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Network neighborhood for query Sequence : CUL5_HUMAN

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CUL5_HUMAN
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CUL5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).

CUL5_MOUSE
θ value	0 (rank : 2)	NC score	0.999314 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D5V5, Q8BMQ6, Q8BV53, Q8C098	Gene names	Cul5
Domain Architecture
Description	Cullin-5 (CUL-5).

CUL1_MOUSE
θ value	4.96919e-91 (rank : 3)	NC score	0.933431 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_HUMAN
θ value	6.48998e-91 (rank : 4)	NC score	0.933382 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL2_HUMAN
θ value	5.69867e-79 (rank : 5)	NC score	0.928357 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q13617, O00200, Q9UNF9	Gene names	CUL2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL2_MOUSE
θ value	1.89707e-74 (rank : 6)	NC score	0.926619 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL3_HUMAN
θ value	1.96772e-63 (rank : 7)	NC score	0.904227 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_MOUSE
θ value	2.56992e-63 (rank : 8)	NC score	0.904155 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL4B_HUMAN
θ value	1.01059e-59 (rank : 9)	NC score	0.889798 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL4A_MOUSE
θ value	4.69435e-57 (rank : 10)	NC score	0.890929 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4A_HUMAN
θ value	8.00737e-57 (rank : 11)	NC score	0.889418 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

ANC2_MOUSE
θ value	0.00390308 (rank : 12)	NC score	0.363652 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZQ7, Q8R2Q1	Gene names	Anapc2
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANC2_HUMAN
θ value	0.00665767 (rank : 13)	NC score	0.361423 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

NUMA1_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.027933 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	1523	Shared Neighborhood Hits	25
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CYH2_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.025711 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

SYCP1_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.017003 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	1456	Shared Neighborhood Hits	22
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

IFT74_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.024340 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	939	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SMC2_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.018902 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	1405	Shared Neighborhood Hits	23
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CYH2_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.016349 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

KIF4A_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.012912 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	1033	Shared Neighborhood Hits	23
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NOS2_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.017522 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

SMC4_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.023440 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	830	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

IFT74_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.021202 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	949	Shared Neighborhood Hits	21
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

GOGA5_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.016745 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	1434	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

PSMD9_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.020802 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

RB6I2_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.013550 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	1584	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

KIF4A_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.010664 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	1159	Shared Neighborhood Hits	23
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

S10A8_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.025446 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P05109, Q9UC92, Q9UCJ0	Gene names	S100A8, CAGA, MRP8
Domain Architecture
Description	Protein S100-A8 (S100 calcium-binding protein A8) (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (Calprotectin L1L subunit) (Urinary stone protein band A).

SPTN4_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.009636 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	570	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

UTRO_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.013843 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

PHLB1_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.015609 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	1038	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SMC4_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.020016 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	937	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

TRIM7_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.003490 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

AKAP9_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.019212 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	1710	Shared Neighborhood Hits	31
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

DMAP1_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.024367 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NPF5, Q5TG41, Q7Z3H7, Q9H0S8, Q9P2C2	Gene names	DMAP1, KIAA1425
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1).

DMAP1_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.024401 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI44, Q99LM0, Q9CSS9, Q9DB33	Gene names	Dmap1, Mmtr
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1) (MAT1-mediated transcriptional repressor).

MOES_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.008307 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	923	Shared Neighborhood Hits	23
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TPR_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.016543 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	1921	Shared Neighborhood Hits	28
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TTC14_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.022118 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

VP13A_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.019156 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

CENPF_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.011229 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	1932	Shared Neighborhood Hits	26
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CI082_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.010778 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

FMNL_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.005780 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	529	Shared Neighborhood Hits	13
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GDPD4_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.010290 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TT99, Q8BI25	Gene names	Gdpd4, Gde6
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 4 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 6).

RB6I2_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.011939 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	1433	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TS13_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.011537 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

CJ046_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.066510 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y37, Q5XPL7, Q8IY11, Q8N7S4	Gene names	C10orf46
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46.

CJ046_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.067181 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0X2, Q3TE79, Q9CY95	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46 homolog.

CUL7_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.050846 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

Hits sorted by NC score

CUL5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).

CUL5_MOUSE
NC score	0.999314 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D5V5, Q8BMQ6, Q8BV53, Q8C098	Gene names	Cul5
Domain Architecture
Description	Cullin-5 (CUL-5).

