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Network neighborhood for query Sequence : MKRN3_MOUSE

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MKRN3_MOUSE
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MKRN3_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	137
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MKRN3_HUMAN
θ value	7.78761e-153 (rank : 2)	NC score	0.976533 (rank : 2)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	96
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN1_MOUSE
θ value	6.47494e-99 (rank : 3)	NC score	0.951780 (rank : 5)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN1_HUMAN
θ value	9.34977e-98 (rank : 4)	NC score	0.952173 (rank : 4)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN4_HUMAN
θ value	9.6755e-95 (rank : 5)	NC score	0.960626 (rank : 3)
Query Neighborhood Hits	137	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MKRN2_HUMAN
θ value	6.53529e-67 (rank : 6)	NC score	0.915818 (rank : 6)
Query Neighborhood Hits	137	Target Neighborhood Hits	129	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	3.24342e-66 (rank : 7)	NC score	0.911630 (rank : 7)
Query Neighborhood Hits	137	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

TRAIP_HUMAN
θ value	0.00869519 (rank : 8)	NC score	0.113098 (rank : 46)
Query Neighborhood Hits	137	Target Neighborhood Hits	780	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	0.00869519 (rank : 9)	NC score	0.110524 (rank : 47)
Query Neighborhood Hits	137	Target Neighborhood Hits	745	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI22_HUMAN
θ value	0.00869519 (rank : 10)	NC score	0.102756 (rank : 56)
Query Neighborhood Hits	137	Target Neighborhood Hits	396	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

RN141_HUMAN
θ value	0.0330416 (rank : 11)	NC score	0.199947 (rank : 17)
Query Neighborhood Hits	137	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.0330416 (rank : 12)	NC score	0.198464 (rank : 18)
Query Neighborhood Hits	137	Target Neighborhood Hits	200	Shared Neighborhood Hits	65
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

CS007_HUMAN
θ value	0.0431538 (rank : 13)	NC score	0.258077 (rank : 14)
Query Neighborhood Hits	137	Target Neighborhood Hits	401	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	0.0431538 (rank : 14)	NC score	0.254766 (rank : 15)
Query Neighborhood Hits	137	Target Neighborhood Hits	464	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

PEX10_HUMAN
θ value	0.0431538 (rank : 15)	NC score	0.210181 (rank : 16)
Query Neighborhood Hits	137	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF19_HUMAN
θ value	0.0563607 (rank : 16)	NC score	0.145209 (rank : 29)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	0.0563607 (rank : 17)	NC score	0.145662 (rank : 27)
Query Neighborhood Hits	137	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

TACC3_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.032342 (rank : 186)
Query Neighborhood Hits	137	Target Neighborhood Hits	779	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ZSWM2_HUMAN
θ value	0.0563607 (rank : 19)	NC score	0.165390 (rank : 25)
Query Neighborhood Hits	137	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZC3H6_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.263803 (rank : 13)
Query Neighborhood Hits	137	Target Neighborhood Hits	228	Shared Neighborhood Hits	36
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZC3H6_MOUSE
θ value	0.0736092 (rank : 21)	NC score	0.272865 (rank : 10)
Query Neighborhood Hits	137	Target Neighborhood Hits	239	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

PAR12_HUMAN
θ value	0.0961366 (rank : 22)	NC score	0.123029 (rank : 36)
Query Neighborhood Hits	137	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

RNF13_MOUSE
θ value	0.125558 (rank : 23)	NC score	0.114190 (rank : 45)
Query Neighborhood Hits	137	Target Neighborhood Hits	164	Shared Neighborhood Hits	42
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

CPSF4_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.268602 (rank : 11)
Query Neighborhood Hits	137	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

CPSF4_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.267134 (rank : 12)
Query Neighborhood Hits	137	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

RN125_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.114626 (rank : 44)
Query Neighborhood Hits	137	Target Neighborhood Hits	220	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RAPSN_HUMAN
θ value	0.21417 (rank : 27)	NC score	0.087742 (rank : 81)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

ZC3H8_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.316115 (rank : 8)
Query Neighborhood Hits	137	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

RNF13_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.105813 (rank : 53)
Query Neighborhood Hits	137	Target Neighborhood Hits	147	Shared Neighborhood Hits	39
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

TRI65_HUMAN
θ value	0.279714 (rank : 30)	NC score	0.120683 (rank : 39)
Query Neighborhood Hits	137	Target Neighborhood Hits	330	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM2_HUMAN
θ value	0.279714 (rank : 31)	NC score	0.106687 (rank : 51)
Query Neighborhood Hits	137	Target Neighborhood Hits	330	Shared Neighborhood Hits	72
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.106422 (rank : 52)
Query Neighborhood Hits	137	Target Neighborhood Hits	331	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

DHX57_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.071118 (rank : 108)
Query Neighborhood Hits	137	Target Neighborhood Hits	109	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

MBNL_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.090588 (rank : 74)
Query Neighborhood Hits	137	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR56, O43311, O43797	Gene names	MBNL1, EXP, KIAA0428, MBNL
Domain Architecture
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

MBNL_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.087158 (rank : 82)
Query Neighborhood Hits	137	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JKP5	Gene names	Mbnl1, Exp, Mbnl
Domain Architecture	No domain graphic available
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

RN168_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.121425 (rank : 38)
Query Neighborhood Hits	137	Target Neighborhood Hits	370	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI39_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.089232 (rank : 79)
Query Neighborhood Hits	137	Target Neighborhood Hits	693	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.088165 (rank : 80)
Query Neighborhood Hits	137	Target Neighborhood Hits	691	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RAPSN_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.082119 (rank : 90)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	25
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RN168_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.128079 (rank : 34)
Query Neighborhood Hits	137	Target Neighborhood Hits	440	Shared Neighborhood Hits	51
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TTP_MOUSE
θ value	0.47712 (rank : 41)	NC score	0.186522 (rank : 19)
Query Neighborhood Hits	137	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

