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Network neighborhood for query Sequence : WRN_MOUSE

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WRN_MOUSE
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WRN_HUMAN
θ value	0 (rank : 1)	NC score	0.960445 (rank : 2)
Query Neighborhood Hits	295	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	295	Target Neighborhood Hits	295	Shared Neighborhood Hits	295
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_MOUSE
θ value	3.03575e-64 (rank : 3)	NC score	0.855730 (rank : 3)
Query Neighborhood Hits	295	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
θ value	8.83269e-64 (rank : 4)	NC score	0.850749 (rank : 4)
Query Neighborhood Hits	295	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
θ value	6.55044e-59 (rank : 5)	NC score	0.811795 (rank : 7)
Query Neighborhood Hits	295	Target Neighborhood Hits	390	Shared Neighborhood Hits	87
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

BLM_MOUSE
θ value	2.7521e-57 (rank : 6)	NC score	0.820477 (rank : 5)
Query Neighborhood Hits	295	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
θ value	2.18062e-54 (rank : 7)	NC score	0.814468 (rank : 6)
Query Neighborhood Hits	295	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ4_HUMAN
θ value	7.27602e-42 (rank : 8)	NC score	0.788967 (rank : 8)
Query Neighborhood Hits	295	Target Neighborhood Hits	177	Shared Neighborhood Hits	82
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	4.88048e-38 (rank : 9)	NC score	0.783924 (rank : 9)
Query Neighborhood Hits	295	Target Neighborhood Hits	206	Shared Neighborhood Hits	84
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX46_MOUSE
θ value	1.133e-10 (rank : 10)	NC score	0.497752 (rank : 10)
Query Neighborhood Hits	295	Target Neighborhood Hits	358	Shared Neighborhood Hits	124
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX46_HUMAN
θ value	5.62301e-10 (rank : 11)	NC score	0.497361 (rank : 11)
Query Neighborhood Hits	295	Target Neighborhood Hits	357	Shared Neighborhood Hits	125
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX3Y_MOUSE
θ value	6.21693e-09 (rank : 12)	NC score	0.472601 (rank : 27)
Query Neighborhood Hits	295	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX53_HUMAN
θ value	8.11959e-09 (rank : 13)	NC score	0.456264 (rank : 34)
Query Neighborhood Hits	295	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

EXDL2_HUMAN
θ value	1.38499e-08 (rank : 14)	NC score	0.241808 (rank : 78)
Query Neighborhood Hits	295	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

DDX3X_MOUSE
θ value	5.26297e-08 (rank : 15)	NC score	0.477095 (rank : 18)
Query Neighborhood Hits	295	Target Neighborhood Hits	117	Shared Neighborhood Hits	78
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX41_HUMAN
θ value	5.26297e-08 (rank : 16)	NC score	0.478508 (rank : 17)
Query Neighborhood Hits	295	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	5.26297e-08 (rank : 17)	NC score	0.476905 (rank : 19)
Query Neighborhood Hits	295	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

PL10_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.473397 (rank : 26)
Query Neighborhood Hits	295	Target Neighborhood Hits	120	Shared Neighborhood Hits	76
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
θ value	6.87365e-08 (rank : 19)	NC score	0.475462 (rank : 20)
Query Neighborhood Hits	295	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_HUMAN
θ value	1.17247e-07 (rank : 20)	NC score	0.474320 (rank : 25)
Query Neighborhood Hits	295	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX6_HUMAN
θ value	1.17247e-07 (rank : 21)	NC score	0.475323 (rank : 21)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	1.17247e-07 (rank : 22)	NC score	0.475231 (rank : 22)
Query Neighborhood Hits	295	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

EXDL2_MOUSE
θ value	1.53129e-07 (rank : 23)	NC score	0.237441 (rank : 79)
Query Neighborhood Hits	295	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

DDX17_HUMAN
θ value	2.61198e-07 (rank : 24)	NC score	0.493596 (rank : 13)
Query Neighborhood Hits	295	Target Neighborhood Hits	104	Shared Neighborhood Hits	75
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	2.61198e-07 (rank : 25)	NC score	0.493633 (rank : 12)
Query Neighborhood Hits	295	Target Neighborhood Hits	105	Shared Neighborhood Hits	74
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX48_HUMAN
θ value	2.61198e-07 (rank : 26)	NC score	0.465199 (rank : 31)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	2.61198e-07 (rank : 27)	NC score	0.464999 (rank : 32)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX52_MOUSE
θ value	7.59969e-07 (rank : 28)	NC score	0.474867 (rank : 23)
Query Neighborhood Hits	295	Target Neighborhood Hits	101	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX43_HUMAN
θ value	9.92553e-07 (rank : 29)	NC score	0.483834 (rank : 16)
Query Neighborhood Hits	295	Target Neighborhood Hits	120	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX52_HUMAN
θ value	1.69304e-06 (rank : 30)	NC score	0.474486 (rank : 24)
Query Neighborhood Hits	295	Target Neighborhood Hits	107	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX23_HUMAN
θ value	8.40245e-06 (rank : 31)	NC score	0.470330 (rank : 29)
Query Neighborhood Hits	295	Target Neighborhood Hits	486	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX5_HUMAN
θ value	1.09739e-05 (rank : 32)	NC score	0.489006 (rank : 15)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	1.09739e-05 (rank : 33)	NC score	0.489393 (rank : 14)
Query Neighborhood Hits	295	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX50_HUMAN
θ value	1.87187e-05 (rank : 34)	NC score	0.470366 (rank : 28)
Query Neighborhood Hits	295	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	1.87187e-05 (rank : 35)	NC score	0.469966 (rank : 30)
Query Neighborhood Hits	295	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_HUMAN
θ value	0.000121331 (rank : 36)	NC score	0.462895 (rank : 33)
Query Neighborhood Hits	295	Target Neighborhood Hits	308	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX27_MOUSE
θ value	0.000121331 (rank : 37)	NC score	0.446614 (rank : 42)
Query Neighborhood Hits	295	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	0.000158464 (rank : 38)	NC score	0.445662 (rank : 43)
Query Neighborhood Hits	295	Target Neighborhood Hits	197	Shared Neighborhood Hits	95
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

IF4A1_HUMAN
θ value	0.000158464 (rank : 39)	NC score	0.449787 (rank : 39)
Query Neighborhood Hits	295	Target Neighborhood Hits	106	Shared Neighborhood Hits	75
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	0.000158464 (rank : 40)	NC score	0.449787 (rank : 40)
Query Neighborhood Hits	295	Target Neighborhood Hits	106	Shared Neighborhood Hits	75
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX49_MOUSE
θ value	0.00020696 (rank : 41)	NC score	0.452166 (rank : 36)
Query Neighborhood Hits	295	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

IF4A2_HUMAN
θ value	0.00020696 (rank : 42)	NC score	0.450557 (rank : 37)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	0.00020696 (rank : 43)	NC score	0.450557 (rank : 38)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX39_HUMAN
θ value	0.00035302 (rank : 44)	NC score	0.442971 (rank : 46)
Query Neighborhood Hits	295	Target Neighborhood Hits	94	Shared Neighborhood Hits	76
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX54_HUMAN
θ value	0.000602161 (rank : 45)	NC score	0.435904 (rank : 49)
Query Neighborhood Hits	295	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
θ value	0.000602161 (rank : 46)	NC score	0.438735 (rank : 48)
Query Neighborhood Hits	295	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX39_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.441013 (rank : 47)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DD19A_HUMAN
θ value	0.00102713 (rank : 48)	NC score	0.408146 (rank : 62)
Query Neighborhood Hits	295	Target Neighborhood Hits	107	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	0.00102713 (rank : 49)	NC score	0.407472 (rank : 64)
Query Neighborhood Hits	295	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	0.00102713 (rank : 50)	NC score	0.407651 (rank : 63)
Query Neighborhood Hits	295	Target Neighborhood Hits	109	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX21_MOUSE
θ value	0.00102713 (rank : 51)	NC score	0.454308 (rank : 35)
Query Neighborhood Hits	295	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX24_HUMAN
θ value	0.00102713 (rank : 52)	NC score	0.429309 (rank : 55)
Query Neighborhood Hits	295	Target Neighborhood Hits	190	Shared Neighborhood Hits	88
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_MOUSE
θ value	0.00134147 (rank : 53)	NC score	0.431007 (rank : 54)
Query Neighborhood Hits	295	Target Neighborhood Hits	147	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX31_HUMAN
θ value	0.00134147 (rank : 54)	NC score	0.422004 (rank : 57)
Query Neighborhood Hits	295	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX51_MOUSE
θ value	0.00228821 (rank : 55)	NC score	0.414092 (rank : 59)
Query Neighborhood Hits	295	Target Neighborhood Hits	130	Shared Neighborhood Hits	78
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

UAP56_HUMAN
θ value	0.00298849 (rank : 56)	NC score	0.433664 (rank : 50)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.00298849 (rank : 57)	NC score	0.433517 (rank : 51)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX49_HUMAN
θ value	0.00390308 (rank : 58)	NC score	0.448355 (rank : 41)
Query Neighborhood Hits	295	Target Neighborhood Hits	223	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX4_HUMAN
θ value	0.00509761 (rank : 59)	NC score	0.444464 (rank : 44)
Query Neighborhood Hits	295	Target Neighborhood Hits	123	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	0.00509761 (rank : 60)	NC score	0.443767 (rank : 45)
Query Neighborhood Hits	295	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX1_HUMAN
θ value	0.00665767 (rank : 61)	NC score	0.421768 (rank : 58)
Query Neighborhood Hits	295	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	0.00665767 (rank : 62)	NC score	0.424680 (rank : 56)
Query Neighborhood Hits	295	Target Neighborhood Hits	112	Shared Neighborhood Hits	74
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

HELC1_HUMAN
θ value	0.00665767 (rank : 63)	NC score	0.166426 (rank : 88)
Query Neighborhood Hits	295	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DDX51_HUMAN
θ value	0.0113563 (rank : 64)	NC score	0.411891 (rank : 61)
Query Neighborhood Hits	295	Target Neighborhood Hits	332	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

GOGA4_HUMAN
θ value	0.0113563 (rank : 65)	NC score	0.064381 (rank : 101)
Query Neighborhood Hits	295	Target Neighborhood Hits	2034	Shared Neighborhood Hits	137
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

DDX25_MOUSE
θ value	0.0148317 (rank : 66)	NC score	0.401890 (rank : 70)
Query Neighborhood Hits	295	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

PCDA8_HUMAN
θ value	0.0148317 (rank : 67)	NC score	0.023425 (rank : 253)
Query Neighborhood Hits	295	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PCDAB_HUMAN
θ value	0.0148317 (rank : 68)	NC score	0.023316 (rank : 255)
Query Neighborhood Hits	295	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

SFPQ_HUMAN
θ value	0.0148317 (rank : 69)	NC score	0.053882 (rank : 126)
Query Neighborhood Hits	295	Target Neighborhood Hits	986	Shared Neighborhood Hits	73
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

VDP_MOUSE
θ value	0.0148317 (rank : 70)	NC score	0.082304 (rank : 92)
Query Neighborhood Hits	295	Target Neighborhood Hits	469	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

DDX25_HUMAN
θ value	0.0193708 (rank : 71)	NC score	0.403773 (rank : 68)
Query Neighborhood Hits	295	Target Neighborhood Hits	93	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

KTN1_MOUSE
θ value	0.0193708 (rank : 72)	NC score	0.062172 (rank : 102)
Query Neighborhood Hits	295	Target Neighborhood Hits	1324	Shared Neighborhood Hits	110
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SFPQ_MOUSE
θ value	0.0193708 (rank : 73)	NC score	0.053325 (rank : 129)
Query Neighborhood Hits	295	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

