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Network neighborhood for query Sequence : OSBL9_HUMAN

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OSBL9_HUMAN
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBL9_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	138	Target Neighborhood Hits	138	Shared Neighborhood Hits	138
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB11_MOUSE
θ value	1.17455e-116 (rank : 2)	NC score	0.947440 (rank : 3)
Query Neighborhood Hits	138	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
θ value	1.09934e-114 (rank : 3)	NC score	0.946057 (rank : 4)
Query Neighborhood Hits	138	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB10_HUMAN
θ value	6.6695e-112 (rank : 4)	NC score	0.949243 (rank : 2)
Query Neighborhood Hits	138	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL8_HUMAN
θ value	2.84138e-62 (rank : 5)	NC score	0.821218 (rank : 7)
Query Neighborhood Hits	138	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL5_HUMAN
θ value	7.25919e-50 (rank : 6)	NC score	0.832354 (rank : 6)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	3.37202e-47 (rank : 7)	NC score	0.835574 (rank : 5)
Query Neighborhood Hits	138	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL1_MOUSE
θ value	1.92365e-26 (rank : 8)	NC score	0.517436 (rank : 22)
Query Neighborhood Hits	138	Target Neighborhood Hits	336	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
θ value	4.43474e-23 (rank : 9)	NC score	0.503386 (rank : 23)
Query Neighborhood Hits	138	Target Neighborhood Hits	368	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL2_MOUSE
θ value	2.87452e-22 (rank : 10)	NC score	0.711926 (rank : 9)
Query Neighborhood Hits	138	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_HUMAN
θ value	2.43343e-21 (rank : 11)	NC score	0.710458 (rank : 10)
Query Neighborhood Hits	138	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP1_HUMAN
θ value	3.28887e-18 (rank : 12)	NC score	0.716550 (rank : 8)
Query Neighborhood Hits	138	Target Neighborhood Hits	180	Shared Neighborhood Hits	70
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL6_HUMAN
θ value	2.7842e-17 (rank : 13)	NC score	0.664512 (rank : 14)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL7_HUMAN
θ value	1.058e-16 (rank : 14)	NC score	0.678974 (rank : 12)
Query Neighborhood Hits	138	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

PKHA3_MOUSE
θ value	1.058e-16 (rank : 15)	NC score	0.572430 (rank : 18)
Query Neighborhood Hits	138	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

OSBL3_MOUSE
θ value	1.38178e-16 (rank : 16)	NC score	0.661858 (rank : 15)
Query Neighborhood Hits	138	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKHA3_HUMAN
θ value	1.38178e-16 (rank : 17)	NC score	0.569052 (rank : 19)
Query Neighborhood Hits	138	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
θ value	8.95645e-16 (rank : 18)	NC score	0.525976 (rank : 20)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBL6_MOUSE
θ value	7.58209e-15 (rank : 19)	NC score	0.650943 (rank : 16)
Query Neighborhood Hits	138	Target Neighborhood Hits	105	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

C43BP_MOUSE
θ value	1.29331e-14 (rank : 20)	NC score	0.521419 (rank : 21)
Query Neighborhood Hits	138	Target Neighborhood Hits	91	Shared Neighborhood Hits	56
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBL3_HUMAN
θ value	1.29331e-14 (rank : 21)	NC score	0.645827 (rank : 17)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP2_HUMAN
θ value	2.0648e-12 (rank : 22)	NC score	0.696481 (rank : 11)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	6.21693e-09 (rank : 23)	NC score	0.673269 (rank : 13)
Query Neighborhood Hits	138	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

SWP70_MOUSE
θ value	7.59969e-07 (rank : 24)	NC score	0.177204 (rank : 29)
Query Neighborhood Hits	138	Target Neighborhood Hits	1097	Shared Neighborhood Hits	82
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_HUMAN
θ value	4.92598e-06 (rank : 25)	NC score	0.181875 (rank : 28)
Query Neighborhood Hits	138	Target Neighborhood Hits	973	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MTMRD_HUMAN
θ value	0.000270298 (rank : 26)	NC score	0.161335 (rank : 30)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PLEK_MOUSE
θ value	0.000602161 (rank : 27)	NC score	0.241925 (rank : 24)
Query Neighborhood Hits	138	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK_HUMAN
θ value	0.00102713 (rank : 28)	NC score	0.235173 (rank : 27)
Query Neighborhood Hits	138	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK2_MOUSE
θ value	0.00298849 (rank : 29)	NC score	0.240429 (rank : 25)
Query Neighborhood Hits	138	Target Neighborhood Hits	96	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
θ value	0.00665767 (rank : 30)	NC score	0.236187 (rank : 26)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

MTMR5_HUMAN
θ value	0.00869519 (rank : 31)	NC score	0.117949 (rank : 41)
Query Neighborhood Hits	138	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

