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Network neighborhood for query Sequence : PTC2_MOUSE

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PTC2_MOUSE
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTC1_HUMAN
θ value	0 (rank : 1)	NC score	0.985733 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC1_MOUSE
θ value	0 (rank : 2)	NC score	0.982680 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC2_HUMAN
θ value	0 (rank : 3)	NC score	0.993294 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

NPC1_HUMAN
θ value	3.28125e-26 (rank : 5)	NC score	0.622419 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	O15118, Q9P130	Gene names	NPC1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPC1_MOUSE
θ value	1.99067e-23 (rank : 6)	NC score	0.607352 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	O35604, O35605	Gene names	Npc1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPCL1_MOUSE
θ value	3.88503e-19 (rank : 7)	NC score	0.569033 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

NPCL1_HUMAN
θ value	1.13037e-18 (rank : 8)	NC score	0.567593 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

SCAP_HUMAN
θ value	1.06045e-08 (rank : 9)	NC score	0.272653 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SIX5_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.009402 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	386	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

B4GT3_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.017264 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YY2, Q9QY13	Gene names	B4galt3
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT3_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.015821 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	O60512, O60910, Q9BPZ4, Q9H8T2	Gene names	B4GALT3
Domain Architecture
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

PANK2_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.009898 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZ23, Q5T7I2, Q8N7Q4, Q8TCR5, Q9BYW5, Q9HAF2	Gene names	PANK2, C20orf48
Domain Architecture
Description	Pantothenate kinase 2, mitochondrial precursor (EC 2.7.1.33) (Pantothenic acid kinase 2) (hPANK2).

PROM1_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.014128 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

SLC2B_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.015668 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

VWF_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.005783 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ATX1_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.010108 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

TRPM3_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.008971 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

UBP25_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.007353 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

AFF2_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.006592 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

Hits sorted by NC score

PTC2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC2_HUMAN
NC score	0.993294 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC1_HUMAN
NC score	0.985733 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC1_MOUSE
NC score	0.982680 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

NPC1_HUMAN
NC score	0.622419 (rank : 5)	θ value	3.28125e-26 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	O15118, Q9P130	Gene names	NPC1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPC1_MOUSE
NC score	0.607352 (rank : 6)	θ value	1.99067e-23 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	O35604, O35605	Gene names	Npc1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPCL1_MOUSE
NC score	0.569033 (rank : 7)	θ value	3.88503e-19 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

NPCL1_HUMAN
NC score	0.567593 (rank : 8)	θ value	1.13037e-18 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

SCAP_HUMAN
NC score	0.272653 (rank : 9)	θ value	1.06045e-08 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

B4GT3_MOUSE
NC score	0.017264 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YY2, Q9QY13	Gene names	B4galt3
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT3_HUMAN
NC score	0.015821 (rank : 11)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	O60512, O60910, Q9BPZ4, Q9H8T2	Gene names	B4GALT3
Domain Architecture
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SLC2B_HUMAN
NC score	0.015668 (rank : 12)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

PROM1_MOUSE
NC score	0.014128 (rank : 13)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

ATX1_MOUSE
NC score	0.010108 (rank : 14)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

PANK2_HUMAN
NC score	0.009898 (rank : 15)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZ23, Q5T7I2, Q8N7Q4, Q8TCR5, Q9BYW5, Q9HAF2	Gene names	PANK2, C20orf48
Domain Architecture
Description	Pantothenate kinase 2, mitochondrial precursor (EC 2.7.1.33) (Pantothenic acid kinase 2) (hPANK2).

SIX5_HUMAN
NC score	0.009402 (rank : 16)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	386	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

TRPM3_HUMAN
NC score	0.008971 (rank : 17)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

UBP25_HUMAN
NC score	0.007353 (rank : 18)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

AFF2_MOUSE
NC score	0.006592 (rank : 19)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

VWF_MOUSE
NC score	0.005783 (rank : 20)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].