Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ZO2_HUMAN

For an explanation of this page, click here

ZO2_HUMAN
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZO1_HUMAN
θ value	0 (rank : 1)	NC score	0.914099 (rank : 6)
Query Neighborhood Hits	289	Target Neighborhood Hits	474	Shared Neighborhood Hits	183
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	0 (rank : 2)	NC score	0.915294 (rank : 5)
Query Neighborhood Hits	289	Target Neighborhood Hits	453	Shared Neighborhood Hits	185
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	289
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	0 (rank : 4)	NC score	0.986889 (rank : 2)
Query Neighborhood Hits	289	Target Neighborhood Hits	296	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
θ value	6.59259e-152 (rank : 5)	NC score	0.946385 (rank : 3)
Query Neighborhood Hits	289	Target Neighborhood Hits	219	Shared Neighborhood Hits	167
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
θ value	8.63019e-144 (rank : 6)	NC score	0.942803 (rank : 4)
Query Neighborhood Hits	289	Target Neighborhood Hits	224	Shared Neighborhood Hits	171
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

DLG2_MOUSE
θ value	8.06329e-33 (rank : 7)	NC score	0.738097 (rank : 7)
Query Neighborhood Hits	289	Target Neighborhood Hits	271	Shared Neighborhood Hits	161
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG5_HUMAN
θ value	4.00176e-32 (rank : 8)	NC score	0.548156 (rank : 27)
Query Neighborhood Hits	289	Target Neighborhood Hits	1088	Shared Neighborhood Hits	183
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DLG2_HUMAN
θ value	1.98606e-31 (rank : 9)	NC score	0.737466 (rank : 8)
Query Neighborhood Hits	289	Target Neighborhood Hits	279	Shared Neighborhood Hits	163
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	5.40856e-29 (rank : 10)	NC score	0.732776 (rank : 11)
Query Neighborhood Hits	289	Target Neighborhood Hits	269	Shared Neighborhood Hits	168
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_MOUSE
θ value	1.2049e-28 (rank : 11)	NC score	0.730665 (rank : 13)
Query Neighborhood Hits	289	Target Neighborhood Hits	285	Shared Neighborhood Hits	159
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG4_HUMAN
θ value	1.2049e-28 (rank : 12)	NC score	0.735475 (rank : 10)
Query Neighborhood Hits	289	Target Neighborhood Hits	286	Shared Neighborhood Hits	167
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	1.57365e-28 (rank : 13)	NC score	0.736510 (rank : 9)
Query Neighborhood Hits	289	Target Neighborhood Hits	282	Shared Neighborhood Hits	167
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG3_MOUSE
θ value	4.57862e-28 (rank : 14)	NC score	0.731529 (rank : 12)
Query Neighborhood Hits	289	Target Neighborhood Hits	274	Shared Neighborhood Hits	169
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_HUMAN
θ value	5.97985e-28 (rank : 15)	NC score	0.728583 (rank : 14)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	159
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

PTN13_HUMAN
θ value	1.86753e-13 (rank : 16)	NC score	0.363964 (rank : 92)
Query Neighborhood Hits	289	Target Neighborhood Hits	471	Shared Neighborhood Hits	173
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CAR14_HUMAN
θ value	7.09661e-13 (rank : 17)	NC score	0.282142 (rank : 117)
Query Neighborhood Hits	289	Target Neighborhood Hits	449	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

MPP5_HUMAN
θ value	1.2105e-12 (rank : 18)	NC score	0.558863 (rank : 23)
Query Neighborhood Hits	289	Target Neighborhood Hits	231	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	1.58096e-12 (rank : 19)	NC score	0.558499 (rank : 24)
Query Neighborhood Hits	289	Target Neighborhood Hits	226	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

INADL_MOUSE
θ value	3.64472e-09 (rank : 20)	NC score	0.607737 (rank : 16)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	177
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LAP4_HUMAN
θ value	1.38499e-08 (rank : 21)	NC score	0.402593 (rank : 86)
Query Neighborhood Hits	289	Target Neighborhood Hits	608	Shared Neighborhood Hits	178
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

CAR11_HUMAN
θ value	1.80886e-08 (rank : 22)	NC score	0.248784 (rank : 136)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

PTN13_MOUSE
θ value	1.80886e-08 (rank : 23)	NC score	0.358024 (rank : 93)
Query Neighborhood Hits	289	Target Neighborhood Hits	426	Shared Neighborhood Hits	179
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

