059141 (rank : 502)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	166
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.063660 (rank : 445)
Query Neighborhood Hits	451	Target Neighborhood Hits	944	Shared Neighborhood Hits	185
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.070089 (rank : 386)
Query Neighborhood Hits	451	Target Neighborhood Hits	1317	Shared Neighborhood Hits	214
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.067883 (rank : 403)
Query Neighborhood Hits	451	Target Neighborhood Hits	1437	Shared Neighborhood Hits	226
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.066242 (rank : 421)
Query Neighborhood Hits	451	Target Neighborhood Hits	1434	Shared Neighborhood Hits	211
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.074455 (rank : 344)
Query Neighborhood Hits	451	Target Neighborhood Hits	1007	Shared Neighborhood Hits	197
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GRAP1_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.060411 (rank : 489)
Query Neighborhood Hits	451	Target Neighborhood Hits	944	Shared Neighborhood Hits	185
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.069280 (rank : 393)
Query Neighborhood Hits	451	Target Neighborhood Hits	1234	Shared Neighborhood Hits	208
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HAP1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.061499 (rank : 473)
Query Neighborhood Hits	451	Target Neighborhood Hits	606	Shared Neighborhood Hits	154
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HHLA2_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.079640 (rank : 318)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HIP1R_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.053019 (rank : 585)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	175
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.050949 (rank : 619)
Query Neighborhood Hits	451	Target Neighborhood Hits	1016	Shared Neighborhood Hits	182
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HOME2_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.056404 (rank : 539)
Query Neighborhood Hits	451	Target Neighborhood Hits	882	Shared Neighborhood Hits	179
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK1_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.057423 (rank : 527)
Query Neighborhood Hits	451	Target Neighborhood Hits	942	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.056282 (rank : 543)
Query Neighborhood Hits	451	Target Neighborhood Hits	910	Shared Neighborhood Hits	180
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.051348 (rank : 614)
Query Neighborhood Hits	451	Target Neighborhood Hits	714	Shared Neighborhood Hits	161
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK2_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.050284 (rank : 628)
Query Neighborhood Hits	451	Target Neighborhood Hits	736	Shared Neighborhood Hits	168
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

HOOK3_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.055735 (rank : 551)
Query Neighborhood Hits	451	Target Neighborhood Hits	1070	Shared Neighborhood Hits	194
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.054966 (rank : 556)
Query Neighborhood Hits	451	Target Neighborhood Hits	1007	Shared Neighborhood Hits	187
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

ICOSL_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.090855 (rank : 280)
Query Neighborhood Hits	451	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.073245 (rank : 362)
Query Neighborhood Hits	451	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

IF3A_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.063324 (rank : 450)
Query Neighborhood Hits	451	Target Neighborhood Hits	875	Shared Neighborhood Hits	179
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.063233 (rank : 453)
Query Neighborhood Hits	451	Target Neighborhood Hits	871	Shared Neighborhood Hits	176
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.061234 (rank : 477)
Query Neighborhood Hits	451	Target Neighborhood Hits	949	Shared Neighborhood Hits	179
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.063709 (rank : 444)
Query Neighborhood Hits	451	Target Neighborhood Hits	939	Shared Neighborhood Hits	192
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.066262 (rank : 420)
Query Neighborhood Hits	451	Target Neighborhood Hits	893	Shared Neighborhood Hits	189
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.058323 (rank : 513)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	185
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INVO_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.053929 (rank : 568)
Query Neighborhood Hits	451	Target Neighborhood Hits	636	Shared Neighborhood Hits	138
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

KMHN1_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.055494 (rank : 553)
Query Neighborhood Hits	451	Target Neighborhood Hits	950	Shared Neighborhood Hits	180
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.053961 (rank : 565)
Query Neighborhood Hits	451	Target Neighborhood Hits	949	Shared Neighborhood Hits	170
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KNTC2_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.053339 (rank : 579)
Query Neighborhood Hits	451	Target Neighborhood Hits	673	Shared Neighborhood Hits	160
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.052970 (rank : 587)
Query Neighborhood Hits	451	Target Neighborhood Hits	692	Shared Neighborhood Hits	162
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KTN1_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.070389 (rank : 381)
Query Neighborhood Hits	451	Target Neighborhood Hits	1197	Shared Neighborhood Hits	205
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LIPA1_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.059764 (rank : 496)
Query Neighborhood Hits	451	Target Neighborhood Hits	1294	Shared Neighborhood Hits	204
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPA2_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.059314 (rank : 501)
Query Neighborhood Hits	451	Target Neighborhood Hits	1044	Shared Neighborhood Hits	186
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA3_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.053953 (rank : 567)
Query Neighborhood Hits	451	Target Neighborhood Hits	828	Shared Neighborhood Hits	175
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRC45_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.061905 (rank : 469)
Query Neighborhood Hits	451	Target Neighborhood Hits	933	Shared Neighborhood Hits	180
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.065789 (rank : 426)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	177
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF2_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.051921 (rank : 605)
Query Neighborhood Hits	451	Target Neighborhood Hits	791	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRSM1_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.089333 (rank : 284)
Query Neighborhood Hits	451	Target Neighborhood Hits	1078	Shared Neighborhood Hits	222
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LUZP1_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.052429 (rank : 595)
Query Neighborhood Hits	451	Target Neighborhood Hits	940	Shared Neighborhood Hits	159
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MD1L1_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.065096 (rank : 430)
Query Neighborhood Hits	451	Target Neighborhood Hits	893	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.066028 (rank : 423)
Query Neighborhood Hits	451	Target Neighborhood Hits	1001	Shared Neighborhood Hits	193
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MGRN1_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.099109 (rank : 262)
Query Neighborhood Hits	451	Target Neighborhood Hits	192	Shared Neighborhood Hits	83
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.103219 (rank : 257)
Query Neighborhood Hits	451	Target Neighborhood Hits	149	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MKRN1_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.064986 (rank : 432)
Query Neighborhood Hits	451	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.064041 (rank : 443)
Query Neighborhood Hits	451	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN2_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.088368 (rank : 288)
Query Neighborhood Hits	451	Target Neighborhood Hits	129	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.088951 (rank : 285)
Query Neighborhood Hits	451	Target Neighborhood Hits	130	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MOG_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.179679 (rank : 214)
Query Neighborhood Hits	451	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.179045 (rank : 215)
Query Neighborhood Hits	451	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MY18B_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.053490 (rank : 575)
Query Neighborhood Hits	451	Target Neighborhood Hits	1299	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH14_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.055170 (rank : 555)
Query Neighborhood Hits	451	Target Neighborhood Hits	995	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.063037 (rank : 458)
Query Neighborhood Hits	451	Target Neighborhood Hits	1225	Shared Neighborhood Hits	213
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH3_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.061038 (rank : 480)
Query Neighborhood Hits	451	Target Neighborhood Hits	1660	Shared Neighborhood Hits	234
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.060728 (rank : 486)
Query Neighborhood Hits	451	Target Neighborhood Hits	1476	Shared Neighborhood Hits	227
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.057171 (rank : 531)
Query Neighborhood Hits	451	Target Neighborhood Hits	1426	Shared Neighborhood Hits	221
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.059776 (rank : 495)
Query Neighborhood Hits	451	Target Neighborhood Hits	1501	Shared Neighborhood Hits	226
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.057610 (rank : 523)
Query Neighborhood Hits	451	Target Neighborhood Hits	1559	Shared Neighborhood Hits	223
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYLIP_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.050169 (rank : 630)
Query Neighborhood Hits	451	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYO5C_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.058115 (rank : 514)
Query Neighborhood Hits	451	Target Neighborhood Hits	1206	Shared Neighborhood Hits	212
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NAF1_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.057631 (rank : 521)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	180
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.063066 (rank : 456)
Query Neighborhood Hits	451	Target Neighborhood Hits	852	Shared Neighborhood Hits	183
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NDE1_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.063413 (rank : 447)
Query Neighborhood Hits	451	Target Neighborhood Hits	823	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NEB2_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.052701 (rank : 590)
Query Neighborhood Hits	451	Target Neighborhood Hits	883	Shared Neighborhood Hits	174
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.053124 (rank : 582)
Query Neighborhood Hits	451	Target Neighborhood Hits	889	Shared Neighborhood Hits	173
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEMO_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.055788 (rank : 550)
Query Neighborhood Hits	451	Target Neighborhood Hits	820	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.061267 (rank : 476)
Query Neighborhood Hits	451	Target Neighborhood Hits	658	Shared Neighborhood Hits	165
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NEST_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.069972 (rank : 388)
Query Neighborhood Hits	451	Target Neighborhood Hits	1305	Shared Neighborhood Hits	180
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NEUL1_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.078613 (rank : 326)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.077911 (rank : 328)
Query Neighborhood Hits	451	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NHLC1_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.175609 (rank : 218)
Query Neighborhood Hits	451	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NIN_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.079810 (rank : 317)
Query Neighborhood Hits	451	Target Neighborhood Hits	1376	Shared Neighborhood Hits	216
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUF2_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.052041 (rank : 604)
Query Neighborhood Hits	451	Target Neighborhood Hits	661	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUF2_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.052436 (rank : 594)
Query Neighborhood Hits	451	Target Neighborhood Hits	585	Shared Neighborhood Hits	149
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

OFD1_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.058036 (rank : 515)
Query Neighborhood Hits	451	Target Neighborhood Hits	753	Shared Neighborhood Hits	167
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OPTN_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.050074 (rank : 634)
Query Neighborhood Hits	451	Target Neighborhood Hits	827	Shared Neighborhood Hits	159
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PDL1_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.063312 (rank : 451)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.082509 (rank : 302)
Query Neighborhood Hits	451	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.068860 (rank : 395)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.064823 (rank : 434)
Query Neighborhood Hits	451	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PEPL_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.066435 (rank : 416)
Query Neighborhood Hits	451	Target Neighborhood Hits	1141	Shared Neighborhood Hits	195
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PHLB3_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.050724 (rank : 620)
Query Neighborhood Hits	451	Target Neighborhood Hits	304	Shared Neighborhood Hits	99
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PIBF1_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.067534 (rank : 408)
Query Neighborhood Hits	451	Target Neighborhood Hits	1041	Shared Neighborhood Hits	195
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PML_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.272715 (rank : 172)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	119
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.244377 (rank : 184)
Query Neighborhood Hits	451	Target Neighborhood Hits	246	Shared Neighborhood Hits	134
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

R113A_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.225749 (rank : 189)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	132
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.242288 (rank : 185)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RABE1_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.074547 (rank : 342)
Query Neighborhood Hits	451	Target Neighborhood Hits	1104	Shared Neighborhood Hits	201
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.074520 (rank : 343)
Query Neighborhood Hits	451	Target Neighborhood Hits	1105	Shared Neighborhood Hits	204
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RABE2_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.054146 (rank : 564)
Query Neighborhood Hits	451	Target Neighborhood Hits	598	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.068350 (rank : 400)
Query Neighborhood Hits	451	Target Neighborhood Hits	1317	Shared Neighborhood Hits	211
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.066770 (rank : 413)
Query Neighborhood Hits	451	Target Neighborhood Hits	1366	Shared Neighborhood Hits	215
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAI14_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.051477 (rank : 612)
Query Neighborhood Hits	451	Target Neighborhood Hits	1505	Shared Neighborhood Hits	203
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RB6I2_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.066367 (rank : 418)
Query Neighborhood Hits	451	Target Neighborhood Hits	1584	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.064094 (rank : 441)
Query Neighborhood Hits	451	Target Neighborhood Hits	1433	Shared Neighborhood Hits	218
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.073260 (rank : 360)
Query Neighborhood Hits	451	Target Neighborhood Hits	1023	Shared Neighborhood Hits	203
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.073331 (rank : 358)
Query Neighborhood Hits	451	Target Neighborhood Hits	1048	Shared Neighborhood Hits	196
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

REST_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.074129 (rank : 346)
Query Neighborhood Hits	451	Target Neighborhood Hits	1605	Shared Neighborhood Hits	233
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.068220 (rank : 401)
Query Neighborhood Hits	451	Target Neighborhood Hits	1506	Shared Neighborhood Hits	220
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFFL_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.081335 (rank : 309)
Query Neighborhood Hits	451	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.078980 (rank : 322)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFIP3_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.066116 (rank : 422)
Query Neighborhood Hits	451	Target Neighborhood Hits	1055	Shared Neighborhood Hits	183
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.059730 (rank : 497)
Query Neighborhood Hits	451	Target Neighborhood Hits	785	Shared Neighborhood Hits	171
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.060897 (rank : 483)
Query Neighborhood Hits	451	Target Neighborhood Hits	708	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RKHD1_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.110144 (rank : 256)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN122_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.067766 (rank : 404)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.061123 (rank : 479)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN123_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.102088 (rank : 261)
Query Neighborhood Hits	451	Target Neighborhood Hits	175	Shared Neighborhood Hits	107
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.102257 (rank : 260)
Query Neighborhood Hits	451	Target Neighborhood Hits	174	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN126_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.058375 (rank : 512)
Query Neighborhood Hits	451	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.066485 (rank : 415)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN152_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.166461 (rank : 224)
Query Neighborhood Hits	451	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.170643 (rank : 223)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN165_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.056995 (rank : 532)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN167_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.057348 (rank : 528)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.062209 (rank : 464)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.052236 (rank : 601)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	56
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.050700 (rank : 621)
Query Neighborhood Hits	451	Target Neighborhood Hits	164	Shared Neighborhood Hits	65
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF17_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.056045 (rank : 545)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RNF19_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.064902 (rank : 433)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.065189 (rank : 429)
Query Neighborhood Hits	451	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF26_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.082304 (rank : 303)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RRBP1_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.054256 (rank : 563)
Query Neighborhood Hits	451	Target Neighborhood Hits	1306	Shared Neighborhood Hits	191
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRBP1_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.050361 (rank : 626)
Query Neighborhood Hits	451	Target Neighborhood Hits	1650	Shared Neighborhood Hits	204
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RUFY1_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.052488 (rank : 592)
Query Neighborhood Hits	451	Target Neighborhood Hits	848	Shared Neighborhood Hits	182
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.068809 (rank : 396)
Query Neighborhood Hits	451	Target Neighborhood Hits	1208	Shared Neighborhood Hits	192
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.050364 (rank : 625)
Query Neighborhood Hits	451	Target Neighborhood Hits	820	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SAS6_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.052483 (rank : 593)
Query Neighborhood Hits	451	Target Neighborhood Hits	791	Shared Neighborhood Hits	166
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SAS6_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.057340 (rank : 529)
Query Neighborhood Hits	451	Target Neighborhood Hits	931	Shared Neighborhood Hits	174
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SIAH2_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.067750 (rank : 406)
Query Neighborhood Hits	451	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.067557 (rank : 407)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	55
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SM1L2_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.065960 (rank : 424)
Query Neighborhood Hits	451	Target Neighborhood Hits	1019	Shared Neighborhood Hits	191
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SM1L2_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.063328 (rank : 449)
Query Neighborhood Hits	451	Target Neighborhood Hits	918	Shared Neighborhood Hits	191
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMC3_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.064593 (rank : 437)
Query Neighborhood Hits	451	Target Neighborhood Hits	1186	Shared Neighborhood Hits	198
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.064494 (rank : 439)
Query Neighborhood Hits	451	Target Neighborhood Hits	1187	Shared Neighborhood Hits	198
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC4_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.054946 (rank : 557)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.055969 (rank : 546)
Query Neighborhood Hits	451	Target Neighborhood Hits	830	Shared Neighborhood Hits	168
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SPAG5_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.057228 (rank : 530)
Query Neighborhood Hits	451	Target Neighborhood Hits	625	Shared Neighborhood Hits	158
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SPAG5_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.059106 (rank : 503)
Query Neighborhood Hits	451	Target Neighborhood Hits	612	Shared Neighborhood Hits	149
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

