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Network neighborhood for query Sequence : RN133_HUMAN

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RN133_HUMAN
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RN133_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	108	Target Neighborhood Hits	108	Shared Neighborhood Hits	108
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

GOLI_HUMAN
θ value	1.73182e-43 (rank : 2)	NC score	0.907539 (rank : 3)
Query Neighborhood Hits	108	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	2.26182e-43 (rank : 3)	NC score	0.908684 (rank : 2)
Query Neighborhood Hits	108	Target Neighborhood Hits	134	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

RNF13_MOUSE
θ value	3.63628e-17 (rank : 4)	NC score	0.782486 (rank : 4)
Query Neighborhood Hits	108	Target Neighborhood Hits	164	Shared Neighborhood Hits	90
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
θ value	6.85773e-16 (rank : 5)	NC score	0.775334 (rank : 5)
Query Neighborhood Hits	108	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RN167_HUMAN
θ value	2.43908e-13 (rank : 6)	NC score	0.767344 (rank : 7)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	3.18553e-13 (rank : 7)	NC score	0.767819 (rank : 6)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

ZN364_MOUSE
θ value	1.06045e-08 (rank : 8)	NC score	0.667225 (rank : 15)
Query Neighborhood Hits	108	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

DZIP3_MOUSE
θ value	1.80886e-08 (rank : 9)	NC score	0.508189 (rank : 30)
Query Neighborhood Hits	108	Target Neighborhood Hits	414	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

RNF24_MOUSE
θ value	2.36244e-08 (rank : 10)	NC score	0.696215 (rank : 10)
Query Neighborhood Hits	108	Target Neighborhood Hits	124	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
θ value	4.0297e-08 (rank : 11)	NC score	0.694886 (rank : 11)
Query Neighborhood Hits	108	Target Neighborhood Hits	122	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF38_HUMAN
θ value	4.0297e-08 (rank : 12)	NC score	0.659094 (rank : 17)
Query Neighborhood Hits	108	Target Neighborhood Hits	155	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ZN364_HUMAN
θ value	4.0297e-08 (rank : 13)	NC score	0.667021 (rank : 16)
Query Neighborhood Hits	108	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

DZIP3_HUMAN
θ value	5.26297e-08 (rank : 14)	NC score	0.497333 (rank : 31)
Query Neighborhood Hits	108	Target Neighborhood Hits	399	Shared Neighborhood Hits	70
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

PJA1_MOUSE
θ value	8.97725e-08 (rank : 15)	NC score	0.616846 (rank : 24)
Query Neighborhood Hits	108	Target Neighborhood Hits	145	Shared Neighborhood Hits	75
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RNF38_MOUSE
θ value	1.53129e-07 (rank : 16)	NC score	0.654322 (rank : 19)
Query Neighborhood Hits	108	Target Neighborhood Hits	153	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN126_MOUSE
θ value	1.99992e-07 (rank : 17)	NC score	0.658878 (rank : 18)
Query Neighborhood Hits	108	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN165_HUMAN
θ value	1.99992e-07 (rank : 18)	NC score	0.712072 (rank : 8)
Query Neighborhood Hits	108	Target Neighborhood Hits	151	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

PJA1_HUMAN
θ value	2.61198e-07 (rank : 19)	NC score	0.597471 (rank : 25)
Query Neighborhood Hits	108	Target Neighborhood Hits	159	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RN126_HUMAN
θ value	7.59969e-07 (rank : 20)	NC score	0.645764 (rank : 21)
Query Neighborhood Hits	108	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF12_MOUSE
θ value	7.59969e-07 (rank : 21)	NC score	0.652947 (rank : 20)
Query Neighborhood Hits	108	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RN122_HUMAN
θ value	2.88788e-06 (rank : 22)	NC score	0.693509 (rank : 12)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	2.88788e-06 (rank : 23)	NC score	0.696911 (rank : 9)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF12_HUMAN
θ value	6.43352e-06 (rank : 24)	NC score	0.629221 (rank : 23)
Query Neighborhood Hits	108	Target Neighborhood Hits	173	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

AMFR2_HUMAN
θ value	8.40245e-06 (rank : 25)	NC score	0.519473 (rank : 28)
Query Neighborhood Hits	108	Target Neighborhood Hits	219	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	8.40245e-06 (rank : 26)	NC score	0.523690 (rank : 27)
Query Neighborhood Hits	108	Target Neighborhood Hits	208	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

RNF6_HUMAN
θ value	8.40245e-06 (rank : 27)	NC score	0.638436 (rank : 22)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF11_HUMAN
θ value	1.43324e-05 (rank : 28)	NC score	0.680497 (rank : 13)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	1.43324e-05 (rank : 29)	NC score	0.678497 (rank : 14)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RN139_HUMAN
θ value	7.1131e-05 (rank : 30)	NC score	0.531750 (rank : 26)
Query Neighborhood Hits	108	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

TTC3_HUMAN
θ value	0.00020696 (rank : 31)	NC score	0.296935 (rank : 45)
Query Neighborhood Hits	108	Target Neighborhood Hits	664	Shared Neighborhood Hits	62
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RN139_MOUSE
θ value	0.000461057 (rank : 32)	NC score	0.516818 (rank : 29)
Query Neighborhood Hits	108	Target Neighborhood Hits	131	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

