Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CUL3_HUMAN

For an explanation of this page, click here

CUL3_HUMAN
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CUL3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_MOUSE
θ value	0 (rank : 2)	NC score	0.999748 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL4B_HUMAN
θ value	1.86219e-138 (rank : 3)	NC score	0.956849 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL4A_MOUSE
θ value	2.4321e-138 (rank : 4)	NC score	0.960081 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4A_HUMAN
θ value	3.51195e-137 (rank : 5)	NC score	0.958609 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	40	Shared Neighborhood Hits	14
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

CUL1_HUMAN
θ value	9.035e-101 (rank : 6)	NC score	0.937560 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
θ value	9.035e-101 (rank : 7)	NC score	0.937553 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL2_HUMAN
θ value	8.20983e-86 (rank : 8)	NC score	0.931961 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q13617, O00200, Q9UNF9	Gene names	CUL2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL2_MOUSE
θ value	3.56943e-81 (rank : 9)	NC score	0.930688 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL5_HUMAN
θ value	1.96772e-63 (rank : 10)	NC score	0.904227 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).

CUL5_MOUSE
θ value	2.84138e-62 (rank : 11)	NC score	0.904197 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D5V5, Q8BMQ6, Q8BV53, Q8C098	Gene names	Cul5
Domain Architecture
Description	Cullin-5 (CUL-5).

CJ046_HUMAN
θ value	2.88788e-06 (rank : 12)	NC score	0.200469 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q86Y37, Q5XPL7, Q8IY11, Q8N7S4	Gene names	C10orf46
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46.

CJ046_MOUSE
θ value	2.88788e-06 (rank : 13)	NC score	0.201555 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0X2, Q3TE79, Q9CY95	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46 homolog.

ANC2_MOUSE
θ value	0.000461057 (rank : 14)	NC score	0.387226 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZQ7, Q8R2Q1	Gene names	Anapc2
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANC2_HUMAN
θ value	0.00134147 (rank : 15)	NC score	0.383927 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

PARC_HUMAN
θ value	0.0252991 (rank : 16)	NC score	0.084673 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

A4_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.032957 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	274	Shared Neighborhood Hits	6
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AKAP9_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.016662 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	1710	Shared Neighborhood Hits	22
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

PFTA_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.041096 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49354, Q9UDC1	Gene names	FNTA
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).

GOGA5_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.012526 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	1434	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CTGE2_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.019655 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	594	Shared Neighborhood Hits	12
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

A4_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.027094 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

LAMB1_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.010004 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	1018	Shared Neighborhood Hits	12
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

GOGA3_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.007967 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	1437	Shared Neighborhood Hits	18
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CTGE5_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.011804 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

LAMB1_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.008034 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	919	Shared Neighborhood Hits	12
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NOL8_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.019318 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

SYCP1_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.008566 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	1313	Shared Neighborhood Hits	18
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CAF1A_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.016465 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	750	Shared Neighborhood Hits	12
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.015486 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	736	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ASPP1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.005634 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	956	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CI039_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.007097 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	1171	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CJ118_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.006371 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	937	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CM007_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.012700 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	416	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

NPHP4_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.013941 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	O75161	Gene names	NPHP4, KIAA0673
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

PRKDC_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.009643 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

CLUA1_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.014017 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

COE2_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.004487 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	O08792, Q543D5	Gene names	Ebf2, Coe2, Mmot1
Domain Architecture
Description	Transcription factor COE2 (Early B-cell factor 2) (EBF-2) (Olf-1/EBF- like 3) (OE-3) (O/E-3) (Metencephalon-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory TF1).

DCP1B_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.008389 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

DDX58_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.010721 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

FA21C_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.014238 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

SYCC_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.007661 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P49589, Q53XI8, Q9HD24, Q9HD25	Gene names	CARS
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

CUL7_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.063572 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

PARC_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.055196 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

Hits sorted by NC score

CUL3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_MOUSE
NC score	0.999748 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL4A_MOUSE
NC score	0.960081 (rank : 3)	θ value	2.4321e-138 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4A_HUMAN
NC score	0.958609 (rank : 4)	θ value	3.51195e-137 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	40	Shared Neighborhood Hits	14
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

CUL4B_HUMAN
NC score	0.956849 (rank : 5)	θ value	1.86219e-138 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL1_HUMAN
NC score	0.937560 (rank : 6)	θ value	9.035e-101 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
NC score	0.937553 (rank : 7)	θ value	9.035e-101 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL2_HUMAN
NC score	0.931961 (rank : 8)	θ value	8.20983e-86 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q13617, O00200, Q9UNF9	Gene names	CUL2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL2_MOUSE
NC score	0.930688 (rank : 9)	θ value	3.56943e-81 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL5_HUMAN
NC score	0.904227 (rank : 10)	θ value	1.96772e-63 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).