FGD1_HUMAN
θ value	0.0193708 (rank : 32)	NC score	0.079655 (rank : 56)
Query Neighborhood Hits	138	Target Neighborhood Hits	367	Shared Neighborhood Hits	29
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	0.0193708 (rank : 33)	NC score	0.079324 (rank : 57)
Query Neighborhood Hits	138	Target Neighborhood Hits	387	Shared Neighborhood Hits	29
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD6_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.102283 (rank : 43)
Query Neighborhood Hits	138	Target Neighborhood Hits	237	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

RBBP6_MOUSE
θ value	0.0252991 (rank : 35)	NC score	0.040792 (rank : 98)
Query Neighborhood Hits	138	Target Neighborhood Hits	1014	Shared Neighborhood Hits	13
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

CEND1_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.087137 (rank : 52)
Query Neighborhood Hits	138	Target Neighborhood Hits	284	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CYH4_MOUSE
θ value	0.0330416 (rank : 37)	NC score	0.134991 (rank : 35)
Query Neighborhood Hits	138	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

FGD4_HUMAN
θ value	0.0431538 (rank : 38)	NC score	0.077293 (rank : 61)
Query Neighborhood Hits	138	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

DAPP1_MOUSE
θ value	0.0563607 (rank : 39)	NC score	0.102173 (rank : 44)
Query Neighborhood Hits	138	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RBBP6_HUMAN
θ value	0.0563607 (rank : 40)	NC score	0.038231 (rank : 99)
Query Neighborhood Hits	138	Target Neighborhood Hits	1135	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RHG25_MOUSE
θ value	0.0563607 (rank : 41)	NC score	0.125425 (rank : 38)
Query Neighborhood Hits	138	Target Neighborhood Hits	492	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

DDEF1_MOUSE
θ value	0.0736092 (rank : 42)	NC score	0.092942 (rank : 49)
Query Neighborhood Hits	138	Target Neighborhood Hits	592	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ANK2_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.030602 (rank : 107)
Query Neighborhood Hits	138	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CYH4_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.132484 (rank : 37)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

FGD5_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.087211 (rank : 51)
Query Neighborhood Hits	138	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

PKHA6_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.154141 (rank : 31)
Query Neighborhood Hits	138	Target Neighborhood Hits	556	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TACC3_MOUSE
θ value	0.163984 (rank : 47)	NC score	0.030790 (rank : 106)
Query Neighborhood Hits	138	Target Neighborhood Hits	607	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

DAPP1_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.096222 (rank : 47)
Query Neighborhood Hits	138	Target Neighborhood Hits	227	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

FARP2_MOUSE
θ value	0.21417 (rank : 49)	NC score	0.066960 (rank : 75)
Query Neighborhood Hits	138	Target Neighborhood Hits	209	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD5_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.087267 (rank : 50)
Query Neighborhood Hits	138	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

PKHA1_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.136276 (rank : 33)
Query Neighborhood Hits	138	Target Neighborhood Hits	127	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	0.21417 (rank : 52)	NC score	0.136054 (rank : 34)
Query Neighborhood Hits	138	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA6_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.147873 (rank : 32)
Query Neighborhood Hits	138	Target Neighborhood Hits	591	Shared Neighborhood Hits	65
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

BMX_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.010185 (rank : 134)
Query Neighborhood Hits	138	Target Neighborhood Hits	942	Shared Neighborhood Hits	28
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CENG3_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.053764 (rank : 89)
Query Neighborhood Hits	138	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

FARP2_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.065335 (rank : 76)
Query Neighborhood Hits	138	Target Neighborhood Hits	240	Shared Neighborhood Hits	36
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD6_MOUSE
θ value	0.365318 (rank : 57)	NC score	0.101709 (rank : 45)
Query Neighborhood Hits	138	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

MYO10_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.056388 (rank : 88)
Query Neighborhood Hits	138	Target Neighborhood Hits	920	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

BMX_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.009093 (rank : 138)
Query Neighborhood Hits	138	Target Neighborhood Hits	912	Shared Neighborhood Hits	28
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

PAX3_HUMAN
θ value	0.47712 (rank : 60)	NC score	0.008128 (rank : 142)
Query Neighborhood Hits	138	Target Neighborhood Hits	513	Shared Neighborhood Hits	9
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

CEND1_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.070829 (rank : 67)
Query Neighborhood Hits	138	Target Neighborhood Hits	260	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

DDFL1_HUMAN
θ value	0.62314 (rank : 62)	NC score	0.072813 (rank : 65)
Query Neighborhood Hits	138	Target Neighborhood Hits	353	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CCD91_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.029931 (rank : 108)
Query Neighborhood Hits	138	Target Neighborhood Hits	699	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

FGD4_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.074622 (rank : 63)
Query Neighborhood Hits	138	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

