Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : TRAF1_HUMAN

For an explanation of this page, click here

TRAF1_HUMAN
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRAF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRAF1_MOUSE
θ value	0 (rank : 2)	NC score	0.993061 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TRAF2_HUMAN
θ value	1.22964e-73 (rank : 3)	NC score	0.865942 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	402	Shared Neighborhood Hits	24
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	3.57772e-73 (rank : 4)	NC score	0.859397 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	394	Shared Neighborhood Hits	23
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_MOUSE
θ value	5.35859e-61 (rank : 5)	NC score	0.808803 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	476	Shared Neighborhood Hits	42
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF3_HUMAN
θ value	1.55911e-60 (rank : 6)	NC score	0.808186 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	463	Shared Neighborhood Hits	43
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF5_MOUSE
θ value	4.39379e-55 (rank : 7)	NC score	0.811560 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	355	Shared Neighborhood Hits	36
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF5_HUMAN
θ value	2.18062e-54 (rank : 8)	NC score	0.812956 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	396	Shared Neighborhood Hits	42
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF4_HUMAN
θ value	1.85889e-29 (rank : 9)	NC score	0.711458 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	373	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	5.97985e-28 (rank : 10)	NC score	0.711175 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	338	Shared Neighborhood Hits	15
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF6_HUMAN
θ value	1.6852e-22 (rank : 11)	NC score	0.698796 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	267	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	1.86321e-21 (rank : 12)	NC score	0.697186 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	255	Shared Neighborhood Hits	22
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

MEP1A_MOUSE
θ value	0.00020696 (rank : 13)	NC score	0.215192 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1A_HUMAN
θ value	0.0193708 (rank : 14)	NC score	0.182525 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1B_MOUSE
θ value	0.0563607 (rank : 15)	NC score	0.216991 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MYH4_MOUSE
θ value	0.125558 (rank : 16)	NC score	0.044060 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	1476	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

RUFY2_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.040440 (rank : 96)
Query Neighborhood Hits	65	Target Neighborhood Hits	1208	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MYH6_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.044003 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	1501	Shared Neighborhood Hits	46
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.046002 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	1559	Shared Neighborhood Hits	52
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

LRRF2_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.054608 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	791	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

CE290_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.055262 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	1553	Shared Neighborhood Hits	47
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SIAH2_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.060308 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.060301 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TACC3_MOUSE
θ value	0.365318 (rank : 24)	NC score	0.064489 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	607	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

CP250_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.041372 (rank : 93)
Query Neighborhood Hits	65	Target Neighborhood Hits	1805	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DIDO1_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.018526 (rank : 117)
Query Neighborhood Hits	65	Target Neighborhood Hits	960	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CKAP4_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.048209 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CP135_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.043963 (rank : 90)
Query Neighborhood Hits	65	Target Neighborhood Hits	1278	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

AKAP9_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.050795 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	1710	Shared Neighborhood Hits	46
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GOGA1_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.030600 (rank : 106)
Query Neighborhood Hits	65	Target Neighborhood Hits	1222	Shared Neighborhood Hits	42
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

KIF17_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.012918 (rank : 120)
Query Neighborhood Hits	65	Target Neighborhood Hits	452	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LAMB1_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.018734 (rank : 116)
Query Neighborhood Hits	65	Target Neighborhood Hits	919	Shared Neighborhood Hits	39
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYH6_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.042195 (rank : 92)
Query Neighborhood Hits	65	Target Neighborhood Hits	1426	Shared Neighborhood Hits	47
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NIN_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.041084 (rank : 94)
Query Neighborhood Hits	65	Target Neighborhood Hits	1416	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RAB6C_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.006112 (rank : 124)
Query Neighborhood Hits	65	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0N0, Q9P128	Gene names	RAB6C, WTH3
Domain Architecture
Description	Ras-related protein Rab-6C (Rab6-like protein WTH3).

