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Network neighborhood for query Sequence : DDX10_HUMAN

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DDX10_HUMAN
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	0 (rank : 2)	NC score	0.990132 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	233	Shared Neighborhood Hits	124
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_MOUSE
θ value	1.59114e-105 (rank : 3)	NC score	0.975916 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX18_HUMAN
θ value	1.34698e-104 (rank : 4)	NC score	0.976488 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX55_HUMAN
θ value	2.31364e-80 (rank : 5)	NC score	0.970416 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	7.44272e-79 (rank : 6)	NC score	0.971286 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX31_HUMAN
θ value	6.76295e-64 (rank : 7)	NC score	0.964436 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX47_HUMAN
θ value	1.19377e-60 (rank : 8)	NC score	0.963735 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	1.19377e-60 (rank : 9)	NC score	0.964009 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX27_HUMAN
θ value	1.15626e-55 (rank : 10)	NC score	0.955870 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	5.73848e-55 (rank : 11)	NC score	0.957863 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	98
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX49_HUMAN
θ value	2.25659e-51 (rank : 12)	NC score	0.955826 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	2.1121e-49 (rank : 13)	NC score	0.958474 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX54_MOUSE
θ value	4.70527e-49 (rank : 14)	NC score	0.951153 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
θ value	1.97686e-47 (rank : 15)	NC score	0.947405 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	170	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX6_HUMAN
θ value	2.18568e-46 (rank : 16)	NC score	0.948938 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	2.18568e-46 (rank : 17)	NC score	0.948754 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	83
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX41_HUMAN
θ value	1.85029e-45 (rank : 18)	NC score	0.947808 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	1.19932e-44 (rank : 19)	NC score	0.947240 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX17_HUMAN
θ value	7.77379e-44 (rank : 20)	NC score	0.940705 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	81
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	7.77379e-44 (rank : 21)	NC score	0.940840 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX21_HUMAN
θ value	1.01529e-43 (rank : 22)	NC score	0.929158 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	308	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX46_HUMAN
θ value	1.73182e-43 (rank : 23)	NC score	0.930761 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	357	Shared Neighborhood Hits	132
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	1.73182e-43 (rank : 24)	NC score	0.928945 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	358	Shared Neighborhood Hits	133
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX50_HUMAN
θ value	1.73182e-43 (rank : 25)	NC score	0.937532 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX4_HUMAN
θ value	2.95404e-43 (rank : 26)	NC score	0.941387 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX5_HUMAN
θ value	3.85808e-43 (rank : 27)	NC score	0.936598 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	5.03882e-43 (rank : 28)	NC score	0.936518 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX4_MOUSE
θ value	1.12253e-42 (rank : 29)	NC score	0.942107 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX50_MOUSE
θ value	1.46607e-42 (rank : 30)	NC score	0.937258 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_MOUSE
θ value	4.2656e-42 (rank : 31)	NC score	0.921050 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	350	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

PL10_MOUSE
θ value	5.57106e-42 (rank : 32)	NC score	0.928613 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	82
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX23_HUMAN
θ value	7.27602e-42 (rank : 33)	NC score	0.929110 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	486	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX3Y_MOUSE
θ value	3.61106e-41 (rank : 34)	NC score	0.928804 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX3X_HUMAN
θ value	4.71619e-41 (rank : 35)	NC score	0.928106 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	82
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX43_HUMAN
θ value	1.3722e-40 (rank : 36)	NC score	0.942852 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX3Y_HUMAN
θ value	1.79215e-40 (rank : 37)	NC score	0.925984 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3X_MOUSE
θ value	3.99248e-40 (rank : 38)	NC score	0.927242 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX56_MOUSE
θ value	2.58786e-39 (rank : 39)	NC score	0.943541 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
θ value	2.86122e-38 (rank : 40)	NC score	0.944310 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	77	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX52_MOUSE
θ value	3.73686e-38 (rank : 41)	NC score	0.944351 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
θ value	1.08726e-37 (rank : 42)	NC score	0.943628 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

IF4A1_HUMAN
θ value	1.85459e-37 (rank : 43)	NC score	0.930916 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	1.85459e-37 (rank : 44)	NC score	0.930916 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	2.42216e-37 (rank : 45)	NC score	0.930427 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	2.42216e-37 (rank : 46)	NC score	0.930427 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX53_HUMAN
θ value	7.04741e-37 (rank : 47)	NC score	0.935991 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX51_MOUSE
θ value	9.20422e-37 (rank : 48)	NC score	0.936157 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	82
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX39_HUMAN
θ value	7.79185e-36 (rank : 49)	NC score	0.933866 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	82
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

