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Network neighborhood for query Sequence : UHRF2_HUMAN

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UHRF2_HUMAN
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UHRF1_HUMAN
θ value	0 (rank : 1)	NC score	0.965771 (rank : 3)
Query Neighborhood Hits	269	Target Neighborhood Hits	272	Shared Neighborhood Hits	226
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	0 (rank : 2)	NC score	0.965244 (rank : 4)
Query Neighborhood Hits	269	Target Neighborhood Hits	278	Shared Neighborhood Hits	224
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	269	Target Neighborhood Hits	269	Shared Neighborhood Hits	269
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	0 (rank : 4)	NC score	0.994662 (rank : 2)
Query Neighborhood Hits	269	Target Neighborhood Hits	275	Shared Neighborhood Hits	253
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BAZ1B_HUMAN
θ value	2.79066e-09 (rank : 5)	NC score	0.386661 (rank : 17)
Query Neighborhood Hits	269	Target Neighborhood Hits	701	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	2.79066e-09 (rank : 6)	NC score	0.409908 (rank : 6)
Query Neighborhood Hits	269	Target Neighborhood Hits	394	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CHD4_MOUSE
θ value	1.06045e-08 (rank : 7)	NC score	0.258441 (rank : 154)
Query Neighborhood Hits	269	Target Neighborhood Hits	408	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

PHF14_HUMAN
θ value	1.06045e-08 (rank : 8)	NC score	0.332375 (rank : 67)
Query Neighborhood Hits	269	Target Neighborhood Hits	447	Shared Neighborhood Hits	81
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

MLL3_HUMAN
θ value	1.38499e-08 (rank : 9)	NC score	0.305230 (rank : 103)
Query Neighborhood Hits	269	Target Neighborhood Hits	1644	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	1.38499e-08 (rank : 10)	NC score	0.322410 (rank : 79)
Query Neighborhood Hits	269	Target Neighborhood Hits	1399	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF14_MOUSE
θ value	1.38499e-08 (rank : 11)	NC score	0.338851 (rank : 57)
Query Neighborhood Hits	269	Target Neighborhood Hits	342	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

MLL2_HUMAN
θ value	1.80886e-08 (rank : 12)	NC score	0.321643 (rank : 82)
Query Neighborhood Hits	269	Target Neighborhood Hits	1788	Shared Neighborhood Hits	110
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RSF1_HUMAN
θ value	5.26297e-08 (rank : 13)	NC score	0.401849 (rank : 8)
Query Neighborhood Hits	269	Target Neighborhood Hits	539	Shared Neighborhood Hits	77
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CHD5_HUMAN
θ value	1.17247e-07 (rank : 14)	NC score	0.263803 (rank : 151)
Query Neighborhood Hits	269	Target Neighborhood Hits	349	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_HUMAN
θ value	1.53129e-07 (rank : 15)	NC score	0.256104 (rank : 155)
Query Neighborhood Hits	269	Target Neighborhood Hits	365	Shared Neighborhood Hits	86
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

JAD1D_MOUSE
θ value	2.61198e-07 (rank : 16)	NC score	0.335904 (rank : 62)
Query Neighborhood Hits	269	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

DPF1_MOUSE
θ value	4.45536e-07 (rank : 17)	NC score	0.388359 (rank : 15)
Query Neighborhood Hits	269	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

CHD3_HUMAN
θ value	5.81887e-07 (rank : 18)	NC score	0.253544 (rank : 158)
Query Neighborhood Hits	269	Target Neighborhood Hits	397	Shared Neighborhood Hits	86
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

JAD1C_HUMAN
θ value	5.81887e-07 (rank : 19)	NC score	0.339389 (rank : 54)
Query Neighborhood Hits	269	Target Neighborhood Hits	187	Shared Neighborhood Hits	70
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	5.81887e-07 (rank : 20)	NC score	0.339949 (rank : 52)
Query Neighborhood Hits	269	Target Neighborhood Hits	164	Shared Neighborhood Hits	70
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

BAZ1A_HUMAN
θ value	7.59969e-07 (rank : 21)	NC score	0.367767 (rank : 25)
Query Neighborhood Hits	269	Target Neighborhood Hits	693	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

JAD1A_HUMAN
θ value	2.21117e-06 (rank : 22)	NC score	0.343419 (rank : 43)
Query Neighborhood Hits	269	Target Neighborhood Hits	328	Shared Neighborhood Hits	75
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1D_HUMAN
θ value	2.88788e-06 (rank : 23)	NC score	0.338982 (rank : 56)
Query Neighborhood Hits	269	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

BPTF_HUMAN
θ value	4.92598e-06 (rank : 24)	NC score	0.291253 (rank : 130)
Query Neighborhood Hits	269	Target Neighborhood Hits	786	Shared Neighborhood Hits	84
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

REQU_HUMAN
θ value	4.92598e-06 (rank : 25)	NC score	0.380613 (rank : 18)
Query Neighborhood Hits	269	Target Neighborhood Hits	523	Shared Neighborhood Hits	73
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BAZ2A_MOUSE
θ value	6.43352e-06 (rank : 26)	NC score	0.315706 (rank : 94)
Query Neighborhood Hits	269	Target Neighborhood Hits	744	Shared Neighborhood Hits	77
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

TRI31_HUMAN
θ value	6.43352e-06 (rank : 27)	NC score	0.391173 (rank : 14)
Query Neighborhood Hits	269	Target Neighborhood Hits	299	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

REQU_MOUSE
θ value	8.40245e-06 (rank : 28)	NC score	0.379446 (rank : 19)
Query Neighborhood Hits	269	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RNF8_HUMAN
θ value	8.40245e-06 (rank : 29)	NC score	0.329134 (rank : 69)
Query Neighborhood Hits	269	Target Neighborhood Hits	622	Shared Neighborhood Hits	157
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RN125_HUMAN
θ value	1.09739e-05 (rank : 30)	NC score	0.412523 (rank : 5)
Query Neighborhood Hits	269	Target Neighborhood Hits	230	Shared Neighborhood Hits	152
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RNF8_MOUSE
θ value	1.09739e-05 (rank : 31)	NC score	0.339086 (rank : 55)
Query Neighborhood Hits	269	Target Neighborhood Hits	618	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

UBIQ_HUMAN
θ value	1.43324e-05 (rank : 32)	NC score	0.292065 (rank : 128)
Query Neighborhood Hits	269	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	P62988, P02248, P02249, P02250, Q29120, Q6LBL4, Q6LDU5, Q91887, Q91888, Q9BWD6, Q9BX98, Q9UEF2, Q9UEG1, Q9UEK8, Q9UPK7	Gene names	RPS27A, UBA80, UBCEP1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

UBIQ_MOUSE
θ value	1.43324e-05 (rank : 33)	NC score	0.292065 (rank : 129)
Query Neighborhood Hits	269	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	P62991, P02248, P02249, P02250, Q29120, Q62317, Q64223, Q8VCH1, Q91887, Q91888, Q9CXY4, Q9CZM0, Q9D1R5, Q9D8D9, Q9ET23, Q9ET24, Q9Z0H9	Gene names	Rps27a, Uba80, Ubcep1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

BAZ2A_HUMAN
θ value	1.87187e-05 (rank : 34)	NC score	0.316394 (rank : 93)
Query Neighborhood Hits	269	Target Neighborhood Hits	780	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2B_HUMAN
θ value	3.19293e-05 (rank : 35)	NC score	0.304041 (rank : 107)
Query Neighborhood Hits	269	Target Neighborhood Hits	803	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MYST4_HUMAN
θ value	3.19293e-05 (rank : 36)	NC score	0.313318 (rank : 95)
Query Neighborhood Hits	269	Target Neighborhood Hits	671	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

DPF1_HUMAN
θ value	4.1701e-05 (rank : 37)	NC score	0.405824 (rank : 7)
Query Neighborhood Hits	269	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MYST4_MOUSE
θ value	4.1701e-05 (rank : 38)	NC score	0.319859 (rank : 86)
Query Neighborhood Hits	269	Target Neighborhood Hits	416	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PF21A_HUMAN
θ value	5.44631e-05 (rank : 39)	NC score	0.393215 (rank : 13)
Query Neighborhood Hits	269	Target Neighborhood Hits	303	Shared Neighborhood Hits	79
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	7.1131e-05 (rank : 40)	NC score	0.395471 (rank : 11)
Query Neighborhood Hits	269	Target Neighborhood Hits	285	Shared Neighborhood Hits	77
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

TRI12_MOUSE
θ value	7.1131e-05 (rank : 41)	NC score	0.373437 (rank : 23)
Query Neighborhood Hits	269	Target Neighborhood Hits	387	Shared Neighborhood Hits	159
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI17_HUMAN
θ value	7.1131e-05 (rank : 42)	NC score	0.326876 (rank : 71)
Query Neighborhood Hits	269	Target Neighborhood Hits	318	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI25_MOUSE
θ value	7.1131e-05 (rank : 43)	NC score	0.360090 (rank : 31)
Query Neighborhood Hits	269	Target Neighborhood Hits	446	Shared Neighborhood Hits	160
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

HRX_HUMAN
θ value	9.29e-05 (rank : 44)	NC score	0.237697 (rank : 165)
Query Neighborhood Hits	269	Target Neighborhood Hits	825	Shared Neighborhood Hits	75
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TRI60_HUMAN
θ value	9.29e-05 (rank : 45)	NC score	0.332553 (rank : 66)
Query Neighborhood Hits	269	Target Neighborhood Hits	357	Shared Neighborhood Hits	163
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

MYST3_HUMAN
θ value	0.000121331 (rank : 46)	NC score	0.292067 (rank : 127)
Query Neighborhood Hits	269	Target Neighborhood Hits	772	Shared Neighborhood Hits	79
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.000121331 (rank : 47)	NC score	0.294977 (rank : 122)
Query Neighborhood Hits	269	Target Neighborhood Hits	688	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PHF10_HUMAN
θ value	0.000121331 (rank : 48)	NC score	0.397676 (rank : 10)
Query Neighborhood Hits	269	Target Neighborhood Hits	151	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	0.000121331 (rank : 49)	NC score	0.399266 (rank : 9)
Query Neighborhood Hits	269	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

RING1_HUMAN
θ value	0.000121331 (rank : 50)	NC score	0.377969 (rank : 20)
Query Neighborhood Hits	269	Target Neighborhood Hits	219	Shared Neighborhood Hits	132
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.000121331 (rank : 51)	NC score	0.373493 (rank : 22)
Query Neighborhood Hits	269	Target Neighborhood Hits	220	Shared Neighborhood Hits	132
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI11_HUMAN
θ value	0.000121331 (rank : 52)	NC score	0.324765 (rank : 76)
Query Neighborhood Hits	269	Target Neighborhood Hits	316	Shared Neighborhood Hits	162
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	0.000121331 (rank : 53)	NC score	0.326334 (rank : 73)
Query Neighborhood Hits	269	Target Neighborhood Hits	329	Shared Neighborhood Hits	166
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI63_HUMAN
θ value	0.000158464 (rank : 54)	NC score	0.347369 (rank : 39)
Query Neighborhood Hits	269	Target Neighborhood Hits	298	Shared Neighborhood Hits	131
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM4_HUMAN
θ value	0.000158464 (rank : 55)	NC score	0.340013 (rank : 51)
Query Neighborhood Hits	269	Target Neighborhood Hits	321	Shared Neighborhood Hits	159
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

RING2_HUMAN
θ value	0.00020696 (rank : 56)	NC score	0.362846 (rank : 30)
Query Neighborhood Hits	269	Target Neighborhood Hits	201	Shared Neighborhood Hits	132
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.00020696 (rank : 57)	NC score	0.362898 (rank : 29)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	132
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRI63_MOUSE
θ value	0.00020696 (rank : 58)	NC score	0.350559 (rank : 34)
Query Neighborhood Hits	269	Target Neighborhood Hits	240	Shared Neighborhood Hits	131
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI17_MOUSE
θ value	0.000270298 (rank : 59)	NC score	0.317764 (rank : 91)
Query Neighborhood Hits	269	Target Neighborhood Hits	620	Shared Neighborhood Hits	167
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI27_MOUSE
θ value	0.00035302 (rank : 60)	NC score	0.295440 (rank : 121)
Query Neighborhood Hits	269	Target Neighborhood Hits	261	Shared Neighborhood Hits	145
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

BRCA1_HUMAN
θ value	0.000461057 (rank : 61)	NC score	0.341420 (rank : 47)
Query Neighborhood Hits	269	Target Neighborhood Hits	381	Shared Neighborhood Hits	154
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RN125_MOUSE
θ value	0.000461057 (rank : 62)	NC score	0.386932 (rank : 16)
Query Neighborhood Hits	269	Target Neighborhood Hits	220	Shared Neighborhood Hits	143
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN168_HUMAN
θ value	0.000461057 (rank : 63)	NC score	0.374891 (rank : 21)
Query Neighborhood Hits	269	Target Neighborhood Hits	370	Shared Neighborhood Hits	144
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI39_HUMAN
θ value	0.000461057 (rank : 64)	NC score	0.313257 (rank : 96)
Query Neighborhood Hits	269	Target Neighborhood Hits	693	Shared Neighborhood Hits	165
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.000461057 (rank : 65)	NC score	0.312324 (rank : 98)
Query Neighborhood Hits	269	Target Neighborhood Hits	691	Shared Neighborhood Hits	168
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RAG1_HUMAN
θ value	0.000602161 (rank : 66)	NC score	0.330903 (rank : 68)
Query Neighborhood Hits	269	Target Neighborhood Hits	203	Shared Neighborhood Hits	129
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI46_HUMAN
θ value	0.000602161 (rank : 67)	NC score	0.298712 (rank : 113)
Query Neighborhood Hits	269	Target Neighborhood Hits	291	Shared Neighborhood Hits	142
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	0.000602161 (rank : 68)	NC score	0.299363 (rank : 112)
Query Neighborhood Hits	269	Target Neighborhood Hits	287	Shared Neighborhood Hits	141
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI56_MOUSE
θ value	0.000602161 (rank : 69)	NC score	0.317198 (rank : 92)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	150
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

BRE1B_HUMAN
θ value	0.000786445 (rank : 70)	NC score	0.125755 (rank : 278)
Query Neighborhood Hits	269	Target Neighborhood Hits	1040	Shared Neighborhood Hits	131
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	0.000786445 (rank : 71)	NC score	0.128294 (rank : 275)
Query Neighborhood Hits	269	Target Neighborhood Hits	970	Shared Neighborhood Hits	123
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

PF21B_MOUSE
θ value	0.000786445 (rank : 72)	NC score	0.351195 (rank : 33)
Query Neighborhood Hits	269	Target Neighborhood Hits	278	Shared Neighborhood Hits	71
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RAG1_MOUSE
θ value	0.00102713 (rank : 73)	NC score	0.326045 (rank : 74)
Query Neighborhood Hits	269	Target Neighborhood Hits	189	Shared Neighborhood Hits	131
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI35_HUMAN
θ value	0.00102713 (rank : 74)	NC score	0.342341 (rank : 45)
Query Neighborhood Hits	269	Target Neighborhood Hits	382	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

BRCA1_MOUSE
θ value	0.00134147 (rank : 75)	NC score	0.334579 (rank : 64)
Query Neighborhood Hits	269	Target Neighborhood Hits	436	Shared Neighborhood Hits	161
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

MLL4_HUMAN
θ value	0.00134147 (rank : 76)	NC score	0.227225 (rank : 172)
Query Neighborhood Hits	269	Target Neighborhood Hits	722	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TRI25_HUMAN
θ value	0.00134147 (rank : 77)	NC score	0.339469 (rank : 53)
Query Neighborhood Hits	269	Target Neighborhood Hits	472	Shared Neighborhood Hits	162
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI27_HUMAN
θ value	0.00134147 (rank : 78)	NC score	0.294185 (rank : 123)
Query Neighborhood Hits	269	Target Neighborhood Hits	273	Shared Neighborhood Hits	152
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI65_MOUSE
θ value	0.00134147 (rank : 79)	NC score	0.360008 (rank : 32)
Query Neighborhood Hits	269	Target Neighborhood Hits	340	Shared Neighborhood Hits	167
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

AIRE_MOUSE
θ value	0.00175202 (rank : 80)	NC score	0.373163 (rank : 24)
Query Neighborhood Hits	269	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PHF12_MOUSE
θ value	0.00175202 (rank : 81)	NC score	0.336699 (rank : 60)
Query Neighborhood Hits	269	Target Neighborhood Hits	172	Shared Neighborhood Hits	73
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

AIRE_HUMAN
θ value	0.00228821 (rank : 82)	NC score	0.394914 (rank : 12)
Query Neighborhood Hits	269	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

