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Network neighborhood for query Sequence : TRI43_HUMAN

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TRI43_HUMAN
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRI43_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	341	Target Neighborhood Hits	341	Shared Neighborhood Hits	341
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI49_HUMAN
θ value	1.02419e-128 (rank : 2)	NC score	0.968150 (rank : 2)
Query Neighborhood Hits	341	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI48_HUMAN
θ value	7.70199e-76 (rank : 3)	NC score	0.945763 (rank : 11)
Query Neighborhood Hits	341	Target Neighborhood Hits	192	Shared Neighborhood Hits	180
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI11_HUMAN
θ value	1.90147e-66 (rank : 4)	NC score	0.953826 (rank : 6)
Query Neighborhood Hits	341	Target Neighborhood Hits	316	Shared Neighborhood Hits	231
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	2.56992e-63 (rank : 5)	NC score	0.954686 (rank : 5)
Query Neighborhood Hits	341	Target Neighborhood Hits	329	Shared Neighborhood Hits	233
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI17_MOUSE
θ value	1.11734e-58 (rank : 6)	NC score	0.933214 (rank : 24)
Query Neighborhood Hits	341	Target Neighborhood Hits	620	Shared Neighborhood Hits	269
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RO52_HUMAN
θ value	2.32979e-56 (rank : 7)	NC score	0.946411 (rank : 10)
Query Neighborhood Hits	341	Target Neighborhood Hits	419	Shared Neighborhood Hits	265
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI17_HUMAN
θ value	3.0428e-56 (rank : 8)	NC score	0.957375 (rank : 3)
Query Neighborhood Hits	341	Target Neighborhood Hits	318	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI39_MOUSE
θ value	2.41096e-53 (rank : 9)	NC score	0.927555 (rank : 28)
Query Neighborhood Hits	341	Target Neighborhood Hits	691	Shared Neighborhood Hits	292
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
θ value	2.041e-52 (rank : 10)	NC score	0.925767 (rank : 30)
Query Neighborhood Hits	341	Target Neighborhood Hits	693	Shared Neighborhood Hits	293
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM4_HUMAN
θ value	3.48141e-52 (rank : 11)	NC score	0.956068 (rank : 4)
Query Neighborhood Hits	341	Target Neighborhood Hits	321	Shared Neighborhood Hits	242
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI27_HUMAN
θ value	7.75577e-52 (rank : 12)	NC score	0.937737 (rank : 19)
Query Neighborhood Hits	341	Target Neighborhood Hits	273	Shared Neighborhood Hits	218
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	1.72781e-51 (rank : 13)	NC score	0.937234 (rank : 20)
Query Neighborhood Hits	341	Target Neighborhood Hits	261	Shared Neighborhood Hits	205
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI68_HUMAN
θ value	1.11993e-50 (rank : 14)	NC score	0.947599 (rank : 9)
Query Neighborhood Hits	341	Target Neighborhood Hits	267	Shared Neighborhood Hits	219
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RO52_MOUSE
θ value	2.49495e-50 (rank : 15)	NC score	0.952736 (rank : 7)
Query Neighborhood Hits	341	Target Neighborhood Hits	360	Shared Neighborhood Hits	249
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI60_HUMAN
θ value	8.87376e-48 (rank : 16)	NC score	0.950492 (rank : 8)
Query Neighborhood Hits	341	Target Neighborhood Hits	357	Shared Neighborhood Hits	251
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI38_HUMAN
θ value	5.7518e-47 (rank : 17)	NC score	0.944083 (rank : 14)
Query Neighborhood Hits	341	Target Neighborhood Hits	373	Shared Neighborhood Hits	234
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM6_HUMAN
θ value	5.7518e-47 (rank : 18)	NC score	0.942187 (rank : 15)
Query Neighborhood Hits	341	Target Neighborhood Hits	412	Shared Neighborhood Hits	245
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI68_MOUSE
θ value	2.85459e-46 (rank : 19)	NC score	0.944331 (rank : 13)
Query Neighborhood Hits	341	Target Neighborhood Hits	356	Shared Neighborhood Hits	242
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRIM6_MOUSE
θ value	4.86918e-46 (rank : 20)	NC score	0.944554 (rank : 12)
Query Neighborhood Hits	341	Target Neighborhood Hits	451	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI34_HUMAN
θ value	1.85029e-45 (rank : 21)	NC score	0.928005 (rank : 26)
Query Neighborhood Hits	341	Target Neighborhood Hits	416	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI22_HUMAN
θ value	9.18288e-45 (rank : 22)	NC score	0.938240 (rank : 18)
Query Neighborhood Hits	341	Target Neighborhood Hits	396	Shared Neighborhood Hits	245
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI34_MOUSE
θ value	1.32601e-43 (rank : 23)	NC score	0.925244 (rank : 31)
Query Neighborhood Hits	341	Target Neighborhood Hits	332	Shared Neighborhood Hits	197
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI30_MOUSE
θ value	1.46607e-42 (rank : 24)	NC score	0.936914 (rank : 21)
Query Neighborhood Hits	341	Target Neighborhood Hits	434	Shared Neighborhood Hits	252
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI60_MOUSE
θ value	2.11701e-41 (rank : 25)	NC score	0.942030 (rank : 16)
Query Neighborhood Hits	341	Target Neighborhood Hits	240	Shared Neighborhood Hits	203
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM5_HUMAN
θ value	4.71619e-41 (rank : 26)	NC score	0.941280 (rank : 17)
Query Neighborhood Hits	341	Target Neighborhood Hits	424	Shared Neighborhood Hits	243
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM7_MOUSE
θ value	2.58786e-39 (rank : 27)	NC score	0.935251 (rank : 22)
Query Neighborhood Hits	341	Target Neighborhood Hits	358	Shared Neighborhood Hits	231
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM7_HUMAN
θ value	5.39604e-37 (rank : 28)	NC score	0.934087 (rank : 23)
Query Neighborhood Hits	341	Target Neighborhood Hits	336	Shared Neighborhood Hits	223
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI12_MOUSE
θ value	6.17384e-33 (rank : 29)	NC score	0.894846 (rank : 41)
Query Neighborhood Hits	341	Target Neighborhood Hits	387	Shared Neighborhood Hits	224
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI10_HUMAN
θ value	8.06329e-33 (rank : 30)	NC score	0.932186 (rank : 25)
Query Neighborhood Hits	341	Target Neighborhood Hits	315	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

MEFV_HUMAN
θ value	1.98606e-31 (rank : 31)	NC score	0.865544 (rank : 43)
Query Neighborhood Hits	341	Target Neighborhood Hits	431	Shared Neighborhood Hits	141
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI10_MOUSE
θ value	9.8567e-31 (rank : 32)	NC score	0.927819 (rank : 27)
Query Neighborhood Hits	341	Target Neighborhood Hits	285	Shared Neighborhood Hits	223
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI62_MOUSE
θ value	4.89182e-30 (rank : 33)	NC score	0.903605 (rank : 37)
Query Neighborhood Hits	341	Target Neighborhood Hits	478	Shared Neighborhood Hits	243
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI35_HUMAN
θ value	6.38894e-30 (rank : 34)	NC score	0.923708 (rank : 32)
Query Neighborhood Hits	341	Target Neighborhood Hits	382	Shared Neighborhood Hits	239
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	1.08979e-29 (rank : 35)	NC score	0.912195 (rank : 35)
Query Neighborhood Hits	341	Target Neighborhood Hits	465	Shared Neighborhood Hits	251
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI62_HUMAN
θ value	1.4233e-29 (rank : 36)	NC score	0.898335 (rank : 40)
Query Neighborhood Hits	341	Target Neighborhood Hits	584	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI26_HUMAN
θ value	3.50572e-28 (rank : 37)	NC score	0.926678 (rank : 29)
Query Neighborhood Hits	341	Target Neighborhood Hits	335	Shared Neighborhood Hits	237
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI31_HUMAN
θ value	1.02001e-27 (rank : 38)	NC score	0.891543 (rank : 42)
Query Neighborhood Hits	341	Target Neighborhood Hits	299	Shared Neighborhood Hits	220
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI41_HUMAN
θ value	1.73987e-27 (rank : 39)	NC score	0.914087 (rank : 34)
Query Neighborhood Hits	341	Target Neighborhood Hits	349	Shared Neighborhood Hits	206
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI15_HUMAN
θ value	4.28545e-26 (rank : 40)	NC score	0.904732 (rank : 36)
Query Neighborhood Hits	341	Target Neighborhood Hits	395	Shared Neighborhood Hits	230
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI50_MOUSE
θ value	2.77775e-25 (rank : 41)	NC score	0.903231 (rank : 38)
Query Neighborhood Hits	341	Target Neighborhood Hits	326	Shared Neighborhood Hits	240
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
θ value	2.35151e-24 (rank : 42)	NC score	0.899150 (rank : 39)
Query Neighborhood Hits	341	Target Neighborhood Hits	294	Shared Neighborhood Hits	229
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI26_MOUSE
θ value	4.43474e-23 (rank : 43)	NC score	0.921968 (rank : 33)
Query Neighborhood Hits	341	Target Neighborhood Hits	339	Shared Neighborhood Hits	240
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

BT1A1_MOUSE
θ value	3.28887e-18 (rank : 44)	NC score	0.720288 (rank : 63)
Query Neighborhood Hits	341	Target Neighborhood Hits	252	Shared Neighborhood Hits	79
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A2_HUMAN
θ value	5.60996e-18 (rank : 45)	NC score	0.723970 (rank : 60)
Query Neighborhood Hits	341	Target Neighborhood Hits	191	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT1A1_HUMAN
θ value	2.35696e-16 (rank : 46)	NC score	0.711545 (rank : 71)
Query Neighborhood Hits	341	Target Neighborhood Hits	322	Shared Neighborhood Hits	80
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A3_HUMAN
θ value	3.07829e-16 (rank : 47)	NC score	0.714332 (rank : 66)
Query Neighborhood Hits	341	Target Neighborhood Hits	195	Shared Neighborhood Hits	76
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RFPL2_HUMAN
θ value	6.85773e-16 (rank : 48)	NC score	0.811611 (rank : 50)
Query Neighborhood Hits	341	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL1_HUMAN
θ value	1.99529e-15 (rank : 49)	NC score	0.810325 (rank : 51)
Query Neighborhood Hits	341	Target Neighborhood Hits	119	Shared Neighborhood Hits	105
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL3_HUMAN
θ value	1.99529e-15 (rank : 50)	NC score	0.819182 (rank : 49)
Query Neighborhood Hits	341	Target Neighborhood Hits	134	Shared Neighborhood Hits	117
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

ERMAP_MOUSE
θ value	1.29331e-14 (rank : 51)	NC score	0.744863 (rank : 57)
Query Neighborhood Hits	341	Target Neighborhood Hits	231	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

ERMAP_HUMAN
θ value	1.68911e-14 (rank : 52)	NC score	0.781049 (rank : 54)
Query Neighborhood Hits	341	Target Neighborhood Hits	155	Shared Neighborhood Hits	78
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

BT3A3_HUMAN
θ value	4.91457e-14 (rank : 53)	NC score	0.716629 (rank : 65)
Query Neighborhood Hits	341	Target Neighborhood Hits	233	Shared Neighborhood Hits	79
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

TRI40_HUMAN
θ value	4.91457e-14 (rank : 54)	NC score	0.834385 (rank : 45)
Query Neighborhood Hits	341	Target Neighborhood Hits	279	Shared Neighborhood Hits	196
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM8_MOUSE
θ value	4.91457e-14 (rank : 55)	NC score	0.696697 (rank : 76)
Query Neighborhood Hits	341	Target Neighborhood Hits	674	Shared Neighborhood Hits	238
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BT2A1_HUMAN
θ value	1.86753e-13 (rank : 56)	NC score	0.709487 (rank : 72)
Query Neighborhood Hits	341	Target Neighborhood Hits	185	Shared Neighborhood Hits	80
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRI73_HUMAN
θ value	2.43908e-13 (rank : 57)	NC score	0.823831 (rank : 46)
Query Neighborhood Hits	341	Target Neighborhood Hits	258	Shared Neighborhood Hits	209
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM8_HUMAN
θ value	2.43908e-13 (rank : 58)	NC score	0.696787 (rank : 74)
Query Neighborhood Hits	341	Target Neighborhood Hits	650	Shared Neighborhood Hits	237
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI74_HUMAN
θ value	3.18553e-13 (rank : 59)	NC score	0.821945 (rank : 48)
Query Neighborhood Hits	341	Target Neighborhood Hits	249	Shared Neighborhood Hits	202
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI59_MOUSE
θ value	2.0648e-12 (rank : 60)	NC score	0.740316 (rank : 58)
Query Neighborhood Hits	341	Target Neighborhood Hits	292	Shared Neighborhood Hits	200
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI65_MOUSE
θ value	2.0648e-12 (rank : 61)	NC score	0.792494 (rank : 53)
Query Neighborhood Hits	341	Target Neighborhood Hits	340	Shared Neighborhood Hits	232
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_HUMAN
θ value	2.69671e-12 (rank : 62)	NC score	0.808009 (rank : 52)
Query Neighborhood Hits	341	Target Neighborhood Hits	330	Shared Neighborhood Hits	238
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

BT3A1_HUMAN
θ value	3.52202e-12 (rank : 63)	NC score	0.711684 (rank : 70)
Query Neighborhood Hits	341	Target Neighborhood Hits	229	Shared Neighborhood Hits	80
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TRI59_HUMAN
θ value	3.52202e-12 (rank : 64)	NC score	0.736711 (rank : 59)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	199
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI13_HUMAN
θ value	7.84624e-12 (rank : 65)	NC score	0.774293 (rank : 56)
Query Neighborhood Hits	341	Target Neighborhood Hits	274	Shared Neighborhood Hits	201
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

MEFV_MOUSE
θ value	1.02475e-11 (rank : 66)	NC score	0.698278 (rank : 73)
Query Neighborhood Hits	341	Target Neighborhood Hits	236	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI13_MOUSE
θ value	1.33837e-11 (rank : 67)	NC score	0.774508 (rank : 55)
Query Neighborhood Hits	341	Target Neighborhood Hits	282	Shared Neighborhood Hits	205
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI52_HUMAN
θ value	2.28291e-11 (rank : 68)	NC score	0.864084 (rank : 44)
Query Neighborhood Hits	341	Target Neighborhood Hits	213	Shared Neighborhood Hits	180
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

BTNL3_HUMAN
θ value	6.64225e-11 (rank : 69)	NC score	0.712723 (rank : 68)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BSPRY_MOUSE
θ value	7.34386e-10 (rank : 70)	NC score	0.696766 (rank : 75)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	97
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BTNL8_HUMAN
θ value	1.63604e-09 (rank : 71)	NC score	0.695549 (rank : 77)
Query Neighborhood Hits	341	Target Neighborhood Hits	177	Shared Neighborhood Hits	77
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRI25_MOUSE
θ value	2.36244e-08 (rank : 72)	NC score	0.721080 (rank : 62)
Query Neighborhood Hits	341	Target Neighborhood Hits	446	Shared Neighborhood Hits	252
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

BFAR_MOUSE
θ value	3.08544e-08 (rank : 73)	NC score	0.582471 (rank : 95)
Query Neighborhood Hits	341	Target Neighborhood Hits	232	Shared Neighborhood Hits	169
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BFAR_HUMAN
θ value	6.87365e-08 (rank : 74)	NC score	0.590237 (rank : 92)
Query Neighborhood Hits	341	Target Neighborhood Hits	222	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BSPRY_HUMAN
θ value	8.97725e-08 (rank : 75)	NC score	0.688618 (rank : 78)
Query Neighborhood Hits	341	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RNF39_HUMAN
θ value	8.97725e-08 (rank : 76)	NC score	0.822859 (rank : 47)
Query Neighborhood Hits	341	Target Neighborhood Hits	200	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI37_HUMAN
θ value	1.17247e-07 (rank : 77)	NC score	0.577888 (rank : 99)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	169
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	1.17247e-07 (rank : 78)	NC score	0.577462 (rank : 100)
Query Neighborhood Hits	341	Target Neighborhood Hits	316	Shared Neighborhood Hits	168
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

BTNL9_HUMAN
θ value	3.41135e-07 (rank : 79)	NC score	0.712770 (rank : 67)
Query Neighborhood Hits	341	Target Neighborhood Hits	125	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

TRI25_HUMAN
θ value	3.41135e-07 (rank : 80)	NC score	0.712613 (rank : 69)
Query Neighborhood Hits	341	Target Neighborhood Hits	472	Shared Neighborhood Hits	255
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI47_MOUSE
θ value	3.41135e-07 (rank : 81)	NC score	0.647844 (rank : 79)
Query Neighborhood Hits	341	Target Neighborhood Hits	295	Shared Neighborhood Hits	212
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM2_HUMAN
θ value	3.41135e-07 (rank : 82)	NC score	0.563456 (rank : 105)
Query Neighborhood Hits	341	Target Neighborhood Hits	330	Shared Neighborhood Hits	198
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

RAG1_HUMAN
θ value	4.45536e-07 (rank : 83)	NC score	0.464312 (rank : 122)
Query Neighborhood Hits	341	Target Neighborhood Hits	203	Shared Neighborhood Hits	149
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI54_HUMAN
θ value	4.45536e-07 (rank : 84)	NC score	0.578511 (rank : 97)
Query Neighborhood Hits	341	Target Neighborhood Hits	209	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM2_MOUSE
θ value	5.81887e-07 (rank : 85)	NC score	0.561731 (rank : 106)
Query Neighborhood Hits	341	Target Neighborhood Hits	331	Shared Neighborhood Hits	195
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI29_MOUSE
θ value	9.92553e-07 (rank : 86)	NC score	0.520617 (rank : 113)
Query Neighborhood Hits	341	Target Neighborhood Hits	306	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

RAG1_MOUSE
θ value	1.29631e-06 (rank : 87)	NC score	0.447658 (rank : 127)
Query Neighborhood Hits	341	Target Neighborhood Hits	189	Shared Neighborhood Hits	156
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI29_HUMAN
θ value	1.29631e-06 (rank : 88)	NC score	0.511371 (rank : 116)
Query Neighborhood Hits	341	Target Neighborhood Hits	273	Shared Neighborhood Hits	113
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

BRCA1_MOUSE
θ value	1.69304e-06 (rank : 89)	NC score	0.536159 (rank : 109)
Query Neighborhood Hits	341	Target Neighborhood Hits	436	Shared Neighborhood Hits	186
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRI54_MOUSE
θ value	2.21117e-06 (rank : 90)	NC score	0.575979 (rank : 101)
Query Neighborhood Hits	341	Target Neighborhood Hits	197	Shared Neighborhood Hits	154
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

