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Network neighborhood for query Sequence : OSBL5_MOUSE

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OSBL5_MOUSE
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBL5_HUMAN
θ value	0 (rank : 1)	NC score	0.988950 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL8_HUMAN
θ value	0 (rank : 3)	NC score	0.951066 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB11_MOUSE
θ value	1.72781e-51 (rank : 4)	NC score	0.839830 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB10_HUMAN
θ value	3.84914e-51 (rank : 5)	NC score	0.864301 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_HUMAN
θ value	8.57503e-51 (rank : 6)	NC score	0.839762 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
θ value	3.37202e-47 (rank : 7)	NC score	0.835574 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	138	Shared Neighborhood Hits	24
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL1_MOUSE
θ value	2.42779e-29 (rank : 8)	NC score	0.533386 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	336	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
θ value	5.40856e-29 (rank : 9)	NC score	0.521187 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	368	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL2_HUMAN
θ value	6.61148e-27 (rank : 10)	NC score	0.769015 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
θ value	2.12685e-25 (rank : 11)	NC score	0.766355 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL6_HUMAN
θ value	1.37858e-24 (rank : 12)	NC score	0.704826 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	1.99067e-23 (rank : 13)	NC score	0.696449 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL7_HUMAN
θ value	2.06002e-20 (rank : 14)	NC score	0.711436 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL3_MOUSE
θ value	6.62687e-19 (rank : 15)	NC score	0.695458 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP2_MOUSE
θ value	2.5182e-18 (rank : 16)	NC score	0.678707 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	150	Shared Neighborhood Hits	27
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBP2_HUMAN
θ value	3.28887e-18 (rank : 17)	NC score	0.687657 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	154	Shared Neighborhood Hits	30
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBL3_HUMAN
θ value	1.24977e-17 (rank : 18)	NC score	0.681702 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP1_HUMAN
θ value	1.63225e-17 (rank : 19)	NC score	0.684812 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	31
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CYH4_MOUSE
θ value	0.0193708 (rank : 20)	NC score	0.124106 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
θ value	0.0736092 (rank : 21)	NC score	0.121167 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

SWP70_MOUSE
θ value	0.0961366 (rank : 22)	NC score	0.092770 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	1097	Shared Neighborhood Hits	34
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.095916 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	973	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CP250_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.010095 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	1805	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CYH3_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.096452 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	148	Shared Neighborhood Hits	22
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH1_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.084222 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.083961 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	184	Shared Neighborhood Hits	21
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

MYO15_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.007683 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	671	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

AN32E_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.022769 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

NCA11_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.006162 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	661	Shared Neighborhood Hits	5
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

MAP2_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.018364 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	348	Shared Neighborhood Hits	9
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

PRPF3_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.047143 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.046817 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

URFB1_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.028768 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

ZN142_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.000171 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	1007	Shared Neighborhood Hits	8
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

CYH2_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.078654 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.078331 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	171	Shared Neighborhood Hits	20
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.079685 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	137	Shared Neighborhood Hits	20
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

KI21A_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.005904 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	1543	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

NOB1_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.020714 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULX3, Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0	Gene names	NOB1, ART4, NOB1P, PSMD8BP1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1 (Protein ART-4) (Phosphorylation regulatory protein HP-10).

PELP1_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.049519 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	596	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ARS2_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.030305 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

AT133_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.008698 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7F0, Q8NC11, Q96KS1	Gene names	ATP13A3, AFURS1
Domain Architecture
Description	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1).

CCDC4_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.023444 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

ARHG1_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.013168 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

BRD4_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.009729 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	851	Shared Neighborhood Hits	16
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DAXX_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.034044 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

K0423_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.012641 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

PAG1_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.016733 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U1F9, Q8BFS1, Q9EQF3	Gene names	Pag1, Cbp, Pag
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

TARA_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.032998 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	1133	Shared Neighborhood Hits	28
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BRD4_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.008566 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	845	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PELP1_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.036905 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	709	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RB6I2_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.005597 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	1584	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.006175 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	1433	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SET1A_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.014868 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	690	Shared Neighborhood Hits	12
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SMUF1_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.009155 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.009071 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

ZN326_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.014661 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

APOA1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.011753 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	7
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

FAM9A_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.012995 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

LEO1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.018590 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.020472 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	946	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SREC2_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.001020 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TEX14_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.013519 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	1103	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

AMPB_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.005152 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4A4, Q9BVM9, Q9H1D4, Q9NPT7	Gene names	RNPEP, APB
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase).