RN168_MOUSE
θ value	0.00228821 (rank : 83)	NC score	0.345098 (rank : 41)
Query Neighborhood Hits	269	Target Neighborhood Hits	440	Shared Neighborhood Hits	141
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRAF3_MOUSE
θ value	0.00228821 (rank : 84)	NC score	0.212394 (rank : 183)
Query Neighborhood Hits	269	Target Neighborhood Hits	476	Shared Neighborhood Hits	116
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRI54_HUMAN
θ value	0.00228821 (rank : 85)	NC score	0.349357 (rank : 36)
Query Neighborhood Hits	269	Target Neighborhood Hits	209	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	0.00228821 (rank : 86)	NC score	0.347577 (rank : 38)
Query Neighborhood Hits	269	Target Neighborhood Hits	197	Shared Neighborhood Hits	129
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI56_HUMAN
θ value	0.00228821 (rank : 87)	NC score	0.318684 (rank : 89)
Query Neighborhood Hits	269	Target Neighborhood Hits	339	Shared Neighborhood Hits	158
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM5_HUMAN
θ value	0.00228821 (rank : 88)	NC score	0.326845 (rank : 72)
Query Neighborhood Hits	269	Target Neighborhood Hits	424	Shared Neighborhood Hits	162
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

UBL4A_HUMAN
θ value	0.00228821 (rank : 89)	NC score	0.229625 (rank : 169)
Query Neighborhood Hits	269	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	P11441	Gene names	UBL4A, DXS254E, GDX, UBL4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

TRAF3_HUMAN
θ value	0.00298849 (rank : 90)	NC score	0.205347 (rank : 192)
Query Neighborhood Hits	269	Target Neighborhood Hits	463	Shared Neighborhood Hits	112
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRI38_HUMAN
θ value	0.00298849 (rank : 91)	NC score	0.303770 (rank : 108)
Query Neighborhood Hits	269	Target Neighborhood Hits	373	Shared Neighborhood Hits	151
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

BAT3_HUMAN
θ value	0.00390308 (rank : 92)	NC score	0.131524 (rank : 271)
Query Neighborhood Hits	269	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MTF2_HUMAN
θ value	0.00390308 (rank : 93)	NC score	0.227353 (rank : 171)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	0.00390308 (rank : 94)	NC score	0.225767 (rank : 174)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PF21B_HUMAN
θ value	0.00390308 (rank : 95)	NC score	0.347687 (rank : 37)
Query Neighborhood Hits	269	Target Neighborhood Hits	197	Shared Neighborhood Hits	67
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	0.00390308 (rank : 96)	NC score	0.333704 (rank : 65)
Query Neighborhood Hits	269	Target Neighborhood Hits	174	Shared Neighborhood Hits	73
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

RO52_MOUSE
θ value	0.00390308 (rank : 97)	NC score	0.311161 (rank : 100)
Query Neighborhood Hits	269	Target Neighborhood Hits	360	Shared Neighborhood Hits	162
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TIF1B_HUMAN
θ value	0.00390308 (rank : 98)	NC score	0.322479 (rank : 78)
Query Neighborhood Hits	269	Target Neighborhood Hits	312	Shared Neighborhood Hits	134
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRAF2_HUMAN
θ value	0.00390308 (rank : 99)	NC score	0.211030 (rank : 187)
Query Neighborhood Hits	269	Target Neighborhood Hits	402	Shared Neighborhood Hits	115
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRI18_HUMAN
θ value	0.00390308 (rank : 100)	NC score	0.295455 (rank : 120)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	152
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	0.00390308 (rank : 101)	NC score	0.297247 (rank : 116)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	152
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI55_HUMAN
θ value	0.00390308 (rank : 102)	NC score	0.341364 (rank : 48)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM1_HUMAN
θ value	0.00390308 (rank : 103)	NC score	0.298045 (rank : 114)
Query Neighborhood Hits	269	Target Neighborhood Hits	345	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.00390308 (rank : 104)	NC score	0.296325 (rank : 117)
Query Neighborhood Hits	269	Target Neighborhood Hits	361	Shared Neighborhood Hits	154
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

BRE1A_HUMAN
θ value	0.00509761 (rank : 105)	NC score	0.105402 (rank : 294)
Query Neighborhood Hits	269	Target Neighborhood Hits	1071	Shared Neighborhood Hits	117
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	0.00509761 (rank : 106)	NC score	0.103445 (rank : 296)
Query Neighborhood Hits	269	Target Neighborhood Hits	1025	Shared Neighborhood Hits	111
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

TRI35_MOUSE
θ value	0.00509761 (rank : 107)	NC score	0.336665 (rank : 61)
Query Neighborhood Hits	269	Target Neighborhood Hits	465	Shared Neighborhood Hits	170
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI65_HUMAN
θ value	0.00509761 (rank : 108)	NC score	0.363147 (rank : 27)
Query Neighborhood Hits	269	Target Neighborhood Hits	330	Shared Neighborhood Hits	166
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TIF1B_MOUSE
θ value	0.00665767 (rank : 109)	NC score	0.325259 (rank : 75)
Query Neighborhood Hits	269	Target Neighborhood Hits	276	Shared Neighborhood Hits	131
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

NEDD8_HUMAN
θ value	0.00869519 (rank : 110)	NC score	0.289050 (rank : 133)
Query Neighborhood Hits	269	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q15843, Q6LES6	Gene names	NEDD8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin).

NEDD8_MOUSE
θ value	0.00869519 (rank : 111)	NC score	0.288750 (rank : 134)
Query Neighborhood Hits	269	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	P29595	Gene names	Nedd8, Nedd-8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8).

TRI13_HUMAN
θ value	0.00869519 (rank : 112)	NC score	0.363159 (rank : 26)
Query Neighborhood Hits	269	Target Neighborhood Hits	274	Shared Neighborhood Hits	158
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	0.00869519 (rank : 113)	NC score	0.363097 (rank : 28)
Query Neighborhood Hits	269	Target Neighborhood Hits	282	Shared Neighborhood Hits	159
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI22_HUMAN
θ value	0.00869519 (rank : 114)	NC score	0.321731 (rank : 81)
Query Neighborhood Hits	269	Target Neighborhood Hits	396	Shared Neighborhood Hits	163
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI30_MOUSE
θ value	0.00869519 (rank : 115)	NC score	0.334922 (rank : 63)
Query Neighborhood Hits	269	Target Neighborhood Hits	434	Shared Neighborhood Hits	161
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI50_MOUSE
θ value	0.00869519 (rank : 116)	NC score	0.321104 (rank : 83)
Query Neighborhood Hits	269	Target Neighborhood Hits	326	Shared Neighborhood Hits	166
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM3_HUMAN
θ value	0.00869519 (rank : 117)	NC score	0.292985 (rank : 126)
Query Neighborhood Hits	269	Target Neighborhood Hits	357	Shared Neighborhood Hits	155
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

ZMY11_MOUSE
θ value	0.00869519 (rank : 118)	NC score	0.226214 (rank : 173)
Query Neighborhood Hits	269	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BFAR_HUMAN
θ value	0.0113563 (rank : 119)	NC score	0.343205 (rank : 44)
Query Neighborhood Hits	269	Target Neighborhood Hits	222	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN166_MOUSE
θ value	0.0113563 (rank : 120)	NC score	0.349842 (rank : 35)
Query Neighborhood Hits	269	Target Neighborhood Hits	248	Shared Neighborhood Hits	146
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF39_HUMAN
θ value	0.0113563 (rank : 121)	NC score	0.277408 (rank : 144)
Query Neighborhood Hits	269	Target Neighborhood Hits	200	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI10_MOUSE
θ value	0.0113563 (rank : 122)	NC score	0.309601 (rank : 101)
Query Neighborhood Hits	269	Target Neighborhood Hits	285	Shared Neighborhood Hits	157
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI60_MOUSE
θ value	0.0113563 (rank : 123)	NC score	0.299455 (rank : 111)
Query Neighborhood Hits	269	Target Neighborhood Hits	240	Shared Neighborhood Hits	143
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRAF6_MOUSE
θ value	0.0148317 (rank : 124)	NC score	0.283372 (rank : 139)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	144
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI43_HUMAN
θ value	0.0148317 (rank : 125)	NC score	0.322176 (rank : 80)
Query Neighborhood Hits	269	Target Neighborhood Hits	341	Shared Neighborhood Hits	158
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

BFAR_MOUSE
θ value	0.0193708 (rank : 126)	NC score	0.337211 (rank : 59)
Query Neighborhood Hits	269	Target Neighborhood Hits	232	Shared Neighborhood Hits	137
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RO52_HUMAN
θ value	0.0193708 (rank : 127)	NC score	0.305690 (rank : 102)
Query Neighborhood Hits	269	Target Neighborhood Hits	419	Shared Neighborhood Hits	165
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SMRA3_MOUSE
θ value	0.0193708 (rank : 128)	NC score	0.224778 (rank : 177)
Query Neighborhood Hits	269	Target Neighborhood Hits	267	Shared Neighborhood Hits	149
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRAF5_MOUSE
θ value	0.0193708 (rank : 129)	NC score	0.230919 (rank : 168)
Query Neighborhood Hits	269	Target Neighborhood Hits	355	Shared Neighborhood Hits	114
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI34_HUMAN
θ value	0.0193708 (rank : 130)	NC score	0.312366 (rank : 97)
Query Neighborhood Hits	269	Target Neighborhood Hits	416	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI36_MOUSE
θ value	0.0193708 (rank : 131)	NC score	0.262693 (rank : 152)
Query Neighborhood Hits	269	Target Neighborhood Hits	266	Shared Neighborhood Hits	123
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

BAT3_MOUSE
θ value	0.0252991 (rank : 132)	NC score	0.129788 (rank : 272)
Query Neighborhood Hits	269	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

RN166_HUMAN
θ value	0.0252991 (rank : 133)	NC score	0.345943 (rank : 40)
Query Neighborhood Hits	269	Target Neighborhood Hits	240	Shared Neighborhood Hits	147
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRAF6_HUMAN
θ value	0.0252991 (rank : 134)	NC score	0.274109 (rank : 145)
Query Neighborhood Hits	269	Target Neighborhood Hits	267	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

MYLIP_MOUSE
θ value	0.0330416 (rank : 135)	NC score	0.081299 (rank : 324)
Query Neighborhood Hits	269	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

TRAF2_MOUSE
θ value	0.0330416 (rank : 136)	NC score	0.204530 (rank : 193)
Query Neighborhood Hits	269	Target Neighborhood Hits	394	Shared Neighborhood Hits	112
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF4_HUMAN
θ value	0.0330416 (rank : 137)	NC score	0.216238 (rank : 179)
Query Neighborhood Hits	269	Target Neighborhood Hits	373	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRIM2_HUMAN
θ value	0.0330416 (rank : 138)	NC score	0.287459 (rank : 135)
Query Neighborhood Hits	269	Target Neighborhood Hits	330	Shared Neighborhood Hits	162
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

CHFR_HUMAN
θ value	0.0431538 (rank : 139)	NC score	0.266080 (rank : 148)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	139
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.0431538 (rank : 140)	NC score	0.263933 (rank : 150)
Query Neighborhood Hits	269	Target Neighborhood Hits	264	Shared Neighborhood Hits	139
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI36_HUMAN
θ value	0.0431538 (rank : 141)	NC score	0.261169 (rank : 153)
Query Neighborhood Hits	269	Target Neighborhood Hits	282	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM2_MOUSE
θ value	0.0431538 (rank : 142)	NC score	0.286006 (rank : 136)
Query Neighborhood Hits	269	Target Neighborhood Hits	331	Shared Neighborhood Hits	161
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_MOUSE
θ value	0.0431538 (rank : 143)	NC score	0.285606 (rank : 137)
Query Neighborhood Hits	269	Target Neighborhood Hits	351	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM6_MOUSE
θ value	0.0431538 (rank : 144)	NC score	0.304430 (rank : 106)
Query Neighborhood Hits	269	Target Neighborhood Hits	451	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM8_HUMAN
θ value	0.0431538 (rank : 145)	NC score	0.342295 (rank : 46)
Query Neighborhood Hits	269	Target Neighborhood Hits	650	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	0.0431538 (rank : 146)	NC score	0.340207 (rank : 50)
Query Neighborhood Hits	269	Target Neighborhood Hits	674	Shared Neighborhood Hits	159
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UBL4A_MOUSE
θ value	0.0431538 (rank : 147)	NC score	0.191608 (rank : 208)
Query Neighborhood Hits	269	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	P21126	Gene names	Ubl4a, Gdx, Ubl4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

ZMY11_HUMAN
θ value	0.0563607 (rank : 148)	NC score	0.210928 (rank : 188)
Query Neighborhood Hits	269	Target Neighborhood Hits	201	Shared Neighborhood Hits	57
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZN313_HUMAN
θ value	0.0563607 (rank : 149)	NC score	0.337695 (rank : 58)
Query Neighborhood Hits	269	Target Neighborhood Hits	264	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	0.0563607 (rank : 150)	NC score	0.343453 (rank : 42)
Query Neighborhood Hits	269	Target Neighborhood Hits	273	Shared Neighborhood Hits	157
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

LNX2_HUMAN
θ value	0.0736092 (rank : 151)	NC score	0.163998 (rank : 238)
Query Neighborhood Hits	269	Target Neighborhood Hits	389	Shared Neighborhood Hits	145
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MYLIP_HUMAN
θ value	0.0736092 (rank : 152)	NC score	0.085838 (rank : 315)
Query Neighborhood Hits	269	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

SMRA3_HUMAN
θ value	0.0736092 (rank : 153)	NC score	0.225242 (rank : 176)
Query Neighborhood Hits	269	Target Neighborhood Hits	265	Shared Neighborhood Hits	150
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI50_HUMAN
θ value	0.0736092 (rank : 154)	NC score	0.312227 (rank : 99)
Query Neighborhood Hits	269	Target Neighborhood Hits	294	Shared Neighborhood Hits	164
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

LNX2_MOUSE
θ value	0.0961366 (rank : 155)	NC score	0.161231 (rank : 239)
Query Neighborhood Hits	269	Target Neighborhood Hits	407	Shared Neighborhood Hits	146
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

NSD1_HUMAN
θ value	0.0961366 (rank : 156)	NC score	0.201014 (rank : 198)
Query Neighborhood Hits	269	Target Neighborhood Hits	427	Shared Neighborhood Hits	75
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0.0961366 (rank : 157)	NC score	0.203290 (rank : 195)
Query Neighborhood Hits	269	Target Neighborhood Hits	472	Shared Neighborhood Hits	75
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RFWD2_HUMAN
θ value	0.0961366 (rank : 158)	NC score	0.192363 (rank : 205)
Query Neighborhood Hits	269	Target Neighborhood Hits	518	Shared Neighborhood Hits	156
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.0961366 (rank : 159)	NC score	0.191707 (rank : 207)
Query Neighborhood Hits	269	Target Neighborhood Hits	535	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RNF34_HUMAN
θ value	0.0961366 (rank : 160)	NC score	0.119519 (rank : 282)
Query Neighborhood Hits	269	Target Neighborhood Hits	153	Shared Neighborhood Hits	66
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

TAF3_HUMAN
θ value	0.0961366 (rank : 161)	NC score	0.192911 (rank : 203)
Query Neighborhood Hits	269	Target Neighborhood Hits	568	Shared Neighborhood Hits	65
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI10_HUMAN
θ value	0.0961366 (rank : 162)	NC score	0.304511 (rank : 105)
Query Neighborhood Hits	269	Target Neighborhood Hits	315	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI26_MOUSE
θ value	0.0961366 (rank : 163)	NC score	0.319499 (rank : 88)
Query Neighborhood Hits	269	Target Neighborhood Hits	339	Shared Neighborhood Hits	163
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI40_HUMAN
θ value	0.0961366 (rank : 164)	NC score	0.341272 (rank : 49)
Query Neighborhood Hits	269	Target Neighborhood Hits	279	Shared Neighborhood Hits	157
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM6_HUMAN
θ value	0.0961366 (rank : 165)	NC score	0.301751 (rank : 109)
Query Neighborhood Hits	269	Target Neighborhood Hits	412	Shared Neighborhood Hits	161
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TAF3_MOUSE
θ value	0.125558 (rank : 166)	NC score	0.183940 (rank : 217)
Query Neighborhood Hits	269	Target Neighborhood Hits	463	Shared Neighborhood Hits	59
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRAF5_HUMAN
θ value	0.125558 (rank : 167)	NC score	0.204393 (rank : 194)
Query Neighborhood Hits	269	Target Neighborhood Hits	396	Shared Neighborhood Hits	113
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRI26_HUMAN
θ value	0.125558 (rank : 168)	NC score	0.320803 (rank : 84)
Query Neighborhood Hits	269	Target Neighborhood Hits	335	Shared Neighborhood Hits	163
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI34_MOUSE
θ value	0.125558 (rank : 169)	NC score	0.293913 (rank : 124)
Query Neighborhood Hits	269	Target Neighborhood Hits	332	Shared Neighborhood Hits	138
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

BRPF1_HUMAN
θ value	0.163984 (rank : 170)	NC score	0.195445 (rank : 201)
Query Neighborhood Hits	269	Target Neighborhood Hits	259	Shared Neighborhood Hits	70
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRPF3_HUMAN
θ value	0.163984 (rank : 171)	NC score	0.180414 (rank : 222)
Query Neighborhood Hits	269	Target Neighborhood Hits	217	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

