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Network neighborhood for query Sequence : NCOA4_HUMAN

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NCOA4_HUMAN
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NCOA4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).

STK10_HUMAN
θ value	0.125558 (rank : 2)	NC score	0.020056 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	1921	Shared Neighborhood Hits	5
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
θ value	0.125558 (rank : 3)	NC score	0.019865 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	2132	Shared Neighborhood Hits	5
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

RBM19_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.055002 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

ANR11_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.029796 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	1289	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

DMXL2_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.043129 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	374	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

GSHB_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.060946 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P48637, Q4TTD9	Gene names	GSS
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

RBM19_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.048049 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	296	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

TRAF5_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.022316 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	396	Shared Neighborhood Hits	3
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

ITB1_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.013413 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	298	Shared Neighborhood Hits	2
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TRIM3_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.021789 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

ZN250_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.004222 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	756	Shared Neighborhood Hits	4
SwissProt Accessions	P15622, Q8N942, Q96AH9	Gene names	ZNF250, ZNF647
Domain Architecture	No domain graphic available
Description	Zinc finger protein 250 (Zinc finger protein 647).

TRIM3_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.020770 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

ZN431_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.003704 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	765	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF32, Q8IWC4	Gene names	ZNF431, KIAA1969
Domain Architecture
Description	Zinc finger protein 431.

DEK_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.025463 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

ZN250_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.003715 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	773	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TNU6, Q8BJ57	Gene names	Znf250, Zfp647, Znf647
Domain Architecture	No domain graphic available
Description	Zinc finger protein 250 (Zinc finger protein 647).

ASXL1_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.018671 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	182	Shared Neighborhood Hits	2
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

USP9X_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.016513 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.016590 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

Hits sorted by NC score

NCOA4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).

GSHB_HUMAN
NC score	0.060946 (rank : 2)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P48637, Q4TTD9	Gene names	GSS
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

RBM19_HUMAN
NC score	0.055002 (rank : 3)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RBM19_MOUSE
NC score	0.048049 (rank : 4)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	296	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

DMXL2_HUMAN
NC score	0.043129 (rank : 5)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	374	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

ANR11_HUMAN
NC score	0.029796 (rank : 6)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	1289	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

DEK_MOUSE
NC score	0.025463 (rank : 7)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TRAF5_HUMAN
NC score	0.022316 (rank : 8)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	396	Shared Neighborhood Hits	3
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRIM3_HUMAN
NC score	0.021789 (rank : 9)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
NC score	0.020770 (rank : 10)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

STK10_HUMAN
NC score	0.020056 (rank : 11)	θ value	0.125558 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	1921	Shared Neighborhood Hits	5
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
NC score	0.019865 (rank : 12)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	2132	Shared Neighborhood Hits	5
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ASXL1_MOUSE
NC score	0.018671 (rank : 13)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	182	Shared Neighborhood Hits	2
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

USP9X_MOUSE
NC score	0.016590 (rank : 14)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9X_HUMAN
NC score	0.016513 (rank : 15)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

ITB1_HUMAN
NC score	0.013413 (rank : 16)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	298	Shared Neighborhood Hits	2
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ZN250_HUMAN
NC score	0.004222 (rank : 17)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	756	Shared Neighborhood Hits	4
SwissProt Accessions	P15622, Q8N942, Q96AH9	Gene names	ZNF250, ZNF647
Domain Architecture	No domain graphic available
Description	Zinc finger protein 250 (Zinc finger protein 647).

ZN250_MOUSE
NC score	0.003715 (rank : 18)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	773	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TNU6, Q8BJ57	Gene names	Znf250, Zfp647, Znf647
Domain Architecture	No domain graphic available
Description	Zinc finger protein 250 (Zinc finger protein 647).

ZN431_HUMAN
NC score	0.003704 (rank : 19)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	765	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF32, Q8IWC4	Gene names	ZNF431, KIAA1969
Domain Architecture
Description	Zinc finger protein 431.