Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PARC_MOUSE

For an explanation of this page, click here

PARC_MOUSE
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CUL7_HUMAN
θ value	0 (rank : 1)	NC score	0.811550 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

PARC_HUMAN
θ value	0 (rank : 2)	NC score	0.986191 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

ARI2_HUMAN
θ value	2.19075e-38 (rank : 4)	NC score	0.688157 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	2.86122e-38 (rank : 5)	NC score	0.687702 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	106	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI1_HUMAN
θ value	1.79631e-32 (rank : 6)	NC score	0.672716 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	1.79631e-32 (rank : 7)	NC score	0.672586 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

HECD3_HUMAN
θ value	1.74391e-19 (rank : 8)	NC score	0.363711 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	1.74391e-19 (rank : 9)	NC score	0.363515 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_HUMAN
θ value	1.74391e-19 (rank : 10)	NC score	0.267482 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	163	Shared Neighborhood Hits	12
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	1.24977e-17 (rank : 11)	NC score	0.260948 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

RNF14_MOUSE
θ value	2.13179e-17 (rank : 12)	NC score	0.583514 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF14_HUMAN
θ value	1.058e-16 (rank : 13)	NC score	0.581319 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

IBRD3_HUMAN
θ value	1.68911e-14 (rank : 14)	NC score	0.552918 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	4.91457e-14 (rank : 15)	NC score	0.521893 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	4.91457e-14 (rank : 16)	NC score	0.522893 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

UB7I4_MOUSE
θ value	4.91457e-14 (rank : 17)	NC score	0.562090 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
θ value	2.43908e-13 (rank : 18)	NC score	0.558311 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD2_MOUSE
θ value	2.28291e-11 (rank : 19)	NC score	0.542338 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

PRKN2_MOUSE
θ value	3.89403e-11 (rank : 20)	NC score	0.494143 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
θ value	1.9326e-10 (rank : 21)	NC score	0.492443 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

RNF31_HUMAN
θ value	2.52405e-10 (rank : 22)	NC score	0.429151 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	110	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UB7I3_HUMAN
θ value	5.62301e-10 (rank : 23)	NC score	0.445833 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	136	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	5.62301e-10 (rank : 24)	NC score	0.447876 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RNF31_MOUSE
θ value	1.63604e-09 (rank : 25)	NC score	0.424143 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

IBRD2_HUMAN
θ value	1.38499e-08 (rank : 26)	NC score	0.528466 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD1_HUMAN
θ value	2.61198e-07 (rank : 27)	NC score	0.526432 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

CUL4A_HUMAN
θ value	0.00020696 (rank : 28)	NC score	0.097661 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

APC10_HUMAN
θ value	0.000270298 (rank : 29)	NC score	0.289799 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UM13, Q2V500, Q9UG51, Q9Y5R0	Gene names	ANAPC10, APC10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

APC10_MOUSE
θ value	0.000270298 (rank : 30)	NC score	0.287927 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2H6, Q9CW24	Gene names	Anapc10, Apc10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

CUL4A_MOUSE
θ value	0.00102713 (rank : 31)	NC score	0.096776 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4B_HUMAN
θ value	0.00228821 (rank : 32)	NC score	0.098267 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

PHLB3_HUMAN
θ value	0.0252991 (rank : 33)	NC score	0.047120 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	304	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

NOTC1_MOUSE
θ value	0.0563607 (rank : 34)	NC score	0.013883 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	916	Shared Neighborhood Hits	11
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ABLM1_MOUSE
θ value	0.0736092 (rank : 35)	NC score	0.026443 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	356	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

ABLM1_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.022744 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

FBN3_HUMAN
θ value	0.0961366 (rank : 37)	NC score	0.021020 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	10
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

TRIM9_HUMAN
θ value	0.163984 (rank : 38)	NC score	0.050320 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

SEC63_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.041377 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	601	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

ALS2_HUMAN
θ value	0.279714 (rank : 40)	NC score	0.053439 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

PDE9A_MOUSE
θ value	0.279714 (rank : 41)	NC score	0.034391 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

SEC63_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.033504 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	586	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SRRM2_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.026066 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CD177_HUMAN
θ value	0.365318 (rank : 44)	NC score	0.057780 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N6Q3, Q711Q2, Q8NCV9, Q96QH1, Q9HDA5	Gene names	CD177, NB1, PRV1
Domain Architecture	No domain graphic available
Description	CD177 antigen precursor (Polycythemia rubra vera protein 1) (PRV-1) (NB1 glycoprotein) (NB1 GP) (Human neutrophil alloantigen 2a) (HNA- 2a).