RNF34_MOUSE
θ value	0.163984 (rank : 172)	NC score	0.118487 (rank : 284)
Query Neighborhood Hits	269	Target Neighborhood Hits	160	Shared Neighborhood Hits	66
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRI47_HUMAN
θ value	0.163984 (rank : 173)	NC score	0.304518 (rank : 104)
Query Neighborhood Hits	269	Target Neighborhood Hits	286	Shared Neighborhood Hits	149
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

JADE3_HUMAN
θ value	0.21417 (rank : 174)	NC score	0.176500 (rank : 226)
Query Neighborhood Hits	269	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

TRIM7_MOUSE
θ value	0.21417 (rank : 175)	NC score	0.293322 (rank : 125)
Query Neighborhood Hits	269	Target Neighborhood Hits	358	Shared Neighborhood Hits	154
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

JADE3_MOUSE
θ value	0.279714 (rank : 176)	NC score	0.171959 (rank : 231)
Query Neighborhood Hits	269	Target Neighborhood Hits	174	Shared Neighborhood Hits	68
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

PKCB1_HUMAN
θ value	0.279714 (rank : 177)	NC score	0.220065 (rank : 178)
Query Neighborhood Hits	269	Target Neighborhood Hits	488	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRI47_MOUSE
θ value	0.279714 (rank : 178)	NC score	0.296002 (rank : 118)
Query Neighborhood Hits	269	Target Neighborhood Hits	295	Shared Neighborhood Hits	149
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM7_HUMAN
θ value	0.279714 (rank : 179)	NC score	0.295557 (rank : 119)
Query Neighborhood Hits	269	Target Neighborhood Hits	336	Shared Neighborhood Hits	155
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

PCGF4_HUMAN
θ value	0.365318 (rank : 180)	NC score	0.188380 (rank : 213)
Query Neighborhood Hits	269	Target Neighborhood Hits	161	Shared Neighborhood Hits	104
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.365318 (rank : 181)	NC score	0.188453 (rank : 212)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

R113B_HUMAN
θ value	0.365318 (rank : 182)	NC score	0.241794 (rank : 163)
Query Neighborhood Hits	269	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RN169_HUMAN
θ value	0.47712 (rank : 183)	NC score	0.225609 (rank : 175)
Query Neighborhood Hits	269	Target Neighborhood Hits	203	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI41_HUMAN
θ value	0.47712 (rank : 184)	NC score	0.278561 (rank : 142)
Query Neighborhood Hits	269	Target Neighborhood Hits	349	Shared Neighborhood Hits	147
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI52_HUMAN
θ value	0.47712 (rank : 185)	NC score	0.324471 (rank : 77)
Query Neighborhood Hits	269	Target Neighborhood Hits	213	Shared Neighborhood Hits	150
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI68_MOUSE
θ value	0.47712 (rank : 186)	NC score	0.289897 (rank : 132)
Query Neighborhood Hits	269	Target Neighborhood Hits	356	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

BRD1_HUMAN
θ value	0.62314 (rank : 187)	NC score	0.191337 (rank : 209)
Query Neighborhood Hits	269	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

PCGF2_HUMAN
θ value	0.62314 (rank : 188)	NC score	0.184663 (rank : 215)
Query Neighborhood Hits	269	Target Neighborhood Hits	222	Shared Neighborhood Hits	102
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.62314 (rank : 189)	NC score	0.184581 (rank : 216)
Query Neighborhood Hits	269	Target Neighborhood Hits	213	Shared Neighborhood Hits	101
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF6_HUMAN
θ value	0.62314 (rank : 190)	NC score	0.209542 (rank : 189)
Query Neighborhood Hits	269	Target Neighborhood Hits	178	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	0.62314 (rank : 191)	NC score	0.211540 (rank : 186)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	108
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RNF37_MOUSE
θ value	0.62314 (rank : 192)	NC score	0.096419 (rank : 299)
Query Neighborhood Hits	269	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

ZN638_MOUSE
θ value	0.62314 (rank : 193)	NC score	0.028853 (rank : 441)
Query Neighborhood Hits	269	Target Neighborhood Hits	318	Shared Neighborhood Hits	13
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

PZRN3_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.155690 (rank : 247)
Query Neighborhood Hits	269	Target Neighborhood Hits	461	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.813845 (rank : 195)	NC score	0.156866 (rank : 245)
Query Neighborhood Hits	269	Target Neighborhood Hits	447	Shared Neighborhood Hits	148
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

R113A_HUMAN
θ value	1.06291 (rank : 196)	NC score	0.212834 (rank : 182)
Query Neighborhood Hits	269	Target Neighborhood Hits	177	Shared Neighborhood Hits	118
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RNF13_HUMAN
θ value	1.06291 (rank : 197)	NC score	0.084536 (rank : 317)
Query Neighborhood Hits	269	Target Neighborhood Hits	147	Shared Neighborhood Hits	60
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

TRI62_HUMAN
θ value	1.06291 (rank : 198)	NC score	0.280187 (rank : 141)
Query Neighborhood Hits	269	Target Neighborhood Hits	584	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	1.06291 (rank : 199)	NC score	0.285331 (rank : 138)
Query Neighborhood Hits	269	Target Neighborhood Hits	478	Shared Neighborhood Hits	153
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI66_MOUSE
θ value	1.06291 (rank : 200)	NC score	0.255843 (rank : 156)
Query Neighborhood Hits	269	Target Neighborhood Hits	491	Shared Neighborhood Hits	110
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BIRC3_MOUSE
θ value	1.38821 (rank : 201)	NC score	0.055132 (rank : 396)
Query Neighborhood Hits	269	Target Neighborhood Hits	113	Shared Neighborhood Hits	56
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

DCTN4_MOUSE
θ value	1.38821 (rank : 202)	NC score	0.039219 (rank : 436)
Query Neighborhood Hits	269	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

JADE1_HUMAN
θ value	1.38821 (rank : 203)	NC score	0.166006 (rank : 235)
Query Neighborhood Hits	269	Target Neighborhood Hits	140	Shared Neighborhood Hits	66
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	1.38821 (rank : 204)	NC score	0.165510 (rank : 236)
Query Neighborhood Hits	269	Target Neighborhood Hits	160	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

PEX2_MOUSE
θ value	1.38821 (rank : 205)	NC score	0.125765 (rank : 277)
Query Neighborhood Hits	269	Target Neighborhood Hits	57	Shared Neighborhood Hits	49
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

RNF13_MOUSE
θ value	1.38821 (rank : 206)	NC score	0.082947 (rank : 319)
Query Neighborhood Hits	269	Target Neighborhood Hits	164	Shared Neighborhood Hits	66
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TIF1A_HUMAN
θ value	1.38821 (rank : 207)	NC score	0.290263 (rank : 131)
Query Neighborhood Hits	269	Target Neighborhood Hits	327	Shared Neighborhood Hits	138
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

DCTN4_HUMAN
θ value	1.81305 (rank : 208)	NC score	0.035997 (rank : 438)
Query Neighborhood Hits	269	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

LTB1L_MOUSE
θ value	1.81305 (rank : 209)	NC score	0.011721 (rank : 444)
Query Neighborhood Hits	269	Target Neighborhood Hits	514	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.81305 (rank : 210)	NC score	0.011228 (rank : 445)
Query Neighborhood Hits	269	Target Neighborhood Hits	479	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MKRN3_HUMAN
θ value	1.81305 (rank : 211)	NC score	0.051649 (rank : 416)
Query Neighborhood Hits	269	Target Neighborhood Hits	165	Shared Neighborhood Hits	53
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

PEX2_HUMAN
θ value	1.81305 (rank : 212)	NC score	0.108464 (rank : 288)
Query Neighborhood Hits	269	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

RN133_HUMAN
θ value	1.81305 (rank : 213)	NC score	0.046750 (rank : 433)
Query Neighborhood Hits	269	Target Neighborhood Hits	108	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF4_HUMAN
θ value	1.81305 (rank : 214)	NC score	0.230995 (rank : 167)
Query Neighborhood Hits	269	Target Neighborhood Hits	212	Shared Neighborhood Hits	123
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	1.81305 (rank : 215)	NC score	0.229365 (rank : 170)
Query Neighborhood Hits	269	Target Neighborhood Hits	212	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TCF19_HUMAN
θ value	1.81305 (rank : 216)	NC score	0.106011 (rank : 293)
Query Neighborhood Hits	269	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

TIF1A_MOUSE
θ value	1.81305 (rank : 217)	NC score	0.282128 (rank : 140)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	132
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRAF4_MOUSE
θ value	1.81305 (rank : 218)	NC score	0.154117 (rank : 249)
Query Neighborhood Hits	269	Target Neighborhood Hits	338	Shared Neighborhood Hits	94
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

DTX3_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.188650 (rank : 211)
Query Neighborhood Hits	269	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	2.36792 (rank : 220)	NC score	0.193904 (rank : 202)
Query Neighborhood Hits	269	Target Neighborhood Hits	202	Shared Neighborhood Hits	124
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

PCLO_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.031567 (rank : 440)
Query Neighborhood Hits	269	Target Neighborhood Hits	2275	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RKHD1_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.127282 (rank : 276)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	58
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TRAF7_HUMAN
θ value	2.36792 (rank : 223)	NC score	0.114633 (rank : 286)
Query Neighborhood Hits	269	Target Neighborhood Hits	482	Shared Neighborhood Hits	141
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	2.36792 (rank : 224)	NC score	0.115643 (rank : 285)
Query Neighborhood Hits	269	Target Neighborhood Hits	470	Shared Neighborhood Hits	138
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI59_HUMAN
θ value	2.36792 (rank : 225)	NC score	0.318158 (rank : 90)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	154
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	2.36792 (rank : 226)	NC score	0.320219 (rank : 85)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	154
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI68_HUMAN
θ value	2.36792 (rank : 227)	NC score	0.278004 (rank : 143)
Query Neighborhood Hits	269	Target Neighborhood Hits	267	Shared Neighborhood Hits	147
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI73_HUMAN
θ value	2.36792 (rank : 228)	NC score	0.327182 (rank : 70)
Query Neighborhood Hits	269	Target Neighborhood Hits	258	Shared Neighborhood Hits	165
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM9_HUMAN
θ value	2.36792 (rank : 229)	NC score	0.240367 (rank : 164)
Query Neighborhood Hits	269	Target Neighborhood Hits	294	Shared Neighborhood Hits	133
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	2.36792 (rank : 230)	NC score	0.237255 (rank : 166)
Query Neighborhood Hits	269	Target Neighborhood Hits	274	Shared Neighborhood Hits	132
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

DTX3L_HUMAN
θ value	3.0926 (rank : 231)	NC score	0.136725 (rank : 269)
Query Neighborhood Hits	269	Target Neighborhood Hits	187	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

LNX1_HUMAN
θ value	3.0926 (rank : 232)	NC score	0.153681 (rank : 250)
Query Neighborhood Hits	269	Target Neighborhood Hits	379	Shared Neighborhood Hits	146
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PHF2_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.051139 (rank : 417)
Query Neighborhood Hits	269	Target Neighborhood Hits	208	Shared Neighborhood Hits	31
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.050481 (rank : 423)
Query Neighborhood Hits	269	Target Neighborhood Hits	241	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

TRI66_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.250513 (rank : 159)
Query Neighborhood Hits	269	Target Neighborhood Hits	479	Shared Neighborhood Hits	113
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

FHL2_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.012705 (rank : 443)
Query Neighborhood Hits	269	Target Neighborhood Hits	533	Shared Neighborhood Hits	16
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

LRSM1_HUMAN
θ value	4.03905 (rank : 237)	NC score	0.038698 (rank : 437)
Query Neighborhood Hits	269	Target Neighborhood Hits	1078	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PML_MOUSE
θ value	4.03905 (rank : 238)	NC score	0.165304 (rank : 237)
Query Neighborhood Hits	269	Target Neighborhood Hits	246	Shared Neighborhood Hits	104
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RD23B_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.046534 (rank : 434)
Query Neighborhood Hits	269	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

TRI49_HUMAN
θ value	4.03905 (rank : 240)	NC score	0.265597 (rank : 149)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI74_HUMAN
θ value	4.03905 (rank : 241)	NC score	0.319626 (rank : 87)
Query Neighborhood Hits	269	Target Neighborhood Hits	249	Shared Neighborhood Hits	161
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

UBD_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.077124 (rank : 334)
Query Neighborhood Hits	269	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P63072, Q9WV10	Gene names	Ubd, Fat10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

BIN1_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.008422 (rank : 447)
Query Neighborhood Hits	269	Target Neighborhood Hits	283	Shared Neighborhood Hits	6
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

ING1_MOUSE
θ value	5.27518 (rank : 244)	NC score	0.057871 (rank : 376)
Query Neighborhood Hits	269	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

JADE2_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.157458 (rank : 241)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.147907 (rank : 260)
Query Neighborhood Hits	269	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JHD1A_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.042940 (rank : 435)
Query Neighborhood Hits	269	Target Neighborhood Hits	133	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

PEX10_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.266361 (rank : 147)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	143
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRI48_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.266820 (rank : 146)
Query Neighborhood Hits	269	Target Neighborhood Hits	192	Shared Neighborhood Hits	138
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

FUBP1_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.008180 (rank : 448)
Query Neighborhood Hits	269	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

LNX1_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.143373 (rank : 266)
Query Neighborhood Hits	269	Target Neighborhood Hits	377	Shared Neighborhood Hits	139
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LTBP4_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.004760 (rank : 452)
Query Neighborhood Hits	269	Target Neighborhood Hits	607	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PRKN2_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.033686 (rank : 439)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

RAD18_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.174964 (rank : 227)
Query Neighborhood Hits	269	Target Neighborhood Hits	284	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RNF5_MOUSE
θ value	6.88961 (rank : 255)	NC score	0.205539 (rank : 191)
Query Neighborhood Hits	269	Target Neighborhood Hits	206	Shared Neighborhood Hits	119
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SPRE2_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.005808 (rank : 451)
Query Neighborhood Hits	269	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SRRM2_HUMAN
θ value	6.88961 (rank : 257)	NC score	0.019492 (rank : 442)
Query Neighborhood Hits	269	Target Neighborhood Hits	1296	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TIF1G_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.300344 (rank : 110)
Query Neighborhood Hits	269	Target Neighborhood Hits	410	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

CDCA5_MOUSE
θ value	8.99809 (rank : 259)	NC score	0.011003 (rank : 446)
Query Neighborhood Hits	269	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPY3, Q78HI6	Gene names	Cdca5
Domain Architecture	No domain graphic available
Description	Sororin (Cell division cycle-associated protein 5).

LTB1L_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.007696 (rank : 450)
Query Neighborhood Hits	269	Target Neighborhood Hits	553	Shared Neighborhood Hits	13
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.007865 (rank : 449)
Query Neighborhood Hits	269	Target Neighborhood Hits	502	Shared Neighborhood Hits	12
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MNAB_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.080563 (rank : 327)
Query Neighborhood Hits	269	Target Neighborhood Hits	196	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.081626 (rank : 322)
Query Neighborhood Hits	269	Target Neighborhood Hits	231	Shared Neighborhood Hits	90
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

PML_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.153254 (rank : 251)
Query Neighborhood Hits	269	Target Neighborhood Hits	248	Shared Neighborhood Hits	100
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PZRN4_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.132001 (rank : 270)
Query Neighborhood Hits	269	Target Neighborhood Hits	438	Shared Neighborhood Hits	142
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RNF26_HUMAN
θ value	8.99809 (rank : 266)	NC score	0.080925 (rank : 326)
Query Neighborhood Hits	269	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF5_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.207108 (rank : 190)
Query Neighborhood Hits	269	Target Neighborhood Hits	206	Shared Neighborhood Hits	121
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TIF1G_MOUSE
θ value	8.99809 (rank : 268)	NC score	0.297975 (rank : 115)
Query Neighborhood Hits	269	Target Neighborhood Hits	498	Shared Neighborhood Hits	156
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TLR12_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.000006 (rank : 453)
Query Neighborhood Hits	269	Target Neighborhood Hits	268	Shared Neighborhood Hits	3
SwissProt Accessions	Q6QNU9	Gene names	Tlr12
Domain Architecture	No domain graphic available
Description	Toll-like receptor 12 precursor.

