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Network neighborhood for query Sequence : PTC2_HUMAN

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PTC2_HUMAN
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTC1_HUMAN
θ value	0 (rank : 1)	NC score	0.979882 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC1_MOUSE
θ value	0 (rank : 2)	NC score	0.976847 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC2_MOUSE
θ value	0 (rank : 4)	NC score	0.993294 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

NPC1_HUMAN
θ value	2.96777e-27 (rank : 5)	NC score	0.617970 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	O15118, Q9P130	Gene names	NPC1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPC1_MOUSE
θ value	5.23862e-24 (rank : 6)	NC score	0.602906 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	O35604, O35605	Gene names	Npc1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPCL1_MOUSE
θ value	2.5182e-18 (rank : 7)	NC score	0.563846 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

NPCL1_HUMAN
θ value	4.29542e-18 (rank : 8)	NC score	0.562421 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

SCAP_HUMAN
θ value	1.17247e-07 (rank : 9)	NC score	0.268500 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	368	Shared Neighborhood Hits	18
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

PCDGD_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.020164 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G3, Q9Y5C8	Gene names	PCDHGB1
Domain Architecture
Description	Protocadherin gamma B1 precursor (PCDH-gamma-B1).

3BP1_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.028762 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	376	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

PCDGH_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.019676 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G0, Q9Y5C6	Gene names	PCDHGB5
Domain Architecture
Description	Protocadherin gamma B5 precursor (PCDH-gamma-B5).

PCDGI_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.019161 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5F9, Q9Y5C5	Gene names	PCDHGB6
Domain Architecture
Description	Protocadherin gamma B6 precursor (PCDH-gamma-B6).

CECR2_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.024688 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

HNRL1_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.040146 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.040229 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

PCDGG_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.018342 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UN71, O15099, Q9UN64	Gene names	PCDHGB4, CDH20, FIB2
Domain Architecture
Description	Protocadherin gamma B4 precursor (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin 2).

RANB9_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.031373 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

WASP_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.029884 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	195	Shared Neighborhood Hits	7
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

IRS2_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.022095 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	262	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ULK1_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.002399 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	1214	Shared Neighborhood Hits	19
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

VASP_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.020749 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CXA4_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.009558 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P35212, Q9P106, Q9UBL1, Q9UNA9, Q9UNB0, Q9UNB1, Q9Y5N7	Gene names	GJA4
Domain Architecture
Description	Gap junction alpha-4 protein (Connexin-37) (Cx37).

FOG1_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.004389 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	981	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

TCGAP_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.017645 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NGN3_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.014242 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

SUSD4_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.015076 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

ATX1_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.020165 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

EPN1_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.014816 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

HXD9_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.006336 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	359	Shared Neighborhood Hits	6
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

PCDGE_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.017033 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G2, Q9UN65	Gene names	PCDHGB2
Domain Architecture
Description	Protocadherin gamma B2 precursor (PCDH-gamma-B2).

3BP1_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.022230 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CS007_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.016226 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	464	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DBX1_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.007541 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	346	Shared Neighborhood Hits	5
SwissProt Accessions	P52950	Gene names	Dbx1, Dbx
Domain Architecture
Description	Homeobox protein DBX1.

PLXB1_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.007719 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	360	Shared Neighborhood Hits	9
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

CM003_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.018850 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IX90, Q5VZV5, Q86WR2, Q8NBG1, Q96D22	Gene names	C13orf3, RAMA1
Domain Architecture	No domain graphic available
Description	Protein C13orf3.

CPXM1_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.006859 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

DIAP1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.008799 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	784	Shared Neighborhood Hits	8
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

FOXJ2_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.006073 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GGN_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.017126 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	311	Shared Neighborhood Hits	9
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IMPG1_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.016319 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

K1543_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.021072 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

OAT5_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.009253 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q63ZE4	Gene names	SLC22A10, OAT5
Domain Architecture	No domain graphic available
Description	Solute carrier family 22 member 10 (Organic anion transporter 5).

RX_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.005277 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	423	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

B4GT3_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.015996 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YY2, Q9QY13	Gene names	B4galt3
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

IGHA_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.007487 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P01878	Gene names
Domain Architecture
Description	Ig alpha chain C region.