ATX2_HUMAN
θ value	0.0252991 (rank : 74)	NC score	0.055969 (rank : 115)
Query Neighborhood Hits	295	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

JHD2C_MOUSE
θ value	0.0431538 (rank : 75)	NC score	0.033259 (rank : 210)
Query Neighborhood Hits	295	Target Neighborhood Hits	297	Shared Neighborhood Hits	35
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

SMRCD_HUMAN
θ value	0.0431538 (rank : 76)	NC score	0.027950 (rank : 236)
Query Neighborhood Hits	295	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

DMP1_HUMAN
θ value	0.0563607 (rank : 77)	NC score	0.080850 (rank : 93)
Query Neighborhood Hits	295	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DDX28_MOUSE
θ value	0.0736092 (rank : 78)	NC score	0.413004 (rank : 60)
Query Neighborhood Hits	295	Target Neighborhood Hits	112	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

MYH13_HUMAN
θ value	0.0736092 (rank : 79)	NC score	0.044714 (rank : 166)
Query Neighborhood Hits	295	Target Neighborhood Hits	1504	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PEPL_HUMAN
θ value	0.0961366 (rank : 80)	NC score	0.057815 (rank : 110)
Query Neighborhood Hits	295	Target Neighborhood Hits	1141	Shared Neighborhood Hits	105
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

RB6I2_MOUSE
θ value	0.0961366 (rank : 81)	NC score	0.055848 (rank : 116)
Query Neighborhood Hits	295	Target Neighborhood Hits	1433	Shared Neighborhood Hits	112
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

VDP_HUMAN
θ value	0.0961366 (rank : 82)	NC score	0.073417 (rank : 98)
Query Neighborhood Hits	295	Target Neighborhood Hits	645	Shared Neighborhood Hits	73
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ZW10_MOUSE
θ value	0.0961366 (rank : 83)	NC score	0.056813 (rank : 111)
Query Neighborhood Hits	295	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

ATX2_MOUSE
θ value	0.125558 (rank : 84)	NC score	0.055624 (rank : 119)
Query Neighborhood Hits	295	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SPT5H_HUMAN
θ value	0.125558 (rank : 85)	NC score	0.047179 (rank : 159)
Query Neighborhood Hits	295	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

AN32B_MOUSE
θ value	0.163984 (rank : 86)	NC score	0.036657 (rank : 197)
Query Neighborhood Hits	295	Target Neighborhood Hits	236	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

C8AP2_MOUSE
θ value	0.163984 (rank : 87)	NC score	0.043326 (rank : 173)
Query Neighborhood Hits	295	Target Neighborhood Hits	405	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CBP_MOUSE
θ value	0.163984 (rank : 88)	NC score	0.033146 (rank : 211)
Query Neighborhood Hits	295	Target Neighborhood Hits	1051	Shared Neighborhood Hits	53
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HMMR_MOUSE
θ value	0.21417 (rank : 89)	NC score	0.054312 (rank : 124)
Query Neighborhood Hits	295	Target Neighborhood Hits	1178	Shared Neighborhood Hits	103
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ATBF1_HUMAN
θ value	0.279714 (rank : 90)	NC score	0.014002 (rank : 286)
Query Neighborhood Hits	295	Target Neighborhood Hits	1547	Shared Neighborhood Hits	34
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MRCKA_HUMAN
θ value	0.279714 (rank : 91)	NC score	0.025062 (rank : 245)
Query Neighborhood Hits	295	Target Neighborhood Hits	1999	Shared Neighborhood Hits	99
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

TRHY_HUMAN
θ value	0.279714 (rank : 92)	NC score	0.054725 (rank : 121)
Query Neighborhood Hits	295	Target Neighborhood Hits	1385	Shared Neighborhood Hits	104
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

U520_HUMAN
θ value	0.279714 (rank : 93)	NC score	0.175935 (rank : 84)
Query Neighborhood Hits	295	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

EDD1_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.028942 (rank : 232)
Query Neighborhood Hits	295	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

IF2P_HUMAN
θ value	0.365318 (rank : 95)	NC score	0.060507 (rank : 104)
Query Neighborhood Hits	295	Target Neighborhood Hits	889	Shared Neighborhood Hits	99
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MRCKB_HUMAN
θ value	0.365318 (rank : 96)	NC score	0.030332 (rank : 223)
Query Neighborhood Hits	295	Target Neighborhood Hits	2239	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
θ value	0.365318 (rank : 97)	NC score	0.030093 (rank : 225)
Query Neighborhood Hits	295	Target Neighborhood Hits	2180	Shared Neighborhood Hits	115
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYT1L_HUMAN
θ value	0.365318 (rank : 98)	NC score	0.049546 (rank : 154)
Query Neighborhood Hits	295	Target Neighborhood Hits	471	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

RPGR1_MOUSE
θ value	0.365318 (rank : 99)	NC score	0.054588 (rank : 122)
Query Neighborhood Hits	295	Target Neighborhood Hits	713	Shared Neighborhood Hits	90
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RYR1_HUMAN
θ value	0.365318 (rank : 100)	NC score	0.030765 (rank : 219)
Query Neighborhood Hits	295	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

CDT1_MOUSE
θ value	0.47712 (rank : 101)	NC score	0.032738 (rank : 214)
Query Neighborhood Hits	295	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

DDX20_MOUSE
θ value	0.47712 (rank : 102)	NC score	0.404485 (rank : 67)
Query Neighborhood Hits	295	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

HIRP3_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.050288 (rank : 151)
Query Neighborhood Hits	295	Target Neighborhood Hits	323	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

IFIH1_MOUSE
θ value	0.47712 (rank : 104)	NC score	0.172204 (rank : 86)
Query Neighborhood Hits	295	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

RB6I2_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.057886 (rank : 109)
Query Neighborhood Hits	295	Target Neighborhood Hits	1584	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SLK_MOUSE
θ value	0.47712 (rank : 106)	NC score	0.017002 (rank : 273)
Query Neighborhood Hits	295	Target Neighborhood Hits	1798	Shared Neighborhood Hits	116
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SMC1A_HUMAN
θ value	0.47712 (rank : 107)	NC score	0.055620 (rank : 120)
Query Neighborhood Hits	295	Target Neighborhood Hits	1346	Shared Neighborhood Hits	119
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.47712 (rank : 108)	NC score	0.056460 (rank : 113)
Query Neighborhood Hits	295	Target Neighborhood Hits	1384	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

ATBF1_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.015877 (rank : 277)
Query Neighborhood Hits	295	Target Neighborhood Hits	1841	Shared Neighborhood Hits	63
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CEP35_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.052133 (rank : 137)
Query Neighborhood Hits	295	Target Neighborhood Hits	811	Shared Neighborhood Hits	97
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CP135_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.053075 (rank : 131)
Query Neighborhood Hits	295	Target Neighborhood Hits	1290	Shared Neighborhood Hits	101
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DDX20_HUMAN
θ value	0.62314 (rank : 112)	NC score	0.406839 (rank : 65)
Query Neighborhood Hits	295	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

ESPL1_MOUSE
θ value	0.62314 (rank : 113)	NC score	0.032912 (rank : 212)
Query Neighborhood Hits	295	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

PELP1_MOUSE
θ value	0.62314 (rank : 114)	NC score	0.044171 (rank : 169)
Query Neighborhood Hits	295	Target Neighborhood Hits	709	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SMRC2_MOUSE
θ value	0.62314 (rank : 115)	NC score	0.043632 (rank : 171)
Query Neighborhood Hits	295	Target Neighborhood Hits	487	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TRI44_MOUSE
θ value	0.62314 (rank : 116)	NC score	0.032193 (rank : 216)
Query Neighborhood Hits	295	Target Neighborhood Hits	327	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

UBF1_MOUSE
θ value	0.62314 (rank : 117)	NC score	0.035443 (rank : 206)
Query Neighborhood Hits	295	Target Neighborhood Hits	419	Shared Neighborhood Hits	50
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

EDD1_MOUSE
θ value	0.813845 (rank : 118)	NC score	0.026801 (rank : 241)
Query Neighborhood Hits	295	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

GOG8A_HUMAN
θ value	0.813845 (rank : 119)	NC score	0.052993 (rank : 132)
Query Neighborhood Hits	295	Target Neighborhood Hits	635	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGB1_HUMAN
θ value	0.813845 (rank : 120)	NC score	0.061242 (rank : 103)
Query Neighborhood Hits	295	Target Neighborhood Hits	2297	Shared Neighborhood Hits	142
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HTSF1_MOUSE
θ value	0.813845 (rank : 121)	NC score	0.042412 (rank : 181)
Query Neighborhood Hits	295	Target Neighborhood Hits	425	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MYST4_HUMAN
θ value	0.813845 (rank : 122)	NC score	0.036406 (rank : 198)
Query Neighborhood Hits	295	Target Neighborhood Hits	671	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYT1_HUMAN
θ value	0.813845 (rank : 123)	NC score	0.047660 (rank : 156)
Query Neighborhood Hits	295	Target Neighborhood Hits	475	Shared Neighborhood Hits	76
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

PCDA3_HUMAN
θ value	0.813845 (rank : 124)	NC score	0.020416 (rank : 262)
Query Neighborhood Hits	295	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

PEPL_MOUSE
θ value	0.813845 (rank : 125)	NC score	0.056480 (rank : 112)
Query Neighborhood Hits	295	Target Neighborhood Hits	1105	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PPIG_HUMAN
θ value	0.813845 (rank : 126)	NC score	0.039825 (rank : 191)
Query Neighborhood Hits	295	Target Neighborhood Hits	670	Shared Neighborhood Hits	91
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TCF8_MOUSE
θ value	0.813845 (rank : 127)	NC score	0.002353 (rank : 316)
Query Neighborhood Hits	295	Target Neighborhood Hits	1067	Shared Neighborhood Hits	50
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

ZCHC6_HUMAN
θ value	0.813845 (rank : 128)	NC score	0.024874 (rank : 248)
Query Neighborhood Hits	295	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

CLSPN_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.047288 (rank : 158)
Query Neighborhood Hits	295	Target Neighborhood Hits	433	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

DHX16_HUMAN
θ value	1.06291 (rank : 130)	NC score	0.021785 (rank : 257)
Query Neighborhood Hits	295	Target Neighborhood Hits	356	Shared Neighborhood Hits	57
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

MYH6_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.042740 (rank : 177)
Query Neighborhood Hits	295	Target Neighborhood Hits	1426	Shared Neighborhood Hits	104
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYST3_HUMAN
θ value	1.06291 (rank : 132)	NC score	0.035686 (rank : 204)
Query Neighborhood Hits	295	Target Neighborhood Hits	772	Shared Neighborhood Hits	69
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NEK1_HUMAN
θ value	1.06291 (rank : 133)	NC score	0.006610 (rank : 309)
Query Neighborhood Hits	295	Target Neighborhood Hits	1129	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

PCDA1_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.020206 (rank : 264)
Query Neighborhood Hits	295	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

PCNT_HUMAN
θ value	1.06291 (rank : 135)	NC score	0.052990 (rank : 133)
Query Neighborhood Hits	295	Target Neighborhood Hits	1551	Shared Neighborhood Hits	110
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

SMRC2_HUMAN
θ value	1.06291 (rank : 136)	NC score	0.040990 (rank : 187)
Query Neighborhood Hits	295	Target Neighborhood Hits	499	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

CE290_HUMAN
θ value	1.38821 (rank : 137)	NC score	0.051526 (rank : 145)
Query Neighborhood Hits	295	Target Neighborhood Hits	1553	Shared Neighborhood Hits	111
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

IWS1_MOUSE
θ value	1.38821 (rank : 138)	NC score	0.057983 (rank : 108)
Query Neighborhood Hits	295	Target Neighborhood Hits	1258	Shared Neighborhood Hits	106
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KCAB1_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.014450 (rank : 282)
Query Neighborhood Hits	295	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q14722, Q13031, Q13302, Q16547, Q99869	Gene names	KCNAB1, KCNA1B
Domain Architecture
Description	Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1) (Kv-beta-1).