PEX10_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.067321 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	255	Shared Neighborhood Hits	25
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PRA12_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.015518 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

ERF_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.020756 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
θ value	0.62314 (rank : 48)	NC score	0.020832 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

LEO1_MOUSE
θ value	0.62314 (rank : 49)	NC score	0.022451 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	946	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NSBP1_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.024338 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	681	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PDE9A_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.030997 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PEG3_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.002609 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	1101	Shared Neighborhood Hits	14
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TTC1_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.017423 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	417	Shared Neighborhood Hits	8
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

IF4G1_MOUSE
θ value	0.813845 (rank : 54)	NC score	0.017149 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IWS1_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.020094 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	1241	Shared Neighborhood Hits	21
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRIM9_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.044797 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

UB7I1_MOUSE
θ value	0.813845 (rank : 57)	NC score	0.289986 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

ZEP1_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.014843 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	1036	Shared Neighborhood Hits	15
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

LEO1_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.021844 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

UB7I1_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.292388 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

BPTF_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.014064 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	786	Shared Neighborhood Hits	20
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRE1A_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.010912 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	1025	Shared Neighborhood Hits	30
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

TOPRS_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.065649 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	286	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	1.38821 (rank : 64)	NC score	0.066407 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	263	Shared Neighborhood Hits	27
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ADA18_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.011644 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

BCL9_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.011608 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	1008	Shared Neighborhood Hits	11
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CO7A1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.004659 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	807	Shared Neighborhood Hits	9
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

SAMD4_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.028576 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

TRI37_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.023402 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

CNOT4_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.045833 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.043702 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

NOTC1_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.010385 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	906	Shared Neighborhood Hits	11
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RNF5_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.046491 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

CCD21_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.003434 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

DTBP1_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.019627 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

DTBP1_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.019783 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

FBN2_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.012114 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	549	Shared Neighborhood Hits	8
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FEZ1_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.013436 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	Q99689, O00679, O00728, Q6IBI7	Gene names	FEZ1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

SAMD4_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.025398 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

BSCL2_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.014995 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

CC47_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.013313 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CF049_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.017306 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q2TBC4, Q5T3D4, Q9NSV1	Gene names	C6orf49
Domain Architecture	No domain graphic available
Description	Protein C6orf49.

FLT3_MOUSE
θ value	5.27518 (rank : 83)	NC score	-0.001891 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	847	Shared Neighborhood Hits	2
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

MKRN3_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.030318 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

PCSK5_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.010764 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	613	Shared Neighborhood Hits	13
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RO52_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.007446 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TE2IP_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.014400 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

DMXL1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.006225 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	259	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

GOLI_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.034149 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	13
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.026002 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

PLXA4_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.006055 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

RBCC1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.002601 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	1023	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RNF5_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.042727 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

FBXL7_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.005282 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

GRID1_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.002656 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

JIP3_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.002998 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	1039	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MKRN3_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.026355 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MYCB2_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.039918 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	390	Shared Neighborhood Hits	17
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.039779 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYH3_HUMAN
θ value	8.99809 (rank : 100)	NC score	-0.001527 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	1660	Shared Neighborhood Hits	15
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PRGC2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.007216 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RAG2_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.009519 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

RN152_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.044008 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.044020 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN185_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.041719 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.041160 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

SALL2_HUMAN
θ value	8.99809 (rank : 107)	NC score	-0.001355 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	835	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

SYNE1_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.000553 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	1484	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TP53B_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.011983 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	413	Shared Neighborhood Hits	12
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRI27_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.009516 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	273	Shared Neighborhood Hits	24
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.008877 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	23
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI36_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.019647 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

WNK2_HUMAN
θ value	8.99809 (rank : 113)	NC score	-0.003179 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	1407	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZAN_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.010956 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	808	Shared Neighborhood Hits	14
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CUL1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.060622 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.060617 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL3_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.055196 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.055230 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