BRCA1_HUMAN
θ value	2.88788e-06 (rank : 91)	NC score	0.547866 (rank : 107)
Query Neighborhood Hits	341	Target Neighborhood Hits	381	Shared Neighborhood Hits	193
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRIM1_HUMAN
θ value	2.88788e-06 (rank : 92)	NC score	0.582391 (rank : 96)
Query Neighborhood Hits	341	Target Neighborhood Hits	345	Shared Neighborhood Hits	220
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

SMRA3_HUMAN
θ value	3.77169e-06 (rank : 93)	NC score	0.327411 (rank : 153)
Query Neighborhood Hits	341	Target Neighborhood Hits	265	Shared Neighborhood Hits	183
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI47_HUMAN
θ value	3.77169e-06 (rank : 94)	NC score	0.633728 (rank : 81)
Query Neighborhood Hits	341	Target Neighborhood Hits	286	Shared Neighborhood Hits	212
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRIM1_MOUSE
θ value	4.92598e-06 (rank : 95)	NC score	0.578119 (rank : 98)
Query Neighborhood Hits	341	Target Neighborhood Hits	361	Shared Neighborhood Hits	222
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

SMRA3_MOUSE
θ value	6.43352e-06 (rank : 96)	NC score	0.309984 (rank : 160)
Query Neighborhood Hits	341	Target Neighborhood Hits	267	Shared Neighborhood Hits	180
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRI18_HUMAN
θ value	1.09739e-05 (rank : 97)	NC score	0.611877 (rank : 86)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	202
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI55_HUMAN
θ value	1.87187e-05 (rank : 98)	NC score	0.601412 (rank : 90)
Query Neighborhood Hits	341	Target Neighborhood Hits	292	Shared Neighborhood Hits	169
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_MOUSE
θ value	2.44474e-05 (rank : 99)	NC score	0.617790 (rank : 83)
Query Neighborhood Hits	341	Target Neighborhood Hits	240	Shared Neighborhood Hits	164
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI18_MOUSE
θ value	3.19293e-05 (rank : 100)	NC score	0.597828 (rank : 91)
Query Neighborhood Hits	341	Target Neighborhood Hits	292	Shared Neighborhood Hits	203
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

RNF8_MOUSE
θ value	4.1701e-05 (rank : 101)	NC score	0.485560 (rank : 120)
Query Neighborhood Hits	341	Target Neighborhood Hits	618	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
θ value	5.44631e-05 (rank : 102)	NC score	0.465878 (rank : 121)
Query Neighborhood Hits	341	Target Neighborhood Hits	622	Shared Neighborhood Hits	244
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI56_HUMAN
θ value	5.44631e-05 (rank : 103)	NC score	0.452001 (rank : 125)
Query Neighborhood Hits	341	Target Neighborhood Hits	339	Shared Neighborhood Hits	181
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI63_HUMAN
θ value	5.44631e-05 (rank : 104)	NC score	0.609747 (rank : 88)
Query Neighborhood Hits	341	Target Neighborhood Hits	298	Shared Neighborhood Hits	175
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM3_HUMAN
θ value	7.1131e-05 (rank : 105)	NC score	0.567706 (rank : 104)
Query Neighborhood Hits	341	Target Neighborhood Hits	357	Shared Neighborhood Hits	202
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI32_HUMAN
θ value	9.29e-05 (rank : 106)	NC score	0.619964 (rank : 82)
Query Neighborhood Hits	341	Target Neighborhood Hits	264	Shared Neighborhood Hits	168
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	9.29e-05 (rank : 107)	NC score	0.615271 (rank : 84)
Query Neighborhood Hits	341	Target Neighborhood Hits	271	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

RN168_HUMAN
θ value	0.000121331 (rank : 108)	NC score	0.537925 (rank : 108)
Query Neighborhood Hits	341	Target Neighborhood Hits	370	Shared Neighborhood Hits	193
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI56_MOUSE
θ value	0.000121331 (rank : 109)	NC score	0.450781 (rank : 126)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRIM3_MOUSE
θ value	0.000158464 (rank : 110)	NC score	0.570644 (rank : 103)
Query Neighborhood Hits	341	Target Neighborhood Hits	351	Shared Neighborhood Hits	202
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

ZN179_HUMAN
θ value	0.000158464 (rank : 111)	NC score	0.644267 (rank : 80)
Query Neighborhood Hits	341	Target Neighborhood Hits	178	Shared Neighborhood Hits	148
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

RN168_MOUSE
θ value	0.000461057 (rank : 112)	NC score	0.509817 (rank : 118)
Query Neighborhood Hits	341	Target Neighborhood Hits	440	Shared Neighborhood Hits	205
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN125_HUMAN
θ value	0.00175202 (rank : 113)	NC score	0.521037 (rank : 112)
Query Neighborhood Hits	341	Target Neighborhood Hits	230	Shared Neighborhood Hits	173
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TIF1G_HUMAN
θ value	0.00175202 (rank : 114)	NC score	0.268865 (rank : 174)
Query Neighborhood Hits	341	Target Neighborhood Hits	410	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.00175202 (rank : 115)	NC score	0.264525 (rank : 177)
Query Neighborhood Hits	341	Target Neighborhood Hits	498	Shared Neighborhood Hits	122
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PZRN3_HUMAN
θ value	0.00228821 (rank : 116)	NC score	0.236238 (rank : 191)
Query Neighborhood Hits	341	Target Neighborhood Hits	461	Shared Neighborhood Hits	177
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.00228821 (rank : 117)	NC score	0.239182 (rank : 188)
Query Neighborhood Hits	341	Target Neighborhood Hits	447	Shared Neighborhood Hits	178
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRI44_HUMAN
θ value	0.00228821 (rank : 118)	NC score	0.573301 (rank : 102)
Query Neighborhood Hits	341	Target Neighborhood Hits	393	Shared Neighborhood Hits	107
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	0.00228821 (rank : 119)	NC score	0.586759 (rank : 94)
Query Neighborhood Hits	341	Target Neighborhood Hits	327	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

RN125_MOUSE
θ value	0.00298849 (rank : 120)	NC score	0.531687 (rank : 110)
Query Neighborhood Hits	341	Target Neighborhood Hits	220	Shared Neighborhood Hits	171
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
θ value	0.00298849 (rank : 121)	NC score	0.510993 (rank : 117)
Query Neighborhood Hits	341	Target Neighborhood Hits	240	Shared Neighborhood Hits	174
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

PEX10_HUMAN
θ value	0.00390308 (rank : 122)	NC score	0.520345 (rank : 114)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	173
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRIPB_HUMAN
θ value	0.00390308 (rank : 123)	NC score	0.054321 (rank : 334)
Query Neighborhood Hits	341	Target Neighborhood Hits	1587	Shared Neighborhood Hits	134
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CHFR_HUMAN
θ value	0.00509761 (rank : 124)	NC score	0.387798 (rank : 142)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	170
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.00509761 (rank : 125)	NC score	0.381974 (rank : 143)
Query Neighborhood Hits	341	Target Neighborhood Hits	264	Shared Neighborhood Hits	173
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

LNX1_MOUSE
θ value	0.00509761 (rank : 126)	NC score	0.268521 (rank : 175)
Query Neighborhood Hits	341	Target Neighborhood Hits	377	Shared Neighborhood Hits	160
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

BARD1_MOUSE
θ value	0.00665767 (rank : 127)	NC score	0.145932 (rank : 235)
Query Neighborhood Hits	341	Target Neighborhood Hits	411	Shared Neighborhood Hits	97
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

LNX1_HUMAN
θ value	0.00665767 (rank : 128)	NC score	0.265805 (rank : 176)
Query Neighborhood Hits	341	Target Neighborhood Hits	379	Shared Neighborhood Hits	168
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

RBBP6_HUMAN
θ value	0.00665767 (rank : 129)	NC score	0.175040 (rank : 213)
Query Neighborhood Hits	341	Target Neighborhood Hits	1135	Shared Neighborhood Hits	162
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.00665767 (rank : 130)	NC score	0.190921 (rank : 207)
Query Neighborhood Hits	341	Target Neighborhood Hits	1014	Shared Neighborhood Hits	152
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RN166_MOUSE
θ value	0.00665767 (rank : 131)	NC score	0.503340 (rank : 119)
Query Neighborhood Hits	341	Target Neighborhood Hits	248	Shared Neighborhood Hits	179
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN185_HUMAN
θ value	0.00869519 (rank : 132)	NC score	0.412041 (rank : 134)
Query Neighborhood Hits	341	Target Neighborhood Hits	213	Shared Neighborhood Hits	159
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.00869519 (rank : 133)	NC score	0.411070 (rank : 135)
Query Neighborhood Hits	341	Target Neighborhood Hits	211	Shared Neighborhood Hits	159
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI14_HUMAN
θ value	0.00869519 (rank : 134)	NC score	0.717207 (rank : 64)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

GOGA4_MOUSE
θ value	0.0113563 (rank : 135)	NC score	0.067392 (rank : 298)
Query Neighborhood Hits	341	Target Neighborhood Hits	1939	Shared Neighborhood Hits	156
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CM007_MOUSE
θ value	0.0148317 (rank : 136)	NC score	0.290494 (rank : 168)
Query Neighborhood Hits	341	Target Neighborhood Hits	416	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

PCGF4_HUMAN
θ value	0.0148317 (rank : 137)	NC score	0.247091 (rank : 186)
Query Neighborhood Hits	341	Target Neighborhood Hits	161	Shared Neighborhood Hits	112
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.0148317 (rank : 138)	NC score	0.247341 (rank : 185)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	111
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

UHRF2_HUMAN
θ value	0.0148317 (rank : 139)	NC score	0.322176 (rank : 155)
Query Neighborhood Hits	341	Target Neighborhood Hits	269	Shared Neighborhood Hits	158
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	0.0148317 (rank : 140)	NC score	0.317556 (rank : 157)
Query Neighborhood Hits	341	Target Neighborhood Hits	275	Shared Neighborhood Hits	157
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BARD1_HUMAN
θ value	0.0252991 (rank : 141)	NC score	0.147277 (rank : 232)
Query Neighborhood Hits	341	Target Neighborhood Hits	427	Shared Neighborhood Hits	100
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BIRC7_HUMAN
θ value	0.0252991 (rank : 142)	NC score	0.312592 (rank : 159)
Query Neighborhood Hits	341	Target Neighborhood Hits	185	Shared Neighborhood Hits	142
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

PML_HUMAN
θ value	0.0252991 (rank : 143)	NC score	0.285524 (rank : 170)
Query Neighborhood Hits	341	Target Neighborhood Hits	248	Shared Neighborhood Hits	118
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RFWD2_MOUSE
θ value	0.0252991 (rank : 144)	NC score	0.302834 (rank : 165)
Query Neighborhood Hits	341	Target Neighborhood Hits	535	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RNF37_MOUSE
θ value	0.0252991 (rank : 145)	NC score	0.084441 (rank : 275)
Query Neighborhood Hits	341	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TRI46_HUMAN
θ value	0.0252991 (rank : 146)	NC score	0.462549 (rank : 124)
Query Neighborhood Hits	341	Target Neighborhood Hits	291	Shared Neighborhood Hits	184
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

LNX2_HUMAN
θ value	0.0330416 (rank : 147)	NC score	0.256690 (rank : 183)
Query Neighborhood Hits	341	Target Neighborhood Hits	389	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	0.0330416 (rank : 148)	NC score	0.257503 (rank : 181)
Query Neighborhood Hits	341	Target Neighborhood Hits	407	Shared Neighborhood Hits	168
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

SPRY4_MOUSE
θ value	0.0330416 (rank : 149)	NC score	0.609975 (rank : 87)
Query Neighborhood Hits	341	Target Neighborhood Hits	82	Shared Neighborhood Hits	77
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRAF6_HUMAN
θ value	0.0330416 (rank : 150)	NC score	0.355072 (rank : 149)
Query Neighborhood Hits	341	Target Neighborhood Hits	267	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	0.0330416 (rank : 151)	NC score	0.363974 (rank : 146)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	165
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

UHRF1_MOUSE
θ value	0.0330416 (rank : 152)	NC score	0.269459 (rank : 172)
Query Neighborhood Hits	341	Target Neighborhood Hits	278	Shared Neighborhood Hits	155
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CF060_HUMAN
θ value	0.0431538 (rank : 153)	NC score	0.058001 (rank : 324)
Query Neighborhood Hits	341	Target Neighborhood Hits	1270	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CM007_HUMAN
θ value	0.0431538 (rank : 154)	NC score	0.259395 (rank : 179)
Query Neighborhood Hits	341	Target Neighborhood Hits	422	Shared Neighborhood Hits	153
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

DAAM1_HUMAN
θ value	0.0431538 (rank : 155)	NC score	0.025525 (rank : 400)
Query Neighborhood Hits	341	Target Neighborhood Hits	483	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

PZRN4_HUMAN
θ value	0.0431538 (rank : 156)	NC score	0.227706 (rank : 194)
Query Neighborhood Hits	341	Target Neighborhood Hits	438	Shared Neighborhood Hits	174
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RNF5_HUMAN
θ value	0.0431538 (rank : 157)	NC score	0.394769 (rank : 136)
Query Neighborhood Hits	341	Target Neighborhood Hits	206	Shared Neighborhood Hits	155
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	0.0431538 (rank : 158)	NC score	0.393193 (rank : 137)
Query Neighborhood Hits	341	Target Neighborhood Hits	206	Shared Neighborhood Hits	154
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRAF5_MOUSE
θ value	0.0431538 (rank : 159)	NC score	0.259260 (rank : 180)
Query Neighborhood Hits	341	Target Neighborhood Hits	355	Shared Neighborhood Hits	148
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI42_HUMAN
θ value	0.0431538 (rank : 160)	NC score	0.326927 (rank : 154)
Query Neighborhood Hits	341	Target Neighborhood Hits	283	Shared Neighborhood Hits	119
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UHRF1_HUMAN
θ value	0.0431538 (rank : 161)	NC score	0.259946 (rank : 178)
Query Neighborhood Hits	341	Target Neighborhood Hits	272	Shared Neighborhood Hits	155
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ZN313_MOUSE
θ value	0.0431538 (rank : 162)	NC score	0.531014 (rank : 111)
Query Neighborhood Hits	341	Target Neighborhood Hits	273	Shared Neighborhood Hits	191
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RFWD2_HUMAN
θ value	0.0563607 (rank : 163)	NC score	0.302516 (rank : 166)
Query Neighborhood Hits	341	Target Neighborhood Hits	518	Shared Neighborhood Hits	189
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRAF5_HUMAN
θ value	0.0563607 (rank : 164)	NC score	0.238619 (rank : 189)
Query Neighborhood Hits	341	Target Neighborhood Hits	396	Shared Neighborhood Hits	162
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF7_HUMAN
θ value	0.0563607 (rank : 165)	NC score	0.204036 (rank : 198)
Query Neighborhood Hits	341	Target Neighborhood Hits	482	Shared Neighborhood Hits	163
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.0563607 (rank : 166)	NC score	0.203220 (rank : 199)
Query Neighborhood Hits	341	Target Neighborhood Hits	470	Shared Neighborhood Hits	160
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

ZN313_HUMAN
θ value	0.0563607 (rank : 167)	NC score	0.519100 (rank : 115)
Query Neighborhood Hits	341	Target Neighborhood Hits	264	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

DAAM1_MOUSE
θ value	0.0736092 (rank : 168)	NC score	0.024678 (rank : 403)
Query Neighborhood Hits	341	Target Neighborhood Hits	443	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

TRAIP_HUMAN
θ value	0.0736092 (rank : 169)	NC score	0.177625 (rank : 211)
Query Neighborhood Hits	341	Target Neighborhood Hits	780	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRI46_MOUSE
θ value	0.0736092 (rank : 170)	NC score	0.463429 (rank : 123)
Query Neighborhood Hits	341	Target Neighborhood Hits	287	Shared Neighborhood Hits	185
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRAIP_MOUSE
θ value	0.0961366 (rank : 171)	NC score	0.161489 (rank : 222)
Query Neighborhood Hits	341	Target Neighborhood Hits	745	Shared Neighborhood Hits	135
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

PCGF2_HUMAN
θ value	0.125558 (rank : 172)	NC score	0.236228 (rank : 192)
Query Neighborhood Hits	341	Target Neighborhood Hits	222	Shared Neighborhood Hits	110
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.125558 (rank : 173)	NC score	0.236308 (rank : 190)
Query Neighborhood Hits	341	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRI36_HUMAN
θ value	0.125558 (rank : 174)	NC score	0.431821 (rank : 128)
Query Neighborhood Hits	341	Target Neighborhood Hits	282	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI42_MOUSE
θ value	0.125558 (rank : 175)	NC score	0.329244 (rank : 152)
Query Neighborhood Hits	341	Target Neighborhood Hits	316	Shared Neighborhood Hits	129
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

CEP63_HUMAN
θ value	0.163984 (rank : 176)	NC score	0.046891 (rank : 360)
Query Neighborhood Hits	341	Target Neighborhood Hits	1005	Shared Neighborhood Hits	109
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

M3K1_MOUSE
θ value	0.163984 (rank : 177)	NC score	-0.001924 (rank : 434)
Query Neighborhood Hits	341	Target Neighborhood Hits	952	Shared Neighborhood Hits	21
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

PCGF6_HUMAN
θ value	0.21417 (rank : 178)	NC score	0.282422 (rank : 171)
Query Neighborhood Hits	341	Target Neighborhood Hits	178	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	0.21417 (rank : 179)	NC score	0.285929 (rank : 169)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	120
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI14_MOUSE
θ value	0.21417 (rank : 180)	NC score	0.721208 (rank : 61)
Query Neighborhood Hits	341	Target Neighborhood Hits	137	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

ZRF1_MOUSE
θ value	0.21417 (rank : 181)	NC score	0.031757 (rank : 394)
Query Neighborhood Hits	341	Target Neighborhood Hits	414	Shared Neighborhood Hits	50
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

CNOT4_HUMAN
θ value	0.279714 (rank : 182)	NC score	0.123117 (rank : 247)
Query Neighborhood Hits	341	Target Neighborhood Hits	207	Shared Neighborhood Hits	43
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	0.279714 (rank : 183)	NC score	0.117071 (rank : 252)
Query Neighborhood Hits	341	Target Neighborhood Hits	277	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