PHLB1_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.058653 (rank : 84)
Query Neighborhood Hits	138	Target Neighborhood Hits	1038	Shared Neighborhood Hits	56
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.069019 (rank : 73)
Query Neighborhood Hits	138	Target Neighborhood Hits	678	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.057372 (rank : 86)
Query Neighborhood Hits	138	Target Neighborhood Hits	1016	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA5_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.101496 (rank : 46)
Query Neighborhood Hits	138	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RHG25_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.123161 (rank : 39)
Query Neighborhood Hits	138	Target Neighborhood Hits	550	Shared Neighborhood Hits	65
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CENG2_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.049337 (rank : 96)
Query Neighborhood Hits	138	Target Neighborhood Hits	471	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG3_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.051725 (rank : 92)
Query Neighborhood Hits	138	Target Neighborhood Hits	467	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

MORC2_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.016743 (rank : 118)
Query Neighborhood Hits	138	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

PHLB2_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.056588 (rank : 87)
Query Neighborhood Hits	138	Target Neighborhood Hits	964	Shared Neighborhood Hits	51
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SOS1_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.037801 (rank : 100)
Query Neighborhood Hits	138	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

CK060_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.036660 (rank : 103)
Query Neighborhood Hits	138	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DB07, Q91Z06, Q9JHT1	Gene names
Domain Architecture	No domain graphic available
Description	UPF0360 protein C11orf60 homolog.

PCSK7_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.017785 (rank : 111)
Query Neighborhood Hits	138	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.017747 (rank : 112)
Query Neighborhood Hits	138	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

CCD91_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.027667 (rank : 109)
Query Neighborhood Hits	138	Target Neighborhood Hits	868	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CENG2_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.049462 (rank : 95)
Query Neighborhood Hits	138	Target Neighborhood Hits	463	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CYH3_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.104894 (rank : 42)
Query Neighborhood Hits	138	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CEND2_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.076182 (rank : 62)
Query Neighborhood Hits	138	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CENG1_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.050763 (rank : 94)
Query Neighborhood Hits	138	Target Neighborhood Hits	544	Shared Neighborhood Hits	25
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.051409 (rank : 93)
Query Neighborhood Hits	138	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CK060_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.033960 (rank : 104)
Query Neighborhood Hits	138	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC8	Gene names	C11orf60, C11orf2
Domain Architecture	No domain graphic available
Description	UPF0360 protein C11orf60.

FRAP_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.016099 (rank : 120)
Query Neighborhood Hits	138	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

ZN409_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.005738 (rank : 149)
Query Neighborhood Hits	138	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

AKT2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.007242 (rank : 145)
Query Neighborhood Hits	138	Target Neighborhood Hits	878	Shared Neighborhood Hits	31
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT2_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.007111 (rank : 147)
Query Neighborhood Hits	138	Target Neighborhood Hits	875	Shared Neighborhood Hits	31
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AL2S8_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.017650 (rank : 113)
Query Neighborhood Hits	138	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

ANGP2_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.009008 (rank : 139)
Query Neighborhood Hits	138	Target Neighborhood Hits	400	Shared Neighborhood Hits	17
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

DDFL1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.069723 (rank : 70)
Query Neighborhood Hits	138	Target Neighborhood Hits	324	Shared Neighborhood Hits	35
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

LR37A_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.008807 (rank : 140)
Query Neighborhood Hits	138	Target Neighborhood Hits	720	Shared Neighborhood Hits	11
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MYPN_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.010298 (rank : 133)
Query Neighborhood Hits	138	Target Neighborhood Hits	421	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

SOS2_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.037030 (rank : 102)
Query Neighborhood Hits	138	Target Neighborhood Hits	193	Shared Neighborhood Hits	21
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

CMTA1_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.014060 (rank : 124)
Query Neighborhood Hits	138	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CT172_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.017444 (rank : 114)
Query Neighborhood Hits	138	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYC5, Q9CYF2, Q9DA26	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172 homolog.

GNRP_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.094587 (rank : 48)
Query Neighborhood Hits	138	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

PKHA2_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.132871 (rank : 36)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PREX1_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.044729 (rank : 97)
Query Neighborhood Hits	138	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

CASP_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.016046 (rank : 121)
Query Neighborhood Hits	138	Target Neighborhood Hits	1152	Shared Neighborhood Hits	31
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CP135_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.010942 (rank : 131)
Query Neighborhood Hits	138	Target Neighborhood Hits	1278	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CUTL1_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.016915 (rank : 116)
Query Neighborhood Hits	138	Target Neighborhood Hits	1620	Shared Neighborhood Hits	37
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DGKH_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.037176 (rank : 101)
Query Neighborhood Hits	138	Target Neighborhood Hits	255	Shared Neighborhood Hits	37
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ENH3_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.007847 (rank : 143)
Query Neighborhood Hits	138	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

GNRP_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.084763 (rank : 53)
Query Neighborhood Hits	138	Target Neighborhood Hits	191	Shared Neighborhood Hits	46
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOGB1_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.015082 (rank : 123)
Query Neighborhood Hits	138	Target Neighborhood Hits	2297	Shared Neighborhood Hits	51
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

