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Network neighborhood for query Sequence : FOLC_HUMAN

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FOLC_HUMAN
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FOLC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

FOLC_MOUSE
θ value	0 (rank : 2)	NC score	0.995007 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

TERT_HUMAN
θ value	1.38821 (rank : 3)	NC score	0.038661 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O14746, O14783, Q2XS35, Q8N6C3	Gene names	TERT, EST2, TCS1, TRT
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2).

CENPI_HUMAN
θ value	1.81305 (rank : 4)	NC score	0.036384 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q92674, Q5JWZ9, Q96ED0	Gene names	CENPI, FSHPRH1, ICEN19, LRPR1
Domain Architecture	No domain graphic available
Description	Centromere protein I (CENP-I) (Interphase centromere complex protein 19) (Follicle-stimulating hormone primary response protein) (FSH primary response protein 1) (Leucine-rich primary response protein 1).

PKHA4_HUMAN
θ value	5.27518 (rank : 5)	NC score	0.017187 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	283	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DLX5_HUMAN
θ value	6.88961 (rank : 6)	NC score	0.005921 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	405	Shared Neighborhood Hits	3
SwissProt Accessions	P56178, Q9UPL1	Gene names	DLX5
Domain Architecture
Description	Homeobox protein DLX-5.

ZFHX2_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.007697 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	1178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

AMPB_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.009562 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4A4, Q9BVM9, Q9H1D4, Q9NPT7	Gene names	RNPEP, APB
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase).

MOCOS_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.014917 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EN8, Q53GP5, Q8N3A4, Q9NWM7	Gene names	MOCOS
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS) (HMCS).

TBCD4_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.008859 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

Hits sorted by NC score

FOLC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

FOLC_MOUSE
NC score	0.995007 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

TERT_HUMAN
NC score	0.038661 (rank : 3)	θ value	1.38821 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O14746, O14783, Q2XS35, Q8N6C3	Gene names	TERT, EST2, TCS1, TRT
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2).

CENPI_HUMAN
NC score	0.036384 (rank : 4)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q92674, Q5JWZ9, Q96ED0	Gene names	CENPI, FSHPRH1, ICEN19, LRPR1
Domain Architecture	No domain graphic available
Description	Centromere protein I (CENP-I) (Interphase centromere complex protein 19) (Follicle-stimulating hormone primary response protein) (FSH primary response protein 1) (Leucine-rich primary response protein 1).

PKHA4_HUMAN
NC score	0.017187 (rank : 5)	θ value	5.27518 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	283	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

MOCOS_HUMAN
NC score	0.014917 (rank : 6)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EN8, Q53GP5, Q8N3A4, Q9NWM7	Gene names	MOCOS
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS) (HMCS).

AMPB_HUMAN
NC score	0.009562 (rank : 7)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4A4, Q9BVM9, Q9H1D4, Q9NPT7	Gene names	RNPEP, APB
Domain Architecture
Description	Aminopeptidase B (EC 3.4.11.6) (Ap-B) (Arginyl aminopeptidase) (Arginine aminopeptidase).

TBCD4_MOUSE
NC score	0.008859 (rank : 8)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

ZFHX2_HUMAN
NC score	0.007697 (rank : 9)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	1178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

DLX5_HUMAN
NC score	0.005921 (rank : 10)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	405	Shared Neighborhood Hits	3
SwissProt Accessions	P56178, Q9UPL1	Gene names	DLX5
Domain Architecture
Description	Homeobox protein DLX-5.