PAR12_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.106837 (rank : 50)
Query Neighborhood Hits	137	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

ZC3H8_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.298045 (rank : 9)
Query Neighborhood Hits	137	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

IBRD3_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.099300 (rank : 59)
Query Neighborhood Hits	137	Target Neighborhood Hits	70	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

MYCB2_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.092574 (rank : 70)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NFX1_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.057150 (rank : 145)
Query Neighborhood Hits	137	Target Neighborhood Hits	405	Shared Neighborhood Hits	15
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TRI68_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.070526 (rank : 110)
Query Neighborhood Hits	137	Target Neighborhood Hits	356	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

ZC3H5_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.082609 (rank : 88)
Query Neighborhood Hits	137	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ZC3H5_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.097035 (rank : 64)
Query Neighborhood Hits	137	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

APC11_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.129834 (rank : 33)
Query Neighborhood Hits	137	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

BRAP_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.089519 (rank : 77)
Query Neighborhood Hits	137	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.100138 (rank : 57)
Query Neighborhood Hits	137	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

MYCB2_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.086900 (rank : 83)
Query Neighborhood Hits	137	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

DHX57_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.067224 (rank : 121)
Query Neighborhood Hits	137	Target Neighborhood Hits	125	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

LNX1_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.069489 (rank : 115)
Query Neighborhood Hits	137	Target Neighborhood Hits	379	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDZD2_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.018639 (rank : 195)
Query Neighborhood Hits	137	Target Neighborhood Hits	772	Shared Neighborhood Hits	13
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RAD18_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.102859 (rank : 55)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RNF38_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.098217 (rank : 61)
Query Neighborhood Hits	137	Target Neighborhood Hits	155	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

TAU_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.019720 (rank : 193)
Query Neighborhood Hits	137	Target Neighborhood Hits	502	Shared Neighborhood Hits	10
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TRI65_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.118363 (rank : 41)
Query Neighborhood Hits	137	Target Neighborhood Hits	340	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

APC11_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.118055 (rank : 42)
Query Neighborhood Hits	137	Target Neighborhood Hits	74	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

NUPL2_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.083179 (rank : 85)
Query Neighborhood Hits	137	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	O15504, Q49AE7, Q9BS49	Gene names	NUPL2, CG1
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1) (hCG1) (NUP42 homolog).

RAD18_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.110227 (rank : 48)
Query Neighborhood Hits	137	Target Neighborhood Hits	284	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RFWD2_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.096460 (rank : 66)
Query Neighborhood Hits	137	Target Neighborhood Hits	518	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.096870 (rank : 65)
Query Neighborhood Hits	137	Target Neighborhood Hits	535	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RN139_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.079161 (rank : 95)
Query Neighborhood Hits	137	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN167_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.081664 (rank : 92)
Query Neighborhood Hits	137	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.081510 (rank : 93)
Query Neighborhood Hits	137	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF5_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.176403 (rank : 20)
Query Neighborhood Hits	137	Target Neighborhood Hits	206	Shared Neighborhood Hits	67
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.174402 (rank : 21)
Query Neighborhood Hits	137	Target Neighborhood Hits	206	Shared Neighborhood Hits	68
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI42_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.062848 (rank : 128)
Query Neighborhood Hits	137	Target Neighborhood Hits	316	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZMYM3_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.027277 (rank : 187)
Query Neighborhood Hits	137	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZMYM3_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.027162 (rank : 188)
Query Neighborhood Hits	137	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

TRAF7_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.039186 (rank : 183)
Query Neighborhood Hits	137	Target Neighborhood Hits	482	Shared Neighborhood Hits	49
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.038995 (rank : 184)
Query Neighborhood Hits	137	Target Neighborhood Hits	470	Shared Neighborhood Hits	49
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI17_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.083014 (rank : 86)
Query Neighborhood Hits	137	Target Neighborhood Hits	318	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI35_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.068978 (rank : 119)
Query Neighborhood Hits	137	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI62_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.070217 (rank : 112)
Query Neighborhood Hits	137	Target Neighborhood Hits	584	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.072705 (rank : 104)
Query Neighborhood Hits	137	Target Neighborhood Hits	478	Shared Neighborhood Hits	57
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM3_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.098937 (rank : 60)
Query Neighborhood Hits	137	Target Neighborhood Hits	357	Shared Neighborhood Hits	73
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM6_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.062732 (rank : 129)
Query Neighborhood Hits	137	Target Neighborhood Hits	451	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM7_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.068978 (rank : 118)
Query Neighborhood Hits	137	Target Neighborhood Hits	358	Shared Neighborhood Hits	53
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRM1_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.073212 (rank : 103)
Query Neighborhood Hits	137	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

BRE1B_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.041580 (rank : 182)
Query Neighborhood Hits	137	Target Neighborhood Hits	1040	Shared Neighborhood Hits	51
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.042797 (rank : 181)
Query Neighborhood Hits	137	Target Neighborhood Hits	970	Shared Neighborhood Hits	51
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

DTX3L_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.093350 (rank : 69)
Query Neighborhood Hits	137	Target Neighborhood Hits	187	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

NUPL2_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.069467 (rank : 116)
Query Neighborhood Hits	137	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

TOPRS_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.107595 (rank : 49)
Query Neighborhood Hits	137	Target Neighborhood Hits	286	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.120507 (rank : 40)
Query Neighborhood Hits	137	Target Neighborhood Hits	263	Shared Neighborhood Hits	60
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRIM3_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.094151 (rank : 67)
Query Neighborhood Hits	137	Target Neighborhood Hits	351	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