K1210_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.016444 (rank : 119)
Query Neighborhood Hits	138	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

LAP2_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.001229 (rank : 153)
Query Neighborhood Hits	138	Target Neighborhood Hits	499	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MYH13_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.010040 (rank : 136)
Query Neighborhood Hits	138	Target Neighborhood Hits	1504	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PC11X_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.000620 (rank : 154)
Query Neighborhood Hits	138	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PPRB_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.013578 (rank : 127)
Query Neighborhood Hits	138	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SDS3_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.018220 (rank : 110)
Query Neighborhood Hits	138	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

UBAP1_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.013666 (rank : 126)
Query Neighborhood Hits	138	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

WNK2_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.001421 (rank : 152)
Query Neighborhood Hits	138	Target Neighborhood Hits	1407	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CASP_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.015909 (rank : 122)
Query Neighborhood Hits	138	Target Neighborhood Hits	1131	Shared Neighborhood Hits	31
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD37_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.016959 (rank : 115)
Query Neighborhood Hits	138	Target Neighborhood Hits	248	Shared Neighborhood Hits	17
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CE152_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.012907 (rank : 128)
Query Neighborhood Hits	138	Target Neighborhood Hits	976	Shared Neighborhood Hits	27
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CUTL1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.016868 (rank : 117)
Query Neighborhood Hits	138	Target Neighborhood Hits	1574	Shared Neighborhood Hits	38
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FRAP_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.013781 (rank : 125)
Query Neighborhood Hits	138	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

MY18A_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.010166 (rank : 135)
Query Neighborhood Hits	138	Target Neighborhood Hits	1989	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PKHA2_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.121539 (rank : 40)
Query Neighborhood Hits	138	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

ATN1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.009466 (rank : 137)
Query Neighborhood Hits	138	Target Neighborhood Hits	676	Shared Neighborhood Hits	16
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CF060_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.010859 (rank : 132)
Query Neighborhood Hits	138	Target Neighborhood Hits	1270	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CP135_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.011706 (rank : 130)
Query Neighborhood Hits	138	Target Neighborhood Hits	1290	Shared Neighborhood Hits	33
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DDEF2_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.069028 (rank : 72)
Query Neighborhood Hits	138	Target Neighborhood Hits	599	Shared Neighborhood Hits	43
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.068528 (rank : 74)
Query Neighborhood Hits	138	Target Neighborhood Hits	625	Shared Neighborhood Hits	42
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FGD2_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.062187 (rank : 79)
Query Neighborhood Hits	138	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

GAB2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.064829 (rank : 77)
Query Neighborhood Hits	138	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

K0319_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.008198 (rank : 141)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

MAST1_HUMAN
θ value	8.99809 (rank : 130)	NC score	-0.000824 (rank : 155)
Query Neighborhood Hits	138	Target Neighborhood Hits	1146	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	8.99809 (rank : 131)	NC score	-0.001029 (rank : 156)
Query Neighborhood Hits	138	Target Neighborhood Hits	1123	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NF2L1_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.007139 (rank : 146)
Query Neighborhood Hits	138	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

NIPBL_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.005935 (rank : 148)
Query Neighborhood Hits	138	Target Neighborhood Hits	1311	Shared Neighborhood Hits	19
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PACN2_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.007401 (rank : 144)
Query Neighborhood Hits	138	Target Neighborhood Hits	382	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PAX3_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.004493 (rank : 151)
Query Neighborhood Hits	138	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

RBCC1_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.012002 (rank : 129)
Query Neighborhood Hits	138	Target Neighborhood Hits	1023	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SOS1_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.032128 (rank : 105)
Query Neighborhood Hits	138	Target Neighborhood Hits	281	Shared Neighborhood Hits	19
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

UBP7_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.004602 (rank : 150)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

CENA1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.052727 (rank : 90)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.059594 (rank : 82)
Query Neighborhood Hits	138	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.069518 (rank : 71)
Query Neighborhood Hits	138	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.061449 (rank : 80)
Query Neighborhood Hits	138	Target Neighborhood Hits	425	Shared Neighborhood Hits	50
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.069974 (rank : 68)
Query Neighborhood Hits	138	Target Neighborhood Hits	395	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CYH1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.084390 (rank : 54)
Query Neighborhood Hits	138	Target Neighborhood Hits	184	Shared Neighborhood Hits	62
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.082039 (rank : 55)
Query Neighborhood Hits	138	Target Neighborhood Hits	176	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.079253 (rank : 60)
Query Neighborhood Hits	138	Target Neighborhood Hits	175	Shared Neighborhood Hits	57
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.079255 (rank : 59)
Query Neighborhood Hits	138	Target Neighborhood Hits	171	Shared Neighborhood Hits	57
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.079289 (rank : 58)
Query Neighborhood Hits	138	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

