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Network neighborhood for query Sequence : ARI2_HUMAN

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ARI2_HUMAN
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARI2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	0 (rank : 2)	NC score	0.998701 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI1_HUMAN
θ value	3.22841e-82 (rank : 3)	NC score	0.938113 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	3.22841e-82 (rank : 4)	NC score	0.937932 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

PARC_HUMAN
θ value	2.67181e-44 (rank : 5)	NC score	0.704588 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	148	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	2.19075e-38 (rank : 6)	NC score	0.688157 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

UB7I4_MOUSE
θ value	1.09232e-21 (rank : 7)	NC score	0.785389 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RNF14_HUMAN
θ value	2.43343e-21 (rank : 8)	NC score	0.774019 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

UB7I4_HUMAN
θ value	2.43343e-21 (rank : 9)	NC score	0.785173 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RNF14_MOUSE
θ value	4.15078e-21 (rank : 10)	NC score	0.774210 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

IBRD2_HUMAN
θ value	5.99374e-20 (rank : 11)	NC score	0.761356 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD2_MOUSE
θ value	8.65492e-19 (rank : 12)	NC score	0.760407 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD3_HUMAN
θ value	4.29542e-18 (rank : 13)	NC score	0.734011 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	4.74913e-17 (rank : 14)	NC score	0.695025 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	4.74913e-17 (rank : 15)	NC score	0.697484 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

PRKN2_MOUSE
θ value	1.29331e-14 (rank : 16)	NC score	0.654986 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
θ value	3.76295e-14 (rank : 17)	NC score	0.653413 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

IBRD1_HUMAN
θ value	1.02475e-11 (rank : 18)	NC score	0.735541 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

RNF31_MOUSE
θ value	2.28291e-11 (rank : 19)	NC score	0.557230 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	29
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

RNF31_HUMAN
θ value	3.89403e-11 (rank : 20)	NC score	0.557859 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UB7I1_MOUSE
θ value	1.25267e-09 (rank : 21)	NC score	0.524064 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
θ value	2.13673e-09 (rank : 22)	NC score	0.523999 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I3_MOUSE
θ value	4.0297e-08 (rank : 23)	NC score	0.562304 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	131	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UB7I3_HUMAN
θ value	4.45536e-07 (rank : 24)	NC score	0.558727 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	136	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

TRIM7_MOUSE
θ value	0.00175202 (rank : 25)	NC score	0.082380 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	358	Shared Neighborhood Hits	51
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI36_HUMAN
θ value	0.00665767 (rank : 26)	NC score	0.085336 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	282	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

RN146_HUMAN
θ value	0.0193708 (rank : 27)	NC score	0.129517 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.0431538 (rank : 28)	NC score	0.123891 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RIMS1_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.034620 (rank : 118)
Query Neighborhood Hits	113	Target Neighborhood Hits	437	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TRAF6_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.066925 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TOPRS_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.105885 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	286	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.107320 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	263	Shared Neighborhood Hits	41
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ZFP95_MOUSE
θ value	0.0961366 (rank : 33)	NC score	0.007208 (rank : 141)
Query Neighborhood Hits	113	Target Neighborhood Hits	787	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1D8	Gene names	Zfp95
Domain Architecture
Description	Zinc finger protein 95 (Zfp-95).

PRD14_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.009359 (rank : 136)
Query Neighborhood Hits	113	Target Neighborhood Hits	757	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

RNF5_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.104449 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	206	Shared Neighborhood Hits	43
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI36_MOUSE
θ value	0.163984 (rank : 36)	NC score	0.078252 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

PEX10_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.117525 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRIM9_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.094101 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	294	Shared Neighborhood Hits	43
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.092338 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	274	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RNF5_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.102090 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	206	Shared Neighborhood Hits	42
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRIM7_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.065042 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	336	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI62_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.067460 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	584	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.069756 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	478	Shared Neighborhood Hits	54
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM6_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.066157 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	412	Shared Neighborhood Hits	49
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI40_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.080970 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	279	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI68_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.066719 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	356	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

GOLI_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.044774 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