ANR47_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.021234 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CRCM_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.006970 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	520	Shared Neighborhood Hits	6
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

DNM3A_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.005528 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

GLDN_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.013542 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

HORN_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.005857 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

PITM3_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.005321 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

RAPH1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.005074 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	593	Shared Neighborhood Hits	7
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RFC1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.008175 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

SOX4_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.002817 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SSH1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.003989 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

TNIK_HUMAN
θ value	8.99809 (rank : 76)	NC score	-0.002244 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	1570	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

ZC3H6_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.006294 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	239	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

C43BP_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.238396 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.233816 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

MTMRD_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.052138 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA3_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.268618 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.275033 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.050812 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.074643 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.077108 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.071109 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.075883 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RHG25_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.055410 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	550	Shared Neighborhood Hits	28
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.057090 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

Hits sorted by NC score

OSBL5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL5_HUMAN
NC score	0.988950 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL8_HUMAN
NC score	0.951066 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB10_HUMAN
NC score	0.864301 (rank : 4)	θ value	3.84914e-51 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_MOUSE
NC score	0.839830 (rank : 5)	θ value	1.72781e-51 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
NC score	0.839762 (rank : 6)	θ value	8.57503e-51 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
NC score	0.835574 (rank : 7)	θ value	3.37202e-47 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	138	Shared Neighborhood Hits	24
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL2_HUMAN
NC score	0.769015 (rank : 8)	θ value	6.61148e-27 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
NC score	0.766355 (rank : 9)	θ value	2.12685e-25 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL7_HUMAN
NC score	0.711436 (rank : 10)	θ value	2.06002e-20 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL6_HUMAN
NC score	0.704826 (rank : 11)	θ value	1.37858e-24 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
NC score	0.696449 (rank : 12)	θ value	1.99067e-23 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
NC score	0.695458 (rank : 13)	θ value	6.62687e-19 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP2_HUMAN
NC score	0.687657 (rank : 14)	θ value	3.28887e-18 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	154	Shared Neighborhood Hits	30
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP1_HUMAN
NC score	0.684812 (rank : 15)	θ value	1.63225e-17 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	31
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL3_HUMAN
NC score	0.681702 (rank : 16)	θ value	1.24977e-17 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP2_MOUSE
NC score	0.678707 (rank : 17)	θ value	2.5182e-18 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	150	Shared Neighborhood Hits	27
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL1_MOUSE
NC score	0.533386 (rank : 18)	θ value	2.42779e-29 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	336	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
NC score	0.521187 (rank : 19)	θ value	5.40856e-29 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	368	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.275033 (rank : 20)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.268618 (rank : 21)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.238396 (rank : 22)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.233816 (rank : 23)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CYH4_MOUSE
NC score	0.124106 (rank : 24)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.121167 (rank : 25)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH3_MOUSE
NC score	0.096452 (rank : 26)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	148	Shared Neighborhood Hits	22
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SWP70_HUMAN
NC score	0.095916 (rank : 27)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	973	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.092770 (rank : 28)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	1097	Shared Neighborhood Hits	34
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CYH1_MOUSE
NC score	0.084222 (rank : 29)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
NC score	0.083961 (rank : 30)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	184	Shared Neighborhood Hits	21
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_HUMAN
NC score	0.079685 (rank : 31)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	137	Shared Neighborhood Hits	20
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_HUMAN
NC score	0.078654 (rank : 32)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.078331 (rank : 33)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	171	Shared Neighborhood Hits	20
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

PLEK2_MOUSE
NC score	0.077108 (rank : 34)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_MOUSE
NC score	0.075883 (rank : 35)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK2_HUMAN
NC score	0.074643 (rank : 36)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
NC score	0.071109 (rank : 37)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

RHG25_MOUSE
NC score	0.057090 (rank : 38)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.055410 (rank : 39)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	550	Shared Neighborhood Hits	28
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MTMRD_HUMAN
NC score	0.052138 (rank : 40)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA6_HUMAN
NC score	0.050812 (rank : 41)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PELP1_HUMAN
NC score	0.049519 (rank : 42)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	596	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PRPF3_HUMAN
NC score	0.047143 (rank : 43)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
NC score	0.046817 (rank : 44)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

