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Network neighborhood for query Sequence : RNF31_HUMAN

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RNF31_HUMAN
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RNF31_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	110
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
θ value	0 (rank : 2)	NC score	0.986134 (rank : 2)
Query Neighborhood Hits	110	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

IBRD2_MOUSE
θ value	9.90251e-15 (rank : 3)	NC score	0.616931 (rank : 3)
Query Neighborhood Hits	110	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
θ value	2.43908e-13 (rank : 4)	NC score	0.604096 (rank : 4)
Query Neighborhood Hits	110	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

UB7I4_HUMAN
θ value	1.58096e-12 (rank : 5)	NC score	0.601877 (rank : 5)
Query Neighborhood Hits	110	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
θ value	4.59992e-12 (rank : 6)	NC score	0.599239 (rank : 6)
Query Neighborhood Hits	110	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RBP2_MOUSE
θ value	6.00763e-12 (rank : 7)	NC score	0.171585 (rank : 27)
Query Neighborhood Hits	110	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

ARI2_HUMAN
θ value	3.89403e-11 (rank : 8)	NC score	0.557859 (rank : 7)
Query Neighborhood Hits	110	Target Neighborhood Hits	113	Shared Neighborhood Hits	27
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	5.08577e-11 (rank : 9)	NC score	0.555420 (rank : 8)
Query Neighborhood Hits	110	Target Neighborhood Hits	106	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

PARC_MOUSE
θ value	2.52405e-10 (rank : 10)	NC score	0.429151 (rank : 19)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

RBP2_HUMAN
θ value	1.25267e-09 (rank : 11)	NC score	0.165524 (rank : 28)
Query Neighborhood Hits	110	Target Neighborhood Hits	249	Shared Neighborhood Hits	16
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

ARI1_HUMAN
θ value	1.63604e-09 (rank : 12)	NC score	0.546420 (rank : 9)
Query Neighborhood Hits	110	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	1.63604e-09 (rank : 13)	NC score	0.546313 (rank : 10)
Query Neighborhood Hits	110	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

IBRD3_HUMAN
θ value	2.13673e-09 (rank : 14)	NC score	0.542445 (rank : 11)
Query Neighborhood Hits	110	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	2.79066e-09 (rank : 15)	NC score	0.510430 (rank : 14)
Query Neighborhood Hits	110	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	2.79066e-09 (rank : 16)	NC score	0.512065 (rank : 13)
Query Neighborhood Hits	110	Target Neighborhood Hits	96	Shared Neighborhood Hits	26
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

PARC_HUMAN
θ value	1.80886e-08 (rank : 17)	NC score	0.423928 (rank : 20)
Query Neighborhood Hits	110	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

UB7I3_MOUSE
θ value	6.87365e-08 (rank : 18)	NC score	0.480793 (rank : 17)
Query Neighborhood Hits	110	Target Neighborhood Hits	131	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UB7I3_HUMAN
θ value	1.17247e-07 (rank : 19)	NC score	0.473552 (rank : 18)
Query Neighborhood Hits	110	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

IBRD1_HUMAN
θ value	2.21117e-06 (rank : 20)	NC score	0.539276 (rank : 12)
Query Neighborhood Hits	110	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

RNF14_MOUSE
θ value	4.92598e-06 (rank : 21)	NC score	0.503932 (rank : 15)
Query Neighborhood Hits	110	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

ZRAN1_HUMAN
θ value	1.43324e-05 (rank : 22)	NC score	0.231959 (rank : 25)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

RNF14_HUMAN
θ value	4.1701e-05 (rank : 23)	NC score	0.489709 (rank : 16)
Query Neighborhood Hits	110	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

PRKN2_MOUSE
θ value	0.00228821 (rank : 24)	NC score	0.391690 (rank : 21)
Query Neighborhood Hits	110	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
θ value	0.00390308 (rank : 25)	NC score	0.387565 (rank : 22)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

UB7I1_MOUSE
θ value	0.00390308 (rank : 26)	NC score	0.351570 (rank : 23)
Query Neighborhood Hits	110	Target Neighborhood Hits	206	Shared Neighborhood Hits	28
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
θ value	0.00509761 (rank : 27)	NC score	0.350410 (rank : 24)
Query Neighborhood Hits	110	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