ZSWM2_HUMAN
θ value	0.000786445 (rank : 33)	NC score	0.435138 (rank : 37)
Query Neighborhood Hits	108	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN103_HUMAN
θ value	0.00134147 (rank : 34)	NC score	0.476251 (rank : 33)
Query Neighborhood Hits	108	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.00134147 (rank : 35)	NC score	0.479366 (rank : 32)
Query Neighborhood Hits	108	Target Neighborhood Hits	143	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

ZSWM2_MOUSE
θ value	0.00175202 (rank : 36)	NC score	0.462647 (rank : 34)
Query Neighborhood Hits	108	Target Neighborhood Hits	132	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

MGRN1_HUMAN
θ value	0.00298849 (rank : 37)	NC score	0.201842 (rank : 64)
Query Neighborhood Hits	108	Target Neighborhood Hits	192	Shared Neighborhood Hits	39
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

RBX2_HUMAN
θ value	0.0113563 (rank : 38)	NC score	0.370069 (rank : 39)
Query Neighborhood Hits	108	Target Neighborhood Hits	83	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	0.0113563 (rank : 39)	NC score	0.370882 (rank : 38)
Query Neighborhood Hits	108	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

TRIM2_HUMAN
θ value	0.0193708 (rank : 40)	NC score	0.176006 (rank : 71)
Query Neighborhood Hits	108	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.0193708 (rank : 41)	NC score	0.175698 (rank : 72)
Query Neighborhood Hits	108	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RN141_HUMAN
θ value	0.0252991 (rank : 42)	NC score	0.457665 (rank : 36)
Query Neighborhood Hits	108	Target Neighborhood Hits	199	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.0252991 (rank : 43)	NC score	0.458584 (rank : 35)
Query Neighborhood Hits	108	Target Neighborhood Hits	200	Shared Neighborhood Hits	71
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF8_HUMAN
θ value	0.0330416 (rank : 44)	NC score	0.235400 (rank : 54)
Query Neighborhood Hits	108	Target Neighborhood Hits	622	Shared Neighborhood Hits	78
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRIM3_MOUSE
θ value	0.0563607 (rank : 45)	NC score	0.149254 (rank : 77)
Query Neighborhood Hits	108	Target Neighborhood Hits	351	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

BRAP_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.218138 (rank : 55)
Query Neighborhood Hits	108	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.0961366 (rank : 47)	NC score	0.245428 (rank : 49)
Query Neighborhood Hits	108	Target Neighborhood Hits	409	Shared Neighborhood Hits	57
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CBLC_MOUSE
θ value	0.0961366 (rank : 48)	NC score	0.238747 (rank : 52)
Query Neighborhood Hits	108	Target Neighborhood Hits	186	Shared Neighborhood Hits	59
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	0.0961366 (rank : 49)	NC score	0.213976 (rank : 58)
Query Neighborhood Hits	108	Target Neighborhood Hits	353	Shared Neighborhood Hits	59
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0961366 (rank : 50)	NC score	0.209794 (rank : 59)
Query Neighborhood Hits	108	Target Neighborhood Hits	426	Shared Neighborhood Hits	61
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

PAP21_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.119117 (rank : 93)
Query Neighborhood Hits	108	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BSG0	Gene names	PAP21, C2orf7
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor (hPAP21).

PAP21_MOUSE
θ value	0.0961366 (rank : 52)	NC score	0.119148 (rank : 92)
Query Neighborhood Hits	108	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D9N8	Gene names	Pap21
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor.

PSL1_MOUSE
θ value	0.0961366 (rank : 53)	NC score	0.069356 (rank : 118)
Query Neighborhood Hits	108	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

TRAIP_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.188425 (rank : 69)
Query Neighborhood Hits	108	Target Neighborhood Hits	780	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.188287 (rank : 70)
Query Neighborhood Hits	108	Target Neighborhood Hits	745	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ABCA6_MOUSE
θ value	0.125558 (rank : 56)	NC score	0.018351 (rank : 162)
Query Neighborhood Hits	108	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

CHFR_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.280916 (rank : 48)
Query Neighborhood Hits	108	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.125558 (rank : 58)	NC score	0.282171 (rank : 47)
Query Neighborhood Hits	108	Target Neighborhood Hits	264	Shared Neighborhood Hits	68
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF8_MOUSE
θ value	0.125558 (rank : 59)	NC score	0.241097 (rank : 50)
Query Neighborhood Hits	108	Target Neighborhood Hits	618	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

MGRN1_MOUSE
θ value	0.163984 (rank : 60)	NC score	0.190925 (rank : 68)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

CBLB_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.205338 (rank : 60)
Query Neighborhood Hits	108	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.21417 (rank : 62)	NC score	0.204657 (rank : 61)
Query Neighborhood Hits	108	Target Neighborhood Hits	277	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

RNF32_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.364908 (rank : 40)
Query Neighborhood Hits	108	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