MATR3_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.024861 (rank : 124)
Query Neighborhood Hits	113	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MLL4_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.025715 (rank : 123)
Query Neighborhood Hits	113	Target Neighborhood Hits	722	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TRI55_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.064139 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	292	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI68_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.063755 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	267	Shared Neighborhood Hits	47
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RN185_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.092590 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	48
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.092028 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRAF6_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.064524 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	267	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRIM6_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.061918 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	451	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

ZN179_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.068924 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN260_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.003980 (rank : 144)
Query Neighborhood Hits	113	Target Neighborhood Hits	765	Shared Neighborhood Hits	13
SwissProt Accessions	Q62513, Q3U170, Q8C2Q6, Q9R2B4	Gene names	Znf260, Zfp260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

DZIP3_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.030966 (rank : 120)
Query Neighborhood Hits	113	Target Neighborhood Hits	414	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

PCSK5_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.011353 (rank : 133)
Query Neighborhood Hits	113	Target Neighborhood Hits	613	Shared Neighborhood Hits	16
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TRI22_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.069437 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

ATS20_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.009103 (rank : 138)
Query Neighborhood Hits	113	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

BRAP_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.035813 (rank : 115)
Query Neighborhood Hits	113	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.040340 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	409	Shared Neighborhood Hits	30
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CYLN2_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.005066 (rank : 142)
Query Neighborhood Hits	113	Target Neighborhood Hits	1004	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

STAB2_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.008493 (rank : 139)
Query Neighborhood Hits	113	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TRI10_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.075631 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	315	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI30_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.061570 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	434	Shared Neighborhood Hits	53
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI52_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.068622 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

ZN605_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.003598 (rank : 146)
Query Neighborhood Hits	113	Target Neighborhood Hits	753	Shared Neighborhood Hits	14
SwissProt Accessions	Q86T29, Q86T91	Gene names	ZNF605
Domain Architecture	No domain graphic available
Description	Zinc finger protein 605.

LDLR_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.012930 (rank : 128)
Query Neighborhood Hits	113	Target Neighborhood Hits	382	Shared Neighborhood Hits	9
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MLL2_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.020377 (rank : 125)
Query Neighborhood Hits	113	Target Neighborhood Hits	1788	Shared Neighborhood Hits	22
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PML_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.036730 (rank : 114)
Query Neighborhood Hits	113	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI10_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.081148 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI41_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.058962 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	349	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI46_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.062156 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	287	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

VLDLR_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.012801 (rank : 129)
Query Neighborhood Hits	113	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZIM3_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.003299 (rank : 148)
Query Neighborhood Hits	113	Target Neighborhood Hits	765	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PE6	Gene names	ZIM3
Domain Architecture
Description	Zinc finger imprinted 3.

ZN615_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.003650 (rank : 145)
Query Neighborhood Hits	113	Target Neighborhood Hits	775	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

CQ050_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.038516 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C1R3, Q9DAI8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50 homolog.

FBX43_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.066618 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FLIP1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.002498 (rank : 154)
Query Neighborhood Hits	113	Target Neighborhood Hits	1405	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

LRP8_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.012063 (rank : 130)
Query Neighborhood Hits	113	Target Neighborhood Hits	385	Shared Neighborhood Hits	10
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PRLC2_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.009302 (rank : 137)
Query Neighborhood Hits	113	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQ58	Gene names	Prlpc2
Domain Architecture	No domain graphic available
Description	Placental prolactin-like protein C2 precursor (PRL-like protein C2) (PLP-C2) (Prolactin-like protein C-beta) (PLP C-beta).

RN122_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.037849 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF39_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.053656 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	200	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

SEC63_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.016441 (rank : 127)
Query Neighborhood Hits	113	Target Neighborhood Hits	601	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TRI17_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.053556 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	318	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

ZNF26_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.003257 (rank : 150)
Query Neighborhood Hits	113	Target Neighborhood Hits	736	Shared Neighborhood Hits	14
SwissProt Accessions	P17031, Q9NWL3	Gene names	ZNF26, KOX20
Domain Architecture	No domain graphic available
Description	Zinc finger protein 26 (Zinc finger protein KOX20).

