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Network neighborhood for query Sequence : SPRE2_MOUSE

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SPRE2_MOUSE
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPRE2_HUMAN
θ value	0 (rank : 1)	NC score	0.997307 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z698, Q2NKX6	Gene names	SPRED2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE1_MOUSE
θ value	1.02657e-120 (rank : 3)	NC score	0.967219 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE1_HUMAN
θ value	3.90098e-120 (rank : 4)	NC score	0.967590 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z699, Q8N256	Gene names	SPRED1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE3_MOUSE
θ value	6.96618e-77 (rank : 5)	NC score	0.927475 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	111	Shared Neighborhood Hits	21
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE3_HUMAN
θ value	4.22625e-74 (rank : 6)	NC score	0.938231 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

ENAH_MOUSE
θ value	5.08577e-11 (rank : 7)	NC score	0.378621 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	919	Shared Neighborhood Hits	15
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENAH_HUMAN
θ value	6.64225e-11 (rank : 8)	NC score	0.370073 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	784	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SPY3_HUMAN
θ value	4.30538e-10 (rank : 9)	NC score	0.559246 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

SPY2_HUMAN
θ value	2.13673e-09 (rank : 10)	NC score	0.514300 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	66	Shared Neighborhood Hits	14
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
θ value	2.13673e-09 (rank : 11)	NC score	0.513599 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

EVL_HUMAN
θ value	4.76016e-09 (rank : 12)	NC score	0.490195 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_MOUSE
θ value	1.06045e-08 (rank : 13)	NC score	0.485216 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SPY1_HUMAN
θ value	1.06045e-08 (rank : 14)	NC score	0.503587 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

VASP_MOUSE
θ value	1.38499e-08 (rank : 15)	NC score	0.492100 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	195	Shared Neighborhood Hits	12
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_HUMAN
θ value	1.80886e-08 (rank : 16)	NC score	0.475705 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	201	Shared Neighborhood Hits	12
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY4_HUMAN
θ value	4.0297e-08 (rank : 17)	NC score	0.494391 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY4_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.492806 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY1_MOUSE
θ value	8.97725e-08 (rank : 19)	NC score	0.458226 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

PTTG_MOUSE
θ value	0.279714 (rank : 20)	NC score	0.110073 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R143, Q3TVT1, Q8BJ96, Q8N7P0	Gene names	Pttg1ip
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

LPIN2_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.023488 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

FGD3_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.016959 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

PTTG_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.069729 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P53801, Q9NS09	Gene names	PTTG1IP, C21orf1, C21orf3
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

PLXB3_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.018734 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

CLPX_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.014957 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LAMC3_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.015503 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	624	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PRD12_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.000856 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	701	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4Q4	Gene names	PRDM12, PFM9
Domain Architecture
Description	PR domain zinc finger protein 12 (PR domain-containing protein 12).

FGD1_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.011176 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FRAP_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.008942 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

SRA1_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.018237 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VJ2, Q8R0S3, Q9CWU7, Q9D973	Gene names	Sra1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

ZN395_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.018866 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

CCDC9_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.018441 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

FGD1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.010816 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	367	Shared Neighborhood Hits	5
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HNRL1_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.008691 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

PRG4_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.011605 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	624	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

UHRF2_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.005808 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	269	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

WASP_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.070014 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CCDC9_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.020429 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

KIF1B_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.002389 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

PCX1_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.008947 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

TSP3_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.004598 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

HOME3_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.058424 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.058210 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	316	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

WASP_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.061170 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	195	Shared Neighborhood Hits	8
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

Hits sorted by NC score

SPRE2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE2_HUMAN
NC score	0.997307 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z698, Q2NKX6	Gene names	SPRED2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE1_HUMAN
NC score	0.967590 (rank : 3)	θ value	3.90098e-120 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z699, Q8N256	Gene names	SPRED1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE1_MOUSE
NC score	0.967219 (rank : 4)	θ value	1.02657e-120 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE3_HUMAN
NC score	0.938231 (rank : 5)	θ value	4.22625e-74 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE3_MOUSE
NC score	0.927475 (rank : 6)	θ value	6.96618e-77 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	111	Shared Neighborhood Hits	21
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPY3_HUMAN
NC score	0.559246 (rank : 7)	θ value	4.30538e-10 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