LAP4_MOUSE
θ value	2.36244e-08 (rank : 24)	NC score	0.399876 (rank : 88)
Query Neighborhood Hits	289	Target Neighborhood Hits	590	Shared Neighborhood Hits	182
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

INADL_HUMAN
θ value	8.97725e-08 (rank : 25)	NC score	0.593217 (rank : 17)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	171
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

GOPC_MOUSE
θ value	1.17247e-07 (rank : 26)	NC score	0.530392 (rank : 35)
Query Neighborhood Hits	289	Target Neighborhood Hits	323	Shared Neighborhood Hits	151
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

CAR14_MOUSE
θ value	1.99992e-07 (rank : 27)	NC score	0.244100 (rank : 140)
Query Neighborhood Hits	289	Target Neighborhood Hits	526	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

MPP2_MOUSE
θ value	1.99992e-07 (rank : 28)	NC score	0.457851 (rank : 70)
Query Neighborhood Hits	289	Target Neighborhood Hits	189	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

SNTA1_MOUSE
θ value	3.41135e-07 (rank : 29)	NC score	0.489670 (rank : 59)
Query Neighborhood Hits	289	Target Neighborhood Hits	170	Shared Neighborhood Hits	141
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

MPP2_HUMAN
θ value	4.45536e-07 (rank : 30)	NC score	0.454341 (rank : 73)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	88
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

LAP2_HUMAN
θ value	5.81887e-07 (rank : 31)	NC score	0.242669 (rank : 141)
Query Neighborhood Hits	289	Target Neighborhood Hits	499	Shared Neighborhood Hits	116
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MPDZ_HUMAN
θ value	5.81887e-07 (rank : 32)	NC score	0.572367 (rank : 21)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	174
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
θ value	5.81887e-07 (rank : 33)	NC score	0.573376 (rank : 20)
Query Neighborhood Hits	289	Target Neighborhood Hits	298	Shared Neighborhood Hits	172
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

GRIP1_HUMAN
θ value	7.59969e-07 (rank : 34)	NC score	0.546633 (rank : 28)
Query Neighborhood Hits	289	Target Neighborhood Hits	231	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LAP2_MOUSE
θ value	7.59969e-07 (rank : 35)	NC score	0.234550 (rank : 145)
Query Neighborhood Hits	289	Target Neighborhood Hits	482	Shared Neighborhood Hits	109
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GOPC_HUMAN
θ value	9.92553e-07 (rank : 36)	NC score	0.520241 (rank : 41)
Query Neighborhood Hits	289	Target Neighborhood Hits	377	Shared Neighborhood Hits	152
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTB2_HUMAN
θ value	9.92553e-07 (rank : 37)	NC score	0.504408 (rank : 52)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	143
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	9.92553e-07 (rank : 38)	NC score	0.504888 (rank : 50)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	143
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

WHRN_HUMAN
θ value	9.92553e-07 (rank : 39)	NC score	0.562561 (rank : 22)
Query Neighborhood Hits	289	Target Neighborhood Hits	325	Shared Neighborhood Hits	176
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	9.92553e-07 (rank : 40)	NC score	0.553074 (rank : 25)
Query Neighborhood Hits	289	Target Neighborhood Hits	412	Shared Neighborhood Hits	176
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

SNTA1_HUMAN
θ value	1.29631e-06 (rank : 41)	NC score	0.492539 (rank : 58)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	148
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

GRIP1_MOUSE
θ value	4.92598e-06 (rank : 42)	NC score	0.542414 (rank : 31)
Query Neighborhood Hits	289	Target Neighborhood Hits	241	Shared Neighborhood Hits	171
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SYJ2B_HUMAN
θ value	4.92598e-06 (rank : 43)	NC score	0.639636 (rank : 15)
Query Neighborhood Hits	289	Target Neighborhood Hits	162	Shared Neighborhood Hits	142
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LNX2_MOUSE
θ value	6.43352e-06 (rank : 44)	NC score	0.526358 (rank : 39)
Query Neighborhood Hits	289	Target Neighborhood Hits	407	Shared Neighborhood Hits	160
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRRC7_HUMAN
θ value	6.43352e-06 (rank : 45)	NC score	0.249150 (rank : 135)
Query Neighborhood Hits	289	Target Neighborhood Hits	423	Shared Neighborhood Hits	117
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	6.43352e-06 (rank : 46)	NC score	0.247698 (rank : 137)
Query Neighborhood Hits	289	Target Neighborhood Hits	416	Shared Neighborhood Hits	113
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP6_HUMAN
θ value	6.43352e-06 (rank : 47)	NC score	0.443551 (rank : 78)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