AF10_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.091595 (rank : 306)
Query Neighborhood Hits	269	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.091462 (rank : 307)
Query Neighborhood Hits	269	Target Neighborhood Hits	182	Shared Neighborhood Hits	45
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.097982 (rank : 298)
Query Neighborhood Hits	269	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AMFR2_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.096413 (rank : 300)
Query Neighborhood Hits	269	Target Neighborhood Hits	219	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.090598 (rank : 309)
Query Neighborhood Hits	269	Target Neighborhood Hits	208	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARD1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.066900 (rank : 349)
Query Neighborhood Hits	269	Target Neighborhood Hits	621	Shared Neighborhood Hits	71
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.070126 (rank : 343)
Query Neighborhood Hits	269	Target Neighborhood Hits	573	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

ATRX_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.054532 (rank : 400)
Query Neighborhood Hits	269	Target Neighborhood Hits	842	Shared Neighborhood Hits	46
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.058961 (rank : 370)
Query Neighborhood Hits	269	Target Neighborhood Hits	682	Shared Neighborhood Hits	40
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BARD1_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.058388 (rank : 373)
Query Neighborhood Hits	269	Target Neighborhood Hits	427	Shared Neighborhood Hits	92
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.057363 (rank : 382)
Query Neighborhood Hits	269	Target Neighborhood Hits	411	Shared Neighborhood Hits	89
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BIRC7_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.128715 (rank : 274)
Query Neighborhood Hits	269	Target Neighborhood Hits	185	Shared Neighborhood Hits	120
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.064097 (rank : 352)
Query Neighborhood Hits	269	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BRD2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.058996 (rank : 369)
Query Neighborhood Hits	269	Target Neighborhood Hits	242	Shared Neighborhood Hits	27
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.052532 (rank : 411)
Query Neighborhood Hits	269	Target Neighborhood Hits	369	Shared Neighborhood Hits	19
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.051802 (rank : 415)
Query Neighborhood Hits	269	Target Neighborhood Hits	402	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.057347 (rank : 383)
Query Neighborhood Hits	269	Target Neighborhood Hits	851	Shared Neighborhood Hits	35
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.056264 (rank : 392)
Query Neighborhood Hits	269	Target Neighborhood Hits	845	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD7_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.050488 (rank : 421)
Query Neighborhood Hits	269	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.050281 (rank : 426)
Query Neighborhood Hits	269	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.066554 (rank : 350)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.063040 (rank : 355)
Query Neighborhood Hits	269	Target Neighborhood Hits	422	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD9_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.056409 (rank : 390)
Query Neighborhood Hits	269	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.056396 (rank : 391)
Query Neighborhood Hits	269	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRDT_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.050134 (rank : 429)
Query Neighborhood Hits	269	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BSPRY_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.174362 (rank : 229)
Query Neighborhood Hits	269	Target Neighborhood Hits	115	Shared Neighborhood Hits	63
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.180766 (rank : 221)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.151370 (rank : 254)
Query Neighborhood Hits	269	Target Neighborhood Hits	322	Shared Neighborhood Hits	56
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.153036 (rank : 252)
Query Neighborhood Hits	269	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.143298 (rank : 267)
Query Neighborhood Hits	269	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.149468 (rank : 258)
Query Neighborhood Hits	269	Target Neighborhood Hits	191	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.144462 (rank : 263)
Query Neighborhood Hits	269	Target Neighborhood Hits	195	Shared Neighborhood Hits	52
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.149609 (rank : 257)
Query Neighborhood Hits	269	Target Neighborhood Hits	229	Shared Neighborhood Hits	56
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.151258 (rank : 255)
Query Neighborhood Hits	269	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.146530 (rank : 262)
Query Neighborhood Hits	269	Target Neighborhood Hits	143	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.140809 (rank : 268)
Query Neighborhood Hits	269	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.149733 (rank : 256)
Query Neighborhood Hits	269	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CBLB_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.079281 (rank : 331)
Query Neighborhood Hits	269	Target Neighborhood Hits	261	Shared Neighborhood Hits	116
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.080053 (rank : 329)
Query Neighborhood Hits	269	Target Neighborhood Hits	277	Shared Neighborhood Hits	116
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.082339 (rank : 321)
Query Neighborhood Hits	269	Target Neighborhood Hits	173	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.082722 (rank : 320)
Query Neighborhood Hits	269	Target Neighborhood Hits	186	Shared Neighborhood Hits	102
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.081271 (rank : 325)
Query Neighborhood Hits	269	Target Neighborhood Hits	353	Shared Neighborhood Hits	124
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.084989 (rank : 316)
Query Neighborhood Hits	269	Target Neighborhood Hits	426	Shared Neighborhood Hits	129
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CECR2_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.077158 (rank : 333)
Query Neighborhood Hits	269	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.057395 (rank : 381)
Query Neighborhood Hits	269	Target Neighborhood Hits	337	Shared Neighborhood Hits	15
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.057537 (rank : 379)
Query Neighborhood Hits	269	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.059705 (rank : 365)
Query Neighborhood Hits	269	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.059962 (rank : 362)
Query Neighborhood Hits	269	Target Neighborhood Hits	342	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.057313 (rank : 384)
Query Neighborhood Hits	269	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.057443 (rank : 380)
Query Neighborhood Hits	269	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.057609 (rank : 377)
Query Neighborhood Hits	269	Target Neighborhood Hits	427	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CM007_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.104575 (rank : 295)
Query Neighborhood Hits	269	Target Neighborhood Hits	422	Shared Neighborhood Hits	98
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.118833 (rank : 283)
Query Neighborhood Hits	269	Target Neighborhood Hits	416	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CXCC1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.100482 (rank : 297)
Query Neighborhood Hits	269	Target Neighborhood Hits	143	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.093642 (rank : 302)
Query Neighborhood Hits	269	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DPF3_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.090760 (rank : 308)
Query Neighborhood Hits	269	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

DPF3_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.106786 (rank : 292)
Query Neighborhood Hits	269	Target Neighborhood Hits	327	Shared Neighborhood Hits	12
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

EP300_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.050486 (rank : 422)
Query Neighborhood Hits	269	Target Neighborhood Hits	821	Shared Neighborhood Hits	38
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERCC6_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.054366 (rank : 402)
Query Neighborhood Hits	269	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

ERMAP_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.170740 (rank : 233)
Query Neighborhood Hits	269	Target Neighborhood Hits	155	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.157326 (rank : 243)
Query Neighborhood Hits	269	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

EZH1_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.050180 (rank : 428)
Query Neighborhood Hits	269	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.050112 (rank : 430)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FSD1L_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.080449 (rank : 328)
Query Neighborhood Hits	269	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.087418 (rank : 313)
Query Neighborhood Hits	269	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GCNL2_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.063153 (rank : 354)
Query Neighborhood Hits	269	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.063697 (rank : 353)
Query Neighborhood Hits	269	Target Neighborhood Hits	146	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

ING1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.050319 (rank : 425)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING3_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.050972 (rank : 418)
Query Neighborhood Hits	269	Target Neighborhood Hits	178	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING5_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.058007 (rank : 375)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.055904 (rank : 394)
Query Neighborhood Hits	269	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

JARD2_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.069750 (rank : 344)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.067138 (rank : 346)
Query Neighborhood Hits	269	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3A_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.092372 (rank : 304)
Query Neighborhood Hits	269	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.094563 (rank : 301)
Query Neighborhood Hits	269	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.089238 (rank : 312)
Query Neighborhood Hits	269	Target Neighborhood Hits	128	Shared Neighborhood Hits	30
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.090250 (rank : 310)
Query Neighborhood Hits	269	Target Neighborhood Hits	152	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.090034 (rank : 311)
Query Neighborhood Hits	269	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3C_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.092548 (rank : 303)
Query Neighborhood Hits	269	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3D_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.056157 (rank : 393)
Query Neighborhood Hits	269	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.056915 (rank : 387)
Query Neighborhood Hits	269	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

LY10_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.157311 (rank : 244)
Query Neighborhood Hits	269	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MAT1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.054727 (rank : 399)
Query Neighborhood Hits	269	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.053308 (rank : 409)
Query Neighborhood Hits	269	Target Neighborhood Hits	217	Shared Neighborhood Hits	40
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MEFV_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.202040 (rank : 196)
Query Neighborhood Hits	269	Target Neighborhood Hits	431	Shared Neighborhood Hits	87
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.196540 (rank : 200)
Query Neighborhood Hits	269	Target Neighborhood Hits	236	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MGRN1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.059258 (rank : 367)
Query Neighborhood Hits	269	Target Neighborhood Hits	192	Shared Neighborhood Hits	76
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.057596 (rank : 378)
Query Neighborhood Hits	269	Target Neighborhood Hits	149	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MYST1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.059986 (rank : 359)
Query Neighborhood Hits	269	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.059932 (rank : 363)
Query Neighborhood Hits	269	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

MYST2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.060802 (rank : 356)
Query Neighborhood Hits	269	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.060461 (rank : 357)
Query Neighborhood Hits	269	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

NHLC1_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.073707 (rank : 338)
Query Neighborhood Hits	269	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.083256 (rank : 318)
Query Neighborhood Hits	269	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCAF_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.067112 (rank : 347)
Query Neighborhood Hits	269	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PHF11_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.072631 (rank : 339)
Query Neighborhood Hits	269	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF1_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.107927 (rank : 289)
Query Neighborhood Hits	269	Target Neighborhood Hits	117	Shared Neighborhood Hits	54
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.107476 (rank : 291)
Query Neighborhood Hits	269	Target Neighborhood Hits	116	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF20_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.059340 (rank : 366)
Query Neighborhood Hits	269	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.058146 (rank : 374)
Query Neighborhood Hits	269	Target Neighborhood Hits	513	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF22_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.071646 (rank : 341)
Query Neighborhood Hits	269	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.076956 (rank : 336)
Query Neighborhood Hits	269	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF6_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.054147 (rank : 404)
Query Neighborhood Hits	269	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.052262 (rank : 412)
Query Neighborhood Hits	269	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.056926 (rank : 385)
Query Neighborhood Hits	269	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.053520 (rank : 407)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PJA1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.050190 (rank : 427)
Query Neighborhood Hits	269	Target Neighborhood Hits	159	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RA54B_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.050051 (rank : 432)
Query Neighborhood Hits	269	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD18_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.173054 (rank : 230)
Query Neighborhood Hits	269	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAD54_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.050576 (rank : 420)
Query Neighborhood Hits	269	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RBBP6_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.107529 (rank : 290)
Query Neighborhood Hits	269	Target Neighborhood Hits	1135	Shared Neighborhood Hits	141
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.113392 (rank : 287)
Query Neighborhood Hits	269	Target Neighborhood Hits	1014	Shared Neighborhood Hits	133
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.086094 (rank : 314)
Query Neighborhood Hits	269	Target Neighborhood Hits	433	Shared Neighborhood Hits	111
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.091604 (rank : 305)
Query Neighborhood Hits	269	Target Neighborhood Hits	244	Shared Neighborhood Hits	105
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFFL_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.060170 (rank : 358)
Query Neighborhood Hits	269	Target Neighborhood Hits	175	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.058959 (rank : 371)
Query Neighborhood Hits	269	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFPL1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.178689 (rank : 224)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.179053 (rank : 223)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.185939 (rank : 214)
Query Neighborhood Hits	269	Target Neighborhood Hits	134	Shared Neighborhood Hits	90
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RN123_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.051958 (rank : 413)
Query Neighborhood Hits	269	Target Neighborhood Hits	175	Shared Neighborhood Hits	88
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.051863 (rank : 414)
Query Neighborhood Hits	269	Target Neighborhood Hits	174	Shared Neighborhood Hits	89
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN141_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.143598 (rank : 265)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.143824 (rank : 264)
Query Neighborhood Hits	269	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.157417 (rank : 242)
Query Neighborhood Hits	269	Target Neighborhood Hits	162	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.156402 (rank : 246)
Query Neighborhood Hits	269	Target Neighborhood Hits	161	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.077123 (rank : 335)
Query Neighborhood Hits	269	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.081518 (rank : 323)
Query Neighborhood Hits	269	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN167_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.067074 (rank : 348)
Query Neighborhood Hits	269	Target Neighborhood Hits	157	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.069426 (rank : 345)
Query Neighborhood Hits	269	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN183_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.149276 (rank : 259)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.129077 (rank : 273)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	89
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.191830 (rank : 206)
Query Neighborhood Hits	269	Target Neighborhood Hits	213	Shared Neighborhood Hits	123
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.190769 (rank : 210)
Query Neighborhood Hits	269	Target Neighborhood Hits	211	Shared Neighborhood Hits	123
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.055096 (rank : 397)
Query Neighborhood Hits	269	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.050440 (rank : 424)
Query Neighborhood Hits	269	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF41_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.211850 (rank : 184)
Query Neighborhood Hits	269	Target Neighborhood Hits	226	Shared Neighborhood Hits	135
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.211551 (rank : 185)
Query Neighborhood Hits	269	Target Neighborhood Hits	224	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SET1A_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.070868 (rank : 342)
Query Neighborhood Hits	269	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD2_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.059181 (rank : 368)
Query Neighborhood Hits	269	Target Neighborhood Hits	412	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETD8_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.056562 (rank : 389)
Query Neighborhood Hits	269	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.055871 (rank : 395)
Query Neighborhood Hits	269	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SMAL1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.050053 (rank : 431)
Query Neighborhood Hits	269	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.054744 (rank : 398)
Query Neighborhood Hits	269	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.054462 (rank : 401)
Query Neighborhood Hits	269	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.074053 (rank : 337)
Query Neighborhood Hits	269	Target Neighborhood Hits	503	Shared Neighborhood Hits	31
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.072624 (rank : 340)
Query Neighborhood Hits	269	Target Neighborhood Hits	597	Shared Neighborhood Hits	31
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA5_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.053752 (rank : 406)
Query Neighborhood Hits	269	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.053839 (rank : 405)
Query Neighborhood Hits	269	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRCD_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.052881 (rank : 410)
Query Neighborhood Hits	269	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.053518 (rank : 408)
Query Neighborhood Hits	269	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SP110_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.121878 (rank : 281)
Query Neighborhood Hits	269	Target Neighborhood Hits	141	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SPRY4_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.147000 (rank : 261)
Query Neighborhood Hits	269	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.152860 (rank : 253)
Query Neighborhood Hits	269	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TAF1L_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.056770 (rank : 388)
Query Neighborhood Hits	269	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.058558 (rank : 372)
Query Neighborhood Hits	269	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TIP60_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.059982 (rank : 360)
Query Neighborhood Hits	269	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.059971 (rank : 361)
Query Neighborhood Hits	269	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TOPRS_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.122979 (rank : 280)
Query Neighborhood Hits	269	Target Neighborhood Hits	286	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.125548 (rank : 279)
Query Neighborhood Hits	269	Target Neighborhood Hits	263	Shared Neighborhood Hits	98
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.079035 (rank : 332)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRAF1_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.079759 (rank : 330)
Query Neighborhood Hits	269	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TRAIP_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.065816 (rank : 351)
Query Neighborhood Hits	269	Target Neighborhood Hits	780	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.056916 (rank : 386)
Query Neighborhood Hits	269	Target Neighborhood Hits	745	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI14_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.200493 (rank : 199)
Query Neighborhood Hits	269	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.201780 (rank : 197)
Query Neighborhood Hits	269	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI15_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.254450 (rank : 157)
Query Neighborhood Hits	269	Target Neighborhood Hits	395	Shared Neighborhood Hits	143
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI16_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.181509 (rank : 218)
Query Neighborhood Hits	269	Target Neighborhood Hits	231	Shared Neighborhood Hits	73
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.192789 (rank : 204)
Query Neighborhood Hits	269	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.181371 (rank : 219)
Query Neighborhood Hits	269	Target Neighborhood Hits	273	Shared Neighborhood Hits	77
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.181200 (rank : 220)
Query Neighborhood Hits	269	Target Neighborhood Hits	306	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI32_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.243643 (rank : 161)
Query Neighborhood Hits	269	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.242172 (rank : 162)
Query Neighborhood Hits	269	Target Neighborhood Hits	271	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI37_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.214010 (rank : 180)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	131
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.213558 (rank : 181)
Query Neighborhood Hits	269	Target Neighborhood Hits	316	Shared Neighborhood Hits	130
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.166472 (rank : 234)
Query Neighborhood Hits	269	Target Neighborhood Hits	283	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.171125 (rank : 232)
Query Neighborhood Hits	269	Target Neighborhood Hits	316	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.174592 (rank : 228)
Query Neighborhood Hits	269	Target Neighborhood Hits	393	Shared Neighborhood Hits	74
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.176677 (rank : 225)
Query Neighborhood Hits	269	Target Neighborhood Hits	327	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.158871 (rank : 240)
Query Neighborhood Hits	269	Target Neighborhood Hits	155	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.154767 (rank : 248)
Query Neighborhood Hits	269	Target Neighborhood Hits	155	Shared Neighborhood Hits	85
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

UB7I3_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.050891 (rank : 419)
Query Neighborhood Hits	269	Target Neighborhood Hits	136	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.059736 (rank : 364)
Query Neighborhood Hits	269	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UCRP_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.054157 (rank : 403)
Query Neighborhood Hits	269	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q64339, Q8K0H3	Gene names	Isg15, G1p2, Ucrp
Domain Architecture
Description	Ubiquitin cross-reactive protein precursor (Interferon-stimulated protein 15) (IP17).

