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Network neighborhood for query Sequence : TFR2_MOUSE

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TFR2_MOUSE
 
SwissProt Accessions Q9JKX3, Q920I6, Q99MQ9, Q9CPT2 Gene names Tfr2, Trfr2
Domain
Architecture
Description Transferrin receptor protein 2 (TfR2).
Rank Plots



Hits sorted by θ


TFR2_HUMAN
 
θ value 0 (rank : 1) NC score 0.997056 (rank : 2)
Query Neighborhood Hits 25 Target Neighborhood Hits 31 Shared Neighborhood Hits 16
SwissProt Accessions Q9UP52, O75422, Q9HA99, Q9NX67 Gene names TFR2
Domain
Architecture
Description Transferrin receptor protein 2 (TfR2).
TFR2_MOUSE
 
θ value 0 (rank : 2) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 25 Target Neighborhood Hits 25 Shared Neighborhood Hits 25
SwissProt Accessions Q9JKX3, Q920I6, Q99MQ9, Q9CPT2 Gene names Tfr2, Trfr2
Domain
Architecture
Description Transferrin receptor protein 2 (TfR2).
TFR1_HUMAN
 
θ value 1.08415e-162 (rank : 3) NC score 0.975125 (rank : 3)
Query Neighborhood Hits 25 Target Neighborhood Hits 22 Shared Neighborhood Hits 12
SwissProt Accessions P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21 Gene names TFRC
Domain
Architecture
Description Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).
TFR1_MOUSE
 
θ value 8.04023e-158 (rank : 4) NC score 0.973199 (rank : 4)
Query Neighborhood Hits 25 Target Neighborhood Hits 24 Shared Neighborhood Hits 12
SwissProt Accessions Q62351, Q61560 Gene names Tfrc, Trfr
Domain
Architecture
Description Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).
NALDL_MOUSE
 
θ value 5.91091e-68 (rank : 5) NC score 0.900356 (rank : 5)
Query Neighborhood Hits 25 Target Neighborhood Hits 32 Shared Neighborhood Hits 10
SwissProt Accessions Q7M758 Gene names Naaladl1, Naaladasel
Domain
Architecture

No domain graphic available

Description N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L).
FOLH1_MOUSE
 
θ value 5.00389e-67 (rank : 6) NC score 0.888547 (rank : 8)
Query Neighborhood Hits 25 Target Neighborhood Hits 20 Shared Neighborhood Hits 11
SwissProt Accessions O35409, Q9DCC2 Gene names Folh1, Mopsm, Naalad1
Domain
Architecture
Description Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen homolog).
NALD2_MOUSE
 
θ value 4.23606e-66 (rank : 7) NC score 0.890118 (rank : 7)
Query Neighborhood Hits 25 Target Neighborhood Hits 11 Shared Neighborhood Hits 10
SwissProt Accessions Q9CZR2, Q80YF8 Gene names Naalad2
Domain
Architecture

No domain graphic available

Description N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II).
NALD2_HUMAN
 
θ value 7.2256e-66 (rank : 8) NC score 0.887303 (rank : 10)
Query Neighborhood Hits 25 Target Neighborhood Hits 23 Shared Neighborhood Hits 12
SwissProt Accessions Q9Y3Q0 Gene names NAALAD2
Domain
Architecture
Description N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).
NALDL_HUMAN
 
θ value 2.10232e-65 (rank : 9) NC score 0.898158 (rank : 6)
Query Neighborhood Hits 25 Target Neighborhood Hits 20 Shared Neighborhood Hits 11
SwissProt Accessions Q9UQQ1, O43176 Gene names NAALADL1, NAALADASEL, NAALADL
Domain
Architecture
Description N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).
FOLH1_HUMAN
 