ZNF91_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.003331 (rank : 147)
Query Neighborhood Hits	113	Target Neighborhood Hits	797	Shared Neighborhood Hits	14
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

ATS9_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.007646 (rank : 140)
Query Neighborhood Hits	113	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CQ050_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.035759 (rank : 116)
Query Neighborhood Hits	113	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WW18, Q6Q621	Gene names	C17orf50
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50.

FLIP1_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.003295 (rank : 149)
Query Neighborhood Hits	113	Target Neighborhood Hits	1176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MATR3_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.018773 (rank : 126)
Query Neighborhood Hits	113	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

R113A_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.045285 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RN122_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.032705 (rank : 119)
Query Neighborhood Hits	113	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

TRI26_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.064581 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	335	Shared Neighborhood Hits	56
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.065171 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	339	Shared Neighborhood Hits	54
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI35_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.064053 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI46_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.061039 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	291	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ZN649_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.003020 (rank : 151)
Query Neighborhood Hits	113	Target Neighborhood Hits	745	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BS31, Q9H9N2	Gene names	ZNF649
Domain Architecture	No domain graphic available
Description	Zinc finger protein 649.

ATS7_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.004514 (rank : 143)
Query Neighborhood Hits	113	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

CNOT4_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.030869 (rank : 121)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	15
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.029500 (rank : 122)
Query Neighborhood Hits	113	Target Neighborhood Hits	277	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

LDLR_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.010904 (rank : 135)
Query Neighborhood Hits	113	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MKRN3_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.034657 (rank : 117)
Query Neighborhood Hits	113	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

SMG1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.011623 (rank : 132)
Query Neighborhood Hits	113	Target Neighborhood Hits	231	Shared Neighborhood Hits	5
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMG1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.011738 (rank : 131)
Query Neighborhood Hits	113	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

TRI25_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.056505 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	472	Shared Neighborhood Hits	56
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI39_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.052493 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	693	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI60_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.054651 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	357	Shared Neighborhood Hits	51
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

VEZF1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.002768 (rank : 152)
Query Neighborhood Hits	113	Target Neighborhood Hits	744	Shared Neighborhood Hits	14
SwissProt Accessions	Q14119	Gene names	VEZF1, DB1, ZNF161
Domain Architecture	No domain graphic available
Description	Vascular endothelial zinc finger 1 (Zinc finger protein 161) (Putative transcription factor DB1).

VLDLR_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.011022 (rank : 134)
Query Neighborhood Hits	113	Target Neighborhood Hits	360	Shared Neighborhood Hits	11
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZN510_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.002668 (rank : 153)
Query Neighborhood Hits	113	Target Neighborhood Hits	764	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2H8	Gene names	ZNF510, KIAA0972
Domain Architecture
Description	Zinc finger protein 510.

CUL7_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.213794 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

FBX43_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.054603 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	9
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.059342 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.059404 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

RNF4_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.056730 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	212	Shared Neighborhood Hits	43
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.054148 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	212	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RO52_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.052013 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	419	Shared Neighborhood Hits	55
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

RO52_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.054787 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	360	Shared Neighborhood Hits	50
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI11_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.051010 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	316	Shared Neighborhood Hits	45
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI12_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.050950 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	387	Shared Neighborhood Hits	44
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.052739 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.052535 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	282	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI15_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.053774 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.050382 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	620	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI27_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.055060 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.054195 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	261	Shared Neighborhood Hits	50
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI31_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.056566 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	299	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.055672 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	264	Shared Neighborhood Hits	50
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.050426 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.052044 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	416	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI35_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.056276 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	465	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI38_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.055908 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	373	Shared Neighborhood Hits	51
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI39_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.051629 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	691	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI50_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.053688 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	294	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.056374 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	326	Shared Neighborhood Hits	48
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI56_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.050973 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI59_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.052582 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.052718 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	292	Shared Neighborhood Hits	49
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI65_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.051251 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	330	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.052237 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.051738 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	249	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.052533 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	345	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.050683 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	361	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM2_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.060543 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	330	Shared Neighborhood Hits	60
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.059854 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.063952 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	357	Shared Neighborhood Hits	58
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.060509 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	351	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM4_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.051020 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	321	Shared Neighborhood Hits	48
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM5_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.057805 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	424	Shared Neighborhood Hits	52
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM8_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.052184 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.053060 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	674	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