FARP1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.062745 (rank : 78)
Query Neighborhood Hits	138	Target Neighborhood Hits	241	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FGD2_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.059186 (rank : 83)
Query Neighborhood Hits	138	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD3_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.057975 (rank : 85)
Query Neighborhood Hits	138	Target Neighborhood Hits	249	Shared Neighborhood Hits	23
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.061438 (rank : 81)
Query Neighborhood Hits	138	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

GAB1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.052033 (rank : 91)
Query Neighborhood Hits	138	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.073905 (rank : 64)
Query Neighborhood Hits	138	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA4_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.069898 (rank : 69)
Query Neighborhood Hits	138	Target Neighborhood Hits	283	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.071700 (rank : 66)
Query Neighborhood Hits	138	Target Neighborhood Hits	202	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

Hits sorted by NC score

OSBL9_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	138	Target Neighborhood Hits	138	Shared Neighborhood Hits	138
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB10_HUMAN
NC score	0.949243 (rank : 2)	θ value	6.6695e-112 (rank : 4)
Query Neighborhood Hits	138	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_MOUSE
NC score	0.947440 (rank : 3)	θ value	1.17455e-116 (rank : 2)
Query Neighborhood Hits	138	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
NC score	0.946057 (rank : 4)	θ value	1.09934e-114 (rank : 3)
Query Neighborhood Hits	138	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL5_MOUSE
NC score	0.835574 (rank : 5)	θ value	3.37202e-47 (rank : 7)
Query Neighborhood Hits	138	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL5_HUMAN
NC score	0.832354 (rank : 6)	θ value	7.25919e-50 (rank : 6)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL8_HUMAN
NC score	0.821218 (rank : 7)	θ value	2.84138e-62 (rank : 5)
Query Neighborhood Hits	138	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBP1_HUMAN
NC score	0.716550 (rank : 8)	θ value	3.28887e-18 (rank : 12)
Query Neighborhood Hits	138	Target Neighborhood Hits	180	Shared Neighborhood Hits	70
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL2_MOUSE
NC score	0.711926 (rank : 9)	θ value	2.87452e-22 (rank : 10)
Query Neighborhood Hits	138	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_HUMAN
NC score	0.710458 (rank : 10)	θ value	2.43343e-21 (rank : 11)
Query Neighborhood Hits	138	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP2_HUMAN
NC score	0.696481 (rank : 11)	θ value	2.0648e-12 (rank : 22)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBL7_HUMAN
NC score	0.678974 (rank : 12)	θ value	1.058e-16 (rank : 14)
Query Neighborhood Hits	138	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBP2_MOUSE
NC score	0.673269 (rank : 13)	θ value	6.21693e-09 (rank : 23)
Query Neighborhood Hits	138	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL6_HUMAN
NC score	0.664512 (rank : 14)	θ value	2.7842e-17 (rank : 13)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
NC score	0.661858 (rank : 15)	θ value	1.38178e-16 (rank : 16)
Query Neighborhood Hits	138	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_MOUSE
NC score	0.650943 (rank : 16)	θ value	7.58209e-15 (rank : 19)
Query Neighborhood Hits	138	Target Neighborhood Hits	105	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_HUMAN
NC score	0.645827 (rank : 17)	θ value	1.29331e-14 (rank : 21)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKHA3_MOUSE
NC score	0.572430 (rank : 18)	θ value	1.058e-16 (rank : 15)
Query Neighborhood Hits	138	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.569052 (rank : 19)	θ value	1.38178e-16 (rank : 17)
Query Neighborhood Hits	138	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.525976 (rank : 20)	θ value	8.95645e-16 (rank : 18)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.521419 (rank : 21)	θ value	1.29331e-14 (rank : 20)
Query Neighborhood Hits	138	Target Neighborhood Hits	91	Shared Neighborhood Hits	56
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBL1_MOUSE
NC score	0.517436 (rank : 22)	θ value	1.92365e-26 (rank : 8)
Query Neighborhood Hits	138	Target Neighborhood Hits	336	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
NC score	0.503386 (rank : 23)	θ value	4.43474e-23 (rank : 9)
Query Neighborhood Hits	138	Target Neighborhood Hits	368	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PLEK_MOUSE
NC score	0.241925 (rank : 24)	θ value	0.000602161 (rank : 27)
Query Neighborhood Hits	138	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK2_MOUSE
NC score	0.240429 (rank : 25)	θ value	0.00298849 (rank : 29)
Query Neighborhood Hits	138	Target Neighborhood Hits	96	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.236187 (rank : 26)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
NC score	0.235173 (rank : 27)	θ value	0.00102713 (rank : 28)
Query Neighborhood Hits	138	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