NU153_HUMAN
θ value	0.0113563 (rank : 28)	NC score	0.197733 (rank : 26)
Query Neighborhood Hits	110	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

NPL4_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.149142 (rank : 30)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.149265 (rank : 29)
Query Neighborhood Hits	110	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

TAB2_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.111803 (rank : 35)
Query Neighborhood Hits	110	Target Neighborhood Hits	245	Shared Neighborhood Hits	21
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

RYBP_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.147150 (rank : 31)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

RYBP_MOUSE
θ value	0.163984 (rank : 33)	NC score	0.145509 (rank : 33)
Query Neighborhood Hits	110	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

CU030_HUMAN
θ value	0.279714 (rank : 34)	NC score	0.068816 (rank : 54)
Query Neighborhood Hits	110	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

ZN565_HUMAN
θ value	0.279714 (rank : 35)	NC score	0.001707 (rank : 117)
Query Neighborhood Hits	110	Target Neighborhood Hits	743	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N9K5, Q6NUS2	Gene names	ZNF565
Domain Architecture	No domain graphic available
Description	Zinc finger protein 565.

RUFY1_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.035033 (rank : 73)
Query Neighborhood Hits	110	Target Neighborhood Hits	848	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

TAB2_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.110010 (rank : 36)
Query Neighborhood Hits	110	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TAB3_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.096474 (rank : 38)
Query Neighborhood Hits	110	Target Neighborhood Hits	168	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

MINK1_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.002040 (rank : 116)
Query Neighborhood Hits	110	Target Neighborhood Hits	1451	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

STAB2_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.012813 (rank : 99)
Query Neighborhood Hits	110	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

UBQL3_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.077588 (rank : 48)
Query Neighborhood Hits	110	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

UBQL4_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.085601 (rank : 43)
Query Neighborhood Hits	110	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

UBQL4_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.078996 (rank : 47)
Query Neighborhood Hits	110	Target Neighborhood Hits	99	Shared Neighborhood Hits	11
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

CT012_MOUSE
θ value	0.813845 (rank : 44)	NC score	0.052672 (rank : 56)
Query Neighborhood Hits	110	Target Neighborhood Hits	229	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

RNF4_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.080980 (rank : 46)
Query Neighborhood Hits	110	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RUFY2_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.030479 (rank : 75)
Query Neighborhood Hits	110	Target Neighborhood Hits	820	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

TAB3_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.094113 (rank : 39)
Query Neighborhood Hits	110	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

YAF2_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.128717 (rank : 34)
Query Neighborhood Hits	110	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY57, Q99710	Gene names	YAF2
Domain Architecture
Description	YY1-associated factor 2.

ZFAN1_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.060120 (rank : 55)
Query Neighborhood Hits	110	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCF1, Q658R7, Q6IA32, Q6PGQ6, Q9H810	Gene names	ZFAND1
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 1.

ZN409_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.021238 (rank : 89)
Query Neighborhood Hits	110	Target Neighborhood Hits	842	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

RNF4_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.069252 (rank : 53)
Query Neighborhood Hits	110	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RSPO1_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.035231 (rank : 72)
Query Neighborhood Hits	110	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

ABLM1_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.017087 (rank : 94)
Query Neighborhood Hits	110	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

HEAT2_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.039820 (rank : 70)
Query Neighborhood Hits	110	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

RUFY1_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.028364 (rank : 77)
Query Neighborhood Hits	110	Target Neighborhood Hits	765	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

YAF2_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.146839 (rank : 32)
Query Neighborhood Hits	110	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

PML_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.040641 (rank : 69)
Query Neighborhood Hits	110	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RBNS5_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.035607 (rank : 71)
Query Neighborhood Hits	110	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

TIF1A_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.025370 (rank : 82)
Query Neighborhood Hits	110	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.026089 (rank : 80)
Query Neighborhood Hits	110	Target Neighborhood Hits	307	Shared Neighborhood Hits	14
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

UBQL1_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.071633 (rank : 49)
Query Neighborhood Hits	110	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UMX0, Q8IXS9, Q8N2Q3, Q9H0T8, Q9H3R4, Q9HAZ5	Gene names	UBQLN1, DA41, PLIC1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC- 1).