EDD1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.055161 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.055493 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD2_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.050762 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.051098 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HERC3_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.054948 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.056205 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HUWE1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.055206 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.055054 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

RCC1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.050808 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC2_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.051142 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.050702 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

SRGEF_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.051013 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRGEF_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.051039 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

TRIPC_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.057109 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	319	Shared Neighborhood Hits	7
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.052274 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3C_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.054139 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.053806 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

Hits sorted by NC score

PARC_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PARC_HUMAN
NC score	0.986191 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

CUL7_HUMAN
NC score	0.811550 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

ARI2_HUMAN
NC score	0.688157 (rank : 4)	θ value	2.19075e-38 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.687702 (rank : 5)	θ value	2.86122e-38 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	106	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI1_HUMAN
NC score	0.672716 (rank : 6)	θ value	1.79631e-32 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.672586 (rank : 7)	θ value	1.79631e-32 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

RNF14_MOUSE
NC score	0.583514 (rank : 8)	θ value	2.13179e-17 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF14_HUMAN
NC score	0.581319 (rank : 9)	θ value	1.058e-16 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

UB7I4_MOUSE
NC score	0.562090 (rank : 10)	θ value	4.91457e-14 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
NC score	0.558311 (rank : 11)	θ value	2.43908e-13 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD3_HUMAN
NC score	0.552918 (rank : 12)	θ value	1.68911e-14 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

IBRD2_MOUSE
NC score	0.542338 (rank : 13)	θ value	2.28291e-11 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
NC score	0.528466 (rank : 14)	θ value	1.38499e-08 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD1_HUMAN
NC score	0.526432 (rank : 15)	θ value	2.61198e-07 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

RNF19_MOUSE
NC score	0.522893 (rank : 16)	θ value	4.91457e-14 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.521893 (rank : 17)	θ value	4.91457e-14 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

PRKN2_MOUSE
NC score	0.494143 (rank : 18)	θ value	3.89403e-11 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
NC score	0.492443 (rank : 19)	θ value	1.9326e-10 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

UB7I3_MOUSE
NC score	0.447876 (rank : 20)	θ value	5.62301e-10 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UB7I3_HUMAN
NC score	0.445833 (rank : 21)	θ value	5.62301e-10 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	136	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RNF31_HUMAN
NC score	0.429151 (rank : 22)	θ value	2.52405e-10 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	110	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.424143 (rank : 23)	θ value	1.63604e-09 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

HECD3_HUMAN
NC score	0.363711 (rank : 24)	θ value	1.74391e-19 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
NC score	0.363515 (rank : 25)	θ value	1.74391e-19 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

UB7I1_HUMAN
NC score	0.292388 (rank : 26)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
NC score	0.289986 (rank : 27)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

APC10_HUMAN
NC score	0.289799 (rank : 28)	θ value	0.000270298 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UM13, Q2V500, Q9UG51, Q9Y5R0	Gene names	ANAPC10, APC10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

APC10_MOUSE
NC score	0.287927 (rank : 29)	θ value	0.000270298 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2H6, Q9CW24	Gene names	Anapc10, Apc10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

HERC2_HUMAN
NC score	0.267482 (rank : 30)	θ value	1.74391e-19 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	163	Shared Neighborhood Hits	12
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
NC score	0.260948 (rank : 31)	θ value	1.24977e-17 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

CUL4B_HUMAN
NC score	0.098267 (rank : 32)	θ value	0.00228821 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL4A_HUMAN
NC score	0.097661 (rank : 33)	θ value	0.00020696 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

CUL4A_MOUSE
NC score	0.096776 (rank : 34)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

PEX10_HUMAN
NC score	0.067321 (rank : 35)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	255	Shared Neighborhood Hits	25
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TOPRS_MOUSE
NC score	0.066407 (rank : 36)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	263	Shared Neighborhood Hits	27
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.065649 (rank : 37)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	286	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CUL1_HUMAN
NC score	0.060622 (rank : 38)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
NC score	0.060617 (rank : 39)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CD177_HUMAN
NC score	0.057780 (rank : 40)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N6Q3, Q711Q2, Q8NCV9, Q96QH1, Q9HDA5	Gene names	CD177, NB1, PRV1
Domain Architecture	No domain graphic available
Description	CD177 antigen precursor (Polycythemia rubra vera protein 1) (PRV-1) (NB1 glycoprotein) (NB1 GP) (Human neutrophil alloantigen 2a) (HNA- 2a).