SWP70_HUMAN
NC score	0.181875 (rank : 28)	θ value	4.92598e-06 (rank : 25)
Query Neighborhood Hits	138	Target Neighborhood Hits	973	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.177204 (rank : 29)	θ value	7.59969e-07 (rank : 24)
Query Neighborhood Hits	138	Target Neighborhood Hits	1097	Shared Neighborhood Hits	82
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MTMRD_HUMAN
NC score	0.161335 (rank : 30)	θ value	0.000270298 (rank : 26)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA6_HUMAN
NC score	0.154141 (rank : 31)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	138	Target Neighborhood Hits	556	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.147873 (rank : 32)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	138	Target Neighborhood Hits	591	Shared Neighborhood Hits	65
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_HUMAN
NC score	0.136276 (rank : 33)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	138	Target Neighborhood Hits	127	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.136054 (rank : 34)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	138	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CYH4_MOUSE
NC score	0.134991 (rank : 35)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	138	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

PKHA2_MOUSE
NC score	0.132871 (rank : 36)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

CYH4_HUMAN
NC score	0.132484 (rank : 37)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

RHG25_MOUSE
NC score	0.125425 (rank : 38)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	138	Target Neighborhood Hits	492	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.123161 (rank : 39)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	138	Target Neighborhood Hits	550	Shared Neighborhood Hits	65
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA2_HUMAN
NC score	0.121539 (rank : 40)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	138	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

MTMR5_HUMAN
NC score	0.117949 (rank : 41)	θ value	0.00869519 (rank : 31)
Query Neighborhood Hits	138	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

CYH3_MOUSE
NC score	0.104894 (rank : 42)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	138	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

FGD6_HUMAN
NC score	0.102283 (rank : 43)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	138	Target Neighborhood Hits	237	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

DAPP1_MOUSE
NC score	0.102173 (rank : 44)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	138	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

FGD6_MOUSE
NC score	0.101709 (rank : 45)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	138	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

PKHA5_HUMAN
NC score	0.101496 (rank : 46)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	138	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

DAPP1_HUMAN
NC score	0.096222 (rank : 47)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	138	Target Neighborhood Hits	227	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GNRP_HUMAN
NC score	0.094587 (rank : 48)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	138	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

DDEF1_MOUSE
NC score	0.092942 (rank : 49)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	138	Target Neighborhood Hits	592	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

FGD5_MOUSE
NC score	0.087267 (rank : 50)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	138	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD5_HUMAN
NC score	0.087211 (rank : 51)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	138	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

CEND1_HUMAN
NC score	0.087137 (rank : 52)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	138	Target Neighborhood Hits	284	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

GNRP_MOUSE
NC score	0.084763 (rank : 53)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	138	Target Neighborhood Hits	191	Shared Neighborhood Hits	46
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CYH1_HUMAN
NC score	0.084390 (rank : 54)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	138	Target Neighborhood Hits	184	Shared Neighborhood Hits	62
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.082039 (rank : 55)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	138	Target Neighborhood Hits	176	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

FGD1_HUMAN
NC score	0.079655 (rank : 56)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	138	Target Neighborhood Hits	367	Shared Neighborhood Hits	29
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
NC score	0.079324 (rank : 57)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	138	Target Neighborhood Hits	387	Shared Neighborhood Hits	29
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CYH3_HUMAN
NC score	0.079289 (rank : 58)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	138	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_MOUSE
NC score	0.079255 (rank : 59)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	138	Target Neighborhood Hits	171	Shared Neighborhood Hits	57
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.079253 (rank : 60)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	138	Target Neighborhood Hits	175	Shared Neighborhood Hits	57
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

FGD4_HUMAN
NC score	0.077293 (rank : 61)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	138	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

CEND2_HUMAN
NC score	0.076182 (rank : 62)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	138	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

FGD4_MOUSE
NC score	0.074622 (rank : 63)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	138	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

GAB2_MOUSE
NC score	0.073905 (rank : 64)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	138	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

DDFL1_HUMAN
NC score	0.072813 (rank : 65)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	138	Target Neighborhood Hits	353	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

PKHA4_MOUSE
NC score	0.071700 (rank : 66)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	138	Target Neighborhood Hits	202	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CEND1_MOUSE
NC score	0.070829 (rank : 67)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	138	Target Neighborhood Hits	260	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CENB5_HUMAN
NC score	0.069974 (rank : 68)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	138	Target Neighborhood Hits	395	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

PKHA4_HUMAN
NC score	0.069898 (rank : 69)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	138	Target Neighborhood Hits	283	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DDFL1_MOUSE
NC score	0.069723 (rank : 70)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	138	Target Neighborhood Hits	324	Shared Neighborhood Hits	35
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CENB1_HUMAN
NC score	0.069518 (rank : 71)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	138	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DDEF2_HUMAN
NC score	0.069028 (rank : 72)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	138	Target Neighborhood Hits	599	Shared Neighborhood Hits	43
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PHLB1_MOUSE
NC score	0.069019 (rank : 73)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	138	Target Neighborhood Hits	678	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