UBQL1_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.071008 (rank : 51)
Query Neighborhood Hits	110	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R317, Q80V10, Q8C7T4, Q8C835, Q8K141, Q91VI8, Q9D0Z0, Q9QZM1	Gene names	Ubqln1, Plic1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1).

UBQL2_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.071201 (rank : 50)
Query Neighborhood Hits	110	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

UBQL2_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.070275 (rank : 52)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

ABLM1_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.017045 (rank : 95)
Query Neighborhood Hits	110	Target Neighborhood Hits	356	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

AF10_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.026358 (rank : 79)
Query Neighborhood Hits	110	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.025567 (rank : 81)
Query Neighborhood Hits	110	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

FGD3_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.014979 (rank : 98)
Query Neighborhood Hits	110	Target Neighborhood Hits	249	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

PCGF6_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.048201 (rank : 64)
Query Neighborhood Hits	110	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.048024 (rank : 65)
Query Neighborhood Hits	110	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

UBXD1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.046631 (rank : 66)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

BC11B_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.002648 (rank : 115)
Query Neighborhood Hits	110	Target Neighborhood Hits	767	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

KCNS1_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.006640 (rank : 109)
Query Neighborhood Hits	110	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

LTBP4_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.008605 (rank : 105)
Query Neighborhood Hits	110	Target Neighborhood Hits	607	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TRI46_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.031367 (rank : 74)
Query Neighborhood Hits	110	Target Neighborhood Hits	287	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

AOC3_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.012329 (rank : 101)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O70423, Q66JM4, Q9R055	Gene names	Aoc3, Vap1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1).

ATBF1_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.006862 (rank : 108)
Query Neighborhood Hits	110	Target Neighborhood Hits	1547	Shared Neighborhood Hits	13
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CHFR_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.051863 (rank : 57)
Query Neighborhood Hits	110	Target Neighborhood Hits	255	Shared Neighborhood Hits	25
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.049772 (rank : 63)
Query Neighborhood Hits	110	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI46_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.029976 (rank : 76)
Query Neighborhood Hits	110	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

Z585B_HUMAN
θ value	4.03905 (rank : 81)	NC score	-0.000509 (rank : 119)
Query Neighborhood Hits	110	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q52M93, Q8IZD3, Q96JW6	Gene names	ZNF585B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 585B (zinc finger protein 41-like protein).

FYV1_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.023224 (rank : 84)
Query Neighborhood Hits	110	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

IBP1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.011963 (rank : 103)
Query Neighborhood Hits	110	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

KCC4_HUMAN
θ value	5.27518 (rank : 84)	NC score	-0.000882 (rank : 120)
Query Neighborhood Hits	110	Target Neighborhood Hits	841	Shared Neighborhood Hits	4
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KCC4_MOUSE
θ value	5.27518 (rank : 85)	NC score	-0.000951 (rank : 121)
Query Neighborhood Hits	110	Target Neighborhood Hits	899	Shared Neighborhood Hits	4
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

RN126_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.023196 (rank : 85)
Query Neighborhood Hits	110	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RUFY2_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.016937 (rank : 96)
Query Neighborhood Hits	110	Target Neighborhood Hits	1208	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

TRIM8_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.019804 (rank : 91)
Query Neighborhood Hits	110	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.020026 (rank : 90)
Query Neighborhood Hits	110	Target Neighborhood Hits	674	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UBP50_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.007561 (rank : 107)
Query Neighborhood Hits	110	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

WDR24_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.016053 (rank : 97)
Query Neighborhood Hits	110	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR24_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.012322 (rank : 102)
Query Neighborhood Hits	110	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

ZAR1_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.017619 (rank : 93)
Query Neighborhood Hits	110	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN438_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.011545 (rank : 104)
Query Neighborhood Hits	110	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ADA28_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.005070 (rank : 112)
Query Neighborhood Hits	110	Target Neighborhood Hits	241	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ANKS6_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.003300 (rank : 114)
Query Neighborhood Hits	110	Target Neighborhood Hits	435	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