PELP1_MOUSE
NC score	0.036905 (rank : 45)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	709	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

DAXX_HUMAN
NC score	0.034044 (rank : 46)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

TARA_MOUSE
NC score	0.032998 (rank : 47)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	1133	Shared Neighborhood Hits	28
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ARS2_HUMAN
NC score	0.030305 (rank : 48)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

URFB1_HUMAN
NC score	0.028768 (rank : 49)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

CCDC4_HUMAN
NC score	0.023444 (rank : 50)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

AN32E_HUMAN
NC score	0.022769 (rank : 51)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

ANR47_HUMAN
NC score	0.021234 (rank : 52)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NOB1_HUMAN
NC score	0.020714 (rank : 53)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULX3, Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0	Gene names	NOB1, ART4, NOB1P, PSMD8BP1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1 (Protein ART-4) (Phosphorylation regulatory protein HP-10).

LEO1_MOUSE
NC score	0.020472 (rank : 54)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	946	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.018590 (rank : 55)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAP2_HUMAN
NC score	0.018364 (rank : 56)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	348	Shared Neighborhood Hits	9
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

PAG1_MOUSE
NC score	0.016733 (rank : 57)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U1F9, Q8BFS1, Q9EQF3	Gene names	Pag1, Cbp, Pag
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

SET1A_HUMAN
NC score	0.014868 (rank : 58)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	690	Shared Neighborhood Hits	12
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ZN326_HUMAN
NC score	0.014661 (rank : 59)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

GLDN_MOUSE
NC score	0.013542 (rank : 60)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

TEX14_HUMAN
NC score	0.013519 (rank : 61)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	1103	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ARHG1_MOUSE
NC score	0.013168 (rank : 62)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

FAM9A_HUMAN
NC score	0.012995 (rank : 63)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

K0423_HUMAN
NC score	0.012641 (rank : 64)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

APOA1_HUMAN
NC score	0.011753 (rank : 65)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	7
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

CP250_HUMAN
NC score	0.010095 (rank : 66)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	1805	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

BRD4_HUMAN
NC score	0.009729 (rank : 67)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	851	Shared Neighborhood Hits	16
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

SMUF1_HUMAN
NC score	0.009155 (rank : 68)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.009071 (rank : 69)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

AT133_HUMAN
NC score	0.008698 (rank : 70)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7F0, Q8NC11, Q96KS1	Gene names	ATP13A3, AFURS1
Domain Architecture
Description	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1).

BRD4_MOUSE
NC score	0.008566 (rank : 71)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	845	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RFC1_HUMAN
NC score	0.008175 (rank : 72)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

MYO15_HUMAN
NC score	0.007683 (rank : 73)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	671	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CRCM_HUMAN
NC score	0.006970 (rank : 74)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	520	Shared Neighborhood Hits	6
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

ZC3H6_MOUSE
NC score	0.006294 (rank : 75)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	239	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

RB6I2_MOUSE
NC score	0.006175 (rank : 76)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	1433	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

NCA11_MOUSE
NC score	0.006162 (rank : 77)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	661	Shared Neighborhood Hits	5
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

KI21A_HUMAN
NC score	0.005904 (rank : 78)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	1543	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

HORN_HUMAN
NC score	0.005857 (rank : 79)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

RB6I2_HUMAN
NC score	0.005597 (rank : 80)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	1584	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

DNM3A_HUMAN
NC score	0.005528 (rank : 81)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

PITM3_MOUSE
NC score	0.005321 (rank : 82)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

AMPB_HUMAN
NC score	0.005152 (rank : 83)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4A4, Q9BVM9, Q9H1D4, Q9NPT7	Gene names	RNPEP, APB
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase).

RAPH1_HUMAN
NC score	0.005074 (rank : 84)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	593	Shared Neighborhood Hits	7
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SSH1_HUMAN
NC score	0.003989 (rank : 85)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SOX4_HUMAN
NC score	0.002817 (rank : 86)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SREC2_MOUSE
NC score	0.001020 (rank : 87)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ZN142_HUMAN
NC score	0.000171 (rank : 88)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	1007	Shared Neighborhood Hits	8
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

TNIK_HUMAN
NC score	-0.002244 (rank : 89)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	1570	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).