PSL1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.055253 (rank : 148)
Query Neighborhood Hits	108	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RNF32_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.345659 (rank : 41)
Query Neighborhood Hits	108	Target Neighborhood Hits	129	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

ZN363_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.333606 (rank : 43)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.344610 (rank : 42)
Query Neighborhood Hits	108	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

EDEM3_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.086332 (rank : 110)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

ZN294_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.121585 (rank : 90)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

MYCB2_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.104040 (rank : 101)
Query Neighborhood Hits	108	Target Neighborhood Hits	390	Shared Neighborhood Hits	35
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TRIM3_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.148449 (rank : 78)
Query Neighborhood Hits	108	Target Neighborhood Hits	357	Shared Neighborhood Hits	58
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

ZN294_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.120258 (rank : 91)
Query Neighborhood Hits	108	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

PCGF4_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.143675 (rank : 81)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.141979 (rank : 83)
Query Neighborhood Hits	108	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

SMRA3_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.069893 (rank : 117)
Query Neighborhood Hits	108	Target Neighborhood Hits	265	Shared Neighborhood Hits	47
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TOPRS_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.237638 (rank : 53)
Query Neighborhood Hits	108	Target Neighborhood Hits	286	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.240536 (rank : 51)
Query Neighborhood Hits	108	Target Neighborhood Hits	263	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

MYCB2_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.105550 (rank : 99)
Query Neighborhood Hits	108	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

CBLC_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.192987 (rank : 67)
Query Neighborhood Hits	108	Target Neighborhood Hits	173	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CHD4_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.046029 (rank : 152)
Query Neighborhood Hits	108	Target Neighborhood Hits	365	Shared Neighborhood Hits	19
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.045609 (rank : 153)
Query Neighborhood Hits	108	Target Neighborhood Hits	408	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

RN175_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.319305 (rank : 44)
Query Neighborhood Hits	108	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

UHRF2_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.046750 (rank : 151)
Query Neighborhood Hits	108	Target Neighborhood Hits	269	Shared Neighborhood Hits	31
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ATX1_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.021838 (rank : 160)
Query Neighborhood Hits	108	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

LRSM1_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.023923 (rank : 159)
Query Neighborhood Hits	108	Target Neighborhood Hits	1078	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PF21A_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.056769 (rank : 144)
Query Neighborhood Hits	108	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PZRN3_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.094934 (rank : 109)
Query Neighborhood Hits	108	Target Neighborhood Hits	461	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.095065 (rank : 108)
Query Neighborhood Hits	108	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TFR2_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.019778 (rank : 161)
Query Neighborhood Hits	108	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKX3, Q920I6, Q99MQ9, Q9CPT2	Gene names	Tfr2, Trfr2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

MLL3_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.030237 (rank : 158)
Query Neighborhood Hits	108	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RNF4_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.215433 (rank : 57)
Query Neighborhood Hits	108	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

CHD3_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.045477 (rank : 154)
Query Neighborhood Hits	108	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ASPP1_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.003144 (rank : 166)
Query Neighborhood Hits	108	Target Neighborhood Hits	1244	Shared Neighborhood Hits	8
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CM007_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.139948 (rank : 84)
Query Neighborhood Hits	108	Target Neighborhood Hits	416	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DPOG1_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.016747 (rank : 163)
Query Neighborhood Hits	108	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P54099, Q9JI28	Gene names	Polg, Polg1
Domain Architecture
Description	DNA polymerase subunit gamma 1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha).

LRSM1_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.032658 (rank : 157)
Query Neighborhood Hits	108	Target Neighborhood Hits	874	Shared Neighborhood Hits	36
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PCGF2_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.144778 (rank : 80)
Query Neighborhood Hits	108	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.145182 (rank : 79)
Query Neighborhood Hits	108	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

RNF25_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.155148 (rank : 76)
Query Neighborhood Hits	108	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RNF25_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.169777 (rank : 75)
Query Neighborhood Hits	108	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF26_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.112136 (rank : 94)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

CHD5_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.042664 (rank : 156)
Query Neighborhood Hits	108	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

PEX10_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.286909 (rank : 46)
Query Neighborhood Hits	108	Target Neighborhood Hits	255	Shared Neighborhood Hits	81
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PF21A_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.044895 (rank : 155)
Query Neighborhood Hits	108	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

SMRA3_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.067996 (rank : 122)
Query Neighborhood Hits	108	Target Neighborhood Hits	267	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TFR2_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.015638 (rank : 165)
Query Neighborhood Hits	108	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP52, O75422, Q9HA99, Q9NX67	Gene names	TFR2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

VPS41_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.016569 (rank : 164)
Query Neighborhood Hits	108	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

ZN645_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.061382 (rank : 135)
Query Neighborhood Hits	108	Target Neighborhood Hits	265	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

AMFR1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.064331 (rank : 128)
Query Neighborhood Hits	108	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P26442	Gene names	AMFR
Domain Architecture	No domain graphic available
Description	Autocrine motility factor receptor precursor, isoform 1 (AMF receptor).