NEIL3_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.043724 (rank : 67)
Query Neighborhood Hits	110	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

RN126_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.023606 (rank : 83)
Query Neighborhood Hits	110	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZRAB2_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.042295 (rank : 68)
Query Neighborhood Hits	110	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

EEA1_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.005658 (rank : 110)
Query Neighborhood Hits	110	Target Neighborhood Hits	1637	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ITSN2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.001598 (rank : 118)
Query Neighborhood Hits	110	Target Neighborhood Hits	1371	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NALP6_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.005163 (rank : 111)
Query Neighborhood Hits	110	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

RBNS5_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.028283 (rank : 78)
Query Neighborhood Hits	110	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RSPO4_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.019128 (rank : 92)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SMOC2_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.008025 (rank : 106)
Query Neighborhood Hits	110	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

TIF1G_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.022364 (rank : 87)
Query Neighborhood Hits	110	Target Neighborhood Hits	410	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.021902 (rank : 88)
Query Neighborhood Hits	110	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIM_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.012575 (rank : 100)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

UBXD1_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.022388 (rank : 86)
Query Neighborhood Hits	110	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PL6, Q91W79	Gene names	Ubxd1, Ubxdc2
Domain Architecture
Description	UBX domain-containing protein 1.

ZF106_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.004853 (rank : 113)
Query Neighborhood Hits	110	Target Neighborhood Hits	470	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

CUL7_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.106158 (rank : 37)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

PPIA_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.050332 (rank : 60)
Query Neighborhood Hits	110	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

PPIA_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.050371 (rank : 59)
Query Neighborhood Hits	110	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIF_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.050057 (rank : 62)
Query Neighborhood Hits	110	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P30405, Q5W131	Gene names	PPIF, CYP3
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIF_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.050872 (rank : 58)
Query Neighborhood Hits	110	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KR7	Gene names	Ppif
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

RANG_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.084287 (rank : 45)
Query Neighborhood Hits	110	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

RANG_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.084885 (rank : 44)
Query Neighborhood Hits	110	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RBP22_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.088582 (rank : 41)
Query Neighborhood Hits	110	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RBP26_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.088560 (rank : 42)
Query Neighborhood Hits	110	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RGPD8_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.088705 (rank : 40)
Query Neighborhood Hits	110	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

UBQL3_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.050147 (rank : 61)
Query Neighborhood Hits	110	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

Hits sorted by NC score

RNF31_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	110
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.986134 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	110	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

IBRD2_MOUSE
NC score	0.616931 (rank : 3)	θ value	9.90251e-15 (rank : 3)
Query Neighborhood Hits	110	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
NC score	0.604096 (rank : 4)	θ value	2.43908e-13 (rank : 4)
Query Neighborhood Hits	110	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

UB7I4_HUMAN
NC score	0.601877 (rank : 5)	θ value	1.58096e-12 (rank : 5)
Query Neighborhood Hits	110	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
NC score	0.599239 (rank : 6)	θ value	4.59992e-12 (rank : 6)
Query Neighborhood Hits	110	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ARI2_HUMAN
NC score	0.557859 (rank : 7)	θ value	3.89403e-11 (rank : 8)
Query Neighborhood Hits	110	Target Neighborhood Hits	113	Shared Neighborhood Hits	27
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.555420 (rank : 8)	θ value	5.08577e-11 (rank : 9)
Query Neighborhood Hits	110	Target Neighborhood Hits	106	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI1_HUMAN
NC score	0.546420 (rank : 9)	θ value	1.63604e-09 (rank : 12)
Query Neighborhood Hits	110	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.546313 (rank : 10)	θ value	1.63604e-09 (rank : 13)
Query Neighborhood Hits	110	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

IBRD3_HUMAN
NC score	0.542445 (rank : 11)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	110	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

IBRD1_HUMAN
NC score	0.539276 (rank : 12)	θ value	2.21117e-06 (rank : 20)
Query Neighborhood Hits	110	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