PDZD2_HUMAN
θ value	8.40245e-06 (rank : 48)	NC score	0.539887 (rank : 32)
Query Neighborhood Hits	289	Target Neighborhood Hits	772	Shared Neighborhood Hits	191
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SNTB1_HUMAN
θ value	8.40245e-06 (rank : 49)	NC score	0.480000 (rank : 63)
Query Neighborhood Hits	289	Target Neighborhood Hits	157	Shared Neighborhood Hits	133
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	8.40245e-06 (rank : 50)	NC score	0.479209 (rank : 64)
Query Neighborhood Hits	289	Target Neighborhood Hits	160	Shared Neighborhood Hits	131
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

EM55_MOUSE
θ value	1.09739e-05 (rank : 51)	NC score	0.463602 (rank : 69)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	115
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NEB2_HUMAN
θ value	2.44474e-05 (rank : 52)	NC score	0.336878 (rank : 105)
Query Neighborhood Hits	289	Target Neighborhood Hits	883	Shared Neighborhood Hits	131
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	2.44474e-05 (rank : 53)	NC score	0.333531 (rank : 109)
Query Neighborhood Hits	289	Target Neighborhood Hits	889	Shared Neighborhood Hits	131
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

LNX1_MOUSE
θ value	4.1701e-05 (rank : 54)	NC score	0.520212 (rank : 42)
Query Neighborhood Hits	289	Target Neighborhood Hits	377	Shared Neighborhood Hits	160
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

NEB1_HUMAN
θ value	4.1701e-05 (rank : 55)	NC score	0.348904 (rank : 100)
Query Neighborhood Hits	289	Target Neighborhood Hits	829	Shared Neighborhood Hits	145
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

CSKP_HUMAN
θ value	5.44631e-05 (rank : 56)	NC score	0.155661 (rank : 171)
Query Neighborhood Hits	289	Target Neighborhood Hits	1022	Shared Neighborhood Hits	110
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

PDZ11_MOUSE
θ value	5.44631e-05 (rank : 57)	NC score	0.583886 (rank : 18)
Query Neighborhood Hits	289	Target Neighborhood Hits	154	Shared Neighborhood Hits	127
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD1_MOUSE
θ value	5.44631e-05 (rank : 58)	NC score	0.494292 (rank : 57)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	144
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LNX2_HUMAN
θ value	7.1131e-05 (rank : 59)	NC score	0.508858 (rank : 48)
Query Neighborhood Hits	289	Target Neighborhood Hits	389	Shared Neighborhood Hits	160
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PDZ11_HUMAN
θ value	7.1131e-05 (rank : 60)	NC score	0.583209 (rank : 19)
Query Neighborhood Hits	289	Target Neighborhood Hits	160	Shared Neighborhood Hits	130
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MAGI2_HUMAN
θ value	9.29e-05 (rank : 61)	NC score	0.483154 (rank : 62)
Query Neighborhood Hits	289	Target Neighborhood Hits	373	Shared Neighborhood Hits	183
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	9.29e-05 (rank : 62)	NC score	0.488538 (rank : 60)
Query Neighborhood Hits	289	Target Neighborhood Hits	370	Shared Neighborhood Hits	180
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PARD3_HUMAN
θ value	9.29e-05 (rank : 63)	NC score	0.509586 (rank : 47)
Query Neighborhood Hits	289	Target Neighborhood Hits	312	Shared Neighborhood Hits	158
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

ARHGB_HUMAN
θ value	0.000121331 (rank : 64)	NC score	0.266801 (rank : 125)
Query Neighborhood Hits	289	Target Neighborhood Hits	375	Shared Neighborhood Hits	146
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

MPP6_MOUSE
θ value	0.000121331 (rank : 65)	NC score	0.437248 (rank : 80)
Query Neighborhood Hits	289	Target Neighborhood Hits	187	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

GRIP2_HUMAN
θ value	0.000158464 (rank : 66)	NC score	0.546087 (rank : 29)
Query Neighborhood Hits	289	Target Neighborhood Hits	256	Shared Neighborhood Hits	169
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

PDZD1_HUMAN
θ value	0.000158464 (rank : 67)	NC score	0.486438 (rank : 61)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	139
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