STXB4_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.055345 (rank : 554)
Query Neighborhood Hits	451	Target Neighborhood Hits	616	Shared Neighborhood Hits	141
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SWP70_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.061752 (rank : 471)
Query Neighborhood Hits	451	Target Neighborhood Hits	973	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.070093 (rank : 385)
Query Neighborhood Hits	451	Target Neighborhood Hits	1097	Shared Neighborhood Hits	204
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYCP1_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.070473 (rank : 380)
Query Neighborhood Hits	451	Target Neighborhood Hits	1313	Shared Neighborhood Hits	208
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE1_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.063152 (rank : 455)
Query Neighborhood Hits	451	Target Neighborhood Hits	1484	Shared Neighborhood Hits	219
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TACC3_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.050115 (rank : 632)
Query Neighborhood Hits	451	Target Neighborhood Hits	607	Shared Neighborhood Hits	140
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TAXB1_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.053521 (rank : 572)
Query Neighborhood Hits	451	Target Neighborhood Hits	829	Shared Neighborhood Hits	165
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.052355 (rank : 597)
Query Neighborhood Hits	451	Target Neighborhood Hits	886	Shared Neighborhood Hits	166
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TEX9_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.050645 (rank : 622)
Query Neighborhood Hits	451	Target Neighborhood Hits	541	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TMF1_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.065052 (rank : 431)
Query Neighborhood Hits	451	Target Neighborhood Hits	987	Shared Neighborhood Hits	185
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNIP3_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.055822 (rank : 547)
Query Neighborhood Hits	451	Target Neighborhood Hits	511	Shared Neighborhood Hits	140
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TPM1_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.050078 (rank : 633)
Query Neighborhood Hits	451	Target Neighborhood Hits	716	Shared Neighborhood Hits	162
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.051225 (rank : 615)
Query Neighborhood Hits	451	Target Neighborhood Hits	729	Shared Neighborhood Hits	163
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM2_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.054355 (rank : 562)
Query Neighborhood Hits	451	Target Neighborhood Hits	677	Shared Neighborhood Hits	152
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.053065 (rank : 584)
Query Neighborhood Hits	451	Target Neighborhood Hits	676	Shared Neighborhood Hits	153
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM3_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.052646 (rank : 591)
Query Neighborhood Hits	451	Target Neighborhood Hits	689	Shared Neighborhood Hits	154
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.053202 (rank : 580)
Query Neighborhood Hits	451	Target Neighborhood Hits	676	Shared Neighborhood Hits	152
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM4_MOUSE
θ value	θ > 10 (rank : 701)	NC score	0.055511 (rank : 552)
Query Neighborhood Hits	451	Target Neighborhood Hits	703	Shared Neighborhood Hits	166
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPR_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.078646 (rank : 325)
Query Neighborhood Hits	451	Target Neighborhood Hits	1921	Shared Neighborhood Hits	244
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAF4_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.133839 (rank : 235)
Query Neighborhood Hits	451	Target Neighborhood Hits	338	Shared Neighborhood Hits	106
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAIP_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.162289 (rank : 227)
Query Neighborhood Hits	451	Target Neighborhood Hits	745	Shared Neighborhood Hits	209
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI66_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.092665 (rank : 276)
Query Neighborhood Hits	451	Target Neighborhood Hits	479	Shared Neighborhood Hits	95
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.096438 (rank : 265)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	98
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRIPB_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.077883 (rank : 329)
Query Neighborhood Hits	451	Target Neighborhood Hits	1587	Shared Neighborhood Hits	233
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TSC1_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.053495 (rank : 574)
Query Neighborhood Hits	451	Target Neighborhood Hits	765	Shared Neighborhood Hits	163
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TTC3_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.073988 (rank : 348)
Query Neighborhood Hits	451	Target Neighborhood Hits	664	Shared Neighborhood Hits	174
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TUFT1_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.052719 (rank : 589)
Query Neighborhood Hits	451	Target Neighborhood Hits	686	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.056832 (rank : 534)
Query Neighborhood Hits	451	Target Neighborhood Hits	732	Shared Neighborhood Hits	165
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UACA_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.072142 (rank : 369)
Query Neighborhood Hits	451	Target Neighborhood Hits	1622	Shared Neighborhood Hits	230
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UACA_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.056430 (rank : 538)
Query Neighborhood Hits	451	Target Neighborhood Hits	1620	Shared Neighborhood Hits	227
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

XE7_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.061023 (rank : 481)
Query Neighborhood Hits	451	Target Neighborhood Hits	738	Shared Neighborhood Hits	159
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ZC313_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.052260 (rank : 600)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	126
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN291_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.056309 (rank : 541)
Query Neighborhood Hits	451	Target Neighborhood Hits	647	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ZN364_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.066289 (rank : 419)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.058871 (rank : 506)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZSWM2_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.070239 (rank : 382)
Query Neighborhood Hits	451	Target Neighborhood Hits	132	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

TRIM6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	451	Target Neighborhood Hits	451	Shared Neighborhood Hits	451
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM6_HUMAN
NC score	0.985529 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	451	Target Neighborhood Hits	412	Shared Neighborhood Hits	309
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM5_HUMAN
NC score	0.978219 (rank : 3)	θ value	2.87295e-139 (rank : 5)
Query Neighborhood Hits	451	Target Neighborhood Hits	424	Shared Neighborhood Hits	282
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI22_HUMAN
NC score	0.975532 (rank : 4)	θ value	8.0776e-142 (rank : 4)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI34_HUMAN
NC score	0.971725 (rank : 5)	θ value	2.2711e-144 (rank : 3)
Query Neighborhood Hits	451	Target Neighborhood Hits	416	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
NC score	0.967882 (rank : 6)	θ value	1.25199e-126 (rank : 6)
Query Neighborhood Hits	451	Target Neighborhood Hits	332	Shared Neighborhood Hits	230
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI30_MOUSE
NC score	0.966322 (rank : 7)	θ value	1.13764e-111 (rank : 7)
Query Neighborhood Hits	451	Target Neighborhood Hits	434	Shared Neighborhood Hits	292
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

RO52_MOUSE
NC score	0.965508 (rank : 8)	θ value	4.20666e-90 (rank : 10)
Query Neighborhood Hits	451	Target Neighborhood Hits	360	Shared Neighborhood Hits	261
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RO52_HUMAN
NC score	0.964325 (rank : 9)	θ value	1.18001e-100 (rank : 8)
Query Neighborhood Hits	451	Target Neighborhood Hits	419	Shared Neighborhood Hits	285
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI68_HUMAN
NC score	0.962184 (rank : 10)	θ value	3.44127e-92 (rank : 9)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	226
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI38_HUMAN
NC score	0.959940 (rank : 11)	θ value	3.34088e-79 (rank : 12)
Query Neighborhood Hits	451	Target Neighborhood Hits	373	Shared Neighborhood Hits	266
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI68_MOUSE
NC score	0.959389 (rank : 12)	θ value	1.2666e-86 (rank : 11)
Query Neighborhood Hits	451	Target Neighborhood Hits	356	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI60_HUMAN
NC score	0.951680 (rank : 13)	θ value	2.10721e-57 (rank : 20)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	267
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI11_MOUSE
NC score	0.951185 (rank : 14)	θ value	6.11685e-65 (rank : 18)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	246
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.949528 (rank : 15)	θ value	1.07722e-69 (rank : 13)
Query Neighborhood Hits	451	Target Neighborhood Hits	316	Shared Neighborhood Hits	240
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRIM4_HUMAN
NC score	0.949108 (rank : 16)	θ value	1.51363e-47 (rank : 27)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	250
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI17_HUMAN
NC score	0.948482 (rank : 17)	θ value	4.25575e-50 (rank : 24)
Query Neighborhood Hits	451	Target Neighborhood Hits	318	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI27_HUMAN
NC score	0.947478 (rank : 18)	θ value	2.65329e-68 (rank : 14)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.946006 (rank : 19)	θ value	7.71989e-68 (rank : 16)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	205
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI43_HUMAN
NC score	0.944554 (rank : 20)	θ value	4.86918e-46 (rank : 28)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	258
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRIM7_MOUSE
NC score	0.942170 (rank : 21)	θ value	1.32293e-51 (rank : 22)
Query Neighborhood Hits	451	Target Neighborhood Hits	358	Shared Neighborhood Hits	262
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM7_HUMAN
NC score	0.941844 (rank : 22)	θ value	2.75849e-49 (rank : 25)
Query Neighborhood Hits	451	Target Neighborhood Hits	336	Shared Neighborhood Hits	257
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI10_HUMAN
NC score	0.941061 (rank : 23)	θ value	2.04573e-44 (rank : 31)
Query Neighborhood Hits	451	Target Neighborhood Hits	315	Shared Neighborhood Hits	246
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI60_MOUSE
NC score	0.940340 (rank : 24)	θ value	1.41672e-45 (rank : 29)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	197
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI10_MOUSE
NC score	0.936742 (rank : 25)	θ value	2.95404e-43 (rank : 33)
Query Neighborhood Hits	451	Target Neighborhood Hits	285	Shared Neighborhood Hits	229
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI39_MOUSE
NC score	0.936717 (rank : 26)	θ value	5.91091e-68 (rank : 15)
Query Neighborhood Hits	451	Target Neighborhood Hits	691	Shared Neighborhood Hits	340
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI17_MOUSE
NC score	0.935628 (rank : 27)	θ value	3.58603e-65 (rank : 17)
Query Neighborhood Hits	451	Target Neighborhood Hits	620	Shared Neighborhood Hits	322
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI39_HUMAN
NC score	0.935265 (rank : 28)	θ value	7.98882e-65 (rank : 19)
Query Neighborhood Hits	451	Target Neighborhood Hits	693	Shared Neighborhood Hits	342
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI41_HUMAN
NC score	0.930859 (rank : 29)	θ value	2.41655e-45 (rank : 30)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	241
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI49_HUMAN
NC score	0.929494 (rank : 30)	θ value	5.20228e-48 (rank : 26)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI26_HUMAN
NC score	0.926871 (rank : 31)	θ value	2.04573e-44 (rank : 32)
Query Neighborhood Hits	451	Target Neighborhood Hits	335	Shared Neighborhood Hits	242
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
NC score	0.924366 (rank : 32)	θ value	1.62093e-41 (rank : 34)
Query Neighborhood Hits	451	Target Neighborhood Hits	339	Shared Neighborhood Hits	249
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI50_MOUSE
NC score	0.918000 (rank : 33)	θ value	3.99248e-40 (rank : 36)
Query Neighborhood Hits	451	Target Neighborhood Hits	326	Shared Neighborhood Hits	239
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI15_HUMAN
NC score	0.917762 (rank : 34)	θ value	5.76516e-39 (rank : 37)
Query Neighborhood Hits	451	Target Neighborhood Hits	395	Shared Neighborhood Hits	272
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI62_MOUSE
NC score	0.914969 (rank : 35)	θ value	1.73584e-35 (rank : 40)
Query Neighborhood Hits	451	Target Neighborhood Hits	478	Shared Neighborhood Hits	278
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI50_HUMAN
NC score	0.913267 (rank : 36)	θ value	3.61106e-41 (rank : 35)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	231
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI12_MOUSE
NC score	0.910442 (rank : 37)	θ value	2.32979e-56 (rank : 21)
Query Neighborhood Hits	451	Target Neighborhood Hits	387	Shared Neighborhood Hits	255
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI62_HUMAN
NC score	0.909843 (rank : 38)	θ value	5.76516e-39 (rank : 38)
Query Neighborhood Hits	451	Target Neighborhood Hits	584	Shared Neighborhood Hits	299
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI35_HUMAN
NC score	0.909654 (rank : 39)	θ value	2.86786e-30 (rank : 41)
Query Neighborhood Hits	451	Target Neighborhood Hits	382	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
NC score	0.901847 (rank : 40)	θ value	1.2049e-28 (rank : 42)
Query Neighborhood Hits	451	Target Neighborhood Hits	465	Shared Neighborhood Hits	292
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI31_HUMAN
NC score	0.886890 (rank : 41)	θ value	1.01765e-35 (rank : 39)
Query Neighborhood Hits	451	Target Neighborhood Hits	299	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI48_HUMAN
NC score	0.885208 (rank : 42)	θ value	8.65492e-19 (rank : 54)
Query Neighborhood Hits	451	Target Neighborhood Hits	192	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

MEFV_HUMAN
NC score	0.883742 (rank : 43)	θ value	2.49495e-50 (rank : 23)
Query Neighborhood Hits	451	Target Neighborhood Hits	431	Shared Neighborhood Hits	172
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI52_HUMAN
NC score	0.850939 (rank : 44)	θ value	4.16044e-13 (rank : 69)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	186
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI40_HUMAN
NC score	0.832274 (rank : 45)	θ value	7.32683e-18 (rank : 57)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	210
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI73_HUMAN
NC score	0.831614 (rank : 46)	θ value	7.0802e-21 (rank : 51)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	213
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
NC score	0.830326 (rank : 47)	θ value	1.5773e-20 (rank : 52)
Query Neighborhood Hits	451	Target Neighborhood Hits	249	Shared Neighborhood Hits	207
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

RNF39_HUMAN
NC score	0.817232 (rank : 48)	θ value	1.53129e-07 (rank : 94)
Query Neighborhood Hits	451	Target Neighborhood Hits	200	Shared Neighborhood Hits	182
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI65_HUMAN
NC score	0.815930 (rank : 49)	θ value	4.74913e-17 (rank : 58)
Query Neighborhood Hits	451	Target Neighborhood Hits	330	Shared Neighborhood Hits	245
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RFPL3_HUMAN
NC score	0.814731 (rank : 50)	θ value	8.10077e-17 (rank : 59)
Query Neighborhood Hits	451	Target Neighborhood Hits	134	Shared Neighborhood Hits	123
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL1_HUMAN
NC score	0.805363 (rank : 51)	θ value	1.52774e-15 (rank : 65)
Query Neighborhood Hits	451	Target Neighborhood Hits	119	Shared Neighborhood Hits	111
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI65_MOUSE
NC score	0.802572 (rank : 52)	θ value	1.058e-16 (rank : 60)
Query Neighborhood Hits	451	Target Neighborhood Hits	340	Shared Neighborhood Hits	244
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RFPL2_HUMAN
NC score	0.802077 (rank : 53)	θ value	1.16975e-15 (rank : 63)
Query Neighborhood Hits	451	Target Neighborhood Hits	126	Shared Neighborhood Hits	113
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

ERMAP_HUMAN
NC score	0.797025 (rank : 54)	θ value	1.12775e-26 (rank : 43)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	81
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI14_HUMAN
NC score	0.772368 (rank : 55)	θ value	5.25075e-16 (rank : 62)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	120
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
NC score	0.771206 (rank : 56)	θ value	1.80886e-08 (rank : 85)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI13_HUMAN
NC score	0.770145 (rank : 57)	θ value	4.02038e-16 (rank : 61)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	207
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
NC score	0.769728 (rank : 58)	θ value	3.40345e-15 (rank : 66)
Query Neighborhood Hits	451	Target Neighborhood Hits	282	Shared Neighborhood Hits	209
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

ERMAP_MOUSE
NC score	0.762015 (rank : 59)	θ value	1.92365e-26 (rank : 44)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

BTNL9_HUMAN
NC score	0.741331 (rank : 60)	θ value	1.16704e-23 (rank : 46)
Query Neighborhood Hits	451	Target Neighborhood Hits	125	Shared Neighborhood Hits	83
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BTNL3_HUMAN
NC score	0.736750 (rank : 61)	θ value	4.9032e-22 (rank : 50)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT2A2_HUMAN
NC score	0.734076 (rank : 62)	θ value	1.47631e-18 (rank : 55)
Query Neighborhood Hits	451	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI59_MOUSE
NC score	0.733855 (rank : 63)	θ value	1.02475e-11 (rank : 72)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	215
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

BT3A3_HUMAN
NC score	0.732854 (rank : 64)	θ value	6.18819e-25 (rank : 45)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

TRI25_MOUSE
NC score	0.730798 (rank : 65)	θ value	1.02475e-11 (rank : 71)
Query Neighborhood Hits	451	Target Neighborhood Hits	446	Shared Neighborhood Hits	269
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI59_HUMAN
NC score	0.729586 (rank : 66)	θ value	6.64225e-11 (rank : 76)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	211
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

BT1A1_MOUSE
NC score	0.729378 (rank : 67)	θ value	3.75424e-22 (rank : 48)
Query Neighborhood Hits	451	Target Neighborhood Hits	252	Shared Neighborhood Hits	81
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A1_HUMAN
NC score	0.726268 (rank : 68)	θ value	4.9032e-22 (rank : 49)
Query Neighborhood Hits	451	Target Neighborhood Hits	229	Shared Neighborhood Hits	83
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TRI25_HUMAN
NC score	0.723767 (rank : 69)	θ value	3.89403e-11 (rank : 75)
Query Neighborhood Hits	451	Target Neighborhood Hits	472	Shared Neighborhood Hits	279
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

BT2A1_HUMAN
NC score	0.722409 (rank : 70)	θ value	1.92812e-18 (rank : 56)
Query Neighborhood Hits	451	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A3_HUMAN
NC score	0.720597 (rank : 71)	θ value	1.52774e-15 (rank : 64)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	77
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT1A1_HUMAN
NC score	0.720156 (rank : 72)	θ value	1.5242e-23 (rank : 47)
Query Neighborhood Hits	451	Target Neighborhood Hits	322	Shared Neighborhood Hits	81
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BTNL8_HUMAN
NC score	0.718959 (rank : 73)	θ value	2.06002e-20 (rank : 53)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