FBN1_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.004287 (rank : 204)
Query Neighborhood Hits	137	Target Neighborhood Hits	557	Shared Neighborhood Hits	5
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LNX2_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.070972 (rank : 109)
Query Neighborhood Hits	137	Target Neighborhood Hits	389	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RBM22_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.069860 (rank : 113)
Query Neighborhood Hits	137	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.069860 (rank : 114)
Query Neighborhood Hits	137	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RNF38_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.083277 (rank : 84)
Query Neighborhood Hits	137	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

TISB_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.150230 (rank : 26)
Query Neighborhood Hits	137	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISD_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.130393 (rank : 31)
Query Neighborhood Hits	137	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

TRI10_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.062140 (rank : 130)
Query Neighborhood Hits	137	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI12_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.097583 (rank : 63)
Query Neighborhood Hits	137	Target Neighborhood Hits	387	Shared Neighborhood Hits	59
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM7_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.069182 (rank : 117)
Query Neighborhood Hits	137	Target Neighborhood Hits	336	Shared Neighborhood Hits	52
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TTP_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.166958 (rank : 23)
Query Neighborhood Hits	137	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

BRE1A_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.026143 (rank : 190)
Query Neighborhood Hits	137	Target Neighborhood Hits	1071	Shared Neighborhood Hits	44
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.025687 (rank : 191)
Query Neighborhood Hits	137	Target Neighborhood Hits	1025	Shared Neighborhood Hits	41
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DUS3L_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.024331 (rank : 192)
Query Neighborhood Hits	137	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

FBN1_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.004049 (rank : 205)
Query Neighborhood Hits	137	Target Neighborhood Hits	563	Shared Neighborhood Hits	4
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

IRS2_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.011775 (rank : 198)
Query Neighborhood Hits	137	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

P_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.014794 (rank : 196)
Query Neighborhood Hits	137	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q04671, Q15211, Q15212, Q96EN1, Q9UMI5	Gene names	OCA2, P
Domain Architecture
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog).

SNPC4_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.009344 (rank : 200)
Query Neighborhood Hits	137	Target Neighborhood Hits	589	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TRI11_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.082215 (rank : 89)
Query Neighborhood Hits	137	Target Neighborhood Hits	316	Shared Neighborhood Hits	59
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.082708 (rank : 87)
Query Neighborhood Hits	137	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI30_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.090794 (rank : 73)
Query Neighborhood Hits	137	Target Neighborhood Hits	434	Shared Neighborhood Hits	60
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

ZGPAT_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.092480 (rank : 71)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

ZGPAT_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.079080 (rank : 96)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

ZSWM2_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.121884 (rank : 37)
Query Neighborhood Hits	137	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

LNX2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.063145 (rank : 127)
Query Neighborhood Hits	137	Target Neighborhood Hits	407	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PARC_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.036587 (rank : 185)
Query Neighborhood Hits	137	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PDXL2_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.012700 (rank : 197)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PP1RA_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.010738 (rank : 199)
Query Neighborhood Hits	137	Target Neighborhood Hits	180	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

RN139_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.057156 (rank : 144)
Query Neighborhood Hits	137	Target Neighborhood Hits	130	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

SEM3B_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.002938 (rank : 207)
Query Neighborhood Hits	137	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

TISB_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.145336 (rank : 28)
Query Neighborhood Hits	137	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

TRAF5_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.072344 (rank : 107)
Query Neighborhood Hits	137	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI42_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.052343 (rank : 169)
Query Neighborhood Hits	137	Target Neighborhood Hits	283	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

Z3H7A_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.019707 (rank : 194)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

BFAR_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.099663 (rank : 58)
Query Neighborhood Hits	137	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

DUS3L_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.052270 (rank : 170)
Query Neighborhood Hits	137	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

HAP1_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.007447 (rank : 201)
Query Neighborhood Hits	137	Target Neighborhood Hits	388	Shared Neighborhood Hits	7
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HRBL_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.006798 (rank : 202)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

LRFN2_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.000351 (rank : 208)
Query Neighborhood Hits	137	Target Neighborhood Hits	450	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

MAGE1_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.003748 (rank : 206)
Query Neighborhood Hits	137	Target Neighborhood Hits	1389	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MBN3_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.075343 (rank : 102)
Query Neighborhood Hits	137	Target Neighborhood Hits	34	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

PARC_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.026355 (rank : 189)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

RHG06_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.004637 (rank : 203)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RN165_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.070289 (rank : 111)
Query Neighborhood Hits	137	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN185_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.130572 (rank : 30)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	70
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.130244 (rank : 32)
Query Neighborhood Hits	137	Target Neighborhood Hits	211	Shared Neighborhood Hits	70
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF12_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.058588 (rank : 134)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

AMFR2_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.056911 (rank : 147)
Query Neighborhood Hits	137	Target Neighborhood Hits	219	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.057579 (rank : 142)
Query Neighborhood Hits	137	Target Neighborhood Hits	208	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

BFAR_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.092011 (rank : 72)
Query Neighborhood Hits	137	Target Neighborhood Hits	232	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.065387 (rank : 125)
Query Neighborhood Hits	137	Target Neighborhood Hits	381	Shared Neighborhood Hits	57
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.051936 (rank : 173)
Query Neighborhood Hits	137	Target Neighborhood Hits	436	Shared Neighborhood Hits	55
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CHFR_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.055732 (rank : 151)
Query Neighborhood Hits	137	Target Neighborhood Hits	255	Shared Neighborhood Hits	61
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.052199 (rank : 171)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

GOLI_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.051600 (rank : 175)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.051957 (rank : 172)
Query Neighborhood Hits	137	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

MBN3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.097763 (rank : 62)
Query Neighborhood Hits	137	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NUK0, Q5JXN8, Q5JXN9, Q5JXP4, Q6UDQ1, Q8TAD9, Q8TAF4, Q9H0Z7, Q9UF37	Gene names	MBNL3, CHCR, MBLX39, MBXL
Domain Architecture
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein HCHCR).