APC11_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.204046 (rank : 63)
Query Neighborhood Hits	108	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

APC11_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.216318 (rank : 56)
Query Neighborhood Hits	108	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

BFAR_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.063022 (rank : 133)
Query Neighborhood Hits	108	Target Neighborhood Hits	222	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.071154 (rank : 116)
Query Neighborhood Hits	108	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CM007_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.123189 (rank : 88)
Query Neighborhood Hits	108	Target Neighborhood Hits	422	Shared Neighborhood Hits	57
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

DTX3L_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.098626 (rank : 105)
Query Neighborhood Hits	108	Target Neighborhood Hits	187	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.106399 (rank : 98)
Query Neighborhood Hits	108	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.101835 (rank : 103)
Query Neighborhood Hits	108	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

NHLC1_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.051419 (rank : 150)
Query Neighborhood Hits	108	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF6_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.059908 (rank : 139)
Query Neighborhood Hits	108	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.060556 (rank : 137)
Query Neighborhood Hits	108	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN4_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.063172 (rank : 132)
Query Neighborhood Hits	108	Target Neighborhood Hits	438	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RAD18_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.106582 (rank : 96)
Query Neighborhood Hits	108	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.106456 (rank : 97)
Query Neighborhood Hits	108	Target Neighborhood Hits	230	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAPSN_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.175598 (rank : 73)
Query Neighborhood Hits	108	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.173205 (rank : 74)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	44
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RBX1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.200239 (rank : 65)
Query Neighborhood Hits	108	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.200239 (rank : 66)
Query Neighborhood Hits	108	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

RING1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.075295 (rank : 113)
Query Neighborhood Hits	108	Target Neighborhood Hits	219	Shared Neighborhood Hits	41
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.073995 (rank : 114)
Query Neighborhood Hits	108	Target Neighborhood Hits	220	Shared Neighborhood Hits	42
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.068097 (rank : 121)
Query Neighborhood Hits	108	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.068244 (rank : 119)
Query Neighborhood Hits	108	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.095943 (rank : 106)
Query Neighborhood Hits	108	Target Neighborhood Hits	230	Shared Neighborhood Hits	46
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.064161 (rank : 129)
Query Neighborhood Hits	108	Target Neighborhood Hits	220	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN146_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.062381 (rank : 134)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.057824 (rank : 142)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN166_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.066814 (rank : 124)
Query Neighborhood Hits	108	Target Neighborhood Hits	240	Shared Neighborhood Hits	42
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.066974 (rank : 123)
Query Neighborhood Hits	108	Target Neighborhood Hits	248	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.055755 (rank : 146)
Query Neighborhood Hits	108	Target Neighborhood Hits	370	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.056099 (rank : 145)
Query Neighborhood Hits	108	Target Neighborhood Hits	440	Shared Neighborhood Hits	37
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN185_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.142521 (rank : 82)
Query Neighborhood Hits	108	Target Neighborhood Hits	213	Shared Neighborhood Hits	55
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.134099 (rank : 87)
Query Neighborhood Hits	108	Target Neighborhood Hits	211	Shared Neighborhood Hits	53
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF37_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.054301 (rank : 149)
Query Neighborhood Hits	108	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

RNF41_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.137237 (rank : 86)
Query Neighborhood Hits	108	Target Neighborhood Hits	226	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.137327 (rank : 85)
Query Neighborhood Hits	108	Target Neighborhood Hits	224	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.204159 (rank : 62)
Query Neighborhood Hits	108	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.105104 (rank : 100)
Query Neighborhood Hits	108	Target Neighborhood Hits	206	Shared Neighborhood Hits	49
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.102515 (rank : 102)
Query Neighborhood Hits	108	Target Neighborhood Hits	206	Shared Neighborhood Hits	49
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI13_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.083334 (rank : 112)
Query Neighborhood Hits	108	Target Neighborhood Hits	274	Shared Neighborhood Hits	59
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.085950 (rank : 111)
Query Neighborhood Hits	108	Target Neighborhood Hits	282	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI35_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.068149 (rank : 120)
Query Neighborhood Hits	108	Target Neighborhood Hits	382	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.065861 (rank : 126)
Query Neighborhood Hits	108	Target Neighborhood Hits	465	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.063747 (rank : 131)
Query Neighborhood Hits	108	Target Neighborhood Hits	307	Shared Neighborhood Hits	30
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.063774 (rank : 130)
Query Neighborhood Hits	108	Target Neighborhood Hits	316	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI39_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.057956 (rank : 141)
Query Neighborhood Hits	108	Target Neighborhood Hits	693	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.056794 (rank : 143)
Query Neighborhood Hits	108	Target Neighborhood Hits	691	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI40_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.058555 (rank : 140)
Query Neighborhood Hits	108	Target Neighborhood Hits	279	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI56_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.071841 (rank : 115)
Query Neighborhood Hits	108	Target Neighborhood Hits	339	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.055317 (rank : 147)
Query Neighborhood Hits	108	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI59_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.060052 (rank : 138)
Query Neighborhood Hits	108	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.061327 (rank : 136)
Query Neighborhood Hits	108	Target Neighborhood Hits	292	Shared Neighborhood Hits	49
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI65_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.122223 (rank : 89)
Query Neighborhood Hits	108	Target Neighborhood Hits	330	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.106640 (rank : 95)
Query Neighborhood Hits	108	Target Neighborhood Hits	340	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