UAP56_HUMAN
θ value	2.96089e-35 (rank : 50)	NC score	0.932157 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	2.96089e-35 (rank : 51)	NC score	0.932093 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX48_MOUSE
θ value	8.61488e-35 (rank : 52)	NC score	0.932192 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX39_MOUSE
θ value	1.12514e-34 (rank : 53)	NC score	0.932861 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX48_HUMAN
θ value	1.12514e-34 (rank : 54)	NC score	0.932362 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX51_HUMAN
θ value	1.9192e-34 (rank : 55)	NC score	0.920623 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	332	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX20_HUMAN
θ value	3.06405e-32 (rank : 56)	NC score	0.922301 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	4.00176e-32 (rank : 57)	NC score	0.919301 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX24_HUMAN
θ value	5.77852e-31 (rank : 58)	NC score	0.925860 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX28_HUMAN
θ value	7.54701e-31 (rank : 59)	NC score	0.936957 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX24_MOUSE
θ value	1.6813e-30 (rank : 60)	NC score	0.928125 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX28_MOUSE
θ value	2.68423e-28 (rank : 61)	NC score	0.938153 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX25_MOUSE
θ value	7.80994e-28 (rank : 62)	NC score	0.906261 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
θ value	2.27234e-27 (rank : 63)	NC score	0.906499 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
θ value	2.27234e-27 (rank : 64)	NC score	0.905987 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
θ value	2.96777e-27 (rank : 65)	NC score	0.905663 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_HUMAN
θ value	2.96777e-27 (rank : 66)	NC score	0.907493 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX1_HUMAN
θ value	3.51386e-20 (rank : 67)	NC score	0.865736 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	80
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	4.58923e-20 (rank : 68)	NC score	0.866701 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	80
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

RECQ1_HUMAN
θ value	1.29631e-06 (rank : 69)	NC score	0.434668 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_HUMAN
θ value	8.40245e-06 (rank : 70)	NC score	0.482329 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	8.40245e-06 (rank : 71)	NC score	0.494147 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	75
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ1_MOUSE
θ value	1.87187e-05 (rank : 72)	NC score	0.432744 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
θ value	0.000158464 (rank : 73)	NC score	0.453746 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	390	Shared Neighborhood Hits	81
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FANCM_HUMAN
θ value	0.00102713 (rank : 74)	NC score	0.423928 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	0.00175202 (rank : 75)	NC score	0.419907 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

LEO1_MOUSE
θ value	0.00175202 (rank : 76)	NC score	0.052469 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	946	Shared Neighborhood Hits	55
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

GOGA5_MOUSE
θ value	0.00390308 (rank : 77)	NC score	0.038804 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	1434	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

DICER_HUMAN
θ value	0.00509761 (rank : 78)	NC score	0.390935 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

MYH3_HUMAN
θ value	0.00665767 (rank : 79)	NC score	0.038346 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	1660	Shared Neighborhood Hits	103
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

WRN_HUMAN
θ value	0.00665767 (rank : 80)	NC score	0.449890 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

GOGB1_HUMAN
θ value	0.00869519 (rank : 81)	NC score	0.045715 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	2297	Shared Neighborhood Hits	114
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MY18A_MOUSE
θ value	0.00869519 (rank : 82)	NC score	0.041353 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	1989	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_MOUSE
θ value	0.00869519 (rank : 83)	NC score	0.040361 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	1829	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CK5P2_MOUSE
θ value	0.0113563 (rank : 84)	NC score	0.047038 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	1151	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

DICER_MOUSE
θ value	0.0113563 (rank : 85)	NC score	0.388875 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

U520_HUMAN
θ value	0.0113563 (rank : 86)	NC score	0.153939 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

RECQ4_HUMAN
θ value	0.0148317 (rank : 87)	NC score	0.525703 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

CCD41_MOUSE
θ value	0.0193708 (rank : 88)	NC score	0.044165 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	1399	Shared Neighborhood Hits	103
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CK5P2_HUMAN
θ value	0.0193708 (rank : 89)	NC score	0.047635 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	1433	Shared Neighborhood Hits	96
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

SPTB2_MOUSE
θ value	0.0193708 (rank : 90)	NC score	0.031519 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	770	Shared Neighborhood Hits	63
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

CN145_HUMAN
θ value	0.0431538 (rank : 91)	NC score	0.038167 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	1196	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DHX29_HUMAN
θ value	0.0431538 (rank : 92)	NC score	0.040537 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	144	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

CCD41_HUMAN
θ value	0.0563607 (rank : 93)	NC score	0.040508 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	1139	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

LEO1_HUMAN
θ value	0.0563607 (rank : 94)	NC score	0.047159 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	958	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SDPR_HUMAN
θ value	0.0563607 (rank : 95)	NC score	0.038334 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	41
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SPTB2_HUMAN
θ value	0.0563607 (rank : 96)	NC score	0.031048 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	748	Shared Neighborhood Hits	63
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

GOGA1_HUMAN
θ value	0.0736092 (rank : 97)	NC score	0.032779 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	1222	Shared Neighborhood Hits	86
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

SDPR_MOUSE
θ value	0.0736092 (rank : 98)	NC score	0.042946 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	485	Shared Neighborhood Hits	53
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

RECQ4_MOUSE
θ value	0.0961366 (rank : 99)	NC score	0.506319 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

CI093_HUMAN
θ value	0.125558 (rank : 100)	NC score	0.043289 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	1088	Shared Neighborhood Hits	86
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

GOGA4_HUMAN
θ value	0.125558 (rank : 101)	NC score	0.042292 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	2034	Shared Neighborhood Hits	114
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