CUL5_MOUSE
NC score	0.904197 (rank : 11)	θ value	2.84138e-62 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D5V5, Q8BMQ6, Q8BV53, Q8C098	Gene names	Cul5
Domain Architecture
Description	Cullin-5 (CUL-5).

ANC2_MOUSE
NC score	0.387226 (rank : 12)	θ value	0.000461057 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZQ7, Q8R2Q1	Gene names	Anapc2
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANC2_HUMAN
NC score	0.383927 (rank : 13)	θ value	0.00134147 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

CJ046_MOUSE
NC score	0.201555 (rank : 14)	θ value	2.88788e-06 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0X2, Q3TE79, Q9CY95	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46 homolog.

CJ046_HUMAN
NC score	0.200469 (rank : 15)	θ value	2.88788e-06 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q86Y37, Q5XPL7, Q8IY11, Q8N7S4	Gene names	C10orf46
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46.

PARC_HUMAN
NC score	0.084673 (rank : 16)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

CUL7_HUMAN
NC score	0.063572 (rank : 17)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

PARC_MOUSE
NC score	0.055196 (rank : 18)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PFTA_HUMAN
NC score	0.041096 (rank : 19)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49354, Q9UDC1	Gene names	FNTA
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).

A4_HUMAN
NC score	0.032957 (rank : 20)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	274	Shared Neighborhood Hits	6
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
NC score	0.027094 (rank : 21)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CTGE2_HUMAN
NC score	0.019655 (rank : 22)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	594	Shared Neighborhood Hits	12
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

NOL8_MOUSE
NC score	0.019318 (rank : 23)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

AKAP9_HUMAN
NC score	0.016662 (rank : 24)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	1710	Shared Neighborhood Hits	22
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CAF1A_HUMAN
NC score	0.016465 (rank : 25)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	750	Shared Neighborhood Hits	12
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
NC score	0.015486 (rank : 26)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	736	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

FA21C_HUMAN
NC score	0.014238 (rank : 27)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

CLUA1_MOUSE
NC score	0.014017 (rank : 28)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

NPHP4_HUMAN
NC score	0.013941 (rank : 29)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	O75161	Gene names	NPHP4, KIAA0673
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

CM007_MOUSE
NC score	0.012700 (rank : 30)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	416	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

GOGA5_MOUSE
NC score	0.012526 (rank : 31)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	1434	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CTGE5_HUMAN
NC score	0.011804 (rank : 32)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DDX58_HUMAN
NC score	0.010721 (rank : 33)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

LAMB1_HUMAN
NC score	0.010004 (rank : 34)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	1018	Shared Neighborhood Hits	12
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PRKDC_HUMAN
NC score	0.009643 (rank : 35)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

SYCP1_HUMAN
NC score	0.008566 (rank : 36)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	1313	Shared Neighborhood Hits	18
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DCP1B_HUMAN
NC score	0.008389 (rank : 37)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

LAMB1_MOUSE
NC score	0.008034 (rank : 38)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	919	Shared Neighborhood Hits	12
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

GOGA3_MOUSE
NC score	0.007967 (rank : 39)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	1437	Shared Neighborhood Hits	18
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SYCC_HUMAN
NC score	0.007661 (rank : 40)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P49589, Q53XI8, Q9HD24, Q9HD25	Gene names	CARS
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

CI039_HUMAN
NC score	0.007097 (rank : 41)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	1171	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CJ118_HUMAN
NC score	0.006371 (rank : 42)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	937	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

ASPP1_HUMAN
NC score	0.005634 (rank : 43)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	956	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

COE2_MOUSE
NC score	0.004487 (rank : 44)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	O08792, Q543D5	Gene names	Ebf2, Coe2, Mmot1
Domain Architecture
Description	Transcription factor COE2 (Early B-cell factor 2) (EBF-2) (Olf-1/EBF- like 3) (OE-3) (O/E-3) (Metencephalon-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory TF1).