TRIPC_HUMAN
NC score	0.057109 (rank : 41)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	319	Shared Neighborhood Hits	7
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HERC5_HUMAN
NC score	0.056205 (rank : 42)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

EDD1_MOUSE
NC score	0.055493 (rank : 43)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

CUL3_MOUSE
NC score	0.055230 (rank : 44)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

HUWE1_HUMAN
NC score	0.055206 (rank : 45)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

CUL3_HUMAN
NC score	0.055196 (rank : 46)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

EDD1_HUMAN
NC score	0.055161 (rank : 47)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HUWE1_MOUSE
NC score	0.055054 (rank : 48)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HERC3_HUMAN
NC score	0.054948 (rank : 49)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

UBE3C_HUMAN
NC score	0.054139 (rank : 50)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.053806 (rank : 51)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

ALS2_HUMAN
NC score	0.053439 (rank : 52)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

UBE3A_HUMAN
NC score	0.052274 (rank : 53)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

RCC2_HUMAN
NC score	0.051142 (rank : 54)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

HECD2_MOUSE
NC score	0.051098 (rank : 55)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

SRGEF_MOUSE
NC score	0.051039 (rank : 56)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRGEF_HUMAN
NC score	0.051013 (rank : 57)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

RCC1_HUMAN
NC score	0.050808 (rank : 58)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

HECD2_HUMAN
NC score	0.050762 (rank : 59)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

RCC2_MOUSE
NC score	0.050702 (rank : 60)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

TRIM9_HUMAN
NC score	0.050320 (rank : 61)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

PHLB3_HUMAN
NC score	0.047120 (rank : 62)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	304	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

RNF5_MOUSE
NC score	0.046491 (rank : 63)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

CNOT4_HUMAN
NC score	0.045833 (rank : 64)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

TRIM9_MOUSE
NC score	0.044797 (rank : 65)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RN152_MOUSE
NC score	0.044020 (rank : 66)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN152_HUMAN
NC score	0.044008 (rank : 67)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

CNOT4_MOUSE
NC score	0.043702 (rank : 68)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RNF5_HUMAN
NC score	0.042727 (rank : 69)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RN185_HUMAN
NC score	0.041719 (rank : 70)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

SEC63_MOUSE
NC score	0.041377 (rank : 71)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	601	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

RN185_MOUSE
NC score	0.041160 (rank : 72)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

MYCB2_HUMAN
NC score	0.039918 (rank : 73)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	390	Shared Neighborhood Hits	17
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
NC score	0.039779 (rank : 74)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PDE9A_MOUSE
NC score	0.034391 (rank : 75)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

GOLI_HUMAN
NC score	0.034149 (rank : 76)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	13
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

SEC63_HUMAN
NC score	0.033504 (rank : 77)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	586	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

PDE9A_HUMAN
NC score	0.030997 (rank : 78)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

MKRN3_HUMAN
NC score	0.030318 (rank : 79)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

SAMD4_MOUSE
NC score	0.028576 (rank : 80)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

ABLM1_MOUSE
NC score	0.026443 (rank : 81)	θ value	0.0736092 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	356	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

MKRN3_MOUSE
NC score	0.026355 (rank : 82)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

SRRM2_HUMAN
NC score	0.026066 (rank : 83)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

GOLI_MOUSE
NC score	0.026002 (rank : 84)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

SAMD4_HUMAN
NC score	0.025398 (rank : 85)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

NSBP1_MOUSE
NC score	0.024338 (rank : 86)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	681	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

TRI37_MOUSE
NC score	0.023402 (rank : 87)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

ABLM1_HUMAN
NC score	0.022744 (rank : 88)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

LEO1_MOUSE
NC score	0.022451 (rank : 89)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	946	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.021844 (rank : 90)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

FBN3_HUMAN
NC score	0.021020 (rank : 91)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	10
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ERF_MOUSE
NC score	0.020832 (rank : 92)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

ERF_HUMAN
NC score	0.020756 (rank : 93)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