VPS11_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.065621 (rank : 127)
Query Neighborhood Hits	108	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.066193 (rank : 125)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

ZN313_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.100723 (rank : 104)
Query Neighborhood Hits	108	Target Neighborhood Hits	264	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.095270 (rank : 107)
Query Neighborhood Hits	108	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

RN133_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	108	Target Neighborhood Hits	108	Shared Neighborhood Hits	108
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

GOLI_MOUSE
NC score	0.908684 (rank : 2)	θ value	2.26182e-43 (rank : 3)
Query Neighborhood Hits	108	Target Neighborhood Hits	134	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
NC score	0.907539 (rank : 3)	θ value	1.73182e-43 (rank : 2)
Query Neighborhood Hits	108	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF13_MOUSE
NC score	0.782486 (rank : 4)	θ value	3.63628e-17 (rank : 4)
Query Neighborhood Hits	108	Target Neighborhood Hits	164	Shared Neighborhood Hits	90
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
NC score	0.775334 (rank : 5)	θ value	6.85773e-16 (rank : 5)
Query Neighborhood Hits	108	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RN167_MOUSE
NC score	0.767819 (rank : 6)	θ value	3.18553e-13 (rank : 7)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_HUMAN
NC score	0.767344 (rank : 7)	θ value	2.43908e-13 (rank : 6)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN165_HUMAN
NC score	0.712072 (rank : 8)	θ value	1.99992e-07 (rank : 18)
Query Neighborhood Hits	108	Target Neighborhood Hits	151	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN122_MOUSE
NC score	0.696911 (rank : 9)	θ value	2.88788e-06 (rank : 23)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF24_MOUSE
NC score	0.696215 (rank : 10)	θ value	2.36244e-08 (rank : 10)
Query Neighborhood Hits	108	Target Neighborhood Hits	124	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.694886 (rank : 11)	θ value	4.0297e-08 (rank : 11)
Query Neighborhood Hits	108	Target Neighborhood Hits	122	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RN122_HUMAN
NC score	0.693509 (rank : 12)	θ value	2.88788e-06 (rank : 22)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF11_HUMAN
NC score	0.680497 (rank : 13)	θ value	1.43324e-05 (rank : 28)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.678497 (rank : 14)	θ value	1.43324e-05 (rank : 29)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

ZN364_MOUSE
NC score	0.667225 (rank : 15)	θ value	1.06045e-08 (rank : 8)
Query Neighborhood Hits	108	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZN364_HUMAN
NC score	0.667021 (rank : 16)	θ value	4.0297e-08 (rank : 13)
Query Neighborhood Hits	108	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RNF38_HUMAN
NC score	0.659094 (rank : 17)	θ value	4.0297e-08 (rank : 12)
Query Neighborhood Hits	108	Target Neighborhood Hits	155	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN126_MOUSE
NC score	0.658878 (rank : 18)	θ value	1.99992e-07 (rank : 17)
Query Neighborhood Hits	108	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF38_MOUSE
NC score	0.654322 (rank : 19)	θ value	1.53129e-07 (rank : 16)
Query Neighborhood Hits	108	Target Neighborhood Hits	153	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF12_MOUSE
NC score	0.652947 (rank : 20)	θ value	7.59969e-07 (rank : 21)
Query Neighborhood Hits	108	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RN126_HUMAN
NC score	0.645764 (rank : 21)	θ value	7.59969e-07 (rank : 20)
Query Neighborhood Hits	108	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF6_HUMAN
NC score	0.638436 (rank : 22)	θ value	8.40245e-06 (rank : 27)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF12_HUMAN
NC score	0.629221 (rank : 23)	θ value	6.43352e-06 (rank : 24)
Query Neighborhood Hits	108	Target Neighborhood Hits	173	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

PJA1_MOUSE
NC score	0.616846 (rank : 24)	θ value	8.97725e-08 (rank : 15)
Query Neighborhood Hits	108	Target Neighborhood Hits	145	Shared Neighborhood Hits	75
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PJA1_HUMAN
NC score	0.597471 (rank : 25)	θ value	2.61198e-07 (rank : 19)
Query Neighborhood Hits	108	Target Neighborhood Hits	159	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RN139_HUMAN
NC score	0.531750 (rank : 26)	θ value	7.1131e-05 (rank : 30)
Query Neighborhood Hits	108	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

AMFR_MOUSE
NC score	0.523690 (rank : 27)	θ value	8.40245e-06 (rank : 26)
Query Neighborhood Hits	108	Target Neighborhood Hits	208	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.519473 (rank : 28)	θ value	8.40245e-06 (rank : 25)
Query Neighborhood Hits	108	Target Neighborhood Hits	219	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN139_MOUSE
NC score	0.516818 (rank : 29)	θ value	0.000461057 (rank : 32)
Query Neighborhood Hits	108	Target Neighborhood Hits	131	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