ACINU_HUMAN
θ value	0.163984 (rank : 102)	NC score	0.034673 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	828	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MYH6_MOUSE
θ value	0.163984 (rank : 103)	NC score	0.035088 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	1501	Shared Neighborhood Hits	96
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CTRO_MOUSE
θ value	0.21417 (rank : 104)	NC score	0.016559 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	2344	Shared Neighborhood Hits	103
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MY18A_HUMAN
θ value	0.21417 (rank : 105)	NC score	0.040416 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	1929	Shared Neighborhood Hits	115
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_HUMAN
θ value	0.21417 (rank : 106)	NC score	0.037515 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	1762	Shared Neighborhood Hits	106
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TRIPB_HUMAN
θ value	0.21417 (rank : 107)	NC score	0.035982 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	1587	Shared Neighborhood Hits	89
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GRAP1_MOUSE
θ value	0.279714 (rank : 108)	NC score	0.039130 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	1234	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

LIPB1_MOUSE
θ value	0.279714 (rank : 109)	NC score	0.026426 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	727	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

NASP_HUMAN
θ value	0.279714 (rank : 110)	NC score	0.047052 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	709	Shared Neighborhood Hits	65
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

STK10_MOUSE
θ value	0.279714 (rank : 111)	NC score	0.010847 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	2132	Shared Neighborhood Hits	98
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

PLCB2_HUMAN
θ value	0.365318 (rank : 112)	NC score	0.027680 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	608	Shared Neighborhood Hits	71
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

ZO2_HUMAN
θ value	0.365318 (rank : 113)	NC score	0.007486 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

KIF14_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.016643 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	732	Shared Neighborhood Hits	73
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KTN1_MOUSE
θ value	0.47712 (rank : 115)	NC score	0.036886 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	1324	Shared Neighborhood Hits	90
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PCLO_HUMAN
θ value	0.47712 (rank : 116)	NC score	0.016096 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	2046	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RCOR3_HUMAN
θ value	0.47712 (rank : 117)	NC score	0.010003 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

SAS6_MOUSE
θ value	0.47712 (rank : 118)	NC score	0.031425 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	931	Shared Neighborhood Hits	71
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SKIV2_HUMAN
θ value	0.47712 (rank : 119)	NC score	0.061552 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

STMN4_HUMAN
θ value	0.47712 (rank : 120)	NC score	0.031753 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	0.47712 (rank : 121)	NC score	0.031746 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

SYNE2_HUMAN
θ value	0.47712 (rank : 122)	NC score	0.036176 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	1323	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

NEB1_HUMAN
θ value	0.62314 (rank : 123)	NC score	0.025653 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	829	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

STK10_HUMAN
θ value	0.62314 (rank : 124)	NC score	0.007702 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	1921	Shared Neighborhood Hits	83
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYH1_HUMAN
θ value	0.813845 (rank : 125)	NC score	0.034941 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	1478	Shared Neighborhood Hits	97
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

REST_MOUSE
θ value	0.813845 (rank : 126)	NC score	0.035066 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	1506	Shared Neighborhood Hits	103
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

BPA1_MOUSE
θ value	1.06291 (rank : 127)	NC score	0.031427 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	1477	Shared Neighborhood Hits	87
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CF060_HUMAN
θ value	1.06291 (rank : 128)	NC score	0.041000 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	1270	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DNAI2_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.017112 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

TAOK1_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.007988 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	1720	Shared Neighborhood Hits	87
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

UACA_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.025334 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	1622	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

BPAEA_HUMAN
θ value	1.38821 (rank : 132)	NC score	0.033512 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	1369	Shared Neighborhood Hits	89
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYH7_HUMAN
θ value	1.38821 (rank : 133)	NC score	0.033768 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	1559	Shared Neighborhood Hits	95
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

TAOK1_HUMAN
θ value	1.38821 (rank : 134)	NC score	0.008764 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	1734	Shared Neighborhood Hits	87
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

CCD11_MOUSE
θ value	1.81305 (rank : 135)	NC score	0.040216 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	498	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

FA21C_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.031423 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	194	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

MYT1L_HUMAN
θ value	1.81305 (rank : 137)	NC score	0.023943 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	471	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NOP14_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.052695 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	573	Shared Neighborhood Hits	73
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

OXR1_HUMAN
θ value	1.81305 (rank : 139)	NC score	0.018453 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

PPIG_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.036661 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	670	Shared Neighborhood Hits	83
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SM1L2_HUMAN
θ value	1.81305 (rank : 141)	NC score	0.032776 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	1019	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SPC24_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.026427 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	324	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

CCD46_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.033621 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	1405	Shared Neighborhood Hits	98
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GOGA5_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.034011 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	1168	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SH24A_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.018572 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	455	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SMC2_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.036142 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	1405	Shared Neighborhood Hits	105
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

AUHM_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.008984 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

CCNB3_MOUSE
θ value	3.0926 (rank : 148)	NC score	0.009927 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CEP35_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.031744 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	811	Shared Neighborhood Hits	84
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CT2NL_MOUSE
θ value	3.0926 (rank : 150)	NC score	0.037608 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	902	Shared Neighborhood Hits	79
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

EEA1_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.035128 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	1637	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GLE1_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.029320 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	504	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

IFIH1_MOUSE
θ value	3.0926 (rank : 153)	NC score	0.276063 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