DDEF2_MOUSE
NC score	0.068528 (rank : 74)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	138	Target Neighborhood Hits	625	Shared Neighborhood Hits	42
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FARP2_MOUSE
NC score	0.066960 (rank : 75)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	138	Target Neighborhood Hits	209	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
NC score	0.065335 (rank : 76)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	138	Target Neighborhood Hits	240	Shared Neighborhood Hits	36
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GAB2_HUMAN
NC score	0.064829 (rank : 77)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	138	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

FARP1_HUMAN
NC score	0.062745 (rank : 78)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	138	Target Neighborhood Hits	241	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FGD2_MOUSE
NC score	0.062187 (rank : 79)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	138	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

CENB2_HUMAN
NC score	0.061449 (rank : 80)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	138	Target Neighborhood Hits	425	Shared Neighborhood Hits	50
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

FGD3_MOUSE
NC score	0.061438 (rank : 81)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	138	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

CENA2_HUMAN
NC score	0.059594 (rank : 82)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	138	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

FGD2_HUMAN
NC score	0.059186 (rank : 83)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	138	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

PHLB1_HUMAN
NC score	0.058653 (rank : 84)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	138	Target Neighborhood Hits	1038	Shared Neighborhood Hits	56
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

FGD3_HUMAN
NC score	0.057975 (rank : 85)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	138	Target Neighborhood Hits	249	Shared Neighborhood Hits	23
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

PHLB2_MOUSE
NC score	0.057372 (rank : 86)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	138	Target Neighborhood Hits	1016	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_HUMAN
NC score	0.056588 (rank : 87)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	138	Target Neighborhood Hits	964	Shared Neighborhood Hits	51
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

MYO10_HUMAN
NC score	0.056388 (rank : 88)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	138	Target Neighborhood Hits	920	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CENG3_HUMAN
NC score	0.053764 (rank : 89)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	138	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENA1_HUMAN
NC score	0.052727 (rank : 90)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

GAB1_HUMAN
NC score	0.052033 (rank : 91)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	138	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CENG3_MOUSE
NC score	0.051725 (rank : 92)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	138	Target Neighborhood Hits	467	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG1_MOUSE
NC score	0.051409 (rank : 93)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	138	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.050763 (rank : 94)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	138	Target Neighborhood Hits	544	Shared Neighborhood Hits	25
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_MOUSE
NC score	0.049462 (rank : 95)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	138	Target Neighborhood Hits	463	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG2_HUMAN
NC score	0.049337 (rank : 96)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	138	Target Neighborhood Hits	471	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

PREX1_HUMAN
NC score	0.044729 (rank : 97)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	138	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RBBP6_MOUSE
NC score	0.040792 (rank : 98)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	138	Target Neighborhood Hits	1014	Shared Neighborhood Hits	13
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBBP6_HUMAN
NC score	0.038231 (rank : 99)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	138	Target Neighborhood Hits	1135	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SOS1_HUMAN
NC score	0.037801 (rank : 100)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	138	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

DGKH_HUMAN
NC score	0.037176 (rank : 101)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	138	Target Neighborhood Hits	255	Shared Neighborhood Hits	37
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

SOS2_HUMAN
NC score	0.037030 (rank : 102)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	138	Target Neighborhood Hits	193	Shared Neighborhood Hits	21
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

CK060_MOUSE
NC score	0.036660 (rank : 103)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	138	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DB07, Q91Z06, Q9JHT1	Gene names
Domain Architecture	No domain graphic available
Description	UPF0360 protein C11orf60 homolog.

CK060_HUMAN
NC score	0.033960 (rank : 104)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	138	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC8	Gene names	C11orf60, C11orf2
Domain Architecture	No domain graphic available
Description	UPF0360 protein C11orf60.

SOS1_MOUSE
NC score	0.032128 (rank : 105)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	138	Target Neighborhood Hits	281	Shared Neighborhood Hits	19
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

TACC3_MOUSE
NC score	0.030790 (rank : 106)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	138	Target Neighborhood Hits	607	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

ANK2_HUMAN
NC score	0.030602 (rank : 107)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	138	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CCD91_MOUSE
NC score	0.029931 (rank : 108)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	138	Target Neighborhood Hits	699	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD91_HUMAN
NC score	0.027667 (rank : 109)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	138	Target Neighborhood Hits	868	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

SDS3_HUMAN
NC score	0.018220 (rank : 110)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	138	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

PCSK7_HUMAN
NC score	0.017785 (rank : 111)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	138	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
NC score	0.017747 (rank : 112)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	138	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

AL2S8_MOUSE
NC score	0.017650 (rank : 113)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	138	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

CT172_MOUSE
NC score	0.017444 (rank : 114)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	138	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYC5, Q9CYF2, Q9DA26	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172 homolog.