ZN179_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.250283 (rank : 160)
Query Neighborhood Hits	269	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

Hits sorted by NC score

UHRF2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	269	Target Neighborhood Hits	269	Shared Neighborhood Hits	269
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.994662 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	269	Target Neighborhood Hits	275	Shared Neighborhood Hits	253
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

UHRF1_HUMAN
NC score	0.965771 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	269	Target Neighborhood Hits	272	Shared Neighborhood Hits	226
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
NC score	0.965244 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	269	Target Neighborhood Hits	278	Shared Neighborhood Hits	224
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RN125_HUMAN
NC score	0.412523 (rank : 5)	θ value	1.09739e-05 (rank : 30)
Query Neighborhood Hits	269	Target Neighborhood Hits	230	Shared Neighborhood Hits	152
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

BAZ1B_MOUSE
NC score	0.409908 (rank : 6)	θ value	2.79066e-09 (rank : 6)
Query Neighborhood Hits	269	Target Neighborhood Hits	394	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

DPF1_HUMAN
NC score	0.405824 (rank : 7)	θ value	4.1701e-05 (rank : 37)
Query Neighborhood Hits	269	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

RSF1_HUMAN
NC score	0.401849 (rank : 8)	θ value	5.26297e-08 (rank : 13)
Query Neighborhood Hits	269	Target Neighborhood Hits	539	Shared Neighborhood Hits	77
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PHF10_MOUSE
NC score	0.399266 (rank : 9)	θ value	0.000121331 (rank : 49)
Query Neighborhood Hits	269	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF10_HUMAN
NC score	0.397676 (rank : 10)	θ value	0.000121331 (rank : 48)
Query Neighborhood Hits	269	Target Neighborhood Hits	151	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PF21A_MOUSE
NC score	0.395471 (rank : 11)	θ value	7.1131e-05 (rank : 40)
Query Neighborhood Hits	269	Target Neighborhood Hits	285	Shared Neighborhood Hits	77
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

AIRE_HUMAN
NC score	0.394914 (rank : 12)	θ value	0.00228821 (rank : 82)
Query Neighborhood Hits	269	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PF21A_HUMAN
NC score	0.393215 (rank : 13)	θ value	5.44631e-05 (rank : 39)
Query Neighborhood Hits	269	Target Neighborhood Hits	303	Shared Neighborhood Hits	79
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TRI31_HUMAN
NC score	0.391173 (rank : 14)	θ value	6.43352e-06 (rank : 27)
Query Neighborhood Hits	269	Target Neighborhood Hits	299	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

DPF1_MOUSE
NC score	0.388359 (rank : 15)	θ value	4.45536e-07 (rank : 17)
Query Neighborhood Hits	269	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

RN125_MOUSE
NC score	0.386932 (rank : 16)	θ value	0.000461057 (rank : 62)
Query Neighborhood Hits	269	Target Neighborhood Hits	220	Shared Neighborhood Hits	143
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

BAZ1B_HUMAN
NC score	0.386661 (rank : 17)	θ value	2.79066e-09 (rank : 5)
Query Neighborhood Hits	269	Target Neighborhood Hits	701	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

REQU_HUMAN
NC score	0.380613 (rank : 18)	θ value	4.92598e-06 (rank : 25)
Query Neighborhood Hits	269	Target Neighborhood Hits	523	Shared Neighborhood Hits	73
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.379446 (rank : 19)	θ value	8.40245e-06 (rank : 28)
Query Neighborhood Hits	269	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RING1_HUMAN
NC score	0.377969 (rank : 20)	θ value	0.000121331 (rank : 50)
Query Neighborhood Hits	269	Target Neighborhood Hits	219	Shared Neighborhood Hits	132
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RN168_HUMAN
NC score	0.374891 (rank : 21)	θ value	0.000461057 (rank : 63)
Query Neighborhood Hits	269	Target Neighborhood Hits	370	Shared Neighborhood Hits	144
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RING1_MOUSE
NC score	0.373493 (rank : 22)	θ value	0.000121331 (rank : 51)
Query Neighborhood Hits	269	Target Neighborhood Hits	220	Shared Neighborhood Hits	132
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI12_MOUSE
NC score	0.373437 (rank : 23)	θ value	7.1131e-05 (rank : 41)
Query Neighborhood Hits	269	Target Neighborhood Hits	387	Shared Neighborhood Hits	159
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

AIRE_MOUSE
NC score	0.373163 (rank : 24)	θ value	0.00175202 (rank : 80)
Query Neighborhood Hits	269	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
NC score	0.367767 (rank : 25)	θ value	7.59969e-07 (rank : 21)
Query Neighborhood Hits	269	Target Neighborhood Hits	693	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

TRI13_HUMAN
NC score	0.363159 (rank : 26)	θ value	0.00869519 (rank : 112)
Query Neighborhood Hits	269	Target Neighborhood Hits	274	Shared Neighborhood Hits	158
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI65_HUMAN
NC score	0.363147 (rank : 27)	θ value	0.00509761 (rank : 108)
Query Neighborhood Hits	269	Target Neighborhood Hits	330	Shared Neighborhood Hits	166
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI13_MOUSE
NC score	0.363097 (rank : 28)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	269	Target Neighborhood Hits	282	Shared Neighborhood Hits	159
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

RING2_MOUSE
NC score	0.362898 (rank : 29)	θ value	0.00020696 (rank : 57)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	132
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.362846 (rank : 30)	θ value	0.00020696 (rank : 56)
Query Neighborhood Hits	269	Target Neighborhood Hits	201	Shared Neighborhood Hits	132
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

TRI25_MOUSE
NC score	0.360090 (rank : 31)	θ value	7.1131e-05 (rank : 43)
Query Neighborhood Hits	269	Target Neighborhood Hits	446	Shared Neighborhood Hits	160
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI65_MOUSE
NC score	0.360008 (rank : 32)	θ value	0.00134147 (rank : 79)
Query Neighborhood Hits	269	Target Neighborhood Hits	340	Shared Neighborhood Hits	167
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

PF21B_MOUSE
NC score	0.351195 (rank : 33)	θ value	0.000786445 (rank : 72)
Query Neighborhood Hits	269	Target Neighborhood Hits	278	Shared Neighborhood Hits	71
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TRI63_MOUSE
NC score	0.350559 (rank : 34)	θ value	0.00020696 (rank : 58)
Query Neighborhood Hits	269	Target Neighborhood Hits	240	Shared Neighborhood Hits	131
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

RN166_MOUSE
NC score	0.349842 (rank : 35)	θ value	0.0113563 (rank : 120)
Query Neighborhood Hits	269	Target Neighborhood Hits	248	Shared Neighborhood Hits	146
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI54_HUMAN
NC score	0.349357 (rank : 36)	θ value	0.00228821 (rank : 85)
Query Neighborhood Hits	269	Target Neighborhood Hits	209	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

PF21B_HUMAN
NC score	0.347687 (rank : 37)	θ value	0.00390308 (rank : 95)
Query Neighborhood Hits	269	Target Neighborhood Hits	197	Shared Neighborhood Hits	67
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TRI54_MOUSE
NC score	0.347577 (rank : 38)	θ value	0.00228821 (rank : 86)
Query Neighborhood Hits	269	Target Neighborhood Hits	197	Shared Neighborhood Hits	129
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI63_HUMAN
NC score	0.347369 (rank : 39)	θ value	0.000158464 (rank : 54)
Query Neighborhood Hits	269	Target Neighborhood Hits	298	Shared Neighborhood Hits	131
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

RN166_HUMAN
NC score	0.345943 (rank : 40)	θ value	0.0252991 (rank : 133)
Query Neighborhood Hits	269	Target Neighborhood Hits	240	Shared Neighborhood Hits	147
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_MOUSE
NC score	0.345098 (rank : 41)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	269	Target Neighborhood Hits	440	Shared Neighborhood Hits	141
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN313_MOUSE
NC score	0.343453 (rank : 42)	θ value	0.0563607 (rank : 150)
Query Neighborhood Hits	269	Target Neighborhood Hits	273	Shared Neighborhood Hits	157
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

JAD1A_HUMAN
NC score	0.343419 (rank : 43)	θ value	2.21117e-06 (rank : 22)
Query Neighborhood Hits	269	Target Neighborhood Hits	328	Shared Neighborhood Hits	75
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

BFAR_HUMAN
NC score	0.343205 (rank : 44)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	269	Target Neighborhood Hits	222	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI35_HUMAN
NC score	0.342341 (rank : 45)	θ value	0.00102713 (rank : 74)
Query Neighborhood Hits	269	Target Neighborhood Hits	382	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRIM8_HUMAN
NC score	0.342295 (rank : 46)	θ value	0.0431538 (rank : 145)
Query Neighborhood Hits	269	Target Neighborhood Hits	650	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BRCA1_HUMAN
NC score	0.341420 (rank : 47)	θ value	0.000461057 (rank : 61)
Query Neighborhood Hits	269	Target Neighborhood Hits	381	Shared Neighborhood Hits	154
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI55_HUMAN
NC score	0.341364 (rank : 48)	θ value	0.00390308 (rank : 102)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI40_HUMAN
NC score	0.341272 (rank : 49)	θ value	0.0961366 (rank : 164)
Query Neighborhood Hits	269	Target Neighborhood Hits	279	Shared Neighborhood Hits	157
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM8_MOUSE
NC score	0.340207 (rank : 50)	θ value	0.0431538 (rank : 146)
Query Neighborhood Hits	269	Target Neighborhood Hits	674	Shared Neighborhood Hits	159
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM4_HUMAN
NC score	0.340013 (rank : 51)	θ value	0.000158464 (rank : 55)
Query Neighborhood Hits	269	Target Neighborhood Hits	321	Shared Neighborhood Hits	159
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

JAD1C_MOUSE
NC score	0.339949 (rank : 52)	θ value	5.81887e-07 (rank : 20)
Query Neighborhood Hits	269	Target Neighborhood Hits	164	Shared Neighborhood Hits	70
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

TRI25_HUMAN
NC score	0.339469 (rank : 53)	θ value	0.00134147 (rank : 77)
Query Neighborhood Hits	269	Target Neighborhood Hits	472	Shared Neighborhood Hits	162
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

JAD1C_HUMAN
NC score	0.339389 (rank : 54)	θ value	5.81887e-07 (rank : 19)
Query Neighborhood Hits	269	Target Neighborhood Hits	187	Shared Neighborhood Hits	70
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

RNF8_MOUSE
NC score	0.339086 (rank : 55)	θ value	1.09739e-05 (rank : 31)
Query Neighborhood Hits	269	Target Neighborhood Hits	618	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

JAD1D_HUMAN
NC score	0.338982 (rank : 56)	θ value	2.88788e-06 (rank : 23)
Query Neighborhood Hits	269	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PHF14_MOUSE
NC score	0.338851 (rank : 57)	θ value	1.38499e-08 (rank : 11)
Query Neighborhood Hits	269	Target Neighborhood Hits	342	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

ZN313_HUMAN
NC score	0.337695 (rank : 58)	θ value	0.0563607 (rank : 149)
Query Neighborhood Hits	269	Target Neighborhood Hits	264	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

BFAR_MOUSE
NC score	0.337211 (rank : 59)	θ value	0.0193708 (rank : 126)
Query Neighborhood Hits	269	Target Neighborhood Hits	232	Shared Neighborhood Hits	137
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

PHF12_MOUSE
NC score	0.336699 (rank : 60)	θ value	0.00175202 (rank : 81)
Query Neighborhood Hits	269	Target Neighborhood Hits	172	Shared Neighborhood Hits	73
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TRI35_MOUSE
NC score	0.336665 (rank : 61)	θ value	0.00509761 (rank : 107)
Query Neighborhood Hits	269	Target Neighborhood Hits	465	Shared Neighborhood Hits	170
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

JAD1D_MOUSE
NC score	0.335904 (rank : 62)	θ value	2.61198e-07 (rank : 16)
Query Neighborhood Hits	269	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

TRI30_MOUSE
NC score	0.334922 (rank : 63)	θ value	0.00869519 (rank : 115)
Query Neighborhood Hits	269	Target Neighborhood Hits	434	Shared Neighborhood Hits	161
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

BRCA1_MOUSE
NC score	0.334579 (rank : 64)	θ value	0.00134147 (rank : 75)
Query Neighborhood Hits	269	Target Neighborhood Hits	436	Shared Neighborhood Hits	161
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

PHF12_HUMAN
NC score	0.333704 (rank : 65)	θ value	0.00390308 (rank : 96)
Query Neighborhood Hits	269	Target Neighborhood Hits	174	Shared Neighborhood Hits	73
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TRI60_HUMAN
NC score	0.332553 (rank : 66)	θ value	9.29e-05 (rank : 45)
Query Neighborhood Hits	269	Target Neighborhood Hits	357	Shared Neighborhood Hits	163
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

PHF14_HUMAN
NC score	0.332375 (rank : 67)	θ value	1.06045e-08 (rank : 8)
Query Neighborhood Hits	269	Target Neighborhood Hits	447	Shared Neighborhood Hits	81
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

RAG1_HUMAN
NC score	0.330903 (rank : 68)	θ value	0.000602161 (rank : 66)
Query Neighborhood Hits	269	Target Neighborhood Hits	203	Shared Neighborhood Hits	129
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RNF8_HUMAN
NC score	0.329134 (rank : 69)	θ value	8.40245e-06 (rank : 29)
Query Neighborhood Hits	269	Target Neighborhood Hits	622	Shared Neighborhood Hits	157
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI73_HUMAN
NC score	0.327182 (rank : 70)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	269	Target Neighborhood Hits	258	Shared Neighborhood Hits	165
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI17_HUMAN
NC score	0.326876 (rank : 71)	θ value	7.1131e-05 (rank : 42)
Query Neighborhood Hits	269	Target Neighborhood Hits	318	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM5_HUMAN
NC score	0.326845 (rank : 72)	θ value	0.00228821 (rank : 88)
Query Neighborhood Hits	269	Target Neighborhood Hits	424	Shared Neighborhood Hits	162
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI11_MOUSE
NC score	0.326334 (rank : 73)	θ value	0.000121331 (rank : 53)
Query Neighborhood Hits	269	Target Neighborhood Hits	329	Shared Neighborhood Hits	166
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

RAG1_MOUSE
NC score	0.326045 (rank : 74)	θ value	0.00102713 (rank : 73)
Query Neighborhood Hits	269	Target Neighborhood Hits	189	Shared Neighborhood Hits	131
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TIF1B_MOUSE
NC score	0.325259 (rank : 75)	θ value	0.00665767 (rank : 109)
Query Neighborhood Hits	269	Target Neighborhood Hits	276	Shared Neighborhood Hits	131
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI11_HUMAN
NC score	0.324765 (rank : 76)	θ value	0.000121331 (rank : 52)
Query Neighborhood Hits	269	Target Neighborhood Hits	316	Shared Neighborhood Hits	162
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI52_HUMAN
NC score	0.324471 (rank : 77)	θ value	0.47712 (rank : 185)
Query Neighborhood Hits	269	Target Neighborhood Hits	213	Shared Neighborhood Hits	150
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TIF1B_HUMAN
NC score	0.322479 (rank : 78)	θ value	0.00390308 (rank : 98)
Query Neighborhood Hits	269	Target Neighborhood Hits	312	Shared Neighborhood Hits	134
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

MLL3_MOUSE
NC score	0.322410 (rank : 79)	θ value	1.38499e-08 (rank : 10)
Query Neighborhood Hits	269	Target Neighborhood Hits	1399	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TRI43_HUMAN
NC score	0.322176 (rank : 80)	θ value	0.0148317 (rank : 125)
Query Neighborhood Hits	269	Target Neighborhood Hits	341	Shared Neighborhood Hits	158
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI22_HUMAN
NC score	0.321731 (rank : 81)	θ value	0.00869519 (rank : 114)
Query Neighborhood Hits	269	Target Neighborhood Hits	396	Shared Neighborhood Hits	163
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

MLL2_HUMAN
NC score	0.321643 (rank : 82)	θ value	1.80886e-08 (rank : 12)
Query Neighborhood Hits	269	Target Neighborhood Hits	1788	Shared Neighborhood Hits	110
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TRI50_MOUSE
NC score	0.321104 (rank : 83)	θ value	0.00869519 (rank : 116)
Query Neighborhood Hits	269	Target Neighborhood Hits	326	Shared Neighborhood Hits	166
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI26_HUMAN
NC score	0.320803 (rank : 84)	θ value	0.125558 (rank : 168)
Query Neighborhood Hits	269	Target Neighborhood Hits	335	Shared Neighborhood Hits	163
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI59_MOUSE
NC score	0.320219 (rank : 85)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	154
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

MYST4_MOUSE
NC score	0.319859 (rank : 86)	θ value	4.1701e-05 (rank : 38)
Query Neighborhood Hits	269	Target Neighborhood Hits	416	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

TRI74_HUMAN
NC score	0.319626 (rank : 87)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	269	Target Neighborhood Hits	249	Shared Neighborhood Hits	161
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI26_MOUSE
NC score	0.319499 (rank : 88)	θ value	0.0961366 (rank : 163)
Query Neighborhood Hits	269	Target Neighborhood Hits	339	Shared Neighborhood Hits	163
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI56_HUMAN
NC score	0.318684 (rank : 89)	θ value	0.00228821 (rank : 87)
Query Neighborhood Hits	269	Target Neighborhood Hits	339	Shared Neighborhood Hits	158
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI59_HUMAN
NC score	0.318158 (rank : 90)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	154
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI17_MOUSE
NC score	0.317764 (rank : 91)	θ value	0.000270298 (rank : 59)
Query Neighborhood Hits	269	Target Neighborhood Hits	620	Shared Neighborhood Hits	167
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI56_MOUSE
NC score	0.317198 (rank : 92)	θ value	0.000602161 (rank : 69)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	150
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