RNF19_MOUSE
NC score	0.512065 (rank : 13)	θ value	2.79066e-09 (rank : 16)
Query Neighborhood Hits	110	Target Neighborhood Hits	96	Shared Neighborhood Hits	26
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.510430 (rank : 14)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	110	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF14_MOUSE
NC score	0.503932 (rank : 15)	θ value	4.92598e-06 (rank : 21)
Query Neighborhood Hits	110	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF14_HUMAN
NC score	0.489709 (rank : 16)	θ value	4.1701e-05 (rank : 23)
Query Neighborhood Hits	110	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

UB7I3_MOUSE
NC score	0.480793 (rank : 17)	θ value	6.87365e-08 (rank : 18)
Query Neighborhood Hits	110	Target Neighborhood Hits	131	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UB7I3_HUMAN
NC score	0.473552 (rank : 18)	θ value	1.17247e-07 (rank : 19)
Query Neighborhood Hits	110	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

PARC_MOUSE
NC score	0.429151 (rank : 19)	θ value	2.52405e-10 (rank : 10)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PARC_HUMAN
NC score	0.423928 (rank : 20)	θ value	1.80886e-08 (rank : 17)
Query Neighborhood Hits	110	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PRKN2_MOUSE
NC score	0.391690 (rank : 21)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	110	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
NC score	0.387565 (rank : 22)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

UB7I1_MOUSE
NC score	0.351570 (rank : 23)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	110	Target Neighborhood Hits	206	Shared Neighborhood Hits	28
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
NC score	0.350410 (rank : 24)	θ value	0.00509761 (rank : 27)
Query Neighborhood Hits	110	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ZRAN1_HUMAN
NC score	0.231959 (rank : 25)	θ value	1.43324e-05 (rank : 22)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

NU153_HUMAN
NC score	0.197733 (rank : 26)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	110	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

RBP2_MOUSE
NC score	0.171585 (rank : 27)	θ value	6.00763e-12 (rank : 7)
Query Neighborhood Hits	110	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RBP2_HUMAN
NC score	0.165524 (rank : 28)	θ value	1.25267e-09 (rank : 11)
Query Neighborhood Hits	110	Target Neighborhood Hits	249	Shared Neighborhood Hits	16
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

NPL4_MOUSE
NC score	0.149265 (rank : 29)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	110	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_HUMAN
NC score	0.149142 (rank : 30)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

RYBP_HUMAN
NC score	0.147150 (rank : 31)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

YAF2_MOUSE
NC score	0.146839 (rank : 32)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	110	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

RYBP_MOUSE
NC score	0.145509 (rank : 33)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	110	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

YAF2_HUMAN
NC score	0.128717 (rank : 34)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	110	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY57, Q99710	Gene names	YAF2
Domain Architecture
Description	YY1-associated factor 2.

TAB2_MOUSE
NC score	0.111803 (rank : 35)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	110	Target Neighborhood Hits	245	Shared Neighborhood Hits	21
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TAB2_HUMAN
NC score	0.110010 (rank : 36)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	110	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

CUL7_HUMAN
NC score	0.106158 (rank : 37)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

TAB3_HUMAN
NC score	0.096474 (rank : 38)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	110	Target Neighborhood Hits	168	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TAB3_MOUSE
NC score	0.094113 (rank : 39)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	110	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

RGPD8_HUMAN
NC score	0.088705 (rank : 40)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	110	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

RBP22_HUMAN
NC score	0.088582 (rank : 41)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	110	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RBP26_HUMAN
NC score	0.088560 (rank : 42)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	110	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

UBQL4_HUMAN
NC score	0.085601 (rank : 43)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	110	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

RANG_MOUSE
NC score	0.084885 (rank : 44)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	110	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RANG_HUMAN
NC score	0.084287 (rank : 45)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	110	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

RNF4_HUMAN
NC score	0.080980 (rank : 46)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	110	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

UBQL4_MOUSE
NC score	0.078996 (rank : 47)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	110	Target Neighborhood Hits	99	Shared Neighborhood Hits	11
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

UBQL3_HUMAN
NC score	0.077588 (rank : 48)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	110	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

UBQL1_HUMAN
NC score	0.071633 (rank : 49)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	110	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UMX0, Q8IXS9, Q8N2Q3, Q9H0T8, Q9H3R4, Q9HAZ5	Gene names	UBQLN1, DA41, PLIC1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC- 1).