GOGA6_HUMAN
θ value	0.279714 (rank : 184)	NC score	0.048506 (rank : 356)
Query Neighborhood Hits	341	Target Neighborhood Hits	1007	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NEURL_MOUSE
θ value	0.279714 (rank : 185)	NC score	0.113665 (rank : 256)
Query Neighborhood Hits	341	Target Neighborhood Hits	106	Shared Neighborhood Hits	69
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RN141_HUMAN
θ value	0.279714 (rank : 186)	NC score	0.309042 (rank : 162)
Query Neighborhood Hits	341	Target Neighborhood Hits	199	Shared Neighborhood Hits	141
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.279714 (rank : 187)	NC score	0.308321 (rank : 164)
Query Neighborhood Hits	341	Target Neighborhood Hits	200	Shared Neighborhood Hits	142
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRI36_MOUSE
θ value	0.279714 (rank : 188)	NC score	0.423226 (rank : 131)
Query Neighborhood Hits	341	Target Neighborhood Hits	266	Shared Neighborhood Hits	169
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

ARD1_HUMAN
θ value	0.365318 (rank : 189)	NC score	0.120067 (rank : 250)
Query Neighborhood Hits	341	Target Neighborhood Hits	621	Shared Neighborhood Hits	80
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

GOGB1_HUMAN
θ value	0.365318 (rank : 190)	NC score	0.062126 (rank : 314)
Query Neighborhood Hits	341	Target Neighborhood Hits	2297	Shared Neighborhood Hits	174
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MIB2_HUMAN
θ value	0.365318 (rank : 191)	NC score	0.069764 (rank : 296)
Query Neighborhood Hits	341	Target Neighborhood Hits	438	Shared Neighborhood Hits	96
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

RN146_HUMAN
θ value	0.365318 (rank : 192)	NC score	0.339231 (rank : 150)
Query Neighborhood Hits	341	Target Neighborhood Hits	162	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.365318 (rank : 193)	NC score	0.336870 (rank : 151)
Query Neighborhood Hits	341	Target Neighborhood Hits	161	Shared Neighborhood Hits	131
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RNF37_HUMAN
θ value	0.365318 (rank : 194)	NC score	0.070564 (rank : 295)
Query Neighborhood Hits	341	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

SMC2_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.044530 (rank : 362)
Query Neighborhood Hits	341	Target Neighborhood Hits	1405	Shared Neighborhood Hits	115
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TRAF2_HUMAN
θ value	0.365318 (rank : 196)	NC score	0.196206 (rank : 203)
Query Neighborhood Hits	341	Target Neighborhood Hits	402	Shared Neighborhood Hits	136
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	0.365318 (rank : 197)	NC score	0.199271 (rank : 201)
Query Neighborhood Hits	341	Target Neighborhood Hits	394	Shared Neighborhood Hits	139
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRIM9_HUMAN
θ value	0.365318 (rank : 198)	NC score	0.430997 (rank : 129)
Query Neighborhood Hits	341	Target Neighborhood Hits	294	Shared Neighborhood Hits	172
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

BIRC2_HUMAN
θ value	0.47712 (rank : 199)	NC score	0.120922 (rank : 249)
Query Neighborhood Hits	341	Target Neighborhood Hits	142	Shared Neighborhood Hits	90
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC3_HUMAN
θ value	0.47712 (rank : 200)	NC score	0.123884 (rank : 245)
Query Neighborhood Hits	341	Target Neighborhood Hits	133	Shared Neighborhood Hits	83
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

MGRN1_HUMAN
θ value	0.47712 (rank : 201)	NC score	0.128212 (rank : 244)
Query Neighborhood Hits	341	Target Neighborhood Hits	192	Shared Neighborhood Hits	101
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	0.47712 (rank : 202)	NC score	0.130989 (rank : 243)
Query Neighborhood Hits	341	Target Neighborhood Hits	149	Shared Neighborhood Hits	98
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RING1_HUMAN
θ value	0.47712 (rank : 203)	NC score	0.419886 (rank : 132)
Query Neighborhood Hits	341	Target Neighborhood Hits	219	Shared Neighborhood Hits	156
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.47712 (rank : 204)	NC score	0.412490 (rank : 133)
Query Neighborhood Hits	341	Target Neighborhood Hits	220	Shared Neighborhood Hits	157
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	0.47712 (rank : 205)	NC score	0.391531 (rank : 139)
Query Neighborhood Hits	341	Target Neighborhood Hits	201	Shared Neighborhood Hits	152
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.47712 (rank : 206)	NC score	0.391612 (rank : 138)
Query Neighborhood Hits	341	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RKHD1_HUMAN
θ value	0.47712 (rank : 207)	NC score	0.141041 (rank : 237)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SPRY4_HUMAN
θ value	0.47712 (rank : 208)	NC score	0.586876 (rank : 93)
Query Neighborhood Hits	341	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRIM9_MOUSE
θ value	0.47712 (rank : 209)	NC score	0.427301 (rank : 130)
Query Neighborhood Hits	341	Target Neighborhood Hits	274	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

ANR26_MOUSE
θ value	0.62314 (rank : 210)	NC score	0.038680 (rank : 379)
Query Neighborhood Hits	341	Target Neighborhood Hits	1554	Shared Neighborhood Hits	126
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AZI1_MOUSE
θ value	0.62314 (rank : 211)	NC score	0.055221 (rank : 331)
Query Neighborhood Hits	341	Target Neighborhood Hits	990	Shared Neighborhood Hits	100
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BIRC2_MOUSE
θ value	0.62314 (rank : 212)	NC score	0.116383 (rank : 253)
Query Neighborhood Hits	341	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC8_HUMAN
θ value	0.62314 (rank : 213)	NC score	0.141703 (rank : 236)
Query Neighborhood Hits	341	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

DTX3_MOUSE
θ value	0.62314 (rank : 214)	NC score	0.318632 (rank : 156)
Query Neighborhood Hits	341	Target Neighborhood Hits	202	Shared Neighborhood Hits	147
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

FYCO1_HUMAN
θ value	0.62314 (rank : 215)	NC score	0.040544 (rank : 371)
Query Neighborhood Hits	341	Target Neighborhood Hits	1149	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MD1L1_MOUSE
θ value	0.62314 (rank : 216)	NC score	0.039605 (rank : 376)
Query Neighborhood Hits	341	Target Neighborhood Hits	1001	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

NEUL1_HUMAN
θ value	0.62314 (rank : 217)	NC score	0.114389 (rank : 254)
Query Neighborhood Hits	341	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

CBL_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.168536 (rank : 217)
Query Neighborhood Hits	341	Target Neighborhood Hits	353	Shared Neighborhood Hits	148
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.813845 (rank : 219)	NC score	0.165206 (rank : 219)
Query Neighborhood Hits	341	Target Neighborhood Hits	426	Shared Neighborhood Hits	151
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

DTX3_HUMAN
θ value	0.813845 (rank : 220)	NC score	0.309569 (rank : 161)
Query Neighborhood Hits	341	Target Neighborhood Hits	198	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

ENAH_MOUSE
θ value	0.813845 (rank : 221)	NC score	0.020783 (rank : 405)
Query Neighborhood Hits	341	Target Neighborhood Hits	919	Shared Neighborhood Hits	64
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GOGA4_HUMAN
θ value	0.813845 (rank : 222)	NC score	0.058220 (rank : 323)
Query Neighborhood Hits	341	Target Neighborhood Hits	2034	Shared Neighborhood Hits	161
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KIF5A_HUMAN
θ value	0.813845 (rank : 223)	NC score	0.020275 (rank : 408)
Query Neighborhood Hits	341	Target Neighborhood Hits	843	Shared Neighborhood Hits	85
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
θ value	0.813845 (rank : 224)	NC score	0.018775 (rank : 409)
Query Neighborhood Hits	341	Target Neighborhood Hits	859	Shared Neighborhood Hits	85
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

MAT1_HUMAN
θ value	0.813845 (rank : 225)	NC score	0.149151 (rank : 231)
Query Neighborhood Hits	341	Target Neighborhood Hits	179	Shared Neighborhood Hits	62
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	0.813845 (rank : 226)	NC score	0.147042 (rank : 233)
Query Neighborhood Hits	341	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

RN169_HUMAN
θ value	0.813845 (rank : 227)	NC score	0.380732 (rank : 144)
Query Neighborhood Hits	341	Target Neighborhood Hits	203	Shared Neighborhood Hits	124
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

AMFR2_HUMAN
θ value	1.06291 (rank : 228)	NC score	0.193942 (rank : 204)
Query Neighborhood Hits	341	Target Neighborhood Hits	219	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	1.06291 (rank : 229)	NC score	0.192753 (rank : 205)
Query Neighborhood Hits	341	Target Neighborhood Hits	208	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CP250_HUMAN
θ value	1.06291 (rank : 230)	NC score	0.062600 (rank : 313)
Query Neighborhood Hits	341	Target Neighborhood Hits	1805	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MIB2_MOUSE
θ value	1.06291 (rank : 231)	NC score	0.062799 (rank : 311)
Query Neighborhood Hits	341	Target Neighborhood Hits	409	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MYH10_MOUSE
θ value	1.06291 (rank : 232)	NC score	0.040431 (rank : 372)
Query Neighborhood Hits	341	Target Neighborhood Hits	1612	Shared Neighborhood Hits	142
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SYNE2_HUMAN
θ value	1.06291 (rank : 233)	NC score	0.038072 (rank : 383)
Query Neighborhood Hits	341	Target Neighborhood Hits	1323	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TNIK_HUMAN
θ value	1.06291 (rank : 234)	NC score	0.000417 (rank : 431)
Query Neighborhood Hits	341	Target Neighborhood Hits	1570	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TRAF3_MOUSE
θ value	1.06291 (rank : 235)	NC score	0.191676 (rank : 206)
Query Neighborhood Hits	341	Target Neighborhood Hits	476	Shared Neighborhood Hits	178
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

CCD91_HUMAN
θ value	1.38821 (rank : 236)	NC score	0.046926 (rank : 359)
Query Neighborhood Hits	341	Target Neighborhood Hits	868	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

MYH11_MOUSE
θ value	1.38821 (rank : 237)	NC score	0.042556 (rank : 364)
Query Neighborhood Hits	341	Target Neighborhood Hits	1777	Shared Neighborhood Hits	145
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SYCP1_MOUSE
θ value	1.38821 (rank : 238)	NC score	0.057202 (rank : 326)
Query Neighborhood Hits	341	Target Neighborhood Hits	1456	Shared Neighborhood Hits	135
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

T3JAM_HUMAN
θ value	1.38821 (rank : 239)	NC score	0.047525 (rank : 358)
Query Neighborhood Hits	341	Target Neighborhood Hits	533	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TRAF3_HUMAN
θ value	1.38821 (rank : 240)	NC score	0.183076 (rank : 209)
Query Neighborhood Hits	341	Target Neighborhood Hits	463	Shared Neighborhood Hits	167
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

ARD1_MOUSE
θ value	1.81305 (rank : 241)	NC score	0.123125 (rank : 246)
Query Neighborhood Hits	341	Target Neighborhood Hits	573	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

ASPP1_HUMAN
θ value	1.81305 (rank : 242)	NC score	0.016869 (rank : 412)
Query Neighborhood Hits	341	Target Neighborhood Hits	956	Shared Neighborhood Hits	69
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CJ118_HUMAN
θ value	1.81305 (rank : 243)	NC score	0.033037 (rank : 389)
Query Neighborhood Hits	341	Target Neighborhood Hits	937	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CT116_HUMAN
θ value	1.81305 (rank : 244)	NC score	0.043786 (rank : 363)
Query Neighborhood Hits	341	Target Neighborhood Hits	294	Shared Neighborhood Hits	47
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

RAD18_HUMAN
θ value	1.81305 (rank : 245)	NC score	0.297480 (rank : 167)
Query Neighborhood Hits	341	Target Neighborhood Hits	284	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RIR1_MOUSE
θ value	1.81305 (rank : 246)	NC score	0.014981 (rank : 413)
Query Neighborhood Hits	341	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P07742	Gene names	Rrm1
Domain Architecture
Description	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase M1 subunit) (Ribonucleotide reductase large chain).

TRIO_HUMAN
θ value	1.81305 (rank : 247)	NC score	-0.003480 (rank : 435)
Query Neighborhood Hits	341	Target Neighborhood Hits	1580	Shared Neighborhood Hits	77
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

U2AFM_HUMAN
θ value	1.81305 (rank : 248)	NC score	0.027080 (rank : 398)
Query Neighborhood Hits	341	Target Neighborhood Hits	577	Shared Neighborhood Hits	66
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

ASPP1_MOUSE
θ value	2.36792 (rank : 249)	NC score	0.013926 (rank : 415)
Query Neighborhood Hits	341	Target Neighborhood Hits	1244	Shared Neighborhood Hits	72
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BIRC3_MOUSE
θ value	2.36792 (rank : 250)	NC score	0.100301 (rank : 262)
Query Neighborhood Hits	341	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BRE1B_HUMAN
θ value	2.36792 (rank : 251)	NC score	0.112703 (rank : 257)
Query Neighborhood Hits	341	Target Neighborhood Hits	1040	Shared Neighborhood Hits	209
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	2.36792 (rank : 252)	NC score	0.114129 (rank : 255)
Query Neighborhood Hits	341	Target Neighborhood Hits	970	Shared Neighborhood Hits	206
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CENPF_HUMAN
θ value	2.36792 (rank : 253)	NC score	0.059208 (rank : 319)
Query Neighborhood Hits	341	Target Neighborhood Hits	1932	Shared Neighborhood Hits	155
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CP250_MOUSE
θ value	2.36792 (rank : 254)	NC score	0.052672 (rank : 344)
Query Neighborhood Hits	341	Target Neighborhood Hits	1583	Shared Neighborhood Hits	140
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DNL4_HUMAN
θ value	2.36792 (rank : 255)	NC score	0.013741 (rank : 416)
Query Neighborhood Hits	341	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL4_MOUSE
θ value	2.36792 (rank : 256)	NC score	0.013732 (rank : 417)
Query Neighborhood Hits	341	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

GAS8_HUMAN
θ value	2.36792 (rank : 257)	NC score	0.029355 (rank : 396)
Query Neighborhood Hits	341	Target Neighborhood Hits	819	Shared Neighborhood Hits	89
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MYH10_HUMAN
θ value	2.36792 (rank : 258)	NC score	0.039943 (rank : 373)
Query Neighborhood Hits	341	Target Neighborhood Hits	1620	Shared Neighborhood Hits	144
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH14_HUMAN
θ value	2.36792 (rank : 259)	NC score	0.028867 (rank : 397)
Query Neighborhood Hits	341	Target Neighborhood Hits	995	Shared Neighborhood Hits	103
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RN183_HUMAN
θ value	2.36792 (rank : 260)	NC score	0.364121 (rank : 145)
Query Neighborhood Hits	341	Target Neighborhood Hits	126	Shared Neighborhood Hits	104
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TFAM_HUMAN
θ value	2.36792 (rank : 261)	NC score	0.010785 (rank : 422)
Query Neighborhood Hits	341	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

CBLB_HUMAN
θ value	3.0926 (rank : 262)	NC score	0.160313 (rank : 226)
Query Neighborhood Hits	341	Target Neighborhood Hits	261	Shared Neighborhood Hits	143
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	3.0926 (rank : 263)	NC score	0.161172 (rank : 223)
Query Neighborhood Hits	341	Target Neighborhood Hits	277	Shared Neighborhood Hits	143
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	3.0926 (rank : 264)	NC score	0.160462 (rank : 225)
Query Neighborhood Hits	341	Target Neighborhood Hits	173	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CK5P2_HUMAN
θ value	3.0926 (rank : 265)	NC score	0.038931 (rank : 378)
Query Neighborhood Hits	341	Target Neighborhood Hits	1433	Shared Neighborhood Hits	119
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CTRO_MOUSE
θ value	3.0926 (rank : 266)	NC score	0.014619 (rank : 414)
Query Neighborhood Hits	341	Target Neighborhood Hits	2344	Shared Neighborhood Hits	133
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GOGA2_MOUSE
θ value	3.0926 (rank : 267)	NC score	0.039885 (rank : 374)
Query Neighborhood Hits	341	Target Neighborhood Hits	944	Shared Neighborhood Hits	107
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

HOOK3_MOUSE
θ value	3.0926 (rank : 268)	NC score	0.032084 (rank : 392)
Query Neighborhood Hits	341	Target Neighborhood Hits	1007	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

KIF5C_HUMAN
θ value	3.0926 (rank : 269)	NC score	0.025275 (rank : 401)
Query Neighborhood Hits	341	Target Neighborhood Hits	974	Shared Neighborhood Hits	100
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KR10C_HUMAN
θ value	3.0926 (rank : 270)	NC score	0.003062 (rank : 426)
Query Neighborhood Hits	341	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LIPB2_MOUSE
θ value	3.0926 (rank : 271)	NC score	0.021588 (rank : 404)
Query Neighborhood Hits	341	Target Neighborhood Hits	570	Shared Neighborhood Hits	69
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MRCKB_MOUSE
θ value	3.0926 (rank : 272)	NC score	0.013409 (rank : 418)
Query Neighborhood Hits	341	Target Neighborhood Hits	2180	Shared Neighborhood Hits	126
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH13_HUMAN
θ value	3.0926 (rank : 273)	NC score	0.029411 (rank : 395)
Query Neighborhood Hits	341	Target Neighborhood Hits	1504	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PHLB2_MOUSE
θ value	3.0926 (rank : 274)	NC score	0.045136 (rank : 361)
Query Neighborhood Hits	341	Target Neighborhood Hits	1016	Shared Neighborhood Hits	102
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLEC1_HUMAN
θ value	3.0926 (rank : 275)	NC score	0.036135 (rank : 385)
Query Neighborhood Hits	341	Target Neighborhood Hits	1326	Shared Neighborhood Hits	119
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PML_MOUSE
θ value	3.0926 (rank : 276)	NC score	0.253692 (rank : 184)
Query Neighborhood Hits	341	Target Neighborhood Hits	246	Shared Neighborhood Hits	126
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

R113B_HUMAN
θ value	3.0926 (rank : 277)	NC score	0.269386 (rank : 173)
Query Neighborhood Hits	341	Target Neighborhood Hits	165	Shared Neighborhood Hits	131
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RNF41_HUMAN
θ value	3.0926 (rank : 278)	NC score	0.390648 (rank : 141)
Query Neighborhood Hits	341	Target Neighborhood Hits	226	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	3.0926 (rank : 279)	NC score	0.390735 (rank : 140)
Query Neighborhood Hits	341	Target Neighborhood Hits	224	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SWP70_MOUSE
θ value	3.0926 (rank : 280)	NC score	0.041973 (rank : 366)
Query Neighborhood Hits	341	Target Neighborhood Hits	1097	Shared Neighborhood Hits	111
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TRHY_HUMAN
θ value	3.0926 (rank : 281)	NC score	0.049581 (rank : 354)
Query Neighborhood Hits	341	Target Neighborhood Hits	1385	Shared Neighborhood Hits	110
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

BRE1A_HUMAN
θ value	4.03905 (rank : 282)	NC score	0.094782 (rank : 267)
Query Neighborhood Hits	341	Target Neighborhood Hits	1071	Shared Neighborhood Hits	203
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	4.03905 (rank : 283)	NC score	0.092628 (rank : 268)
Query Neighborhood Hits	341	Target Neighborhood Hits	1025	Shared Neighborhood Hits	198
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CBLC_MOUSE
θ value	4.03905 (rank : 284)	NC score	0.160575 (rank : 224)
Query Neighborhood Hits	341	Target Neighborhood Hits	186	Shared Neighborhood Hits	133
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CCD42_MOUSE
θ value	4.03905 (rank : 285)	NC score	0.032768 (rank : 391)
Query Neighborhood Hits	341	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CDR2_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.024718 (rank : 402)
Query Neighborhood Hits	341	Target Neighborhood Hits	482	Shared Neighborhood Hits	70
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

GBP1_MOUSE
θ value	4.03905 (rank : 287)	NC score	0.018070 (rank : 410)
Query Neighborhood Hits	341	Target Neighborhood Hits	302	Shared Neighborhood Hits	49
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

LRSM1_MOUSE
θ value	4.03905 (rank : 288)	NC score	0.063212 (rank : 310)
Query Neighborhood Hits	341	Target Neighborhood Hits	874	Shared Neighborhood Hits	149
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

M4K4_HUMAN
θ value	4.03905 (rank : 289)	NC score	0.003280 (rank : 425)
Query Neighborhood Hits	341	Target Neighborhood Hits	1589	Shared Neighborhood Hits	83
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MKRN4_HUMAN
θ value	4.03905 (rank : 290)	NC score	0.086970 (rank : 273)
Query Neighborhood Hits	341	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MYO7A_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.006764 (rank : 423)
Query Neighborhood Hits	341	Target Neighborhood Hits	209	Shared Neighborhood Hits	21
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

RN183_MOUSE
θ value	4.03905 (rank : 292)	NC score	0.308959 (rank : 163)
Query Neighborhood Hits	341	Target Neighborhood Hits	119	Shared Neighborhood Hits	98
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TIF1B_MOUSE
θ value	4.03905 (rank : 293)	NC score	0.217089 (rank : 197)
Query Neighborhood Hits	341	Target Neighborhood Hits	276	Shared Neighborhood Hits	99
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

WDR47_MOUSE
θ value	4.03905 (rank : 294)	NC score	0.002391 (rank : 429)
Query Neighborhood Hits	341	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

ZN406_HUMAN
θ value	4.03905 (rank : 295)	NC score	-0.008240 (rank : 436)
Query Neighborhood Hits	341	Target Neighborhood Hits	794	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P243, Q3MIM5, Q6PJ01, Q75PJ7, Q75PJ9, Q86X64	Gene names	ZNF406, KIAA1485
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406 (Protein ZFAT).

