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Network neighborhood for query Sequence : NPTX2_MOUSE

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NPTX2_MOUSE
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NPTX2_HUMAN
θ value	0 (rank : 1)	NC score	0.993224 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	86	Shared Neighborhood Hits	57
SwissProt Accessions	P47972, Q86XV7, Q96G70	Gene names	NPTX2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NPTX2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NPTX1_HUMAN
θ value	1.05987e-125 (rank : 3)	NC score	0.971654 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q15818, Q5FWE6	Gene names	NPTX1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NPTX1_MOUSE
θ value	1.80787e-125 (rank : 4)	NC score	0.970098 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q62443	Gene names	Nptx1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NPTXR_MOUSE
θ value	2.9938e-112 (rank : 5)	NC score	0.961624 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q99J85	Gene names	Nptxr, Npr
Domain Architecture
Description	Neuronal pentraxin receptor.

NPTXR_HUMAN
θ value	1.48581e-111 (rank : 6)	NC score	0.968619 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	O95502	Gene names	NPTXR
Domain Architecture
Description	Neuronal pentraxin receptor.

GP144_HUMAN
θ value	4.73814e-25 (rank : 7)	NC score	0.414169 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

PTX3_MOUSE
θ value	1.6852e-22 (rank : 8)	NC score	0.768967 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P48759, Q8VDF1	Gene names	Ptx3, Tsg14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

PTX3_HUMAN
θ value	1.42661e-21 (rank : 9)	NC score	0.764007 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	P26022	Gene names	PTX3, TSG14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

SAMP_HUMAN
θ value	9.90251e-15 (rank : 10)	NC score	0.692462 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P02743	Gene names	APCS, PTX2
Domain Architecture
Description	Serum amyloid P-component precursor (SAP) (9.5S alpha-1-glycoprotein) [Contains: Serum amyloid P-component(1-203)].

SAMP_MOUSE
θ value	2.20605e-14 (rank : 11)	NC score	0.690385 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P12246	Gene names	Apcs, Ptx2, Sap
Domain Architecture
Description	Serum amyloid P-component precursor (SAP).

CRP_MOUSE
θ value	6.41864e-14 (rank : 12)	NC score	0.703262 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	P14847	Gene names	Crp, Ptx1
Domain Architecture
Description	C-reactive protein precursor.

CRP_HUMAN
θ value	8.38298e-14 (rank : 13)	NC score	0.698548 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	P02741, Q8WW75	Gene names	CRP, PTX1
Domain Architecture
Description	C-reactive protein precursor [Contains: C-reactive protein(1-205)].

GP112_HUMAN
θ value	0.000158464 (rank : 14)	NC score	0.112242 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	441	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TRI38_HUMAN
θ value	0.00390308 (rank : 15)	NC score	0.022011 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	373	Shared Neighborhood Hits	18
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

MYOC_HUMAN
θ value	0.0252991 (rank : 16)	NC score	0.051531 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	489	Shared Neighborhood Hits	33
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

GCC2_MOUSE
θ value	0.0431538 (rank : 17)	NC score	0.046158 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	1619	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CENPF_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.048300 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	1932	Shared Neighborhood Hits	58
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF060_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.047105 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	1270	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MYH9_MOUSE
θ value	0.0961366 (rank : 20)	NC score	0.036898 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	1829	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CCD46_MOUSE
θ value	0.125558 (rank : 21)	NC score	0.039575 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	1405	Shared Neighborhood Hits	50
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

MYH9_HUMAN
θ value	0.125558 (rank : 22)	NC score	0.035977 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	1762	Shared Neighborhood Hits	57
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CP250_MOUSE
θ value	0.21417 (rank : 23)	NC score	0.044985 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	1583	Shared Neighborhood Hits	53
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GFAP_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.030859 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	723	Shared Neighborhood Hits	43
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

EMIL2_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.035994 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	485	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

TAXB1_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.037159 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

DDIT3_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.055777 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

GFAP_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.028616 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	725	Shared Neighborhood Hits	45
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GP126_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.070040 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