ROCK1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.020732 (rank : 115)
Query Neighborhood Hits	65	Target Neighborhood Hits	2000	Shared Neighborhood Hits	44
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

CTRO_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.024734 (rank : 110)
Query Neighborhood Hits	65	Target Neighborhood Hits	2344	Shared Neighborhood Hits	48
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

RUFY2_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.035412 (rank : 102)
Query Neighborhood Hits	65	Target Neighborhood Hits	820	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CCD62_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.034607 (rank : 104)
Query Neighborhood Hits	65	Target Neighborhood Hits	631	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CF060_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.044215 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	1270	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

GOGA6_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.052908 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	1007	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

ROCK1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.017767 (rank : 118)
Query Neighborhood Hits	65	Target Neighborhood Hits	2126	Shared Neighborhood Hits	42
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

CCD46_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.029589 (rank : 107)
Query Neighborhood Hits	65	Target Neighborhood Hits	1430	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CK5P2_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.039795 (rank : 97)
Query Neighborhood Hits	65	Target Neighborhood Hits	1151	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

COG7_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.022584 (rank : 112)
Query Neighborhood Hits	65	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

CRIM1_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.011699 (rank : 121)
Query Neighborhood Hits	65	Target Neighborhood Hits	362	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CTRO_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.022202 (rank : 113)
Query Neighborhood Hits	65	Target Neighborhood Hits	2092	Shared Neighborhood Hits	47
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GOGB1_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.044367 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	2297	Shared Neighborhood Hits	51
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MACF1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.034637 (rank : 103)
Query Neighborhood Hits	65	Target Neighborhood Hits	1341	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.038478 (rank : 99)
Query Neighborhood Hits	65	Target Neighborhood Hits	1321	Shared Neighborhood Hits	47
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYH1_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.044096 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	1461	Shared Neighborhood Hits	49
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

SYTL1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.005287 (rank : 125)
Query Neighborhood Hits	65	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

TARA_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.022701 (rank : 111)
Query Neighborhood Hits	65	Target Neighborhood Hits	1133	Shared Neighborhood Hits	35
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCHCR_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.029124 (rank : 108)
Query Neighborhood Hits	65	Target Neighborhood Hits	932	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

GOGA4_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.039194 (rank : 98)
Query Neighborhood Hits	65	Target Neighborhood Hits	1939	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

TARA_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.017110 (rank : 119)
Query Neighborhood Hits	65	Target Neighborhood Hits	1626	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

EMIL1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.007694 (rank : 123)
Query Neighborhood Hits	65	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

HOOK1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.040758 (rank : 95)
Query Neighborhood Hits	65	Target Neighborhood Hits	942	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK2_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.027654 (rank : 109)
Query Neighborhood Hits	65	Target Neighborhood Hits	714	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

I20RA_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.007940 (rank : 122)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHF4, Q6UWA9, Q96SH8	Gene names	IL20RA, ZCYTOR7
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL-20R1) (Cytokine receptor family 2 member 8) (Cytokine receptor class-II member 8) (CRF2-8) (ZcytoR7).

IGBP1_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.020963 (rank : 114)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q61249	Gene names	Igbp1, Pc52
Domain Architecture
Description	Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (Alpha4 phosphoprotein) (Lymphocyte signal transduction molecule alpha 4) (p52).

KNTC2_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.036718 (rank : 101)
Query Neighborhood Hits	65	Target Neighborhood Hits	673	Shared Neighborhood Hits	41
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KTN1_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.042332 (rank : 91)
Query Neighborhood Hits	65	Target Neighborhood Hits	1324	Shared Neighborhood Hits	46
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MY18B_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.037600 (rank : 100)
Query Neighborhood Hits	65	Target Neighborhood Hits	1299	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PLEC1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.032404 (rank : 105)
Query Neighborhood Hits	65	Target Neighborhood Hits	1326	Shared Neighborhood Hits	45
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

BFAR_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.077128 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.072971 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	232	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.073350 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	381	Shared Neighborhood Hits	21
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.070982 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	436	Shared Neighborhood Hits	16
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CEP57_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.052731 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	580	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CKAP4_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.050540 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ERC2_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.052441 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	1156	Shared Neighborhood Hits	44
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.052324 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	1166	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FBX28_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.055130 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

KTN1_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.050486 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	1197	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LIPA3_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.052625 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	828	Shared Neighborhood Hits	43
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LNX1_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.083908 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	379	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.084288 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	377	Shared Neighborhood Hits	10
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.065556 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	389	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.069535 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	407	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MAT1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.054040 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.054979 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MEP1B_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.176297 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