MEFV_MOUSE
NC score	0.705724 (rank : 74)	θ value	1.86753e-13 (rank : 67)
Query Neighborhood Hits	451	Target Neighborhood Hits	236	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRIM8_MOUSE
NC score	0.692071 (rank : 75)	θ value	5.62301e-10 (rank : 80)
Query Neighborhood Hits	451	Target Neighborhood Hits	674	Shared Neighborhood Hits	300
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.691754 (rank : 76)	θ value	4.30538e-10 (rank : 79)
Query Neighborhood Hits	451	Target Neighborhood Hits	650	Shared Neighborhood Hits	303
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BSPRY_MOUSE
NC score	0.690903 (rank : 77)	θ value	1.09739e-05 (rank : 101)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_HUMAN
NC score	0.688372 (rank : 78)	θ value	3.19293e-05 (rank : 105)
Query Neighborhood Hits	451	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI16_MOUSE
NC score	0.674041 (rank : 79)	θ value	1.17247e-07 (rank : 92)
Query Neighborhood Hits	451	Target Neighborhood Hits	196	Shared Neighborhood Hits	135
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_HUMAN
NC score	0.665248 (rank : 80)	θ value	8.40245e-06 (rank : 100)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI47_MOUSE
NC score	0.660808 (rank : 81)	θ value	3.08544e-08 (rank : 89)
Query Neighborhood Hits	451	Target Neighborhood Hits	295	Shared Neighborhood Hits	215
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI47_HUMAN
NC score	0.648233 (rank : 82)	θ value	6.87365e-08 (rank : 91)
Query Neighborhood Hits	451	Target Neighborhood Hits	286	Shared Neighborhood Hits	216
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI32_HUMAN
NC score	0.635959 (rank : 83)	θ value	2.28291e-11 (rank : 74)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	186
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.632400 (rank : 84)	θ value	1.74796e-11 (rank : 73)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	186
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI63_MOUSE
NC score	0.631953 (rank : 85)	θ value	6.21693e-09 (rank : 81)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	183
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI18_HUMAN
NC score	0.628445 (rank : 86)	θ value	1.09739e-05 (rank : 102)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	219
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI63_HUMAN
NC score	0.626280 (rank : 87)	θ value	5.26297e-08 (rank : 90)
Query Neighborhood Hits	451	Target Neighborhood Hits	298	Shared Neighborhood Hits	199
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

ZN179_HUMAN
NC score	0.623491 (rank : 88)	θ value	0.00035302 (rank : 119)
Query Neighborhood Hits	451	Target Neighborhood Hits	178	Shared Neighborhood Hits	151
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI44_MOUSE
NC score	0.622123 (rank : 89)	θ value	1.38499e-08 (rank : 84)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI18_MOUSE
NC score	0.613212 (rank : 90)	θ value	2.44474e-05 (rank : 104)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	221
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI55_HUMAN
NC score	0.612278 (rank : 91)	θ value	1.17247e-07 (rank : 93)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	184
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI44_HUMAN
NC score	0.610507 (rank : 92)	θ value	2.36244e-08 (rank : 86)
Query Neighborhood Hits	451	Target Neighborhood Hits	393	Shared Neighborhood Hits	129
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

SPRY4_MOUSE
NC score	0.604900 (rank : 93)	θ value	0.279714 (rank : 236)
Query Neighborhood Hits	451	Target Neighborhood Hits	82	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRIM1_HUMAN
NC score	0.599510 (rank : 94)	θ value	2.21117e-06 (rank : 97)
Query Neighborhood Hits	451	Target Neighborhood Hits	345	Shared Neighborhood Hits	238
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.595577 (rank : 95)	θ value	1.87187e-05 (rank : 103)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	239
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI37_HUMAN
NC score	0.590639 (rank : 96)	θ value	3.08544e-08 (rank : 87)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	182
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.590271 (rank : 97)	θ value	3.08544e-08 (rank : 88)
Query Neighborhood Hits	451	Target Neighborhood Hits	316	Shared Neighborhood Hits	182
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRIM3_MOUSE
NC score	0.586133 (rank : 98)	θ value	3.29651e-10 (rank : 78)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	206
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI54_HUMAN
NC score	0.585538 (rank : 99)	θ value	4.92598e-06 (rank : 98)
Query Neighborhood Hits	451	Target Neighborhood Hits	209	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
NC score	0.584664 (rank : 100)	θ value	6.43352e-06 (rank : 99)
Query Neighborhood Hits	451	Target Neighborhood Hits	197	Shared Neighborhood Hits	168
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM3_HUMAN
NC score	0.582774 (rank : 101)	θ value	3.29651e-10 (rank : 77)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	212
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

SPRY4_HUMAN
NC score	0.581214 (rank : 102)	θ value	5.27518 (rank : 394)
Query Neighborhood Hits	451	Target Neighborhood Hits	79	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRIM2_HUMAN
NC score	0.576418 (rank : 103)	θ value	1.06045e-08 (rank : 82)
Query Neighborhood Hits	451	Target Neighborhood Hits	330	Shared Neighborhood Hits	211
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.575273 (rank : 104)	θ value	1.06045e-08 (rank : 83)
Query Neighborhood Hits	451	Target Neighborhood Hits	331	Shared Neighborhood Hits	210
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI29_MOUSE
NC score	0.572619 (rank : 105)	θ value	4.16044e-13 (rank : 68)
Query Neighborhood Hits	451	Target Neighborhood Hits	306	Shared Neighborhood Hits	160
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI29_HUMAN
NC score	0.565070 (rank : 106)	θ value	5.43371e-13 (rank : 70)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	145
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

BRCA1_HUMAN
NC score	0.542953 (rank : 107)	θ value	1.99992e-07 (rank : 95)
Query Neighborhood Hits	451	Target Neighborhood Hits	381	Shared Neighborhood Hits	210
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BFAR_HUMAN
NC score	0.531648 (rank : 108)	θ value	0.00102713 (rank : 123)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BRCA1_MOUSE
NC score	0.527751 (rank : 109)	θ value	7.59969e-07 (rank : 96)
Query Neighborhood Hits	451	Target Neighborhood Hits	436	Shared Neighborhood Hits	199
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

ZN313_MOUSE
NC score	0.527518 (rank : 110)	θ value	7.1131e-05 (rank : 107)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	185
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RN125_MOUSE
NC score	0.523538 (rank : 111)	θ value	0.000121331 (rank : 110)
Query Neighborhood Hits	451	Target Neighborhood Hits	220	Shared Neighborhood Hits	162
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

ZN313_HUMAN
NC score	0.517849 (rank : 112)	θ value	9.29e-05 (rank : 108)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

BFAR_MOUSE
NC score	0.517243 (rank : 113)	θ value	0.00509761 (rank : 148)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RN168_HUMAN
NC score	0.515129 (rank : 114)	θ value	0.00102713 (rank : 124)
Query Neighborhood Hits	451	Target Neighborhood Hits	370	Shared Neighborhood Hits	206
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN125_HUMAN
NC score	0.510018 (rank : 115)	θ value	0.00020696 (rank : 112)
Query Neighborhood Hits	451	Target Neighborhood Hits	230	Shared Neighborhood Hits	171
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

PEX10_HUMAN
NC score	0.508306 (rank : 116)	θ value	0.00134147 (rank : 129)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	170
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN166_HUMAN
NC score	0.507279 (rank : 117)	θ value	0.000602161 (rank : 121)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	176
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.498359 (rank : 118)	θ value	0.00175202 (rank : 139)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	180
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_MOUSE
NC score	0.496154 (rank : 119)	θ value	0.00665767 (rank : 152)
Query Neighborhood Hits	451	Target Neighborhood Hits	440	Shared Neighborhood Hits	227
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI46_MOUSE
NC score	0.481779 (rank : 120)	θ value	0.000158464 (rank : 111)
Query Neighborhood Hits	451	Target Neighborhood Hits	287	Shared Neighborhood Hits	195
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.480119 (rank : 121)	θ value	0.00134147 (rank : 135)
Query Neighborhood Hits	451	Target Neighborhood Hits	291	Shared Neighborhood Hits	196
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RNF8_MOUSE
NC score	0.464809 (rank : 122)	θ value	0.00390308 (rank : 147)
Query Neighborhood Hits	451	Target Neighborhood Hits	618	Shared Neighborhood Hits	297
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI36_HUMAN
NC score	0.453389 (rank : 123)	θ value	0.00228821 (rank : 142)
Query Neighborhood Hits	451	Target Neighborhood Hits	282	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

RNF8_HUMAN
NC score	0.446516 (rank : 124)	θ value	0.00509761 (rank : 149)
Query Neighborhood Hits	451	Target Neighborhood Hits	622	Shared Neighborhood Hits	288
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI56_HUMAN
NC score	0.446121 (rank : 125)	θ value	0.000270298 (rank : 114)
Query Neighborhood Hits	451	Target Neighborhood Hits	339	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI36_MOUSE
NC score	0.443478 (rank : 126)	θ value	0.00175202 (rank : 140)
Query Neighborhood Hits	451	Target Neighborhood Hits	266	Shared Neighborhood Hits	187
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI56_MOUSE
NC score	0.442944 (rank : 127)	θ value	0.00298849 (rank : 146)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRIM9_HUMAN
NC score	0.438899 (rank : 128)	θ value	0.0330416 (rank : 176)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	179
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

RING1_HUMAN
NC score	0.437744 (rank : 129)	θ value	0.00035302 (rank : 115)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	156
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRIM9_MOUSE
NC score	0.435241 (rank : 130)	θ value	0.0330416 (rank : 177)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	178
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RING1_MOUSE
NC score	0.430691 (rank : 131)	θ value	0.00035302 (rank : 116)
Query Neighborhood Hits	451	Target Neighborhood Hits	220	Shared Neighborhood Hits	156
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RAG1_HUMAN
NC score	0.418512 (rank : 132)	θ value	5.44631e-05 (rank : 106)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	143
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RING2_MOUSE
NC score	0.408822 (rank : 133)	θ value	0.00035302 (rank : 118)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.408754 (rank : 134)	θ value	0.00035302 (rank : 117)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	152
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RNF41_MOUSE
NC score	0.408723 (rank : 135)	θ value	0.00134147 (rank : 131)
Query Neighborhood Hits	451	Target Neighborhood Hits	224	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.408410 (rank : 136)	θ value	0.00134147 (rank : 130)
Query Neighborhood Hits	451	Target Neighborhood Hits	226	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RAG1_MOUSE
NC score	0.405044 (rank : 137)	θ value	0.00665767 (rank : 151)
Query Neighborhood Hits	451	Target Neighborhood Hits	189	Shared Neighborhood Hits	144
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RNF4_HUMAN
NC score	0.388715 (rank : 138)	θ value	0.0431538 (rank : 182)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	155
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.382379 (rank : 139)	θ value	0.0431538 (rank : 183)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	156
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RN183_HUMAN
NC score	0.375348 (rank : 140)	θ value	0.813845 (rank : 282)
Query Neighborhood Hits	451	Target Neighborhood Hits	126	Shared Neighborhood Hits	111
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN169_HUMAN
NC score	0.373292 (rank : 141)	θ value	0.0148317 (rank : 159)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	110
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN185_HUMAN
NC score	0.370993 (rank : 142)	θ value	1.06291 (rank : 299)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	151
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.370535 (rank : 143)	θ value	1.06291 (rank : 300)
Query Neighborhood Hits	451	Target Neighborhood Hits	211	Shared Neighborhood Hits	151
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRAF6_MOUSE
NC score	0.366342 (rank : 144)	θ value	0.000270298 (rank : 113)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	176
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

CHFR_HUMAN
NC score	0.363197 (rank : 145)	θ value	0.125558 (rank : 209)
Query Neighborhood Hits	451	Target Neighborhood Hits	255	Shared Neighborhood Hits	166
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF5_HUMAN
NC score	0.362746 (rank : 146)	θ value	0.47712 (rank : 255)
Query Neighborhood Hits	451	Target Neighborhood Hits	206	Shared Neighborhood Hits	146
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.361947 (rank : 147)	θ value	0.365318 (rank : 244)
Query Neighborhood Hits	451	Target Neighborhood Hits	206	Shared Neighborhood Hits	145
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI42_HUMAN
NC score	0.358944 (rank : 148)	θ value	0.000602161 (rank : 122)
Query Neighborhood Hits	451	Target Neighborhood Hits	283	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
NC score	0.357369 (rank : 149)	θ value	0.00665767 (rank : 153)
Query Neighborhood Hits	451	Target Neighborhood Hits	316	Shared Neighborhood Hits	134
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

CHFR_MOUSE
NC score	0.357044 (rank : 150)	θ value	0.125558 (rank : 210)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	167
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRAF6_HUMAN
NC score	0.354688 (rank : 151)	θ value	0.00298849 (rank : 145)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RN146_HUMAN
NC score	0.332514 (rank : 152)	θ value	0.0736092 (rank : 197)
Query Neighborhood Hits	451	Target Neighborhood Hits	162	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.330277 (rank : 153)	θ value	0.0736092 (rank : 198)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

DTX3_MOUSE
NC score	0.327154 (rank : 154)	θ value	0.279714 (rank : 231)
Query Neighborhood Hits	451	Target Neighborhood Hits	202	Shared Neighborhood Hits	149
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RAD18_MOUSE
NC score	0.325760 (rank : 155)	θ value	0.0563607 (rank : 192)
Query Neighborhood Hits	451	Target Neighborhood Hits	230	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN183_MOUSE
NC score	0.319798 (rank : 156)	θ value	3.0926 (rank : 353)
Query Neighborhood Hits	451	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

DTX3_HUMAN
NC score	0.314805 (rank : 157)	θ value	0.47712 (rank : 248)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RN141_HUMAN
NC score	0.306056 (rank : 158)	θ value	0.0736092 (rank : 195)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.305058 (rank : 159)	θ value	0.0736092 (rank : 196)
Query Neighborhood Hits	451	Target Neighborhood Hits	200	Shared Neighborhood Hits	144
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

UHRF2_HUMAN
NC score	0.304430 (rank : 160)	θ value	0.0431538 (rank : 185)
Query Neighborhood Hits	451	Target Neighborhood Hits	269	Shared Neighborhood Hits	159
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

SMRA3_HUMAN
NC score	0.304186 (rank : 161)	θ value	0.00134147 (rank : 132)
Query Neighborhood Hits	451	Target Neighborhood Hits	265	Shared Neighborhood Hits	175
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

UHRF2_MOUSE
NC score	0.299555 (rank : 162)	θ value	0.0431538 (rank : 186)
Query Neighborhood Hits	451	Target Neighborhood Hits	275	Shared Neighborhood Hits	158
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

RAD18_HUMAN
NC score	0.298278 (rank : 163)	θ value	0.0563607 (rank : 191)
Query Neighborhood Hits	451	Target Neighborhood Hits	284	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RFWD2_MOUSE
NC score	0.295611 (rank : 164)	θ value	0.00869519 (rank : 155)
Query Neighborhood Hits	451	Target Neighborhood Hits	535	Shared Neighborhood Hits	192
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.295610 (rank : 165)	θ value	0.00298849 (rank : 144)
Query Neighborhood Hits	451	Target Neighborhood Hits	518	Shared Neighborhood Hits	188
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

CM007_MOUSE
NC score	0.293745 (rank : 166)	θ value	0.0193708 (rank : 160)
Query Neighborhood Hits	451	Target Neighborhood Hits	416	Shared Neighborhood Hits	190
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

BIRC7_HUMAN
NC score	0.289345 (rank : 167)	θ value	0.279714 (rank : 230)
Query Neighborhood Hits	451	Target Neighborhood Hits	185	Shared Neighborhood Hits	130
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

SMRA3_MOUSE
NC score	0.287049 (rank : 168)	θ value	0.00134147 (rank : 133)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	166
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TIF1G_HUMAN
NC score	0.281463 (rank : 169)	θ value	0.00102713 (rank : 125)
Query Neighborhood Hits	451	Target Neighborhood Hits	410	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.276949 (rank : 170)	θ value	0.00134147 (rank : 134)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	131
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI45_HUMAN
NC score	0.276012 (rank : 171)	θ value	0.0431538 (rank : 184)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

PML_HUMAN
NC score	0.272715 (rank : 172)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	119
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

CM007_HUMAN
NC score	0.266177 (rank : 173)	θ value	0.0330416 (rank : 172)
Query Neighborhood Hits	451	Target Neighborhood Hits	422	Shared Neighborhood Hits	196
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

LNX1_MOUSE
NC score	0.262615 (rank : 174)	θ value	0.000461057 (rank : 120)
Query Neighborhood Hits	451	Target Neighborhood Hits	377	Shared Neighborhood Hits	157
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.260357 (rank : 175)	θ value	0.00175202 (rank : 137)
Query Neighborhood Hits	451	Target Neighborhood Hits	379	Shared Neighborhood Hits	165
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI45_MOUSE
NC score	0.259110 (rank : 176)	θ value	1.06291 (rank : 301)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	112
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