IWS1_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.033768 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	1241	Shared Neighborhood Hits	69
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MAP9_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.039462 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	518	Shared Neighborhood Hits	84
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NIPBL_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.040285 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	1311	Shared Neighborhood Hits	70
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PIBF1_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.033166 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	1041	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

RAD50_MOUSE
θ value	3.0926 (rank : 158)	NC score	0.034237 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	1366	Shared Neighborhood Hits	94
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TITIN_HUMAN
θ value	3.0926 (rank : 159)	NC score	-0.005450 (rank : 219)
Query Neighborhood Hits	210	Target Neighborhood Hits	2923	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN694_HUMAN
θ value	3.0926 (rank : 160)	NC score	-0.007849 (rank : 220)
Query Neighborhood Hits	210	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

ANR26_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.028271 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	1614	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BPAEA_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.034015 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	1480	Shared Neighborhood Hits	99
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CUTL2_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.016857 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DYXC1_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.006409 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	172	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

IWS1_MOUSE
θ value	4.03905 (rank : 165)	NC score	0.028387 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	1258	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.015095 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	1514	Shared Neighborhood Hits	57
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYH6_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.032596 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	1426	Shared Neighborhood Hits	94
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NKX61_MOUSE
θ value	4.03905 (rank : 168)	NC score	-0.003153 (rank : 218)
Query Neighborhood Hits	210	Target Neighborhood Hits	439	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NOL8_HUMAN
θ value	4.03905 (rank : 169)	NC score	0.023011 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

RB6I2_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.035931 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	1584	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RBM25_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.043922 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	682	Shared Neighborhood Hits	85
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SMC2_MOUSE
θ value	4.03905 (rank : 172)	NC score	0.033862 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	1131	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

STX1B_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.015636 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	252	Shared Neighborhood Hits	43
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

SYCP2_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.017347 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TOP2B_HUMAN
θ value	4.03905 (rank : 175)	NC score	0.006449 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

AUMH_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.007953 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

BNC2_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.006069 (rank : 211)
Query Neighborhood Hits	210	Target Neighborhood Hits	456	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CCD45_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.031194 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	525	Shared Neighborhood Hits	60
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CENPC_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.010980 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

BNC2_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.005250 (rank : 212)
Query Neighborhood Hits	210	Target Neighborhood Hits	439	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

C8AP2_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.021523 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	548	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CCD55_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.051405 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	513	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD93_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.028232 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	600	Shared Neighborhood Hits	65
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

DMD_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.031730 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	1111	Shared Neighborhood Hits	85
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ES8L2_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.001326 (rank : 216)
Query Neighborhood Hits	210	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

FLOT1_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.018295 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	142	Shared Neighborhood Hits	37
SwissProt Accessions	O75955, Q969J8, Q9UHW1, Q9UNV8	Gene names	FLOT1
Domain Architecture
Description	Flotillin-1.

FLOT1_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.017247 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	O08917	Gene names	Flot1
Domain Architecture
Description	Flotillin-1.

GFAP_MOUSE
θ value	6.88961 (rank : 188)	NC score	0.010876 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	725	Shared Neighborhood Hits	65
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

MPP8_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.040419 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	948	Shared Neighborhood Hits	77
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

PALB2_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.015349 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PLCB3_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.017973 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	445	Shared Neighborhood Hits	57
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PPIA_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.003511 (rank : 215)
Query Neighborhood Hits	210	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

PPIA_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.003511 (rank : 214)
Query Neighborhood Hits	210	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

RAI14_MOUSE
θ value	6.88961 (rank : 194)	NC score	0.021232 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	1505	Shared Neighborhood Hits	100
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RRBP1_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.037362 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	1306	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SCG2_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.020008 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SK2L2_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.031966 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

STX1C_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.017379 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
θ value	6.88961 (rank : 199)	NC score	0.017379 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

CMGA_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.035675 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CS029_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.015502 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	329	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

CT2NL_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.039449 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	1059	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DMD_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.029536 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	1135	Shared Neighborhood Hits	77
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EEA1_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.031163 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	1796	Shared Neighborhood Hits	99
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

LAMB1_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.013766 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	1018	Shared Neighborhood Hits	67
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MIA2_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.004511 (rank : 213)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

MRP6_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.000617 (rank : 217)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

NOP14_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.023369 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	324	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

STMN1_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.035307 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TXND2_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.042787 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	828	Shared Neighborhood Hits	66
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CC026_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.149409 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.117709 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX58_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.146078 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.178221 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

HELC1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.102739 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	71	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

IFIH1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.287917 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.277688 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.290907 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	67
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

SMAL1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.067819 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

WRN_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.405932 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	295	Shared Neighborhood Hits	104
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