Hits sorted by NC score

ARI2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.998701 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI1_HUMAN
NC score	0.938113 (rank : 3)	θ value	3.22841e-82 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.937932 (rank : 4)	θ value	3.22841e-82 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

UB7I4_MOUSE
NC score	0.785389 (rank : 5)	θ value	1.09232e-21 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
NC score	0.785173 (rank : 6)	θ value	2.43343e-21 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RNF14_MOUSE
NC score	0.774210 (rank : 7)	θ value	4.15078e-21 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF14_HUMAN
NC score	0.774019 (rank : 8)	θ value	2.43343e-21 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

IBRD2_HUMAN
NC score	0.761356 (rank : 9)	θ value	5.99374e-20 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD2_MOUSE
NC score	0.760407 (rank : 10)	θ value	8.65492e-19 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD1_HUMAN
NC score	0.735541 (rank : 11)	θ value	1.02475e-11 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

IBRD3_HUMAN
NC score	0.734011 (rank : 12)	θ value	4.29542e-18 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

PARC_HUMAN
NC score	0.704588 (rank : 13)	θ value	2.67181e-44 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	148	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

RNF19_MOUSE
NC score	0.697484 (rank : 14)	θ value	4.74913e-17 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.695025 (rank : 15)	θ value	4.74913e-17 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

PARC_MOUSE
NC score	0.688157 (rank : 16)	θ value	2.19075e-38 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PRKN2_MOUSE
NC score	0.654986 (rank : 17)	θ value	1.29331e-14 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
NC score	0.653413 (rank : 18)	θ value	3.76295e-14 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

UB7I3_MOUSE
NC score	0.562304 (rank : 19)	θ value	4.0297e-08 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	131	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UB7I3_HUMAN
NC score	0.558727 (rank : 20)	θ value	4.45536e-07 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	136	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RNF31_HUMAN
NC score	0.557859 (rank : 21)	θ value	3.89403e-11 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.557230 (rank : 22)	θ value	2.28291e-11 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	29
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

UB7I1_MOUSE
NC score	0.524064 (rank : 23)	θ value	1.25267e-09 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
NC score	0.523999 (rank : 24)	θ value	2.13673e-09 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

CUL7_HUMAN
NC score	0.213794 (rank : 25)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	113	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

RN146_HUMAN
NC score	0.129517 (rank : 26)	θ value	0.0193708 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.123891 (rank : 27)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

PEX10_HUMAN
NC score	0.117525 (rank : 28)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TOPRS_MOUSE
NC score	0.107320 (rank : 29)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	263	Shared Neighborhood Hits	41
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.105885 (rank : 30)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	286	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RNF5_HUMAN
NC score	0.104449 (rank : 31)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	206	Shared Neighborhood Hits	43
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.102090 (rank : 32)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	206	Shared Neighborhood Hits	42
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRIM9_HUMAN
NC score	0.094101 (rank : 33)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	294	Shared Neighborhood Hits	43
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

RN185_HUMAN
NC score	0.092590 (rank : 34)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	48
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRIM9_MOUSE
NC score	0.092338 (rank : 35)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	274	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RN185_MOUSE
NC score	0.092028 (rank : 36)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI36_HUMAN
NC score	0.085336 (rank : 37)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	282	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM7_MOUSE
NC score	0.082380 (rank : 38)	θ value	0.00175202 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	358	Shared Neighborhood Hits	51
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI10_MOUSE
NC score	0.081148 (rank : 39)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI40_HUMAN
NC score	0.080970 (rank : 40)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	279	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI36_MOUSE
NC score	0.078252 (rank : 41)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI10_HUMAN
NC score	0.075631 (rank : 42)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	315	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI62_MOUSE
NC score	0.069756 (rank : 43)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	478	Shared Neighborhood Hits	54
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI22_HUMAN
NC score	0.069437 (rank : 44)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