θ value 1.04338e-64 (rank : 10) NC score 0.887959 (rank : 9)
Query Neighborhood Hits 25 Target Neighborhood Hits 23 Shared Neighborhood Hits 10
SwissProt Accessions Q04609, O43748, Q16305, Q9NP15, Q9NYE2, Q9P1P8 Gene names FOLH1, FOLH, NAALAD1, PSM, PSMA
Domain
Architecture
Description Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen) (PSMA) (PSM).
NCLN_MOUSE
 
θ value 0.0113563 (rank : 11) NC score 0.152637 (rank : 12)
Query Neighborhood Hits 25 Target Neighborhood Hits 12 Shared Neighborhood Hits 7
SwissProt Accessions Q8VCM8, Q8C7Y4, Q9CX81 Gene names Ncln
Domain
Architecture

No domain graphic available

Description Nicalin precursor (Nicastrin-like protein).
NCLN_HUMAN
 
θ value 0.0148317 (rank : 12) NC score 0.157402 (rank : 11)
Query Neighborhood Hits 25 Target Neighborhood Hits 13 Shared Neighborhood Hits 7
SwissProt Accessions Q969V3, O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7, Q9BQH9, Q9BTX4, Q9NPP2 Gene names NCLN
Domain
Architecture

No domain graphic available

Description Nicalin precursor (Nicastrin-like protein).
COAA1_MOUSE
 
θ value 0.0330416 (rank : 13) NC score 0.027407 (rank : 13)
Query Neighborhood Hits 25 Target Neighborhood Hits 286 Shared Neighborhood Hits 5
SwissProt Accessions Q05306 Gene names Col10a1
Domain
Architecture
Description Collagen alpha-1(X) chain precursor.
COAA1_HUMAN
 
θ value 0.125558 (rank : 14) NC score 0.024730 (rank : 14)
Query Neighborhood Hits 25 Target Neighborhood Hits 316 Shared Neighborhood Hits 6
SwissProt Accessions Q03692 Gene names COL10A1
Domain
Architecture
Description Collagen alpha-1(X) chain precursor.
CO4A5_HUMAN
 
θ value 0.163984 (rank : 15) NC score 0.023428 (rank : 15)
Query Neighborhood Hits 25 Target Neighborhood Hits 383 Shared Neighborhood Hits 9
SwissProt Accessions P29400, Q16006, Q16126, Q6LD84 Gene names COL4A5
Domain
Architecture
Description Collagen alpha-5(IV) chain precursor.
MYO15_MOUSE
 
θ value 1.06291 (rank : 16) NC score 0.011477 (rank : 19)
Query Neighborhood Hits 25 Target Neighborhood Hits 467 Shared Neighborhood Hits 7
SwissProt Accessions Q9QZZ4, O70395, Q9QWL6 Gene names Myo15a, Myo15
Domain
Architecture
Description Myosin-15 (Myosin XV) (Unconventional myosin-15).
ATN1_HUMAN
 
θ value 1.81305 (rank : 17) NC score 0.020269 (rank : 16)
Query Neighborhood Hits 25 Target Neighborhood Hits 676 Shared Neighborhood Hits 5
SwissProt Accessions P54259, Q99495, Q99621, Q9UEK7 Gene names ATN1, DRPLA
Domain
Architecture
Description Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).
CO4A6_HUMAN
 
θ value 1.81305 (rank : 18) NC score 0.019231 (rank : 18)
Query Neighborhood Hits 25 Target Neighborhood Hits 318 Shared Neighborhood Hits 6
SwissProt Accessions Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4 Gene names COL4A6
Domain
Architecture
Description Collagen alpha-6(IV) chain precursor.
K1802_HUMAN
 
θ value 1.81305 (rank : 19) NC score 0.009259 (rank : 21)
Query Neighborhood Hits 25 Target Neighborhood Hits 1378 Shared Neighborhood Hits 6
SwissProt Accessions Q96JM3, Q6P181, Q8NC88, Q9BST0 Gene names KIAA1802, C13orf8
Domain
Architecture