R113A_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.103702 (rank : 54)
Query Neighborhood Hits	137	Target Neighborhood Hits	177	Shared Neighborhood Hits	60
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.066047 (rank : 123)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RN122_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.055637 (rank : 153)
Query Neighborhood Hits	137	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.054269 (rank : 164)
Query Neighborhood Hits	137	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN125_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.072376 (rank : 106)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	53
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN166_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.058517 (rank : 135)
Query Neighborhood Hits	137	Target Neighborhood Hits	240	Shared Neighborhood Hits	57
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.058182 (rank : 136)
Query Neighborhood Hits	137	Target Neighborhood Hits	248	Shared Neighborhood Hits	57
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF12_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.053612 (rank : 167)
Query Neighborhood Hits	137	Target Neighborhood Hits	173	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF24_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.054725 (rank : 159)
Query Neighborhood Hits	137	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.055073 (rank : 157)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF41_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.090022 (rank : 75)
Query Neighborhood Hits	137	Target Neighborhood Hits	226	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.089987 (rank : 76)
Query Neighborhood Hits	137	Target Neighborhood Hits	224	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.081789 (rank : 91)
Query Neighborhood Hits	137	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.076026 (rank : 100)
Query Neighborhood Hits	137	Target Neighborhood Hits	212	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF6_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.050605 (rank : 178)
Query Neighborhood Hits	137	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF8_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.089515 (rank : 78)
Query Neighborhood Hits	137	Target Neighborhood Hits	622	Shared Neighborhood Hits	76
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.093824 (rank : 68)
Query Neighborhood Hits	137	Target Neighborhood Hits	618	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RO52_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.055441 (rank : 154)
Query Neighborhood Hits	137	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

RO52_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.056014 (rank : 149)
Query Neighborhood Hits	137	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

SMRA3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.051912 (rank : 174)
Query Neighborhood Hits	137	Target Neighborhood Hits	267	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TISD_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.124641 (rank : 35)
Query Neighborhood Hits	137	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

TRI10_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.058175 (rank : 137)
Query Neighborhood Hits	137	Target Neighborhood Hits	315	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI13_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.057453 (rank : 143)
Query Neighborhood Hits	137	Target Neighborhood Hits	274	Shared Neighborhood Hits	62
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.057591 (rank : 141)
Query Neighborhood Hits	137	Target Neighborhood Hits	282	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI15_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.050490 (rank : 179)
Query Neighborhood Hits	137	Target Neighborhood Hits	395	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.067842 (rank : 120)
Query Neighborhood Hits	137	Target Neighborhood Hits	620	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI25_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.055311 (rank : 155)
Query Neighborhood Hits	137	Target Neighborhood Hits	472	Shared Neighborhood Hits	57
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.063373 (rank : 126)
Query Neighborhood Hits	137	Target Neighborhood Hits	446	Shared Neighborhood Hits	60
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI26_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.059810 (rank : 131)
Query Neighborhood Hits	137	Target Neighborhood Hits	335	Shared Neighborhood Hits	59
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.058675 (rank : 133)
Query Neighborhood Hits	137	Target Neighborhood Hits	339	Shared Neighborhood Hits	59
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.056093 (rank : 148)
Query Neighborhood Hits	137	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.054660 (rank : 161)
Query Neighborhood Hits	137	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI31_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.075909 (rank : 101)
Query Neighborhood Hits	137	Target Neighborhood Hits	299	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.050429 (rank : 180)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	53
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI34_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.051407 (rank : 177)
Query Neighborhood Hits	137	Target Neighborhood Hits	416	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI35_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.066447 (rank : 122)
Query Neighborhood Hits	137	Target Neighborhood Hits	465	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.078589 (rank : 98)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	53
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.078671 (rank : 97)
Query Neighborhood Hits	137	Target Neighborhood Hits	316	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI38_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.077577 (rank : 99)
Query Neighborhood Hits	137	Target Neighborhood Hits	373	Shared Neighborhood Hits	55
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI40_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.117057 (rank : 43)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	58
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI43_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.056986 (rank : 146)
Query Neighborhood Hits	137	Target Neighborhood Hits	341	Shared Neighborhood Hits	53
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI50_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.058128 (rank : 138)
Query Neighborhood Hits	137	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.054668 (rank : 160)
Query Neighborhood Hits	137	Target Neighborhood Hits	326	Shared Neighborhood Hits	54
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI52_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.054527 (rank : 162)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI59_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.053355 (rank : 168)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.051443 (rank : 176)
Query Neighborhood Hits	137	Target Neighborhood Hits	292	Shared Neighborhood Hits	61
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI60_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.057924 (rank : 139)
Query Neighborhood Hits	137	Target Neighborhood Hits	357	Shared Neighborhood Hits	57
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI60_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.055991 (rank : 150)
Query Neighborhood Hits	137	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI68_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.054342 (rank : 163)
Query Neighborhood Hits	137	Target Neighborhood Hits	267	Shared Neighborhood Hits	51
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI73_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.055714 (rank : 152)
Query Neighborhood Hits	137	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.055132 (rank : 156)
Query Neighborhood Hits	137	Target Neighborhood Hits	249	Shared Neighborhood Hits	47
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM4_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.054143 (rank : 165)
Query Neighborhood Hits	137	Target Neighborhood Hits	321	Shared Neighborhood Hits	51
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM5_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.065718 (rank : 124)
Query Neighborhood Hits	137	Target Neighborhood Hits	424	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM6_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.058975 (rank : 132)
Query Neighborhood Hits	137	Target Neighborhood Hits	412	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

ZC11A_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.081448 (rank : 94)
Query Neighborhood Hits	137	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZC11A_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.072431 (rank : 105)
Query Neighborhood Hits	137	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZC3H3_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.173950 (rank : 22)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.165557 (rank : 24)
Query Neighborhood Hits	137	Target Neighborhood Hits	188	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZN179_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.057781 (rank : 140)
Query Neighborhood Hits	137	Target Neighborhood Hits	178	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN313_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.054776 (rank : 158)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.053717 (rank : 166)
Query Neighborhood Hits	137	Target Neighborhood Hits	273	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