ZN179_HUMAN
NC score	0.068924 (rank : 45)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI52_HUMAN
NC score	0.068622 (rank : 46)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI62_HUMAN
NC score	0.067460 (rank : 47)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	584	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRAF6_MOUSE
NC score	0.066925 (rank : 48)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI68_MOUSE
NC score	0.066719 (rank : 49)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	356	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

FBX43_MOUSE
NC score	0.066618 (rank : 50)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

TRIM6_HUMAN
NC score	0.066157 (rank : 51)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	412	Shared Neighborhood Hits	49
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI26_MOUSE
NC score	0.065171 (rank : 52)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	339	Shared Neighborhood Hits	54
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRIM7_HUMAN
NC score	0.065042 (rank : 53)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	336	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI26_HUMAN
NC score	0.064581 (rank : 54)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	335	Shared Neighborhood Hits	56
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRAF6_HUMAN
NC score	0.064524 (rank : 55)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	267	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI55_HUMAN
NC score	0.064139 (rank : 56)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	292	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI35_HUMAN
NC score	0.064053 (rank : 57)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRIM3_HUMAN
NC score	0.063952 (rank : 58)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	113	Target Neighborhood Hits	357	Shared Neighborhood Hits	58
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI68_HUMAN
NC score	0.063755 (rank : 59)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	267	Shared Neighborhood Hits	47
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI46_MOUSE
NC score	0.062156 (rank : 60)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	287	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM6_MOUSE
NC score	0.061918 (rank : 61)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	451	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI30_MOUSE
NC score	0.061570 (rank : 62)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	434	Shared Neighborhood Hits	53
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI46_HUMAN
NC score	0.061039 (rank : 63)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	291	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM2_HUMAN
NC score	0.060543 (rank : 64)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	113	Target Neighborhood Hits	330	Shared Neighborhood Hits	60
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM3_MOUSE
NC score	0.060509 (rank : 65)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	113	Target Neighborhood Hits	351	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM2_MOUSE
NC score	0.059854 (rank : 66)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	113	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

HECD3_MOUSE
NC score	0.059404 (rank : 67)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.059342 (rank : 68)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	113	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

TRI41_HUMAN
NC score	0.058962 (rank : 69)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	349	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM5_HUMAN
NC score	0.057805 (rank : 70)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	113	Target Neighborhood Hits	424	Shared Neighborhood Hits	52
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RNF4_HUMAN
NC score	0.056730 (rank : 71)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	113	Target Neighborhood Hits	212	Shared Neighborhood Hits	43
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI31_HUMAN
NC score	0.056566 (rank : 72)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	113	Target Neighborhood Hits	299	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI25_HUMAN
NC score	0.056505 (rank : 73)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	472	Shared Neighborhood Hits	56
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI50_MOUSE
NC score	0.056374 (rank : 74)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	113	Target Neighborhood Hits	326	Shared Neighborhood Hits	48
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI35_MOUSE
NC score	0.056276 (rank : 75)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	113	Target Neighborhood Hits	465	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI38_HUMAN
NC score	0.055908 (rank : 76)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	113	Target Neighborhood Hits	373	Shared Neighborhood Hits	51
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI32_HUMAN
NC score	0.055672 (rank : 77)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	113	Target Neighborhood Hits	264	Shared Neighborhood Hits	50
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI27_HUMAN
NC score	0.055060 (rank : 78)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	113	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

RO52_MOUSE
NC score	0.054787 (rank : 79)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	113	Target Neighborhood Hits	360	Shared Neighborhood Hits	50
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI60_HUMAN
NC score	0.054651 (rank : 80)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	357	Shared Neighborhood Hits	51
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

FBX43_HUMAN
NC score	0.054603 (rank : 81)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	9
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

TRI27_MOUSE
NC score	0.054195 (rank : 82)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	113	Target Neighborhood Hits	261	Shared Neighborhood Hits	50
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