No domain graphic available

Description Zinc finger protein KIAA1802.
RN133_HUMAN
 
θ value 2.36792 (rank : 20) NC score 0.019778 (rank : 17)
Query Neighborhood Hits 25 Target Neighborhood Hits 108 Shared Neighborhood Hits 3
SwissProt Accessions Q8WVZ7, Q8N7G7 Gene names RNF133
Domain
Architecture

No domain graphic available

Description RING finger protein 133.
K1802_MOUSE
 
θ value 3.0926 (rank : 21) NC score 0.007755 (rank : 22)
Query Neighborhood Hits 25 Target Neighborhood Hits 1596 Shared Neighborhood Hits 7
SwissProt Accessions Q8K327, Q3UZ85, Q6ZPI1 Gene names Kiaa1802, D8Ertd457e
Domain
Architecture

No domain graphic available

Description Zinc finger protein KIAA1802.
RFFL_MOUSE
 
θ value 5.27518 (rank : 22) NC score 0.009554 (rank : 20)
Query Neighborhood Hits 25 Target Neighborhood Hits 145 Shared Neighborhood Hits 2
SwissProt Accessions Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1 Gene names Rffl
Domain
Architecture

No domain graphic available

Description Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).
MRCKG_MOUSE
 
θ value 6.88961 (rank : 23) NC score -0.001829 (rank : 25)
Query Neighborhood Hits 25 Target Neighborhood Hits 1466 Shared Neighborhood Hits 2
SwissProt Accessions Q80UW5 Gene names Cdc42bpg
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).
RIN1_HUMAN
 
θ value 8.99809 (rank : 24) NC score 0.007121 (rank : 23)
Query Neighborhood Hits 25 Target Neighborhood Hits 52 Shared Neighborhood Hits 2
SwissProt Accessions Q13671, O15010, Q00427, Q96CC8 Gene names RIN1
Domain
Architecture
Description Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).
SEM6C_MOUSE
 
θ value 8.99809 (rank : 25) NC score 0.003262 (rank : 24)
Query Neighborhood Hits 25 Target Neighborhood Hits 352 Shared Neighborhood Hits 8
SwissProt Accessions Q9WTM3 Gene names Sema6c, Semay
Domain
Architecture
Description Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

Hits sorted by NC score


TFR2_MOUSE
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 2)
Query Neighborhood Hits 25 Target Neighborhood Hits 25 Shared Neighborhood Hits 25
SwissProt Accessions Q9JKX3, Q920I6, Q99MQ9, Q9CPT2 Gene names Tfr2, Trfr2
Domain
Architecture
Description Transferrin receptor protein 2 (TfR2).
TFR2_HUMAN
 
NC score 0.997056 (rank : 2) θ value 0 (rank : 1)
Query Neighborhood Hits 25 Target Neighborhood Hits 31 Shared Neighborhood Hits 16
SwissProt Accessions Q9UP52, O75422, Q9HA99, Q9NX67 Gene names TFR2
Domain
Architecture
Description Transferrin receptor protein 2 (TfR2).
TFR1_HUMAN
 
NC score 0.975125 (rank : 3) θ value 1.08415e-162 (rank : 3)
Query Neighborhood Hits 25 Target Neighborhood Hits 22 Shared Neighborhood Hits 12
SwissProt Accessions P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21 Gene names TFRC
Domain
Architecture
Description Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).
TFR1_MOUSE
 
NC score 0.973199 (rank : 4) θ value 8.04023e-158 (rank : 4)
Query Neighborhood Hits 25 Target Neighborhood Hits 24 Shared Neighborhood Hits 12
SwissProt Accessions Q62351, Q61560 Gene names Tfrc, Trfr
Domain
Architecture
Description Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).
NALDL_MOUSE
 
NC score 0.900356 (rank : 5) θ value 5.91091e-68 (rank : 5)
Query Neighborhood Hits 25 Target Neighborhood Hits 32 Shared Neighborhood Hits 10
SwissProt Accessions Q7M758 Gene names Naaladl1, Naaladasel
Domain
Architecture

