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Network neighborhood for query Sequence : TFR1_MOUSE

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TFR1_MOUSE
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TFR1_HUMAN
θ value	0 (rank : 1)	NC score	0.998156 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21	Gene names	TFRC
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).

TFR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).

TFR2_MOUSE
θ value	8.04023e-158 (rank : 3)	NC score	0.973199 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JKX3, Q920I6, Q99MQ9, Q9CPT2	Gene names	Tfr2, Trfr2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

TFR2_HUMAN
θ value	4.87785e-155 (rank : 4)	NC score	0.973914 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UP52, O75422, Q9HA99, Q9NX67	Gene names	TFR2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

FOLH1_HUMAN
θ value	1.31987e-59 (rank : 5)	NC score	0.876438 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	Q04609, O43748, Q16305, Q9NP15, Q9NYE2, Q9P1P8	Gene names	FOLH1, FOLH, NAALAD1, PSM, PSMA
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen) (PSMA) (PSM).

NALD2_MOUSE
θ value	2.48917e-58 (rank : 6)	NC score	0.878115 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CZR2, Q80YF8	Gene names	Naalad2
Domain Architecture	No domain graphic available
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II).

FOLH1_MOUSE
θ value	9.45883e-58 (rank : 7)	NC score	0.875754 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O35409, Q9DCC2	Gene names	Folh1, Mopsm, Naalad1
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen homolog).

NALD2_HUMAN
θ value	5.19021e-56 (rank : 8)	NC score	0.873996 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q0	Gene names	NAALAD2
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).

NALDL_MOUSE
θ value	1.2784e-54 (rank : 9)	NC score	0.884212 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	Q7M758	Gene names	Naaladl1, Naaladasel
Domain Architecture	No domain graphic available
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L).

NALDL_HUMAN
θ value	1.788e-48 (rank : 10)	NC score	0.879831 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQQ1, O43176	Gene names	NAALADL1, NAALADASEL, NAALADL
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).

EDEM3_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.032683 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

GOLI_HUMAN
θ value	0.21417 (rank : 12)	NC score	0.050081 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	0.21417 (rank : 13)	NC score	0.050037 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

NCLN_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.132267 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V3, O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7, Q9BQH9, Q9BTX4, Q9NPP2	Gene names	NCLN
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

NCLN_MOUSE
θ value	1.38821 (rank : 15)	NC score	0.124724 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM8, Q8C7Y4, Q9CX81	Gene names	Ncln
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

KI67_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.012042 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	581	Shared Neighborhood Hits	2
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

NUPL_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.015524 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

KPYM_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.020560 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).

PDE4C_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.004771 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

STRN3_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.006513 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	309	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

KPYM_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.022070 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

NUPL_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.013900 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

DIAP1_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.002124 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	839	Shared Neighborhood Hits	2
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

STRN3_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.005526 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	316	Shared Neighborhood Hits	3
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

Hits sorted by NC score

TFR1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).

TFR1_HUMAN
NC score	0.998156 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21	Gene names	TFRC
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).

TFR2_HUMAN
NC score	0.973914 (rank : 3)	θ value	4.87785e-155 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UP52, O75422, Q9HA99, Q9NX67	Gene names	TFR2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

TFR2_MOUSE
NC score	0.973199 (rank : 4)	θ value	8.04023e-158 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JKX3, Q920I6, Q99MQ9, Q9CPT2	Gene names	Tfr2, Trfr2
Domain Architecture
Description	Transferrin receptor protein 2 (TfR2).

NALDL_MOUSE
NC score	0.884212 (rank : 5)	θ value	1.2784e-54 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	Q7M758	Gene names	Naaladl1, Naaladasel
Domain Architecture	No domain graphic available
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L).

NALDL_HUMAN
NC score	0.879831 (rank : 6)	θ value	1.788e-48 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQQ1, O43176	Gene names	NAALADL1, NAALADASEL, NAALADL
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).

NALD2_MOUSE
NC score	0.878115 (rank : 7)	θ value	2.48917e-58 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CZR2, Q80YF8	Gene names	Naalad2
Domain Architecture	No domain graphic available
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II).

FOLH1_HUMAN
NC score	0.876438 (rank : 8)	θ value	1.31987e-59 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	Q04609, O43748, Q16305, Q9NP15, Q9NYE2, Q9P1P8	Gene names	FOLH1, FOLH, NAALAD1, PSM, PSMA
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen) (PSMA) (PSM).

FOLH1_MOUSE
NC score	0.875754 (rank : 9)	θ value	9.45883e-58 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O35409, Q9DCC2	Gene names	Folh1, Mopsm, Naalad1
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen homolog).

NALD2_HUMAN
NC score	0.873996 (rank : 10)	θ value	5.19021e-56 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q0	Gene names	NAALAD2
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).

NCLN_HUMAN
NC score	0.132267 (rank : 11)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V3, O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7, Q9BQH9, Q9BTX4, Q9NPP2	Gene names	NCLN
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

NCLN_MOUSE
NC score	0.124724 (rank : 12)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM8, Q8C7Y4, Q9CX81	Gene names	Ncln
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

GOLI_HUMAN
NC score	0.050081 (rank : 13)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
NC score	0.050037 (rank : 14)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

EDEM3_HUMAN
NC score	0.032683 (rank : 15)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

KPYM_MOUSE
NC score	0.022070 (rank : 16)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

KPYM_HUMAN
NC score	0.020560 (rank : 17)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).

NUPL_MOUSE
NC score	0.015524 (rank : 18)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

NUPL_HUMAN
NC score	0.013900 (rank : 19)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

KI67_HUMAN
NC score	0.012042 (rank : 20)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	581	Shared Neighborhood Hits	2
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

STRN3_MOUSE
NC score	0.006513 (rank : 21)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	309	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN3_HUMAN
NC score	0.005526 (rank : 22)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	316	Shared Neighborhood Hits	3
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

PDE4C_MOUSE
NC score	0.004771 (rank : 23)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

DIAP1_MOUSE
NC score	0.002124 (rank : 24)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	839	Shared Neighborhood Hits	2
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).