IWS1_HUMAN
NC score	0.020094 (rank : 94)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	1241	Shared Neighborhood Hits	21
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DTBP1_MOUSE
NC score	0.019783 (rank : 95)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

TRI36_MOUSE
NC score	0.019647 (rank : 96)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

DTBP1_HUMAN
NC score	0.019627 (rank : 97)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

TTC1_HUMAN
NC score	0.017423 (rank : 98)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	417	Shared Neighborhood Hits	8
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

CF049_HUMAN
NC score	0.017306 (rank : 99)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q2TBC4, Q5T3D4, Q9NSV1	Gene names	C6orf49
Domain Architecture	No domain graphic available
Description	Protein C6orf49.

IF4G1_MOUSE
NC score	0.017149 (rank : 100)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PRA12_HUMAN
NC score	0.015518 (rank : 101)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

BSCL2_MOUSE
NC score	0.014995 (rank : 102)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

ZEP1_HUMAN
NC score	0.014843 (rank : 103)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	1036	Shared Neighborhood Hits	15
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

TE2IP_HUMAN
NC score	0.014400 (rank : 104)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

BPTF_HUMAN
NC score	0.014064 (rank : 105)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	786	Shared Neighborhood Hits	20
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NOTC1_MOUSE
NC score	0.013883 (rank : 106)	θ value	0.0563607 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	916	Shared Neighborhood Hits	11
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FEZ1_HUMAN
NC score	0.013436 (rank : 107)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	Q99689, O00679, O00728, Q6IBI7	Gene names	FEZ1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

CC47_MOUSE
NC score	0.013313 (rank : 108)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

FBN2_MOUSE
NC score	0.012114 (rank : 109)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	549	Shared Neighborhood Hits	8
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

TP53B_HUMAN
NC score	0.011983 (rank : 110)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	413	Shared Neighborhood Hits	12
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ADA18_MOUSE
NC score	0.011644 (rank : 111)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

BCL9_HUMAN
NC score	0.011608 (rank : 112)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	1008	Shared Neighborhood Hits	11
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ZAN_MOUSE
NC score	0.010956 (rank : 113)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	808	Shared Neighborhood Hits	14
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

BRE1A_MOUSE
NC score	0.010912 (rank : 114)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	1025	Shared Neighborhood Hits	30
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

PCSK5_MOUSE
NC score	0.010764 (rank : 115)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	613	Shared Neighborhood Hits	13
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

NOTC1_HUMAN
NC score	0.010385 (rank : 116)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	906	Shared Neighborhood Hits	11
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RAG2_MOUSE
NC score	0.009519 (rank : 117)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

TRI27_HUMAN
NC score	0.009516 (rank : 118)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	273	Shared Neighborhood Hits	24
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.008877 (rank : 119)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	23
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

RO52_HUMAN
NC score	0.007446 (rank : 120)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

PRGC2_MOUSE
NC score	0.007216 (rank : 121)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

DMXL1_HUMAN
NC score	0.006225 (rank : 122)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	259	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

PLXA4_HUMAN
NC score	0.006055 (rank : 123)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

FBXL7_HUMAN
NC score	0.005282 (rank : 124)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

CO7A1_HUMAN
NC score	0.004659 (rank : 125)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	807	Shared Neighborhood Hits	9
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CCD21_MOUSE
NC score	0.003434 (rank : 126)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

JIP3_HUMAN
NC score	0.002998 (rank : 127)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	1039	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

GRID1_HUMAN
NC score	0.002656 (rank : 128)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

PEG3_MOUSE
NC score	0.002609 (rank : 129)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	1101	Shared Neighborhood Hits	14
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RBCC1_HUMAN
NC score	0.002601 (rank : 130)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	1023	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SYNE1_HUMAN
NC score	0.000553 (rank : 131)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	1484	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SALL2_HUMAN
NC score	-0.001355 (rank : 132)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	835	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

MYH3_HUMAN
NC score	-0.001527 (rank : 133)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	1660	Shared Neighborhood Hits	15
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

FLT3_MOUSE
NC score	-0.001891 (rank : 134)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	847	Shared Neighborhood Hits	2
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

WNK2_HUMAN
NC score	-0.003179 (rank : 135)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	1407	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).