CCD37_HUMAN
NC score	0.016959 (rank : 115)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	138	Target Neighborhood Hits	248	Shared Neighborhood Hits	17
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CUTL1_MOUSE
NC score	0.016915 (rank : 116)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	138	Target Neighborhood Hits	1620	Shared Neighborhood Hits	37
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CUTL1_HUMAN
NC score	0.016868 (rank : 117)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	138	Target Neighborhood Hits	1574	Shared Neighborhood Hits	38
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

MORC2_HUMAN
NC score	0.016743 (rank : 118)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	138	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

K1210_HUMAN
NC score	0.016444 (rank : 119)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	138	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

FRAP_HUMAN
NC score	0.016099 (rank : 120)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	138	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

CASP_MOUSE
NC score	0.016046 (rank : 121)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	138	Target Neighborhood Hits	1152	Shared Neighborhood Hits	31
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
NC score	0.015909 (rank : 122)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	138	Target Neighborhood Hits	1131	Shared Neighborhood Hits	31
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

GOGB1_HUMAN
NC score	0.015082 (rank : 123)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	138	Target Neighborhood Hits	2297	Shared Neighborhood Hits	51
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CMTA1_HUMAN
NC score	0.014060 (rank : 124)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	138	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

FRAP_MOUSE
NC score	0.013781 (rank : 125)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	138	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

UBAP1_HUMAN
NC score	0.013666 (rank : 126)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	138	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

PPRB_MOUSE
NC score	0.013578 (rank : 127)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	138	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

CE152_HUMAN
NC score	0.012907 (rank : 128)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	138	Target Neighborhood Hits	976	Shared Neighborhood Hits	27
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

RBCC1_HUMAN
NC score	0.012002 (rank : 129)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	138	Target Neighborhood Hits	1023	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CP135_HUMAN
NC score	0.011706 (rank : 130)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	138	Target Neighborhood Hits	1290	Shared Neighborhood Hits	33
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
NC score	0.010942 (rank : 131)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	138	Target Neighborhood Hits	1278	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CF060_HUMAN
NC score	0.010859 (rank : 132)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	138	Target Neighborhood Hits	1270	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MYPN_MOUSE
NC score	0.010298 (rank : 133)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	138	Target Neighborhood Hits	421	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

BMX_HUMAN
NC score	0.010185 (rank : 134)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	138	Target Neighborhood Hits	942	Shared Neighborhood Hits	28
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

MY18A_MOUSE
NC score	0.010166 (rank : 135)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	138	Target Neighborhood Hits	1989	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH13_HUMAN
NC score	0.010040 (rank : 136)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	138	Target Neighborhood Hits	1504	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

ATN1_HUMAN
NC score	0.009466 (rank : 137)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	138	Target Neighborhood Hits	676	Shared Neighborhood Hits	16
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BMX_MOUSE
NC score	0.009093 (rank : 138)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	138	Target Neighborhood Hits	912	Shared Neighborhood Hits	28
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

ANGP2_HUMAN
NC score	0.009008 (rank : 139)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	138	Target Neighborhood Hits	400	Shared Neighborhood Hits	17
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

LR37A_HUMAN
NC score	0.008807 (rank : 140)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	138	Target Neighborhood Hits	720	Shared Neighborhood Hits	11
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

K0319_HUMAN
NC score	0.008198 (rank : 141)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

PAX3_HUMAN
NC score	0.008128 (rank : 142)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	138	Target Neighborhood Hits	513	Shared Neighborhood Hits	9
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

ENH3_HUMAN
NC score	0.007847 (rank : 143)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	138	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

PACN2_MOUSE
NC score	0.007401 (rank : 144)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	138	Target Neighborhood Hits	382	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

AKT2_HUMAN
NC score	0.007242 (rank : 145)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	138	Target Neighborhood Hits	878	Shared Neighborhood Hits	31
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

NF2L1_MOUSE
NC score	0.007139 (rank : 146)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	138	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

AKT2_MOUSE
NC score	0.007111 (rank : 147)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	138	Target Neighborhood Hits	875	Shared Neighborhood Hits	31
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

NIPBL_HUMAN
NC score	0.005935 (rank : 148)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	138	Target Neighborhood Hits	1311	Shared Neighborhood Hits	19
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ZN409_HUMAN
NC score	0.005738 (rank : 149)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	138	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

UBP7_HUMAN
NC score	0.004602 (rank : 150)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

PAX3_MOUSE
NC score	0.004493 (rank : 151)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	138	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

WNK2_HUMAN
NC score	0.001421 (rank : 152)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	138	Target Neighborhood Hits	1407	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

LAP2_HUMAN
NC score	0.001229 (rank : 153)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	138	Target Neighborhood Hits	499	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PC11X_HUMAN
NC score	0.000620 (rank : 154)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	138	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

MAST1_HUMAN
NC score	-0.000824 (rank : 155)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	138	Target Neighborhood Hits	1146	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
NC score	-0.001029 (rank : 156)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	138	Target Neighborhood Hits	1123	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).