Hits sorted by NC score

DDX10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
NC score	0.990132 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	233	Shared Neighborhood Hits	124
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
NC score	0.976488 (rank : 3)	θ value	1.34698e-104 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX18_MOUSE
NC score	0.975916 (rank : 4)	θ value	1.59114e-105 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX55_MOUSE
NC score	0.971286 (rank : 5)	θ value	7.44272e-79 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.970416 (rank : 6)	θ value	2.31364e-80 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX31_HUMAN
NC score	0.964436 (rank : 7)	θ value	6.76295e-64 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX47_MOUSE
NC score	0.964009 (rank : 8)	θ value	1.19377e-60 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.963735 (rank : 9)	θ value	1.19377e-60 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.958474 (rank : 10)	θ value	2.1121e-49 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
NC score	0.957863 (rank : 11)	θ value	5.73848e-55 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	98
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.955870 (rank : 12)	θ value	1.15626e-55 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX49_HUMAN
NC score	0.955826 (rank : 13)	θ value	2.25659e-51 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX54_MOUSE
NC score	0.951153 (rank : 14)	θ value	4.70527e-49 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX6_HUMAN
NC score	0.948938 (rank : 15)	θ value	2.18568e-46 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.948754 (rank : 16)	θ value	2.18568e-46 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	83
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX41_HUMAN
NC score	0.947808 (rank : 17)	θ value	1.85029e-45 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX54_HUMAN
NC score	0.947405 (rank : 18)	θ value	1.97686e-47 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	170	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX41_MOUSE
NC score	0.947240 (rank : 19)	θ value	1.19932e-44 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX52_MOUSE
NC score	0.944351 (rank : 20)	θ value	3.73686e-38 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX56_HUMAN
NC score	0.944310 (rank : 21)	θ value	2.86122e-38 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	77	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX52_HUMAN
NC score	0.943628 (rank : 22)	θ value	1.08726e-37 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX56_MOUSE
NC score	0.943541 (rank : 23)	θ value	2.58786e-39 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX43_HUMAN
NC score	0.942852 (rank : 24)	θ value	1.3722e-40 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX4_MOUSE
NC score	0.942107 (rank : 25)	θ value	1.12253e-42 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX4_HUMAN
NC score	0.941387 (rank : 26)	θ value	2.95404e-43 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX17_MOUSE
NC score	0.940840 (rank : 27)	θ value	7.77379e-44 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.940705 (rank : 28)	θ value	7.77379e-44 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	81
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX28_MOUSE
NC score	0.938153 (rank : 29)	θ value	2.68423e-28 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX50_HUMAN
NC score	0.937532 (rank : 30)	θ value	1.73182e-43 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.937258 (rank : 31)	θ value	1.46607e-42 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX28_HUMAN
NC score	0.936957 (rank : 32)	θ value	7.54701e-31 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX5_HUMAN
NC score	0.936598 (rank : 33)	θ value	3.85808e-43 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.936518 (rank : 34)	θ value	5.03882e-43 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX51_MOUSE
NC score	0.936157 (rank : 35)	θ value	9.20422e-37 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	82
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX53_HUMAN
NC score	0.935991 (rank : 36)	θ value	7.04741e-37 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX39_HUMAN
NC score	0.933866 (rank : 37)	θ value	7.79185e-36 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	82
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
NC score	0.932861 (rank : 38)	θ value	1.12514e-34 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX48_HUMAN
NC score	0.932362 (rank : 39)	θ value	1.12514e-34 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.932192 (rank : 40)	θ value	8.61488e-35 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

UAP56_HUMAN
NC score	0.932157 (rank : 41)	θ value	2.96089e-35 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.932093 (rank : 42)	θ value	2.96089e-35 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

IF4A1_HUMAN
NC score	0.930916 (rank : 43)	θ value	1.85459e-37 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.930916 (rank : 44)	θ value	1.85459e-37 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX46_HUMAN
NC score	0.930761 (rank : 45)	θ value	1.73182e-43 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	357	Shared Neighborhood Hits	132
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

IF4A2_HUMAN
NC score	0.930427 (rank : 46)	θ value	2.42216e-37 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.930427 (rank : 47)	θ value	2.42216e-37 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX21_HUMAN
NC score	0.929158 (rank : 48)	θ value	1.01529e-43 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	308	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX23_HUMAN
NC score	0.929110 (rank : 49)	θ value	7.27602e-42 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	486	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX46_MOUSE
NC score	0.928945 (rank : 50)	θ value	1.73182e-43 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	358	Shared Neighborhood Hits	133
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX3Y_MOUSE
NC score	0.928804 (rank : 51)	θ value	3.61106e-41 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

PL10_MOUSE
NC score	0.928613 (rank : 52)	θ value	5.57106e-42 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	82
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX24_MOUSE
NC score	0.928125 (rank : 53)	θ value	1.6813e-30 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX3X_HUMAN
NC score	0.928106 (rank : 54)	θ value	4.71619e-41 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	82
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
NC score	0.927242 (rank : 55)	θ value	3.99248e-40 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
NC score	0.925984 (rank : 56)	θ value	1.79215e-40 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX24_HUMAN
NC score	0.925860 (rank : 57)	θ value	5.77852e-31 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX20_HUMAN
NC score	0.922301 (rank : 58)	θ value	3.06405e-32 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX21_MOUSE
NC score	0.921050 (rank : 59)	θ value	4.2656e-42 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	350	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX51_HUMAN
NC score	0.920623 (rank : 60)	θ value	1.9192e-34 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	332	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX20_MOUSE
NC score	0.919301 (rank : 61)	θ value	4.00176e-32 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX25_HUMAN
NC score	0.907493 (rank : 62)	θ value	2.96777e-27 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
NC score	0.906499 (rank : 63)	θ value	2.27234e-27 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX25_MOUSE
NC score	0.906261 (rank : 64)	θ value	7.80994e-28 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19B_HUMAN
NC score	0.905987 (rank : 65)	θ value	2.27234e-27 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.905663 (rank : 66)	θ value	2.96777e-27 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX1_MOUSE
NC score	0.866701 (rank : 67)	θ value	4.58923e-20 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	80
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.865736 (rank : 68)	θ value	3.51386e-20 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	80
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.525703 (rank : 69)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.506319 (rank : 70)	θ value	0.0961366 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.494147 (rank : 71)	θ value	8.40245e-06 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	75
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.482329 (rank : 72)	θ value	8.40245e-06 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.453746 (rank : 73)	θ value	0.000158464 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	390	Shared Neighborhood Hits	81
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
NC score	0.449890 (rank : 74)	θ value	0.00665767 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ1_HUMAN
NC score	0.434668 (rank : 75)	θ value	1.29631e-06 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.432744 (rank : 76)	θ value	1.87187e-05 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