ZN406_MOUSE
θ value	4.03905 (rank : 296)	NC score	-0.008602 (rank : 437)
Query Neighborhood Hits	341	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

CCD91_MOUSE
θ value	5.27518 (rank : 297)	NC score	0.037163 (rank : 384)
Query Neighborhood Hits	341	Target Neighborhood Hits	699	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD93_MOUSE
θ value	5.27518 (rank : 298)	NC score	0.020362 (rank : 407)
Query Neighborhood Hits	341	Target Neighborhood Hits	362	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CE152_HUMAN
θ value	5.27518 (rank : 299)	NC score	0.039112 (rank : 377)
Query Neighborhood Hits	341	Target Neighborhood Hits	976	Shared Neighborhood Hits	102
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

HOOK3_HUMAN
θ value	5.27518 (rank : 300)	NC score	0.032012 (rank : 393)
Query Neighborhood Hits	341	Target Neighborhood Hits	1070	Shared Neighborhood Hits	103
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

KIF5C_MOUSE
θ value	5.27518 (rank : 301)	NC score	0.026005 (rank : 399)
Query Neighborhood Hits	341	Target Neighborhood Hits	1040	Shared Neighborhood Hits	100
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KRA24_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.002681 (rank : 427)
Query Neighborhood Hits	341	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

M4K4_MOUSE
θ value	5.27518 (rank : 303)	NC score	0.003429 (rank : 424)
Query Neighborhood Hits	341	Target Neighborhood Hits	1560	Shared Neighborhood Hits	76
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

RNF17_HUMAN
θ value	5.27518 (rank : 304)	NC score	0.032801 (rank : 390)
Query Neighborhood Hits	341	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

SPAG5_MOUSE
θ value	5.27518 (rank : 305)	NC score	0.038216 (rank : 381)
Query Neighborhood Hits	341	Target Neighborhood Hits	612	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

TRAF4_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.223469 (rank : 195)
Query Neighborhood Hits	341	Target Neighborhood Hits	373	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

AZI1_HUMAN
θ value	6.88961 (rank : 307)	NC score	0.053451 (rank : 338)
Query Neighborhood Hits	341	Target Neighborhood Hits	1000	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BPAEA_MOUSE
θ value	6.88961 (rank : 308)	NC score	0.039681 (rank : 375)
Query Neighborhood Hits	341	Target Neighborhood Hits	1480	Shared Neighborhood Hits	127
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD42_HUMAN
θ value	6.88961 (rank : 309)	NC score	0.034775 (rank : 388)
Query Neighborhood Hits	341	Target Neighborhood Hits	406	Shared Neighborhood Hits	66
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CT116_MOUSE
θ value	6.88961 (rank : 310)	NC score	0.038662 (rank : 380)
Query Neighborhood Hits	341	Target Neighborhood Hits	268	Shared Neighborhood Hits	43
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CTRO_HUMAN
θ value	6.88961 (rank : 311)	NC score	0.012246 (rank : 420)
Query Neighborhood Hits	341	Target Neighborhood Hits	2092	Shared Neighborhood Hits	116
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CYLN2_MOUSE
θ value	6.88961 (rank : 312)	NC score	0.042399 (rank : 365)
Query Neighborhood Hits	341	Target Neighborhood Hits	1002	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DCE2_HUMAN
θ value	6.88961 (rank : 313)	NC score	0.002562 (rank : 428)
Query Neighborhood Hits	341	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

EP15_MOUSE
θ value	6.88961 (rank : 314)	NC score	0.038099 (rank : 382)
Query Neighborhood Hits	341	Target Neighborhood Hits	820	Shared Neighborhood Hits	88
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GCC2_MOUSE
θ value	6.88961 (rank : 315)	NC score	0.058240 (rank : 322)
Query Neighborhood Hits	341	Target Neighborhood Hits	1619	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KR105_HUMAN
θ value	6.88961 (rank : 316)	NC score	0.000276 (rank : 432)
Query Neighborhood Hits	341	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

PLSL_MOUSE
θ value	6.88961 (rank : 317)	NC score	0.001692 (rank : 430)
Query Neighborhood Hits	341	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

REST_MOUSE
θ value	6.88961 (rank : 318)	NC score	0.041105 (rank : 368)
Query Neighborhood Hits	341	Target Neighborhood Hits	1506	Shared Neighborhood Hits	124
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RIR1_HUMAN
θ value	6.88961 (rank : 319)	NC score	0.012273 (rank : 419)
Query Neighborhood Hits	341	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P23921, Q9UNN2	Gene names	RRM1, RR1
Domain Architecture
Description	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase M1 subunit) (Ribonucleotide reductase large chain).

SDCG8_HUMAN
θ value	6.88961 (rank : 320)	NC score	0.048429 (rank : 357)
Query Neighborhood Hits	341	Target Neighborhood Hits	1002	Shared Neighborhood Hits	113
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

TPR_HUMAN
θ value	6.88961 (rank : 321)	NC score	0.050632 (rank : 352)
Query Neighborhood Hits	341	Target Neighborhood Hits	1921	Shared Neighborhood Hits	145
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ANR26_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.049087 (rank : 355)
Query Neighborhood Hits	341	Target Neighborhood Hits	1614	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CCD46_HUMAN
θ value	8.99809 (rank : 323)	NC score	0.058542 (rank : 321)
Query Neighborhood Hits	341	Target Neighborhood Hits	1430	Shared Neighborhood Hits	149
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CENPE_HUMAN
θ value	8.99809 (rank : 324)	NC score	0.053467 (rank : 337)
Query Neighborhood Hits	341	Target Neighborhood Hits	2060	Shared Neighborhood Hits	155
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DUOX2_HUMAN
θ value	8.99809 (rank : 325)	NC score	-0.000336 (rank : 433)
Query Neighborhood Hits	341	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

LRSM1_HUMAN
θ value	8.99809 (rank : 326)	NC score	0.072936 (rank : 291)
Query Neighborhood Hits	341	Target Neighborhood Hits	1078	Shared Neighborhood Hits	157
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MYH14_MOUSE
θ value	8.99809 (rank : 327)	NC score	0.034817 (rank : 387)
Query Neighborhood Hits	341	Target Neighborhood Hits	1225	Shared Neighborhood Hits	123
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PHLB2_HUMAN
θ value	8.99809 (rank : 328)	NC score	0.041416 (rank : 367)
Query Neighborhood Hits	341	Target Neighborhood Hits	964	Shared Neighborhood Hits	97
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PJA1_MOUSE
θ value	8.99809 (rank : 329)	NC score	0.083120 (rank : 277)
Query Neighborhood Hits	341	Target Neighborhood Hits	145	Shared Neighborhood Hits	61
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RF1M_MOUSE
θ value	8.99809 (rank : 330)	NC score	0.011515 (rank : 421)
Query Neighborhood Hits	341	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K126	Gene names	Mtrf1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

RNF34_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.132600 (rank : 242)
Query Neighborhood Hits	341	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	8.99809 (rank : 332)	NC score	0.135462 (rank : 239)
Query Neighborhood Hits	341	Target Neighborhood Hits	160	Shared Neighborhood Hits	84
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF4_HUMAN
θ value	8.99809 (rank : 333)	NC score	0.361890 (rank : 147)
Query Neighborhood Hits	341	Target Neighborhood Hits	212	Shared Neighborhood Hits	150
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	8.99809 (rank : 334)	NC score	0.355165 (rank : 148)
Query Neighborhood Hits	341	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

SMC1A_HUMAN
θ value	8.99809 (rank : 335)	NC score	0.040869 (rank : 369)
Query Neighborhood Hits	341	Target Neighborhood Hits	1346	Shared Neighborhood Hits	120
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	8.99809 (rank : 336)	NC score	0.040602 (rank : 370)
Query Neighborhood Hits	341	Target Neighborhood Hits	1384	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SPTA1_MOUSE
θ value	8.99809 (rank : 337)	NC score	0.017246 (rank : 411)
Query Neighborhood Hits	341	Target Neighborhood Hits	675	Shared Neighborhood Hits	67
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SWP70_HUMAN
θ value	8.99809 (rank : 338)	NC score	0.035083 (rank : 386)
Query Neighborhood Hits	341	Target Neighborhood Hits	973	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TOPRS_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.197144 (rank : 202)
Query Neighborhood Hits	341	Target Neighborhood Hits	286	Shared Neighborhood Hits	126
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	8.99809 (rank : 340)	NC score	0.200112 (rank : 200)
Query Neighborhood Hits	341	Target Neighborhood Hits	263	Shared Neighborhood Hits	125
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAK2_HUMAN
θ value	8.99809 (rank : 341)	NC score	0.020711 (rank : 406)
Query Neighborhood Hits	341	Target Neighborhood Hits	476	Shared Neighborhood Hits	63
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

BIRC4_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.065283 (rank : 305)
Query Neighborhood Hits	341	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.064719 (rank : 309)
Query Neighborhood Hits	341	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BRAP_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.095353 (rank : 265)
Query Neighborhood Hits	341	Target Neighborhood Hits	560	Shared Neighborhood Hits	122
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.081938 (rank : 280)
Query Neighborhood Hits	341	Target Neighborhood Hits	409	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BT3A2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.177545 (rank : 212)
Query Neighborhood Hits	341	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTNL1_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.172045 (rank : 215)
Query Neighborhood Hits	341	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTNL2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.165972 (rank : 218)
Query Neighborhood Hits	341	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CCD41_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.052933 (rank : 342)
Query Neighborhood Hits	341	Target Neighborhood Hits	1399	Shared Neighborhood Hits	130
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD46_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.052334 (rank : 345)
Query Neighborhood Hits	341	Target Neighborhood Hits	1405	Shared Neighborhood Hits	136
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CD276_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.082628 (rank : 278)
Query Neighborhood Hits	341	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.092307 (rank : 270)
Query Neighborhood Hits	341	Target Neighborhood Hits	243	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD86_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.071328 (rank : 293)
Query Neighborhood Hits	341	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

CD86_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.068279 (rank : 297)
Query Neighborhood Hits	341	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CE290_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.050917 (rank : 351)
Query Neighborhood Hits	341	Target Neighborhood Hits	1553	Shared Neighborhood Hits	143
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

DTX3L_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.150628 (rank : 230)
Query Neighborhood Hits	341	Target Neighborhood Hits	187	Shared Neighborhood Hits	117
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DZIP3_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.050463 (rank : 353)
Query Neighborhood Hits	341	Target Neighborhood Hits	414	Shared Neighborhood Hits	100
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

FSD1L_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.077665 (rank : 286)
Query Neighborhood Hits	341	Target Neighborhood Hits	57	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.085850 (rank : 274)
Query Neighborhood Hits	341	Target Neighborhood Hits	78	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GCC1_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.055070 (rank : 332)
Query Neighborhood Hits	341	Target Neighborhood Hits	887	Shared Neighborhood Hits	108
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.051308 (rank : 350)
Query Neighborhood Hits	341	Target Neighborhood Hits	1558	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

HHLA2_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.071986 (rank : 292)
Query Neighborhood Hits	341	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

ICOSL_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.082402 (rank : 279)
Query Neighborhood Hits	341	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.065166 (rank : 306)
Query Neighborhood Hits	341	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

MIB1_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.080696 (rank : 284)
Query Neighborhood Hits	341	Target Neighborhood Hits	470	Shared Neighborhood Hits	106
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.080867 (rank : 283)
Query Neighborhood Hits	341	Target Neighborhood Hits	471	Shared Neighborhood Hits	107
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MKRN1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.062796 (rank : 312)
Query Neighborhood Hits	341	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.061737 (rank : 315)
Query Neighborhood Hits	341	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.087599 (rank : 272)
Query Neighborhood Hits	341	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.089243 (rank : 271)
Query Neighborhood Hits	341	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN3_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.073592 (rank : 290)
Query Neighborhood Hits	341	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN3_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.056986 (rank : 327)
Query Neighborhood Hits	341	Target Neighborhood Hits	137	Shared Neighborhood Hits	53
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MNAB_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.134740 (rank : 240)
Query Neighborhood Hits	341	Target Neighborhood Hits	196	Shared Neighborhood Hits	96
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.133047 (rank : 241)
Query Neighborhood Hits	341	Target Neighborhood Hits	231	Shared Neighborhood Hits	95
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MOG_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.159501 (rank : 227)
Query Neighborhood Hits	341	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.159117 (rank : 229)
Query Neighborhood Hits	341	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MYLIP_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.056077 (rank : 329)
Query Neighborhood Hits	341	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NHLC1_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.163506 (rank : 221)
Query Neighborhood Hits	341	Target Neighborhood Hits	91	Shared Neighborhood Hits	66
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.173013 (rank : 214)
Query Neighborhood Hits	341	Target Neighborhood Hits	103	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NIN_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.053700 (rank : 336)
Query Neighborhood Hits	341	Target Neighborhood Hits	1416	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PCNT_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.053358 (rank : 340)
Query Neighborhood Hits	341	Target Neighborhood Hits	1551	Shared Neighborhood Hits	130
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PDL1_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.057369 (rank : 325)
Query Neighborhood Hits	341	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.078162 (rank : 285)
Query Neighborhood Hits	341	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.065729 (rank : 300)
Query Neighborhood Hits	341	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.061474 (rank : 317)
Query Neighborhood Hits	341	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PEX2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.054995 (rank : 333)
Query Neighborhood Hits	341	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PEX2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.083153 (rank : 276)
Query Neighborhood Hits	341	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

PJA1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.103266 (rank : 261)
Query Neighborhood Hits	341	Target Neighborhood Hits	159	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

R113A_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.257108 (rank : 182)
Query Neighborhood Hits	341	Target Neighborhood Hits	177	Shared Neighborhood Hits	132
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RAD18_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.316469 (rank : 158)
Query Neighborhood Hits	341	Target Neighborhood Hits	230	Shared Neighborhood Hits	136
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RBP24_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.051496 (rank : 349)
Query Neighborhood Hits	341	Target Neighborhood Hits	1559	Shared Neighborhood Hits	150
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RC3H1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.181228 (rank : 210)
Query Neighborhood Hits	341	Target Neighborhood Hits	433	Shared Neighborhood Hits	120
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.188677 (rank : 208)
Query Neighborhood Hits	341	Target Neighborhood Hits	244	Shared Neighborhood Hits	115
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFFL_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.095038 (rank : 266)
Query Neighborhood Hits	341	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.092622 (rank : 269)
Query Neighborhood Hits	341	Target Neighborhood Hits	145	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RN103_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.073930 (rank : 288)
Query Neighborhood Hits	341	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.073915 (rank : 289)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.071198 (rank : 294)
Query Neighborhood Hits	341	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.064929 (rank : 308)
Query Neighborhood Hits	341	Target Neighborhood Hits	121	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN123_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.106018 (rank : 260)
Query Neighborhood Hits	341	Target Neighborhood Hits	175	Shared Neighborhood Hits	111
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.108298 (rank : 258)
Query Neighborhood Hits	341	Target Neighborhood Hits	174	Shared Neighborhood Hits	114
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN126_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.056579 (rank : 328)
Query Neighborhood Hits	341	Target Neighborhood Hits	126	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.065440 (rank : 302)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN152_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.159407 (rank : 228)
Query Neighborhood Hits	341	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.164895 (rank : 220)
Query Neighborhood Hits	341	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN165_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.065823 (rank : 299)
Query Neighborhood Hits	341	Target Neighborhood Hits	151	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN167_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.059801 (rank : 318)
Query Neighborhood Hits	341	Target Neighborhood Hits	157	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.065288 (rank : 304)
Query Neighborhood Hits	341	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.052751 (rank : 343)
Query Neighborhood Hits	341	Target Neighborhood Hits	147	Shared Neighborhood Hits	60
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.051573 (rank : 348)
Query Neighborhood Hits	341	Target Neighborhood Hits	164	Shared Neighborhood Hits	68
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF17_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.055835 (rank : 330)
Query Neighborhood Hits	341	Target Neighborhood Hits	147	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RNF19_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.053440 (rank : 339)
Query Neighborhood Hits	341	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.053262 (rank : 341)
Query Neighborhood Hits	341	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF24_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.052006 (rank : 347)
Query Neighborhood Hits	341	Target Neighborhood Hits	122	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.052203 (rank : 346)
Query Neighborhood Hits	341	Target Neighborhood Hits	124	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF26_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.095783 (rank : 264)
Query Neighborhood Hits	341	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF32_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.121094 (rank : 248)
Query Neighborhood Hits	341	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.106645 (rank : 259)
Query Neighborhood Hits	341	Target Neighborhood Hits	129	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

