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Network neighborhood for query Sequence : OSB11_HUMAN

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OSB11_HUMAN
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSB10_HUMAN
θ value	0 (rank : 1)	NC score	0.985121 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_MOUSE
θ value	0 (rank : 3)	NC score	0.997730 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	71	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
θ value	1.09934e-114 (rank : 4)	NC score	0.946057 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL8_HUMAN
θ value	5.73848e-55 (rank : 5)	NC score	0.821889 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL5_HUMAN
θ value	2.94719e-51 (rank : 6)	NC score	0.835616 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	8.57503e-51 (rank : 7)	NC score	0.839762 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	77	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL1_HUMAN
θ value	8.36355e-22 (rank : 8)	NC score	0.482895 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	368	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	1.42661e-21 (rank : 9)	NC score	0.495589 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	336	Shared Neighborhood Hits	27
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBP1_HUMAN
θ value	4.15078e-21 (rank : 10)	NC score	0.683649 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL2_MOUSE
θ value	5.60996e-18 (rank : 11)	NC score	0.692863 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP2_HUMAN
θ value	9.56915e-18 (rank : 12)	NC score	0.674134 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBL2_HUMAN
θ value	1.63225e-17 (rank : 13)	NC score	0.690645 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL7_HUMAN
θ value	1.52774e-15 (rank : 14)	NC score	0.651721 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBP2_MOUSE
θ value	7.58209e-15 (rank : 15)	NC score	0.651702 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	150	Shared Neighborhood Hits	35
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL6_HUMAN
θ value	9.90251e-15 (rank : 16)	NC score	0.633023 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
θ value	1.42992e-13 (rank : 17)	NC score	0.628636 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_MOUSE
θ value	7.84624e-12 (rank : 18)	NC score	0.617565 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

C43BP_HUMAN
θ value	4.30538e-10 (rank : 19)	NC score	0.462027 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	87	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
θ value	5.62301e-10 (rank : 20)	NC score	0.457176 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBL3_HUMAN
θ value	5.62301e-10 (rank : 21)	NC score	0.608482 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKHA3_HUMAN
θ value	1.99992e-07 (rank : 22)	NC score	0.488577 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	2.61198e-07 (rank : 23)	NC score	0.494081 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

RHG25_MOUSE
θ value	9.29e-05 (rank : 24)	NC score	0.136245 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	492	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PLEK_MOUSE
θ value	0.000121331 (rank : 25)	NC score	0.223566 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RHG25_HUMAN
θ value	0.00020696 (rank : 26)	NC score	0.134994 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	550	Shared Neighborhood Hits	37
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PLEK_HUMAN
θ value	0.00035302 (rank : 27)	NC score	0.213932 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	110	Shared Neighborhood Hits	30
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

GNRP_HUMAN
θ value	0.00298849 (rank : 28)	NC score	0.092706 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	239	Shared Neighborhood Hits	26
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

PLEK2_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.215772 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	101	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	0.00509761 (rank : 30)	NC score	0.219522 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

GNRP_MOUSE
θ value	0.0252991 (rank : 31)	NC score	0.077655 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	191	Shared Neighborhood Hits	23
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CYH4_HUMAN
θ value	0.0330416 (rank : 32)	NC score	0.115521 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

SWP70_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.132722 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	973	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.128242 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	1097	Shared Neighborhood Hits	37
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA6_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.115792 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	556	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MTMRD_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.114688 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA6_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.108137 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	591	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CYH4_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.113169 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

UBP47_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.027393 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

CJ084_MOUSE
θ value	0.813845 (rank : 40)	NC score	0.039387 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C6C7	Gene names	D19Ertd737e
Domain Architecture	No domain graphic available
Description	Protein C10orf84 homolog.

MTMR5_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.072974 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

ODPAT_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.023075 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P29803	Gene names	PDHA2
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II).