No domain graphic available

Description N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L).
NALDL_HUMAN
 
NC score 0.898158 (rank : 6) θ value 2.10232e-65 (rank : 9)
Query Neighborhood Hits 25 Target Neighborhood Hits 20 Shared Neighborhood Hits 11
SwissProt Accessions Q9UQQ1, O43176 Gene names NAALADL1, NAALADASEL, NAALADL
Domain
Architecture
Description N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).
NALD2_MOUSE
 
NC score 0.890118 (rank : 7) θ value 4.23606e-66 (rank : 7)
Query Neighborhood Hits 25 Target Neighborhood Hits 11 Shared Neighborhood Hits 10
SwissProt Accessions Q9CZR2, Q80YF8 Gene names Naalad2
Domain
Architecture

No domain graphic available

Description N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II).
FOLH1_MOUSE
 
NC score 0.888547 (rank : 8) θ value 5.00389e-67 (rank : 6)
Query Neighborhood Hits 25 Target Neighborhood Hits 20 Shared Neighborhood Hits 11
SwissProt Accessions O35409, Q9DCC2 Gene names Folh1, Mopsm, Naalad1
Domain
Architecture
Description Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen homolog).
FOLH1_HUMAN
 
NC score 0.887959 (rank : 9) θ value 1.04338e-64 (rank : 10)
Query Neighborhood Hits 25 Target Neighborhood Hits 23 Shared Neighborhood Hits 10
SwissProt Accessions Q04609, O43748, Q16305, Q9NP15, Q9NYE2, Q9P1P8 Gene names FOLH1, FOLH, NAALAD1, PSM, PSMA
Domain
Architecture
Description Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen) (PSMA) (PSM).
NALD2_HUMAN
 
NC score 0.887303 (rank : 10) θ value 7.2256e-66 (rank : 8)
Query Neighborhood Hits 25 Target Neighborhood Hits 23 Shared Neighborhood Hits 12
SwissProt Accessions Q9Y3Q0 Gene names NAALAD2
Domain
Architecture
Description N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).
NCLN_HUMAN
 
NC score 0.157402 (rank : 11) θ value 0.0148317 (rank : 12)
Query Neighborhood Hits 25 Target Neighborhood Hits 13 Shared Neighborhood Hits 7
SwissProt Accessions Q969V3, O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7, Q9BQH9, Q9BTX4, Q9NPP2 Gene names NCLN
Domain
Architecture

No domain graphic available

Description Nicalin precursor (Nicastrin-like protein).
NCLN_MOUSE
 
NC score 0.152637 (rank : 12) θ value 0.0113563 (rank : 11)
Query Neighborhood Hits 25 Target Neighborhood Hits 12 Shared Neighborhood Hits 7
SwissProt Accessions Q8VCM8, Q8C7Y4, Q9CX81 Gene names Ncln
Domain
Architecture

No domain graphic available

Description Nicalin precursor (Nicastrin-like protein).
COAA1_MOUSE
 
NC score 0.027407 (rank : 13) θ value 0.0330416 (rank : 13)
Query Neighborhood Hits 25 Target Neighborhood Hits 286 Shared Neighborhood Hits 5
SwissProt Accessions Q05306 Gene names Col10a1
Domain
Architecture
Description Collagen alpha-1(X) chain precursor.
COAA1_HUMAN
 
NC score 0.024730 (rank : 14) θ value 0.125558 (rank : 14)
Query Neighborhood Hits 25 Target Neighborhood Hits 316 Shared Neighborhood Hits 6
SwissProt Accessions Q03692 Gene names COL10A1
Domain
Architecture
Description Collagen alpha-1(X) chain precursor.
CO4A5_HUMAN
 
NC score 0.023428 (rank : 15) θ value 0.163984 (rank : 15)
Query Neighborhood Hits 25 Target Neighborhood Hits 383 Shared Neighborhood Hits 9
SwissProt Accessions P29400, Q16006, Q16126, Q6LD84 Gene names COL4A5
Domain
Architecture
Description Collagen alpha-5(IV) chain precursor.
ATN1_HUMAN
 