SIAH2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.065578 (rank : 301)
Query Neighborhood Hits	341	Target Neighborhood Hits	94	Shared Neighborhood Hits	58
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.065150 (rank : 307)
Query Neighborhood Hits	341	Target Neighborhood Hits	101	Shared Neighborhood Hits	57
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TIF1A_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.171135 (rank : 216)
Query Neighborhood Hits	341	Target Neighborhood Hits	327	Shared Neighborhood Hits	98
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.146105 (rank : 234)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	91
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.220598 (rank : 196)
Query Neighborhood Hits	341	Target Neighborhood Hits	312	Shared Neighborhood Hits	106
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRAF4_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.136002 (rank : 238)
Query Neighborhood Hits	341	Target Neighborhood Hits	338	Shared Neighborhood Hits	113
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRI16_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.609478 (rank : 89)
Query Neighborhood Hits	341	Target Neighborhood Hits	231	Shared Neighborhood Hits	123
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.613775 (rank : 85)
Query Neighborhood Hits	341	Target Neighborhood Hits	196	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI45_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.244595 (rank : 187)
Query Neighborhood Hits	341	Target Neighborhood Hits	155	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.228661 (rank : 193)
Query Neighborhood Hits	341	Target Neighborhood Hits	155	Shared Neighborhood Hits	98
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI66_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.077028 (rank : 287)
Query Neighborhood Hits	341	Target Neighborhood Hits	479	Shared Neighborhood Hits	76
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.081163 (rank : 282)
Query Neighborhood Hits	341	Target Neighborhood Hits	491	Shared Neighborhood Hits	78
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TTC3_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.054283 (rank : 335)
Query Neighborhood Hits	341	Target Neighborhood Hits	664	Shared Neighborhood Hits	106
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

UB7I3_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.099818 (rank : 263)
Query Neighborhood Hits	341	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.120061 (rank : 251)
Query Neighborhood Hits	341	Target Neighborhood Hits	131	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

ZN364_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.065348 (rank : 303)
Query Neighborhood Hits	341	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.058607 (rank : 320)
Query Neighborhood Hits	341	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.081256 (rank : 281)
Query Neighborhood Hits	341	Target Neighborhood Hits	151	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.061695 (rank : 316)
Query Neighborhood Hits	341	Target Neighborhood Hits	132	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

TRI43_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	341	Target Neighborhood Hits	341	Shared Neighborhood Hits	341
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI49_HUMAN
NC score	0.968150 (rank : 2)	θ value	1.02419e-128 (rank : 2)
Query Neighborhood Hits	341	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI17_HUMAN
NC score	0.957375 (rank : 3)	θ value	3.0428e-56 (rank : 8)
Query Neighborhood Hits	341	Target Neighborhood Hits	318	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM4_HUMAN
NC score	0.956068 (rank : 4)	θ value	3.48141e-52 (rank : 11)
Query Neighborhood Hits	341	Target Neighborhood Hits	321	Shared Neighborhood Hits	242
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI11_MOUSE
NC score	0.954686 (rank : 5)	θ value	2.56992e-63 (rank : 5)
Query Neighborhood Hits	341	Target Neighborhood Hits	329	Shared Neighborhood Hits	233
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.953826 (rank : 6)	θ value	1.90147e-66 (rank : 4)
Query Neighborhood Hits	341	Target Neighborhood Hits	316	Shared Neighborhood Hits	231
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

RO52_MOUSE
NC score	0.952736 (rank : 7)	θ value	2.49495e-50 (rank : 15)
Query Neighborhood Hits	341	Target Neighborhood Hits	360	Shared Neighborhood Hits	249
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI60_HUMAN
NC score	0.950492 (rank : 8)	θ value	8.87376e-48 (rank : 16)
Query Neighborhood Hits	341	Target Neighborhood Hits	357	Shared Neighborhood Hits	251
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI68_HUMAN
NC score	0.947599 (rank : 9)	θ value	1.11993e-50 (rank : 14)
Query Neighborhood Hits	341	Target Neighborhood Hits	267	Shared Neighborhood Hits	219
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RO52_HUMAN
NC score	0.946411 (rank : 10)	θ value	2.32979e-56 (rank : 7)
Query Neighborhood Hits	341	Target Neighborhood Hits	419	Shared Neighborhood Hits	265
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI48_HUMAN
NC score	0.945763 (rank : 11)	θ value	7.70199e-76 (rank : 3)
Query Neighborhood Hits	341	Target Neighborhood Hits	192	Shared Neighborhood Hits	180
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRIM6_MOUSE
NC score	0.944554 (rank : 12)	θ value	4.86918e-46 (rank : 20)
Query Neighborhood Hits	341	Target Neighborhood Hits	451	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI68_MOUSE
NC score	0.944331 (rank : 13)	θ value	2.85459e-46 (rank : 19)
Query Neighborhood Hits	341	Target Neighborhood Hits	356	Shared Neighborhood Hits	242
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI38_HUMAN
NC score	0.944083 (rank : 14)	θ value	5.7518e-47 (rank : 17)
Query Neighborhood Hits	341	Target Neighborhood Hits	373	Shared Neighborhood Hits	234
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM6_HUMAN
NC score	0.942187 (rank : 15)	θ value	5.7518e-47 (rank : 18)
Query Neighborhood Hits	341	Target Neighborhood Hits	412	Shared Neighborhood Hits	245
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI60_MOUSE
NC score	0.942030 (rank : 16)	θ value	2.11701e-41 (rank : 25)
Query Neighborhood Hits	341	Target Neighborhood Hits	240	Shared Neighborhood Hits	203
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM5_HUMAN
NC score	0.941280 (rank : 17)	θ value	4.71619e-41 (rank : 26)
Query Neighborhood Hits	341	Target Neighborhood Hits	424	Shared Neighborhood Hits	243
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI22_HUMAN
NC score	0.938240 (rank : 18)	θ value	9.18288e-45 (rank : 22)
Query Neighborhood Hits	341	Target Neighborhood Hits	396	Shared Neighborhood Hits	245
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI27_HUMAN
NC score	0.937737 (rank : 19)	θ value	7.75577e-52 (rank : 12)
Query Neighborhood Hits	341	Target Neighborhood Hits	273	Shared Neighborhood Hits	218
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.937234 (rank : 20)	θ value	1.72781e-51 (rank : 13)
Query Neighborhood Hits	341	Target Neighborhood Hits	261	Shared Neighborhood Hits	205
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI30_MOUSE
NC score	0.936914 (rank : 21)	θ value	1.46607e-42 (rank : 24)
Query Neighborhood Hits	341	Target Neighborhood Hits	434	Shared Neighborhood Hits	252
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRIM7_MOUSE
NC score	0.935251 (rank : 22)	θ value	2.58786e-39 (rank : 27)
Query Neighborhood Hits	341	Target Neighborhood Hits	358	Shared Neighborhood Hits	231
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM7_HUMAN
NC score	0.934087 (rank : 23)	θ value	5.39604e-37 (rank : 28)
Query Neighborhood Hits	341	Target Neighborhood Hits	336	Shared Neighborhood Hits	223
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI17_MOUSE
NC score	0.933214 (rank : 24)	θ value	1.11734e-58 (rank : 6)
Query Neighborhood Hits	341	Target Neighborhood Hits	620	Shared Neighborhood Hits	269
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI10_HUMAN
NC score	0.932186 (rank : 25)	θ value	8.06329e-33 (rank : 30)
Query Neighborhood Hits	341	Target Neighborhood Hits	315	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI34_HUMAN
NC score	0.928005 (rank : 26)	θ value	1.85029e-45 (rank : 21)
Query Neighborhood Hits	341	Target Neighborhood Hits	416	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI10_MOUSE
NC score	0.927819 (rank : 27)	θ value	9.8567e-31 (rank : 32)
Query Neighborhood Hits	341	Target Neighborhood Hits	285	Shared Neighborhood Hits	223
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI39_MOUSE
NC score	0.927555 (rank : 28)	θ value	2.41096e-53 (rank : 9)
Query Neighborhood Hits	341	Target Neighborhood Hits	691	Shared Neighborhood Hits	292
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI26_HUMAN
NC score	0.926678 (rank : 29)	θ value	3.50572e-28 (rank : 37)
Query Neighborhood Hits	341	Target Neighborhood Hits	335	Shared Neighborhood Hits	237
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI39_HUMAN
NC score	0.925767 (rank : 30)	θ value	2.041e-52 (rank : 10)
Query Neighborhood Hits	341	Target Neighborhood Hits	693	Shared Neighborhood Hits	293
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI34_MOUSE
NC score	0.925244 (rank : 31)	θ value	1.32601e-43 (rank : 23)
Query Neighborhood Hits	341	Target Neighborhood Hits	332	Shared Neighborhood Hits	197
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_HUMAN
NC score	0.923708 (rank : 32)	θ value	6.38894e-30 (rank : 34)
Query Neighborhood Hits	341	Target Neighborhood Hits	382	Shared Neighborhood Hits	239
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI26_MOUSE
NC score	0.921968 (rank : 33)	θ value	4.43474e-23 (rank : 43)
Query Neighborhood Hits	341	Target Neighborhood Hits	339	Shared Neighborhood Hits	240
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI41_HUMAN
NC score	0.914087 (rank : 34)	θ value	1.73987e-27 (rank : 39)
Query Neighborhood Hits	341	Target Neighborhood Hits	349	Shared Neighborhood Hits	206
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI35_MOUSE
NC score	0.912195 (rank : 35)	θ value	1.08979e-29 (rank : 35)
Query Neighborhood Hits	341	Target Neighborhood Hits	465	Shared Neighborhood Hits	251
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI15_HUMAN
NC score	0.904732 (rank : 36)	θ value	4.28545e-26 (rank : 40)
Query Neighborhood Hits	341	Target Neighborhood Hits	395	Shared Neighborhood Hits	230
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI62_MOUSE
NC score	0.903605 (rank : 37)	θ value	4.89182e-30 (rank : 33)
Query Neighborhood Hits	341	Target Neighborhood Hits	478	Shared Neighborhood Hits	243
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI50_MOUSE
NC score	0.903231 (rank : 38)	θ value	2.77775e-25 (rank : 41)
Query Neighborhood Hits	341	Target Neighborhood Hits	326	Shared Neighborhood Hits	240
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
NC score	0.899150 (rank : 39)	θ value	2.35151e-24 (rank : 42)
Query Neighborhood Hits	341	Target Neighborhood Hits	294	Shared Neighborhood Hits	229
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI62_HUMAN
NC score	0.898335 (rank : 40)	θ value	1.4233e-29 (rank : 36)
Query Neighborhood Hits	341	Target Neighborhood Hits	584	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI12_MOUSE
NC score	0.894846 (rank : 41)	θ value	6.17384e-33 (rank : 29)
Query Neighborhood Hits	341	Target Neighborhood Hits	387	Shared Neighborhood Hits	224
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI31_HUMAN
NC score	0.891543 (rank : 42)	θ value	1.02001e-27 (rank : 38)
Query Neighborhood Hits	341	Target Neighborhood Hits	299	Shared Neighborhood Hits	220
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

MEFV_HUMAN
NC score	0.865544 (rank : 43)	θ value	1.98606e-31 (rank : 31)
Query Neighborhood Hits	341	Target Neighborhood Hits	431	Shared Neighborhood Hits	141
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI52_HUMAN
NC score	0.864084 (rank : 44)	θ value	2.28291e-11 (rank : 68)
Query Neighborhood Hits	341	Target Neighborhood Hits	213	Shared Neighborhood Hits	180
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI40_HUMAN
NC score	0.834385 (rank : 45)	θ value	4.91457e-14 (rank : 54)
Query Neighborhood Hits	341	Target Neighborhood Hits	279	Shared Neighborhood Hits	196
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI73_HUMAN
NC score	0.823831 (rank : 46)	θ value	2.43908e-13 (rank : 57)
Query Neighborhood Hits	341	Target Neighborhood Hits	258	Shared Neighborhood Hits	209
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

RNF39_HUMAN
NC score	0.822859 (rank : 47)	θ value	8.97725e-08 (rank : 76)
Query Neighborhood Hits	341	Target Neighborhood Hits	200	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI74_HUMAN
NC score	0.821945 (rank : 48)	θ value	3.18553e-13 (rank : 59)
Query Neighborhood Hits	341	Target Neighborhood Hits	249	Shared Neighborhood Hits	202
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

RFPL3_HUMAN
NC score	0.819182 (rank : 49)	θ value	1.99529e-15 (rank : 50)
Query Neighborhood Hits	341	Target Neighborhood Hits	134	Shared Neighborhood Hits	117
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL2_HUMAN
NC score	0.811611 (rank : 50)	θ value	6.85773e-16 (rank : 48)
Query Neighborhood Hits	341	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL1_HUMAN
NC score	0.810325 (rank : 51)	θ value	1.99529e-15 (rank : 49)
Query Neighborhood Hits	341	Target Neighborhood Hits	119	Shared Neighborhood Hits	105
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI65_HUMAN
NC score	0.808009 (rank : 52)	θ value	2.69671e-12 (rank : 62)
Query Neighborhood Hits	341	Target Neighborhood Hits	330	Shared Neighborhood Hits	238
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
NC score	0.792494 (rank : 53)	θ value	2.0648e-12 (rank : 61)
Query Neighborhood Hits	341	Target Neighborhood Hits	340	Shared Neighborhood Hits	232
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ERMAP_HUMAN
NC score	0.781049 (rank : 54)	θ value	1.68911e-14 (rank : 52)
Query Neighborhood Hits	341	Target Neighborhood Hits	155	Shared Neighborhood Hits	78
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI13_MOUSE
NC score	0.774508 (rank : 55)	θ value	1.33837e-11 (rank : 67)
Query Neighborhood Hits	341	Target Neighborhood Hits	282	Shared Neighborhood Hits	205
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.774293 (rank : 56)	θ value	7.84624e-12 (rank : 65)
Query Neighborhood Hits	341	Target Neighborhood Hits	274	Shared Neighborhood Hits	201
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

ERMAP_MOUSE
NC score	0.744863 (rank : 57)	θ value	1.29331e-14 (rank : 51)
Query Neighborhood Hits	341	Target Neighborhood Hits	231	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRI59_MOUSE
NC score	0.740316 (rank : 58)	θ value	2.0648e-12 (rank : 60)
Query Neighborhood Hits	341	Target Neighborhood Hits	292	Shared Neighborhood Hits	200
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.736711 (rank : 59)	θ value	3.52202e-12 (rank : 64)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	199
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

BT2A2_HUMAN
NC score	0.723970 (rank : 60)	θ value	5.60996e-18 (rank : 45)
Query Neighborhood Hits	341	Target Neighborhood Hits	191	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI14_MOUSE
NC score	0.721208 (rank : 61)	θ value	0.21417 (rank : 180)
Query Neighborhood Hits	341	Target Neighborhood Hits	137	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI25_MOUSE
NC score	0.721080 (rank : 62)	θ value	2.36244e-08 (rank : 72)
Query Neighborhood Hits	341	Target Neighborhood Hits	446	Shared Neighborhood Hits	252
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

BT1A1_MOUSE
NC score	0.720288 (rank : 63)	θ value	3.28887e-18 (rank : 44)
Query Neighborhood Hits	341	Target Neighborhood Hits	252	Shared Neighborhood Hits	79
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

TRI14_HUMAN
NC score	0.717207 (rank : 64)	θ value	0.00869519 (rank : 134)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

BT3A3_HUMAN
NC score	0.716629 (rank : 65)	θ value	4.91457e-14 (rank : 53)
Query Neighborhood Hits	341	Target Neighborhood Hits	233	Shared Neighborhood Hits	79
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT2A3_HUMAN
NC score	0.714332 (rank : 66)	θ value	3.07829e-16 (rank : 47)
Query Neighborhood Hits	341	Target Neighborhood Hits	195	Shared Neighborhood Hits	76
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL9_HUMAN
NC score	0.712770 (rank : 67)	θ value	3.41135e-07 (rank : 79)
Query Neighborhood Hits	341	Target Neighborhood Hits	125	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BTNL3_HUMAN
NC score	0.712723 (rank : 68)	θ value	6.64225e-11 (rank : 69)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI25_HUMAN
NC score	0.712613 (rank : 69)	θ value	3.41135e-07 (rank : 80)
Query Neighborhood Hits	341	Target Neighborhood Hits	472	Shared Neighborhood Hits	255
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

BT3A1_HUMAN
NC score	0.711684 (rank : 70)	θ value	3.52202e-12 (rank : 63)
Query Neighborhood Hits	341	Target Neighborhood Hits	229	Shared Neighborhood Hits	80
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT1A1_HUMAN
NC score	0.711545 (rank : 71)	θ value	2.35696e-16 (rank : 46)
Query Neighborhood Hits	341	Target Neighborhood Hits	322	Shared Neighborhood Hits	80
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
NC score	0.709487 (rank : 72)	θ value	1.86753e-13 (rank : 56)
Query Neighborhood Hits	341	Target Neighborhood Hits	185	Shared Neighborhood Hits	80
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

MEFV_MOUSE
NC score	0.698278 (rank : 73)	θ value	1.02475e-11 (rank : 66)
Query Neighborhood Hits	341	Target Neighborhood Hits	236	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRIM8_HUMAN
NC score	0.696787 (rank : 74)	θ value	2.43908e-13 (rank : 58)
Query Neighborhood Hits	341	Target Neighborhood Hits	650	Shared Neighborhood Hits	237
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BSPRY_MOUSE
NC score	0.696766 (rank : 75)	θ value	7.34386e-10 (rank : 70)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	97
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRIM8_MOUSE
NC score	0.696697 (rank : 76)	θ value	4.91457e-14 (rank : 55)
Query Neighborhood Hits	341	Target Neighborhood Hits	674	Shared Neighborhood Hits	238
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BTNL8_HUMAN
NC score	0.695549 (rank : 77)	θ value	1.63604e-09 (rank : 71)
Query Neighborhood Hits	341	Target Neighborhood Hits	177	Shared Neighborhood Hits	77
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BSPRY_HUMAN
NC score	0.688618 (rank : 78)	θ value	8.97725e-08 (rank : 75)
Query Neighborhood Hits	341	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI47_MOUSE
NC score	0.647844 (rank : 79)	θ value	3.41135e-07 (rank : 81)
Query Neighborhood Hits	341	Target Neighborhood Hits	295	Shared Neighborhood Hits	212
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