PEX10_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.066260 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PZRN3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.141510 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	461	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.144682 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	447	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.108543 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.082689 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	177	Shared Neighborhood Hits	7
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.072534 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAG1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.104503 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	8
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.105237 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RING1_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.095400 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.093554 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.085388 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.085379 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.164769 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.138552 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	220	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.193016 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	12
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.187645 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF41_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.164391 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.163506 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	224	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.060283 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.063090 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRAF7_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.137336 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	482	Shared Neighborhood Hits	16
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.139611 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	470	Shared Neighborhood Hits	17
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI12_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.060159 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	387	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI22_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.053123 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	396	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI25_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.056154 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	472	Shared Neighborhood Hits	27
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.063439 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	446	Shared Neighborhood Hits	24
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI26_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.053980 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.052317 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI31_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.071780 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	299	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI47_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.058377 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.067355 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	295	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI56_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.053920 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI65_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.055295 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	330	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.055940 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM8_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.056647 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	650	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.057202 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	674	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UHRF1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.060831 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	272	Shared Neighborhood Hits	9
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.060104 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.079035 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.077403 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN313_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.147353 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.154475 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

TRAF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRAF1_MOUSE
NC score	0.993061 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TRAF2_HUMAN
NC score	0.865942 (rank : 3)	θ value	1.22964e-73 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	402	Shared Neighborhood Hits	24
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
NC score	0.859397 (rank : 4)	θ value	3.57772e-73 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	394	Shared Neighborhood Hits	23
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF5_HUMAN
NC score	0.812956 (rank : 5)	θ value	2.18062e-54 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	396	Shared Neighborhood Hits	42
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
NC score	0.811560 (rank : 6)	θ value	4.39379e-55 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	355	Shared Neighborhood Hits	36
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF3_MOUSE
NC score	0.808803 (rank : 7)	θ value	5.35859e-61 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	476	Shared Neighborhood Hits	42
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF3_HUMAN
NC score	0.808186 (rank : 8)	θ value	1.55911e-60 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	463	Shared Neighborhood Hits	43
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF4_HUMAN
NC score	0.711458 (rank : 9)	θ value	1.85889e-29 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	373	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
NC score	0.711175 (rank : 10)	θ value	5.97985e-28 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	338	Shared Neighborhood Hits	15
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF6_HUMAN
NC score	0.698796 (rank : 11)	θ value	1.6852e-22 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	267	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
NC score	0.697186 (rank : 12)	θ value	1.86321e-21 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	255	Shared Neighborhood Hits	22
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

MEP1B_MOUSE
NC score	0.216991 (rank : 13)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1A_MOUSE
NC score	0.215192 (rank : 14)	θ value	0.00020696 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

RN166_HUMAN
NC score	0.193016 (rank : 15)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	12
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.187645 (rank : 16)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	65	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

MEP1A_HUMAN
NC score	0.182525 (rank : 17)	θ value	0.0193708 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1B_HUMAN
NC score	0.176297 (rank : 18)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

RN125_HUMAN
NC score	0.164769 (rank : 19)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	65	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RNF41_HUMAN
NC score	0.164391 (rank : 20)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	65	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.163506 (rank : 21)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	65	Target Neighborhood Hits	224	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

ZN313_MOUSE
NC score	0.154475 (rank : 22)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	65	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ZN313_HUMAN
NC score	0.147353 (rank : 23)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	65	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

PZRN3_MOUSE
NC score	0.144682 (rank : 24)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	447	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.141510 (rank : 25)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	461	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF7_MOUSE
NC score	0.139611 (rank : 26)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	65	Target Neighborhood Hits	470	Shared Neighborhood Hits	17
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

RN125_MOUSE
NC score	0.138552 (rank : 27)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	65	Target Neighborhood Hits	220	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRAF7_HUMAN
NC score	0.137336 (rank : 28)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	65	Target Neighborhood Hits	482	Shared Neighborhood Hits	16
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

PZRN4_HUMAN
NC score	0.108543 (rank : 29)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RAG1_MOUSE
NC score	0.105237 (rank : 30)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	65	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RAG1_HUMAN
NC score	0.104503 (rank : 31)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	8
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RING1_HUMAN
NC score	0.095400 (rank : 32)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	65	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.093554 (rank : 33)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	65	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
NC score	0.085388 (rank : 34)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.085379 (rank : 35)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

LNX1_MOUSE
NC score	0.084288 (rank : 36)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	377	Shared Neighborhood Hits	10
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.083908 (rank : 37)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	379	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

R113A_HUMAN
NC score	0.082689 (rank : 38)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	177	Shared Neighborhood Hits	7
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