MKRN3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	137
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MKRN3_HUMAN
NC score	0.976533 (rank : 2)	θ value	7.78761e-153 (rank : 2)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	96
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN4_HUMAN
NC score	0.960626 (rank : 3)	θ value	9.6755e-95 (rank : 5)
Query Neighborhood Hits	137	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MKRN1_HUMAN
NC score	0.952173 (rank : 4)	θ value	9.34977e-98 (rank : 4)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
NC score	0.951780 (rank : 5)	θ value	6.47494e-99 (rank : 3)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN2_HUMAN
NC score	0.915818 (rank : 6)	θ value	6.53529e-67 (rank : 6)
Query Neighborhood Hits	137	Target Neighborhood Hits	129	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
NC score	0.911630 (rank : 7)	θ value	3.24342e-66 (rank : 7)
Query Neighborhood Hits	137	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

ZC3H8_MOUSE
NC score	0.316115 (rank : 8)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	137	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

ZC3H8_HUMAN
NC score	0.298045 (rank : 9)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	137	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

ZC3H6_MOUSE
NC score	0.272865 (rank : 10)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	137	Target Neighborhood Hits	239	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CPSF4_HUMAN
NC score	0.268602 (rank : 11)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	137	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

CPSF4_MOUSE
NC score	0.267134 (rank : 12)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	137	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

ZC3H6_HUMAN
NC score	0.263803 (rank : 13)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	137	Target Neighborhood Hits	228	Shared Neighborhood Hits	36
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CS007_HUMAN
NC score	0.258077 (rank : 14)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	137	Target Neighborhood Hits	401	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
NC score	0.254766 (rank : 15)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	137	Target Neighborhood Hits	464	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

PEX10_HUMAN
NC score	0.210181 (rank : 16)	θ value	0.0431538 (rank : 15)
Query Neighborhood Hits	137	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN141_HUMAN
NC score	0.199947 (rank : 17)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	137	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.198464 (rank : 18)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	137	Target Neighborhood Hits	200	Shared Neighborhood Hits	65
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TTP_MOUSE
NC score	0.186522 (rank : 19)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	137	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

RNF5_HUMAN
NC score	0.176403 (rank : 20)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	137	Target Neighborhood Hits	206	Shared Neighborhood Hits	67
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.174402 (rank : 21)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	137	Target Neighborhood Hits	206	Shared Neighborhood Hits	68
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

ZC3H3_HUMAN
NC score	0.173950 (rank : 22)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

TTP_HUMAN
NC score	0.166958 (rank : 23)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	137	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

ZC3H3_MOUSE
NC score	0.165557 (rank : 24)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	137	Target Neighborhood Hits	188	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZSWM2_HUMAN
NC score	0.165390 (rank : 25)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	137	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

TISB_HUMAN
NC score	0.150230 (rank : 26)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	137	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

RNF19_MOUSE
NC score	0.145662 (rank : 27)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	137	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

TISB_MOUSE
NC score	0.145336 (rank : 28)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	137	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

RNF19_HUMAN
NC score	0.145209 (rank : 29)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RN185_HUMAN
NC score	0.130572 (rank : 30)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	70
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TISD_MOUSE
NC score	0.130393 (rank : 31)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	137	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

RN185_MOUSE
NC score	0.130244 (rank : 32)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	137	Target Neighborhood Hits	211	Shared Neighborhood Hits	70
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

APC11_MOUSE
NC score	0.129834 (rank : 33)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	137	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RN168_MOUSE
NC score	0.128079 (rank : 34)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	137	Target Neighborhood Hits	440	Shared Neighborhood Hits	51
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TISD_HUMAN
NC score	0.124641 (rank : 35)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	137	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

PAR12_HUMAN
NC score	0.123029 (rank : 36)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	137	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

ZSWM2_MOUSE
NC score	0.121884 (rank : 37)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	137	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN168_HUMAN
NC score	0.121425 (rank : 38)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	137	Target Neighborhood Hits	370	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI65_HUMAN
NC score	0.120683 (rank : 39)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	137	Target Neighborhood Hits	330	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TOPRS_MOUSE
NC score	0.120507 (rank : 40)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	137	Target Neighborhood Hits	263	Shared Neighborhood Hits	60
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI65_MOUSE
NC score	0.118363 (rank : 41)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	137	Target Neighborhood Hits	340	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

APC11_HUMAN
NC score	0.118055 (rank : 42)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	137	Target Neighborhood Hits	74	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

TRI40_HUMAN
NC score	0.117057 (rank : 43)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	58
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RN125_MOUSE
NC score	0.114626 (rank : 44)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	137	Target Neighborhood Hits	220	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RNF13_MOUSE
NC score	0.114190 (rank : 45)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	137	Target Neighborhood Hits	164	Shared Neighborhood Hits	42
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TRAIP_HUMAN
NC score	0.113098 (rank : 46)	θ value	0.00869519 (rank : 8)
Query Neighborhood Hits	137	Target Neighborhood Hits	780	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.110524 (rank : 47)	θ value	0.00869519 (rank : 9)
Query Neighborhood Hits	137	Target Neighborhood Hits	745	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RAD18_HUMAN
NC score	0.110227 (rank : 48)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	137	Target Neighborhood Hits	284	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TOPRS_HUMAN
NC score	0.107595 (rank : 49)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	137	Target Neighborhood Hits	286	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

PAR12_MOUSE
NC score	0.106837 (rank : 50)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	137	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