BAZ2A_HUMAN
NC score	0.316394 (rank : 93)	θ value	1.87187e-05 (rank : 34)
Query Neighborhood Hits	269	Target Neighborhood Hits	780	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
NC score	0.315706 (rank : 94)	θ value	6.43352e-06 (rank : 26)
Query Neighborhood Hits	269	Target Neighborhood Hits	744	Shared Neighborhood Hits	77
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST4_HUMAN
NC score	0.313318 (rank : 95)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	269	Target Neighborhood Hits	671	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TRI39_HUMAN
NC score	0.313257 (rank : 96)	θ value	0.000461057 (rank : 64)
Query Neighborhood Hits	269	Target Neighborhood Hits	693	Shared Neighborhood Hits	165
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI34_HUMAN
NC score	0.312366 (rank : 97)	θ value	0.0193708 (rank : 130)
Query Neighborhood Hits	269	Target Neighborhood Hits	416	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI39_MOUSE
NC score	0.312324 (rank : 98)	θ value	0.000461057 (rank : 65)
Query Neighborhood Hits	269	Target Neighborhood Hits	691	Shared Neighborhood Hits	168
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI50_HUMAN
NC score	0.312227 (rank : 99)	θ value	0.0736092 (rank : 154)
Query Neighborhood Hits	269	Target Neighborhood Hits	294	Shared Neighborhood Hits	164
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RO52_MOUSE
NC score	0.311161 (rank : 100)	θ value	0.00390308 (rank : 97)
Query Neighborhood Hits	269	Target Neighborhood Hits	360	Shared Neighborhood Hits	162
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI10_MOUSE
NC score	0.309601 (rank : 101)	θ value	0.0113563 (rank : 122)
Query Neighborhood Hits	269	Target Neighborhood Hits	285	Shared Neighborhood Hits	157
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

RO52_HUMAN
NC score	0.305690 (rank : 102)	θ value	0.0193708 (rank : 127)
Query Neighborhood Hits	269	Target Neighborhood Hits	419	Shared Neighborhood Hits	165
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

MLL3_HUMAN
NC score	0.305230 (rank : 103)	θ value	1.38499e-08 (rank : 9)
Query Neighborhood Hits	269	Target Neighborhood Hits	1644	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TRI47_HUMAN
NC score	0.304518 (rank : 104)	θ value	0.163984 (rank : 173)
Query Neighborhood Hits	269	Target Neighborhood Hits	286	Shared Neighborhood Hits	149
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI10_HUMAN
NC score	0.304511 (rank : 105)	θ value	0.0961366 (rank : 162)
Query Neighborhood Hits	269	Target Neighborhood Hits	315	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRIM6_MOUSE
NC score	0.304430 (rank : 106)	θ value	0.0431538 (rank : 144)
Query Neighborhood Hits	269	Target Neighborhood Hits	451	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

BAZ2B_HUMAN
NC score	0.304041 (rank : 107)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	269	Target Neighborhood Hits	803	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

TRI38_HUMAN
NC score	0.303770 (rank : 108)	θ value	0.00298849 (rank : 91)
Query Neighborhood Hits	269	Target Neighborhood Hits	373	Shared Neighborhood Hits	151
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM6_HUMAN
NC score	0.301751 (rank : 109)	θ value	0.0961366 (rank : 165)
Query Neighborhood Hits	269	Target Neighborhood Hits	412	Shared Neighborhood Hits	161
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TIF1G_HUMAN
NC score	0.300344 (rank : 110)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	269	Target Neighborhood Hits	410	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI60_MOUSE
NC score	0.299455 (rank : 111)	θ value	0.0113563 (rank : 123)
Query Neighborhood Hits	269	Target Neighborhood Hits	240	Shared Neighborhood Hits	143
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI46_MOUSE
NC score	0.299363 (rank : 112)	θ value	0.000602161 (rank : 68)
Query Neighborhood Hits	269	Target Neighborhood Hits	287	Shared Neighborhood Hits	141
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.298712 (rank : 113)	θ value	0.000602161 (rank : 67)
Query Neighborhood Hits	269	Target Neighborhood Hits	291	Shared Neighborhood Hits	142
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM1_HUMAN
NC score	0.298045 (rank : 114)	θ value	0.00390308 (rank : 103)
Query Neighborhood Hits	269	Target Neighborhood Hits	345	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TIF1G_MOUSE
NC score	0.297975 (rank : 115)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	269	Target Neighborhood Hits	498	Shared Neighborhood Hits	156
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI18_MOUSE
NC score	0.297247 (rank : 116)	θ value	0.00390308 (rank : 101)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	152
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRIM1_MOUSE
NC score	0.296325 (rank : 117)	θ value	0.00390308 (rank : 104)
Query Neighborhood Hits	269	Target Neighborhood Hits	361	Shared Neighborhood Hits	154
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI47_MOUSE
NC score	0.296002 (rank : 118)	θ value	0.279714 (rank : 178)
Query Neighborhood Hits	269	Target Neighborhood Hits	295	Shared Neighborhood Hits	149
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM7_HUMAN
NC score	0.295557 (rank : 119)	θ value	0.279714 (rank : 179)
Query Neighborhood Hits	269	Target Neighborhood Hits	336	Shared Neighborhood Hits	155
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI18_HUMAN
NC score	0.295455 (rank : 120)	θ value	0.00390308 (rank : 100)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	152
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI27_MOUSE
NC score	0.295440 (rank : 121)	θ value	0.00035302 (rank : 60)
Query Neighborhood Hits	269	Target Neighborhood Hits	261	Shared Neighborhood Hits	145
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

MYST3_MOUSE
NC score	0.294977 (rank : 122)	θ value	0.000121331 (rank : 47)
Query Neighborhood Hits	269	Target Neighborhood Hits	688	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

TRI27_HUMAN
NC score	0.294185 (rank : 123)	θ value	0.00134147 (rank : 78)
Query Neighborhood Hits	269	Target Neighborhood Hits	273	Shared Neighborhood Hits	152
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI34_MOUSE
NC score	0.293913 (rank : 124)	θ value	0.125558 (rank : 169)
Query Neighborhood Hits	269	Target Neighborhood Hits	332	Shared Neighborhood Hits	138
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRIM7_MOUSE
NC score	0.293322 (rank : 125)	θ value	0.21417 (rank : 175)
Query Neighborhood Hits	269	Target Neighborhood Hits	358	Shared Neighborhood Hits	154
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM3_HUMAN
NC score	0.292985 (rank : 126)	θ value	0.00869519 (rank : 117)
Query Neighborhood Hits	269	Target Neighborhood Hits	357	Shared Neighborhood Hits	155
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

MYST3_HUMAN
NC score	0.292067 (rank : 127)	θ value	0.000121331 (rank : 46)
Query Neighborhood Hits	269	Target Neighborhood Hits	772	Shared Neighborhood Hits	79
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

UBIQ_HUMAN
NC score	0.292065 (rank : 128)	θ value	1.43324e-05 (rank : 32)
Query Neighborhood Hits	269	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	P62988, P02248, P02249, P02250, Q29120, Q6LBL4, Q6LDU5, Q91887, Q91888, Q9BWD6, Q9BX98, Q9UEF2, Q9UEG1, Q9UEK8, Q9UPK7	Gene names	RPS27A, UBA80, UBCEP1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

UBIQ_MOUSE
NC score	0.292065 (rank : 129)	θ value	1.43324e-05 (rank : 33)
Query Neighborhood Hits	269	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	P62991, P02248, P02249, P02250, Q29120, Q62317, Q64223, Q8VCH1, Q91887, Q91888, Q9CXY4, Q9CZM0, Q9D1R5, Q9D8D9, Q9ET23, Q9ET24, Q9Z0H9	Gene names	Rps27a, Uba80, Ubcep1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

BPTF_HUMAN
NC score	0.291253 (rank : 130)	θ value	4.92598e-06 (rank : 24)
Query Neighborhood Hits	269	Target Neighborhood Hits	786	Shared Neighborhood Hits	84
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

TIF1A_HUMAN
NC score	0.290263 (rank : 131)	θ value	1.38821 (rank : 207)
Query Neighborhood Hits	269	Target Neighborhood Hits	327	Shared Neighborhood Hits	138
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI68_MOUSE
NC score	0.289897 (rank : 132)	θ value	0.47712 (rank : 186)
Query Neighborhood Hits	269	Target Neighborhood Hits	356	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

NEDD8_HUMAN
NC score	0.289050 (rank : 133)	θ value	0.00869519 (rank : 110)
Query Neighborhood Hits	269	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q15843, Q6LES6	Gene names	NEDD8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin).

NEDD8_MOUSE
NC score	0.288750 (rank : 134)	θ value	0.00869519 (rank : 111)
Query Neighborhood Hits	269	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	P29595	Gene names	Nedd8, Nedd-8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8).

TRIM2_HUMAN
NC score	0.287459 (rank : 135)	θ value	0.0330416 (rank : 138)
Query Neighborhood Hits	269	Target Neighborhood Hits	330	Shared Neighborhood Hits	162
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.286006 (rank : 136)	θ value	0.0431538 (rank : 142)
Query Neighborhood Hits	269	Target Neighborhood Hits	331	Shared Neighborhood Hits	161
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_MOUSE
NC score	0.285606 (rank : 137)	θ value	0.0431538 (rank : 143)
Query Neighborhood Hits	269	Target Neighborhood Hits	351	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI62_MOUSE
NC score	0.285331 (rank : 138)	θ value	1.06291 (rank : 199)
Query Neighborhood Hits	269	Target Neighborhood Hits	478	Shared Neighborhood Hits	153
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRAF6_MOUSE
NC score	0.283372 (rank : 139)	θ value	0.0148317 (rank : 124)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	144
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TIF1A_MOUSE
NC score	0.282128 (rank : 140)	θ value	1.81305 (rank : 217)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	132
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI62_HUMAN
NC score	0.280187 (rank : 141)	θ value	1.06291 (rank : 198)
Query Neighborhood Hits	269	Target Neighborhood Hits	584	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI41_HUMAN
NC score	0.278561 (rank : 142)	θ value	0.47712 (rank : 184)
Query Neighborhood Hits	269	Target Neighborhood Hits	349	Shared Neighborhood Hits	147
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI68_HUMAN
NC score	0.278004 (rank : 143)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	269	Target Neighborhood Hits	267	Shared Neighborhood Hits	147
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RNF39_HUMAN
NC score	0.277408 (rank : 144)	θ value	0.0113563 (rank : 121)
Query Neighborhood Hits	269	Target Neighborhood Hits	200	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRAF6_HUMAN
NC score	0.274109 (rank : 145)	θ value	0.0252991 (rank : 134)
Query Neighborhood Hits	269	Target Neighborhood Hits	267	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI48_HUMAN
NC score	0.266820 (rank : 146)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	269	Target Neighborhood Hits	192	Shared Neighborhood Hits	138
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

PEX10_HUMAN
NC score	0.266361 (rank : 147)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	143
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

CHFR_HUMAN
NC score	0.266080 (rank : 148)	θ value	0.0431538 (rank : 139)
Query Neighborhood Hits	269	Target Neighborhood Hits	255	Shared Neighborhood Hits	139
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI49_HUMAN
NC score	0.265597 (rank : 149)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

CHFR_MOUSE
NC score	0.263933 (rank : 150)	θ value	0.0431538 (rank : 140)
Query Neighborhood Hits	269	Target Neighborhood Hits	264	Shared Neighborhood Hits	139
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHD5_HUMAN
NC score	0.263803 (rank : 151)	θ value	1.17247e-07 (rank : 14)
Query Neighborhood Hits	269	Target Neighborhood Hits	349	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

TRI36_MOUSE
NC score	0.262693 (rank : 152)	θ value	0.0193708 (rank : 131)
Query Neighborhood Hits	269	Target Neighborhood Hits	266	Shared Neighborhood Hits	123
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
NC score	0.261169 (rank : 153)	θ value	0.0431538 (rank : 141)
Query Neighborhood Hits	269	Target Neighborhood Hits	282	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

CHD4_MOUSE
NC score	0.258441 (rank : 154)	θ value	1.06045e-08 (rank : 7)
Query Neighborhood Hits	269	Target Neighborhood Hits	408	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.256104 (rank : 155)	θ value	1.53129e-07 (rank : 15)
Query Neighborhood Hits	269	Target Neighborhood Hits	365	Shared Neighborhood Hits	86
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

TRI66_MOUSE
NC score	0.255843 (rank : 156)	θ value	1.06291 (rank : 200)
Query Neighborhood Hits	269	Target Neighborhood Hits	491	Shared Neighborhood Hits	110
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI15_HUMAN
NC score	0.254450 (rank : 157)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	269	Target Neighborhood Hits	395	Shared Neighborhood Hits	143
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

CHD3_HUMAN
NC score	0.253544 (rank : 158)	θ value	5.81887e-07 (rank : 18)
Query Neighborhood Hits	269	Target Neighborhood Hits	397	Shared Neighborhood Hits	86
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

TRI66_HUMAN
NC score	0.250513 (rank : 159)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	269	Target Neighborhood Hits	479	Shared Neighborhood Hits	113
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ZN179_HUMAN
NC score	0.250283 (rank : 160)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	269	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI32_HUMAN
NC score	0.243643 (rank : 161)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	269	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.242172 (rank : 162)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	269	Target Neighborhood Hits	271	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

R113B_HUMAN
NC score	0.241794 (rank : 163)	θ value	0.365318 (rank : 182)
Query Neighborhood Hits	269	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRIM9_HUMAN
NC score	0.240367 (rank : 164)	θ value	2.36792 (rank : 229)
Query Neighborhood Hits	269	Target Neighborhood Hits	294	Shared Neighborhood Hits	133
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

HRX_HUMAN
NC score	0.237697 (rank : 165)	θ value	9.29e-05 (rank : 44)
Query Neighborhood Hits	269	Target Neighborhood Hits	825	Shared Neighborhood Hits	75
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TRIM9_MOUSE
NC score	0.237255 (rank : 166)	θ value	2.36792 (rank : 230)
Query Neighborhood Hits	269	Target Neighborhood Hits	274	Shared Neighborhood Hits	132
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RNF4_HUMAN
NC score	0.230995 (rank : 167)	θ value	1.81305 (rank : 214)
Query Neighborhood Hits	269	Target Neighborhood Hits	212	Shared Neighborhood Hits	123
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRAF5_MOUSE
NC score	0.230919 (rank : 168)	θ value	0.0193708 (rank : 129)
Query Neighborhood Hits	269	Target Neighborhood Hits	355	Shared Neighborhood Hits	114
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

UBL4A_HUMAN
NC score	0.229625 (rank : 169)	θ value	0.00228821 (rank : 89)
Query Neighborhood Hits	269	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	P11441	Gene names	UBL4A, DXS254E, GDX, UBL4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

RNF4_MOUSE
NC score	0.229365 (rank : 170)	θ value	1.81305 (rank : 215)
Query Neighborhood Hits	269	Target Neighborhood Hits	212	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

MTF2_HUMAN
NC score	0.227353 (rank : 171)	θ value	0.00390308 (rank : 93)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MLL4_HUMAN
NC score	0.227225 (rank : 172)	θ value	0.00134147 (rank : 76)
Query Neighborhood Hits	269	Target Neighborhood Hits	722	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ZMY11_MOUSE
NC score	0.226214 (rank : 173)	θ value	0.00869519 (rank : 118)
Query Neighborhood Hits	269	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

MTF2_MOUSE
NC score	0.225767 (rank : 174)	θ value	0.00390308 (rank : 94)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

RN169_HUMAN
NC score	0.225609 (rank : 175)	θ value	0.47712 (rank : 183)
Query Neighborhood Hits	269	Target Neighborhood Hits	203	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SMRA3_HUMAN
NC score	0.225242 (rank : 176)	θ value	0.0736092 (rank : 153)
Query Neighborhood Hits	269	Target Neighborhood Hits	265	Shared Neighborhood Hits	150
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
NC score	0.224778 (rank : 177)	θ value	0.0193708 (rank : 128)
Query Neighborhood Hits	269	Target Neighborhood Hits	267	Shared Neighborhood Hits	149
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

PKCB1_HUMAN
NC score	0.220065 (rank : 178)	θ value	0.279714 (rank : 177)
Query Neighborhood Hits	269	Target Neighborhood Hits	488	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRAF4_HUMAN
NC score	0.216238 (rank : 179)	θ value	0.0330416 (rank : 137)
Query Neighborhood Hits	269	Target Neighborhood Hits	373	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRI37_HUMAN
NC score	0.214010 (rank : 180)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	269	Target Neighborhood Hits	307	Shared Neighborhood Hits	131
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.213558 (rank : 181)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	269	Target Neighborhood Hits	316	Shared Neighborhood Hits	130
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