VDP_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.039953 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

KGP2_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.005217 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	1023	Shared Neighborhood Hits	17
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

CROCC_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.044059 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	1409	Shared Neighborhood Hits	56
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CTTB2_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.018901 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	1061	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

HOME3_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.026173 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	275	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

RB6I2_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.034917 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	1584	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

GCC2_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.042909 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	1558	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.042968 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	1559	Shared Neighborhood Hits	52
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

TLK2_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.003988 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	1044	Shared Neighborhood Hits	23
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

DOCK6_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.015617 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

FARP2_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.009398 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

KINH_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.027023 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	1231	Shared Neighborhood Hits	47
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

REST_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.033277 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	1506	Shared Neighborhood Hits	51
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ANR25_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.010083 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	350	Shared Neighborhood Hits	4
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

CCD39_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.035846 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	868	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CENPE_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.029090 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ANR25_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.009409 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	398	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CCD46_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.035755 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	1430	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CNTP4_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.010336 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

FNBP2_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.017395 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	432	Shared Neighborhood Hits	27
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

KGP2_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.003619 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	1029	Shared Neighborhood Hits	20
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KRHB1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.023840 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	461	Shared Neighborhood Hits	35
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB3_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.023351 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	438	Shared Neighborhood Hits	35
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

KRHB6_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.023905 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	447	Shared Neighborhood Hits	36
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

KRHB6_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.021093 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	413	Shared Neighborhood Hits	33
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

MACOI_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.029942 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MATN4_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.003016 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PCNT_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.044959 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	1551	Shared Neighborhood Hits	57
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RIMB1_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.027464 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	1376	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ROCK2_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.014198 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	2073	Shared Neighborhood Hits	49
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SDCG8_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.033678 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	886	Shared Neighborhood Hits	39
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SPAG5_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.037388 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	625	Shared Neighborhood Hits	38
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TENA_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.002346 (rank : 80)
Query Neighborhood Hits	79	Target Neighborhood Hits	631	Shared Neighborhood Hits	4
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TRIM3_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.014280 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	357	Shared Neighborhood Hits	11
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

GOG8A_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.029361 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	635	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

HMMR_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.031021 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	1178	Shared Neighborhood Hits	41
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IDLC_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.023257 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	348	Shared Neighborhood Hits	24
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

LAMB2_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.007754 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LRRF2_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.032672 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

RUSC2_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.008973 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SRGP2_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.016828 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	324	Shared Neighborhood Hits	18
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SYNE2_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.026494 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	1323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CCD21_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.026619 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	1228	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CNTP4_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.008664 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

KRHB5_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.018035 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	294	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

MYH11_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.033405 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	1806	Shared Neighborhood Hits	53
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NFH_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.021017 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	1242	Shared Neighborhood Hits	40
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ROCK2_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.015373 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	2072	Shared Neighborhood Hits	49
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SRGP2_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.013938 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

ST18_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.013721 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	252	Shared Neighborhood Hits	23
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

GP133_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.067198 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

Hits sorted by NC score

NPTX2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NPTX2_HUMAN
NC score	0.993224 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	86	Shared Neighborhood Hits	57
SwissProt Accessions	P47972, Q86XV7, Q96G70	Gene names	NPTX2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

NPTX1_HUMAN
NC score	0.971654 (rank : 3)	θ value	1.05987e-125 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q15818, Q5FWE6	Gene names	NPTX1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NPTX1_MOUSE
NC score	0.970098 (rank : 4)	θ value	1.80787e-125 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q62443	Gene names	Nptx1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NPTXR_HUMAN
NC score	0.968619 (rank : 5)	θ value	1.48581e-111 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	O95502	Gene names	NPTXR
Domain Architecture
Description	Neuronal pentraxin receptor.

NPTXR_MOUSE
NC score	0.961624 (rank : 6)	θ value	2.9938e-112 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q99J85	Gene names	Nptxr, Npr
Domain Architecture
Description	Neuronal pentraxin receptor.