KTN1_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.053850 (rank : 127)
Query Neighborhood Hits	295	Target Neighborhood Hits	1197	Shared Neighborhood Hits	98
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MATR3_MOUSE
θ value	1.38821 (rank : 141)	NC score	0.046766 (rank : 162)
Query Neighborhood Hits	295	Target Neighborhood Hits	321	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MYST3_MOUSE
θ value	1.38821 (rank : 142)	NC score	0.037010 (rank : 195)
Query Neighborhood Hits	295	Target Neighborhood Hits	688	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PCDA6_HUMAN
θ value	1.38821 (rank : 143)	NC score	0.020383 (rank : 263)
Query Neighborhood Hits	295	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

PCDAD_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.019909 (rank : 266)
Query Neighborhood Hits	295	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

RPTN_MOUSE
θ value	1.38821 (rank : 145)	NC score	0.036966 (rank : 196)
Query Neighborhood Hits	295	Target Neighborhood Hits	650	Shared Neighborhood Hits	82
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SETD2_HUMAN
θ value	1.38821 (rank : 146)	NC score	0.026815 (rank : 240)
Query Neighborhood Hits	295	Target Neighborhood Hits	412	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SLK_HUMAN
θ value	1.38821 (rank : 147)	NC score	0.016128 (rank : 276)
Query Neighborhood Hits	295	Target Neighborhood Hits	1775	Shared Neighborhood Hits	108
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SPT5H_MOUSE
θ value	1.38821 (rank : 148)	NC score	0.040584 (rank : 189)
Query Neighborhood Hits	295	Target Neighborhood Hits	437	Shared Neighborhood Hits	30
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

AKAP9_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.050651 (rank : 148)
Query Neighborhood Hits	295	Target Neighborhood Hits	1710	Shared Neighborhood Hits	118
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR26_MOUSE
θ value	1.81305 (rank : 150)	NC score	0.044235 (rank : 168)
Query Neighborhood Hits	295	Target Neighborhood Hits	1554	Shared Neighborhood Hits	114
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CD2L1_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.009259 (rank : 296)
Query Neighborhood Hits	295	Target Neighborhood Hits	1467	Shared Neighborhood Hits	96
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CN145_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.050553 (rank : 149)
Query Neighborhood Hits	295	Target Neighborhood Hits	1196	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

EXO1_HUMAN
θ value	1.81305 (rank : 153)	NC score	0.023482 (rank : 252)
Query Neighborhood Hits	295	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

FA50A_MOUSE
θ value	1.81305 (rank : 154)	NC score	0.036153 (rank : 199)
Query Neighborhood Hits	295	Target Neighborhood Hits	293	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

FANCM_MOUSE
θ value	1.81305 (rank : 155)	NC score	0.198269 (rank : 81)
Query Neighborhood Hits	295	Target Neighborhood Hits	177	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

FNBP2_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.014046 (rank : 285)
Query Neighborhood Hits	295	Target Neighborhood Hits	432	Shared Neighborhood Hits	37
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

LUZP1_HUMAN
θ value	1.81305 (rank : 157)	NC score	0.046960 (rank : 160)
Query Neighborhood Hits	295	Target Neighborhood Hits	739	Shared Neighborhood Hits	79
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MDN1_HUMAN
θ value	1.81305 (rank : 158)	NC score	0.050773 (rank : 147)
Query Neighborhood Hits	295	Target Neighborhood Hits	662	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PININ_HUMAN
θ value	1.81305 (rank : 159)	NC score	0.058241 (rank : 107)
Query Neighborhood Hits	295	Target Neighborhood Hits	753	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

TOM1_MOUSE
θ value	1.81305 (rank : 160)	NC score	0.014711 (rank : 281)
Query Neighborhood Hits	295	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

AIM1_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.014398 (rank : 284)
Query Neighborhood Hits	295	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

CCD39_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.050294 (rank : 150)
Query Neighborhood Hits	295	Target Neighborhood Hits	868	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CHD1_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.025541 (rank : 243)
Query Neighborhood Hits	295	Target Neighborhood Hits	337	Shared Neighborhood Hits	49
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CT2NL_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.059699 (rank : 106)
Query Neighborhood Hits	295	Target Neighborhood Hits	1059	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DIAP2_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.018229 (rank : 269)
Query Neighborhood Hits	295	Target Neighborhood Hits	342	Shared Neighborhood Hits	45
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

G7C_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.017991 (rank : 272)
Query Neighborhood Hits	295	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

GCC2_MOUSE
θ value	2.36792 (rank : 167)	NC score	0.053926 (rank : 125)
Query Neighborhood Hits	295	Target Neighborhood Hits	1619	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA4_MOUSE
θ value	2.36792 (rank : 168)	NC score	0.055787 (rank : 118)
Query Neighborhood Hits	295	Target Neighborhood Hits	1939	Shared Neighborhood Hits	135
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

ITSN1_HUMAN
θ value	2.36792 (rank : 169)	NC score	0.028960 (rank : 231)
Query Neighborhood Hits	295	Target Neighborhood Hits	1757	Shared Neighborhood Hits	120
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

JHD3C_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.009485 (rank : 295)
Query Neighborhood Hits	295	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

K1C14_MOUSE
θ value	2.36792 (rank : 171)	NC score	0.018363 (rank : 268)
Query Neighborhood Hits	295	Target Neighborhood Hits	501	Shared Neighborhood Hits	66
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

MATR3_HUMAN
θ value	2.36792 (rank : 172)	NC score	0.042666 (rank : 179)
Query Neighborhood Hits	295	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NUP54_HUMAN
θ value	2.36792 (rank : 173)	NC score	0.036015 (rank : 201)
Query Neighborhood Hits	295	Target Neighborhood Hits	93	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

PCDAC_HUMAN
θ value	2.36792 (rank : 174)	NC score	0.020043 (rank : 265)
Query Neighborhood Hits	295	Target Neighborhood Hits	200	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN75, O75278	Gene names	PCDHA12
Domain Architecture
Description	Protocadherin alpha 12 precursor (PCDH-alpha12).

TRI44_HUMAN
θ value	2.36792 (rank : 175)	NC score	0.030315 (rank : 224)
Query Neighborhood Hits	295	Target Neighborhood Hits	393	Shared Neighborhood Hits	44
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

CBP_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.030361 (rank : 222)
Query Neighborhood Hits	295	Target Neighborhood Hits	941	Shared Neighborhood Hits	44
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CK5P2_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.055823 (rank : 117)
Query Neighborhood Hits	295	Target Neighborhood Hits	1433	Shared Neighborhood Hits	125
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CNGA3_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.007949 (rank : 305)
Query Neighborhood Hits	295	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

DDX28_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.395828 (rank : 71)
Query Neighborhood Hits	295	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DMP1_MOUSE
θ value	3.0926 (rank : 180)	NC score	0.048039 (rank : 155)
Query Neighborhood Hits	295	Target Neighborhood Hits	498	Shared Neighborhood Hits	66
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

MYH8_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.043588 (rank : 172)
Query Neighborhood Hits	295	Target Neighborhood Hits	1610	Shared Neighborhood Hits	118
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYO6_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.029049 (rank : 230)
Query Neighborhood Hits	295	Target Neighborhood Hits	727	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

NEK1_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.007515 (rank : 308)
Query Neighborhood Hits	295	Target Neighborhood Hits	1311	Shared Neighborhood Hits	85
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

PIBF1_HUMAN
θ value	3.0926 (rank : 184)	NC score	0.052220 (rank : 135)
Query Neighborhood Hits	295	Target Neighborhood Hits	1041	Shared Neighborhood Hits	100
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

ROCK1_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.023318 (rank : 254)
Query Neighborhood Hits	295	Target Neighborhood Hits	2000	Shared Neighborhood Hits	106
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SAFB2_HUMAN
θ value	3.0926 (rank : 186)	NC score	0.035118 (rank : 208)
Query Neighborhood Hits	295	Target Neighborhood Hits	720	Shared Neighborhood Hits	81
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SKIV2_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.091737 (rank : 90)
Query Neighborhood Hits	295	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SMC2_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.046039 (rank : 165)
Query Neighborhood Hits	295	Target Neighborhood Hits	1131	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

APBB2_HUMAN
θ value	4.03905 (rank : 189)	NC score	0.009976 (rank : 294)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

BMS1_HUMAN
θ value	4.03905 (rank : 190)	NC score	0.025312 (rank : 244)
Query Neighborhood Hits	295	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CTRO_HUMAN
θ value	4.03905 (rank : 191)	NC score	0.024745 (rank : 250)
Query Neighborhood Hits	295	Target Neighborhood Hits	2092	Shared Neighborhood Hits	107
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ENAH_HUMAN
θ value	4.03905 (rank : 192)	NC score	0.035282 (rank : 207)
Query Neighborhood Hits	295	Target Neighborhood Hits	784	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ESPL1_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.027700 (rank : 238)
Query Neighborhood Hits	295	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GOGA6_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.046589 (rank : 163)
Query Neighborhood Hits	295	Target Neighborhood Hits	1007	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

IWS1_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.056448 (rank : 114)
Query Neighborhood Hits	295	Target Neighborhood Hits	1241	Shared Neighborhood Hits	114
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JADE1_MOUSE
θ value	4.03905 (rank : 196)	NC score	0.010424 (rank : 291)
Query Neighborhood Hits	295	Target Neighborhood Hits	160	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

K0423_MOUSE
θ value	4.03905 (rank : 197)	NC score	0.015118 (rank : 279)
Query Neighborhood Hits	295	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MYH2_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.041816 (rank : 183)
Query Neighborhood Hits	295	Target Neighborhood Hits	1491	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH6_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.042769 (rank : 176)
Query Neighborhood Hits	295	Target Neighborhood Hits	1501	Shared Neighborhood Hits	106
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYT1L_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.042586 (rank : 180)
Query Neighborhood Hits	295	Target Neighborhood Hits	461	Shared Neighborhood Hits	66
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

MYT1_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.038562 (rank : 192)
Query Neighborhood Hits	295	Target Neighborhood Hits	385	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NIPBL_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.051985 (rank : 140)
Query Neighborhood Hits	295	Target Neighborhood Hits	1311	Shared Neighborhood Hits	112
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	4.03905 (rank : 203)	NC score	0.047504 (rank : 157)
Query Neighborhood Hits	295	Target Neighborhood Hits	1041	Shared Neighborhood Hits	87
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SKI_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.032673 (rank : 215)
Query Neighborhood Hits	295	Target Neighborhood Hits	423	Shared Neighborhood Hits	60
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

UBP8_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.020982 (rank : 259)
Query Neighborhood Hits	295	Target Neighborhood Hits	751	Shared Neighborhood Hits	86
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

AN32A_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.024967 (rank : 246)
Query Neighborhood Hits	295	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	5.27518 (rank : 207)	NC score	0.024967 (rank : 247)
Query Neighborhood Hits	295	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

CK051_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.030474 (rank : 221)
Query Neighborhood Hits	295	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60006, Q9CXK2, Q9Y269	Gene names	C11orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51.