TRIM2_HUMAN
NC score	0.106687 (rank : 51)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	137	Target Neighborhood Hits	330	Shared Neighborhood Hits	72
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.106422 (rank : 52)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	137	Target Neighborhood Hits	331	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RNF13_HUMAN
NC score	0.105813 (rank : 53)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	137	Target Neighborhood Hits	147	Shared Neighborhood Hits	39
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

R113A_HUMAN
NC score	0.103702 (rank : 54)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	137	Target Neighborhood Hits	177	Shared Neighborhood Hits	60
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RAD18_MOUSE
NC score	0.102859 (rank : 55)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRI22_HUMAN
NC score	0.102756 (rank : 56)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	137	Target Neighborhood Hits	396	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

BRAP_MOUSE
NC score	0.100138 (rank : 57)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	137	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BFAR_HUMAN
NC score	0.099663 (rank : 58)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	137	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

IBRD3_HUMAN
NC score	0.099300 (rank : 59)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	137	Target Neighborhood Hits	70	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

TRIM3_HUMAN
NC score	0.098937 (rank : 60)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	137	Target Neighborhood Hits	357	Shared Neighborhood Hits	73
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

RNF38_HUMAN
NC score	0.098217 (rank : 61)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	137	Target Neighborhood Hits	155	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

MBN3_HUMAN
NC score	0.097763 (rank : 62)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	137	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NUK0, Q5JXN8, Q5JXN9, Q5JXP4, Q6UDQ1, Q8TAD9, Q8TAF4, Q9H0Z7, Q9UF37	Gene names	MBNL3, CHCR, MBLX39, MBXL
Domain Architecture
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein HCHCR).

TRI12_MOUSE
NC score	0.097583 (rank : 63)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	137	Target Neighborhood Hits	387	Shared Neighborhood Hits	59
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

ZC3H5_MOUSE
NC score	0.097035 (rank : 64)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	137	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

RFWD2_MOUSE
NC score	0.096870 (rank : 65)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	137	Target Neighborhood Hits	535	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.096460 (rank : 66)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	137	Target Neighborhood Hits	518	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRIM3_MOUSE
NC score	0.094151 (rank : 67)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	137	Target Neighborhood Hits	351	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RNF8_MOUSE
NC score	0.093824 (rank : 68)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	137	Target Neighborhood Hits	618	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

DTX3L_HUMAN
NC score	0.093350 (rank : 69)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	137	Target Neighborhood Hits	187	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

MYCB2_MOUSE
NC score	0.092574 (rank : 70)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ZGPAT_HUMAN
NC score	0.092480 (rank : 71)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

BFAR_MOUSE
NC score	0.092011 (rank : 72)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	137	Target Neighborhood Hits	232	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI30_MOUSE
NC score	0.090794 (rank : 73)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	137	Target Neighborhood Hits	434	Shared Neighborhood Hits	60
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

MBNL_HUMAN
NC score	0.090588 (rank : 74)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	137	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR56, O43311, O43797	Gene names	MBNL1, EXP, KIAA0428, MBNL
Domain Architecture
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

RNF41_HUMAN
NC score	0.090022 (rank : 75)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	137	Target Neighborhood Hits	226	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.089987 (rank : 76)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	137	Target Neighborhood Hits	224	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

BRAP_HUMAN
NC score	0.089519 (rank : 77)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	137	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RNF8_HUMAN
NC score	0.089515 (rank : 78)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	137	Target Neighborhood Hits	622	Shared Neighborhood Hits	76
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI39_HUMAN
NC score	0.089232 (rank : 79)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	137	Target Neighborhood Hits	693	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
NC score	0.088165 (rank : 80)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	137	Target Neighborhood Hits	691	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RAPSN_HUMAN
NC score	0.087742 (rank : 81)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

MBNL_MOUSE
NC score	0.087158 (rank : 82)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	137	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JKP5	Gene names	Mbnl1, Exp, Mbnl
Domain Architecture	No domain graphic available
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

MYCB2_HUMAN
NC score	0.086900 (rank : 83)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	137	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RNF38_MOUSE
NC score	0.083277 (rank : 84)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	137	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

NUPL2_HUMAN
NC score	0.083179 (rank : 85)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	137	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	O15504, Q49AE7, Q9BS49	Gene names	NUPL2, CG1
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1) (hCG1) (NUP42 homolog).

TRI17_HUMAN
NC score	0.083014 (rank : 86)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	137	Target Neighborhood Hits	318	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI11_MOUSE
NC score	0.082708 (rank : 87)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	137	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

ZC3H5_HUMAN
NC score	0.082609 (rank : 88)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	137	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

TRI11_HUMAN
NC score	0.082215 (rank : 89)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	137	Target Neighborhood Hits	316	Shared Neighborhood Hits	59
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

RAPSN_MOUSE
NC score	0.082119 (rank : 90)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	25
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RNF4_HUMAN
NC score	0.081789 (rank : 91)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	137	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RN167_HUMAN
NC score	0.081664 (rank : 92)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	137	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
NC score	0.081510 (rank : 93)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	137	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

ZC11A_HUMAN
NC score	0.081448 (rank : 94)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	137	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

RN139_MOUSE
NC score	0.079161 (rank : 95)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	137	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

ZGPAT_MOUSE
NC score	0.079080 (rank : 96)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

TRI37_MOUSE
NC score	0.078671 (rank : 97)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	137	Target Neighborhood Hits	316	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.078589 (rank : 98)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	53
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI38_HUMAN
NC score	0.077577 (rank : 99)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	137	Target Neighborhood Hits	373	Shared Neighborhood Hits	55
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

RNF4_MOUSE
NC score	0.076026 (rank : 100)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	137	Target Neighborhood Hits	212	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI31_HUMAN
NC score	0.075909 (rank : 101)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	137	Target Neighborhood Hits	299	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

MBN3_MOUSE
NC score	0.075343 (rank : 102)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	137	Target Neighborhood Hits	34	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