PTX3_MOUSE
NC score	0.768967 (rank : 7)	θ value	1.6852e-22 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P48759, Q8VDF1	Gene names	Ptx3, Tsg14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

PTX3_HUMAN
NC score	0.764007 (rank : 8)	θ value	1.42661e-21 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	P26022	Gene names	PTX3, TSG14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

CRP_MOUSE
NC score	0.703262 (rank : 9)	θ value	6.41864e-14 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	P14847	Gene names	Crp, Ptx1
Domain Architecture
Description	C-reactive protein precursor.

CRP_HUMAN
NC score	0.698548 (rank : 10)	θ value	8.38298e-14 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	P02741, Q8WW75	Gene names	CRP, PTX1
Domain Architecture
Description	C-reactive protein precursor [Contains: C-reactive protein(1-205)].

SAMP_HUMAN
NC score	0.692462 (rank : 11)	θ value	9.90251e-15 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P02743	Gene names	APCS, PTX2
Domain Architecture
Description	Serum amyloid P-component precursor (SAP) (9.5S alpha-1-glycoprotein) [Contains: Serum amyloid P-component(1-203)].

SAMP_MOUSE
NC score	0.690385 (rank : 12)	θ value	2.20605e-14 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P12246	Gene names	Apcs, Ptx2, Sap
Domain Architecture
Description	Serum amyloid P-component precursor (SAP).

GP144_HUMAN
NC score	0.414169 (rank : 13)	θ value	4.73814e-25 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP112_HUMAN
NC score	0.112242 (rank : 14)	θ value	0.000158464 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	441	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP126_HUMAN
NC score	0.070040 (rank : 15)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP133_HUMAN
NC score	0.067198 (rank : 16)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	79	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

DDIT3_HUMAN
NC score	0.055777 (rank : 17)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

MYOC_HUMAN
NC score	0.051531 (rank : 18)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	489	Shared Neighborhood Hits	33
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

CENPF_HUMAN
NC score	0.048300 (rank : 19)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	1932	Shared Neighborhood Hits	58
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF060_HUMAN
NC score	0.047105 (rank : 20)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	1270	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

GCC2_MOUSE
NC score	0.046158 (rank : 21)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	1619	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CP250_MOUSE
NC score	0.044985 (rank : 22)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	1583	Shared Neighborhood Hits	53
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

PCNT_HUMAN
NC score	0.044959 (rank : 23)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	1551	Shared Neighborhood Hits	57
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CROCC_HUMAN
NC score	0.044059 (rank : 24)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	1409	Shared Neighborhood Hits	56
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RBP24_HUMAN
NC score	0.042968 (rank : 25)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	1559	Shared Neighborhood Hits	52
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.042909 (rank : 26)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	1558	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

VDP_HUMAN
NC score	0.039953 (rank : 27)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CCD46_MOUSE
NC score	0.039575 (rank : 28)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	1405	Shared Neighborhood Hits	50
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

SPAG5_HUMAN
NC score	0.037388 (rank : 29)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	625	Shared Neighborhood Hits	38
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TAXB1_MOUSE
NC score	0.037159 (rank : 30)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

MYH9_MOUSE
NC score	0.036898 (rank : 31)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	1829	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

EMIL2_MOUSE
NC score	0.035994 (rank : 32)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	485	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

MYH9_HUMAN
NC score	0.035977 (rank : 33)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	1762	Shared Neighborhood Hits	57
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CCD39_HUMAN
NC score	0.035846 (rank : 34)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	868	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD46_HUMAN
NC score	0.035755 (rank : 35)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	1430	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

RB6I2_HUMAN
NC score	0.034917 (rank : 36)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	1584	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SDCG8_MOUSE
NC score	0.033678 (rank : 37)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	886	Shared Neighborhood Hits	39
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

MYH11_HUMAN
NC score	0.033405 (rank : 38)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	1806	Shared Neighborhood Hits	53
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

REST_MOUSE
NC score	0.033277 (rank : 39)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	1506	Shared Neighborhood Hits	51
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

LRRF2_MOUSE
NC score	0.032672 (rank : 40)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