UHRF1_MOUSE
NC score	0.258631 (rank : 177)	θ value	0.0330416 (rank : 178)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	158
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PCGF6_MOUSE
NC score	0.256964 (rank : 178)	θ value	0.21417 (rank : 229)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	124
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRAF5_MOUSE
NC score	0.255222 (rank : 179)	θ value	0.813845 (rank : 285)
Query Neighborhood Hits	451	Target Neighborhood Hits	355	Shared Neighborhood Hits	192
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

LNX2_MOUSE
NC score	0.254421 (rank : 180)	θ value	0.00175202 (rank : 138)
Query Neighborhood Hits	451	Target Neighborhood Hits	407	Shared Neighborhood Hits	173
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.253410 (rank : 181)	θ value	0.00228821 (rank : 141)
Query Neighborhood Hits	451	Target Neighborhood Hits	389	Shared Neighborhood Hits	172
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PCGF6_HUMAN
NC score	0.251236 (rank : 182)	θ value	1.06291 (rank : 298)
Query Neighborhood Hits	451	Target Neighborhood Hits	178	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

UHRF1_HUMAN
NC score	0.248375 (rank : 183)	θ value	0.0961366 (rank : 206)
Query Neighborhood Hits	451	Target Neighborhood Hits	272	Shared Neighborhood Hits	160
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

PML_MOUSE
NC score	0.244377 (rank : 184)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	451	Target Neighborhood Hits	246	Shared Neighborhood Hits	134
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

R113B_HUMAN
NC score	0.242288 (rank : 185)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TIF1B_HUMAN
NC score	0.240358 (rank : 186)	θ value	0.62314 (rank : 268)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	117
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.234989 (rank : 187)	θ value	0.813845 (rank : 284)
Query Neighborhood Hits	451	Target Neighborhood Hits	276	Shared Neighborhood Hits	112
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRAF5_HUMAN
NC score	0.229858 (rank : 188)	θ value	0.62314 (rank : 271)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	193
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

R113A_HUMAN
NC score	0.225749 (rank : 189)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	132
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RC3H1_MOUSE
NC score	0.224413 (rank : 190)	θ value	0.0252991 (rank : 170)
Query Neighborhood Hits	451	Target Neighborhood Hits	244	Shared Neighborhood Hits	129
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRAF4_HUMAN
NC score	0.223418 (rank : 191)	θ value	0.62314 (rank : 270)
Query Neighborhood Hits	451	Target Neighborhood Hits	373	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

PZRN3_MOUSE
NC score	0.223347 (rank : 192)	θ value	0.0252991 (rank : 169)
Query Neighborhood Hits	451	Target Neighborhood Hits	447	Shared Neighborhood Hits	179
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.221220 (rank : 193)	θ value	0.0252991 (rank : 168)
Query Neighborhood Hits	451	Target Neighborhood Hits	461	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
NC score	0.218661 (rank : 194)	θ value	0.00869519 (rank : 154)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	184
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TOPRS_MOUSE
NC score	0.215791 (rank : 195)	θ value	0.163984 (rank : 218)
Query Neighborhood Hits	451	Target Neighborhood Hits	263	Shared Neighborhood Hits	130
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RC3H1_HUMAN
NC score	0.214970 (rank : 196)	θ value	0.0193708 (rank : 164)
Query Neighborhood Hits	451	Target Neighborhood Hits	433	Shared Neighborhood Hits	132
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TOPRS_HUMAN
NC score	0.212538 (rank : 197)	θ value	0.163984 (rank : 217)
Query Neighborhood Hits	451	Target Neighborhood Hits	286	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

PCGF4_MOUSE
NC score	0.212165 (rank : 198)	θ value	0.813845 (rank : 281)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.211788 (rank : 199)	θ value	0.813845 (rank : 280)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	113
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF2_MOUSE
NC score	0.199656 (rank : 200)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	111
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.199640 (rank : 201)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	112
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

BT3A2_HUMAN
NC score	0.198551 (rank : 202)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	451	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

TRAF2_MOUSE
NC score	0.194805 (rank : 203)	θ value	1.81305 (rank : 320)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	133
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

BTNL1_MOUSE
NC score	0.191402 (rank : 204)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

RBBP6_MOUSE
NC score	0.191365 (rank : 205)	θ value	0.0193708 (rank : 163)
Query Neighborhood Hits	451	Target Neighborhood Hits	1014	Shared Neighborhood Hits	176
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TIF1A_HUMAN
NC score	0.190301 (rank : 206)	θ value	0.0330416 (rank : 175)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	111
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRAF3_MOUSE
NC score	0.189890 (rank : 207)	θ value	0.47712 (rank : 257)
Query Neighborhood Hits	451	Target Neighborhood Hits	476	Shared Neighborhood Hits	209
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF2_HUMAN
NC score	0.189435 (rank : 208)	θ value	3.0926 (rank : 359)
Query Neighborhood Hits	451	Target Neighborhood Hits	402	Shared Neighborhood Hits	136
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

BTNL2_HUMAN
NC score	0.184384 (rank : 209)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	451	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

TRAF7_HUMAN
NC score	0.183661 (rank : 210)	θ value	1.38821 (rank : 309)
Query Neighborhood Hits	451	Target Neighborhood Hits	482	Shared Neighborhood Hits	162
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
NC score	0.183153 (rank : 211)	θ value	1.38821 (rank : 310)
Query Neighborhood Hits	451	Target Neighborhood Hits	470	Shared Neighborhood Hits	158
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

NHLC1_MOUSE
NC score	0.182900 (rank : 212)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAF3_HUMAN
NC score	0.181917 (rank : 213)	θ value	0.62314 (rank : 269)
Query Neighborhood Hits	451	Target Neighborhood Hits	463	Shared Neighborhood Hits	202
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

MOG_HUMAN
NC score	0.179679 (rank : 214)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	451	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
NC score	0.179045 (rank : 215)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	451	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

TRAIP_HUMAN
NC score	0.178366 (rank : 216)	θ value	1.81305 (rank : 321)
Query Neighborhood Hits	451	Target Neighborhood Hits	780	Shared Neighborhood Hits	207
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

RBBP6_HUMAN
NC score	0.176989 (rank : 217)	θ value	0.0193708 (rank : 162)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	187
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NHLC1_HUMAN
NC score	0.175609 (rank : 218)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	451	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

MAT1_MOUSE
NC score	0.174157 (rank : 219)	θ value	0.0563607 (rank : 189)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	106
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

AMFR2_HUMAN
NC score	0.173684 (rank : 220)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
NC score	0.173500 (rank : 221)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	451	Target Neighborhood Hits	208	Shared Neighborhood Hits	120
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

MAT1_HUMAN
NC score	0.173071 (rank : 222)	θ value	0.0563607 (rank : 188)
Query Neighborhood Hits	451	Target Neighborhood Hits	179	Shared Neighborhood Hits	95
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

RN152_MOUSE
NC score	0.170643 (rank : 223)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN152_HUMAN
NC score	0.166461 (rank : 224)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	451	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

MNAB_HUMAN
NC score	0.162805 (rank : 225)	θ value	3.0926 (rank : 346)
Query Neighborhood Hits	451	Target Neighborhood Hits	196	Shared Neighborhood Hits	113
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

TIF1A_MOUSE
NC score	0.162763 (rank : 226)	θ value	0.365318 (rank : 245)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	97
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRAIP_MOUSE
NC score	0.162289 (rank : 227)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	451	Target Neighborhood Hits	745	Shared Neighborhood Hits	209
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

DTX3L_HUMAN
NC score	0.161785 (rank : 228)	θ value	0.47712 (rank : 247)
Query Neighborhood Hits	451	Target Neighborhood Hits	187	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

MNAB_MOUSE
NC score	0.160649 (rank : 229)	θ value	3.0926 (rank : 347)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	111
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

UB7I3_MOUSE
NC score	0.158210 (rank : 230)	θ value	0.00102713 (rank : 126)
Query Neighborhood Hits	451	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

BARD1_HUMAN
NC score	0.145090 (rank : 231)	θ value	0.125558 (rank : 208)
Query Neighborhood Hits	451	Target Neighborhood Hits	427	Shared Neighborhood Hits	105
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
NC score	0.143599 (rank : 232)	θ value	0.163984 (rank : 213)
Query Neighborhood Hits	451	Target Neighborhood Hits	411	Shared Neighborhood Hits	103
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

RNF32_HUMAN
NC score	0.138366 (rank : 233)	θ value	1.81305 (rank : 318)
Query Neighborhood Hits	451	Target Neighborhood Hits	133	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

UB7I3_HUMAN
NC score	0.135415 (rank : 234)	θ value	0.0736092 (rank : 199)
Query Neighborhood Hits	451	Target Neighborhood Hits	136	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

TRAF4_MOUSE
NC score	0.133839 (rank : 235)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	451	Target Neighborhood Hits	338	Shared Neighborhood Hits	106
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

CBL_HUMAN
NC score	0.133104 (rank : 236)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	451	Target Neighborhood Hits	353	Shared Neighborhood Hits	135
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

ARD1_MOUSE
NC score	0.131316 (rank : 237)	θ value	0.0431538 (rank : 179)
Query Neighborhood Hits	451	Target Neighborhood Hits	573	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

CBL_MOUSE
NC score	0.130743 (rank : 238)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	451	Target Neighborhood Hits	426	Shared Neighborhood Hits	145
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

BRE1B_MOUSE
NC score	0.129142 (rank : 239)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	451	Target Neighborhood Hits	970	Shared Neighborhood Hits	287
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CBLB_MOUSE
NC score	0.128776 (rank : 240)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	132
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

BRE1B_HUMAN
NC score	0.128237 (rank : 241)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	451	Target Neighborhood Hits	1040	Shared Neighborhood Hits	291
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CBLB_HUMAN
NC score	0.127586 (rank : 242)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	130
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLC_MOUSE
NC score	0.127521 (rank : 243)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	451	Target Neighborhood Hits	186	Shared Neighborhood Hits	119
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

BRAP_HUMAN
NC score	0.127478 (rank : 244)	θ value	0.813845 (rank : 273)
Query Neighborhood Hits	451	Target Neighborhood Hits	560	Shared Neighborhood Hits	186
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

ARD1_HUMAN
NC score	0.126448 (rank : 245)	θ value	0.125558 (rank : 207)
Query Neighborhood Hits	451	Target Neighborhood Hits	621	Shared Neighborhood Hits	88
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

CBLC_HUMAN
NC score	0.124887 (rank : 246)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	451	Target Neighborhood Hits	173	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

RNF34_MOUSE
NC score	0.122805 (rank : 247)	θ value	2.36792 (rank : 335)
Query Neighborhood Hits	451	Target Neighborhood Hits	160	Shared Neighborhood Hits	73
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF32_MOUSE
NC score	0.121511 (rank : 248)	θ value	6.88961 (rank : 416)
Query Neighborhood Hits	451	Target Neighborhood Hits	129	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
NC score	0.120404 (rank : 249)	θ value	2.36792 (rank : 334)
Query Neighborhood Hits	451	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

BIRC8_HUMAN
NC score	0.119750 (rank : 250)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CNOT4_HUMAN
NC score	0.117602 (rank : 251)	θ value	1.06291 (rank : 288)
Query Neighborhood Hits	451	Target Neighborhood Hits	207	Shared Neighborhood Hits	44
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BRE1A_HUMAN
NC score	0.113925 (rank : 252)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	451	Target Neighborhood Hits	1071	Shared Neighborhood Hits	275
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
NC score	0.112531 (rank : 253)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	451	Target Neighborhood Hits	1025	Shared Neighborhood Hits	269
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CNOT4_MOUSE
NC score	0.112137 (rank : 254)	θ value	1.06291 (rank : 289)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BRAP_MOUSE
NC score	0.111243 (rank : 255)	θ value	1.06291 (rank : 286)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	153
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

RKHD1_HUMAN
NC score	0.110144 (rank : 256)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

MGRN1_MOUSE
NC score	0.103219 (rank : 257)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	451	Target Neighborhood Hits	149	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

CD276_MOUSE
NC score	0.103088 (rank : 258)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

PJA1_HUMAN
NC score	0.103021 (rank : 259)	θ value	6.88961 (rank : 414)
Query Neighborhood Hits	451	Target Neighborhood Hits	159	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RN123_MOUSE
NC score	0.102257 (rank : 260)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	451	Target Neighborhood Hits	174	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_HUMAN
NC score	0.102088 (rank : 261)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	451	Target Neighborhood Hits	175	Shared Neighborhood Hits	107
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

MGRN1_HUMAN
NC score	0.099109 (rank : 262)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	451	Target Neighborhood Hits	192	Shared Neighborhood Hits	83
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

BIRC3_HUMAN
NC score	0.098719 (rank : 263)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	451	Target Neighborhood Hits	133	Shared Neighborhood Hits	69
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_HUMAN
NC score	0.098693 (rank : 264)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	451	Target Neighborhood Hits	142	Shared Neighborhood Hits	75
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

TRI66_MOUSE
NC score	0.096438 (rank : 265)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	98
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

MIB1_HUMAN
NC score	0.095858 (rank : 266)	θ value	0.00134147 (rank : 127)
Query Neighborhood Hits	451	Target Neighborhood Hits	470	Shared Neighborhood Hits	97
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

CCD46_HUMAN
NC score	0.095683 (rank : 267)	θ value	0.0113563 (rank : 156)
Query Neighborhood Hits	451	Target Neighborhood Hits	1430	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MIB1_MOUSE
NC score	0.095673 (rank : 268)	θ value	0.00134147 (rank : 128)
Query Neighborhood Hits	451	Target Neighborhood Hits	471	Shared Neighborhood Hits	97
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

GCC1_HUMAN
NC score	0.094667 (rank : 269)	θ value	0.0330416 (rank : 174)
Query Neighborhood Hits	451	Target Neighborhood Hits	887	Shared Neighborhood Hits	187
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

FSD1L_MOUSE
NC score	0.093962 (rank : 270)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	451	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GOGA4_MOUSE
NC score	0.093810 (rank : 271)	θ value	0.279714 (rank : 232)
Query Neighborhood Hits	451	Target Neighborhood Hits	1939	Shared Neighborhood Hits	259
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RN103_HUMAN
NC score	0.093547 (rank : 272)	θ value	0.0961366 (rank : 202)
Query Neighborhood Hits	451	Target Neighborhood Hits	153	Shared Neighborhood Hits	65
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
NC score	0.093348 (rank : 273)	θ value	0.0961366 (rank : 203)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

BIRC2_MOUSE
NC score	0.092974 (rank : 274)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

ZSWM2_HUMAN
NC score	0.092723 (rank : 275)	θ value	4.03905 (rank : 372)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

TRI66_HUMAN
NC score	0.092665 (rank : 276)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	451	Target Neighborhood Hits	479	Shared Neighborhood Hits	95
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CD276_HUMAN
NC score	0.092604 (rank : 277)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CP250_HUMAN
NC score	0.092233 (rank : 278)	θ value	1.06291 (rank : 290)
Query Neighborhood Hits	451	Target Neighborhood Hits	1805	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CT2NL_HUMAN
NC score	0.091587 (rank : 279)	θ value	0.00298849 (rank : 143)
Query Neighborhood Hits	451	Target Neighborhood Hits	1059	Shared Neighborhood Hits	184
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ICOSL_HUMAN
NC score	0.090855 (rank : 280)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	451	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

CENPF_HUMAN
NC score	0.090519 (rank : 281)	θ value	0.0148317 (rank : 158)
Query Neighborhood Hits	451	Target Neighborhood Hits	1932	Shared Neighborhood Hits	258
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PCNT_HUMAN
NC score	0.090330 (rank : 282)	θ value	0.62314 (rank : 266)
Query Neighborhood Hits	451	Target Neighborhood Hits	1551	Shared Neighborhood Hits	228
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

GOGB1_HUMAN
NC score	0.089413 (rank : 283)	θ value	2.36792 (rank : 326)
Query Neighborhood Hits	451	Target Neighborhood Hits	2297	Shared Neighborhood Hits	278
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LRSM1_HUMAN
NC score	0.089333 (rank : 284)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	451	Target Neighborhood Hits	1078	Shared Neighborhood Hits	222
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MKRN2_MOUSE
NC score	0.088951 (rank : 285)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	451	Target Neighborhood Hits	130	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

SYCP1_MOUSE
NC score	0.088934 (rank : 286)	θ value	0.279714 (rank : 237)
Query Neighborhood Hits	451	Target Neighborhood Hits	1456	Shared Neighborhood Hits	235
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MKRN4_HUMAN
NC score	0.088617 (rank : 287)	θ value	5.27518 (rank : 385)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	83
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MKRN2_HUMAN
NC score	0.088368 (rank : 288)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	451	Target Neighborhood Hits	129	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