DZIP3_MOUSE
NC score	0.508189 (rank : 30)	θ value	1.80886e-08 (rank : 9)
Query Neighborhood Hits	108	Target Neighborhood Hits	414	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.497333 (rank : 31)	θ value	5.26297e-08 (rank : 14)
Query Neighborhood Hits	108	Target Neighborhood Hits	399	Shared Neighborhood Hits	70
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RN103_MOUSE
NC score	0.479366 (rank : 32)	θ value	0.00134147 (rank : 35)
Query Neighborhood Hits	108	Target Neighborhood Hits	143	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN103_HUMAN
NC score	0.476251 (rank : 33)	θ value	0.00134147 (rank : 34)
Query Neighborhood Hits	108	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

ZSWM2_MOUSE
NC score	0.462647 (rank : 34)	θ value	0.00175202 (rank : 36)
Query Neighborhood Hits	108	Target Neighborhood Hits	132	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN141_MOUSE
NC score	0.458584 (rank : 35)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	108	Target Neighborhood Hits	200	Shared Neighborhood Hits	71
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.457665 (rank : 36)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	108	Target Neighborhood Hits	199	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

ZSWM2_HUMAN
NC score	0.435138 (rank : 37)	θ value	0.000786445 (rank : 33)
Query Neighborhood Hits	108	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RBX2_MOUSE
NC score	0.370882 (rank : 38)	θ value	0.0113563 (rank : 39)
Query Neighborhood Hits	108	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.370069 (rank : 39)	θ value	0.0113563 (rank : 38)
Query Neighborhood Hits	108	Target Neighborhood Hits	83	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RNF32_HUMAN
NC score	0.364908 (rank : 40)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	108	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
NC score	0.345659 (rank : 41)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	108	Target Neighborhood Hits	129	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

ZN363_MOUSE
NC score	0.344610 (rank : 42)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	108	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN363_HUMAN
NC score	0.333606 (rank : 43)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RN175_HUMAN
NC score	0.319305 (rank : 44)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	108	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

TTC3_HUMAN
NC score	0.296935 (rank : 45)	θ value	0.00020696 (rank : 31)
Query Neighborhood Hits	108	Target Neighborhood Hits	664	Shared Neighborhood Hits	62
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

PEX10_HUMAN
NC score	0.286909 (rank : 46)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	108	Target Neighborhood Hits	255	Shared Neighborhood Hits	81
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

CHFR_MOUSE
NC score	0.282171 (rank : 47)	θ value	0.125558 (rank : 58)
Query Neighborhood Hits	108	Target Neighborhood Hits	264	Shared Neighborhood Hits	68
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
NC score	0.280916 (rank : 48)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	108	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

BRAP_MOUSE
NC score	0.245428 (rank : 49)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	108	Target Neighborhood Hits	409	Shared Neighborhood Hits	57
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

RNF8_MOUSE
NC score	0.241097 (rank : 50)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	108	Target Neighborhood Hits	618	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TOPRS_MOUSE
NC score	0.240536 (rank : 51)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	108	Target Neighborhood Hits	263	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CBLC_MOUSE
NC score	0.238747 (rank : 52)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	108	Target Neighborhood Hits	186	Shared Neighborhood Hits	59
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

TOPRS_HUMAN
NC score	0.237638 (rank : 53)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	108	Target Neighborhood Hits	286	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RNF8_HUMAN
NC score	0.235400 (rank : 54)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	108	Target Neighborhood Hits	622	Shared Neighborhood Hits	78
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

BRAP_HUMAN
NC score	0.218138 (rank : 55)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	108	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

APC11_MOUSE
NC score	0.216318 (rank : 56)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	108	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RNF4_HUMAN
NC score	0.215433 (rank : 57)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	108	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

CBL_HUMAN
NC score	0.213976 (rank : 58)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	108	Target Neighborhood Hits	353	Shared Neighborhood Hits	59
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
NC score	0.209794 (rank : 59)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	108	Target Neighborhood Hits	426	Shared Neighborhood Hits	61
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLB_HUMAN
NC score	0.205338 (rank : 60)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	108	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
NC score	0.204657 (rank : 61)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	108	Target Neighborhood Hits	277	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

RNF4_MOUSE
NC score	0.204159 (rank : 62)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	108	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

APC11_HUMAN
NC score	0.204046 (rank : 63)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	108	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

MGRN1_HUMAN
NC score	0.201842 (rank : 64)	θ value	0.00298849 (rank : 37)
Query Neighborhood Hits	108	Target Neighborhood Hits	192	Shared Neighborhood Hits	39
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

RBX1_HUMAN
NC score	0.200239 (rank : 65)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	108	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
NC score	0.200239 (rank : 66)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	108	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

CBLC_HUMAN
NC score	0.192987 (rank : 67)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	108	Target Neighborhood Hits	173	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

MGRN1_MOUSE
NC score	0.190925 (rank : 68)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