CK051_MOUSE
θ value	5.27518 (rank : 209)	NC score	0.029840 (rank : 228)
Query Neighborhood Hits	295	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60007, Q3UXV5, Q9CXK2, Q9Y269	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51 homolog.

DDX55_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.377844 (rank : 73)
Query Neighborhood Hits	295	Target Neighborhood Hits	111	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

EPAS1_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.005263 (rank : 310)
Query Neighborhood Hits	295	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EVI1_HUMAN
θ value	5.27518 (rank : 212)	NC score	-0.004497 (rank : 322)
Query Neighborhood Hits	295	Target Neighborhood Hits	924	Shared Neighborhood Hits	23
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

KI21A_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.024566 (rank : 251)
Query Neighborhood Hits	295	Target Neighborhood Hits	1317	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LEO1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.069414 (rank : 99)
Query Neighborhood Hits	295	Target Neighborhood Hits	946	Shared Neighborhood Hits	112
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MINT_MOUSE
θ value	5.27518 (rank : 215)	NC score	0.029959 (rank : 227)
Query Neighborhood Hits	295	Target Neighborhood Hits	1514	Shared Neighborhood Hits	98
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYH1_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.041838 (rank : 182)
Query Neighborhood Hits	295	Target Neighborhood Hits	1478	Shared Neighborhood Hits	105
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

NUP54_MOUSE
θ value	5.27518 (rank : 217)	NC score	0.035487 (rank : 205)
Query Neighborhood Hits	295	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

PELP1_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.041242 (rank : 186)
Query Neighborhood Hits	295	Target Neighborhood Hits	596	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

REN3B_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.043178 (rank : 175)
Query Neighborhood Hits	295	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

SMYD3_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.008955 (rank : 298)
Query Neighborhood Hits	295	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TCF8_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.002262 (rank : 317)
Query Neighborhood Hits	295	Target Neighborhood Hits	1057	Shared Neighborhood Hits	61
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

UACA_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.037814 (rank : 194)
Query Neighborhood Hits	295	Target Neighborhood Hits	1622	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ZNFX1_MOUSE
θ value	5.27518 (rank : 223)	NC score	0.013735 (rank : 287)
Query Neighborhood Hits	295	Target Neighborhood Hits	407	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AN30A_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.035715 (rank : 203)
Query Neighborhood Hits	295	Target Neighborhood Hits	1119	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANC2_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.010087 (rank : 292)
Query Neighborhood Hits	295	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANR52_HUMAN
θ value	6.88961 (rank : 226)	NC score	0.004253 (rank : 315)
Query Neighborhood Hits	295	Target Neighborhood Hits	322	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.004278 (rank : 314)
Query Neighborhood Hits	295	Target Neighborhood Hits	318	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ATRX_HUMAN
θ value	6.88961 (rank : 228)	NC score	0.040623 (rank : 188)
Query Neighborhood Hits	295	Target Neighborhood Hits	842	Shared Neighborhood Hits	115
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BACH2_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.001552 (rank : 320)
Query Neighborhood Hits	295	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

CHD9_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.018015 (rank : 271)
Query Neighborhood Hits	295	Target Neighborhood Hits	343	Shared Neighborhood Hits	43
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CL025_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.024846 (rank : 249)
Query Neighborhood Hits	295	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

CTRO_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.027706 (rank : 237)
Query Neighborhood Hits	295	Target Neighborhood Hits	2344	Shared Neighborhood Hits	129
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DICER_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.190066 (rank : 82)
Query Neighborhood Hits	295	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

FA50A_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.028872 (rank : 233)
Query Neighborhood Hits	295	Target Neighborhood Hits	264	Shared Neighborhood Hits	43
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

FANCM_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.202054 (rank : 80)
Query Neighborhood Hits	295	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

K1C14_HUMAN
θ value	6.88961 (rank : 236)	NC score	0.016232 (rank : 275)
Query Neighborhood Hits	295	Target Neighborhood Hits	491	Shared Neighborhood Hits	64
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

KIF1A_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.007825 (rank : 306)
Query Neighborhood Hits	295	Target Neighborhood Hits	240	Shared Neighborhood Hits	36
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_MOUSE
θ value	6.88961 (rank : 238)	NC score	0.007710 (rank : 307)
Query Neighborhood Hits	295	Target Neighborhood Hits	239	Shared Neighborhood Hits	35
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

LEO1_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.066846 (rank : 100)
Query Neighborhood Hits	295	Target Neighborhood Hits	958	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAP1B_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.031571 (rank : 218)
Query Neighborhood Hits	295	Target Neighborhood Hits	903	Shared Neighborhood Hits	86
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYH1_MOUSE
θ value	6.88961 (rank : 241)	NC score	0.041523 (rank : 184)
Query Neighborhood Hits	295	Target Neighborhood Hits	1461	Shared Neighborhood Hits	102
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH7_HUMAN
θ value	6.88961 (rank : 242)	NC score	0.042722 (rank : 178)
Query Neighborhood Hits	295	Target Neighborhood Hits	1559	Shared Neighborhood Hits	113
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NC6IP_HUMAN
θ value	6.88961 (rank : 243)	NC score	0.022770 (rank : 256)
Query Neighborhood Hits	295	Target Neighborhood Hits	116	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

PARP1_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.008555 (rank : 302)
Query Neighborhood Hits	295	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PCDA4_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.018931 (rank : 267)
Query Neighborhood Hits	295	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PHF2_HUMAN
θ value	6.88961 (rank : 246)	NC score	0.004590 (rank : 312)
Query Neighborhood Hits	295	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

RBM19_MOUSE
θ value	6.88961 (rank : 247)	NC score	0.008580 (rank : 301)
Query Neighborhood Hits	295	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

SK2L2_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.078633 (rank : 95)
Query Neighborhood Hits	295	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.077588 (rank : 96)
Query Neighborhood Hits	295	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SKI_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.032053 (rank : 217)
Query Neighborhood Hits	295	Target Neighborhood Hits	423	Shared Neighborhood Hits	58
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

SMRCD_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.021344 (rank : 258)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SPRL1_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.028257 (rank : 234)
Query Neighborhood Hits	295	Target Neighborhood Hits	403	Shared Neighborhood Hits	59
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SPTN2_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.016589 (rank : 274)
Query Neighborhood Hits	295	Target Neighborhood Hits	535	Shared Neighborhood Hits	63
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SRCH_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.028231 (rank : 235)
Query Neighborhood Hits	295	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TACT_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.014445 (rank : 283)
Query Neighborhood Hits	295	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

TAF7_HUMAN
θ value	6.88961 (rank : 256)	NC score	0.032808 (rank : 213)
Query Neighborhood Hits	295	Target Neighborhood Hits	222	Shared Neighborhood Hits	48
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TUR8_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.052183 (rank : 136)
Query Neighborhood Hits	295	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

YTDC1_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.035770 (rank : 202)
Query Neighborhood Hits	295	Target Neighborhood Hits	458	Shared Neighborhood Hits	65
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZMYM3_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.008547 (rank : 303)
Query Neighborhood Hits	295	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ACINU_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.034157 (rank : 209)
Query Neighborhood Hits	295	Target Neighborhood Hits	828	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AN32E_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.020712 (rank : 261)
Query Neighborhood Hits	295	Target Neighborhood Hits	291	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

ARI4A_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.038413 (rank : 193)
Query Neighborhood Hits	295	Target Neighborhood Hits	434	Shared Neighborhood Hits	59
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

AT11B_HUMAN
θ value	8.99809 (rank : 263)	NC score	0.001686 (rank : 319)
Query Neighborhood Hits	295	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G3, Q96FN1, Q9UKK7	Gene names	ATP11B, ATPIF, ATPIR, KIAA0956
Domain Architecture
Description	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase class I type 11B) (ATPase IR).

BIG2_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.004474 (rank : 313)
Query Neighborhood Hits	295	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BTBDC_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.030548 (rank : 220)
Query Neighborhood Hits	295	Target Neighborhood Hits	248	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CD2L1_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.008969 (rank : 297)
Query Neighborhood Hits	295	Target Neighborhood Hits	1463	Shared Neighborhood Hits	99
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CLSPN_MOUSE
θ value	8.99809 (rank : 267)	NC score	0.029818 (rank : 229)
Query Neighborhood Hits	295	Target Neighborhood Hits	292	Shared Neighborhood Hits	45
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

CNOT4_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.012199 (rank : 288)
Query Neighborhood Hits	295	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.011661 (rank : 289)
Query Neighborhood Hits	295	Target Neighborhood Hits	277	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

COMD8_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.011301 (rank : 290)
Query Neighborhood Hits	295	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZG3, Q9D7F6	Gene names	Commd8
Domain Architecture	No domain graphic available
Description	COMM domain-containing protein 8.

CROCC_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.043667 (rank : 170)
Query Neighborhood Hits	295	Target Neighborhood Hits	1409	Shared Neighborhood Hits	105
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CUTL2_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.027539 (rank : 239)
Query Neighborhood Hits	295	Target Neighborhood Hits	906	Shared Neighborhood Hits	73
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DICER_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.187281 (rank : 83)
Query Neighborhood Hits	295	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

EI2BB_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.008399 (rank : 304)
Query Neighborhood Hits	295	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P49770, O43201	Gene names	EIF2B2, EIF2BB
Domain Architecture
Description	Translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta) (S20I15) (S20III15).

IFIH1_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.172598 (rank : 85)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LIPA1_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.046784 (rank : 161)
Query Neighborhood Hits	295	Target Neighborhood Hits	1294	Shared Neighborhood Hits	116
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MACF1_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.036094 (rank : 200)
Query Neighborhood Hits	295	Target Neighborhood Hits	1341	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.040099 (rank : 190)
Query Neighborhood Hits	295	Target Neighborhood Hits	1321	Shared Neighborhood Hits	95
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MASTL_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.002096 (rank : 318)
Query Neighborhood Hits	295	Target Neighborhood Hits	862	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MD1L1_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.044533 (rank : 167)
Query Neighborhood Hits	295	Target Neighborhood Hits	893	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MIER1_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.010026 (rank : 293)
Query Neighborhood Hits	295	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

MLL3_MOUSE
θ value	8.99809 (rank : 282)	NC score	0.020740 (rank : 260)
Query Neighborhood Hits	295	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYH3_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.043231 (rank : 174)
Query Neighborhood Hits	295	Target Neighborhood Hits	1660	Shared Neighborhood Hits	120
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NIN_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.046466 (rank : 164)
Query Neighborhood Hits	295	Target Neighborhood Hits	1416	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NOL6_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.008719 (rank : 300)
Query Neighborhood Hits	295	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H6R4, Q5T5M3, Q5T5M4, Q7L4G6, Q8N6I0, Q8TEY9, Q8TEZ0, Q8TEZ1, Q9H675	Gene names	NOL6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

NOP14_MOUSE
θ value	8.99809 (rank : 286)	NC score	0.029996 (rank : 226)
Query Neighborhood Hits	295	Target Neighborhood Hits	324	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

OSTP_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.014935 (rank : 280)
Query Neighborhood Hits	295	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

PININ_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.059753 (rank : 105)
Query Neighborhood Hits	295	Target Neighborhood Hits	777	Shared Neighborhood Hits	104
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PLCB3_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.015518 (rank : 278)
Query Neighborhood Hits	295	Target Neighborhood Hits	344	Shared Neighborhood Hits	46
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