R113A_HUMAN
NC score	0.212834 (rank : 182)	θ value	1.06291 (rank : 196)
Query Neighborhood Hits	269	Target Neighborhood Hits	177	Shared Neighborhood Hits	118
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRAF3_MOUSE
NC score	0.212394 (rank : 183)	θ value	0.00228821 (rank : 84)
Query Neighborhood Hits	269	Target Neighborhood Hits	476	Shared Neighborhood Hits	116
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RNF41_HUMAN
NC score	0.211850 (rank : 184)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	269	Target Neighborhood Hits	226	Shared Neighborhood Hits	135
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.211551 (rank : 185)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	269	Target Neighborhood Hits	224	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

PCGF6_MOUSE
NC score	0.211540 (rank : 186)	θ value	0.62314 (rank : 191)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	108
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRAF2_HUMAN
NC score	0.211030 (rank : 187)	θ value	0.00390308 (rank : 99)
Query Neighborhood Hits	269	Target Neighborhood Hits	402	Shared Neighborhood Hits	115
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

ZMY11_HUMAN
NC score	0.210928 (rank : 188)	θ value	0.0563607 (rank : 148)
Query Neighborhood Hits	269	Target Neighborhood Hits	201	Shared Neighborhood Hits	57
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PCGF6_HUMAN
NC score	0.209542 (rank : 189)	θ value	0.62314 (rank : 190)
Query Neighborhood Hits	269	Target Neighborhood Hits	178	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RNF5_HUMAN
NC score	0.207108 (rank : 190)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	269	Target Neighborhood Hits	206	Shared Neighborhood Hits	121
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.205539 (rank : 191)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	269	Target Neighborhood Hits	206	Shared Neighborhood Hits	119
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRAF3_HUMAN
NC score	0.205347 (rank : 192)	θ value	0.00298849 (rank : 90)
Query Neighborhood Hits	269	Target Neighborhood Hits	463	Shared Neighborhood Hits	112
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF2_MOUSE
NC score	0.204530 (rank : 193)	θ value	0.0330416 (rank : 136)
Query Neighborhood Hits	269	Target Neighborhood Hits	394	Shared Neighborhood Hits	112
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF5_HUMAN
NC score	0.204393 (rank : 194)	θ value	0.125558 (rank : 167)
Query Neighborhood Hits	269	Target Neighborhood Hits	396	Shared Neighborhood Hits	113
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

NSD1_MOUSE
NC score	0.203290 (rank : 195)	θ value	0.0961366 (rank : 157)
Query Neighborhood Hits	269	Target Neighborhood Hits	472	Shared Neighborhood Hits	75
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MEFV_HUMAN
NC score	0.202040 (rank : 196)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	269	Target Neighborhood Hits	431	Shared Neighborhood Hits	87
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI14_MOUSE
NC score	0.201780 (rank : 197)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	269	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

NSD1_HUMAN
NC score	0.201014 (rank : 198)	θ value	0.0961366 (rank : 156)
Query Neighborhood Hits	269	Target Neighborhood Hits	427	Shared Neighborhood Hits	75
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TRI14_HUMAN
NC score	0.200493 (rank : 199)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	269	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

MEFV_MOUSE
NC score	0.196540 (rank : 200)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	269	Target Neighborhood Hits	236	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

BRPF1_HUMAN
NC score	0.195445 (rank : 201)	θ value	0.163984 (rank : 170)
Query Neighborhood Hits	269	Target Neighborhood Hits	259	Shared Neighborhood Hits	70
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

DTX3_MOUSE
NC score	0.193904 (rank : 202)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	269	Target Neighborhood Hits	202	Shared Neighborhood Hits	124
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TAF3_HUMAN
NC score	0.192911 (rank : 203)	θ value	0.0961366 (rank : 161)
Query Neighborhood Hits	269	Target Neighborhood Hits	568	Shared Neighborhood Hits	65
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI16_MOUSE
NC score	0.192789 (rank : 204)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	269	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

RFWD2_HUMAN
NC score	0.192363 (rank : 205)	θ value	0.0961366 (rank : 158)
Query Neighborhood Hits	269	Target Neighborhood Hits	518	Shared Neighborhood Hits	156
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN185_HUMAN
NC score	0.191830 (rank : 206)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	269	Target Neighborhood Hits	213	Shared Neighborhood Hits	123
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RFWD2_MOUSE
NC score	0.191707 (rank : 207)	θ value	0.0961366 (rank : 159)
Query Neighborhood Hits	269	Target Neighborhood Hits	535	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

UBL4A_MOUSE
NC score	0.191608 (rank : 208)	θ value	0.0431538 (rank : 147)
Query Neighborhood Hits	269	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	P21126	Gene names	Ubl4a, Gdx, Ubl4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

BRD1_HUMAN
NC score	0.191337 (rank : 209)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	269	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

RN185_MOUSE
NC score	0.190769 (rank : 210)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	269	Target Neighborhood Hits	211	Shared Neighborhood Hits	123
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

DTX3_HUMAN
NC score	0.188650 (rank : 211)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	269	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

PCGF4_MOUSE
NC score	0.188453 (rank : 212)	θ value	0.365318 (rank : 181)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.188380 (rank : 213)	θ value	0.365318 (rank : 180)
Query Neighborhood Hits	269	Target Neighborhood Hits	161	Shared Neighborhood Hits	104
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

RFPL3_HUMAN
NC score	0.185939 (rank : 214)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	269	Target Neighborhood Hits	134	Shared Neighborhood Hits	90
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

PCGF2_HUMAN
NC score	0.184663 (rank : 215)	θ value	0.62314 (rank : 188)
Query Neighborhood Hits	269	Target Neighborhood Hits	222	Shared Neighborhood Hits	102
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.184581 (rank : 216)	θ value	0.62314 (rank : 189)
Query Neighborhood Hits	269	Target Neighborhood Hits	213	Shared Neighborhood Hits	101
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TAF3_MOUSE
NC score	0.183940 (rank : 217)	θ value	0.125558 (rank : 166)
Query Neighborhood Hits	269	Target Neighborhood Hits	463	Shared Neighborhood Hits	59
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI16_HUMAN
NC score	0.181509 (rank : 218)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	269	Target Neighborhood Hits	231	Shared Neighborhood Hits	73
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
NC score	0.181371 (rank : 219)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	269	Target Neighborhood Hits	273	Shared Neighborhood Hits	77
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
NC score	0.181200 (rank : 220)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	269	Target Neighborhood Hits	306	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

BSPRY_MOUSE
NC score	0.180766 (rank : 221)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BRPF3_HUMAN
NC score	0.180414 (rank : 222)	θ value	0.163984 (rank : 171)
Query Neighborhood Hits	269	Target Neighborhood Hits	217	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

RFPL2_HUMAN
NC score	0.179053 (rank : 223)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL1_HUMAN
NC score	0.178689 (rank : 224)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI44_MOUSE
NC score	0.176677 (rank : 225)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	269	Target Neighborhood Hits	327	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

JADE3_HUMAN
NC score	0.176500 (rank : 226)	θ value	0.21417 (rank : 174)
Query Neighborhood Hits	269	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

RAD18_HUMAN
NC score	0.174964 (rank : 227)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	269	Target Neighborhood Hits	284	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TRI44_HUMAN
NC score	0.174592 (rank : 228)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	269	Target Neighborhood Hits	393	Shared Neighborhood Hits	74
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

BSPRY_HUMAN
NC score	0.174362 (rank : 229)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	269	Target Neighborhood Hits	115	Shared Neighborhood Hits	63
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RAD18_MOUSE
NC score	0.173054 (rank : 230)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	269	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

JADE3_MOUSE
NC score	0.171959 (rank : 231)	θ value	0.279714 (rank : 176)
Query Neighborhood Hits	269	Target Neighborhood Hits	174	Shared Neighborhood Hits	68
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

TRI42_MOUSE
NC score	0.171125 (rank : 232)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	269	Target Neighborhood Hits	316	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ERMAP_HUMAN
NC score	0.170740 (rank : 233)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	269	Target Neighborhood Hits	155	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI42_HUMAN
NC score	0.166472 (rank : 234)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	269	Target Neighborhood Hits	283	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

JADE1_HUMAN
NC score	0.166006 (rank : 235)	θ value	1.38821 (rank : 203)
Query Neighborhood Hits	269	Target Neighborhood Hits	140	Shared Neighborhood Hits	66
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.165510 (rank : 236)	θ value	1.38821 (rank : 204)
Query Neighborhood Hits	269	Target Neighborhood Hits	160	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

PML_MOUSE
NC score	0.165304 (rank : 237)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	269	Target Neighborhood Hits	246	Shared Neighborhood Hits	104
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

LNX2_HUMAN
NC score	0.163998 (rank : 238)	θ value	0.0736092 (rank : 151)
Query Neighborhood Hits	269	Target Neighborhood Hits	389	Shared Neighborhood Hits	145
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.161231 (rank : 239)	θ value	0.0961366 (rank : 155)
Query Neighborhood Hits	269	Target Neighborhood Hits	407	Shared Neighborhood Hits	146
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TRI45_HUMAN
NC score	0.158871 (rank : 240)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	269	Target Neighborhood Hits	155	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

JADE2_HUMAN
NC score	0.157458 (rank : 241)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

RN146_HUMAN
NC score	0.157417 (rank : 242)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	269	Target Neighborhood Hits	162	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

ERMAP_MOUSE
NC score	0.157326 (rank : 243)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	269	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

LY10_HUMAN
NC score	0.157311 (rank : 244)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	269	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

PZRN3_MOUSE
NC score	0.156866 (rank : 245)	θ value	0.813845 (rank : 195)
Query Neighborhood Hits	269	Target Neighborhood Hits	447	Shared Neighborhood Hits	148
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RN146_MOUSE
NC score	0.156402 (rank : 246)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	269	Target Neighborhood Hits	161	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

PZRN3_HUMAN
NC score	0.155690 (rank : 247)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	269	Target Neighborhood Hits	461	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRI45_MOUSE
NC score	0.154767 (rank : 248)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	269	Target Neighborhood Hits	155	Shared Neighborhood Hits	85
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRAF4_MOUSE
NC score	0.154117 (rank : 249)	θ value	1.81305 (rank : 218)
Query Neighborhood Hits	269	Target Neighborhood Hits	338	Shared Neighborhood Hits	94
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

LNX1_HUMAN
NC score	0.153681 (rank : 250)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	269	Target Neighborhood Hits	379	Shared Neighborhood Hits	146
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PML_HUMAN
NC score	0.153254 (rank : 251)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	269	Target Neighborhood Hits	248	Shared Neighborhood Hits	100
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

BT1A1_MOUSE
NC score	0.153036 (rank : 252)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	269	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

SPRY4_MOUSE
NC score	0.152860 (rank : 253)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	269	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BT1A1_HUMAN
NC score	0.151370 (rank : 254)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	269	Target Neighborhood Hits	322	Shared Neighborhood Hits	56
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
NC score	0.151258 (rank : 255)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	269	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL9_HUMAN
NC score	0.149733 (rank : 256)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	269	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT3A1_HUMAN
NC score	0.149609 (rank : 257)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	269	Target Neighborhood Hits	229	Shared Neighborhood Hits	56
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT2A2_HUMAN
NC score	0.149468 (rank : 258)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	269	Target Neighborhood Hits	191	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

RN183_HUMAN
NC score	0.149276 (rank : 259)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

JADE2_MOUSE
NC score	0.147907 (rank : 260)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	269	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

SPRY4_HUMAN
NC score	0.147000 (rank : 261)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	269	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BTNL3_HUMAN
NC score	0.146530 (rank : 262)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	269	Target Neighborhood Hits	143	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT2A3_HUMAN
NC score	0.144462 (rank : 263)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	269	Target Neighborhood Hits	195	Shared Neighborhood Hits	52
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RN141_MOUSE
NC score	0.143824 (rank : 264)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	269	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.143598 (rank : 265)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	269	Target Neighborhood Hits	199	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

LNX1_MOUSE
NC score	0.143373 (rank : 266)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	269	Target Neighborhood Hits	377	Shared Neighborhood Hits	139
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

BT2A1_HUMAN
NC score	0.143298 (rank : 267)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	269	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BTNL8_HUMAN
NC score	0.140809 (rank : 268)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	269	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

DTX3L_HUMAN
NC score	0.136725 (rank : 269)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	269	Target Neighborhood Hits	187	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

PZRN4_HUMAN
NC score	0.132001 (rank : 270)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	269	Target Neighborhood Hits	438	Shared Neighborhood Hits	142
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

BAT3_HUMAN
NC score	0.131524 (rank : 271)	θ value	0.00390308 (rank : 92)
Query Neighborhood Hits	269	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
NC score	0.129788 (rank : 272)	θ value	0.0252991 (rank : 132)
Query Neighborhood Hits	269	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

RN183_MOUSE
NC score	0.129077 (rank : 273)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	89
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

BIRC7_HUMAN
NC score	0.128715 (rank : 274)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	269	Target Neighborhood Hits	185	Shared Neighborhood Hits	120
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BRE1B_MOUSE
NC score	0.128294 (rank : 275)	θ value	0.000786445 (rank : 71)
Query Neighborhood Hits	269	Target Neighborhood Hits	970	Shared Neighborhood Hits	123
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

RKHD1_HUMAN
NC score	0.127282 (rank : 276)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	269	Target Neighborhood Hits	163	Shared Neighborhood Hits	58
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

PEX2_MOUSE
NC score	0.125765 (rank : 277)	θ value	1.38821 (rank : 205)
Query Neighborhood Hits	269	Target Neighborhood Hits	57	Shared Neighborhood Hits	49
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

BRE1B_HUMAN
NC score	0.125755 (rank : 278)	θ value	0.000786445 (rank : 70)
Query Neighborhood Hits	269	Target Neighborhood Hits	1040	Shared Neighborhood Hits	131
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TOPRS_MOUSE
NC score	0.125548 (rank : 279)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	269	Target Neighborhood Hits	263	Shared Neighborhood Hits	98
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.122979 (rank : 280)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	269	Target Neighborhood Hits	286	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

SP110_HUMAN
NC score	0.121878 (rank : 281)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	269	Target Neighborhood Hits	141	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

RNF34_HUMAN
NC score	0.119519 (rank : 282)	θ value	0.0961366 (rank : 160)
Query Neighborhood Hits	269	Target Neighborhood Hits	153	Shared Neighborhood Hits	66
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

CM007_MOUSE
NC score	0.118833 (rank : 283)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	269	Target Neighborhood Hits	416	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RNF34_MOUSE
NC score	0.118487 (rank : 284)	θ value	0.163984 (rank : 172)
Query Neighborhood Hits	269	Target Neighborhood Hits	160	Shared Neighborhood Hits	66
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRAF7_MOUSE
NC score	0.115643 (rank : 285)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	269	Target Neighborhood Hits	470	Shared Neighborhood Hits	138
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.114633 (rank : 286)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	269	Target Neighborhood Hits	482	Shared Neighborhood Hits	141
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

RBBP6_MOUSE
NC score	0.113392 (rank : 287)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	269	Target Neighborhood Hits	1014	Shared Neighborhood Hits	133
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PEX2_HUMAN
NC score	0.108464 (rank : 288)	θ value	1.81305 (rank : 212)
Query Neighborhood Hits	269	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PHF1_HUMAN
NC score	0.107927 (rank : 289)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	269	Target Neighborhood Hits	117	Shared Neighborhood Hits	54
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

RBBP6_HUMAN
NC score	0.107529 (rank : 290)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	269	Target Neighborhood Hits	1135	Shared Neighborhood Hits	141
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PHF1_MOUSE
NC score	0.107476 (rank : 291)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	269	Target Neighborhood Hits	116	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

DPF3_MOUSE
NC score	0.106786 (rank : 292)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	269	Target Neighborhood Hits	327	Shared Neighborhood Hits	12
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

TCF19_HUMAN
NC score	0.106011 (rank : 293)	θ value	1.81305 (rank : 216)
Query Neighborhood Hits	269	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

BRE1A_HUMAN
NC score	0.105402 (rank : 294)	θ value	0.00509761 (rank : 105)
Query Neighborhood Hits	269	Target Neighborhood Hits	1071	Shared Neighborhood Hits	117
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CM007_HUMAN
NC score	0.104575 (rank : 295)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	269	Target Neighborhood Hits	422	Shared Neighborhood Hits	98
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

BRE1A_MOUSE
NC score	0.103445 (rank : 296)	θ value	0.00509761 (rank : 106)
Query Neighborhood Hits	269	Target Neighborhood Hits	1025	Shared Neighborhood Hits	111
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CXCC1_HUMAN
NC score	0.100482 (rank : 297)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	269	Target Neighborhood Hits	143	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

AF17_HUMAN
NC score	0.097982 (rank : 298)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	269	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

RNF37_MOUSE
NC score	0.096419 (rank : 299)	θ value	0.62314 (rank : 192)
Query Neighborhood Hits	269	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

AMFR2_HUMAN
NC score	0.096413 (rank : 300)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	269	Target Neighborhood Hits	219	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