PEX2_MOUSE
NC score	0.088327 (rank : 289)	θ value	2.36792 (rank : 333)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

CCD41_MOUSE
NC score	0.088054 (rank : 290)	θ value	0.0252991 (rank : 165)
Query Neighborhood Hits	451	Target Neighborhood Hits	1399	Shared Neighborhood Hits	219
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

INCE_HUMAN
NC score	0.087832 (rank : 291)	θ value	0.21417 (rank : 225)
Query Neighborhood Hits	451	Target Neighborhood Hits	978	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

GOGA4_HUMAN
NC score	0.087289 (rank : 292)	θ value	0.47712 (rank : 249)
Query Neighborhood Hits	451	Target Neighborhood Hits	2034	Shared Neighborhood Hits	266
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

NIN_HUMAN
NC score	0.086724 (rank : 293)	θ value	6.88961 (rank : 412)
Query Neighborhood Hits	451	Target Neighborhood Hits	1416	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CCD46_MOUSE
NC score	0.086046 (rank : 294)	θ value	4.03905 (rank : 362)
Query Neighborhood Hits	451	Target Neighborhood Hits	1405	Shared Neighborhood Hits	229
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GCC2_MOUSE
NC score	0.085999 (rank : 295)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	451	Target Neighborhood Hits	1619	Shared Neighborhood Hits	246
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CCD41_HUMAN
NC score	0.085355 (rank : 296)	θ value	0.163984 (rank : 214)
Query Neighborhood Hits	451	Target Neighborhood Hits	1139	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CT2NL_MOUSE
NC score	0.085187 (rank : 297)	θ value	0.0193708 (rank : 161)
Query Neighborhood Hits	451	Target Neighborhood Hits	902	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NUMA1_HUMAN
NC score	0.084405 (rank : 298)	θ value	0.47712 (rank : 253)
Query Neighborhood Hits	451	Target Neighborhood Hits	1523	Shared Neighborhood Hits	226
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

GCC1_MOUSE
NC score	0.083829 (rank : 299)	θ value	3.0926 (rank : 342)
Query Neighborhood Hits	451	Target Neighborhood Hits	777	Shared Neighborhood Hits	177
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CF060_HUMAN
NC score	0.083466 (rank : 300)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	451	Target Neighborhood Hits	1270	Shared Neighborhood Hits	234
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

AZI1_MOUSE
NC score	0.083205 (rank : 301)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	451	Target Neighborhood Hits	990	Shared Neighborhood Hits	191
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

PDL1_MOUSE
NC score	0.082509 (rank : 302)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	451	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

RNF26_HUMAN
NC score	0.082304 (rank : 303)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

CP250_MOUSE
NC score	0.082228 (rank : 304)	θ value	2.36792 (rank : 324)
Query Neighborhood Hits	451	Target Neighborhood Hits	1583	Shared Neighborhood Hits	240
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

RBP24_HUMAN
NC score	0.082132 (rank : 305)	θ value	6.88961 (rank : 415)
Query Neighborhood Hits	451	Target Neighborhood Hits	1559	Shared Neighborhood Hits	246
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.082051 (rank : 306)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	451	Target Neighborhood Hits	1558	Shared Neighborhood Hits	246
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

TRHY_HUMAN
NC score	0.081957 (rank : 307)	θ value	0.163984 (rank : 219)
Query Neighborhood Hits	451	Target Neighborhood Hits	1385	Shared Neighborhood Hits	196
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CENPE_HUMAN
NC score	0.081943 (rank : 308)	θ value	0.163984 (rank : 215)
Query Neighborhood Hits	451	Target Neighborhood Hits	2060	Shared Neighborhood Hits	257
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RFFL_HUMAN
NC score	0.081335 (rank : 309)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	451	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

CCD19_HUMAN
NC score	0.081313 (rank : 310)	θ value	0.0961366 (rank : 201)
Query Neighborhood Hits	451	Target Neighborhood Hits	639	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CE290_HUMAN
NC score	0.081257 (rank : 311)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	451	Target Neighborhood Hits	1553	Shared Neighborhood Hits	242
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

EP15R_HUMAN
NC score	0.080812 (rank : 312)	θ value	0.0252991 (rank : 167)
Query Neighborhood Hits	451	Target Neighborhood Hits	1083	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ANR26_HUMAN
NC score	0.080348 (rank : 313)	θ value	0.000121331 (rank : 109)
Query Neighborhood Hits	451	Target Neighborhood Hits	1614	Shared Neighborhood Hits	224
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

T3JAM_HUMAN
NC score	0.080335 (rank : 314)	θ value	0.00509761 (rank : 150)
Query Neighborhood Hits	451	Target Neighborhood Hits	533	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

AZI1_HUMAN
NC score	0.080305 (rank : 315)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	451	Target Neighborhood Hits	1000	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

EP15R_MOUSE
NC score	0.080240 (rank : 316)	θ value	0.0113563 (rank : 157)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	194
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

NIN_MOUSE
NC score	0.079810 (rank : 317)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	451	Target Neighborhood Hits	1376	Shared Neighborhood Hits	216
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

HHLA2_HUMAN
NC score	0.079640 (rank : 318)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

FSD1L_HUMAN
NC score	0.079524 (rank : 319)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

PCNT_MOUSE
NC score	0.079385 (rank : 320)	θ value	0.365318 (rank : 243)
Query Neighborhood Hits	451	Target Neighborhood Hits	1207	Shared Neighborhood Hits	220
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

SDCG8_HUMAN
NC score	0.079247 (rank : 321)	θ value	2.36792 (rank : 336)
Query Neighborhood Hits	451	Target Neighborhood Hits	1002	Shared Neighborhood Hits	200
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

RFFL_MOUSE
NC score	0.078980 (rank : 322)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

CD86_HUMAN
NC score	0.078885 (rank : 323)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	451	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

MIB2_HUMAN
NC score	0.078675 (rank : 324)	θ value	0.47712 (rank : 251)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	91
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

TPR_HUMAN
NC score	0.078646 (rank : 325)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	451	Target Neighborhood Hits	1921	Shared Neighborhood Hits	244
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

NEUL1_HUMAN
NC score	0.078613 (rank : 326)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

PJA1_MOUSE
NC score	0.078163 (rank : 327)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

NEURL_MOUSE
NC score	0.077911 (rank : 328)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	451	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

TRIPB_HUMAN
NC score	0.077883 (rank : 329)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	451	Target Neighborhood Hits	1587	Shared Neighborhood Hits	233
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

EEA1_HUMAN
NC score	0.077617 (rank : 330)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	451	Target Neighborhood Hits	1796	Shared Neighborhood Hits	256
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FLIP1_MOUSE
NC score	0.077598 (rank : 331)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	451	Target Neighborhood Hits	1176	Shared Neighborhood Hits	206
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_HUMAN
NC score	0.077418 (rank : 332)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	451	Target Neighborhood Hits	1405	Shared Neighborhood Hits	227
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

AKAP9_HUMAN
NC score	0.077289 (rank : 333)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	451	Target Neighborhood Hits	1710	Shared Neighborhood Hits	227
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SDCG8_MOUSE
NC score	0.077008 (rank : 334)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	451	Target Neighborhood Hits	886	Shared Neighborhood Hits	186
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

LRSM1_MOUSE
NC score	0.076193 (rank : 335)	θ value	0.365318 (rank : 241)
Query Neighborhood Hits	451	Target Neighborhood Hits	874	Shared Neighborhood Hits	201
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MKRN3_HUMAN
NC score	0.076030 (rank : 336)	θ value	5.27518 (rank : 384)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	74
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

CING_MOUSE
NC score	0.075809 (rank : 337)	θ value	4.03905 (rank : 363)
Query Neighborhood Hits	451	Target Neighborhood Hits	1432	Shared Neighborhood Hits	220
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

BIRC3_MOUSE
NC score	0.075448 (rank : 338)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	451	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

SMC1A_HUMAN
NC score	0.075337 (rank : 339)	θ value	0.0961366 (rank : 204)
Query Neighborhood Hits	451	Target Neighborhood Hits	1346	Shared Neighborhood Hits	213
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

MY18A_HUMAN
NC score	0.074970 (rank : 340)	θ value	3.0926 (rank : 348)
Query Neighborhood Hits	451	Target Neighborhood Hits	1929	Shared Neighborhood Hits	244
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

EP15_HUMAN
NC score	0.074880 (rank : 341)	θ value	0.21417 (rank : 223)
Query Neighborhood Hits	451	Target Neighborhood Hits	1021	Shared Neighborhood Hits	181
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RABE1_HUMAN
NC score	0.074547 (rank : 342)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	451	Target Neighborhood Hits	1104	Shared Neighborhood Hits	201
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
NC score	0.074520 (rank : 343)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	451	Target Neighborhood Hits	1105	Shared Neighborhood Hits	204
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

GOGA6_HUMAN
NC score	0.074455 (rank : 344)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	451	Target Neighborhood Hits	1007	Shared Neighborhood Hits	197
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

SMC1A_MOUSE
NC score	0.074347 (rank : 345)	θ value	0.0961366 (rank : 205)
Query Neighborhood Hits	451	Target Neighborhood Hits	1384	Shared Neighborhood Hits	217
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

REST_HUMAN
NC score	0.074129 (rank : 346)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	451	Target Neighborhood Hits	1605	Shared Neighborhood Hits	233
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

INCE_MOUSE
NC score	0.074091 (rank : 347)	θ value	2.36792 (rank : 327)
Query Neighborhood Hits	451	Target Neighborhood Hits	903	Shared Neighborhood Hits	174
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

TTC3_HUMAN
NC score	0.073988 (rank : 348)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	451	Target Neighborhood Hits	664	Shared Neighborhood Hits	174
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

CCD91_HUMAN
NC score	0.073976 (rank : 349)	θ value	1.38821 (rank : 302)
Query Neighborhood Hits	451	Target Neighborhood Hits	868	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CN145_MOUSE
NC score	0.073809 (rank : 350)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	451	Target Neighborhood Hits	916	Shared Neighborhood Hits	192
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CD86_MOUSE
NC score	0.073768 (rank : 351)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	451	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

GOGA1_HUMAN
NC score	0.073701 (rank : 352)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	451	Target Neighborhood Hits	1222	Shared Neighborhood Hits	204
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

EP15_MOUSE
NC score	0.073497 (rank : 353)	θ value	0.62314 (rank : 262)
Query Neighborhood Hits	451	Target Neighborhood Hits	820	Shared Neighborhood Hits	167
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MYH11_HUMAN
NC score	0.073442 (rank : 354)	θ value	0.21417 (rank : 227)
Query Neighborhood Hits	451	Target Neighborhood Hits	1806	Shared Neighborhood Hits	250
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CEP55_MOUSE
NC score	0.073419 (rank : 355)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	451	Target Neighborhood Hits	693	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

PHLB2_MOUSE
NC score	0.073398 (rank : 356)	θ value	5.27518 (rank : 392)
Query Neighborhood Hits	451	Target Neighborhood Hits	1016	Shared Neighborhood Hits	187
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

HMMR_MOUSE
NC score	0.073383 (rank : 357)	θ value	0.813845 (rank : 277)
Query Neighborhood Hits	451	Target Neighborhood Hits	1178	Shared Neighborhood Hits	207
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

RBCC1_MOUSE
NC score	0.073331 (rank : 358)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	451	Target Neighborhood Hits	1048	Shared Neighborhood Hits	196
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CASP_MOUSE
NC score	0.073297 (rank : 359)	θ value	1.81305 (rank : 314)
Query Neighborhood Hits	451	Target Neighborhood Hits	1152	Shared Neighborhood Hits	206
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

RBCC1_HUMAN
NC score	0.073260 (rank : 360)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	451	Target Neighborhood Hits	1023	Shared Neighborhood Hits	203
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CROCC_MOUSE
NC score	0.073258 (rank : 361)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	451	Target Neighborhood Hits	1460	Shared Neighborhood Hits	223
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ICOSL_MOUSE
NC score	0.073245 (rank : 362)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	451	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

CROCC_HUMAN
NC score	0.072966 (rank : 363)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	451	Target Neighborhood Hits	1409	Shared Neighborhood Hits	221
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CCD11_HUMAN
NC score	0.072898 (rank : 364)	θ value	0.62314 (rank : 259)
Query Neighborhood Hits	451	Target Neighborhood Hits	822	Shared Neighborhood Hits	179
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CASP_HUMAN
NC score	0.072795 (rank : 365)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	451	Target Neighborhood Hits	1131	Shared Neighborhood Hits	206
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SMC2_HUMAN
NC score	0.072712 (rank : 366)	θ value	0.813845 (rank : 283)
Query Neighborhood Hits	451	Target Neighborhood Hits	1405	Shared Neighborhood Hits	206
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

MYH11_MOUSE
NC score	0.072275 (rank : 367)	θ value	0.0736092 (rank : 194)
Query Neighborhood Hits	451	Target Neighborhood Hits	1777	Shared Neighborhood Hits	245
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CI093_HUMAN
NC score	0.072148 (rank : 368)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	451	Target Neighborhood Hits	1088	Shared Neighborhood Hits	202
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

UACA_HUMAN
NC score	0.072142 (rank : 369)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	451	Target Neighborhood Hits	1622	Shared Neighborhood Hits	230
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MIB2_MOUSE
NC score	0.072130 (rank : 370)	θ value	1.06291 (rank : 296)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

CNTRB_MOUSE
NC score	0.072072 (rank : 371)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	451	Target Neighborhood Hits	1029	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CTGE5_MOUSE
NC score	0.071704 (rank : 372)	θ value	0.62314 (rank : 260)
Query Neighborhood Hits	451	Target Neighborhood Hits	928	Shared Neighborhood Hits	185
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

PHLB2_HUMAN
NC score	0.071653 (rank : 373)	θ value	3.0926 (rank : 351)
Query Neighborhood Hits	451	Target Neighborhood Hits	964	Shared Neighborhood Hits	182
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

HMMR_HUMAN
NC score	0.071511 (rank : 374)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	451	Target Neighborhood Hits	1082	Shared Neighborhood Hits	194
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CEP63_HUMAN
NC score	0.071361 (rank : 375)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	451	Target Neighborhood Hits	1005	Shared Neighborhood Hits	200
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

KTN1_MOUSE
NC score	0.071071 (rank : 376)	θ value	1.38821 (rank : 304)
Query Neighborhood Hits	451	Target Neighborhood Hits	1324	Shared Neighborhood Hits	224
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

DYNA_HUMAN
NC score	0.070874 (rank : 377)	θ value	0.62314 (rank : 261)
Query Neighborhood Hits	451	Target Neighborhood Hits	1194	Shared Neighborhood Hits	204
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

CN145_HUMAN
NC score	0.070660 (rank : 378)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	451	Target Neighborhood Hits	1196	Shared Neighborhood Hits	208
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MY18A_MOUSE
NC score	0.070503 (rank : 379)	θ value	5.27518 (rank : 388)
Query Neighborhood Hits	451	Target Neighborhood Hits	1989	Shared Neighborhood Hits	232
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SYCP1_HUMAN
NC score	0.070473 (rank : 380)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	451	Target Neighborhood Hits	1313	Shared Neighborhood Hits	208
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

KTN1_HUMAN
NC score	0.070389 (rank : 381)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	451	Target Neighborhood Hits	1197	Shared Neighborhood Hits	205
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

ZSWM2_MOUSE
NC score	0.070239 (rank : 382)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	451	Target Neighborhood Hits	132	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

CNTRB_HUMAN
NC score	0.070141 (rank : 383)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ANR26_MOUSE
NC score	0.070097 (rank : 384)	θ value	0.0563607 (rank : 187)
Query Neighborhood Hits	451	Target Neighborhood Hits	1554	Shared Neighborhood Hits	222
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SWP70_MOUSE
NC score	0.070093 (rank : 385)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	451	Target Neighborhood Hits	1097	Shared Neighborhood Hits	204
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GOGA3_HUMAN
NC score	0.070089 (rank : 386)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	451	Target Neighborhood Hits	1317	Shared Neighborhood Hits	214
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

CE152_HUMAN
NC score	0.070067 (rank : 387)	θ value	1.06291 (rank : 287)
Query Neighborhood Hits	451	Target Neighborhood Hits	976	Shared Neighborhood Hits	185
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

NEST_HUMAN
NC score	0.069972 (rank : 388)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	451	Target Neighborhood Hits	1305	Shared Neighborhood Hits	180
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CING_HUMAN
NC score	0.069858 (rank : 389)	θ value	1.81305 (rank : 315)
Query Neighborhood Hits	451	Target Neighborhood Hits	1275	Shared Neighborhood Hits	207
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