ZN179_HUMAN
NC score	0.644267 (rank : 80)	θ value	0.000158464 (rank : 111)
Query Neighborhood Hits	341	Target Neighborhood Hits	178	Shared Neighborhood Hits	148
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI47_HUMAN
NC score	0.633728 (rank : 81)	θ value	3.77169e-06 (rank : 94)
Query Neighborhood Hits	341	Target Neighborhood Hits	286	Shared Neighborhood Hits	212
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI32_HUMAN
NC score	0.619964 (rank : 82)	θ value	9.29e-05 (rank : 106)
Query Neighborhood Hits	341	Target Neighborhood Hits	264	Shared Neighborhood Hits	168
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI63_MOUSE
NC score	0.617790 (rank : 83)	θ value	2.44474e-05 (rank : 99)
Query Neighborhood Hits	341	Target Neighborhood Hits	240	Shared Neighborhood Hits	164
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI32_MOUSE
NC score	0.615271 (rank : 84)	θ value	9.29e-05 (rank : 107)
Query Neighborhood Hits	341	Target Neighborhood Hits	271	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI16_MOUSE
NC score	0.613775 (rank : 85)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	341	Target Neighborhood Hits	196	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI18_HUMAN
NC score	0.611877 (rank : 86)	θ value	1.09739e-05 (rank : 97)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	202
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

SPRY4_MOUSE
NC score	0.609975 (rank : 87)	θ value	0.0330416 (rank : 149)
Query Neighborhood Hits	341	Target Neighborhood Hits	82	Shared Neighborhood Hits	77
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI63_HUMAN
NC score	0.609747 (rank : 88)	θ value	5.44631e-05 (rank : 104)
Query Neighborhood Hits	341	Target Neighborhood Hits	298	Shared Neighborhood Hits	175
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI16_HUMAN
NC score	0.609478 (rank : 89)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	341	Target Neighborhood Hits	231	Shared Neighborhood Hits	123
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI55_HUMAN
NC score	0.601412 (rank : 90)	θ value	1.87187e-05 (rank : 98)
Query Neighborhood Hits	341	Target Neighborhood Hits	292	Shared Neighborhood Hits	169
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI18_MOUSE
NC score	0.597828 (rank : 91)	θ value	3.19293e-05 (rank : 100)
Query Neighborhood Hits	341	Target Neighborhood Hits	292	Shared Neighborhood Hits	203
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

BFAR_HUMAN
NC score	0.590237 (rank : 92)	θ value	6.87365e-08 (rank : 74)
Query Neighborhood Hits	341	Target Neighborhood Hits	222	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

SPRY4_HUMAN
NC score	0.586876 (rank : 93)	θ value	0.47712 (rank : 208)
Query Neighborhood Hits	341	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI44_MOUSE
NC score	0.586759 (rank : 94)	θ value	0.00228821 (rank : 119)
Query Neighborhood Hits	341	Target Neighborhood Hits	327	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

BFAR_MOUSE
NC score	0.582471 (rank : 95)	θ value	3.08544e-08 (rank : 73)
Query Neighborhood Hits	341	Target Neighborhood Hits	232	Shared Neighborhood Hits	169
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRIM1_HUMAN
NC score	0.582391 (rank : 96)	θ value	2.88788e-06 (rank : 92)
Query Neighborhood Hits	341	Target Neighborhood Hits	345	Shared Neighborhood Hits	220
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI54_HUMAN
NC score	0.578511 (rank : 97)	θ value	4.45536e-07 (rank : 84)
Query Neighborhood Hits	341	Target Neighborhood Hits	209	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM1_MOUSE
NC score	0.578119 (rank : 98)	θ value	4.92598e-06 (rank : 95)
Query Neighborhood Hits	341	Target Neighborhood Hits	361	Shared Neighborhood Hits	222
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI37_HUMAN
NC score	0.577888 (rank : 99)	θ value	1.17247e-07 (rank : 77)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	169
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.577462 (rank : 100)	θ value	1.17247e-07 (rank : 78)
Query Neighborhood Hits	341	Target Neighborhood Hits	316	Shared Neighborhood Hits	168
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI54_MOUSE
NC score	0.575979 (rank : 101)	θ value	2.21117e-06 (rank : 90)
Query Neighborhood Hits	341	Target Neighborhood Hits	197	Shared Neighborhood Hits	154
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI44_HUMAN
NC score	0.573301 (rank : 102)	θ value	0.00228821 (rank : 118)
Query Neighborhood Hits	341	Target Neighborhood Hits	393	Shared Neighborhood Hits	107
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRIM3_MOUSE
NC score	0.570644 (rank : 103)	θ value	0.000158464 (rank : 110)
Query Neighborhood Hits	341	Target Neighborhood Hits	351	Shared Neighborhood Hits	202
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.567706 (rank : 104)	θ value	7.1131e-05 (rank : 105)
Query Neighborhood Hits	341	Target Neighborhood Hits	357	Shared Neighborhood Hits	202
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_HUMAN
NC score	0.563456 (rank : 105)	θ value	3.41135e-07 (rank : 82)
Query Neighborhood Hits	341	Target Neighborhood Hits	330	Shared Neighborhood Hits	198
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.561731 (rank : 106)	θ value	5.81887e-07 (rank : 85)
Query Neighborhood Hits	341	Target Neighborhood Hits	331	Shared Neighborhood Hits	195
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

BRCA1_HUMAN
NC score	0.547866 (rank : 107)	θ value	2.88788e-06 (rank : 91)
Query Neighborhood Hits	341	Target Neighborhood Hits	381	Shared Neighborhood Hits	193
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RN168_HUMAN
NC score	0.537925 (rank : 108)	θ value	0.000121331 (rank : 108)
Query Neighborhood Hits	341	Target Neighborhood Hits	370	Shared Neighborhood Hits	193
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

BRCA1_MOUSE
NC score	0.536159 (rank : 109)	θ value	1.69304e-06 (rank : 89)
Query Neighborhood Hits	341	Target Neighborhood Hits	436	Shared Neighborhood Hits	186
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RN125_MOUSE
NC score	0.531687 (rank : 110)	θ value	0.00298849 (rank : 120)
Query Neighborhood Hits	341	Target Neighborhood Hits	220	Shared Neighborhood Hits	171
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

ZN313_MOUSE
NC score	0.531014 (rank : 111)	θ value	0.0431538 (rank : 162)
Query Neighborhood Hits	341	Target Neighborhood Hits	273	Shared Neighborhood Hits	191
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RN125_HUMAN
NC score	0.521037 (rank : 112)	θ value	0.00175202 (rank : 113)
Query Neighborhood Hits	341	Target Neighborhood Hits	230	Shared Neighborhood Hits	173
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI29_MOUSE
NC score	0.520617 (rank : 113)	θ value	9.92553e-07 (rank : 86)
Query Neighborhood Hits	341	Target Neighborhood Hits	306	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

PEX10_HUMAN
NC score	0.520345 (rank : 114)	θ value	0.00390308 (rank : 122)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	173
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ZN313_HUMAN
NC score	0.519100 (rank : 115)	θ value	0.0563607 (rank : 167)
Query Neighborhood Hits	341	Target Neighborhood Hits	264	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI29_HUMAN
NC score	0.511371 (rank : 116)	θ value	1.29631e-06 (rank : 88)
Query Neighborhood Hits	341	Target Neighborhood Hits	273	Shared Neighborhood Hits	113
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

RN166_HUMAN
NC score	0.510993 (rank : 117)	θ value	0.00298849 (rank : 121)
Query Neighborhood Hits	341	Target Neighborhood Hits	240	Shared Neighborhood Hits	174
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_MOUSE
NC score	0.509817 (rank : 118)	θ value	0.000461057 (rank : 112)
Query Neighborhood Hits	341	Target Neighborhood Hits	440	Shared Neighborhood Hits	205
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN166_MOUSE
NC score	0.503340 (rank : 119)	θ value	0.00665767 (rank : 131)
Query Neighborhood Hits	341	Target Neighborhood Hits	248	Shared Neighborhood Hits	179
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF8_MOUSE
NC score	0.485560 (rank : 120)	θ value	4.1701e-05 (rank : 101)
Query Neighborhood Hits	341	Target Neighborhood Hits	618	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
NC score	0.465878 (rank : 121)	θ value	5.44631e-05 (rank : 102)
Query Neighborhood Hits	341	Target Neighborhood Hits	622	Shared Neighborhood Hits	244
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RAG1_HUMAN
NC score	0.464312 (rank : 122)	θ value	4.45536e-07 (rank : 83)
Query Neighborhood Hits	341	Target Neighborhood Hits	203	Shared Neighborhood Hits	149
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI46_MOUSE
NC score	0.463429 (rank : 123)	θ value	0.0736092 (rank : 170)
Query Neighborhood Hits	341	Target Neighborhood Hits	287	Shared Neighborhood Hits	185
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.462549 (rank : 124)	θ value	0.0252991 (rank : 146)
Query Neighborhood Hits	341	Target Neighborhood Hits	291	Shared Neighborhood Hits	184
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI56_HUMAN
NC score	0.452001 (rank : 125)	θ value	5.44631e-05 (rank : 103)
Query Neighborhood Hits	341	Target Neighborhood Hits	339	Shared Neighborhood Hits	181
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
NC score	0.450781 (rank : 126)	θ value	0.000121331 (rank : 109)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

RAG1_MOUSE
NC score	0.447658 (rank : 127)	θ value	1.29631e-06 (rank : 87)
Query Neighborhood Hits	341	Target Neighborhood Hits	189	Shared Neighborhood Hits	156
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI36_HUMAN
NC score	0.431821 (rank : 128)	θ value	0.125558 (rank : 174)
Query Neighborhood Hits	341	Target Neighborhood Hits	282	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM9_HUMAN
NC score	0.430997 (rank : 129)	θ value	0.365318 (rank : 198)
Query Neighborhood Hits	341	Target Neighborhood Hits	294	Shared Neighborhood Hits	172
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.427301 (rank : 130)	θ value	0.47712 (rank : 209)
Query Neighborhood Hits	341	Target Neighborhood Hits	274	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI36_MOUSE
NC score	0.423226 (rank : 131)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	341	Target Neighborhood Hits	266	Shared Neighborhood Hits	169
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

RING1_HUMAN
NC score	0.419886 (rank : 132)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	341	Target Neighborhood Hits	219	Shared Neighborhood Hits	156
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.412490 (rank : 133)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	341	Target Neighborhood Hits	220	Shared Neighborhood Hits	157
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RN185_HUMAN
NC score	0.412041 (rank : 134)	θ value	0.00869519 (rank : 132)
Query Neighborhood Hits	341	Target Neighborhood Hits	213	Shared Neighborhood Hits	159
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.411070 (rank : 135)	θ value	0.00869519 (rank : 133)
Query Neighborhood Hits	341	Target Neighborhood Hits	211	Shared Neighborhood Hits	159
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF5_HUMAN
NC score	0.394769 (rank : 136)	θ value	0.0431538 (rank : 157)
Query Neighborhood Hits	341	Target Neighborhood Hits	206	Shared Neighborhood Hits	155
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.393193 (rank : 137)	θ value	0.0431538 (rank : 158)
Query Neighborhood Hits	341	Target Neighborhood Hits	206	Shared Neighborhood Hits	154
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RING2_MOUSE
NC score	0.391612 (rank : 138)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	341	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.391531 (rank : 139)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	341	Target Neighborhood Hits	201	Shared Neighborhood Hits	152
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RNF41_MOUSE
NC score	0.390735 (rank : 140)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	341	Target Neighborhood Hits	224	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.390648 (rank : 141)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	341	Target Neighborhood Hits	226	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

CHFR_HUMAN
NC score	0.387798 (rank : 142)	θ value	0.00509761 (rank : 124)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	170
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
NC score	0.381974 (rank : 143)	θ value	0.00509761 (rank : 125)
Query Neighborhood Hits	341	Target Neighborhood Hits	264	Shared Neighborhood Hits	173
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN169_HUMAN
NC score	0.380732 (rank : 144)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	341	Target Neighborhood Hits	203	Shared Neighborhood Hits	124
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
NC score	0.364121 (rank : 145)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	341	Target Neighborhood Hits	126	Shared Neighborhood Hits	104
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRAF6_MOUSE
NC score	0.363974 (rank : 146)	θ value	0.0330416 (rank : 151)
Query Neighborhood Hits	341	Target Neighborhood Hits	255	Shared Neighborhood Hits	165
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

RNF4_HUMAN
NC score	0.361890 (rank : 147)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	341	Target Neighborhood Hits	212	Shared Neighborhood Hits	150
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.355165 (rank : 148)	θ value	8.99809 (rank : 334)
Query Neighborhood Hits	341	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRAF6_HUMAN
NC score	0.355072 (rank : 149)	θ value	0.0330416 (rank : 150)
Query Neighborhood Hits	341	Target Neighborhood Hits	267	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RN146_HUMAN
NC score	0.339231 (rank : 150)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	341	Target Neighborhood Hits	162	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.336870 (rank : 151)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	341	Target Neighborhood Hits	161	Shared Neighborhood Hits	131
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI42_MOUSE
NC score	0.329244 (rank : 152)	θ value	0.125558 (rank : 175)
Query Neighborhood Hits	341	Target Neighborhood Hits	316	Shared Neighborhood Hits	129
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

SMRA3_HUMAN
NC score	0.327411 (rank : 153)	θ value	3.77169e-06 (rank : 93)
Query Neighborhood Hits	341	Target Neighborhood Hits	265	Shared Neighborhood Hits	183
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI42_HUMAN
NC score	0.326927 (rank : 154)	θ value	0.0431538 (rank : 160)
Query Neighborhood Hits	341	Target Neighborhood Hits	283	Shared Neighborhood Hits	119
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UHRF2_HUMAN
NC score	0.322176 (rank : 155)	θ value	0.0148317 (rank : 139)
Query Neighborhood Hits	341	Target Neighborhood Hits	269	Shared Neighborhood Hits	158
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

DTX3_MOUSE
NC score	0.318632 (rank : 156)	θ value	0.62314 (rank : 214)
Query Neighborhood Hits	341	Target Neighborhood Hits	202	Shared Neighborhood Hits	147
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

UHRF2_MOUSE
NC score	0.317556 (rank : 157)	θ value	0.0148317 (rank : 140)
Query Neighborhood Hits	341	Target Neighborhood Hits	275	Shared Neighborhood Hits	157
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

RAD18_MOUSE
NC score	0.316469 (rank : 158)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	341	Target Neighborhood Hits	230	Shared Neighborhood Hits	136
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

BIRC7_HUMAN
NC score	0.312592 (rank : 159)	θ value	0.0252991 (rank : 142)
Query Neighborhood Hits	341	Target Neighborhood Hits	185	Shared Neighborhood Hits	142
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

SMRA3_MOUSE
NC score	0.309984 (rank : 160)	θ value	6.43352e-06 (rank : 96)
Query Neighborhood Hits	341	Target Neighborhood Hits	267	Shared Neighborhood Hits	180
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

DTX3_HUMAN
NC score	0.309569 (rank : 161)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	341	Target Neighborhood Hits	198	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RN141_HUMAN
NC score	0.309042 (rank : 162)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	341	Target Neighborhood Hits	199	Shared Neighborhood Hits	141
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN183_MOUSE
NC score	0.308959 (rank : 163)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	341	Target Neighborhood Hits	119	Shared Neighborhood Hits	98
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN141_MOUSE
NC score	0.308321 (rank : 164)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	341	Target Neighborhood Hits	200	Shared Neighborhood Hits	142
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RFWD2_MOUSE
NC score	0.302834 (rank : 165)	θ value	0.0252991 (rank : 144)
Query Neighborhood Hits	341	Target Neighborhood Hits	535	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.302516 (rank : 166)	θ value	0.0563607 (rank : 163)
Query Neighborhood Hits	341	Target Neighborhood Hits	518	Shared Neighborhood Hits	189
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RAD18_HUMAN
NC score	0.297480 (rank : 167)	θ value	1.81305 (rank : 245)
Query Neighborhood Hits	341	Target Neighborhood Hits	284	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

CM007_MOUSE
NC score	0.290494 (rank : 168)	θ value	0.0148317 (rank : 136)
Query Neighborhood Hits	341	Target Neighborhood Hits	416	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

PCGF6_MOUSE
NC score	0.285929 (rank : 169)	θ value	0.21417 (rank : 179)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	120
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PML_HUMAN
NC score	0.285524 (rank : 170)	θ value	0.0252991 (rank : 143)
Query Neighborhood Hits	341	Target Neighborhood Hits	248	Shared Neighborhood Hits	118
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PCGF6_HUMAN
NC score	0.282422 (rank : 171)	θ value	0.21417 (rank : 178)
Query Neighborhood Hits	341	Target Neighborhood Hits	178	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

UHRF1_MOUSE
NC score	0.269459 (rank : 172)	θ value	0.0330416 (rank : 152)
Query Neighborhood Hits	341	Target Neighborhood Hits	278	Shared Neighborhood Hits	155
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

R113B_HUMAN
NC score	0.269386 (rank : 173)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	341	Target Neighborhood Hits	165	Shared Neighborhood Hits	131
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TIF1G_HUMAN
NC score	0.268865 (rank : 174)	θ value	0.00175202 (rank : 114)
Query Neighborhood Hits	341	Target Neighborhood Hits	410	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

LNX1_MOUSE
NC score	0.268521 (rank : 175)	θ value	0.00509761 (rank : 126)
Query Neighborhood Hits	341	Target Neighborhood Hits	377	Shared Neighborhood Hits	160
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.265805 (rank : 176)	θ value	0.00665767 (rank : 128)
Query Neighborhood Hits	341	Target Neighborhood Hits	379	Shared Neighborhood Hits	168
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TIF1G_MOUSE
NC score	0.264525 (rank : 177)	θ value	0.00175202 (rank : 115)
Query Neighborhood Hits	341	Target Neighborhood Hits	498	Shared Neighborhood Hits	122
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

UHRF1_HUMAN
NC score	0.259946 (rank : 178)	θ value	0.0431538 (rank : 161)
Query Neighborhood Hits	341	Target Neighborhood Hits	272	Shared Neighborhood Hits	155
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CM007_HUMAN
NC score	0.259395 (rank : 179)	θ value	0.0431538 (rank : 154)
Query Neighborhood Hits	341	Target Neighborhood Hits	422	Shared Neighborhood Hits	153
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRAF5_MOUSE
NC score	0.259260 (rank : 180)	θ value	0.0431538 (rank : 159)
Query Neighborhood Hits	341	Target Neighborhood Hits	355	Shared Neighborhood Hits	148
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