CAR10_MOUSE
θ value	0.00020696 (rank : 68)	NC score	0.222871 (rank : 147)
Query Neighborhood Hits	289	Target Neighborhood Hits	407	Shared Neighborhood Hits	27
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

MAGI1_HUMAN
θ value	0.00020696 (rank : 69)	NC score	0.504668 (rank : 51)
Query Neighborhood Hits	289	Target Neighborhood Hits	388	Shared Neighborhood Hits	187
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

SNTG2_HUMAN
θ value	0.00020696 (rank : 70)	NC score	0.503702 (rank : 53)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

LNX1_HUMAN
θ value	0.000270298 (rank : 71)	NC score	0.514930 (rank : 46)
Query Neighborhood Hits	289	Target Neighborhood Hits	379	Shared Neighborhood Hits	150
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MPP3_MOUSE
θ value	0.000270298 (rank : 72)	NC score	0.464933 (rank : 68)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PZRN4_HUMAN
θ value	0.000270298 (rank : 73)	NC score	0.453724 (rank : 75)
Query Neighborhood Hits	289	Target Neighborhood Hits	438	Shared Neighborhood Hits	144
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

CAR10_HUMAN
θ value	0.00035302 (rank : 74)	NC score	0.183526 (rank : 157)
Query Neighborhood Hits	289	Target Neighborhood Hits	569	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

PARD3_MOUSE
θ value	0.000461057 (rank : 75)	NC score	0.502893 (rank : 54)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	155
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PZRN3_HUMAN
θ value	0.000602161 (rank : 76)	NC score	0.453599 (rank : 76)
Query Neighborhood Hits	289	Target Neighborhood Hits	461	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.000602161 (rank : 77)	NC score	0.451656 (rank : 77)
Query Neighborhood Hits	289	Target Neighborhood Hits	447	Shared Neighborhood Hits	146
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RPGF6_HUMAN
θ value	0.000602161 (rank : 78)	NC score	0.330562 (rank : 111)
Query Neighborhood Hits	289	Target Neighborhood Hits	266	Shared Neighborhood Hits	146
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

EM55_HUMAN
θ value	0.000786445 (rank : 79)	NC score	0.453962 (rank : 74)
Query Neighborhood Hits	289	Target Neighborhood Hits	228	Shared Neighborhood Hits	116
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

MAGI1_MOUSE
θ value	0.00102713 (rank : 80)	NC score	0.497712 (rank : 55)
Query Neighborhood Hits	289	Target Neighborhood Hits	403	Shared Neighborhood Hits	191
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PDZD7_HUMAN
θ value	0.00102713 (rank : 81)	NC score	0.544512 (rank : 30)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	152
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PAR3L_HUMAN
θ value	0.00175202 (rank : 82)	NC score	0.515651 (rank : 45)
Query Neighborhood Hits	289	Target Neighborhood Hits	297	Shared Neighborhood Hits	148
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDLI2_HUMAN
θ value	0.00228821 (rank : 83)	NC score	0.300173 (rank : 113)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

RPGF2_HUMAN
θ value	0.00228821 (rank : 84)	NC score	0.286362 (rank : 116)
Query Neighborhood Hits	289	Target Neighborhood Hits	242	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

CSKP_MOUSE
θ value	0.00298849 (rank : 85)	NC score	0.144203 (rank : 175)
Query Neighborhood Hits	289	Target Neighborhood Hits	1027	Shared Neighborhood Hits	111
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

MPP3_HUMAN
θ value	0.00298849 (rank : 86)	NC score	0.469287 (rank : 67)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

SNTG1_MOUSE
θ value	0.00298849 (rank : 87)	NC score	0.455314 (rank : 72)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

K1849_MOUSE
θ value	0.00390308 (rank : 88)	NC score	0.380101 (rank : 91)
Query Neighborhood Hits	289	Target Neighborhood Hits	335	Shared Neighborhood Hits	140
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTG1_HUMAN
θ value	0.00390308 (rank : 89)	NC score	0.455640 (rank : 71)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG2_MOUSE
θ value	0.00390308 (rank : 90)	NC score	0.475993 (rank : 65)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

K1849_HUMAN
θ value	0.00509761 (rank : 91)	NC score	0.382060 (rank : 90)
Query Neighborhood Hits	289	Target Neighborhood Hits	220	Shared Neighborhood Hits	132
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

RHPN1_MOUSE
θ value	0.00509761 (rank : 92)	NC score	0.268867 (rank : 123)
Query Neighborhood Hits	289	Target Neighborhood Hits	154	Shared Neighborhood Hits	116
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