K1543_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.020576 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SFR15_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.014606 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	368	Shared Neighborhood Hits	7
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

B4GT3_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.014545 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	O60512, O60910, Q9BPZ4, Q9H8T2	Gene names	B4GALT3
Domain Architecture
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

MRP5_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.004966 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

PYGO2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.012967 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

ZN335_HUMAN
θ value	6.88961 (rank : 52)	NC score	-0.000503 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	973	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

EFNB1_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.010105 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P98172	Gene names	EFNB1, EFL-3, EPLG2, LERK2
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L).

EFNB1_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.010300 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P52795	Gene names	Efnb1, Epl2, Eplg2, Lerk2, Stra1
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L) (STRA1 protein) (CEK5 receptor ligand) (CEK5-L).

F8I2_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.012497 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

KCNH3_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.003762 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

MRP5_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.004545 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

SRRM1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.005226 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	966	Shared Neighborhood Hits	11
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAF4_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.009295 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	687	Shared Neighborhood Hits	10
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TLX3_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.003762 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	346	Shared Neighborhood Hits	7
SwissProt Accessions	O55144	Gene names	Tlx3, Hox11l2, Rnx, Tlx1l2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein).

TRPM3_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.008132 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

UBP43_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.004452 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

WASP_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.019918 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

Hits sorted by NC score

PTC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC2_MOUSE
NC score	0.993294 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC1_HUMAN
NC score	0.979882 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC1_MOUSE
NC score	0.976847 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

NPC1_HUMAN
NC score	0.617970 (rank : 5)	θ value	2.96777e-27 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	O15118, Q9P130	Gene names	NPC1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPC1_MOUSE
NC score	0.602906 (rank : 6)	θ value	5.23862e-24 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	O35604, O35605	Gene names	Npc1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPCL1_MOUSE
NC score	0.563846 (rank : 7)	θ value	2.5182e-18 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

NPCL1_HUMAN
NC score	0.562421 (rank : 8)	θ value	4.29542e-18 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

SCAP_HUMAN
NC score	0.268500 (rank : 9)	θ value	1.17247e-07 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	368	Shared Neighborhood Hits	18
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

HNRL1_MOUSE
NC score	0.040229 (rank : 10)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

HNRL1_HUMAN
NC score	0.040146 (rank : 11)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

RANB9_HUMAN
NC score	0.031373 (rank : 12)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

WASP_HUMAN
NC score	0.029884 (rank : 13)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	195	Shared Neighborhood Hits	7
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

3BP1_HUMAN
NC score	0.028762 (rank : 14)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	376	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CECR2_HUMAN
NC score	0.024688 (rank : 15)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

3BP1_MOUSE
NC score	0.022230 (rank : 16)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

IRS2_HUMAN
NC score	0.022095 (rank : 17)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	262	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

K1543_MOUSE
NC score	0.021072 (rank : 18)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

VASP_MOUSE
NC score	0.020749 (rank : 19)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

K1543_HUMAN
NC score	0.020576 (rank : 20)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

ATX1_HUMAN
NC score	0.020165 (rank : 21)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

PCDGD_HUMAN
NC score	0.020164 (rank : 22)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G3, Q9Y5C8	Gene names	PCDHGB1
Domain Architecture
Description	Protocadherin gamma B1 precursor (PCDH-gamma-B1).

WASP_MOUSE
NC score	0.019918 (rank : 23)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

PCDGH_HUMAN
NC score	0.019676 (rank : 24)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G0, Q9Y5C6	Gene names	PCDHGB5
Domain Architecture
Description	Protocadherin gamma B5 precursor (PCDH-gamma-B5).

PCDGI_HUMAN
NC score	0.019161 (rank : 25)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5F9, Q9Y5C5	Gene names	PCDHGB6
Domain Architecture
Description	Protocadherin gamma B6 precursor (PCDH-gamma-B6).

CM003_HUMAN
NC score	0.018850 (rank : 26)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IX90, Q5VZV5, Q86WR2, Q8NBG1, Q96D22	Gene names	C13orf3, RAMA1
Domain Architecture	No domain graphic available
Description	Protein C13orf3.

PCDGG_HUMAN
NC score	0.018342 (rank : 27)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UN71, O15099, Q9UN64	Gene names	PCDHGB4, CDH20, FIB2
Domain Architecture
Description	Protocadherin gamma B4 precursor (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin 2).