TRM1_HUMAN
NC score	0.073212 (rank : 103)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	137	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

TRI62_MOUSE
NC score	0.072705 (rank : 104)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	137	Target Neighborhood Hits	478	Shared Neighborhood Hits	57
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

ZC11A_MOUSE
NC score	0.072431 (rank : 105)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	137	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

RN125_HUMAN
NC score	0.072376 (rank : 106)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	53
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRAF5_MOUSE
NC score	0.072344 (rank : 107)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	137	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

DHX57_HUMAN
NC score	0.071118 (rank : 108)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	137	Target Neighborhood Hits	109	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

LNX2_HUMAN
NC score	0.070972 (rank : 109)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	137	Target Neighborhood Hits	389	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TRI68_MOUSE
NC score	0.070526 (rank : 110)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	137	Target Neighborhood Hits	356	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RN165_HUMAN
NC score	0.070289 (rank : 111)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	137	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

TRI62_HUMAN
NC score	0.070217 (rank : 112)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	137	Target Neighborhood Hits	584	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RBM22_HUMAN
NC score	0.069860 (rank : 113)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	137	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
NC score	0.069860 (rank : 114)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	137	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

LNX1_HUMAN
NC score	0.069489 (rank : 115)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	137	Target Neighborhood Hits	379	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

NUPL2_MOUSE
NC score	0.069467 (rank : 116)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	137	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

TRIM7_HUMAN
NC score	0.069182 (rank : 117)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	137	Target Neighborhood Hits	336	Shared Neighborhood Hits	52
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
NC score	0.068978 (rank : 118)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	137	Target Neighborhood Hits	358	Shared Neighborhood Hits	53
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI35_HUMAN
NC score	0.068978 (rank : 119)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	137	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI17_MOUSE
NC score	0.067842 (rank : 120)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	137	Target Neighborhood Hits	620	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

DHX57_MOUSE
NC score	0.067224 (rank : 121)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	137	Target Neighborhood Hits	125	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

TRI35_MOUSE
NC score	0.066447 (rank : 122)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	137	Target Neighborhood Hits	465	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

R113B_HUMAN
NC score	0.066047 (rank : 123)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRIM5_HUMAN
NC score	0.065718 (rank : 124)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	137	Target Neighborhood Hits	424	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

BRCA1_HUMAN
NC score	0.065387 (rank : 125)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	137	Target Neighborhood Hits	381	Shared Neighborhood Hits	57
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI25_MOUSE
NC score	0.063373 (rank : 126)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	137	Target Neighborhood Hits	446	Shared Neighborhood Hits	60
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

LNX2_MOUSE
NC score	0.063145 (rank : 127)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	137	Target Neighborhood Hits	407	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TRI42_MOUSE
NC score	0.062848 (rank : 128)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	137	Target Neighborhood Hits	316	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRIM6_MOUSE
NC score	0.062732 (rank : 129)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	137	Target Neighborhood Hits	451	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI10_MOUSE
NC score	0.062140 (rank : 130)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	137	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI26_HUMAN
NC score	0.059810 (rank : 131)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	137	Target Neighborhood Hits	335	Shared Neighborhood Hits	59
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRIM6_HUMAN
NC score	0.058975 (rank : 132)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	137	Target Neighborhood Hits	412	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI26_MOUSE
NC score	0.058675 (rank : 133)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	137	Target Neighborhood Hits	339	Shared Neighborhood Hits	59
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

RNF12_MOUSE
NC score	0.058588 (rank : 134)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RN166_HUMAN
NC score	0.058517 (rank : 135)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	137	Target Neighborhood Hits	240	Shared Neighborhood Hits	57
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.058182 (rank : 136)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	137	Target Neighborhood Hits	248	Shared Neighborhood Hits	57
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI10_HUMAN
NC score	0.058175 (rank : 137)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	137	Target Neighborhood Hits	315	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI50_HUMAN
NC score	0.058128 (rank : 138)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	137	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI60_HUMAN
NC score	0.057924 (rank : 139)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	137	Target Neighborhood Hits	357	Shared Neighborhood Hits	57
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

ZN179_HUMAN
NC score	0.057781 (rank : 140)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	137	Target Neighborhood Hits	178	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI13_MOUSE
NC score	0.057591 (rank : 141)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	137	Target Neighborhood Hits	282	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

AMFR_MOUSE
NC score	0.057579 (rank : 142)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	137	Target Neighborhood Hits	208	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TRI13_HUMAN
NC score	0.057453 (rank : 143)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	137	Target Neighborhood Hits	274	Shared Neighborhood Hits	62
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

RN139_HUMAN
NC score	0.057156 (rank : 144)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	137	Target Neighborhood Hits	130	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

NFX1_HUMAN
NC score	0.057150 (rank : 145)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	137	Target Neighborhood Hits	405	Shared Neighborhood Hits	15
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TRI43_HUMAN
NC score	0.056986 (rank : 146)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	137	Target Neighborhood Hits	341	Shared Neighborhood Hits	53
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

AMFR2_HUMAN
NC score	0.056911 (rank : 147)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	137	Target Neighborhood Hits	219	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

TRI27_HUMAN
NC score	0.056093 (rank : 148)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	137	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

RO52_MOUSE
NC score	0.056014 (rank : 149)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	137	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI60_MOUSE
NC score	0.055991 (rank : 150)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	137	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

CHFR_HUMAN
NC score	0.055732 (rank : 151)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	137	Target Neighborhood Hits	255	Shared Neighborhood Hits	61
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI73_HUMAN
NC score	0.055714 (rank : 152)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	137	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

RN122_HUMAN
NC score	0.055637 (rank : 153)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	137	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RO52_HUMAN
NC score	0.055441 (rank : 154)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	137	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI25_HUMAN
NC score	0.055311 (rank : 155)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	137	Target Neighborhood Hits	472	Shared Neighborhood Hits	57
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI74_HUMAN
NC score	0.055132 (rank : 156)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	137	Target Neighborhood Hits	249	Shared Neighborhood Hits	47
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