TRAIP_HUMAN
NC score	0.188425 (rank : 69)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	108	Target Neighborhood Hits	780	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.188287 (rank : 70)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	108	Target Neighborhood Hits	745	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRIM2_HUMAN
NC score	0.176006 (rank : 71)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	108	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.175698 (rank : 72)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	108	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RAPSN_HUMAN
NC score	0.175598 (rank : 73)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	108	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
NC score	0.173205 (rank : 74)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	44
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RNF25_MOUSE
NC score	0.169777 (rank : 75)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	108	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF25_HUMAN
NC score	0.155148 (rank : 76)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	108	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

TRIM3_MOUSE
NC score	0.149254 (rank : 77)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	108	Target Neighborhood Hits	351	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.148449 (rank : 78)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	108	Target Neighborhood Hits	357	Shared Neighborhood Hits	58
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

PCGF2_MOUSE
NC score	0.145182 (rank : 79)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	108	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.144778 (rank : 80)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	108	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF4_HUMAN
NC score	0.143675 (rank : 81)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

RN185_HUMAN
NC score	0.142521 (rank : 82)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	108	Target Neighborhood Hits	213	Shared Neighborhood Hits	55
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

PCGF4_MOUSE
NC score	0.141979 (rank : 83)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	108	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

CM007_MOUSE
NC score	0.139948 (rank : 84)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	108	Target Neighborhood Hits	416	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RNF41_MOUSE
NC score	0.137327 (rank : 85)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	108	Target Neighborhood Hits	224	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.137237 (rank : 86)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	108	Target Neighborhood Hits	226	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RN185_MOUSE
NC score	0.134099 (rank : 87)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	108	Target Neighborhood Hits	211	Shared Neighborhood Hits	53
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

CM007_HUMAN
NC score	0.123189 (rank : 88)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	108	Target Neighborhood Hits	422	Shared Neighborhood Hits	57
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRI65_HUMAN
NC score	0.122223 (rank : 89)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	108	Target Neighborhood Hits	330	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ZN294_MOUSE
NC score	0.121585 (rank : 90)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

ZN294_HUMAN
NC score	0.120258 (rank : 91)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	108	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

PAP21_MOUSE
NC score	0.119148 (rank : 92)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	108	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D9N8	Gene names	Pap21
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor.

PAP21_HUMAN
NC score	0.119117 (rank : 93)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	108	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BSG0	Gene names	PAP21, C2orf7
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor (hPAP21).

RNF26_HUMAN
NC score	0.112136 (rank : 94)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

TRI65_MOUSE
NC score	0.106640 (rank : 95)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	108	Target Neighborhood Hits	340	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RAD18_HUMAN
NC score	0.106582 (rank : 96)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	108	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
NC score	0.106456 (rank : 97)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	108	Target Neighborhood Hits	230	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

DTX3_HUMAN
NC score	0.106399 (rank : 98)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	108	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

MYCB2_MOUSE
NC score	0.105550 (rank : 99)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	108	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RNF5_HUMAN
NC score	0.105104 (rank : 100)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	108	Target Neighborhood Hits	206	Shared Neighborhood Hits	49
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

MYCB2_HUMAN
NC score	0.104040 (rank : 101)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	108	Target Neighborhood Hits	390	Shared Neighborhood Hits	35
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RNF5_MOUSE
NC score	0.102515 (rank : 102)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	108	Target Neighborhood Hits	206	Shared Neighborhood Hits	49
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

DTX3_MOUSE
NC score	0.101835 (rank : 103)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	108	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ZN313_HUMAN
NC score	0.100723 (rank : 104)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	108	Target Neighborhood Hits	264	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

DTX3L_HUMAN
NC score	0.098626 (rank : 105)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	108	Target Neighborhood Hits	187	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RN125_HUMAN
NC score	0.095943 (rank : 106)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	108	Target Neighborhood Hits	230	Shared Neighborhood Hits	46
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

ZN313_MOUSE
NC score	0.095270 (rank : 107)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	108	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

PZRN3_MOUSE
NC score	0.095065 (rank : 108)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	108	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.094934 (rank : 109)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	108	Target Neighborhood Hits	461	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

EDEM3_HUMAN
NC score	0.086332 (rank : 110)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

TRI13_MOUSE
NC score	0.085950 (rank : 111)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	108	Target Neighborhood Hits	282	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.083334 (rank : 112)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	108	Target Neighborhood Hits	274	Shared Neighborhood Hits	59
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

RING1_HUMAN
NC score	0.075295 (rank : 113)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	108	Target Neighborhood Hits	219	Shared Neighborhood Hits	41
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.073995 (rank : 114)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	108	Target Neighborhood Hits	220	Shared Neighborhood Hits	42
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI56_HUMAN
NC score	0.071841 (rank : 115)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	108	Target Neighborhood Hits	339	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

BFAR_MOUSE
NC score	0.071154 (rank : 116)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	108	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

SMRA3_HUMAN
NC score	0.069893 (rank : 117)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	108	Target Neighborhood Hits	265	Shared Neighborhood Hits	47
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

PSL1_MOUSE
NC score	0.069356 (rank : 118)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	108	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

RING2_MOUSE
NC score	0.068244 (rank : 119)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	108	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRI35_HUMAN
NC score	0.068149 (rank : 120)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	108	Target Neighborhood Hits	382	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