TCGAP_MOUSE
NC score	0.017645 (rank : 28)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GGN_MOUSE
NC score	0.017126 (rank : 29)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	311	Shared Neighborhood Hits	9
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PCDGE_HUMAN
NC score	0.017033 (rank : 30)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G2, Q9UN65	Gene names	PCDHGB2
Domain Architecture
Description	Protocadherin gamma B2 precursor (PCDH-gamma-B2).

IMPG1_HUMAN
NC score	0.016319 (rank : 31)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

CS007_MOUSE
NC score	0.016226 (rank : 32)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	464	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

B4GT3_MOUSE
NC score	0.015996 (rank : 33)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YY2, Q9QY13	Gene names	B4galt3
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SUSD4_MOUSE
NC score	0.015076 (rank : 34)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

EPN1_MOUSE
NC score	0.014816 (rank : 35)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

SFR15_HUMAN
NC score	0.014606 (rank : 36)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	368	Shared Neighborhood Hits	7
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

B4GT3_HUMAN
NC score	0.014545 (rank : 37)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	O60512, O60910, Q9BPZ4, Q9H8T2	Gene names	B4GALT3
Domain Architecture
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

NGN3_HUMAN
NC score	0.014242 (rank : 38)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

PYGO2_HUMAN
NC score	0.012967 (rank : 39)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

F8I2_HUMAN
NC score	0.012497 (rank : 40)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

EFNB1_MOUSE
NC score	0.010300 (rank : 41)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P52795	Gene names	Efnb1, Epl2, Eplg2, Lerk2, Stra1
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L) (STRA1 protein) (CEK5 receptor ligand) (CEK5-L).

EFNB1_HUMAN
NC score	0.010105 (rank : 42)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P98172	Gene names	EFNB1, EFL-3, EPLG2, LERK2
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L).

CXA4_HUMAN
NC score	0.009558 (rank : 43)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P35212, Q9P106, Q9UBL1, Q9UNA9, Q9UNB0, Q9UNB1, Q9Y5N7	Gene names	GJA4
Domain Architecture
Description	Gap junction alpha-4 protein (Connexin-37) (Cx37).

TAF4_HUMAN
NC score	0.009295 (rank : 44)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	687	Shared Neighborhood Hits	10
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

OAT5_HUMAN
NC score	0.009253 (rank : 45)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q63ZE4	Gene names	SLC22A10, OAT5
Domain Architecture	No domain graphic available
Description	Solute carrier family 22 member 10 (Organic anion transporter 5).

DIAP1_HUMAN
NC score	0.008799 (rank : 46)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	784	Shared Neighborhood Hits	8
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

TRPM3_HUMAN
NC score	0.008132 (rank : 47)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

PLXB1_HUMAN
NC score	0.007719 (rank : 48)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	360	Shared Neighborhood Hits	9
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

DBX1_MOUSE
NC score	0.007541 (rank : 49)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	346	Shared Neighborhood Hits	5
SwissProt Accessions	P52950	Gene names	Dbx1, Dbx
Domain Architecture
Description	Homeobox protein DBX1.

IGHA_MOUSE
NC score	0.007487 (rank : 50)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P01878	Gene names
Domain Architecture
Description	Ig alpha chain C region.

CPXM1_HUMAN
NC score	0.006859 (rank : 51)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

HXD9_MOUSE
NC score	0.006336 (rank : 52)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	359	Shared Neighborhood Hits	6
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

FOXJ2_MOUSE
NC score	0.006073 (rank : 53)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

RX_HUMAN
NC score	0.005277 (rank : 54)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	423	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SRRM1_MOUSE
NC score	0.005226 (rank : 55)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	966	Shared Neighborhood Hits	11
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MRP5_MOUSE
NC score	0.004966 (rank : 56)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

MRP5_HUMAN
NC score	0.004545 (rank : 57)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

UBP43_MOUSE
NC score	0.004452 (rank : 58)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

FOG1_HUMAN
NC score	0.004389 (rank : 59)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	981	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

KCNH3_HUMAN
NC score	0.003762 (rank : 60)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

TLX3_MOUSE
NC score	0.003762 (rank : 61)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	346	Shared Neighborhood Hits	7
SwissProt Accessions	O55144	Gene names	Tlx3, Hox11l2, Rnx, Tlx1l2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein).

ULK1_MOUSE
NC score	0.002399 (rank : 62)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	1214	Shared Neighborhood Hits	19
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZN335_HUMAN
NC score	-0.000503 (rank : 63)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	973	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.