MYH10_MOUSE
NC score	0.069604 (rank : 390)	θ value	3.0926 (rank : 349)
Query Neighborhood Hits	451	Target Neighborhood Hits	1612	Shared Neighborhood Hits	240
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

DESP_HUMAN
NC score	0.069439 (rank : 391)	θ value	0.0252991 (rank : 166)
Query Neighborhood Hits	451	Target Neighborhood Hits	1470	Shared Neighborhood Hits	222
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

BPAEA_MOUSE
NC score	0.069404 (rank : 392)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	451	Target Neighborhood Hits	1480	Shared Neighborhood Hits	218
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GRAP1_MOUSE
NC score	0.069280 (rank : 393)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	451	Target Neighborhood Hits	1234	Shared Neighborhood Hits	208
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

MYH10_HUMAN
NC score	0.068963 (rank : 394)	θ value	4.03905 (rank : 367)
Query Neighborhood Hits	451	Target Neighborhood Hits	1620	Shared Neighborhood Hits	244
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PDL2_HUMAN
NC score	0.068860 (rank : 395)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

RUFY2_HUMAN
NC score	0.068809 (rank : 396)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	451	Target Neighborhood Hits	1208	Shared Neighborhood Hits	192
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

EEA1_MOUSE
NC score	0.068633 (rank : 397)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	451	Target Neighborhood Hits	1637	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CK5P2_HUMAN
NC score	0.068518 (rank : 398)	θ value	0.21417 (rank : 221)
Query Neighborhood Hits	451	Target Neighborhood Hits	1433	Shared Neighborhood Hits	208
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MYH9_MOUSE
NC score	0.068383 (rank : 399)	θ value	0.813845 (rank : 279)
Query Neighborhood Hits	451	Target Neighborhood Hits	1829	Shared Neighborhood Hits	245
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RAD50_HUMAN
NC score	0.068350 (rank : 400)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	451	Target Neighborhood Hits	1317	Shared Neighborhood Hits	211
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

REST_MOUSE
NC score	0.068220 (rank : 401)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	451	Target Neighborhood Hits	1506	Shared Neighborhood Hits	220
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

DYNA_MOUSE
NC score	0.068038 (rank : 402)	θ value	0.365318 (rank : 238)
Query Neighborhood Hits	451	Target Neighborhood Hits	1084	Shared Neighborhood Hits	189
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

GOGA3_MOUSE
NC score	0.067883 (rank : 403)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	451	Target Neighborhood Hits	1437	Shared Neighborhood Hits	226
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

RN122_HUMAN
NC score	0.067766 (rank : 404)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

CYLN2_MOUSE
NC score	0.067760 (rank : 405)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	451	Target Neighborhood Hits	1002	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

SIAH2_HUMAN
NC score	0.067750 (rank : 406)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	451	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
NC score	0.067557 (rank : 407)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	55
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

PIBF1_HUMAN
NC score	0.067534 (rank : 408)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	451	Target Neighborhood Hits	1041	Shared Neighborhood Hits	195
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CALD1_HUMAN
NC score	0.067503 (rank : 409)	θ value	4.03905 (rank : 361)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	173
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CYTSA_HUMAN
NC score	0.067094 (rank : 410)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	451	Target Neighborhood Hits	1138	Shared Neighborhood Hits	203
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

MYH9_HUMAN
NC score	0.067046 (rank : 411)	θ value	0.47712 (rank : 252)
Query Neighborhood Hits	451	Target Neighborhood Hits	1762	Shared Neighborhood Hits	247
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CUTL1_HUMAN
NC score	0.066841 (rank : 412)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	451	Target Neighborhood Hits	1574	Shared Neighborhood Hits	211
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

RAD50_MOUSE
NC score	0.066770 (rank : 413)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	451	Target Neighborhood Hits	1366	Shared Neighborhood Hits	215
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CAF1A_MOUSE
NC score	0.066583 (rank : 414)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	451	Target Neighborhood Hits	736	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

RN126_MOUSE
NC score	0.066485 (rank : 415)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

PEPL_HUMAN
NC score	0.066435 (rank : 416)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	451	Target Neighborhood Hits	1141	Shared Neighborhood Hits	195
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CCD27_HUMAN
NC score	0.066384 (rank : 417)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	451	Target Neighborhood Hits	594	Shared Neighborhood Hits	151
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

RB6I2_HUMAN
NC score	0.066367 (rank : 418)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	451	Target Neighborhood Hits	1584	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

ZN364_HUMAN
NC score	0.066289 (rank : 419)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

IFT81_HUMAN
NC score	0.066262 (rank : 420)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	451	Target Neighborhood Hits	893	Shared Neighborhood Hits	189
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GOGA5_MOUSE
NC score	0.066242 (rank : 421)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	451	Target Neighborhood Hits	1434	Shared Neighborhood Hits	211
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

RFIP3_HUMAN
NC score	0.066116 (rank : 422)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	451	Target Neighborhood Hits	1055	Shared Neighborhood Hits	183
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

MD1L1_MOUSE
NC score	0.066028 (rank : 423)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	451	Target Neighborhood Hits	1001	Shared Neighborhood Hits	193
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

SM1L2_HUMAN
NC score	0.065960 (rank : 424)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	451	Target Neighborhood Hits	1019	Shared Neighborhood Hits	191
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

GOGA1_MOUSE
NC score	0.065893 (rank : 425)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	451	Target Neighborhood Hits	994	Shared Neighborhood Hits	181
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

LRC45_MOUSE
NC score	0.065789 (rank : 426)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	177
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CYTSA_MOUSE
NC score	0.065347 (rank : 427)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	451	Target Neighborhood Hits	1104	Shared Neighborhood Hits	205
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

OPTN_MOUSE
NC score	0.065304 (rank : 428)	θ value	1.81305 (rank : 317)
Query Neighborhood Hits	451	Target Neighborhood Hits	1120	Shared Neighborhood Hits	188
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RNF19_MOUSE
NC score	0.065189 (rank : 429)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	451	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

MD1L1_HUMAN
NC score	0.065096 (rank : 430)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	451	Target Neighborhood Hits	893	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

TMF1_HUMAN
NC score	0.065052 (rank : 431)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	451	Target Neighborhood Hits	987	Shared Neighborhood Hits	185
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

MKRN1_HUMAN
NC score	0.064986 (rank : 432)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	451	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

RNF19_HUMAN
NC score	0.064902 (rank : 433)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

PDL2_MOUSE
NC score	0.064823 (rank : 434)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	451	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

CUTL1_MOUSE
NC score	0.064764 (rank : 435)	θ value	0.813845 (rank : 275)
Query Neighborhood Hits	451	Target Neighborhood Hits	1620	Shared Neighborhood Hits	205
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

MYH8_MOUSE
NC score	0.064613 (rank : 436)	θ value	2.36792 (rank : 331)
Query Neighborhood Hits	451	Target Neighborhood Hits	1600	Shared Neighborhood Hits	234
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SMC3_HUMAN
NC score	0.064593 (rank : 437)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	451	Target Neighborhood Hits	1186	Shared Neighborhood Hits	198
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

MYH8_HUMAN
NC score	0.064534 (rank : 438)	θ value	5.27518 (rank : 390)
Query Neighborhood Hits	451	Target Neighborhood Hits	1610	Shared Neighborhood Hits	229
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SMC3_MOUSE
NC score	0.064494 (rank : 439)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	451	Target Neighborhood Hits	1187	Shared Neighborhood Hits	198
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

CI039_HUMAN
NC score	0.064109 (rank : 440)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	451	Target Neighborhood Hits	1171	Shared Neighborhood Hits	198
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

RB6I2_MOUSE
NC score	0.064094 (rank : 441)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	451	Target Neighborhood Hits	1433	Shared Neighborhood Hits	218
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

PLEC1_HUMAN
NC score	0.064090 (rank : 442)	θ value	5.27518 (rank : 393)
Query Neighborhood Hits	451	Target Neighborhood Hits	1326	Shared Neighborhood Hits	210
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MKRN1_MOUSE
NC score	0.064041 (rank : 443)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	451	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

IFT74_MOUSE
NC score	0.063709 (rank : 444)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	451	Target Neighborhood Hits	939	Shared Neighborhood Hits	192
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

GOGA2_MOUSE
NC score	0.063660 (rank : 445)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	451	Target Neighborhood Hits	944	Shared Neighborhood Hits	185
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CYLN2_HUMAN
NC score	0.063504 (rank : 446)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	451	Target Neighborhood Hits	1004	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

NDE1_HUMAN
NC score	0.063413 (rank : 447)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	451	Target Neighborhood Hits	823	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

K0555_HUMAN
NC score	0.063340 (rank : 448)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	451	Target Neighborhood Hits	880	Shared Neighborhood Hits	170
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

SM1L2_MOUSE
NC score	0.063328 (rank : 449)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	451	Target Neighborhood Hits	918	Shared Neighborhood Hits	191
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

IF3A_HUMAN
NC score	0.063324 (rank : 450)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	451	Target Neighborhood Hits	875	Shared Neighborhood Hits	179
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

PDL1_HUMAN
NC score	0.063312 (rank : 451)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

CCD11_MOUSE
NC score	0.063257 (rank : 452)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	135
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

IF3A_MOUSE
NC score	0.063233 (rank : 453)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	451	Target Neighborhood Hits	871	Shared Neighborhood Hits	176
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

FYCO1_HUMAN
NC score	0.063211 (rank : 454)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	451	Target Neighborhood Hits	1149	Shared Neighborhood Hits	194
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

SYNE1_HUMAN
NC score	0.063152 (rank : 455)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	451	Target Neighborhood Hits	1484	Shared Neighborhood Hits	219
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

NAF1_MOUSE
NC score	0.063066 (rank : 456)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	451	Target Neighborhood Hits	852	Shared Neighborhood Hits	183
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

SMC2_MOUSE
NC score	0.063064 (rank : 457)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	451	Target Neighborhood Hits	1131	Shared Neighborhood Hits	197
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MYH14_MOUSE
NC score	0.063037 (rank : 458)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	451	Target Neighborhood Hits	1225	Shared Neighborhood Hits	213
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

EVPL_MOUSE
NC score	0.063023 (rank : 459)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	451	Target Neighborhood Hits	952	Shared Neighborhood Hits	181
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

MKRN3_MOUSE
NC score	0.062732 (rank : 460)	θ value	2.36792 (rank : 329)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	57
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

CJ118_MOUSE
NC score	0.062705 (rank : 461)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	451	Target Neighborhood Hits	1132	Shared Neighborhood Hits	194
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

BICD2_HUMAN
NC score	0.062315 (rank : 462)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	188
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

EVPL_HUMAN
NC score	0.062212 (rank : 463)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	451	Target Neighborhood Hits	895	Shared Neighborhood Hits	181
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

RN167_MOUSE
NC score	0.062209 (rank : 464)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

T3JAM_MOUSE
NC score	0.062106 (rank : 465)	θ value	0.47712 (rank : 256)
Query Neighborhood Hits	451	Target Neighborhood Hits	535	Shared Neighborhood Hits	135
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

BICD2_MOUSE
NC score	0.062062 (rank : 466)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	451	Target Neighborhood Hits	864	Shared Neighborhood Hits	188
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

DZIP3_MOUSE
NC score	0.062013 (rank : 467)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	451	Target Neighborhood Hits	414	Shared Neighborhood Hits	149
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ARI2_HUMAN
NC score	0.061918 (rank : 468)	θ value	1.81305 (rank : 312)
Query Neighborhood Hits	451	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

LRC45_HUMAN
NC score	0.061905 (rank : 469)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	451	Target Neighborhood Hits	933	Shared Neighborhood Hits	180
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CP135_HUMAN
NC score	0.061777 (rank : 470)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	451	Target Neighborhood Hits	1290	Shared Neighborhood Hits	203
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SWP70_HUMAN
NC score	0.061752 (rank : 471)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	451	Target Neighborhood Hits	973	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MYH1_HUMAN
NC score	0.061592 (rank : 472)	θ value	6.88961 (rank : 411)
Query Neighborhood Hits	451	Target Neighborhood Hits	1478	Shared Neighborhood Hits	225
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

HAP1_HUMAN
NC score	0.061499 (rank : 473)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	451	Target Neighborhood Hits	606	Shared Neighborhood Hits	154
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

SYCP3_HUMAN
NC score	0.061385 (rank : 474)	θ value	1.38821 (rank : 308)
Query Neighborhood Hits	451	Target Neighborhood Hits	276	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

CCD39_HUMAN
NC score	0.061330 (rank : 475)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	451	Target Neighborhood Hits	868	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

NEMO_MOUSE
NC score	0.061267 (rank : 476)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	451	Target Neighborhood Hits	658	Shared Neighborhood Hits	165
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

IFT74_HUMAN
NC score	0.061234 (rank : 477)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	451	Target Neighborhood Hits	949	Shared Neighborhood Hits	179
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

MYH2_HUMAN
NC score	0.061195 (rank : 478)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	451	Target Neighborhood Hits	1491	Shared Neighborhood Hits	224
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

RN122_MOUSE
NC score	0.061123 (rank : 479)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

MYH3_HUMAN
NC score	0.061038 (rank : 480)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	451	Target Neighborhood Hits	1660	Shared Neighborhood Hits	234
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

XE7_HUMAN
NC score	0.061023 (rank : 481)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	451	Target Neighborhood Hits	738	Shared Neighborhood Hits	159
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

CCD39_MOUSE
NC score	0.060915 (rank : 482)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	451	Target Neighborhood Hits	1026	Shared Neighborhood Hits	190
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

RFIP4_MOUSE
NC score	0.060897 (rank : 483)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	451	Target Neighborhood Hits	708	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CT096_HUMAN
NC score	0.060851 (rank : 484)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

MYH1_MOUSE
NC score	0.060809 (rank : 485)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	451	Target Neighborhood Hits	1461	Shared Neighborhood Hits	222
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
NC score	0.060728 (rank : 486)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	451	Target Neighborhood Hits	1476	Shared Neighborhood Hits	227
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

PEPL_MOUSE
NC score	0.060586 (rank : 487)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	451	Target Neighborhood Hits	1105	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

LIPA2_MOUSE
NC score	0.060578 (rank : 488)	θ value	2.36792 (rank : 328)
Query Neighborhood Hits	451	Target Neighborhood Hits	1282	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

GRAP1_HUMAN
NC score	0.060411 (rank : 489)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	451	Target Neighborhood Hits	944	Shared Neighborhood Hits	185
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GOGA5_HUMAN
NC score	0.060344 (rank : 490)	θ value	0.62314 (rank : 263)
Query Neighborhood Hits	451	Target Neighborhood Hits	1168	Shared Neighborhood Hits	192
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

PEX2_HUMAN
NC score	0.060303 (rank : 491)	θ value	5.27518 (rank : 391)
Query Neighborhood Hits	451	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

CP135_MOUSE
NC score	0.060035 (rank : 492)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	451	Target Neighborhood Hits	1278	Shared Neighborhood Hits	211
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CCHCR_HUMAN
NC score	0.060022 (rank : 493)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	451	Target Neighborhood Hits	717	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

MYH4_HUMAN
NC score	0.059840 (rank : 494)	θ value	5.27518 (rank : 389)
Query Neighborhood Hits	451	Target Neighborhood Hits	1377	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH6_MOUSE
NC score	0.059776 (rank : 495)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	451	Target Neighborhood Hits	1501	Shared Neighborhood Hits	226
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

LIPA1_HUMAN
NC score	0.059764 (rank : 496)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	451	Target Neighborhood Hits	1294	Shared Neighborhood Hits	204
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

RFIP4_HUMAN
NC score	0.059730 (rank : 497)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	451	Target Neighborhood Hits	785	Shared Neighborhood Hits	171
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CJ118_HUMAN
NC score	0.059685 (rank : 498)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	180
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

GAS8_HUMAN
NC score	0.059443 (rank : 499)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	451	Target Neighborhood Hits	819	Shared Neighborhood Hits	182
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

ARI2_MOUSE
NC score	0.059396 (rank : 500)	θ value	2.36792 (rank : 322)
Query Neighborhood Hits	451	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

LIPA2_HUMAN
NC score	0.059314 (rank : 501)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	451	Target Neighborhood Hits	1044	Shared Neighborhood Hits	186
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

GOGA2_HUMAN
NC score	0.059141 (rank : 502)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	166
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

SPAG5_MOUSE
NC score	0.059106 (rank : 503)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	451	Target Neighborhood Hits	612	Shared Neighborhood Hits	149
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

CCD91_MOUSE
NC score	0.059029 (rank : 504)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	451	Target Neighborhood Hits	699	Shared Neighborhood Hits	155
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CTGE5_HUMAN
NC score	0.058912 (rank : 505)	θ value	4.03905 (rank : 364)
Query Neighborhood Hits	451	Target Neighborhood Hits	800	Shared Neighborhood Hits	171
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