ROCK1_MOUSE
θ value	8.99809 (rank : 290)	NC score	0.025863 (rank : 242)
Query Neighborhood Hits	295	Target Neighborhood Hits	2126	Shared Neighborhood Hits	114
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SETX_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.018076 (rank : 270)
Query Neighborhood Hits	295	Target Neighborhood Hits	368	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SYNE2_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.041424 (rank : 185)
Query Neighborhood Hits	295	Target Neighborhood Hits	1323	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TEX2_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.008790 (rank : 299)
Query Neighborhood Hits	295	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TLR3_HUMAN
θ value	8.99809 (rank : 294)	NC score	-0.001501 (rank : 321)
Query Neighborhood Hits	295	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TNR21_MOUSE
θ value	8.99809 (rank : 295)	NC score	0.004785 (rank : 311)
Query Neighborhood Hits	295	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CALD1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.052026 (rank : 138)
Query Neighborhood Hits	295	Target Neighborhood Hits	959	Shared Neighborhood Hits	95
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CC026_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.075351 (rank : 97)
Query Neighborhood Hits	295	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.054387 (rank : 123)
Query Neighborhood Hits	295	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CI039_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.053290 (rank : 130)
Query Neighborhood Hits	295	Target Neighborhood Hits	1171	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.050223 (rank : 152)
Query Neighborhood Hits	295	Target Neighborhood Hits	1088	Shared Neighborhood Hits	99
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CK5P2_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.051237 (rank : 146)
Query Neighborhood Hits	295	Target Neighborhood Hits	1151	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

DDX10_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.405932 (rank : 66)
Query Neighborhood Hits	295	Target Neighborhood Hits	210	Shared Neighborhood Hits	104
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.402004 (rank : 69)
Query Neighborhood Hits	295	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.385639 (rank : 72)
Query Neighborhood Hits	295	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX18_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.376665 (rank : 74)
Query Neighborhood Hits	295	Target Neighborhood Hits	115	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX47_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.431870 (rank : 52)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.431736 (rank : 53)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX55_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.373745 (rank : 75)
Query Neighborhood Hits	295	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.363536 (rank : 77)
Query Neighborhood Hits	295	Target Neighborhood Hits	77	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.364854 (rank : 76)
Query Neighborhood Hits	295	Target Neighborhood Hits	87	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX58_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.079847 (rank : 94)
Query Neighborhood Hits	295	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.090713 (rank : 91)
Query Neighborhood Hits	295	Target Neighborhood Hits	99	Shared Neighborhood Hits	52
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

LGP2_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.165926 (rank : 89)
Query Neighborhood Hits	295	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.169547 (rank : 87)
Query Neighborhood Hits	295	Target Neighborhood Hits	86	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

MY18A_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.050190 (rank : 153)
Query Neighborhood Hits	295	Target Neighborhood Hits	1989	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NASP_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.053510 (rank : 128)
Query Neighborhood Hits	295	Target Neighborhood Hits	709	Shared Neighborhood Hits	102
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NOP14_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.052847 (rank : 134)
Query Neighborhood Hits	295	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NSBP1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.052021 (rank : 139)
Query Neighborhood Hits	295	Target Neighborhood Hits	681	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RAD50_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.051545 (rank : 144)
Query Neighborhood Hits	295	Target Neighborhood Hits	1366	Shared Neighborhood Hits	117
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RRBP1_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.051906 (rank : 142)
Query Neighborhood Hits	295	Target Neighborhood Hits	1650	Shared Neighborhood Hits	128
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SMC2_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.051923 (rank : 141)
Query Neighborhood Hits	295	Target Neighborhood Hits	1405	Shared Neighborhood Hits	117
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TXND2_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.051734 (rank : 143)
Query Neighborhood Hits	295	Target Neighborhood Hits	828	Shared Neighborhood Hits	95
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

WRN_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	295	Target Neighborhood Hits	295	Shared Neighborhood Hits	295
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

WRN_HUMAN
NC score	0.960445 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	295	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.855730 (rank : 3)	θ value	3.03575e-64 (rank : 3)
Query Neighborhood Hits	295	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.850749 (rank : 4)	θ value	8.83269e-64 (rank : 4)
Query Neighborhood Hits	295	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_MOUSE
NC score	0.820477 (rank : 5)	θ value	2.7521e-57 (rank : 6)
Query Neighborhood Hits	295	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.814468 (rank : 6)	θ value	2.18062e-54 (rank : 7)
Query Neighborhood Hits	295	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.811795 (rank : 7)	θ value	6.55044e-59 (rank : 5)
Query Neighborhood Hits	295	Target Neighborhood Hits	390	Shared Neighborhood Hits	87
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ4_HUMAN
NC score	0.788967 (rank : 8)	θ value	7.27602e-42 (rank : 8)
Query Neighborhood Hits	295	Target Neighborhood Hits	177	Shared Neighborhood Hits	82
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.783924 (rank : 9)	θ value	4.88048e-38 (rank : 9)
Query Neighborhood Hits	295	Target Neighborhood Hits	206	Shared Neighborhood Hits	84
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX46_MOUSE
NC score	0.497752 (rank : 10)	θ value	1.133e-10 (rank : 10)
Query Neighborhood Hits	295	Target Neighborhood Hits	358	Shared Neighborhood Hits	124
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX46_HUMAN
NC score	0.497361 (rank : 11)	θ value	5.62301e-10 (rank : 11)
Query Neighborhood Hits	295	Target Neighborhood Hits	357	Shared Neighborhood Hits	125
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX17_MOUSE
NC score	0.493633 (rank : 12)	θ value	2.61198e-07 (rank : 25)
Query Neighborhood Hits	295	Target Neighborhood Hits	105	Shared Neighborhood Hits	74
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.493596 (rank : 13)	θ value	2.61198e-07 (rank : 24)
Query Neighborhood Hits	295	Target Neighborhood Hits	104	Shared Neighborhood Hits	75
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX5_MOUSE
NC score	0.489393 (rank : 14)	θ value	1.09739e-05 (rank : 33)
Query Neighborhood Hits	295	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.489006 (rank : 15)	θ value	1.09739e-05 (rank : 32)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX43_HUMAN
NC score	0.483834 (rank : 16)	θ value	9.92553e-07 (rank : 29)
Query Neighborhood Hits	295	Target Neighborhood Hits	120	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX41_HUMAN
NC score	0.478508 (rank : 17)	θ value	5.26297e-08 (rank : 16)
Query Neighborhood Hits	295	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX3X_MOUSE
NC score	0.477095 (rank : 18)	θ value	5.26297e-08 (rank : 15)
Query Neighborhood Hits	295	Target Neighborhood Hits	117	Shared Neighborhood Hits	78
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX41_MOUSE
NC score	0.476905 (rank : 19)	θ value	5.26297e-08 (rank : 17)
Query Neighborhood Hits	295	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX3X_HUMAN
NC score	0.475462 (rank : 20)	θ value	6.87365e-08 (rank : 19)
Query Neighborhood Hits	295	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX6_HUMAN
NC score	0.475323 (rank : 21)	θ value	1.17247e-07 (rank : 21)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.475231 (rank : 22)	θ value	1.17247e-07 (rank : 22)
Query Neighborhood Hits	295	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX52_MOUSE
NC score	0.474867 (rank : 23)	θ value	7.59969e-07 (rank : 28)
Query Neighborhood Hits	295	Target Neighborhood Hits	101	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
NC score	0.474486 (rank : 24)	θ value	1.69304e-06 (rank : 30)
Query Neighborhood Hits	295	Target Neighborhood Hits	107	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX3Y_HUMAN
NC score	0.474320 (rank : 25)	θ value	1.17247e-07 (rank : 20)
Query Neighborhood Hits	295	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

PL10_MOUSE
NC score	0.473397 (rank : 26)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	295	Target Neighborhood Hits	120	Shared Neighborhood Hits	76
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_MOUSE
NC score	0.472601 (rank : 27)	θ value	6.21693e-09 (rank : 12)
Query Neighborhood Hits	295	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX50_HUMAN
NC score	0.470366 (rank : 28)	θ value	1.87187e-05 (rank : 34)
Query Neighborhood Hits	295	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX23_HUMAN
NC score	0.470330 (rank : 29)	θ value	8.40245e-06 (rank : 31)
Query Neighborhood Hits	295	Target Neighborhood Hits	486	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX50_MOUSE
NC score	0.469966 (rank : 30)	θ value	1.87187e-05 (rank : 35)
Query Neighborhood Hits	295	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX48_HUMAN
NC score	0.465199 (rank : 31)	θ value	2.61198e-07 (rank : 26)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.464999 (rank : 32)	θ value	2.61198e-07 (rank : 27)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX21_HUMAN
NC score	0.462895 (rank : 33)	θ value	0.000121331 (rank : 36)
Query Neighborhood Hits	295	Target Neighborhood Hits	308	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX53_HUMAN
NC score	0.456264 (rank : 34)	θ value	8.11959e-09 (rank : 13)
Query Neighborhood Hits	295	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX21_MOUSE
NC score	0.454308 (rank : 35)	θ value	0.00102713 (rank : 51)
Query Neighborhood Hits	295	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX49_MOUSE
NC score	0.452166 (rank : 36)	θ value	0.00020696 (rank : 41)
Query Neighborhood Hits	295	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

IF4A2_HUMAN
NC score	0.450557 (rank : 37)	θ value	0.00020696 (rank : 42)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.450557 (rank : 38)	θ value	0.00020696 (rank : 43)
Query Neighborhood Hits	295	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
NC score	0.449787 (rank : 39)	θ value	0.000158464 (rank : 39)
Query Neighborhood Hits	295	Target Neighborhood Hits	106	Shared Neighborhood Hits	75
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.449787 (rank : 40)	θ value	0.000158464 (rank : 40)
Query Neighborhood Hits	295	Target Neighborhood Hits	106	Shared Neighborhood Hits	75
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX49_HUMAN
NC score	0.448355 (rank : 41)	θ value	0.00390308 (rank : 58)
Query Neighborhood Hits	295	Target Neighborhood Hits	223	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
NC score	0.446614 (rank : 42)	θ value	0.000121331 (rank : 37)
Query Neighborhood Hits	295	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.445662 (rank : 43)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	295	Target Neighborhood Hits	197	Shared Neighborhood Hits	95
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX4_HUMAN
NC score	0.444464 (rank : 44)	θ value	0.00509761 (rank : 59)
Query Neighborhood Hits	295	Target Neighborhood Hits	123	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
NC score	0.443767 (rank : 45)	θ value	0.00509761 (rank : 60)
Query Neighborhood Hits	295	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX39_HUMAN
NC score	0.442971 (rank : 46)	θ value	0.00035302 (rank : 44)
Query Neighborhood Hits	295	Target Neighborhood Hits	94	Shared Neighborhood Hits	76
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
NC score	0.441013 (rank : 47)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX54_MOUSE
NC score	0.438735 (rank : 48)	θ value	0.000602161 (rank : 46)
Query Neighborhood Hits	295	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
NC score	0.435904 (rank : 49)	θ value	0.000602161 (rank : 45)
Query Neighborhood Hits	295	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