CAPS1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.028087 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.027468 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

PKHA2_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.081004 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

SPTB2_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.012401 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	748	Shared Neighborhood Hits	20
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

CENG3_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.016637 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	455	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.014971 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CROCC_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.004361 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	1409	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

APS_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.017452 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.018729 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CJ084_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.028725 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8W3, Q9H5V5	Gene names	C10orf84
Domain Architecture	No domain graphic available
Description	Protein C10orf84.

K1914_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.029553 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

MPP8_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.014200 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	948	Shared Neighborhood Hits	7
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OS9_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.033004 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

K1914_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.030193 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

NKTR_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.002630 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	658	Shared Neighborhood Hits	3
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

KLHL4_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.000587 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

SLIK2_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.006173 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H156, Q5JXB1, Q8NBC7, Q96JH3	Gene names	SLITRK2, CXorf2, KIAA1854, SLITL1
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

SLIK2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.006148 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q810C0, Q8BXL6	Gene names	Slitrk2
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

CYH1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.060459 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.058733 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.057590 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.057621 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	171	Shared Neighborhood Hits	30
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.056285 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.076820 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

DAPP1_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.053238 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.058228 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GAB2_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.050152 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	220	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.071419 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.070046 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.067209 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	119	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA4_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.051868 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	283	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.050748 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	202	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.062501 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

Hits sorted by NC score

OSB11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_MOUSE
NC score	0.997730 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	71	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB10_HUMAN
NC score	0.985121 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL9_HUMAN
NC score	0.946057 (rank : 4)	θ value	1.09934e-114 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL5_MOUSE
NC score	0.839762 (rank : 5)	θ value	8.57503e-51 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	77	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL5_HUMAN
NC score	0.835616 (rank : 6)	θ value	2.94719e-51 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL8_HUMAN
NC score	0.821889 (rank : 7)	θ value	5.73848e-55 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL2_MOUSE
NC score	0.692863 (rank : 8)	θ value	5.60996e-18 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_HUMAN
NC score	0.690645 (rank : 9)	θ value	1.63225e-17 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP1_HUMAN
NC score	0.683649 (rank : 10)	θ value	4.15078e-21 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_HUMAN
NC score	0.674134 (rank : 11)	θ value	9.56915e-18 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBL7_HUMAN
NC score	0.651721 (rank : 12)	θ value	1.52774e-15 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBP2_MOUSE
NC score	0.651702 (rank : 13)	θ value	7.58209e-15 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	150	Shared Neighborhood Hits	35
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL6_HUMAN
NC score	0.633023 (rank : 14)	θ value	9.90251e-15 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
NC score	0.628636 (rank : 15)	θ value	1.42992e-13 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_MOUSE
NC score	0.617565 (rank : 16)	θ value	7.84624e-12 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_HUMAN
NC score	0.608482 (rank : 17)	θ value	5.62301e-10 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL1_MOUSE
NC score	0.495589 (rank : 18)	θ value	1.42661e-21 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	336	Shared Neighborhood Hits	27
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.494081 (rank : 19)	θ value	2.61198e-07 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.488577 (rank : 20)	θ value	1.99992e-07 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

OSBL1_HUMAN
NC score	0.482895 (rank : 21)	θ value	8.36355e-22 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	368	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

C43BP_HUMAN
NC score	0.462027 (rank : 22)	θ value	4.30538e-10 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	87	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.457176 (rank : 23)	θ value	5.62301e-10 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PLEK_MOUSE
NC score	0.223566 (rank : 24)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK2_MOUSE
NC score	0.219522 (rank : 25)	θ value	0.00509761 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.215772 (rank : 26)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	101	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
NC score	0.213932 (rank : 27)	θ value	0.00035302 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	110	Shared Neighborhood Hits	30
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

RHG25_MOUSE
NC score	0.136245 (rank : 28)	θ value	9.29e-05 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	492	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.134994 (rank : 29)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	550	Shared Neighborhood Hits	37
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SWP70_HUMAN
NC score	0.132722 (rank : 30)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	973	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.128242 (rank : 31)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	1097	Shared Neighborhood Hits	37
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA6_HUMAN
NC score	0.115792 (rank : 32)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	556	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CYH4_HUMAN
NC score	0.115521 (rank : 33)	θ value	0.0330416 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