JHD3A_MOUSE
NC score	0.094563 (rank : 301)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	269	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

CXCC1_MOUSE
NC score	0.093642 (rank : 302)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	269	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

JHD3C_MOUSE
NC score	0.092548 (rank : 303)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	269	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_HUMAN
NC score	0.092372 (rank : 304)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	269	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

RC3H1_MOUSE
NC score	0.091604 (rank : 305)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	269	Target Neighborhood Hits	244	Shared Neighborhood Hits	105
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

AF10_HUMAN
NC score	0.091595 (rank : 306)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	269	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
NC score	0.091462 (rank : 307)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	269	Target Neighborhood Hits	182	Shared Neighborhood Hits	45
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

DPF3_HUMAN
NC score	0.090760 (rank : 308)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	269	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

AMFR_MOUSE
NC score	0.090598 (rank : 309)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	269	Target Neighborhood Hits	208	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

JHD3B_MOUSE
NC score	0.090250 (rank : 310)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	269	Target Neighborhood Hits	152	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_HUMAN
NC score	0.090034 (rank : 311)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	269	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3B_HUMAN
NC score	0.089238 (rank : 312)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	269	Target Neighborhood Hits	128	Shared Neighborhood Hits	30
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

FSD1L_MOUSE
NC score	0.087418 (rank : 313)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	269	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

RC3H1_HUMAN
NC score	0.086094 (rank : 314)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	269	Target Neighborhood Hits	433	Shared Neighborhood Hits	111
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

MYLIP_HUMAN
NC score	0.085838 (rank : 315)	θ value	0.0736092 (rank : 152)
Query Neighborhood Hits	269	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CBL_MOUSE
NC score	0.084989 (rank : 316)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	269	Target Neighborhood Hits	426	Shared Neighborhood Hits	129
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RNF13_HUMAN
NC score	0.084536 (rank : 317)	θ value	1.06291 (rank : 197)
Query Neighborhood Hits	269	Target Neighborhood Hits	147	Shared Neighborhood Hits	60
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

NHLC1_MOUSE
NC score	0.083256 (rank : 318)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	269	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RNF13_MOUSE
NC score	0.082947 (rank : 319)	θ value	1.38821 (rank : 206)
Query Neighborhood Hits	269	Target Neighborhood Hits	164	Shared Neighborhood Hits	66
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

CBLC_MOUSE
NC score	0.082722 (rank : 320)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	269	Target Neighborhood Hits	186	Shared Neighborhood Hits	102
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBLC_HUMAN
NC score	0.082339 (rank : 321)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	269	Target Neighborhood Hits	173	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

MNAB_MOUSE
NC score	0.081626 (rank : 322)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	269	Target Neighborhood Hits	231	Shared Neighborhood Hits	90
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RN152_MOUSE
NC score	0.081518 (rank : 323)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	269	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

MYLIP_MOUSE
NC score	0.081299 (rank : 324)	θ value	0.0330416 (rank : 135)
Query Neighborhood Hits	269	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CBL_HUMAN
NC score	0.081271 (rank : 325)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	269	Target Neighborhood Hits	353	Shared Neighborhood Hits	124
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

RNF26_HUMAN
NC score	0.080925 (rank : 326)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	269	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

MNAB_HUMAN
NC score	0.080563 (rank : 327)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	269	Target Neighborhood Hits	196	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

FSD1L_HUMAN
NC score	0.080449 (rank : 328)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	269	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

CBLB_MOUSE
NC score	0.080053 (rank : 329)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	269	Target Neighborhood Hits	277	Shared Neighborhood Hits	116
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

TRAF1_MOUSE
NC score	0.079759 (rank : 330)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	269	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

CBLB_HUMAN
NC score	0.079281 (rank : 331)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	269	Target Neighborhood Hits	261	Shared Neighborhood Hits	116
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

TRAF1_HUMAN
NC score	0.079035 (rank : 332)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

CECR2_HUMAN
NC score	0.077158 (rank : 333)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	269	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

UBD_MOUSE
NC score	0.077124 (rank : 334)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	269	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P63072, Q9WV10	Gene names	Ubd, Fat10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

RN152_HUMAN
NC score	0.077123 (rank : 335)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	269	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

PHF22_MOUSE
NC score	0.076956 (rank : 336)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	269	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SMCA2_HUMAN
NC score	0.074053 (rank : 337)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	269	Target Neighborhood Hits	503	Shared Neighborhood Hits	31
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

NHLC1_HUMAN
NC score	0.073707 (rank : 338)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	269	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PHF11_HUMAN
NC score	0.072631 (rank : 339)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	269	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

SMCA4_HUMAN
NC score	0.072624 (rank : 340)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	269	Target Neighborhood Hits	597	Shared Neighborhood Hits	31
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

PHF22_HUMAN
NC score	0.071646 (rank : 341)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	269	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SET1A_HUMAN
NC score	0.070868 (rank : 342)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	269	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ARD1_MOUSE
NC score	0.070126 (rank : 343)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	269	Target Neighborhood Hits	573	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

JARD2_HUMAN
NC score	0.069750 (rank : 344)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	269	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

RN167_MOUSE
NC score	0.069426 (rank : 345)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	269	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

JARD2_MOUSE
NC score	0.067138 (rank : 346)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	269	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PCAF_HUMAN
NC score	0.067112 (rank : 347)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	269	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

RN167_HUMAN
NC score	0.067074 (rank : 348)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	269	Target Neighborhood Hits	157	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

ARD1_HUMAN
NC score	0.066900 (rank : 349)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	269	Target Neighborhood Hits	621	Shared Neighborhood Hits	71
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

BRD8_HUMAN
NC score	0.066554 (rank : 350)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	269	Target Neighborhood Hits	292	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

TRAIP_HUMAN
NC score	0.065816 (rank : 351)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	269	Target Neighborhood Hits	780	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

BIRC8_HUMAN
NC score	0.064097 (rank : 352)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	269	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

GCNL2_MOUSE
NC score	0.063697 (rank : 353)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	269	Target Neighborhood Hits	146	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

GCNL2_HUMAN
NC score	0.063153 (rank : 354)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	269	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

BRD8_MOUSE
NC score	0.063040 (rank : 355)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	269	Target Neighborhood Hits	422	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

MYST2_HUMAN
NC score	0.060802 (rank : 356)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	269	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
NC score	0.060461 (rank : 357)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	269	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

RFFL_HUMAN
NC score	0.060170 (rank : 358)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	269	Target Neighborhood Hits	175	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MYST1_HUMAN
NC score	0.059986 (rank : 359)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	269	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

TIP60_HUMAN
NC score	0.059982 (rank : 360)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	269	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
NC score	0.059971 (rank : 361)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	269	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

CHD6_HUMAN
NC score	0.059962 (rank : 362)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	269	Target Neighborhood Hits	342	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

MYST1_MOUSE
NC score	0.059932 (rank : 363)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	269	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

UB7I3_MOUSE
NC score	0.059736 (rank : 364)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	269	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

CHD2_HUMAN
NC score	0.059705 (rank : 365)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	269	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

PHF20_HUMAN
NC score	0.059340 (rank : 366)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	269	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

MGRN1_HUMAN
NC score	0.059258 (rank : 367)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	269	Target Neighborhood Hits	192	Shared Neighborhood Hits	76
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

SETD2_HUMAN
NC score	0.059181 (rank : 368)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	269	Target Neighborhood Hits	412	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

BRD2_HUMAN
NC score	0.058996 (rank : 369)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	269	Target Neighborhood Hits	242	Shared Neighborhood Hits	27
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

ATRX_MOUSE
NC score	0.058961 (rank : 370)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	269	Target Neighborhood Hits	682	Shared Neighborhood Hits	40
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

RFFL_MOUSE
NC score	0.058959 (rank : 371)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	269	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TAF1_HUMAN
NC score	0.058558 (rank : 372)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	269	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

BARD1_HUMAN
NC score	0.058388 (rank : 373)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	269	Target Neighborhood Hits	427	Shared Neighborhood Hits	92
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

PHF20_MOUSE
NC score	0.058146 (rank : 374)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	269	Target Neighborhood Hits	513	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

ING5_HUMAN
NC score	0.058007 (rank : 375)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING1_MOUSE
NC score	0.057871 (rank : 376)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	269	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

CHD9_MOUSE
NC score	0.057609 (rank : 377)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	269	Target Neighborhood Hits	427	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

MGRN1_MOUSE
NC score	0.057596 (rank : 378)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	269	Target Neighborhood Hits	149	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

CHD1_MOUSE
NC score	0.057537 (rank : 379)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	269	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD9_HUMAN
NC score	0.057443 (rank : 380)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	269	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD1_HUMAN
NC score	0.057395 (rank : 381)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	269	Target Neighborhood Hits	337	Shared Neighborhood Hits	15
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

BARD1_MOUSE
NC score	0.057363 (rank : 382)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	269	Target Neighborhood Hits	411	Shared Neighborhood Hits	89
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BRD4_HUMAN
NC score	0.057347 (rank : 383)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	269	Target Neighborhood Hits	851	Shared Neighborhood Hits	35
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CHD8_HUMAN
NC score	0.057313 (rank : 384)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	269	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

PHF7_HUMAN
NC score	0.056926 (rank : 385)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	269	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

TRAIP_MOUSE
NC score	0.056916 (rank : 386)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	269	Target Neighborhood Hits	745	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

JHD3D_MOUSE
NC score	0.056915 (rank : 387)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	269	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

TAF1L_HUMAN
NC score	0.056770 (rank : 388)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	269	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

SETD8_HUMAN
NC score	0.056562 (rank : 389)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	269	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

BRD9_HUMAN
NC score	0.056409 (rank : 390)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	269	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
NC score	0.056396 (rank : 391)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	269	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD4_MOUSE
NC score	0.056264 (rank : 392)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	269	Target Neighborhood Hits	845	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

JHD3D_HUMAN
NC score	0.056157 (rank : 393)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	269	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

ING5_MOUSE
NC score	0.055904 (rank : 394)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	269	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

SETD8_MOUSE
NC score	0.055871 (rank : 395)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	269	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

BIRC3_MOUSE
NC score	0.055132 (rank : 396)	θ value	1.38821 (rank : 201)
Query Neighborhood Hits	269	Target Neighborhood Hits	113	Shared Neighborhood Hits	56
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

RNF32_HUMAN
NC score	0.055096 (rank : 397)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	269	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

SMCA1_HUMAN
NC score	0.054744 (rank : 398)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	269	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

MAT1_HUMAN
NC score	0.054727 (rank : 399)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	269	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

ATRX_HUMAN
NC score	0.054532 (rank : 400)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	269	Target Neighborhood Hits	842	Shared Neighborhood Hits	46
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

SMCA1_MOUSE
NC score	0.054462 (rank : 401)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	269	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

ERCC6_HUMAN
NC score	0.054366 (rank : 402)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	269	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

UCRP_MOUSE
NC score	0.054157 (rank : 403)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	269	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q64339, Q8K0H3	Gene names	Isg15, G1p2, Ucrp
Domain Architecture
Description	Ubiquitin cross-reactive protein precursor (Interferon-stimulated protein 15) (IP17).

PHF6_HUMAN
NC score	0.054147 (rank : 404)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	269	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

SMCA5_MOUSE
NC score	0.053839 (rank : 405)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	269	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.053752 (rank : 406)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	269	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

PHF7_MOUSE
NC score	0.053520 (rank : 407)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

SMRCD_MOUSE
NC score	0.053518 (rank : 408)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	269	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

MAT1_MOUSE
NC score	0.053308 (rank : 409)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	269	Target Neighborhood Hits	217	Shared Neighborhood Hits	40
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

SMRCD_HUMAN
NC score	0.052881 (rank : 410)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	269	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

BRD3_HUMAN
NC score	0.052532 (rank : 411)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	269	Target Neighborhood Hits	369	Shared Neighborhood Hits	19
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

PHF6_MOUSE
NC score	0.052262 (rank : 412)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	269	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

RN123_HUMAN
NC score	0.051958 (rank : 413)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	269	Target Neighborhood Hits	175	Shared Neighborhood Hits	88
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
NC score	0.051863 (rank : 414)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	269	Target Neighborhood Hits	174	Shared Neighborhood Hits	89
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BRD3_MOUSE
NC score	0.051802 (rank : 415)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	269	Target Neighborhood Hits	402	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

MKRN3_HUMAN
NC score	0.051649 (rank : 416)	θ value	1.81305 (rank : 211)
Query Neighborhood Hits	269	Target Neighborhood Hits	165	Shared Neighborhood Hits	53
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

PHF2_HUMAN
NC score	0.051139 (rank : 417)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	269	Target Neighborhood Hits	208	Shared Neighborhood Hits	31
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ING3_HUMAN
NC score	0.050972 (rank : 418)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	269	Target Neighborhood Hits	178	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

UB7I3_HUMAN
NC score	0.050891 (rank : 419)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	269	Target Neighborhood Hits	136	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RAD54_HUMAN
NC score	0.050576 (rank : 420)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	269	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

BRD7_HUMAN
NC score	0.050488 (rank : 421)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	269	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

EP300_HUMAN
NC score	0.050486 (rank : 422)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	269	Target Neighborhood Hits	821	Shared Neighborhood Hits	38
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PHF2_MOUSE
NC score	0.050481 (rank : 423)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	269	Target Neighborhood Hits	241	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

RNF32_MOUSE
NC score	0.050440 (rank : 424)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	269	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

ING1_HUMAN
NC score	0.050319 (rank : 425)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

BRD7_MOUSE
NC score	0.050281 (rank : 426)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	269	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

PJA1_HUMAN
NC score	0.050190 (rank : 427)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	269	Target Neighborhood Hits	159	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

EZH1_HUMAN
NC score	0.050180 (rank : 428)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	269	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

BRDT_HUMAN
NC score	0.050134 (rank : 429)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	269	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

EZH1_MOUSE
NC score	0.050112 (rank : 430)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	269	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

SMAL1_MOUSE
NC score	0.050053 (rank : 431)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	269	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

RA54B_HUMAN
NC score	0.050051 (rank : 432)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	269	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RN133_HUMAN
NC score	0.046750 (rank : 433)	θ value	1.81305 (rank : 213)
Query Neighborhood Hits	269	Target Neighborhood Hits	108	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RD23B_HUMAN
NC score	0.046534 (rank : 434)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	269	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

JHD1A_HUMAN
NC score	0.042940 (rank : 435)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	269	Target Neighborhood Hits	133	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

DCTN4_MOUSE
NC score	0.039219 (rank : 436)	θ value	1.38821 (rank : 202)
Query Neighborhood Hits	269	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

LRSM1_HUMAN
NC score	0.038698 (rank : 437)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	269	Target Neighborhood Hits	1078	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

DCTN4_HUMAN
NC score	0.035997 (rank : 438)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	269	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

PRKN2_HUMAN
NC score	0.033686 (rank : 439)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	269	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PCLO_MOUSE
NC score	0.031567 (rank : 440)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	269	Target Neighborhood Hits	2275	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZN638_MOUSE
NC score	0.028853 (rank : 441)	θ value	0.62314 (rank : 193)
Query Neighborhood Hits	269	Target Neighborhood Hits	318	Shared Neighborhood Hits	13
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

SRRM2_HUMAN
NC score	0.019492 (rank : 442)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	269	Target Neighborhood Hits	1296	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

FHL2_HUMAN
NC score	0.012705 (rank : 443)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	269	Target Neighborhood Hits	533	Shared Neighborhood Hits	16
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

LTB1L_MOUSE
NC score	0.011721 (rank : 444)	θ value	1.81305 (rank : 209)
Query Neighborhood Hits	269	Target Neighborhood Hits	514	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.011228 (rank : 445)	θ value	1.81305 (rank : 210)
Query Neighborhood Hits	269	Target Neighborhood Hits	479	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CDCA5_MOUSE
NC score	0.011003 (rank : 446)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	269	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPY3, Q78HI6	Gene names	Cdca5
Domain Architecture	No domain graphic available
Description	Sororin (Cell division cycle-associated protein 5).

BIN1_MOUSE
NC score	0.008422 (rank : 447)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	269	Target Neighborhood Hits	283	Shared Neighborhood Hits	6
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

FUBP1_MOUSE
NC score	0.008180 (rank : 448)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	269	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

LTB1S_HUMAN
NC score	0.007865 (rank : 449)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	269	Target Neighborhood Hits	502	Shared Neighborhood Hits	12
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.007696 (rank : 450)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	269	Target Neighborhood Hits	553	Shared Neighborhood Hits	13
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SPRE2_MOUSE
NC score	0.005808 (rank : 451)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	269	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

LTBP4_MOUSE
NC score	0.004760 (rank : 452)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	269	Target Neighborhood Hits	607	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TLR12_MOUSE
NC score	0.000006 (rank : 453)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	269	Target Neighborhood Hits	268	Shared Neighborhood Hits	3
SwissProt Accessions	Q6QNU9	Gene names	Tlr12
Domain Architecture	No domain graphic available
Description	Toll-like receptor 12 precursor.