UAP56_HUMAN
NC score	0.433664 (rank : 50)	θ value	0.00298849 (rank : 56)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.433517 (rank : 51)	θ value	0.00298849 (rank : 57)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX47_HUMAN
NC score	0.431870 (rank : 52)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
NC score	0.431736 (rank : 53)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	295	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX24_MOUSE
NC score	0.431007 (rank : 54)	θ value	0.00134147 (rank : 53)
Query Neighborhood Hits	295	Target Neighborhood Hits	147	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
NC score	0.429309 (rank : 55)	θ value	0.00102713 (rank : 52)
Query Neighborhood Hits	295	Target Neighborhood Hits	190	Shared Neighborhood Hits	88
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX1_MOUSE
NC score	0.424680 (rank : 56)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	295	Target Neighborhood Hits	112	Shared Neighborhood Hits	74
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX31_HUMAN
NC score	0.422004 (rank : 57)	θ value	0.00134147 (rank : 54)
Query Neighborhood Hits	295	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX1_HUMAN
NC score	0.421768 (rank : 58)	θ value	0.00665767 (rank : 61)
Query Neighborhood Hits	295	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX51_MOUSE
NC score	0.414092 (rank : 59)	θ value	0.00228821 (rank : 55)
Query Neighborhood Hits	295	Target Neighborhood Hits	130	Shared Neighborhood Hits	78
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX28_MOUSE
NC score	0.413004 (rank : 60)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	295	Target Neighborhood Hits	112	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_HUMAN
NC score	0.411891 (rank : 61)	θ value	0.0113563 (rank : 64)
Query Neighborhood Hits	295	Target Neighborhood Hits	332	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DD19A_HUMAN
NC score	0.408146 (rank : 62)	θ value	0.00102713 (rank : 48)
Query Neighborhood Hits	295	Target Neighborhood Hits	107	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.407651 (rank : 63)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	295	Target Neighborhood Hits	109	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.407472 (rank : 64)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	295	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX20_HUMAN
NC score	0.406839 (rank : 65)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	295	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX10_HUMAN
NC score	0.405932 (rank : 66)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	295	Target Neighborhood Hits	210	Shared Neighborhood Hits	104
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX20_MOUSE
NC score	0.404485 (rank : 67)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	295	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX25_HUMAN
NC score	0.403773 (rank : 68)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	295	Target Neighborhood Hits	93	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX10_MOUSE
NC score	0.402004 (rank : 69)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	295	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX25_MOUSE
NC score	0.401890 (rank : 70)	θ value	0.0148317 (rank : 66)
Query Neighborhood Hits	295	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX28_HUMAN
NC score	0.395828 (rank : 71)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	295	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX18_HUMAN
NC score	0.385639 (rank : 72)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	295	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX55_MOUSE
NC score	0.377844 (rank : 73)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	295	Target Neighborhood Hits	111	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX18_MOUSE
NC score	0.376665 (rank : 74)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	295	Target Neighborhood Hits	115	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX55_HUMAN
NC score	0.373745 (rank : 75)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	295	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
NC score	0.364854 (rank : 76)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	295	Target Neighborhood Hits	87	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.363536 (rank : 77)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	295	Target Neighborhood Hits	77	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

EXDL2_HUMAN
NC score	0.241808 (rank : 78)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	295	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
NC score	0.237441 (rank : 79)	θ value	1.53129e-07 (rank : 23)
Query Neighborhood Hits	295	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

FANCM_HUMAN
NC score	0.202054 (rank : 80)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	295	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.198269 (rank : 81)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	295	Target Neighborhood Hits	177	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_MOUSE
NC score	0.190066 (rank : 82)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	295	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.187281 (rank : 83)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	295	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

U520_HUMAN
NC score	0.175935 (rank : 84)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	295	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

IFIH1_HUMAN
NC score	0.172598 (rank : 85)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
NC score	0.172204 (rank : 86)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	295	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_MOUSE
NC score	0.169547 (rank : 87)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	295	Target Neighborhood Hits	86	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

HELC1_HUMAN
NC score	0.166426 (rank : 88)	θ value	0.00665767 (rank : 63)
Query Neighborhood Hits	295	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

LGP2_HUMAN
NC score	0.165926 (rank : 89)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	295	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

SKIV2_HUMAN
NC score	0.091737 (rank : 90)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	295	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

DDX58_MOUSE
NC score	0.090713 (rank : 91)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	295	Target Neighborhood Hits	99	Shared Neighborhood Hits	52
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

VDP_MOUSE
NC score	0.082304 (rank : 92)	θ value	0.0148317 (rank : 70)
Query Neighborhood Hits	295	Target Neighborhood Hits	469	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

DMP1_HUMAN
NC score	0.080850 (rank : 93)	θ value	0.0563607 (rank : 77)
Query Neighborhood Hits	295	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DDX58_HUMAN
NC score	0.079847 (rank : 94)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	295	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

SK2L2_HUMAN
NC score	0.078633 (rank : 95)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	295	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
NC score	0.077588 (rank : 96)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	295	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

CC026_HUMAN
NC score	0.075351 (rank : 97)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	295	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

VDP_HUMAN
NC score	0.073417 (rank : 98)	θ value	0.0961366 (rank : 82)
Query Neighborhood Hits	295	Target Neighborhood Hits	645	Shared Neighborhood Hits	73
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

LEO1_MOUSE
NC score	0.069414 (rank : 99)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	295	Target Neighborhood Hits	946	Shared Neighborhood Hits	112
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.066846 (rank : 100)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	295	Target Neighborhood Hits	958	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

GOGA4_HUMAN
NC score	0.064381 (rank : 101)	θ value	0.0113563 (rank : 65)
Query Neighborhood Hits	295	Target Neighborhood Hits	2034	Shared Neighborhood Hits	137
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KTN1_MOUSE
NC score	0.062172 (rank : 102)	θ value	0.0193708 (rank : 72)
Query Neighborhood Hits	295	Target Neighborhood Hits	1324	Shared Neighborhood Hits	110
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

GOGB1_HUMAN
NC score	0.061242 (rank : 103)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	295	Target Neighborhood Hits	2297	Shared Neighborhood Hits	142
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IF2P_HUMAN
NC score	0.060507 (rank : 104)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	295	Target Neighborhood Hits	889	Shared Neighborhood Hits	99
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PININ_MOUSE
NC score	0.059753 (rank : 105)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	295	Target Neighborhood Hits	777	Shared Neighborhood Hits	104
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

CT2NL_HUMAN
NC score	0.059699 (rank : 106)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	295	Target Neighborhood Hits	1059	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PININ_HUMAN
NC score	0.058241 (rank : 107)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	295	Target Neighborhood Hits	753	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

IWS1_MOUSE
NC score	0.057983 (rank : 108)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	295	Target Neighborhood Hits	1258	Shared Neighborhood Hits	106
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RB6I2_HUMAN
NC score	0.057886 (rank : 109)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	295	Target Neighborhood Hits	1584	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

PEPL_HUMAN
NC score	0.057815 (rank : 110)	θ value	0.0961366 (rank : 80)
Query Neighborhood Hits	295	Target Neighborhood Hits	1141	Shared Neighborhood Hits	105
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

ZW10_MOUSE
NC score	0.056813 (rank : 111)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	295	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

PEPL_MOUSE
NC score	0.056480 (rank : 112)	θ value	0.813845 (rank : 125)
Query Neighborhood Hits	295	Target Neighborhood Hits	1105	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SMC1A_MOUSE
NC score	0.056460 (rank : 113)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	295	Target Neighborhood Hits	1384	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

IWS1_HUMAN
NC score	0.056448 (rank : 114)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	295	Target Neighborhood Hits	1241	Shared Neighborhood Hits	114
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ATX2_HUMAN
NC score	0.055969 (rank : 115)	θ value	0.0252991 (rank : 74)
Query Neighborhood Hits	295	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

RB6I2_MOUSE
NC score	0.055848 (rank : 116)	θ value	0.0961366 (rank : 81)
Query Neighborhood Hits	295	Target Neighborhood Hits	1433	Shared Neighborhood Hits	112
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CK5P2_HUMAN
NC score	0.055823 (rank : 117)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	295	Target Neighborhood Hits	1433	Shared Neighborhood Hits	125
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GOGA4_MOUSE
NC score	0.055787 (rank : 118)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	295	Target Neighborhood Hits	1939	Shared Neighborhood Hits	135
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

ATX2_MOUSE
NC score	0.055624 (rank : 119)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	295	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SMC1A_HUMAN
NC score	0.055620 (rank : 120)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	295	Target Neighborhood Hits	1346	Shared Neighborhood Hits	119
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

TRHY_HUMAN
NC score	0.054725 (rank : 121)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	295	Target Neighborhood Hits	1385	Shared Neighborhood Hits	104
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

RPGR1_MOUSE
NC score	0.054588 (rank : 122)	θ value	0.365318 (rank : 99)
Query Neighborhood Hits	295	Target Neighborhood Hits	713	Shared Neighborhood Hits	90
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CC026_MOUSE
NC score	0.054387 (rank : 123)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	295	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

HMMR_MOUSE
NC score	0.054312 (rank : 124)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	295	Target Neighborhood Hits	1178	Shared Neighborhood Hits	103
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GCC2_MOUSE
NC score	0.053926 (rank : 125)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	295	Target Neighborhood Hits	1619	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

SFPQ_HUMAN
NC score	0.053882 (rank : 126)	θ value	0.0148317 (rank : 69)
Query Neighborhood Hits	295	Target Neighborhood Hits	986	Shared Neighborhood Hits	73
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

KTN1_HUMAN
NC score	0.053850 (rank : 127)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	295	Target Neighborhood Hits	1197	Shared Neighborhood Hits	98
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

NASP_HUMAN
NC score	0.053510 (rank : 128)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	295	Target Neighborhood Hits	709	Shared Neighborhood Hits	102
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SFPQ_MOUSE
NC score	0.053325 (rank : 129)	θ value	0.0193708 (rank : 73)
Query Neighborhood Hits	295	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CI039_HUMAN
NC score	0.053290 (rank : 130)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	295	Target Neighborhood Hits	1171	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CP135_HUMAN
NC score	0.053075 (rank : 131)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	295	Target Neighborhood Hits	1290	Shared Neighborhood Hits	101
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOG8A_HUMAN
NC score	0.052993 (rank : 132)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	295	Target Neighborhood Hits	635	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

PCNT_HUMAN
NC score	0.052990 (rank : 133)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	295	Target Neighborhood Hits	1551	Shared Neighborhood Hits	110
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

NOP14_HUMAN
NC score	0.052847 (rank : 134)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	295	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PIBF1_HUMAN
NC score	0.052220 (rank : 135)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	295	Target Neighborhood Hits	1041	Shared Neighborhood Hits	100
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

TUR8_MOUSE
NC score	0.052183 (rank : 136)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	295	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

CEP35_HUMAN
NC score	0.052133 (rank : 137)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	295	Target Neighborhood Hits	811	Shared Neighborhood Hits	97
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CALD1_HUMAN
NC score	0.052026 (rank : 138)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	295	Target Neighborhood Hits	959	Shared Neighborhood Hits	95
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

NSBP1_MOUSE
NC score	0.052021 (rank : 139)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	295	Target Neighborhood Hits	681	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NIPBL_HUMAN
NC score	0.051985 (rank : 140)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	295	Target Neighborhood Hits	1311	Shared Neighborhood Hits	112
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SMC2_HUMAN
NC score	0.051923 (rank : 141)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	295	Target Neighborhood Hits	1405	Shared Neighborhood Hits	117
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

RRBP1_MOUSE
NC score	0.051906 (rank : 142)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	295	Target Neighborhood Hits	1650	Shared Neighborhood Hits	128
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TXND2_MOUSE
NC score	0.051734 (rank : 143)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	295	Target Neighborhood Hits	828	Shared Neighborhood Hits	95
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

RAD50_MOUSE
NC score	0.051545 (rank : 144)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	295	Target Neighborhood Hits	1366	Shared Neighborhood Hits	117
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CE290_HUMAN
NC score	0.051526 (rank : 145)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	295	Target Neighborhood Hits	1553	Shared Neighborhood Hits	111
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CK5P2_MOUSE
NC score	0.051237 (rank : 146)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	295	Target Neighborhood Hits	1151	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