FANCM_HUMAN
NC score	0.423928 (rank : 77)	θ value	0.00102713 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.419907 (rank : 78)	θ value	0.00175202 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

WRN_MOUSE
NC score	0.405932 (rank : 79)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	210	Target Neighborhood Hits	295	Shared Neighborhood Hits	104
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DICER_HUMAN
NC score	0.390935 (rank : 80)	θ value	0.00509761 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.388875 (rank : 81)	θ value	0.0113563 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

LGP2_MOUSE
NC score	0.290907 (rank : 82)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	67
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_HUMAN
NC score	0.287917 (rank : 83)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.277688 (rank : 84)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_MOUSE
NC score	0.276063 (rank : 85)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.178221 (rank : 86)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

U520_HUMAN
NC score	0.153939 (rank : 87)	θ value	0.0113563 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_HUMAN
NC score	0.149409 (rank : 88)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX58_HUMAN
NC score	0.146078 (rank : 89)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_MOUSE
NC score	0.117709 (rank : 90)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	210	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

HELC1_HUMAN
NC score	0.102739 (rank : 91)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	210	Target Neighborhood Hits	71	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
NC score	0.067819 (rank : 92)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SKIV2_HUMAN
NC score	0.061552 (rank : 93)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

NOP14_HUMAN
NC score	0.052695 (rank : 94)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	573	Shared Neighborhood Hits	73
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

LEO1_MOUSE
NC score	0.052469 (rank : 95)	θ value	0.00175202 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	946	Shared Neighborhood Hits	55
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CCD55_HUMAN
NC score	0.051405 (rank : 96)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	513	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CK5P2_HUMAN
NC score	0.047635 (rank : 97)	θ value	0.0193708 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	1433	Shared Neighborhood Hits	96
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

LEO1_HUMAN
NC score	0.047159 (rank : 98)	θ value	0.0563607 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	958	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NASP_HUMAN
NC score	0.047052 (rank : 99)	θ value	0.279714 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	709	Shared Neighborhood Hits	65
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

CK5P2_MOUSE
NC score	0.047038 (rank : 100)	θ value	0.0113563 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	1151	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

GOGB1_HUMAN
NC score	0.045715 (rank : 101)	θ value	0.00869519 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	2297	Shared Neighborhood Hits	114
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCD41_MOUSE
NC score	0.044165 (rank : 102)	θ value	0.0193708 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	1399	Shared Neighborhood Hits	103
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

RBM25_HUMAN
NC score	0.043922 (rank : 103)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	682	Shared Neighborhood Hits	85
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

CI093_HUMAN
NC score	0.043289 (rank : 104)	θ value	0.125558 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	1088	Shared Neighborhood Hits	86
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

SDPR_MOUSE
NC score	0.042946 (rank : 105)	θ value	0.0736092 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	485	Shared Neighborhood Hits	53
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TXND2_MOUSE
NC score	0.042787 (rank : 106)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	828	Shared Neighborhood Hits	66
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

GOGA4_HUMAN
NC score	0.042292 (rank : 107)	θ value	0.125558 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	2034	Shared Neighborhood Hits	114
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MY18A_MOUSE
NC score	0.041353 (rank : 108)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	1989	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CF060_HUMAN
NC score	0.041000 (rank : 109)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	1270	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DHX29_HUMAN
NC score	0.040537 (rank : 110)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	144	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

CCD41_HUMAN
NC score	0.040508 (rank : 111)	θ value	0.0563607 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	1139	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

MPP8_HUMAN
NC score	0.040419 (rank : 112)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	948	Shared Neighborhood Hits	77
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MY18A_HUMAN
NC score	0.040416 (rank : 113)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	1929	Shared Neighborhood Hits	115
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_MOUSE
NC score	0.040361 (rank : 114)	θ value	0.00869519 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	1829	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NIPBL_HUMAN
NC score	0.040285 (rank : 115)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	1311	Shared Neighborhood Hits	70
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CCD11_MOUSE
NC score	0.040216 (rank : 116)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	498	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

MAP9_HUMAN
NC score	0.039462 (rank : 117)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	518	Shared Neighborhood Hits	84
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CT2NL_HUMAN
NC score	0.039449 (rank : 118)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	1059	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