RNF4_MOUSE
NC score	0.054148 (rank : 83)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	113	Target Neighborhood Hits	212	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI15_HUMAN
NC score	0.053774 (rank : 84)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	113	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI50_HUMAN
NC score	0.053688 (rank : 85)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	113	Target Neighborhood Hits	294	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RNF39_HUMAN
NC score	0.053656 (rank : 86)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	200	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI17_HUMAN
NC score	0.053556 (rank : 87)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	318	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM8_MOUSE
NC score	0.053060 (rank : 88)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	113	Target Neighborhood Hits	674	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI13_HUMAN
NC score	0.052739 (rank : 89)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	113	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI59_MOUSE
NC score	0.052718 (rank : 90)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	113	Target Neighborhood Hits	292	Shared Neighborhood Hits	49
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.052582 (rank : 91)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	113	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI13_MOUSE
NC score	0.052535 (rank : 92)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	113	Target Neighborhood Hits	282	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRIM1_HUMAN
NC score	0.052533 (rank : 93)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	113	Target Neighborhood Hits	345	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI39_HUMAN
NC score	0.052493 (rank : 94)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	693	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI73_HUMAN
NC score	0.052237 (rank : 95)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM8_HUMAN
NC score	0.052184 (rank : 96)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	113	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI34_HUMAN
NC score	0.052044 (rank : 97)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	113	Target Neighborhood Hits	416	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RO52_HUMAN
NC score	0.052013 (rank : 98)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	113	Target Neighborhood Hits	419	Shared Neighborhood Hits	55
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI74_HUMAN
NC score	0.051738 (rank : 99)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	113	Target Neighborhood Hits	249	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI39_MOUSE
NC score	0.051629 (rank : 100)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	113	Target Neighborhood Hits	691	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI65_HUMAN
NC score	0.051251 (rank : 101)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	113	Target Neighborhood Hits	330	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM4_HUMAN
NC score	0.051020 (rank : 102)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	113	Target Neighborhood Hits	321	Shared Neighborhood Hits	48
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI11_HUMAN
NC score	0.051010 (rank : 103)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	113	Target Neighborhood Hits	316	Shared Neighborhood Hits	45
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI56_MOUSE
NC score	0.050973 (rank : 104)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI12_MOUSE
NC score	0.050950 (rank : 105)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	113	Target Neighborhood Hits	387	Shared Neighborhood Hits	44
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM1_MOUSE
NC score	0.050683 (rank : 106)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	113	Target Neighborhood Hits	361	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI32_MOUSE
NC score	0.050426 (rank : 107)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	113	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI17_MOUSE
NC score	0.050382 (rank : 108)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	113	Target Neighborhood Hits	620	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

R113A_HUMAN
NC score	0.045285 (rank : 109)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

GOLI_HUMAN
NC score	0.044774 (rank : 110)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

BRAP_MOUSE
NC score	0.040340 (rank : 111)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	409	Shared Neighborhood Hits	30
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CQ050_MOUSE
NC score	0.038516 (rank : 112)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C1R3, Q9DAI8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50 homolog.

RN122_HUMAN
NC score	0.037849 (rank : 113)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

PML_MOUSE
NC score	0.036730 (rank : 114)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

BRAP_HUMAN
NC score	0.035813 (rank : 115)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

CQ050_HUMAN
NC score	0.035759 (rank : 116)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WW18, Q6Q621	Gene names	C17orf50
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50.

MKRN3_HUMAN
NC score	0.034657 (rank : 117)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RIMS1_HUMAN
NC score	0.034620 (rank : 118)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	437	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RN122_MOUSE
NC score	0.032705 (rank : 119)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

DZIP3_MOUSE
NC score	0.030966 (rank : 120)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	414	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

CNOT4_HUMAN
NC score	0.030869 (rank : 121)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	15
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
NC score	0.029500 (rank : 122)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	277	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

MLL4_HUMAN
NC score	0.025715 (rank : 123)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	722	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MATR3_HUMAN
NC score	0.024861 (rank : 124)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MLL2_HUMAN
NC score	0.020377 (rank : 125)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	1788	Shared Neighborhood Hits	22
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MATR3_MOUSE
NC score	0.018773 (rank : 126)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