UBQL2_HUMAN
NC score	0.071201 (rank : 50)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	110	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

UBQL1_MOUSE
NC score	0.071008 (rank : 51)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	110	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R317, Q80V10, Q8C7T4, Q8C835, Q8K141, Q91VI8, Q9D0Z0, Q9QZM1	Gene names	Ubqln1, Plic1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1).

UBQL2_MOUSE
NC score	0.070275 (rank : 52)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

RNF4_MOUSE
NC score	0.069252 (rank : 53)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	110	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

CU030_HUMAN
NC score	0.068816 (rank : 54)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	110	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

ZFAN1_HUMAN
NC score	0.060120 (rank : 55)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	110	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCF1, Q658R7, Q6IA32, Q6PGQ6, Q9H810	Gene names	ZFAND1
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 1.

CT012_MOUSE
NC score	0.052672 (rank : 56)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	110	Target Neighborhood Hits	229	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

CHFR_HUMAN
NC score	0.051863 (rank : 57)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	110	Target Neighborhood Hits	255	Shared Neighborhood Hits	25
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PPIF_MOUSE
NC score	0.050872 (rank : 58)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	110	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KR7	Gene names	Ppif
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIA_MOUSE
NC score	0.050371 (rank : 59)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	110	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIA_HUMAN
NC score	0.050332 (rank : 60)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	110	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

UBQL3_MOUSE
NC score	0.050147 (rank : 61)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	110	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

PPIF_HUMAN
NC score	0.050057 (rank : 62)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	110	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P30405, Q5W131	Gene names	PPIF, CYP3
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

CHFR_MOUSE
NC score	0.049772 (rank : 63)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	110	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PCGF6_HUMAN
NC score	0.048201 (rank : 64)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	110	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
NC score	0.048024 (rank : 65)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	110	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

UBXD1_HUMAN
NC score	0.046631 (rank : 66)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

NEIL3_MOUSE
NC score	0.043724 (rank : 67)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	110	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

ZRAB2_HUMAN
NC score	0.042295 (rank : 68)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	110	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

PML_HUMAN
NC score	0.040641 (rank : 69)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	110	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

HEAT2_HUMAN
NC score	0.039820 (rank : 70)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	110	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

RBNS5_HUMAN
NC score	0.035607 (rank : 71)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	110	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RSPO1_MOUSE
NC score	0.035231 (rank : 72)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	110	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RUFY1_HUMAN
NC score	0.035033 (rank : 73)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	110	Target Neighborhood Hits	848	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

TRI46_MOUSE
NC score	0.031367 (rank : 74)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	110	Target Neighborhood Hits	287	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RUFY2_MOUSE
NC score	0.030479 (rank : 75)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	110	Target Neighborhood Hits	820	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

TRI46_HUMAN
NC score	0.029976 (rank : 76)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	110	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RUFY1_MOUSE
NC score	0.028364 (rank : 77)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	110	Target Neighborhood Hits	765	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RBNS5_MOUSE
NC score	0.028283 (rank : 78)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	110	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

AF10_HUMAN
NC score	0.026358 (rank : 79)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	110	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

TIF1A_MOUSE
NC score	0.026089 (rank : 80)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	110	Target Neighborhood Hits	307	Shared Neighborhood Hits	14
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

AF10_MOUSE
NC score	0.025567 (rank : 81)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	110	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

TIF1A_HUMAN
NC score	0.025370 (rank : 82)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	110	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

RN126_MOUSE
NC score	0.023606 (rank : 83)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	110	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

FYV1_MOUSE
NC score	0.023224 (rank : 84)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	110	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

RN126_HUMAN
NC score	0.023196 (rank : 85)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	110	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

UBXD1_MOUSE
NC score	0.022388 (rank : 86)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	110	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PL6, Q91W79	Gene names	Ubxd1, Ubxdc2
Domain Architecture
Description	UBX domain-containing protein 1.