ZN364_MOUSE
NC score	0.058871 (rank : 506)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

CENPJ_HUMAN
NC score	0.058842 (rank : 507)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	451	Target Neighborhood Hits	721	Shared Neighborhood Hits	157
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

TEX9_MOUSE
NC score	0.058813 (rank : 508)	θ value	1.81305 (rank : 319)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

CCD21_MOUSE
NC score	0.058716 (rank : 509)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	190
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

HIP1R_HUMAN
NC score	0.058633 (rank : 510)	θ value	4.03905 (rank : 366)
Query Neighborhood Hits	451	Target Neighborhood Hits	809	Shared Neighborhood Hits	175
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

CCD96_MOUSE
NC score	0.058434 (rank : 511)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	451	Target Neighborhood Hits	704	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

RN126_HUMAN
NC score	0.058375 (rank : 512)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	451	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

IFT81_MOUSE
NC score	0.058323 (rank : 513)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	185
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MYO5C_HUMAN
NC score	0.058115 (rank : 514)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	451	Target Neighborhood Hits	1206	Shared Neighborhood Hits	212
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

OFD1_HUMAN
NC score	0.058036 (rank : 515)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	451	Target Neighborhood Hits	753	Shared Neighborhood Hits	167
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

CCD21_HUMAN
NC score	0.057923 (rank : 516)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	451	Target Neighborhood Hits	1228	Shared Neighborhood Hits	201
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

BICD1_MOUSE
NC score	0.057861 (rank : 517)	θ value	0.0961366 (rank : 200)
Query Neighborhood Hits	451	Target Neighborhood Hits	837	Shared Neighborhood Hits	182
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCHCR_MOUSE
NC score	0.057777 (rank : 518)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	451	Target Neighborhood Hits	932	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

AMOL2_MOUSE
NC score	0.057720 (rank : 519)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	451	Target Neighborhood Hits	591	Shared Neighborhood Hits	150
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

FYCO1_MOUSE
NC score	0.057666 (rank : 520)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	451	Target Neighborhood Hits	1059	Shared Neighborhood Hits	184
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

NAF1_HUMAN
NC score	0.057631 (rank : 521)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	180
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

MYH13_HUMAN
NC score	0.057622 (rank : 522)	θ value	2.36792 (rank : 330)
Query Neighborhood Hits	451	Target Neighborhood Hits	1504	Shared Neighborhood Hits	224
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH7_HUMAN
NC score	0.057610 (rank : 523)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	451	Target Neighborhood Hits	1559	Shared Neighborhood Hits	223
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

ERC2_HUMAN
NC score	0.057597 (rank : 524)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	451	Target Neighborhood Hits	1156	Shared Neighborhood Hits	195
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

RIMB1_MOUSE
NC score	0.057491 (rank : 525)	θ value	3.0926 (rank : 352)
Query Neighborhood Hits	451	Target Neighborhood Hits	1376	Shared Neighborhood Hits	187
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ERC2_MOUSE
NC score	0.057430 (rank : 526)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	451	Target Neighborhood Hits	1166	Shared Neighborhood Hits	195
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

HOOK1_HUMAN
NC score	0.057423 (rank : 527)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	451	Target Neighborhood Hits	942	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

RN167_HUMAN
NC score	0.057348 (rank : 528)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

SAS6_MOUSE
NC score	0.057340 (rank : 529)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	451	Target Neighborhood Hits	931	Shared Neighborhood Hits	174
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SPAG5_HUMAN
NC score	0.057228 (rank : 530)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	451	Target Neighborhood Hits	625	Shared Neighborhood Hits	158
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

MYH6_HUMAN
NC score	0.057171 (rank : 531)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	451	Target Neighborhood Hits	1426	Shared Neighborhood Hits	221
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RN165_HUMAN
NC score	0.056995 (rank : 532)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

SYNE2_HUMAN
NC score	0.056988 (rank : 533)	θ value	6.88961 (rank : 417)
Query Neighborhood Hits	451	Target Neighborhood Hits	1323	Shared Neighborhood Hits	203
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TUFT1_MOUSE
NC score	0.056832 (rank : 534)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	451	Target Neighborhood Hits	732	Shared Neighborhood Hits	165
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

GAS8_MOUSE
NC score	0.056829 (rank : 535)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	451	Target Neighborhood Hits	622	Shared Neighborhood Hits	156
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

BICD1_HUMAN
NC score	0.056659 (rank : 536)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	451	Target Neighborhood Hits	844	Shared Neighborhood Hits	177
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BPAEA_HUMAN
NC score	0.056502 (rank : 537)	θ value	1.81305 (rank : 313)
Query Neighborhood Hits	451	Target Neighborhood Hits	1369	Shared Neighborhood Hits	203
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

UACA_MOUSE
NC score	0.056430 (rank : 538)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	451	Target Neighborhood Hits	1620	Shared Neighborhood Hits	227
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

HOME2_MOUSE
NC score	0.056404 (rank : 539)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	451	Target Neighborhood Hits	882	Shared Neighborhood Hits	179
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

CF152_MOUSE
NC score	0.056374 (rank : 540)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	451	Target Neighborhood Hits	597	Shared Neighborhood Hits	143
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

ZN291_HUMAN
NC score	0.056309 (rank : 541)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	451	Target Neighborhood Hits	647	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

DZIP3_HUMAN
NC score	0.056284 (rank : 542)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	451	Target Neighborhood Hits	399	Shared Neighborhood Hits	144
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

HOOK1_MOUSE
NC score	0.056282 (rank : 543)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	451	Target Neighborhood Hits	910	Shared Neighborhood Hits	180
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

C102B_HUMAN
NC score	0.056125 (rank : 544)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	451	Target Neighborhood Hits	542	Shared Neighborhood Hits	137
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

RNF17_MOUSE
NC score	0.056045 (rank : 545)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

SMC4_MOUSE
NC score	0.055969 (rank : 546)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	451	Target Neighborhood Hits	830	Shared Neighborhood Hits	168
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TNIP3_HUMAN
NC score	0.055822 (rank : 547)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	451	Target Neighborhood Hits	511	Shared Neighborhood Hits	140
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

IF2P_HUMAN
NC score	0.055809 (rank : 548)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	451	Target Neighborhood Hits	889	Shared Neighborhood Hits	145
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IDLC_HUMAN
NC score	0.055803 (rank : 549)	θ value	0.21417 (rank : 224)
Query Neighborhood Hits	451	Target Neighborhood Hits	348	Shared Neighborhood Hits	107
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

NEMO_HUMAN
NC score	0.055788 (rank : 550)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	451	Target Neighborhood Hits	820	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

HOOK3_HUMAN
NC score	0.055735 (rank : 551)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	451	Target Neighborhood Hits	1070	Shared Neighborhood Hits	194
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

TPM4_MOUSE
NC score	0.055511 (rank : 552)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	451	Target Neighborhood Hits	703	Shared Neighborhood Hits	166
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

KMHN1_HUMAN
NC score	0.055494 (rank : 553)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	451	Target Neighborhood Hits	950	Shared Neighborhood Hits	180
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

STXB4_HUMAN
NC score	0.055345 (rank : 554)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	451	Target Neighborhood Hits	616	Shared Neighborhood Hits	141
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MYH14_HUMAN
NC score	0.055170 (rank : 555)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	451	Target Neighborhood Hits	995	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

HOOK3_MOUSE
NC score	0.054966 (rank : 556)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	451	Target Neighborhood Hits	1007	Shared Neighborhood Hits	187
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

SMC4_HUMAN
NC score	0.054946 (rank : 557)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

CARD9_HUMAN
NC score	0.054923 (rank : 558)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	451	Target Neighborhood Hits	602	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CA065_HUMAN
NC score	0.054780 (rank : 559)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	451	Target Neighborhood Hits	469	Shared Neighborhood Hits	129
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

IDLC_MOUSE
NC score	0.054679 (rank : 560)	θ value	0.163984 (rank : 216)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

TACC2_HUMAN
NC score	0.054589 (rank : 561)	θ value	6.88961 (rank : 418)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	157
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TPM2_HUMAN
NC score	0.054355 (rank : 562)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	451	Target Neighborhood Hits	677	Shared Neighborhood Hits	152
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

RRBP1_HUMAN
NC score	0.054256 (rank : 563)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	451	Target Neighborhood Hits	1306	Shared Neighborhood Hits	191
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RABE2_MOUSE
NC score	0.054146 (rank : 564)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	451	Target Neighborhood Hits	598	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

KMHN1_MOUSE
NC score	0.053961 (rank : 565)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	451	Target Neighborhood Hits	949	Shared Neighborhood Hits	170
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

CTTB2_HUMAN
NC score	0.053958 (rank : 566)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	451	Target Neighborhood Hits	1061	Shared Neighborhood Hits	186
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

LIPA3_HUMAN
NC score	0.053953 (rank : 567)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	451	Target Neighborhood Hits	828	Shared Neighborhood Hits	175
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

INVO_HUMAN
NC score	0.053929 (rank : 568)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	451	Target Neighborhood Hits	636	Shared Neighborhood Hits	138
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CEP55_HUMAN
NC score	0.053805 (rank : 569)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	138
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

MACF1_HUMAN
NC score	0.053617 (rank : 570)	θ value	5.27518 (rank : 382)
Query Neighborhood Hits	451	Target Neighborhood Hits	1341	Shared Neighborhood Hits	196
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

CK5P2_MOUSE
NC score	0.053560 (rank : 571)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	451	Target Neighborhood Hits	1151	Shared Neighborhood Hits	182
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

TAXB1_HUMAN
NC score	0.053521 (rank : 572)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	451	Target Neighborhood Hits	829	Shared Neighborhood Hits	165
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

CCDC6_HUMAN
NC score	0.053516 (rank : 573)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	451	Target Neighborhood Hits	723	Shared Neighborhood Hits	161
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

TSC1_HUMAN
NC score	0.053495 (rank : 574)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	451	Target Neighborhood Hits	765	Shared Neighborhood Hits	163
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

MY18B_HUMAN
NC score	0.053490 (rank : 575)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	451	Target Neighborhood Hits	1299	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

KINH_HUMAN
NC score	0.053458 (rank : 576)	θ value	0.813845 (rank : 278)
Query Neighborhood Hits	451	Target Neighborhood Hits	1231	Shared Neighborhood Hits	197
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CCD45_HUMAN
NC score	0.053443 (rank : 577)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	451	Target Neighborhood Hits	525	Shared Neighborhood Hits	131
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

GOG8A_HUMAN
NC score	0.053432 (rank : 578)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	451	Target Neighborhood Hits	635	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

KNTC2_HUMAN
NC score	0.053339 (rank : 579)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	451	Target Neighborhood Hits	673	Shared Neighborhood Hits	160
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

TPM3_MOUSE
NC score	0.053202 (rank : 580)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	451	Target Neighborhood Hits	676	Shared Neighborhood Hits	152
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

CAF1A_HUMAN
NC score	0.053148 (rank : 581)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	451	Target Neighborhood Hits	750	Shared Neighborhood Hits	148
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

NEB2_MOUSE
NC score	0.053124 (rank : 582)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	451	Target Neighborhood Hits	889	Shared Neighborhood Hits	173
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

MACF1_MOUSE
NC score	0.053079 (rank : 583)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	451	Target Neighborhood Hits	1313	Shared Neighborhood Hits	198
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

TPM2_MOUSE
NC score	0.053065 (rank : 584)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	451	Target Neighborhood Hits	676	Shared Neighborhood Hits	153
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

HIP1R_MOUSE
NC score	0.053019 (rank : 585)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	451	Target Neighborhood Hits	959	Shared Neighborhood Hits	175
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

CCD13_HUMAN
NC score	0.052975 (rank : 586)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	451	Target Neighborhood Hits	721	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

KNTC2_MOUSE
NC score	0.052970 (rank : 587)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	451	Target Neighborhood Hits	692	Shared Neighborhood Hits	162
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

CCD62_HUMAN
NC score	0.052926 (rank : 588)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	451	Target Neighborhood Hits	631	Shared Neighborhood Hits	150
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

TUFT1_HUMAN
NC score	0.052719 (rank : 589)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	451	Target Neighborhood Hits	686	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

NEB2_HUMAN
NC score	0.052701 (rank : 590)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	451	Target Neighborhood Hits	883	Shared Neighborhood Hits	174
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

TPM3_HUMAN
NC score	0.052646 (rank : 591)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	451	Target Neighborhood Hits	689	Shared Neighborhood Hits	154
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

RUFY1_HUMAN
NC score	0.052488 (rank : 592)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	451	Target Neighborhood Hits	848	Shared Neighborhood Hits	182
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SAS6_HUMAN
NC score	0.052483 (rank : 593)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	451	Target Neighborhood Hits	791	Shared Neighborhood Hits	166
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

NUF2_MOUSE
NC score	0.052436 (rank : 594)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	451	Target Neighborhood Hits	585	Shared Neighborhood Hits	149
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

LUZP1_MOUSE
NC score	0.052429 (rank : 595)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	451	Target Neighborhood Hits	940	Shared Neighborhood Hits	159
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

GCP60_HUMAN
NC score	0.052367 (rank : 596)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	451	Target Neighborhood Hits	419	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

TAXB1_MOUSE
NC score	0.052355 (rank : 597)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	451	Target Neighborhood Hits	886	Shared Neighborhood Hits	166
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

CAR11_HUMAN
NC score	0.052327 (rank : 598)	θ value	0.21417 (rank : 220)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

AN30A_HUMAN
NC score	0.052266 (rank : 599)	θ value	1.81305 (rank : 311)
Query Neighborhood Hits	451	Target Neighborhood Hits	1119	Shared Neighborhood Hits	179
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ZC313_HUMAN
NC score	0.052260 (rank : 600)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	126
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

RNF13_HUMAN
NC score	0.052236 (rank : 601)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	56
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

KINH_MOUSE
NC score	0.052184 (rank : 602)	θ value	1.06291 (rank : 293)
Query Neighborhood Hits	451	Target Neighborhood Hits	1082	Shared Neighborhood Hits	194
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

PHLB1_HUMAN
NC score	0.052118 (rank : 603)	θ value	0.47712 (rank : 254)
Query Neighborhood Hits	451	Target Neighborhood Hits	1038	Shared Neighborhood Hits	161
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

NUF2_HUMAN
NC score	0.052041 (rank : 604)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	451	Target Neighborhood Hits	661	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

LRRF2_HUMAN
NC score	0.051921 (rank : 605)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	451	Target Neighborhood Hits	791	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

CT116_HUMAN
NC score	0.051900 (rank : 606)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	89
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

BPA1_MOUSE
NC score	0.051782 (rank : 607)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	451	Target Neighborhood Hits	1477	Shared Neighborhood Hits	202
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CKAP4_MOUSE
NC score	0.051588 (rank : 608)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	451	Target Neighborhood Hits	596	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

AMOL2_HUMAN
NC score	0.051538 (rank : 609)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	451	Target Neighborhood Hits	603	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

MYO5A_MOUSE
NC score	0.051534 (rank : 610)	θ value	0.62314 (rank : 265)
Query Neighborhood Hits	451	Target Neighborhood Hits	1117	Shared Neighborhood Hits	198
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

CCD45_MOUSE
NC score	0.051500 (rank : 611)	θ value	2.36792 (rank : 323)
Query Neighborhood Hits	451	Target Neighborhood Hits	663	Shared Neighborhood Hits	144
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

RAI14_MOUSE
NC score	0.051477 (rank : 612)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	451	Target Neighborhood Hits	1505	Shared Neighborhood Hits	203
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ADIP_HUMAN
NC score	0.051474 (rank : 613)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	451	Target Neighborhood Hits	470	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

HOOK2_HUMAN
NC score	0.051348 (rank : 614)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	451	Target Neighborhood Hits	714	Shared Neighborhood Hits	161
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

TPM1_MOUSE
NC score	0.051225 (rank : 615)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	451	Target Neighborhood Hits	729	Shared Neighborhood Hits	163
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

CR034_HUMAN
NC score	0.051117 (rank : 616)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	451	Target Neighborhood Hits	538	Shared Neighborhood Hits	145
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

TACC1_HUMAN
NC score	0.051075 (rank : 617)	θ value	3.0926 (rank : 358)
Query Neighborhood Hits	451	Target Neighborhood Hits	597	Shared Neighborhood Hits	138
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

KIF5C_MOUSE
NC score	0.051014 (rank : 618)	θ value	0.279714 (rank : 234)
Query Neighborhood Hits	451	Target Neighborhood Hits	1040	Shared Neighborhood Hits	191
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

HIP1_HUMAN
NC score	0.050949 (rank : 619)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	451	Target Neighborhood Hits	1016	Shared Neighborhood Hits	182
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