MTMRD_HUMAN
NC score	0.114688 (rank : 34)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

CYH4_MOUSE
NC score	0.113169 (rank : 35)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

PKHA6_MOUSE
NC score	0.108137 (rank : 36)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	591	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GNRP_HUMAN
NC score	0.092706 (rank : 37)	θ value	0.00298849 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	239	Shared Neighborhood Hits	26
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

PKHA2_MOUSE
NC score	0.081004 (rank : 38)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

GNRP_MOUSE
NC score	0.077655 (rank : 39)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	191	Shared Neighborhood Hits	23
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CYH3_MOUSE
NC score	0.076820 (rank : 40)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

MTMR5_HUMAN
NC score	0.072974 (rank : 41)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

PKHA1_HUMAN
NC score	0.071419 (rank : 42)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.070046 (rank : 43)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
NC score	0.067209 (rank : 44)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	119	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA5_HUMAN
NC score	0.062501 (rank : 45)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CYH1_HUMAN
NC score	0.060459 (rank : 46)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.058733 (rank : 47)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

DAPP1_MOUSE
NC score	0.058228 (rank : 48)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CYH2_MOUSE
NC score	0.057621 (rank : 49)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	171	Shared Neighborhood Hits	30
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.057590 (rank : 50)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH3_HUMAN
NC score	0.056285 (rank : 51)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

DAPP1_HUMAN
NC score	0.053238 (rank : 52)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA4_HUMAN
NC score	0.051868 (rank : 53)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	283	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
NC score	0.050748 (rank : 54)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	202	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

GAB2_MOUSE
NC score	0.050152 (rank : 55)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	220	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

CJ084_MOUSE
NC score	0.039387 (rank : 56)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C6C7	Gene names	D19Ertd737e
Domain Architecture	No domain graphic available
Description	Protein C10orf84 homolog.

OS9_HUMAN
NC score	0.033004 (rank : 57)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

K1914_MOUSE
NC score	0.030193 (rank : 58)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1914_HUMAN
NC score	0.029553 (rank : 59)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

CJ084_HUMAN
NC score	0.028725 (rank : 60)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8W3, Q9H5V5	Gene names	C10orf84
Domain Architecture	No domain graphic available
Description	Protein C10orf84.

CAPS1_HUMAN
NC score	0.028087 (rank : 61)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
NC score	0.027468 (rank : 62)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

UBP47_MOUSE
NC score	0.027393 (rank : 63)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

ODPAT_HUMAN
NC score	0.023075 (rank : 64)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P29803	Gene names	PDHA2
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II).

APS_MOUSE
NC score	0.018729 (rank : 65)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_HUMAN
NC score	0.017452 (rank : 66)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CENG3_HUMAN
NC score	0.016637 (rank : 67)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	455	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
NC score	0.014971 (rank : 68)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

MPP8_HUMAN
NC score	0.014200 (rank : 69)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	948	Shared Neighborhood Hits	7
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SPTB2_HUMAN
NC score	0.012401 (rank : 70)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	748	Shared Neighborhood Hits	20
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SLIK2_HUMAN
NC score	0.006173 (rank : 71)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H156, Q5JXB1, Q8NBC7, Q96JH3	Gene names	SLITRK2, CXorf2, KIAA1854, SLITL1
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

SLIK2_MOUSE
NC score	0.006148 (rank : 72)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q810C0, Q8BXL6	Gene names	Slitrk2
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

CROCC_HUMAN
NC score	0.004361 (rank : 73)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	1409	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

NKTR_HUMAN
NC score	0.002630 (rank : 74)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	658	Shared Neighborhood Hits	3
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

KLHL4_HUMAN
NC score	0.000587 (rank : 75)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.