MDN1_HUMAN
NC score	0.050773 (rank : 147)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	295	Target Neighborhood Hits	662	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

AKAP9_HUMAN
NC score	0.050651 (rank : 148)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	295	Target Neighborhood Hits	1710	Shared Neighborhood Hits	118
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CN145_HUMAN
NC score	0.050553 (rank : 149)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	295	Target Neighborhood Hits	1196	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CCD39_HUMAN
NC score	0.050294 (rank : 150)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	295	Target Neighborhood Hits	868	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

HIRP3_HUMAN
NC score	0.050288 (rank : 151)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	295	Target Neighborhood Hits	323	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

CI093_HUMAN
NC score	0.050223 (rank : 152)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	295	Target Neighborhood Hits	1088	Shared Neighborhood Hits	99
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

MY18A_MOUSE
NC score	0.050190 (rank : 153)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	295	Target Neighborhood Hits	1989	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYT1L_HUMAN
NC score	0.049546 (rank : 154)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	295	Target Neighborhood Hits	471	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

DMP1_MOUSE
NC score	0.048039 (rank : 155)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	295	Target Neighborhood Hits	498	Shared Neighborhood Hits	66
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

MYT1_HUMAN
NC score	0.047660 (rank : 156)	θ value	0.813845 (rank : 123)
Query Neighborhood Hits	295	Target Neighborhood Hits	475	Shared Neighborhood Hits	76
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NPBL_MOUSE
NC score	0.047504 (rank : 157)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	295	Target Neighborhood Hits	1041	Shared Neighborhood Hits	87
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CLSPN_HUMAN
NC score	0.047288 (rank : 158)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	295	Target Neighborhood Hits	433	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

SPT5H_HUMAN
NC score	0.047179 (rank : 159)	θ value	0.125558 (rank : 85)
Query Neighborhood Hits	295	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

LUZP1_HUMAN
NC score	0.046960 (rank : 160)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	295	Target Neighborhood Hits	739	Shared Neighborhood Hits	79
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LIPA1_HUMAN
NC score	0.046784 (rank : 161)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	295	Target Neighborhood Hits	1294	Shared Neighborhood Hits	116
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MATR3_MOUSE
NC score	0.046766 (rank : 162)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	295	Target Neighborhood Hits	321	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

GOGA6_HUMAN
NC score	0.046589 (rank : 163)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	295	Target Neighborhood Hits	1007	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NIN_HUMAN
NC score	0.046466 (rank : 164)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	295	Target Neighborhood Hits	1416	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

SMC2_MOUSE
NC score	0.046039 (rank : 165)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	295	Target Neighborhood Hits	1131	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MYH13_HUMAN
NC score	0.044714 (rank : 166)	θ value	0.0736092 (rank : 79)
Query Neighborhood Hits	295	Target Neighborhood Hits	1504	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MD1L1_HUMAN
NC score	0.044533 (rank : 167)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	295	Target Neighborhood Hits	893	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

ANR26_MOUSE
NC score	0.044235 (rank : 168)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	295	Target Neighborhood Hits	1554	Shared Neighborhood Hits	114
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

PELP1_MOUSE
NC score	0.044171 (rank : 169)	θ value	0.62314 (rank : 114)
Query Neighborhood Hits	295	Target Neighborhood Hits	709	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

CROCC_HUMAN
NC score	0.043667 (rank : 170)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	295	Target Neighborhood Hits	1409	Shared Neighborhood Hits	105
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SMRC2_MOUSE
NC score	0.043632 (rank : 171)	θ value	0.62314 (rank : 115)
Query Neighborhood Hits	295	Target Neighborhood Hits	487	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MYH8_HUMAN
NC score	0.043588 (rank : 172)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	295	Target Neighborhood Hits	1610	Shared Neighborhood Hits	118
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

C8AP2_MOUSE
NC score	0.043326 (rank : 173)	θ value	0.163984 (rank : 87)
Query Neighborhood Hits	295	Target Neighborhood Hits	405	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

MYH3_HUMAN
NC score	0.043231 (rank : 174)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	295	Target Neighborhood Hits	1660	Shared Neighborhood Hits	120
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

REN3B_HUMAN
NC score	0.043178 (rank : 175)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	295	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

MYH6_MOUSE
NC score	0.042769 (rank : 176)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	295	Target Neighborhood Hits	1501	Shared Neighborhood Hits	106
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_HUMAN
NC score	0.042740 (rank : 177)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	295	Target Neighborhood Hits	1426	Shared Neighborhood Hits	104
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
NC score	0.042722 (rank : 178)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	295	Target Neighborhood Hits	1559	Shared Neighborhood Hits	113
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MATR3_HUMAN
NC score	0.042666 (rank : 179)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	295	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MYT1L_MOUSE
NC score	0.042586 (rank : 180)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	295	Target Neighborhood Hits	461	Shared Neighborhood Hits	66
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

HTSF1_MOUSE
NC score	0.042412 (rank : 181)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	295	Target Neighborhood Hits	425	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MYH1_HUMAN
NC score	0.041838 (rank : 182)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	295	Target Neighborhood Hits	1478	Shared Neighborhood Hits	105
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
NC score	0.041816 (rank : 183)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	295	Target Neighborhood Hits	1491	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH1_MOUSE
NC score	0.041523 (rank : 184)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	295	Target Neighborhood Hits	1461	Shared Neighborhood Hits	102
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

SYNE2_HUMAN
NC score	0.041424 (rank : 185)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	295	Target Neighborhood Hits	1323	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

PELP1_HUMAN
NC score	0.041242 (rank : 186)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	295	Target Neighborhood Hits	596	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SMRC2_HUMAN
NC score	0.040990 (rank : 187)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	295	Target Neighborhood Hits	499	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ATRX_HUMAN
NC score	0.040623 (rank : 188)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	295	Target Neighborhood Hits	842	Shared Neighborhood Hits	115
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

SPT5H_MOUSE
NC score	0.040584 (rank : 189)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	295	Target Neighborhood Hits	437	Shared Neighborhood Hits	30
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

MACF4_HUMAN
NC score	0.040099 (rank : 190)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	295	Target Neighborhood Hits	1321	Shared Neighborhood Hits	95
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

PPIG_HUMAN
NC score	0.039825 (rank : 191)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	295	Target Neighborhood Hits	670	Shared Neighborhood Hits	91
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

MYT1_MOUSE
NC score	0.038562 (rank : 192)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	295	Target Neighborhood Hits	385	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

ARI4A_HUMAN
NC score	0.038413 (rank : 193)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	295	Target Neighborhood Hits	434	Shared Neighborhood Hits	59
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

UACA_HUMAN
NC score	0.037814 (rank : 194)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	295	Target Neighborhood Hits	1622	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MYST3_MOUSE
NC score	0.037010 (rank : 195)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	295	Target Neighborhood Hits	688	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RPTN_MOUSE
NC score	0.036966 (rank : 196)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	295	Target Neighborhood Hits	650	Shared Neighborhood Hits	82
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

AN32B_MOUSE
NC score	0.036657 (rank : 197)	θ value	0.163984 (rank : 86)
Query Neighborhood Hits	295	Target Neighborhood Hits	236	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

MYST4_HUMAN
NC score	0.036406 (rank : 198)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	295	Target Neighborhood Hits	671	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

FA50A_MOUSE
NC score	0.036153 (rank : 199)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	295	Target Neighborhood Hits	293	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

MACF1_HUMAN
NC score	0.036094 (rank : 200)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	295	Target Neighborhood Hits	1341	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

NUP54_HUMAN
NC score	0.036015 (rank : 201)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	295	Target Neighborhood Hits	93	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

YTDC1_HUMAN
NC score	0.035770 (rank : 202)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	295	Target Neighborhood Hits	458	Shared Neighborhood Hits	65
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

AN30A_HUMAN
NC score	0.035715 (rank : 203)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	295	Target Neighborhood Hits	1119	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

MYST3_HUMAN
NC score	0.035686 (rank : 204)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	295	Target Neighborhood Hits	772	Shared Neighborhood Hits	69
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NUP54_MOUSE
NC score	0.035487 (rank : 205)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	295	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

UBF1_MOUSE
NC score	0.035443 (rank : 206)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	295	Target Neighborhood Hits	419	Shared Neighborhood Hits	50
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

ENAH_HUMAN
NC score	0.035282 (rank : 207)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	295	Target Neighborhood Hits	784	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SAFB2_HUMAN
NC score	0.035118 (rank : 208)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	295	Target Neighborhood Hits	720	Shared Neighborhood Hits	81
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

ACINU_HUMAN
NC score	0.034157 (rank : 209)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	295	Target Neighborhood Hits	828	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

JHD2C_MOUSE
NC score	0.033259 (rank : 210)	θ value	0.0431538 (rank : 75)
Query Neighborhood Hits	295	Target Neighborhood Hits	297	Shared Neighborhood Hits	35
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

CBP_MOUSE
NC score	0.033146 (rank : 211)	θ value	0.163984 (rank : 88)
Query Neighborhood Hits	295	Target Neighborhood Hits	1051	Shared Neighborhood Hits	53
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ESPL1_MOUSE
NC score	0.032912 (rank : 212)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	295	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

TAF7_HUMAN
NC score	0.032808 (rank : 213)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	295	Target Neighborhood Hits	222	Shared Neighborhood Hits	48
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

CDT1_MOUSE
NC score	0.032738 (rank : 214)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	295	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

SKI_HUMAN
NC score	0.032673 (rank : 215)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	295	Target Neighborhood Hits	423	Shared Neighborhood Hits	60
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

TRI44_MOUSE
NC score	0.032193 (rank : 216)	θ value	0.62314 (rank : 116)
Query Neighborhood Hits	295	Target Neighborhood Hits	327	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

SKI_MOUSE
NC score	0.032053 (rank : 217)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	295	Target Neighborhood Hits	423	Shared Neighborhood Hits	58
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

MAP1B_HUMAN
NC score	0.031571 (rank : 218)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	295	Target Neighborhood Hits	903	Shared Neighborhood Hits	86
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RYR1_HUMAN
NC score	0.030765 (rank : 219)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	295	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

BTBDC_HUMAN
NC score	0.030548 (rank : 220)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	295	Target Neighborhood Hits	248	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CK051_HUMAN
NC score	0.030474 (rank : 221)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	295	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60006, Q9CXK2, Q9Y269	Gene names	C11orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51.

CBP_HUMAN
NC score	0.030361 (rank : 222)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	295	Target Neighborhood Hits	941	Shared Neighborhood Hits	44
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MRCKB_HUMAN
NC score	0.030332 (rank : 223)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	295	Target Neighborhood Hits	2239	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TRI44_HUMAN
NC score	0.030315 (rank : 224)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	295	Target Neighborhood Hits	393	Shared Neighborhood Hits	44
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

MRCKB_MOUSE
NC score	0.030093 (rank : 225)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	295	Target Neighborhood Hits	2180	Shared Neighborhood Hits	115
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NOP14_MOUSE
NC score	0.029996 (rank : 226)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	295	Target Neighborhood Hits	324	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

MINT_MOUSE
NC score	0.029959 (rank : 227)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	295	Target Neighborhood Hits	1514	Shared Neighborhood Hits	98
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CK051_MOUSE
NC score	0.029840 (rank : 228)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	295	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60007, Q3UXV5, Q9CXK2, Q9Y269	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51 homolog.