PHLB3_HUMAN
NC score	0.050724 (rank : 620)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	451	Target Neighborhood Hits	304	Shared Neighborhood Hits	99
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

RNF13_MOUSE
NC score	0.050700 (rank : 621)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	451	Target Neighborhood Hits	164	Shared Neighborhood Hits	65
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TEX9_HUMAN
NC score	0.050645 (rank : 622)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	451	Target Neighborhood Hits	541	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

CEP70_MOUSE
NC score	0.050556 (rank : 623)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	451	Target Neighborhood Hits	532	Shared Neighborhood Hits	140
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CEP57_MOUSE
NC score	0.050499 (rank : 624)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	451	Target Neighborhood Hits	580	Shared Neighborhood Hits	153
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

RUFY2_MOUSE
NC score	0.050364 (rank : 625)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	451	Target Neighborhood Hits	820	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RRBP1_MOUSE
NC score	0.050361 (rank : 626)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	451	Target Neighborhood Hits	1650	Shared Neighborhood Hits	204
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

MACF4_HUMAN
NC score	0.050299 (rank : 627)	θ value	5.27518 (rank : 383)
Query Neighborhood Hits	451	Target Neighborhood Hits	1321	Shared Neighborhood Hits	194
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

HOOK2_MOUSE
NC score	0.050284 (rank : 628)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	451	Target Neighborhood Hits	736	Shared Neighborhood Hits	168
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

CKAP4_HUMAN
NC score	0.050245 (rank : 629)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	451	Target Neighborhood Hits	592	Shared Neighborhood Hits	134
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MYLIP_HUMAN
NC score	0.050169 (rank : 630)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	451	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

AL2SB_HUMAN
NC score	0.050150 (rank : 631)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	106
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

TACC3_MOUSE
NC score	0.050115 (rank : 632)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	451	Target Neighborhood Hits	607	Shared Neighborhood Hits	140
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TPM1_HUMAN
NC score	0.050078 (rank : 633)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	451	Target Neighborhood Hits	716	Shared Neighborhood Hits	162
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

OPTN_HUMAN
NC score	0.050074 (rank : 634)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	451	Target Neighborhood Hits	827	Shared Neighborhood Hits	159
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

TACC2_MOUSE
NC score	0.049704 (rank : 635)	θ value	4.03905 (rank : 369)
Query Neighborhood Hits	451	Target Neighborhood Hits	774	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

KIF5C_HUMAN
NC score	0.048834 (rank : 636)	θ value	1.38821 (rank : 303)
Query Neighborhood Hits	451	Target Neighborhood Hits	974	Shared Neighborhood Hits	183
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MYO5A_HUMAN
NC score	0.048738 (rank : 637)	θ value	1.38821 (rank : 305)
Query Neighborhood Hits	451	Target Neighborhood Hits	1092	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

KIF4A_MOUSE
NC score	0.047643 (rank : 638)	θ value	1.06291 (rank : 292)
Query Neighborhood Hits	451	Target Neighborhood Hits	1033	Shared Neighborhood Hits	190
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KIF4A_HUMAN
NC score	0.047491 (rank : 639)	θ value	3.0926 (rank : 345)
Query Neighborhood Hits	451	Target Neighborhood Hits	1159	Shared Neighborhood Hits	199
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

ITSN1_MOUSE
NC score	0.047161 (rank : 640)	θ value	0.62314 (rank : 264)
Query Neighborhood Hits	451	Target Neighborhood Hits	1669	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
NC score	0.046699 (rank : 641)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	451	Target Neighborhood Hits	1371	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MYO6_HUMAN
NC score	0.046634 (rank : 642)	θ value	0.21417 (rank : 228)
Query Neighborhood Hits	451	Target Neighborhood Hits	727	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

ENKUR_HUMAN
NC score	0.046311 (rank : 643)	θ value	0.21417 (rank : 222)
Query Neighborhood Hits	451	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

HC127_HUMAN
NC score	0.046180 (rank : 644)	θ value	0.365318 (rank : 239)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.046180 (rank : 645)	θ value	0.365318 (rank : 240)
Query Neighborhood Hits	451	Target Neighborhood Hits	292	Shared Neighborhood Hits	88
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

U2AFM_HUMAN
NC score	0.044920 (rank : 646)	θ value	2.36792 (rank : 337)
Query Neighborhood Hits	451	Target Neighborhood Hits	577	Shared Neighborhood Hits	138
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

MYO6_MOUSE
NC score	0.043770 (rank : 647)	θ value	0.279714 (rank : 235)
Query Neighborhood Hits	451	Target Neighborhood Hits	586	Shared Neighborhood Hits	151
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

ENAH_HUMAN
NC score	0.043421 (rank : 648)	θ value	2.36792 (rank : 325)
Query Neighborhood Hits	451	Target Neighborhood Hits	784	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

MOES_MOUSE
NC score	0.042338 (rank : 649)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	451	Target Neighborhood Hits	923	Shared Neighborhood Hits	176
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
NC score	0.041703 (rank : 650)	θ value	5.27518 (rank : 387)
Query Neighborhood Hits	451	Target Neighborhood Hits	892	Shared Neighborhood Hits	176
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

UTRO_HUMAN
NC score	0.040682 (rank : 651)	θ value	5.27518 (rank : 396)
Query Neighborhood Hits	451	Target Neighborhood Hits	960	Shared Neighborhood Hits	171
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

ITSN2_HUMAN
NC score	0.038260 (rank : 652)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	451	Target Neighborhood Hits	1173	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

LMNB2_MOUSE
NC score	0.038109 (rank : 653)	θ value	0.00175202 (rank : 136)
Query Neighborhood Hits	451	Target Neighborhood Hits	674	Shared Neighborhood Hits	150
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

PHLB1_MOUSE
NC score	0.037749 (rank : 654)	θ value	6.88961 (rank : 413)
Query Neighborhood Hits	451	Target Neighborhood Hits	678	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

BSN_HUMAN
NC score	0.037363 (rank : 655)	θ value	0.47712 (rank : 246)
Query Neighborhood Hits	451	Target Neighborhood Hits	1537	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PLCB3_HUMAN
NC score	0.036753 (rank : 656)	θ value	1.38821 (rank : 306)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	108
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

NGAP_HUMAN
NC score	0.036558 (rank : 657)	θ value	1.06291 (rank : 297)
Query Neighborhood Hits	451	Target Neighborhood Hits	517	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

MORC3_HUMAN
NC score	0.035353 (rank : 658)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	451	Target Neighborhood Hits	489	Shared Neighborhood Hits	118
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

KIFC1_HUMAN
NC score	0.034379 (rank : 659)	θ value	5.27518 (rank : 381)
Query Neighborhood Hits	451	Target Neighborhood Hits	545	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

DYHC_HUMAN
NC score	0.034372 (rank : 660)	θ value	3.0926 (rank : 339)
Query Neighborhood Hits	451	Target Neighborhood Hits	733	Shared Neighborhood Hits	153
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.034246 (rank : 661)	θ value	3.0926 (rank : 340)
Query Neighborhood Hits	451	Target Neighborhood Hits	729	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

ENKUR_MOUSE
NC score	0.032191 (rank : 662)	θ value	0.813845 (rank : 276)
Query Neighborhood Hits	451	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

MRCKB_HUMAN
NC score	0.030784 (rank : 663)	θ value	0.365318 (rank : 242)
Query Neighborhood Hits	451	Target Neighborhood Hits	2239	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
NC score	0.029326 (rank : 664)	θ value	0.21417 (rank : 226)
Query Neighborhood Hits	451	Target Neighborhood Hits	2180	Shared Neighborhood Hits	221
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

GBP1_MOUSE
NC score	0.028752 (rank : 665)	θ value	1.06291 (rank : 291)
Query Neighborhood Hits	451	Target Neighborhood Hits	302	Shared Neighborhood Hits	99
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

ROCK2_HUMAN
NC score	0.028283 (rank : 666)	θ value	1.38821 (rank : 307)
Query Neighborhood Hits	451	Target Neighborhood Hits	2073	Shared Neighborhood Hits	219
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

VIME_MOUSE
NC score	0.027433 (rank : 667)	θ value	4.03905 (rank : 371)
Query Neighborhood Hits	451	Target Neighborhood Hits	716	Shared Neighborhood Hits	161
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

SYCP3_MOUSE
NC score	0.027199 (rank : 668)	θ value	5.27518 (rank : 395)
Query Neighborhood Hits	451	Target Neighborhood Hits	155	Shared Neighborhood Hits	61
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

ROCK2_MOUSE
NC score	0.026904 (rank : 669)	θ value	3.0926 (rank : 354)
Query Neighborhood Hits	451	Target Neighborhood Hits	2072	Shared Neighborhood Hits	218
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CS029_HUMAN
NC score	0.026739 (rank : 670)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

BSN_MOUSE
NC score	0.026671 (rank : 671)	θ value	0.813845 (rank : 274)
Query Neighborhood Hits	451	Target Neighborhood Hits	2057	Shared Neighborhood Hits	133
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

VIME_HUMAN
NC score	0.026103 (rank : 672)	θ value	4.03905 (rank : 370)
Query Neighborhood Hits	451	Target Neighborhood Hits	706	Shared Neighborhood Hits	161
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

STK10_MOUSE
NC score	0.025246 (rank : 673)	θ value	0.0563607 (rank : 193)
Query Neighborhood Hits	451	Target Neighborhood Hits	2132	Shared Neighborhood Hits	207
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

LAMA2_MOUSE
NC score	0.025240 (rank : 674)	θ value	1.06291 (rank : 294)
Query Neighborhood Hits	451	Target Neighborhood Hits	1198	Shared Neighborhood Hits	141
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KI20A_HUMAN
NC score	0.025204 (rank : 675)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	91
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

NOE1_MOUSE
NC score	0.023781 (rank : 676)	θ value	3.0926 (rank : 350)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	93
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NOE1_HUMAN
NC score	0.023336 (rank : 677)	θ value	2.36792 (rank : 332)
Query Neighborhood Hits	451	Target Neighborhood Hits	266	Shared Neighborhood Hits	90
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

ZN318_HUMAN
NC score	0.022790 (rank : 678)	θ value	5.27518 (rank : 397)
Query Neighborhood Hits	451	Target Neighborhood Hits	497	Shared Neighborhood Hits	92
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

EXOC3_MOUSE
NC score	0.021875 (rank : 679)	θ value	1.81305 (rank : 316)
Query Neighborhood Hits	451	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

LAMA2_HUMAN
NC score	0.020688 (rank : 680)	θ value	0.125558 (rank : 211)
Query Neighborhood Hits	451	Target Neighborhood Hits	1092	Shared Neighborhood Hits	127
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

STK10_HUMAN
NC score	0.020479 (rank : 681)	θ value	0.125558 (rank : 212)
Query Neighborhood Hits	451	Target Neighborhood Hits	1921	Shared Neighborhood Hits	192
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SEPT7_HUMAN
NC score	0.020300 (rank : 682)	θ value	3.0926 (rank : 355)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	109
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

GIMA4_HUMAN
NC score	0.019575 (rank : 683)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

KIF6_HUMAN
NC score	0.019518 (rank : 684)	θ value	0.47712 (rank : 250)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	81
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

EXOC3_HUMAN
NC score	0.019504 (rank : 685)	θ value	3.0926 (rank : 341)
Query Neighborhood Hits	451	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

CLC4M_HUMAN
NC score	0.018847 (rank : 686)	θ value	0.0330416 (rank : 171)
Query Neighborhood Hits	451	Target Neighborhood Hits	291	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

SLK_MOUSE
NC score	0.018623 (rank : 687)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	451	Target Neighborhood Hits	1798	Shared Neighborhood Hits	194
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SEPT7_MOUSE
NC score	0.018429 (rank : 688)	θ value	3.0926 (rank : 356)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	95
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

IF2M_MOUSE
NC score	0.018266 (rank : 689)	θ value	0.279714 (rank : 233)
Query Neighborhood Hits	451	Target Neighborhood Hits	183	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

K1C12_HUMAN
NC score	0.017922 (rank : 690)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	451	Target Neighborhood Hits	372	Shared Neighborhood Hits	107
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

RNH2B_MOUSE
NC score	0.016325 (rank : 691)	θ value	0.62314 (rank : 267)
Query Neighborhood Hits	451	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZV0, Q9D014	Gene names	Dleu8, Rnaseh2b
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) (Deleted in lymphocytic leukemia 8 homolog).

M4K4_HUMAN
NC score	0.016248 (rank : 692)	θ value	0.0431538 (rank : 180)
Query Neighborhood Hits	451	Target Neighborhood Hits	1589	Shared Neighborhood Hits	171
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
NC score	0.015695 (rank : 693)	θ value	0.0431538 (rank : 181)
Query Neighborhood Hits	451	Target Neighborhood Hits	1560	Shared Neighborhood Hits	157
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

IF4G3_HUMAN
NC score	0.013387 (rank : 694)	θ value	3.0926 (rank : 343)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MX1_MOUSE
NC score	0.012764 (rank : 695)	θ value	0.0563607 (rank : 190)
Query Neighborhood Hits	451	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

ERCC5_HUMAN
NC score	0.012336 (rank : 696)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	451	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

NPHP3_HUMAN
NC score	0.012105 (rank : 697)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	451	Target Neighborhood Hits	304	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

ACTN3_MOUSE
NC score	0.011979 (rank : 698)	θ value	0.813845 (rank : 272)
Query Neighborhood Hits	451	Target Neighborhood Hits	265	Shared Neighborhood Hits	64
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

TAOK3_HUMAN
NC score	0.011639 (rank : 699)	θ value	6.88961 (rank : 419)
Query Neighborhood Hits	451	Target Neighborhood Hits	1494	Shared Neighborhood Hits	162
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

ACTN3_HUMAN
NC score	0.011507 (rank : 700)	θ value	0.62314 (rank : 258)
Query Neighborhood Hits	451	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

FA76A_MOUSE
NC score	0.011418 (rank : 701)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	451	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

ARHGC_HUMAN
NC score	0.010360 (rank : 702)	θ value	4.03905 (rank : 360)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

IF4G3_MOUSE
NC score	0.010224 (rank : 703)	θ value	3.0926 (rank : 344)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	36
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MTSS1_HUMAN
NC score	0.009819 (rank : 704)	θ value	6.88961 (rank : 410)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	51
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

ARHGC_MOUSE
NC score	0.009192 (rank : 705)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SC15B_HUMAN
NC score	0.008017 (rank : 706)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	451	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2D4	Gene names	SEC15L2, KIAA0919, SEC15B
Domain Architecture
Description	Exocyst complex component Sec15B.

MKL1_HUMAN
NC score	0.005803 (rank : 707)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	28
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MLL4_HUMAN
NC score	0.004966 (rank : 708)	θ value	5.27518 (rank : 386)
Query Neighborhood Hits	451	Target Neighborhood Hits	722	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SRBP1_MOUSE
NC score	0.004004 (rank : 709)	θ value	3.0926 (rank : 357)
Query Neighborhood Hits	451	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

CD2L1_MOUSE
NC score	0.003341 (rank : 710)	θ value	3.0926 (rank : 338)
Query Neighborhood Hits	451	Target Neighborhood Hits	1463	Shared Neighborhood Hits	124
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CD2L1_HUMAN
NC score	0.003323 (rank : 711)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	451	Target Neighborhood Hits	1467	Shared Neighborhood Hits	128
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

UBP8_MOUSE
NC score	0.002217 (rank : 712)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	451	Target Neighborhood Hits	362	Shared Neighborhood Hits	48
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

CD2L2_HUMAN
NC score	0.002214 (rank : 713)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	451	Target Neighborhood Hits	1439	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

SH21B_HUMAN
NC score	-0.000007 (rank : 714)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

FES_MOUSE
NC score	-0.001560 (rank : 715)	θ value	0.0330416 (rank : 173)
Query Neighborhood Hits	451	Target Neighborhood Hits	980	Shared Neighborhood Hits	61
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

M4K1_HUMAN
NC score	-0.002205 (rank : 716)	θ value	1.06291 (rank : 295)
Query Neighborhood Hits	451	Target Neighborhood Hits	884	Shared Neighborhood Hits	21
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

M4K1_MOUSE
NC score	-0.003629 (rank : 717)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	451	Target Neighborhood Hits	858	Shared Neighborhood Hits	19
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

NEK11_HUMAN
NC score	-0.003916 (rank : 718)	θ value	4.03905 (rank : 368)
Query Neighborhood Hits	451	Target Neighborhood Hits	1043	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

FES_HUMAN
NC score	-0.004922 (rank : 719)	θ value	4.03905 (rank : 365)
Query Neighborhood Hits	451	Target Neighborhood Hits	978	Shared Neighborhood Hits	50
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).