UHRF2_HUMAN
NC score	0.079035 (rank : 39)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.077403 (rank : 40)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BFAR_HUMAN
NC score	0.077128 (rank : 41)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BRCA1_HUMAN
NC score	0.073350 (rank : 42)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	381	Shared Neighborhood Hits	21
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BFAR_MOUSE
NC score	0.072971 (rank : 43)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	232	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

R113B_HUMAN
NC score	0.072534 (rank : 44)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRI31_HUMAN
NC score	0.071780 (rank : 45)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	65	Target Neighborhood Hits	299	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

BRCA1_MOUSE
NC score	0.070982 (rank : 46)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	436	Shared Neighborhood Hits	16
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

LNX2_MOUSE
NC score	0.069535 (rank : 47)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	407	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TRI47_MOUSE
NC score	0.067355 (rank : 48)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	65	Target Neighborhood Hits	295	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

PEX10_HUMAN
NC score	0.066260 (rank : 49)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

LNX2_HUMAN
NC score	0.065556 (rank : 50)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	389	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TACC3_MOUSE
NC score	0.064489 (rank : 51)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	607	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TRI25_MOUSE
NC score	0.063439 (rank : 52)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	65	Target Neighborhood Hits	446	Shared Neighborhood Hits	24
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

RNF4_MOUSE
NC score	0.063090 (rank : 53)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	65	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

UHRF1_HUMAN
NC score	0.060831 (rank : 54)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	65	Target Neighborhood Hits	272	Shared Neighborhood Hits	9
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

SIAH2_HUMAN
NC score	0.060308 (rank : 55)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
NC score	0.060301 (rank : 56)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

RNF4_HUMAN
NC score	0.060283 (rank : 57)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	65	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI12_MOUSE
NC score	0.060159 (rank : 58)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	65	Target Neighborhood Hits	387	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

UHRF1_MOUSE
NC score	0.060104 (rank : 59)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

TRI47_HUMAN
NC score	0.058377 (rank : 60)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	65	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRIM8_MOUSE
NC score	0.057202 (rank : 61)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	65	Target Neighborhood Hits	674	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.056647 (rank : 62)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	65	Target Neighborhood Hits	650	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI25_HUMAN
NC score	0.056154 (rank : 63)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	65	Target Neighborhood Hits	472	Shared Neighborhood Hits	27
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI73_HUMAN
NC score	0.055940 (rank : 64)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	65	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI65_HUMAN
NC score	0.055295 (rank : 65)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	65	Target Neighborhood Hits	330	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CE290_HUMAN
NC score	0.055262 (rank : 66)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	1553	Shared Neighborhood Hits	47
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

FBX28_HUMAN
NC score	0.055130 (rank : 67)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

MAT1_MOUSE
NC score	0.054979 (rank : 68)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

LRRF2_HUMAN
NC score	0.054608 (rank : 69)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	791	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MAT1_HUMAN
NC score	0.054040 (rank : 70)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

TRI26_HUMAN
NC score	0.053980 (rank : 71)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	65	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI56_HUMAN
NC score	0.053920 (rank : 72)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI22_HUMAN
NC score	0.053123 (rank : 73)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	65	Target Neighborhood Hits	396	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

GOGA6_HUMAN
NC score	0.052908 (rank : 74)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	1007	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CEP57_MOUSE
NC score	0.052731 (rank : 75)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	580	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

LIPA3_HUMAN
NC score	0.052625 (rank : 76)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	828	Shared Neighborhood Hits	43
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

ERC2_HUMAN
NC score	0.052441 (rank : 77)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	1156	Shared Neighborhood Hits	44
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
NC score	0.052324 (rank : 78)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	1166	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

TRI26_MOUSE
NC score	0.052317 (rank : 79)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

AKAP9_HUMAN
NC score	0.050795 (rank : 80)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	1710	Shared Neighborhood Hits	46
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CKAP4_HUMAN
NC score	0.050540 (rank : 81)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

KTN1_HUMAN
NC score	0.050486 (rank : 82)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	1197	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CKAP4_MOUSE
NC score	0.048209 (rank : 83)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MYH7_HUMAN
NC score	0.046002 (rank : 84)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	1559	Shared Neighborhood Hits	52
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