LNX2_MOUSE
NC score	0.257503 (rank : 181)	θ value	0.0330416 (rank : 148)
Query Neighborhood Hits	341	Target Neighborhood Hits	407	Shared Neighborhood Hits	168
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

R113A_HUMAN
NC score	0.257108 (rank : 182)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	341	Target Neighborhood Hits	177	Shared Neighborhood Hits	132
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

LNX2_HUMAN
NC score	0.256690 (rank : 183)	θ value	0.0330416 (rank : 147)
Query Neighborhood Hits	341	Target Neighborhood Hits	389	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PML_MOUSE
NC score	0.253692 (rank : 184)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	341	Target Neighborhood Hits	246	Shared Neighborhood Hits	126
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PCGF4_MOUSE
NC score	0.247341 (rank : 185)	θ value	0.0148317 (rank : 138)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	111
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.247091 (rank : 186)	θ value	0.0148317 (rank : 137)
Query Neighborhood Hits	341	Target Neighborhood Hits	161	Shared Neighborhood Hits	112
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRI45_HUMAN
NC score	0.244595 (rank : 187)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	341	Target Neighborhood Hits	155	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

PZRN3_MOUSE
NC score	0.239182 (rank : 188)	θ value	0.00228821 (rank : 117)
Query Neighborhood Hits	341	Target Neighborhood Hits	447	Shared Neighborhood Hits	178
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF5_HUMAN
NC score	0.238619 (rank : 189)	θ value	0.0563607 (rank : 164)
Query Neighborhood Hits	341	Target Neighborhood Hits	396	Shared Neighborhood Hits	162
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

PCGF2_MOUSE
NC score	0.236308 (rank : 190)	θ value	0.125558 (rank : 173)
Query Neighborhood Hits	341	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PZRN3_HUMAN
NC score	0.236238 (rank : 191)	θ value	0.00228821 (rank : 116)
Query Neighborhood Hits	341	Target Neighborhood Hits	461	Shared Neighborhood Hits	177
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PCGF2_HUMAN
NC score	0.236228 (rank : 192)	θ value	0.125558 (rank : 172)
Query Neighborhood Hits	341	Target Neighborhood Hits	222	Shared Neighborhood Hits	110
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

TRI45_MOUSE
NC score	0.228661 (rank : 193)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	341	Target Neighborhood Hits	155	Shared Neighborhood Hits	98
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

PZRN4_HUMAN
NC score	0.227706 (rank : 194)	θ value	0.0431538 (rank : 156)
Query Neighborhood Hits	341	Target Neighborhood Hits	438	Shared Neighborhood Hits	174
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAF4_HUMAN
NC score	0.223469 (rank : 195)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	341	Target Neighborhood Hits	373	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TIF1B_HUMAN
NC score	0.220598 (rank : 196)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	341	Target Neighborhood Hits	312	Shared Neighborhood Hits	106
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.217089 (rank : 197)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	341	Target Neighborhood Hits	276	Shared Neighborhood Hits	99
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRAF7_HUMAN
NC score	0.204036 (rank : 198)	θ value	0.0563607 (rank : 165)
Query Neighborhood Hits	341	Target Neighborhood Hits	482	Shared Neighborhood Hits	163
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
NC score	0.203220 (rank : 199)	θ value	0.0563607 (rank : 166)
Query Neighborhood Hits	341	Target Neighborhood Hits	470	Shared Neighborhood Hits	160
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TOPRS_MOUSE
NC score	0.200112 (rank : 200)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	341	Target Neighborhood Hits	263	Shared Neighborhood Hits	125
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_MOUSE
NC score	0.199271 (rank : 201)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	341	Target Neighborhood Hits	394	Shared Neighborhood Hits	139
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TOPRS_HUMAN
NC score	0.197144 (rank : 202)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	341	Target Neighborhood Hits	286	Shared Neighborhood Hits	126
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
NC score	0.196206 (rank : 203)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	341	Target Neighborhood Hits	402	Shared Neighborhood Hits	136
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

AMFR2_HUMAN
NC score	0.193942 (rank : 204)	θ value	1.06291 (rank : 228)
Query Neighborhood Hits	341	Target Neighborhood Hits	219	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
NC score	0.192753 (rank : 205)	θ value	1.06291 (rank : 229)
Query Neighborhood Hits	341	Target Neighborhood Hits	208	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TRAF3_MOUSE
NC score	0.191676 (rank : 206)	θ value	1.06291 (rank : 235)
Query Neighborhood Hits	341	Target Neighborhood Hits	476	Shared Neighborhood Hits	178
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RBBP6_MOUSE
NC score	0.190921 (rank : 207)	θ value	0.00665767 (rank : 130)
Query Neighborhood Hits	341	Target Neighborhood Hits	1014	Shared Neighborhood Hits	152
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_MOUSE
NC score	0.188677 (rank : 208)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	341	Target Neighborhood Hits	244	Shared Neighborhood Hits	115
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRAF3_HUMAN
NC score	0.183076 (rank : 209)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	341	Target Neighborhood Hits	463	Shared Neighborhood Hits	167
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

RC3H1_HUMAN
NC score	0.181228 (rank : 210)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	341	Target Neighborhood Hits	433	Shared Neighborhood Hits	120
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TRAIP_HUMAN
NC score	0.177625 (rank : 211)	θ value	0.0736092 (rank : 169)
Query Neighborhood Hits	341	Target Neighborhood Hits	780	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

BT3A2_HUMAN
NC score	0.177545 (rank : 212)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	341	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

RBBP6_HUMAN
NC score	0.175040 (rank : 213)	θ value	0.00665767 (rank : 129)
Query Neighborhood Hits	341	Target Neighborhood Hits	1135	Shared Neighborhood Hits	162
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NHLC1_MOUSE
NC score	0.173013 (rank : 214)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	341	Target Neighborhood Hits	103	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

BTNL1_MOUSE
NC score	0.172045 (rank : 215)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	341	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

TIF1A_HUMAN
NC score	0.171135 (rank : 216)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	341	Target Neighborhood Hits	327	Shared Neighborhood Hits	98
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

CBL_HUMAN
NC score	0.168536 (rank : 217)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	341	Target Neighborhood Hits	353	Shared Neighborhood Hits	148
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

BTNL2_HUMAN
NC score	0.165972 (rank : 218)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	341	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CBL_MOUSE
NC score	0.165206 (rank : 219)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	341	Target Neighborhood Hits	426	Shared Neighborhood Hits	151
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RN152_MOUSE
NC score	0.164895 (rank : 220)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	341	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

NHLC1_HUMAN
NC score	0.163506 (rank : 221)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	341	Target Neighborhood Hits	91	Shared Neighborhood Hits	66
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAIP_MOUSE
NC score	0.161489 (rank : 222)	θ value	0.0961366 (rank : 171)
Query Neighborhood Hits	341	Target Neighborhood Hits	745	Shared Neighborhood Hits	135
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

CBLB_MOUSE
NC score	0.161172 (rank : 223)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	341	Target Neighborhood Hits	277	Shared Neighborhood Hits	143
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_MOUSE
NC score	0.160575 (rank : 224)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	341	Target Neighborhood Hits	186	Shared Neighborhood Hits	133
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBLC_HUMAN
NC score	0.160462 (rank : 225)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	341	Target Neighborhood Hits	173	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLB_HUMAN
NC score	0.160313 (rank : 226)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	341	Target Neighborhood Hits	261	Shared Neighborhood Hits	143
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

MOG_HUMAN
NC score	0.159501 (rank : 227)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	341	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

RN152_HUMAN
NC score	0.159407 (rank : 228)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	341	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

MOG_MOUSE
NC score	0.159117 (rank : 229)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	341	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

DTX3L_HUMAN
NC score	0.150628 (rank : 230)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	341	Target Neighborhood Hits	187	Shared Neighborhood Hits	117
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

MAT1_HUMAN
NC score	0.149151 (rank : 231)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	341	Target Neighborhood Hits	179	Shared Neighborhood Hits	62
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

BARD1_HUMAN
NC score	0.147277 (rank : 232)	θ value	0.0252991 (rank : 141)
Query Neighborhood Hits	341	Target Neighborhood Hits	427	Shared Neighborhood Hits	100
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MAT1_MOUSE
NC score	0.147042 (rank : 233)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	341	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

TIF1A_MOUSE
NC score	0.146105 (rank : 234)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	341	Target Neighborhood Hits	307	Shared Neighborhood Hits	91
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BARD1_MOUSE
NC score	0.145932 (rank : 235)	θ value	0.00665767 (rank : 127)
Query Neighborhood Hits	341	Target Neighborhood Hits	411	Shared Neighborhood Hits	97
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BIRC8_HUMAN
NC score	0.141703 (rank : 236)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	341	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

RKHD1_HUMAN
NC score	0.141041 (rank : 237)	θ value	0.47712 (rank : 207)
Query Neighborhood Hits	341	Target Neighborhood Hits	163	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TRAF4_MOUSE
NC score	0.136002 (rank : 238)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	341	Target Neighborhood Hits	338	Shared Neighborhood Hits	113
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

RNF34_MOUSE
NC score	0.135462 (rank : 239)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	341	Target Neighborhood Hits	160	Shared Neighborhood Hits	84
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

MNAB_HUMAN
NC score	0.134740 (rank : 240)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	341	Target Neighborhood Hits	196	Shared Neighborhood Hits	96
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
NC score	0.133047 (rank : 241)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	341	Target Neighborhood Hits	231	Shared Neighborhood Hits	95
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RNF34_HUMAN
NC score	0.132600 (rank : 242)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	341	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

MGRN1_MOUSE
NC score	0.130989 (rank : 243)	θ value	0.47712 (rank : 202)
Query Neighborhood Hits	341	Target Neighborhood Hits	149	Shared Neighborhood Hits	98
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.128212 (rank : 244)	θ value	0.47712 (rank : 201)
Query Neighborhood Hits	341	Target Neighborhood Hits	192	Shared Neighborhood Hits	101
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

BIRC3_HUMAN
NC score	0.123884 (rank : 245)	θ value	0.47712 (rank : 200)
Query Neighborhood Hits	341	Target Neighborhood Hits	133	Shared Neighborhood Hits	83
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

ARD1_MOUSE
NC score	0.123125 (rank : 246)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	341	Target Neighborhood Hits	573	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

CNOT4_HUMAN
NC score	0.123117 (rank : 247)	θ value	0.279714 (rank : 182)
Query Neighborhood Hits	341	Target Neighborhood Hits	207	Shared Neighborhood Hits	43
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RNF32_HUMAN
NC score	0.121094 (rank : 248)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	341	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

BIRC2_HUMAN
NC score	0.120922 (rank : 249)	θ value	0.47712 (rank : 199)
Query Neighborhood Hits	341	Target Neighborhood Hits	142	Shared Neighborhood Hits	90
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

ARD1_HUMAN
NC score	0.120067 (rank : 250)	θ value	0.365318 (rank : 189)
Query Neighborhood Hits	341	Target Neighborhood Hits	621	Shared Neighborhood Hits	80
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

UB7I3_MOUSE
NC score	0.120061 (rank : 251)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	341	Target Neighborhood Hits	131	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

CNOT4_MOUSE
NC score	0.117071 (rank : 252)	θ value	0.279714 (rank : 183)
Query Neighborhood Hits	341	Target Neighborhood Hits	277	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BIRC2_MOUSE
NC score	0.116383 (rank : 253)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	341	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

NEUL1_HUMAN
NC score	0.114389 (rank : 254)	θ value	0.62314 (rank : 217)
Query Neighborhood Hits	341	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

BRE1B_MOUSE
NC score	0.114129 (rank : 255)	θ value	2.36792 (rank : 252)
Query Neighborhood Hits	341	Target Neighborhood Hits	970	Shared Neighborhood Hits	206
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

NEURL_MOUSE
NC score	0.113665 (rank : 256)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	341	Target Neighborhood Hits	106	Shared Neighborhood Hits	69
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

BRE1B_HUMAN
NC score	0.112703 (rank : 257)	θ value	2.36792 (rank : 251)
Query Neighborhood Hits	341	Target Neighborhood Hits	1040	Shared Neighborhood Hits	209
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

RN123_MOUSE
NC score	0.108298 (rank : 258)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	341	Target Neighborhood Hits	174	Shared Neighborhood Hits	114
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RNF32_MOUSE
NC score	0.106645 (rank : 259)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	341	Target Neighborhood Hits	129	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RN123_HUMAN
NC score	0.106018 (rank : 260)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	341	Target Neighborhood Hits	175	Shared Neighborhood Hits	111
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

PJA1_HUMAN
NC score	0.103266 (rank : 261)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	341	Target Neighborhood Hits	159	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

BIRC3_MOUSE
NC score	0.100301 (rank : 262)	θ value	2.36792 (rank : 250)
Query Neighborhood Hits	341	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

UB7I3_HUMAN
NC score	0.099818 (rank : 263)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	341	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RNF26_HUMAN
NC score	0.095783 (rank : 264)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	341	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

BRAP_HUMAN
NC score	0.095353 (rank : 265)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	341	Target Neighborhood Hits	560	Shared Neighborhood Hits	122
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RFFL_HUMAN
NC score	0.095038 (rank : 266)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	341	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

BRE1A_HUMAN
NC score	0.094782 (rank : 267)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	341	Target Neighborhood Hits	1071	Shared Neighborhood Hits	203
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
NC score	0.092628 (rank : 268)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	341	Target Neighborhood Hits	1025	Shared Neighborhood Hits	198
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

RFFL_MOUSE
NC score	0.092622 (rank : 269)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	341	Target Neighborhood Hits	145	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

CD276_MOUSE
NC score	0.092307 (rank : 270)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	341	Target Neighborhood Hits	243	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

MKRN2_MOUSE
NC score	0.089243 (rank : 271)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	341	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN2_HUMAN
NC score	0.087599 (rank : 272)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	341	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN4_HUMAN
NC score	0.086970 (rank : 273)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	341	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

FSD1L_MOUSE
NC score	0.085850 (rank : 274)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	341	Target Neighborhood Hits	78	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

RNF37_MOUSE
NC score	0.084441 (rank : 275)	θ value	0.0252991 (rank : 145)
Query Neighborhood Hits	341	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

PEX2_MOUSE
NC score	0.083153 (rank : 276)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	341	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

PJA1_MOUSE
NC score	0.083120 (rank : 277)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	341	Target Neighborhood Hits	145	Shared Neighborhood Hits	61
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

CD276_HUMAN
NC score	0.082628 (rank : 278)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	341	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

ICOSL_HUMAN
NC score	0.082402 (rank : 279)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	341	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

BRAP_MOUSE
NC score	0.081938 (rank : 280)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	341	Target Neighborhood Hits	409	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

ZSWM2_HUMAN
NC score	0.081256 (rank : 281)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	341	Target Neighborhood Hits	151	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

TRI66_MOUSE
NC score	0.081163 (rank : 282)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	341	Target Neighborhood Hits	491	Shared Neighborhood Hits	78
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

MIB1_MOUSE
NC score	0.080867 (rank : 283)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	341	Target Neighborhood Hits	471	Shared Neighborhood Hits	107
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.080696 (rank : 284)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	341	Target Neighborhood Hits	470	Shared Neighborhood Hits	106
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

PDL1_MOUSE
NC score	0.078162 (rank : 285)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	341	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

FSD1L_HUMAN
NC score	0.077665 (rank : 286)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	341	Target Neighborhood Hits	57	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

TRI66_HUMAN
NC score	0.077028 (rank : 287)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	341	Target Neighborhood Hits	479	Shared Neighborhood Hits	76
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RN103_HUMAN
NC score	0.073930 (rank : 288)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	341	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
NC score	0.073915 (rank : 289)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

MKRN3_HUMAN
NC score	0.073592 (rank : 290)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	341	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

LRSM1_HUMAN
NC score	0.072936 (rank : 291)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	341	Target Neighborhood Hits	1078	Shared Neighborhood Hits	157
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

HHLA2_HUMAN
NC score	0.071986 (rank : 292)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	341	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

CD86_HUMAN
NC score	0.071328 (rank : 293)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	341	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

RN122_HUMAN
NC score	0.071198 (rank : 294)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	341	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF37_HUMAN
NC score	0.070564 (rank : 295)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	341	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

MIB2_HUMAN
NC score	0.069764 (rank : 296)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	341	Target Neighborhood Hits	438	Shared Neighborhood Hits	96
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CD86_MOUSE
NC score	0.068279 (rank : 297)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	341	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

GOGA4_MOUSE
NC score	0.067392 (rank : 298)	θ value	0.0113563 (rank : 135)
Query Neighborhood Hits	341	Target Neighborhood Hits	1939	Shared Neighborhood Hits	156
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RN165_HUMAN
NC score	0.065823 (rank : 299)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	341	Target Neighborhood Hits	151	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

PDL2_HUMAN
NC score	0.065729 (rank : 300)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	341	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

SIAH2_HUMAN
NC score	0.065578 (rank : 301)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	341	Target Neighborhood Hits	94	Shared Neighborhood Hits	58
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

RN126_MOUSE
NC score	0.065440 (rank : 302)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	341	Target Neighborhood Hits	143	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZN364_HUMAN
NC score	0.065348 (rank : 303)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	341	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RN167_MOUSE
NC score	0.065288 (rank : 304)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	341	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

BIRC4_HUMAN
NC score	0.065283 (rank : 305)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	341	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

ICOSL_MOUSE
NC score	0.065166 (rank : 306)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	341	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

SIAH2_MOUSE
NC score	0.065150 (rank : 307)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	341	Target Neighborhood Hits	101	Shared Neighborhood Hits	57
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

RN122_MOUSE
NC score	0.064929 (rank : 308)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	341	Target Neighborhood Hits	121	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BIRC4_MOUSE
NC score	0.064719 (rank : 309)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	341	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

LRSM1_MOUSE
NC score	0.063212 (rank : 310)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	341	Target Neighborhood Hits	874	Shared Neighborhood Hits	149
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MIB2_MOUSE
NC score	0.062799 (rank : 311)	θ value	1.06291 (rank : 231)
Query Neighborhood Hits	341	Target Neighborhood Hits	409	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MKRN1_HUMAN
NC score	0.062796 (rank : 312)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	341	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

CP250_HUMAN
NC score	0.062600 (rank : 313)	θ value	1.06291 (rank : 230)
Query Neighborhood Hits	341	Target Neighborhood Hits	1805	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GOGB1_HUMAN
NC score	0.062126 (rank : 314)	θ value	0.365318 (rank : 190)
Query Neighborhood Hits	341	Target Neighborhood Hits	2297	Shared Neighborhood Hits	174
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MKRN1_MOUSE
NC score	0.061737 (rank : 315)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	341	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