RNF24_MOUSE
NC score	0.055073 (rank : 157)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

ZN313_HUMAN
NC score	0.054776 (rank : 158)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RNF24_HUMAN
NC score	0.054725 (rank : 159)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	137	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

TRI50_MOUSE
NC score	0.054668 (rank : 160)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	137	Target Neighborhood Hits	326	Shared Neighborhood Hits	54
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI27_MOUSE
NC score	0.054660 (rank : 161)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	137	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI52_HUMAN
NC score	0.054527 (rank : 162)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI68_HUMAN
NC score	0.054342 (rank : 163)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	137	Target Neighborhood Hits	267	Shared Neighborhood Hits	51
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RN122_MOUSE
NC score	0.054269 (rank : 164)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	137	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

TRIM4_HUMAN
NC score	0.054143 (rank : 165)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	137	Target Neighborhood Hits	321	Shared Neighborhood Hits	51
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

ZN313_MOUSE
NC score	0.053717 (rank : 166)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	137	Target Neighborhood Hits	273	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RNF12_HUMAN
NC score	0.053612 (rank : 167)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	137	Target Neighborhood Hits	173	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

TRI59_HUMAN
NC score	0.053355 (rank : 168)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI42_HUMAN
NC score	0.052343 (rank : 169)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	137	Target Neighborhood Hits	283	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

DUS3L_HUMAN
NC score	0.052270 (rank : 170)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	137	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

CHFR_MOUSE
NC score	0.052199 (rank : 171)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

GOLI_MOUSE
NC score	0.051957 (rank : 172)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	137	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

BRCA1_MOUSE
NC score	0.051936 (rank : 173)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	137	Target Neighborhood Hits	436	Shared Neighborhood Hits	55
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

SMRA3_MOUSE
NC score	0.051912 (rank : 174)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	137	Target Neighborhood Hits	267	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

GOLI_HUMAN
NC score	0.051600 (rank : 175)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

TRI59_MOUSE
NC score	0.051443 (rank : 176)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	137	Target Neighborhood Hits	292	Shared Neighborhood Hits	61
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI34_HUMAN
NC score	0.051407 (rank : 177)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	137	Target Neighborhood Hits	416	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RNF6_HUMAN
NC score	0.050605 (rank : 178)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	137	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

TRI15_HUMAN
NC score	0.050490 (rank : 179)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	137	Target Neighborhood Hits	395	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI32_HUMAN
NC score	0.050429 (rank : 180)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	53
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

BRE1B_MOUSE
NC score	0.042797 (rank : 181)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	137	Target Neighborhood Hits	970	Shared Neighborhood Hits	51
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.041580 (rank : 182)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	137	Target Neighborhood Hits	1040	Shared Neighborhood Hits	51
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TRAF7_HUMAN
NC score	0.039186 (rank : 183)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	137	Target Neighborhood Hits	482	Shared Neighborhood Hits	49
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
NC score	0.038995 (rank : 184)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	137	Target Neighborhood Hits	470	Shared Neighborhood Hits	49
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

PARC_HUMAN
NC score	0.036587 (rank : 185)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	137	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

TACC3_HUMAN
NC score	0.032342 (rank : 186)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	137	Target Neighborhood Hits	779	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ZMYM3_HUMAN
NC score	0.027277 (rank : 187)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	137	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZMYM3_MOUSE
NC score	0.027162 (rank : 188)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	137	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

PARC_MOUSE
NC score	0.026355 (rank : 189)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

BRE1A_HUMAN
NC score	0.026143 (rank : 190)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	137	Target Neighborhood Hits	1071	Shared Neighborhood Hits	44
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
NC score	0.025687 (rank : 191)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	137	Target Neighborhood Hits	1025	Shared Neighborhood Hits	41
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DUS3L_MOUSE
NC score	0.024331 (rank : 192)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	137	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

TAU_MOUSE
NC score	0.019720 (rank : 193)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	137	Target Neighborhood Hits	502	Shared Neighborhood Hits	10
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

Z3H7A_HUMAN
NC score	0.019707 (rank : 194)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

PDZD2_HUMAN
NC score	0.018639 (rank : 195)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	137	Target Neighborhood Hits	772	Shared Neighborhood Hits	13
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

P_HUMAN
NC score	0.014794 (rank : 196)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	137	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q04671, Q15211, Q15212, Q96EN1, Q9UMI5	Gene names	OCA2, P
Domain Architecture
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog).

PDXL2_MOUSE
NC score	0.012700 (rank : 197)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

IRS2_HUMAN
NC score	0.011775 (rank : 198)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	137	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PP1RA_HUMAN
NC score	0.010738 (rank : 199)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	137	Target Neighborhood Hits	180	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

SNPC4_HUMAN
NC score	0.009344 (rank : 200)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	137	Target Neighborhood Hits	589	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

HAP1_MOUSE
NC score	0.007447 (rank : 201)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	137	Target Neighborhood Hits	388	Shared Neighborhood Hits	7
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HRBL_HUMAN
NC score	0.006798 (rank : 202)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

RHG06_HUMAN
NC score	0.004637 (rank : 203)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

FBN1_HUMAN
NC score	0.004287 (rank : 204)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	137	Target Neighborhood Hits	557	Shared Neighborhood Hits	5
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
NC score	0.004049 (rank : 205)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	137	Target Neighborhood Hits	563	Shared Neighborhood Hits	4
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

MAGE1_HUMAN
NC score	0.003748 (rank : 206)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	137	Target Neighborhood Hits	1389	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SEM3B_HUMAN
NC score	0.002938 (rank : 207)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	137	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

LRFN2_MOUSE
NC score	0.000351 (rank : 208)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	137	Target Neighborhood Hits	450	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.