SPY2_HUMAN
NC score	0.514300 (rank : 8)	θ value	2.13673e-09 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	66	Shared Neighborhood Hits	14
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
NC score	0.513599 (rank : 9)	θ value	2.13673e-09 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY1_HUMAN
NC score	0.503587 (rank : 10)	θ value	1.06045e-08 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SPY4_HUMAN
NC score	0.494391 (rank : 11)	θ value	4.0297e-08 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY4_MOUSE
NC score	0.492806 (rank : 12)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

VASP_MOUSE
NC score	0.492100 (rank : 13)	θ value	1.38499e-08 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	195	Shared Neighborhood Hits	12
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

EVL_HUMAN
NC score	0.490195 (rank : 14)	θ value	4.76016e-09 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_MOUSE
NC score	0.485216 (rank : 15)	θ value	1.06045e-08 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

VASP_HUMAN
NC score	0.475705 (rank : 16)	θ value	1.80886e-08 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	201	Shared Neighborhood Hits	12
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY1_MOUSE
NC score	0.458226 (rank : 17)	θ value	8.97725e-08 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ENAH_MOUSE
NC score	0.378621 (rank : 18)	θ value	5.08577e-11 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	919	Shared Neighborhood Hits	15
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENAH_HUMAN
NC score	0.370073 (rank : 19)	θ value	6.64225e-11 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	784	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PTTG_MOUSE
NC score	0.110073 (rank : 20)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R143, Q3TVT1, Q8BJ96, Q8N7P0	Gene names	Pttg1ip
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

WASP_MOUSE
NC score	0.070014 (rank : 21)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

PTTG_HUMAN
NC score	0.069729 (rank : 22)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P53801, Q9NS09	Gene names	PTTG1IP, C21orf1, C21orf3
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

WASP_HUMAN
NC score	0.061170 (rank : 23)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	195	Shared Neighborhood Hits	8
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

HOME3_HUMAN
NC score	0.058424 (rank : 24)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_MOUSE
NC score	0.058210 (rank : 25)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	316	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

LPIN2_HUMAN
NC score	0.023488 (rank : 26)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

CCDC9_MOUSE
NC score	0.020429 (rank : 27)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

ZN395_HUMAN
NC score	0.018866 (rank : 28)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

PLXB3_MOUSE
NC score	0.018734 (rank : 29)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

CCDC9_HUMAN
NC score	0.018441 (rank : 30)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

SRA1_MOUSE
NC score	0.018237 (rank : 31)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VJ2, Q8R0S3, Q9CWU7, Q9D973	Gene names	Sra1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

FGD3_HUMAN
NC score	0.016959 (rank : 32)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

LAMC3_MOUSE
NC score	0.015503 (rank : 33)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	624	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CLPX_MOUSE
NC score	0.014957 (rank : 34)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

PRG4_MOUSE
NC score	0.011605 (rank : 35)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	624	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

FGD1_MOUSE
NC score	0.011176 (rank : 36)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.010816 (rank : 37)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	367	Shared Neighborhood Hits	5
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PCX1_HUMAN
NC score	0.008947 (rank : 38)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

FRAP_HUMAN
NC score	0.008942 (rank : 39)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

HNRL1_MOUSE
NC score	0.008691 (rank : 40)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

UHRF2_HUMAN
NC score	0.005808 (rank : 41)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	269	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

TSP3_MOUSE
NC score	0.004598 (rank : 42)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

KIF1B_HUMAN
NC score	0.002389 (rank : 43)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

PRD12_HUMAN
NC score	0.000856 (rank : 44)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	701	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4Q4	Gene names	PRDM12, PFM9
Domain Architecture
Description	PR domain zinc finger protein 12 (PR domain-containing protein 12).