RING2_HUMAN
NC score	0.068097 (rank : 121)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	108	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

SMRA3_MOUSE
NC score	0.067996 (rank : 122)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	108	Target Neighborhood Hits	267	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RN166_MOUSE
NC score	0.066974 (rank : 123)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	108	Target Neighborhood Hits	248	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_HUMAN
NC score	0.066814 (rank : 124)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	108	Target Neighborhood Hits	240	Shared Neighborhood Hits	42
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

VPS11_MOUSE
NC score	0.066193 (rank : 125)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

TRI35_MOUSE
NC score	0.065861 (rank : 126)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	108	Target Neighborhood Hits	465	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

VPS11_HUMAN
NC score	0.065621 (rank : 127)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	108	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

AMFR1_HUMAN
NC score	0.064331 (rank : 128)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	108	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P26442	Gene names	AMFR
Domain Architecture	No domain graphic available
Description	Autocrine motility factor receptor precursor, isoform 1 (AMF receptor).

RN125_MOUSE
NC score	0.064161 (rank : 129)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	108	Target Neighborhood Hits	220	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI37_MOUSE
NC score	0.063774 (rank : 130)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	108	Target Neighborhood Hits	316	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.063747 (rank : 131)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	108	Target Neighborhood Hits	307	Shared Neighborhood Hits	30
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

PZRN4_HUMAN
NC score	0.063172 (rank : 132)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	108	Target Neighborhood Hits	438	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

BFAR_HUMAN
NC score	0.063022 (rank : 133)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	108	Target Neighborhood Hits	222	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN146_HUMAN
NC score	0.062381 (rank : 134)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

ZN645_HUMAN
NC score	0.061382 (rank : 135)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	108	Target Neighborhood Hits	265	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

TRI59_MOUSE
NC score	0.061327 (rank : 136)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	108	Target Neighborhood Hits	292	Shared Neighborhood Hits	49
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

PCGF6_MOUSE
NC score	0.060556 (rank : 137)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	108	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI59_HUMAN
NC score	0.060052 (rank : 138)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	108	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

PCGF6_HUMAN
NC score	0.059908 (rank : 139)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	108	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI40_HUMAN
NC score	0.058555 (rank : 140)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	108	Target Neighborhood Hits	279	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI39_HUMAN
NC score	0.057956 (rank : 141)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	108	Target Neighborhood Hits	693	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RN146_MOUSE
NC score	0.057824 (rank : 142)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI39_MOUSE
NC score	0.056794 (rank : 143)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	108	Target Neighborhood Hits	691	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

PF21A_HUMAN
NC score	0.056769 (rank : 144)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	108	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RN168_MOUSE
NC score	0.056099 (rank : 145)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	108	Target Neighborhood Hits	440	Shared Neighborhood Hits	37
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_HUMAN
NC score	0.055755 (rank : 146)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	108	Target Neighborhood Hits	370	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI56_MOUSE
NC score	0.055317 (rank : 147)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	108	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

PSL1_HUMAN
NC score	0.055253 (rank : 148)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	108	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RNF37_MOUSE
NC score	0.054301 (rank : 149)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	108	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

NHLC1_MOUSE
NC score	0.051419 (rank : 150)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	108	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

UHRF2_HUMAN
NC score	0.046750 (rank : 151)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	108	Target Neighborhood Hits	269	Shared Neighborhood Hits	31
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

CHD4_HUMAN
NC score	0.046029 (rank : 152)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	108	Target Neighborhood Hits	365	Shared Neighborhood Hits	19
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.045609 (rank : 153)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	108	Target Neighborhood Hits	408	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.045477 (rank : 154)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	108	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

PF21A_MOUSE
NC score	0.044895 (rank : 155)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	108	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CHD5_HUMAN
NC score	0.042664 (rank : 156)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	108	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

LRSM1_MOUSE
NC score	0.032658 (rank : 157)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	108	Target Neighborhood Hits	874	Shared Neighborhood Hits	36
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MLL3_MOUSE
NC score	0.030237 (rank : 158)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	108	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LRSM1_HUMAN
NC score	0.023923 (rank : 159)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	108	Target Neighborhood Hits	1078	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ATX1_MOUSE
NC score	0.021838 (rank : 160)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	108	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

TFR2_MOUSE
NC score	0.019778 (rank : 161)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	108	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKX3, Q920I6, Q99MQ9, Q9CPT2	Gene names	Tfr2, Trfr2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

ABCA6_MOUSE
NC score	0.018351 (rank : 162)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	108	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

DPOG1_MOUSE
NC score	0.016747 (rank : 163)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	108	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P54099, Q9JI28	Gene names	Polg, Polg1
Domain Architecture
Description	DNA polymerase subunit gamma 1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha).

VPS41_MOUSE
NC score	0.016569 (rank : 164)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	108	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

TFR2_HUMAN
NC score	0.015638 (rank : 165)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	108	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP52, O75422, Q9HA99, Q9NX67	Gene names	TFR2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

ASPP1_MOUSE
NC score	0.003144 (rank : 166)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	108	Target Neighborhood Hits	1244	Shared Neighborhood Hits	8
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).