HMMR_MOUSE
NC score	0.031021 (rank : 41)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	1178	Shared Neighborhood Hits	41
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GFAP_HUMAN
NC score	0.030859 (rank : 42)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	723	Shared Neighborhood Hits	43
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

MACOI_HUMAN
NC score	0.029942 (rank : 43)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

GOG8A_HUMAN
NC score	0.029361 (rank : 44)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	635	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

CENPE_HUMAN
NC score	0.029090 (rank : 45)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GFAP_MOUSE
NC score	0.028616 (rank : 46)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	725	Shared Neighborhood Hits	45
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

RIMB1_MOUSE
NC score	0.027464 (rank : 47)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	1376	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

KINH_HUMAN
NC score	0.027023 (rank : 48)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	1231	Shared Neighborhood Hits	47
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CCD21_HUMAN
NC score	0.026619 (rank : 49)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	1228	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SYNE2_HUMAN
NC score	0.026494 (rank : 50)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	1323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

HOME3_HUMAN
NC score	0.026173 (rank : 51)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	275	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

KRHB6_HUMAN
NC score	0.023905 (rank : 52)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	447	Shared Neighborhood Hits	36
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

KRHB1_HUMAN
NC score	0.023840 (rank : 53)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	461	Shared Neighborhood Hits	35
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB3_HUMAN
NC score	0.023351 (rank : 54)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	438	Shared Neighborhood Hits	35
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

IDLC_HUMAN
NC score	0.023257 (rank : 55)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	348	Shared Neighborhood Hits	24
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

TRI38_HUMAN
NC score	0.022011 (rank : 56)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	373	Shared Neighborhood Hits	18
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

KRHB6_MOUSE
NC score	0.021093 (rank : 57)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	413	Shared Neighborhood Hits	33
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

NFH_HUMAN
NC score	0.021017 (rank : 58)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	1242	Shared Neighborhood Hits	40
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CTTB2_HUMAN
NC score	0.018901 (rank : 59)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	1061	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

KRHB5_MOUSE
NC score	0.018035 (rank : 60)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	294	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

FNBP2_HUMAN
NC score	0.017395 (rank : 61)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	432	Shared Neighborhood Hits	27
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SRGP2_MOUSE
NC score	0.016828 (rank : 62)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	324	Shared Neighborhood Hits	18
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

DOCK6_HUMAN
NC score	0.015617 (rank : 63)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

ROCK2_MOUSE
NC score	0.015373 (rank : 64)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	2072	Shared Neighborhood Hits	49
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TRIM3_HUMAN
NC score	0.014280 (rank : 65)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	357	Shared Neighborhood Hits	11
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

ROCK2_HUMAN
NC score	0.014198 (rank : 66)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	2073	Shared Neighborhood Hits	49
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SRGP2_HUMAN
NC score	0.013938 (rank : 67)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

ST18_HUMAN
NC score	0.013721 (rank : 68)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	252	Shared Neighborhood Hits	23
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

CNTP4_HUMAN
NC score	0.010336 (rank : 69)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ANR25_HUMAN
NC score	0.010083 (rank : 70)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	350	Shared Neighborhood Hits	4
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR25_MOUSE
NC score	0.009409 (rank : 71)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	398	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

FARP2_MOUSE
NC score	0.009398 (rank : 72)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

RUSC2_HUMAN
NC score	0.008973 (rank : 73)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CNTP4_MOUSE
NC score	0.008664 (rank : 74)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

LAMB2_MOUSE
NC score	0.007754 (rank : 75)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

KGP2_HUMAN
NC score	0.005217 (rank : 76)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	1023	Shared Neighborhood Hits	17
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

TLK2_HUMAN
NC score	0.003988 (rank : 77)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	1044	Shared Neighborhood Hits	23
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

KGP2_MOUSE
NC score	0.003619 (rank : 78)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	1029	Shared Neighborhood Hits	20
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

MATN4_MOUSE
NC score	0.003016 (rank : 79)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

TENA_HUMAN
NC score	0.002346 (rank : 80)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	631	Shared Neighborhood Hits	4
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).