GRAP1_MOUSE
NC score	0.039130 (rank : 119)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	1234	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GOGA5_MOUSE
NC score	0.038804 (rank : 120)	θ value	0.00390308 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	1434	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MYH3_HUMAN
NC score	0.038346 (rank : 121)	θ value	0.00665767 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	1660	Shared Neighborhood Hits	103
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

SDPR_HUMAN
NC score	0.038334 (rank : 122)	θ value	0.0563607 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	41
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

CN145_HUMAN
NC score	0.038167 (rank : 123)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	1196	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CT2NL_MOUSE
NC score	0.037608 (rank : 124)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	902	Shared Neighborhood Hits	79
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MYH9_HUMAN
NC score	0.037515 (rank : 125)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	1762	Shared Neighborhood Hits	106
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RRBP1_HUMAN
NC score	0.037362 (rank : 126)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	1306	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

KTN1_MOUSE
NC score	0.036886 (rank : 127)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	1324	Shared Neighborhood Hits	90
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PPIG_HUMAN
NC score	0.036661 (rank : 128)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	670	Shared Neighborhood Hits	83
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SYNE2_HUMAN
NC score	0.036176 (rank : 129)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	1323	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SMC2_HUMAN
NC score	0.036142 (rank : 130)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	1405	Shared Neighborhood Hits	105
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TRIPB_HUMAN
NC score	0.035982 (rank : 131)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	1587	Shared Neighborhood Hits	89
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

RB6I2_HUMAN
NC score	0.035931 (rank : 132)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	1584	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CMGA_HUMAN
NC score	0.035675 (rank : 133)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

STMN1_MOUSE
NC score	0.035307 (rank : 134)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

EEA1_MOUSE
NC score	0.035128 (rank : 135)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	1637	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MYH6_MOUSE
NC score	0.035088 (rank : 136)	θ value	0.163984 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	1501	Shared Neighborhood Hits	96
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

REST_MOUSE
NC score	0.035066 (rank : 137)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	1506	Shared Neighborhood Hits	103
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

MYH1_HUMAN
NC score	0.034941 (rank : 138)	θ value	0.813845 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	1478	Shared Neighborhood Hits	97
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

ACINU_HUMAN
NC score	0.034673 (rank : 139)	θ value	0.163984 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	828	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RAD50_MOUSE
NC score	0.034237 (rank : 140)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	1366	Shared Neighborhood Hits	94
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

BPAEA_MOUSE
NC score	0.034015 (rank : 141)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	1480	Shared Neighborhood Hits	99
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGA5_HUMAN
NC score	0.034011 (rank : 142)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	1168	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SMC2_MOUSE
NC score	0.033862 (rank : 143)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	1131	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MYH7_HUMAN
NC score	0.033768 (rank : 144)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	1559	Shared Neighborhood Hits	95
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

IWS1_HUMAN
NC score	0.033768 (rank : 145)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	1241	Shared Neighborhood Hits	69
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CCD46_MOUSE
NC score	0.033621 (rank : 146)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	1405	Shared Neighborhood Hits	98
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

BPAEA_HUMAN
NC score	0.033512 (rank : 147)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	1369	Shared Neighborhood Hits	89
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PIBF1_HUMAN
NC score	0.033166 (rank : 148)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	1041	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

GOGA1_HUMAN
NC score	0.032779 (rank : 149)	θ value	0.0736092 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	1222	Shared Neighborhood Hits	86
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

SM1L2_HUMAN
NC score	0.032776 (rank : 150)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	1019	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

MYH6_HUMAN
NC score	0.032596 (rank : 151)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	1426	Shared Neighborhood Hits	94
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SK2L2_HUMAN
NC score	0.031966 (rank : 152)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

STMN4_HUMAN
NC score	0.031753 (rank : 153)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.031746 (rank : 154)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

CEP35_HUMAN
NC score	0.031744 (rank : 155)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	811	Shared Neighborhood Hits	84
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

DMD_MOUSE
NC score	0.031730 (rank : 156)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	1111	Shared Neighborhood Hits	85
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

SPTB2_MOUSE
NC score	0.031519 (rank : 157)	θ value	0.0193708 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	770	Shared Neighborhood Hits	63
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

BPA1_MOUSE
NC score	0.031427 (rank : 158)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	1477	Shared Neighborhood Hits	87
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SAS6_MOUSE
NC score	0.031425 (rank : 159)	θ value	0.47712 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	931	Shared Neighborhood Hits	71
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

FA21C_HUMAN
NC score	0.031423 (rank : 160)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	194	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

CCD45_HUMAN
NC score	0.031194 (rank : 161)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	525	Shared Neighborhood Hits	60
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

EEA1_HUMAN
NC score	0.031163 (rank : 162)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	1796	Shared Neighborhood Hits	99
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SPTB2_HUMAN
NC score	0.031048 (rank : 163)	θ value	0.0563607 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	748	Shared Neighborhood Hits	63
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

DMD_HUMAN
NC score	0.029536 (rank : 164)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	1135	Shared Neighborhood Hits	77
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GLE1_MOUSE
NC score	0.029320 (rank : 165)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	504	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