CUL1_MOUSE
NC score	0.933431 (rank : 3)	θ value	4.96919e-91 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_HUMAN
NC score	0.933382 (rank : 4)	θ value	6.48998e-91 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL2_HUMAN
NC score	0.928357 (rank : 5)	θ value	5.69867e-79 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q13617, O00200, Q9UNF9	Gene names	CUL2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL2_MOUSE
NC score	0.926619 (rank : 6)	θ value	1.89707e-74 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL3_HUMAN
NC score	0.904227 (rank : 7)	θ value	1.96772e-63 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_MOUSE
NC score	0.904155 (rank : 8)	θ value	2.56992e-63 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL4A_MOUSE
NC score	0.890929 (rank : 9)	θ value	4.69435e-57 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4B_HUMAN
NC score	0.889798 (rank : 10)	θ value	1.01059e-59 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL4A_HUMAN
NC score	0.889418 (rank : 11)	θ value	8.00737e-57 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

ANC2_MOUSE
NC score	0.363652 (rank : 12)	θ value	0.00390308 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZQ7, Q8R2Q1	Gene names	Anapc2
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANC2_HUMAN
NC score	0.361423 (rank : 13)	θ value	0.00665767 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

CJ046_MOUSE
NC score	0.067181 (rank : 14)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0X2, Q3TE79, Q9CY95	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46 homolog.

CJ046_HUMAN
NC score	0.066510 (rank : 15)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y37, Q5XPL7, Q8IY11, Q8N7S4	Gene names	C10orf46
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46.

CUL7_HUMAN
NC score	0.050846 (rank : 16)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

NUMA1_HUMAN
NC score	0.027933 (rank : 17)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	1523	Shared Neighborhood Hits	25
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CYH2_MOUSE
NC score	0.025711 (rank : 18)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

S10A8_HUMAN
NC score	0.025446 (rank : 19)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P05109, Q9UC92, Q9UCJ0	Gene names	S100A8, CAGA, MRP8
Domain Architecture
Description	Protein S100-A8 (S100 calcium-binding protein A8) (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (Calprotectin L1L subunit) (Urinary stone protein band A).

DMAP1_MOUSE
NC score	0.024401 (rank : 20)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI44, Q99LM0, Q9CSS9, Q9DB33	Gene names	Dmap1, Mmtr
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1) (MAT1-mediated transcriptional repressor).

DMAP1_HUMAN
NC score	0.024367 (rank : 21)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NPF5, Q5TG41, Q7Z3H7, Q9H0S8, Q9P2C2	Gene names	DMAP1, KIAA1425
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1).

IFT74_MOUSE
NC score	0.024340 (rank : 22)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	939	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SMC4_MOUSE
NC score	0.023440 (rank : 23)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	830	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TTC14_HUMAN
NC score	0.022118 (rank : 24)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

IFT74_HUMAN
NC score	0.021202 (rank : 25)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	949	Shared Neighborhood Hits	21
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

PSMD9_MOUSE
NC score	0.020802 (rank : 26)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

SMC4_HUMAN
NC score	0.020016 (rank : 27)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	937	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

AKAP9_HUMAN
NC score	0.019212 (rank : 28)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	1710	Shared Neighborhood Hits	31
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

VP13A_HUMAN
NC score	0.019156 (rank : 29)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

SMC2_HUMAN
NC score	0.018902 (rank : 30)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	1405	Shared Neighborhood Hits	23
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

NOS2_MOUSE
NC score	0.017522 (rank : 31)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

SYCP1_MOUSE
NC score	0.017003 (rank : 32)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	1456	Shared Neighborhood Hits	22
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

GOGA5_MOUSE
NC score	0.016745 (rank : 33)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	1434	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TPR_HUMAN
NC score	0.016543 (rank : 34)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	1921	Shared Neighborhood Hits	28
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CYH2_HUMAN
NC score	0.016349 (rank : 35)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

PHLB1_HUMAN
NC score	0.015609 (rank : 36)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	1038	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

UTRO_HUMAN
NC score	0.013843 (rank : 37)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

RB6I2_HUMAN
NC score	0.013550 (rank : 38)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	1584	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

KIF4A_MOUSE
NC score	0.012912 (rank : 39)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	1033	Shared Neighborhood Hits	23
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

RB6I2_MOUSE
NC score	0.011939 (rank : 40)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	1433	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TS13_MOUSE
NC score	0.011537 (rank : 41)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

CENPF_HUMAN
NC score	0.011229 (rank : 42)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	1932	Shared Neighborhood Hits	26
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CI082_HUMAN
NC score	0.010778 (rank : 43)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

KIF4A_HUMAN
NC score	0.010664 (rank : 44)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	1159	Shared Neighborhood Hits	23
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

GDPD4_MOUSE
NC score	0.010290 (rank : 45)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TT99, Q8BI25	Gene names	Gdpd4, Gde6
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 4 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 6).

SPTN4_HUMAN
NC score	0.009636 (rank : 46)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	570	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

MOES_MOUSE
NC score	0.008307 (rank : 47)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	923	Shared Neighborhood Hits	23
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FMNL_HUMAN
NC score	0.005780 (rank : 48)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	529	Shared Neighborhood Hits	13
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TRIM7_HUMAN
NC score	0.003490 (rank : 49)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).