GOGB1_HUMAN
NC score	0.044367 (rank : 85)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	2297	Shared Neighborhood Hits	51
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CF060_HUMAN
NC score	0.044215 (rank : 86)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	1270	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MYH1_MOUSE
NC score	0.044096 (rank : 87)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	1461	Shared Neighborhood Hits	49
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
NC score	0.044060 (rank : 88)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	1476	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_MOUSE
NC score	0.044003 (rank : 89)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	1501	Shared Neighborhood Hits	46
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CP135_MOUSE
NC score	0.043963 (rank : 90)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	1278	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

KTN1_MOUSE
NC score	0.042332 (rank : 91)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	1324	Shared Neighborhood Hits	46
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH6_HUMAN
NC score	0.042195 (rank : 92)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	1426	Shared Neighborhood Hits	47
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CP250_HUMAN
NC score	0.041372 (rank : 93)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	1805	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

NIN_HUMAN
NC score	0.041084 (rank : 94)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	1416	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

HOOK1_HUMAN
NC score	0.040758 (rank : 95)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	942	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

RUFY2_HUMAN
NC score	0.040440 (rank : 96)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	1208	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CK5P2_MOUSE
NC score	0.039795 (rank : 97)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	1151	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

GOGA4_MOUSE
NC score	0.039194 (rank : 98)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	1939	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MACF4_HUMAN
NC score	0.038478 (rank : 99)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	1321	Shared Neighborhood Hits	47
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MY18B_HUMAN
NC score	0.037600 (rank : 100)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	1299	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

KNTC2_HUMAN
NC score	0.036718 (rank : 101)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	673	Shared Neighborhood Hits	41
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

RUFY2_MOUSE
NC score	0.035412 (rank : 102)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	820	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

MACF1_HUMAN
NC score	0.034637 (rank : 103)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	1341	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

CCD62_HUMAN
NC score	0.034607 (rank : 104)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	631	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

PLEC1_HUMAN
NC score	0.032404 (rank : 105)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	1326	Shared Neighborhood Hits	45
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

GOGA1_HUMAN
NC score	0.030600 (rank : 106)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	1222	Shared Neighborhood Hits	42
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CCD46_HUMAN
NC score	0.029589 (rank : 107)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	1430	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCHCR_MOUSE
NC score	0.029124 (rank : 108)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	932	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

HOOK2_HUMAN
NC score	0.027654 (rank : 109)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	714	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

CTRO_MOUSE
NC score	0.024734 (rank : 110)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	2344	Shared Neighborhood Hits	48
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

TARA_MOUSE
NC score	0.022701 (rank : 111)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	1133	Shared Neighborhood Hits	35
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

COG7_HUMAN
NC score	0.022584 (rank : 112)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

CTRO_HUMAN
NC score	0.022202 (rank : 113)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	2092	Shared Neighborhood Hits	47
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

IGBP1_MOUSE
NC score	0.020963 (rank : 114)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q61249	Gene names	Igbp1, Pc52
Domain Architecture
Description	Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (Alpha4 phosphoprotein) (Lymphocyte signal transduction molecule alpha 4) (p52).

ROCK1_HUMAN
NC score	0.020732 (rank : 115)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	2000	Shared Neighborhood Hits	44
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

LAMB1_MOUSE
NC score	0.018734 (rank : 116)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	919	Shared Neighborhood Hits	39
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

DIDO1_HUMAN
NC score	0.018526 (rank : 117)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	960	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ROCK1_MOUSE
NC score	0.017767 (rank : 118)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	2126	Shared Neighborhood Hits	42
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TARA_HUMAN
NC score	0.017110 (rank : 119)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	1626	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

KIF17_MOUSE
NC score	0.012918 (rank : 120)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	452	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

CRIM1_HUMAN
NC score	0.011699 (rank : 121)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	362	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

I20RA_HUMAN
NC score	0.007940 (rank : 122)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHF4, Q6UWA9, Q96SH8	Gene names	IL20RA, ZCYTOR7
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL-20R1) (Cytokine receptor family 2 member 8) (Cytokine receptor class-II member 8) (CRF2-8) (ZcytoR7).

EMIL1_HUMAN
NC score	0.007694 (rank : 123)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

RAB6C_HUMAN
NC score	0.006112 (rank : 124)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0N0, Q9P128	Gene names	RAB6C, WTH3
Domain Architecture
Description	Ras-related protein Rab-6C (Rab6-like protein WTH3).

SYTL1_HUMAN
NC score	0.005287 (rank : 125)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).