CLSPN_MOUSE
NC score	0.029818 (rank : 229)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	295	Target Neighborhood Hits	292	Shared Neighborhood Hits	45
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

MYO6_HUMAN
NC score	0.029049 (rank : 230)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	295	Target Neighborhood Hits	727	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

ITSN1_HUMAN
NC score	0.028960 (rank : 231)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	295	Target Neighborhood Hits	1757	Shared Neighborhood Hits	120
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

EDD1_HUMAN
NC score	0.028942 (rank : 232)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	295	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

FA50A_HUMAN
NC score	0.028872 (rank : 233)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	295	Target Neighborhood Hits	264	Shared Neighborhood Hits	43
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

SPRL1_MOUSE
NC score	0.028257 (rank : 234)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	295	Target Neighborhood Hits	403	Shared Neighborhood Hits	59
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SRCH_HUMAN
NC score	0.028231 (rank : 235)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	295	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

SMRCD_HUMAN
NC score	0.027950 (rank : 236)	θ value	0.0431538 (rank : 76)
Query Neighborhood Hits	295	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CTRO_MOUSE
NC score	0.027706 (rank : 237)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	295	Target Neighborhood Hits	2344	Shared Neighborhood Hits	129
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ESPL1_HUMAN
NC score	0.027700 (rank : 238)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	295	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

CUTL2_HUMAN
NC score	0.027539 (rank : 239)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	295	Target Neighborhood Hits	906	Shared Neighborhood Hits	73
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

SETD2_HUMAN
NC score	0.026815 (rank : 240)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	295	Target Neighborhood Hits	412	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EDD1_MOUSE
NC score	0.026801 (rank : 241)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	295	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

ROCK1_MOUSE
NC score	0.025863 (rank : 242)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	295	Target Neighborhood Hits	2126	Shared Neighborhood Hits	114
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

CHD1_HUMAN
NC score	0.025541 (rank : 243)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	295	Target Neighborhood Hits	337	Shared Neighborhood Hits	49
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

BMS1_HUMAN
NC score	0.025312 (rank : 244)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	295	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

MRCKA_HUMAN
NC score	0.025062 (rank : 245)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	295	Target Neighborhood Hits	1999	Shared Neighborhood Hits	99
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

AN32A_MOUSE
NC score	0.024967 (rank : 246)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	295	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.024967 (rank : 247)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	295	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

ZCHC6_HUMAN
NC score	0.024874 (rank : 248)	θ value	0.813845 (rank : 128)
Query Neighborhood Hits	295	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

CL025_HUMAN
NC score	0.024846 (rank : 249)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	295	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

CTRO_HUMAN
NC score	0.024745 (rank : 250)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	295	Target Neighborhood Hits	2092	Shared Neighborhood Hits	107
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

KI21A_MOUSE
NC score	0.024566 (rank : 251)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	295	Target Neighborhood Hits	1317	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

EXO1_HUMAN
NC score	0.023482 (rank : 252)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	295	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

PCDA8_HUMAN
NC score	0.023425 (rank : 253)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	295	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

ROCK1_HUMAN
NC score	0.023318 (rank : 254)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	295	Target Neighborhood Hits	2000	Shared Neighborhood Hits	106
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

PCDAB_HUMAN
NC score	0.023316 (rank : 255)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	295	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

NC6IP_HUMAN
NC score	0.022770 (rank : 256)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	295	Target Neighborhood Hits	116	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

DHX16_HUMAN
NC score	0.021785 (rank : 257)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	295	Target Neighborhood Hits	356	Shared Neighborhood Hits	57
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

SMRCD_MOUSE
NC score	0.021344 (rank : 258)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

UBP8_HUMAN
NC score	0.020982 (rank : 259)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	295	Target Neighborhood Hits	751	Shared Neighborhood Hits	86
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

MLL3_MOUSE
NC score	0.020740 (rank : 260)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	295	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

AN32E_HUMAN
NC score	0.020712 (rank : 261)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	295	Target Neighborhood Hits	291	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

PCDA3_HUMAN
NC score	0.020416 (rank : 262)	θ value	0.813845 (rank : 124)
Query Neighborhood Hits	295	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

PCDA6_HUMAN
NC score	0.020383 (rank : 263)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	295	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

PCDA1_HUMAN
NC score	0.020206 (rank : 264)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	295	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

PCDAC_HUMAN
NC score	0.020043 (rank : 265)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	295	Target Neighborhood Hits	200	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN75, O75278	Gene names	PCDHA12
Domain Architecture
Description	Protocadherin alpha 12 precursor (PCDH-alpha12).

PCDAD_HUMAN
NC score	0.019909 (rank : 266)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	295	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

PCDA4_HUMAN
NC score	0.018931 (rank : 267)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	295	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

K1C14_MOUSE
NC score	0.018363 (rank : 268)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	295	Target Neighborhood Hits	501	Shared Neighborhood Hits	66
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

DIAP2_HUMAN
NC score	0.018229 (rank : 269)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	295	Target Neighborhood Hits	342	Shared Neighborhood Hits	45
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

SETX_HUMAN
NC score	0.018076 (rank : 270)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	295	Target Neighborhood Hits	368	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

CHD9_HUMAN
NC score	0.018015 (rank : 271)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	295	Target Neighborhood Hits	343	Shared Neighborhood Hits	43
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

G7C_HUMAN
NC score	0.017991 (rank : 272)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	295	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

SLK_MOUSE
NC score	0.017002 (rank : 273)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	295	Target Neighborhood Hits	1798	Shared Neighborhood Hits	116
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SPTN2_HUMAN
NC score	0.016589 (rank : 274)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	295	Target Neighborhood Hits	535	Shared Neighborhood Hits	63
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

K1C14_HUMAN
NC score	0.016232 (rank : 275)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	295	Target Neighborhood Hits	491	Shared Neighborhood Hits	64
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

SLK_HUMAN
NC score	0.016128 (rank : 276)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	295	Target Neighborhood Hits	1775	Shared Neighborhood Hits	108
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ATBF1_MOUSE
NC score	0.015877 (rank : 277)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	295	Target Neighborhood Hits	1841	Shared Neighborhood Hits	63
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PLCB3_MOUSE
NC score	0.015518 (rank : 278)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	295	Target Neighborhood Hits	344	Shared Neighborhood Hits	46
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

K0423_MOUSE
NC score	0.015118 (rank : 279)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	295	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

OSTP_HUMAN
NC score	0.014935 (rank : 280)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	295	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

TOM1_MOUSE
NC score	0.014711 (rank : 281)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	295	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

KCAB1_HUMAN
NC score	0.014450 (rank : 282)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	295	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q14722, Q13031, Q13302, Q16547, Q99869	Gene names	KCNAB1, KCNA1B
Domain Architecture
Description	Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1) (Kv-beta-1).

TACT_HUMAN
NC score	0.014445 (rank : 283)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	295	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

AIM1_HUMAN
NC score	0.014398 (rank : 284)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	295	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

FNBP2_HUMAN
NC score	0.014046 (rank : 285)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	295	Target Neighborhood Hits	432	Shared Neighborhood Hits	37
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

ATBF1_HUMAN
NC score	0.014002 (rank : 286)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	295	Target Neighborhood Hits	1547	Shared Neighborhood Hits	34
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ZNFX1_MOUSE
NC score	0.013735 (rank : 287)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	295	Target Neighborhood Hits	407	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CNOT4_HUMAN
NC score	0.012199 (rank : 288)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	295	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
NC score	0.011661 (rank : 289)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	295	Target Neighborhood Hits	277	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

COMD8_MOUSE
NC score	0.011301 (rank : 290)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	295	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZG3, Q9D7F6	Gene names	Commd8
Domain Architecture	No domain graphic available
Description	COMM domain-containing protein 8.

JADE1_MOUSE
NC score	0.010424 (rank : 291)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	295	Target Neighborhood Hits	160	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

ANC2_HUMAN
NC score	0.010087 (rank : 292)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	295	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

MIER1_MOUSE
NC score	0.010026 (rank : 293)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	295	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

APBB2_HUMAN
NC score	0.009976 (rank : 294)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	295	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

JHD3C_HUMAN
NC score	0.009485 (rank : 295)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	295	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

CD2L1_HUMAN
NC score	0.009259 (rank : 296)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	295	Target Neighborhood Hits	1467	Shared Neighborhood Hits	96
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L1_MOUSE
NC score	0.008969 (rank : 297)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	295	Target Neighborhood Hits	1463	Shared Neighborhood Hits	99
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

SMYD3_HUMAN
NC score	0.008955 (rank : 298)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	295	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TEX2_HUMAN
NC score	0.008790 (rank : 299)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	295	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

NOL6_HUMAN
NC score	0.008719 (rank : 300)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	295	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H6R4, Q5T5M3, Q5T5M4, Q7L4G6, Q8N6I0, Q8TEY9, Q8TEZ0, Q8TEZ1, Q9H675	Gene names	NOL6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

RBM19_MOUSE
NC score	0.008580 (rank : 301)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	295	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

PARP1_HUMAN
NC score	0.008555 (rank : 302)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	295	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

ZMYM3_HUMAN
NC score	0.008547 (rank : 303)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	295	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

EI2BB_HUMAN
NC score	0.008399 (rank : 304)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	295	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P49770, O43201	Gene names	EIF2B2, EIF2BB
Domain Architecture
Description	Translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta) (S20I15) (S20III15).

CNGA3_HUMAN
NC score	0.007949 (rank : 305)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	295	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

KIF1A_HUMAN
NC score	0.007825 (rank : 306)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	295	Target Neighborhood Hits	240	Shared Neighborhood Hits	36
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_MOUSE
NC score	0.007710 (rank : 307)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	295	Target Neighborhood Hits	239	Shared Neighborhood Hits	35
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

NEK1_MOUSE
NC score	0.007515 (rank : 308)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	295	Target Neighborhood Hits	1311	Shared Neighborhood Hits	85
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

NEK1_HUMAN
NC score	0.006610 (rank : 309)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	295	Target Neighborhood Hits	1129	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

EPAS1_HUMAN
NC score	0.005263 (rank : 310)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	295	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

TNR21_MOUSE
NC score	0.004785 (rank : 311)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	295	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

PHF2_HUMAN
NC score	0.004590 (rank : 312)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	295	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

BIG2_HUMAN
NC score	0.004474 (rank : 313)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	295	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

ANR52_MOUSE
NC score	0.004278 (rank : 314)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	295	Target Neighborhood Hits	318	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.004253 (rank : 315)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	295	Target Neighborhood Hits	322	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TCF8_MOUSE
NC score	0.002353 (rank : 316)	θ value	0.813845 (rank : 127)
Query Neighborhood Hits	295	Target Neighborhood Hits	1067	Shared Neighborhood Hits	50
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

TCF8_HUMAN
NC score	0.002262 (rank : 317)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	295	Target Neighborhood Hits	1057	Shared Neighborhood Hits	61
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

MASTL_MOUSE
NC score	0.002096 (rank : 318)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	295	Target Neighborhood Hits	862	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

AT11B_HUMAN
NC score	0.001686 (rank : 319)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	295	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G3, Q96FN1, Q9UKK7	Gene names	ATP11B, ATPIF, ATPIR, KIAA0956
Domain Architecture
Description	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase class I type 11B) (ATPase IR).

BACH2_MOUSE
NC score	0.001552 (rank : 320)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	295	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

TLR3_HUMAN
NC score	-0.001501 (rank : 321)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	295	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

EVI1_HUMAN
NC score	-0.004497 (rank : 322)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	295	Target Neighborhood Hits	924	Shared Neighborhood Hits	23
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.