IWS1_MOUSE
NC score	0.028387 (rank : 166)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	1258	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ANR26_HUMAN
NC score	0.028271 (rank : 167)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	1614	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CCD93_HUMAN
NC score	0.028232 (rank : 168)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	600	Shared Neighborhood Hits	65
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

PLCB2_HUMAN
NC score	0.027680 (rank : 169)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	608	Shared Neighborhood Hits	71
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

SPC24_HUMAN
NC score	0.026427 (rank : 170)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	324	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

LIPB1_MOUSE
NC score	0.026426 (rank : 171)	θ value	0.279714 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	727	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

NEB1_HUMAN
NC score	0.025653 (rank : 172)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	829	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

UACA_HUMAN
NC score	0.025334 (rank : 173)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	1622	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MYT1L_HUMAN
NC score	0.023943 (rank : 174)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	471	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NOP14_MOUSE
NC score	0.023369 (rank : 175)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	324	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NOL8_HUMAN
NC score	0.023011 (rank : 176)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

C8AP2_HUMAN
NC score	0.021523 (rank : 177)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	548	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

RAI14_MOUSE
NC score	0.021232 (rank : 178)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	1505	Shared Neighborhood Hits	100
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SCG2_HUMAN
NC score	0.020008 (rank : 179)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SH24A_HUMAN
NC score	0.018572 (rank : 180)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	455	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

OXR1_HUMAN
NC score	0.018453 (rank : 181)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

FLOT1_HUMAN
NC score	0.018295 (rank : 182)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	142	Shared Neighborhood Hits	37
SwissProt Accessions	O75955, Q969J8, Q9UHW1, Q9UNV8	Gene names	FLOT1
Domain Architecture
Description	Flotillin-1.

PLCB3_HUMAN
NC score	0.017973 (rank : 183)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	445	Shared Neighborhood Hits	57
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

STX1C_HUMAN
NC score	0.017379 (rank : 184)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
NC score	0.017379 (rank : 185)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

SYCP2_HUMAN
NC score	0.017347 (rank : 186)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

FLOT1_MOUSE
NC score	0.017247 (rank : 187)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	O08917	Gene names	Flot1
Domain Architecture
Description	Flotillin-1.

DNAI2_HUMAN
NC score	0.017112 (rank : 188)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

CUTL2_HUMAN
NC score	0.016857 (rank : 189)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

KIF14_HUMAN
NC score	0.016643 (rank : 190)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	732	Shared Neighborhood Hits	73
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

CTRO_MOUSE
NC score	0.016559 (rank : 191)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	2344	Shared Neighborhood Hits	103
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PCLO_HUMAN
NC score	0.016096 (rank : 192)	θ value	0.47712 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	2046	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

STX1B_HUMAN
NC score	0.015636 (rank : 193)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	252	Shared Neighborhood Hits	43
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

CS029_HUMAN
NC score	0.015502 (rank : 194)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	329	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

PALB2_HUMAN
NC score	0.015349 (rank : 195)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

MINT_MOUSE
NC score	0.015095 (rank : 196)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	1514	Shared Neighborhood Hits	57
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

LAMB1_HUMAN
NC score	0.013766 (rank : 197)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	1018	Shared Neighborhood Hits	67
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CENPC_HUMAN
NC score	0.010980 (rank : 198)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

GFAP_MOUSE
NC score	0.010876 (rank : 199)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	725	Shared Neighborhood Hits	65
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

STK10_MOUSE
NC score	0.010847 (rank : 200)	θ value	0.279714 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	2132	Shared Neighborhood Hits	98
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

RCOR3_HUMAN
NC score	0.010003 (rank : 201)	θ value	0.47712 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

CCNB3_MOUSE
NC score	0.009927 (rank : 202)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

AUHM_MOUSE
NC score	0.008984 (rank : 203)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

TAOK1_HUMAN
NC score	0.008764 (rank : 204)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	1734	Shared Neighborhood Hits	87
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
NC score	0.007988 (rank : 205)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	1720	Shared Neighborhood Hits	87
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

AUMH_HUMAN
NC score	0.007953 (rank : 206)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

STK10_HUMAN
NC score	0.007702 (rank : 207)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	1921	Shared Neighborhood Hits	83
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZO2_HUMAN
NC score	0.007486 (rank : 208)	θ value	0.365318 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

TOP2B_HUMAN
NC score	0.006449 (rank : 209)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

DYXC1_MOUSE
NC score	0.006409 (rank : 210)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	172	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

BNC2_MOUSE
NC score	0.006069 (rank : 211)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	456	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BNC2_HUMAN
NC score	0.005250 (rank : 212)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	439	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

MIA2_MOUSE
NC score	0.004511 (rank : 213)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

PPIA_MOUSE
NC score	0.003511 (rank : 214)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIA_HUMAN
NC score	0.003511 (rank : 215)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

ES8L2_MOUSE
NC score	0.001326 (rank : 216)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

MRP6_MOUSE
NC score	0.000617 (rank : 217)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

NKX61_MOUSE
NC score	-0.003153 (rank : 218)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	439	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

TITIN_HUMAN
NC score	-0.005450 (rank : 219)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	2923	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN694_HUMAN
NC score	-0.007849 (rank : 220)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.