ZSWM2_MOUSE
NC score	0.061695 (rank : 316)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	341	Target Neighborhood Hits	132	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

PDL2_MOUSE
NC score	0.061474 (rank : 317)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	341	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

RN167_HUMAN
NC score	0.059801 (rank : 318)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	341	Target Neighborhood Hits	157	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

CENPF_HUMAN
NC score	0.059208 (rank : 319)	θ value	2.36792 (rank : 253)
Query Neighborhood Hits	341	Target Neighborhood Hits	1932	Shared Neighborhood Hits	155
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ZN364_MOUSE
NC score	0.058607 (rank : 320)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	341	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

CCD46_HUMAN
NC score	0.058542 (rank : 321)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	341	Target Neighborhood Hits	1430	Shared Neighborhood Hits	149
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GCC2_MOUSE
NC score	0.058240 (rank : 322)	θ value	6.88961 (rank : 315)
Query Neighborhood Hits	341	Target Neighborhood Hits	1619	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA4_HUMAN
NC score	0.058220 (rank : 323)	θ value	0.813845 (rank : 222)
Query Neighborhood Hits	341	Target Neighborhood Hits	2034	Shared Neighborhood Hits	161
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CF060_HUMAN
NC score	0.058001 (rank : 324)	θ value	0.0431538 (rank : 153)
Query Neighborhood Hits	341	Target Neighborhood Hits	1270	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

PDL1_HUMAN
NC score	0.057369 (rank : 325)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	341	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

SYCP1_MOUSE
NC score	0.057202 (rank : 326)	θ value	1.38821 (rank : 238)
Query Neighborhood Hits	341	Target Neighborhood Hits	1456	Shared Neighborhood Hits	135
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MKRN3_MOUSE
NC score	0.056986 (rank : 327)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	341	Target Neighborhood Hits	137	Shared Neighborhood Hits	53
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

RN126_HUMAN
NC score	0.056579 (rank : 328)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	341	Target Neighborhood Hits	126	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

MYLIP_HUMAN
NC score	0.056077 (rank : 329)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	341	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RNF17_MOUSE
NC score	0.055835 (rank : 330)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	341	Target Neighborhood Hits	147	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

AZI1_MOUSE
NC score	0.055221 (rank : 331)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	341	Target Neighborhood Hits	990	Shared Neighborhood Hits	100
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

GCC1_HUMAN
NC score	0.055070 (rank : 332)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	341	Target Neighborhood Hits	887	Shared Neighborhood Hits	108
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

PEX2_HUMAN
NC score	0.054995 (rank : 333)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	341	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

TRIPB_HUMAN
NC score	0.054321 (rank : 334)	θ value	0.00390308 (rank : 123)
Query Neighborhood Hits	341	Target Neighborhood Hits	1587	Shared Neighborhood Hits	134
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TTC3_HUMAN
NC score	0.054283 (rank : 335)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	341	Target Neighborhood Hits	664	Shared Neighborhood Hits	106
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

NIN_HUMAN
NC score	0.053700 (rank : 336)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	341	Target Neighborhood Hits	1416	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CENPE_HUMAN
NC score	0.053467 (rank : 337)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	341	Target Neighborhood Hits	2060	Shared Neighborhood Hits	155
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

AZI1_HUMAN
NC score	0.053451 (rank : 338)	θ value	6.88961 (rank : 307)
Query Neighborhood Hits	341	Target Neighborhood Hits	1000	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

RNF19_HUMAN
NC score	0.053440 (rank : 339)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	341	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

PCNT_HUMAN
NC score	0.053358 (rank : 340)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	341	Target Neighborhood Hits	1551	Shared Neighborhood Hits	130
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RNF19_MOUSE
NC score	0.053262 (rank : 341)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	341	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

CCD41_MOUSE
NC score	0.052933 (rank : 342)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	341	Target Neighborhood Hits	1399	Shared Neighborhood Hits	130
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

RNF13_HUMAN
NC score	0.052751 (rank : 343)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	341	Target Neighborhood Hits	147	Shared Neighborhood Hits	60
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

CP250_MOUSE
NC score	0.052672 (rank : 344)	θ value	2.36792 (rank : 254)
Query Neighborhood Hits	341	Target Neighborhood Hits	1583	Shared Neighborhood Hits	140
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CCD46_MOUSE
NC score	0.052334 (rank : 345)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	341	Target Neighborhood Hits	1405	Shared Neighborhood Hits	136
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RNF24_MOUSE
NC score	0.052203 (rank : 346)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	341	Target Neighborhood Hits	124	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.052006 (rank : 347)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	341	Target Neighborhood Hits	122	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF13_MOUSE
NC score	0.051573 (rank : 348)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	341	Target Neighborhood Hits	164	Shared Neighborhood Hits	68
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RBP24_HUMAN
NC score	0.051496 (rank : 349)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	341	Target Neighborhood Hits	1559	Shared Neighborhood Hits	150
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.051308 (rank : 350)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	341	Target Neighborhood Hits	1558	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CE290_HUMAN
NC score	0.050917 (rank : 351)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	341	Target Neighborhood Hits	1553	Shared Neighborhood Hits	143
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TPR_HUMAN
NC score	0.050632 (rank : 352)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	341	Target Neighborhood Hits	1921	Shared Neighborhood Hits	145
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

DZIP3_MOUSE
NC score	0.050463 (rank : 353)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	341	Target Neighborhood Hits	414	Shared Neighborhood Hits	100
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

TRHY_HUMAN
NC score	0.049581 (rank : 354)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	341	Target Neighborhood Hits	1385	Shared Neighborhood Hits	110
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ANR26_HUMAN
NC score	0.049087 (rank : 355)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	341	Target Neighborhood Hits	1614	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GOGA6_HUMAN
NC score	0.048506 (rank : 356)	θ value	0.279714 (rank : 184)
Query Neighborhood Hits	341	Target Neighborhood Hits	1007	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

SDCG8_HUMAN
NC score	0.048429 (rank : 357)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	341	Target Neighborhood Hits	1002	Shared Neighborhood Hits	113
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

T3JAM_HUMAN
NC score	0.047525 (rank : 358)	θ value	1.38821 (rank : 239)
Query Neighborhood Hits	341	Target Neighborhood Hits	533	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CCD91_HUMAN
NC score	0.046926 (rank : 359)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	341	Target Neighborhood Hits	868	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CEP63_HUMAN
NC score	0.046891 (rank : 360)	θ value	0.163984 (rank : 176)
Query Neighborhood Hits	341	Target Neighborhood Hits	1005	Shared Neighborhood Hits	109
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

PHLB2_MOUSE
NC score	0.045136 (rank : 361)	θ value	3.0926 (rank : 274)
Query Neighborhood Hits	341	Target Neighborhood Hits	1016	Shared Neighborhood Hits	102
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SMC2_HUMAN
NC score	0.044530 (rank : 362)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	341	Target Neighborhood Hits	1405	Shared Neighborhood Hits	115
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CT116_HUMAN
NC score	0.043786 (rank : 363)	θ value	1.81305 (rank : 244)
Query Neighborhood Hits	341	Target Neighborhood Hits	294	Shared Neighborhood Hits	47
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

MYH11_MOUSE
NC score	0.042556 (rank : 364)	θ value	1.38821 (rank : 237)
Query Neighborhood Hits	341	Target Neighborhood Hits	1777	Shared Neighborhood Hits	145
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CYLN2_MOUSE
NC score	0.042399 (rank : 365)	θ value	6.88961 (rank : 312)
Query Neighborhood Hits	341	Target Neighborhood Hits	1002	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

SWP70_MOUSE
NC score	0.041973 (rank : 366)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	341	Target Neighborhood Hits	1097	Shared Neighborhood Hits	111
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PHLB2_HUMAN
NC score	0.041416 (rank : 367)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	341	Target Neighborhood Hits	964	Shared Neighborhood Hits	97
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

REST_MOUSE
NC score	0.041105 (rank : 368)	θ value	6.88961 (rank : 318)
Query Neighborhood Hits	341	Target Neighborhood Hits	1506	Shared Neighborhood Hits	124
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SMC1A_HUMAN
NC score	0.040869 (rank : 369)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	341	Target Neighborhood Hits	1346	Shared Neighborhood Hits	120
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.040602 (rank : 370)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	341	Target Neighborhood Hits	1384	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

FYCO1_HUMAN
NC score	0.040544 (rank : 371)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	341	Target Neighborhood Hits	1149	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MYH10_MOUSE
NC score	0.040431 (rank : 372)	θ value	1.06291 (rank : 232)
Query Neighborhood Hits	341	Target Neighborhood Hits	1612	Shared Neighborhood Hits	142
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.039943 (rank : 373)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	341	Target Neighborhood Hits	1620	Shared Neighborhood Hits	144
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

GOGA2_MOUSE
NC score	0.039885 (rank : 374)	θ value	3.0926 (rank : 267)
Query Neighborhood Hits	341	Target Neighborhood Hits	944	Shared Neighborhood Hits	107
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

BPAEA_MOUSE
NC score	0.039681 (rank : 375)	θ value	6.88961 (rank : 308)
Query Neighborhood Hits	341	Target Neighborhood Hits	1480	Shared Neighborhood Hits	127
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MD1L1_MOUSE
NC score	0.039605 (rank : 376)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	341	Target Neighborhood Hits	1001	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

CE152_HUMAN
NC score	0.039112 (rank : 377)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	341	Target Neighborhood Hits	976	Shared Neighborhood Hits	102
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CK5P2_HUMAN
NC score	0.038931 (rank : 378)	θ value	3.0926 (rank : 265)
Query Neighborhood Hits	341	Target Neighborhood Hits	1433	Shared Neighborhood Hits	119
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

ANR26_MOUSE
NC score	0.038680 (rank : 379)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	341	Target Neighborhood Hits	1554	Shared Neighborhood Hits	126
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CT116_MOUSE
NC score	0.038662 (rank : 380)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	341	Target Neighborhood Hits	268	Shared Neighborhood Hits	43
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

SPAG5_MOUSE
NC score	0.038216 (rank : 381)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	341	Target Neighborhood Hits	612	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

EP15_MOUSE
NC score	0.038099 (rank : 382)	θ value	6.88961 (rank : 314)
Query Neighborhood Hits	341	Target Neighborhood Hits	820	Shared Neighborhood Hits	88
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

SYNE2_HUMAN
NC score	0.038072 (rank : 383)	θ value	1.06291 (rank : 233)
Query Neighborhood Hits	341	Target Neighborhood Hits	1323	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CCD91_MOUSE
NC score	0.037163 (rank : 384)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	341	Target Neighborhood Hits	699	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

PLEC1_HUMAN
NC score	0.036135 (rank : 385)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	341	Target Neighborhood Hits	1326	Shared Neighborhood Hits	119
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SWP70_HUMAN
NC score	0.035083 (rank : 386)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	341	Target Neighborhood Hits	973	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MYH14_MOUSE
NC score	0.034817 (rank : 387)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	341	Target Neighborhood Hits	1225	Shared Neighborhood Hits	123
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CCD42_HUMAN
NC score	0.034775 (rank : 388)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	341	Target Neighborhood Hits	406	Shared Neighborhood Hits	66
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CJ118_HUMAN
NC score	0.033037 (rank : 389)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	341	Target Neighborhood Hits	937	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

RNF17_HUMAN
NC score	0.032801 (rank : 390)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	341	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

CCD42_MOUSE
NC score	0.032768 (rank : 391)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	341	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

HOOK3_MOUSE
NC score	0.032084 (rank : 392)	θ value	3.0926 (rank : 268)
Query Neighborhood Hits	341	Target Neighborhood Hits	1007	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.032012 (rank : 393)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	341	Target Neighborhood Hits	1070	Shared Neighborhood Hits	103
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

ZRF1_MOUSE
NC score	0.031757 (rank : 394)	θ value	0.21417 (rank : 181)
Query Neighborhood Hits	341	Target Neighborhood Hits	414	Shared Neighborhood Hits	50
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

MYH13_HUMAN
NC score	0.029411 (rank : 395)	θ value	3.0926 (rank : 273)
Query Neighborhood Hits	341	Target Neighborhood Hits	1504	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

GAS8_HUMAN
NC score	0.029355 (rank : 396)	θ value	2.36792 (rank : 257)
Query Neighborhood Hits	341	Target Neighborhood Hits	819	Shared Neighborhood Hits	89
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MYH14_HUMAN
NC score	0.028867 (rank : 397)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	341	Target Neighborhood Hits	995	Shared Neighborhood Hits	103
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

U2AFM_HUMAN
NC score	0.027080 (rank : 398)	θ value	1.81305 (rank : 248)
Query Neighborhood Hits	341	Target Neighborhood Hits	577	Shared Neighborhood Hits	66
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

KIF5C_MOUSE
NC score	0.026005 (rank : 399)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	341	Target Neighborhood Hits	1040	Shared Neighborhood Hits	100
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

DAAM1_HUMAN
NC score	0.025525 (rank : 400)	θ value	0.0431538 (rank : 155)
Query Neighborhood Hits	341	Target Neighborhood Hits	483	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

KIF5C_HUMAN
NC score	0.025275 (rank : 401)	θ value	3.0926 (rank : 269)
Query Neighborhood Hits	341	Target Neighborhood Hits	974	Shared Neighborhood Hits	100
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CDR2_MOUSE
NC score	0.024718 (rank : 402)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	341	Target Neighborhood Hits	482	Shared Neighborhood Hits	70
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

DAAM1_MOUSE
NC score	0.024678 (rank : 403)	θ value	0.0736092 (rank : 168)
Query Neighborhood Hits	341	Target Neighborhood Hits	443	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

LIPB2_MOUSE
NC score	0.021588 (rank : 404)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	341	Target Neighborhood Hits	570	Shared Neighborhood Hits	69
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

ENAH_MOUSE
NC score	0.020783 (rank : 405)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	341	Target Neighborhood Hits	919	Shared Neighborhood Hits	64
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TRAK2_HUMAN
NC score	0.020711 (rank : 406)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	341	Target Neighborhood Hits	476	Shared Neighborhood Hits	63
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

CCD93_MOUSE
NC score	0.020362 (rank : 407)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	341	Target Neighborhood Hits	362	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

KIF5A_HUMAN
NC score	0.020275 (rank : 408)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	341	Target Neighborhood Hits	843	Shared Neighborhood Hits	85
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
NC score	0.018775 (rank : 409)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	341	Target Neighborhood Hits	859	Shared Neighborhood Hits	85
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

GBP1_MOUSE
NC score	0.018070 (rank : 410)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	341	Target Neighborhood Hits	302	Shared Neighborhood Hits	49
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

SPTA1_MOUSE
NC score	0.017246 (rank : 411)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	341	Target Neighborhood Hits	675	Shared Neighborhood Hits	67
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ASPP1_HUMAN
NC score	0.016869 (rank : 412)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	341	Target Neighborhood Hits	956	Shared Neighborhood Hits	69
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RIR1_MOUSE
NC score	0.014981 (rank : 413)	θ value	1.81305 (rank : 246)
Query Neighborhood Hits	341	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P07742	Gene names	Rrm1
Domain Architecture
Description	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase M1 subunit) (Ribonucleotide reductase large chain).

CTRO_MOUSE
NC score	0.014619 (rank : 414)	θ value	3.0926 (rank : 266)
Query Neighborhood Hits	341	Target Neighborhood Hits	2344	Shared Neighborhood Hits	133
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ASPP1_MOUSE
NC score	0.013926 (rank : 415)	θ value	2.36792 (rank : 249)
Query Neighborhood Hits	341	Target Neighborhood Hits	1244	Shared Neighborhood Hits	72
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DNL4_HUMAN
NC score	0.013741 (rank : 416)	θ value	2.36792 (rank : 255)
Query Neighborhood Hits	341	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL4_MOUSE
NC score	0.013732 (rank : 417)	θ value	2.36792 (rank : 256)
Query Neighborhood Hits	341	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

MRCKB_MOUSE
NC score	0.013409 (rank : 418)	θ value	3.0926 (rank : 272)
Query Neighborhood Hits	341	Target Neighborhood Hits	2180	Shared Neighborhood Hits	126
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RIR1_HUMAN
NC score	0.012273 (rank : 419)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	341	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P23921, Q9UNN2	Gene names	RRM1, RR1
Domain Architecture
Description	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase M1 subunit) (Ribonucleotide reductase large chain).

CTRO_HUMAN
NC score	0.012246 (rank : 420)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	341	Target Neighborhood Hits	2092	Shared Neighborhood Hits	116
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

RF1M_MOUSE
NC score	0.011515 (rank : 421)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	341	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K126	Gene names	Mtrf1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

TFAM_HUMAN
NC score	0.010785 (rank : 422)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	341	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

MYO7A_HUMAN
NC score	0.006764 (rank : 423)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	341	Target Neighborhood Hits	209	Shared Neighborhood Hits	21
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

M4K4_MOUSE
NC score	0.003429 (rank : 424)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	341	Target Neighborhood Hits	1560	Shared Neighborhood Hits	76
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.003280 (rank : 425)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	341	Target Neighborhood Hits	1589	Shared Neighborhood Hits	83
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

KR10C_HUMAN
NC score	0.003062 (rank : 426)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	341	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA24_HUMAN
NC score	0.002681 (rank : 427)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	341	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

DCE2_HUMAN
NC score	0.002562 (rank : 428)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	341	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

WDR47_MOUSE
NC score	0.002391 (rank : 429)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	341	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

PLSL_MOUSE
NC score	0.001692 (rank : 430)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	341	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

TNIK_HUMAN
NC score	0.000417 (rank : 431)	θ value	1.06291 (rank : 234)
Query Neighborhood Hits	341	Target Neighborhood Hits	1570	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

KR105_HUMAN
NC score	0.000276 (rank : 432)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	341	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

DUOX2_HUMAN
NC score	-0.000336 (rank : 433)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	341	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

M3K1_MOUSE
NC score	-0.001924 (rank : 434)	θ value	0.163984 (rank : 177)
Query Neighborhood Hits	341	Target Neighborhood Hits	952	Shared Neighborhood Hits	21
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

TRIO_HUMAN
NC score	-0.003480 (rank : 435)	θ value	1.81305 (rank : 247)
Query Neighborhood Hits	341	Target Neighborhood Hits	1580	Shared Neighborhood Hits	77
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

ZN406_HUMAN
NC score	-0.008240 (rank : 436)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	341	Target Neighborhood Hits	794	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P243, Q3MIM5, Q6PJ01, Q75PJ7, Q75PJ9, Q86X64	Gene names	ZNF406, KIAA1485
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406 (Protein ZFAT).

ZN406_MOUSE
NC score	-0.008602 (rank : 437)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	341	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.