TIF1G_HUMAN
NC score	0.022364 (rank : 87)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	110	Target Neighborhood Hits	410	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.021902 (rank : 88)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	110	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZN409_HUMAN
NC score	0.021238 (rank : 89)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	110	Target Neighborhood Hits	842	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

TRIM8_MOUSE
NC score	0.020026 (rank : 90)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	110	Target Neighborhood Hits	674	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.019804 (rank : 91)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	110	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RSPO4_HUMAN
NC score	0.019128 (rank : 92)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

ZAR1_HUMAN
NC score	0.017619 (rank : 93)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	110	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ABLM1_HUMAN
NC score	0.017087 (rank : 94)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	110	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ABLM1_MOUSE
NC score	0.017045 (rank : 95)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	110	Target Neighborhood Hits	356	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

RUFY2_HUMAN
NC score	0.016937 (rank : 96)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	110	Target Neighborhood Hits	1208	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

WDR24_HUMAN
NC score	0.016053 (rank : 97)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	110	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

FGD3_HUMAN
NC score	0.014979 (rank : 98)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	110	Target Neighborhood Hits	249	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

STAB2_HUMAN
NC score	0.012813 (rank : 99)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	110	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TIM_MOUSE
NC score	0.012575 (rank : 100)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

AOC3_MOUSE
NC score	0.012329 (rank : 101)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O70423, Q66JM4, Q9R055	Gene names	Aoc3, Vap1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1).

WDR24_MOUSE
NC score	0.012322 (rank : 102)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	110	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

IBP1_MOUSE
NC score	0.011963 (rank : 103)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	110	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

ZN438_HUMAN
NC score	0.011545 (rank : 104)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	110	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

LTBP4_MOUSE
NC score	0.008605 (rank : 105)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	110	Target Neighborhood Hits	607	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

SMOC2_HUMAN
NC score	0.008025 (rank : 106)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	110	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

UBP50_HUMAN
NC score	0.007561 (rank : 107)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	110	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

ATBF1_HUMAN
NC score	0.006862 (rank : 108)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	110	Target Neighborhood Hits	1547	Shared Neighborhood Hits	13
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

KCNS1_HUMAN
NC score	0.006640 (rank : 109)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	110	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

EEA1_MOUSE
NC score	0.005658 (rank : 110)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	110	Target Neighborhood Hits	1637	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

NALP6_HUMAN
NC score	0.005163 (rank : 111)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	110	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

ADA28_MOUSE
NC score	0.005070 (rank : 112)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	110	Target Neighborhood Hits	241	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ZF106_HUMAN
NC score	0.004853 (rank : 113)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	110	Target Neighborhood Hits	470	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ANKS6_MOUSE
NC score	0.003300 (rank : 114)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	110	Target Neighborhood Hits	435	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

BC11B_MOUSE
NC score	0.002648 (rank : 115)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	110	Target Neighborhood Hits	767	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

MINK1_MOUSE
NC score	0.002040 (rank : 116)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	110	Target Neighborhood Hits	1451	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

ZN565_HUMAN
NC score	0.001707 (rank : 117)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	110	Target Neighborhood Hits	743	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N9K5, Q6NUS2	Gene names	ZNF565
Domain Architecture	No domain graphic available
Description	Zinc finger protein 565.

ITSN2_MOUSE
NC score	0.001598 (rank : 118)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	110	Target Neighborhood Hits	1371	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

Z585B_HUMAN
NC score	-0.000509 (rank : 119)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	110	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q52M93, Q8IZD3, Q96JW6	Gene names	ZNF585B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 585B (zinc finger protein 41-like protein).

KCC4_HUMAN
NC score	-0.000882 (rank : 120)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	110	Target Neighborhood Hits	841	Shared Neighborhood Hits	4
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KCC4_MOUSE
NC score	-0.000951 (rank : 121)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	110	Target Neighborhood Hits	899	Shared Neighborhood Hits	4
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).