SEC63_MOUSE
NC score	0.016441 (rank : 127)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	601	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

LDLR_MOUSE
NC score	0.012930 (rank : 128)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	382	Shared Neighborhood Hits	9
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

VLDLR_HUMAN
NC score	0.012801 (rank : 129)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP8_MOUSE
NC score	0.012063 (rank : 130)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	385	Shared Neighborhood Hits	10
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SMG1_MOUSE
NC score	0.011738 (rank : 131)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SMG1_HUMAN
NC score	0.011623 (rank : 132)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	231	Shared Neighborhood Hits	5
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

PCSK5_MOUSE
NC score	0.011353 (rank : 133)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	613	Shared Neighborhood Hits	16
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

VLDLR_MOUSE
NC score	0.011022 (rank : 134)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	360	Shared Neighborhood Hits	11
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_HUMAN
NC score	0.010904 (rank : 135)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PRD14_HUMAN
NC score	0.009359 (rank : 136)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	757	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

PRLC2_MOUSE
NC score	0.009302 (rank : 137)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQ58	Gene names	Prlpc2
Domain Architecture	No domain graphic available
Description	Placental prolactin-like protein C2 precursor (PRL-like protein C2) (PLP-C2) (Prolactin-like protein C-beta) (PLP C-beta).

ATS20_MOUSE
NC score	0.009103 (rank : 138)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

STAB2_HUMAN
NC score	0.008493 (rank : 139)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ATS9_HUMAN
NC score	0.007646 (rank : 140)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ZFP95_MOUSE
NC score	0.007208 (rank : 141)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	787	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1D8	Gene names	Zfp95
Domain Architecture
Description	Zinc finger protein 95 (Zfp-95).

CYLN2_HUMAN
NC score	0.005066 (rank : 142)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	1004	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

ATS7_HUMAN
NC score	0.004514 (rank : 143)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ZN260_MOUSE
NC score	0.003980 (rank : 144)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	765	Shared Neighborhood Hits	13
SwissProt Accessions	Q62513, Q3U170, Q8C2Q6, Q9R2B4	Gene names	Znf260, Zfp260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

ZN615_HUMAN
NC score	0.003650 (rank : 145)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	775	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

ZN605_HUMAN
NC score	0.003598 (rank : 146)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	753	Shared Neighborhood Hits	14
SwissProt Accessions	Q86T29, Q86T91	Gene names	ZNF605
Domain Architecture	No domain graphic available
Description	Zinc finger protein 605.

ZNF91_HUMAN
NC score	0.003331 (rank : 147)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	797	Shared Neighborhood Hits	14
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

ZIM3_HUMAN
NC score	0.003299 (rank : 148)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	765	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PE6	Gene names	ZIM3
Domain Architecture
Description	Zinc finger imprinted 3.

FLIP1_MOUSE
NC score	0.003295 (rank : 149)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	1176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ZNF26_HUMAN
NC score	0.003257 (rank : 150)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	736	Shared Neighborhood Hits	14
SwissProt Accessions	P17031, Q9NWL3	Gene names	ZNF26, KOX20
Domain Architecture	No domain graphic available
Description	Zinc finger protein 26 (Zinc finger protein KOX20).

ZN649_HUMAN
NC score	0.003020 (rank : 151)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	745	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BS31, Q9H9N2	Gene names	ZNF649
Domain Architecture	No domain graphic available
Description	Zinc finger protein 649.

VEZF1_HUMAN
NC score	0.002768 (rank : 152)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	744	Shared Neighborhood Hits	14
SwissProt Accessions	Q14119	Gene names	VEZF1, DB1, ZNF161
Domain Architecture	No domain graphic available
Description	Vascular endothelial zinc finger 1 (Zinc finger protein 161) (Putative transcription factor DB1).

ZN510_HUMAN
NC score	0.002668 (rank : 153)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	764	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2H8	Gene names	ZNF510, KIAA0972
Domain Architecture
Description	Zinc finger protein 510.

FLIP1_HUMAN
NC score	0.002498 (rank : 154)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	1405	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).