NC score 0.020269 (rank : 16) θ value 1.81305 (rank : 17)
Query Neighborhood Hits 25 Target Neighborhood Hits 676 Shared Neighborhood Hits 5
SwissProt Accessions P54259, Q99495, Q99621, Q9UEK7 Gene names ATN1, DRPLA
Domain
Architecture
Description Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).
RN133_HUMAN
 
NC score 0.019778 (rank : 17) θ value 2.36792 (rank : 20)
Query Neighborhood Hits 25 Target Neighborhood Hits 108 Shared Neighborhood Hits 3
SwissProt Accessions Q8WVZ7, Q8N7G7 Gene names RNF133
Domain
Architecture

No domain graphic available

Description RING finger protein 133.
CO4A6_HUMAN
 
NC score 0.019231 (rank : 18) θ value 1.81305 (rank : 18)
Query Neighborhood Hits 25 Target Neighborhood Hits 318 Shared Neighborhood Hits 6
SwissProt Accessions Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4 Gene names COL4A6
Domain
Architecture
Description Collagen alpha-6(IV) chain precursor.
MYO15_MOUSE
 
NC score 0.011477 (rank : 19) θ value 1.06291 (rank : 16)
Query Neighborhood Hits 25 Target Neighborhood Hits 467 Shared Neighborhood Hits 7
SwissProt Accessions Q9QZZ4, O70395, Q9QWL6 Gene names Myo15a, Myo15
Domain
Architecture
Description Myosin-15 (Myosin XV) (Unconventional myosin-15).
RFFL_MOUSE
 
NC score 0.009554 (rank : 20) θ value 5.27518 (rank : 22)
Query Neighborhood Hits 25 Target Neighborhood Hits 145 Shared Neighborhood Hits 2
SwissProt Accessions Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1 Gene names Rffl
Domain
Architecture

No domain graphic available

Description Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).
K1802_HUMAN
 
NC score 0.009259 (rank : 21) θ value 1.81305 (rank : 19)
Query Neighborhood Hits 25 Target Neighborhood Hits 1378 Shared Neighborhood Hits 6
SwissProt Accessions Q96JM3, Q6P181, Q8NC88, Q9BST0 Gene names KIAA1802, C13orf8
Domain
Architecture

No domain graphic available

Description Zinc finger protein KIAA1802.
K1802_MOUSE
 
NC score 0.007755 (rank : 22) θ value 3.0926 (rank : 21)
Query Neighborhood Hits 25 Target Neighborhood Hits 1596 Shared Neighborhood Hits 7
SwissProt Accessions Q8K327, Q3UZ85, Q6ZPI1 Gene names Kiaa1802, D8Ertd457e
Domain
Architecture

No domain graphic available

Description Zinc finger protein KIAA1802.
RIN1_HUMAN
 
NC score 0.007121 (rank : 23) θ value 8.99809 (rank : 24)
Query Neighborhood Hits 25 Target Neighborhood Hits 52 Shared Neighborhood Hits 2
SwissProt Accessions Q13671, O15010, Q00427, Q96CC8 Gene names RIN1
Domain
Architecture
Description Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).
SEM6C_MOUSE
 
NC score 0.003262 (rank : 24) θ value 8.99809 (rank : 25)
Query Neighborhood Hits 25 Target Neighborhood Hits 352 Shared Neighborhood Hits 8
SwissProt Accessions Q9WTM3 Gene names Sema6c, Semay
Domain
Architecture
Description Semaphorin-6C precursor (Semaphorin Y) (Sema Y).
MRCKG_MOUSE
 
NC score -0.001829 (rank : 25) θ value 6.88961 (rank : 23)
Query Neighborhood Hits 25 Target Neighborhood Hits 1466 Shared Neighborhood Hits 2
SwissProt Accessions Q80UW5 Gene names Cdc42bpg
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).