ARHGC_MOUSE
θ value	0.00665767 (rank : 93)	NC score	0.245510 (rank : 139)
Query Neighborhood Hits	289	Target Neighborhood Hits	344	Shared Neighborhood Hits	139
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LIN7C_HUMAN
θ value	0.00665767 (rank : 94)	NC score	0.530741 (rank : 33)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.00665767 (rank : 95)	NC score	0.530741 (rank : 34)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	164
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PDZD3_HUMAN
θ value	0.00665767 (rank : 96)	NC score	0.443040 (rank : 79)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	143
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

NOS1_HUMAN
θ value	0.00869519 (rank : 97)	NC score	0.235206 (rank : 144)
Query Neighborhood Hits	289	Target Neighborhood Hits	218	Shared Neighborhood Hits	134
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PTN4_HUMAN
θ value	0.00869519 (rank : 98)	NC score	0.138427 (rank : 176)
Query Neighborhood Hits	289	Target Neighborhood Hits	303	Shared Neighborhood Hits	110
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

USH1C_MOUSE
θ value	0.00869519 (rank : 99)	NC score	0.506963 (rank : 49)
Query Neighborhood Hits	289	Target Neighborhood Hits	557	Shared Neighborhood Hits	178
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

NBN_MOUSE
θ value	0.0113563 (rank : 100)	NC score	0.058645 (rank : 212)
Query Neighborhood Hits	289	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

ARHGC_HUMAN
θ value	0.0148317 (rank : 101)	NC score	0.249513 (rank : 134)
Query Neighborhood Hits	289	Target Neighborhood Hits	351	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PDLI2_MOUSE
θ value	0.0148317 (rank : 102)	NC score	0.275782 (rank : 119)
Query Neighborhood Hits	289	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

USH1C_HUMAN
θ value	0.0148317 (rank : 103)	NC score	0.551594 (rank : 26)
Query Neighborhood Hits	289	Target Neighborhood Hits	327	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

AFAD_HUMAN
θ value	0.0252991 (rank : 104)	NC score	0.347022 (rank : 102)
Query Neighborhood Hits	289	Target Neighborhood Hits	689	Shared Neighborhood Hits	145
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DVL2_HUMAN
θ value	0.0252991 (rank : 105)	NC score	0.336579 (rank : 107)
Query Neighborhood Hits	289	Target Neighborhood Hits	223	Shared Neighborhood Hits	110
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0.0252991 (rank : 106)	NC score	0.335824 (rank : 108)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	112
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	0.0252991 (rank : 107)	NC score	0.351952 (rank : 98)
Query Neighborhood Hits	289	Target Neighborhood Hits	194	Shared Neighborhood Hits	109
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.0252991 (rank : 108)	NC score	0.352913 (rank : 95)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

LIN7B_HUMAN
θ value	0.0252991 (rank : 109)	NC score	0.530110 (rank : 36)
Query Neighborhood Hits	289	Target Neighborhood Hits	200	Shared Neighborhood Hits	166
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

NPBL_MOUSE
θ value	0.0252991 (rank : 110)	NC score	0.048895 (rank : 233)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	70
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PDZD3_MOUSE
θ value	0.0252991 (rank : 111)	NC score	0.397148 (rank : 89)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	140
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

LIN7B_MOUSE
θ value	0.0330416 (rank : 112)	NC score	0.527319 (rank : 38)
Query Neighborhood Hits	289	Target Neighborhood Hits	200	Shared Neighborhood Hits	166
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PCLO_MOUSE
θ value	0.0330416 (rank : 113)	NC score	0.164582 (rank : 167)
Query Neighborhood Hits	289	Target Neighborhood Hits	2275	Shared Neighborhood Hits	180
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TGON2_HUMAN
θ value	0.0330416 (rank : 114)	NC score	0.054691 (rank : 221)
Query Neighborhood Hits	289	Target Neighborhood Hits	1037	Shared Neighborhood Hits	67
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

C8AP2_MOUSE
θ value	0.0431538 (rank : 115)	NC score	0.037320 (rank : 255)
Query Neighborhood Hits	289	Target Neighborhood Hits	405	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

PDZK4_MOUSE
θ value	0.0431538 (rank : 116)	NC score	0.352655 (rank : 96)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PTN3_HUMAN
θ value	0.0431538 (rank : 117)	NC score	0.121942 (rank : 183)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	105
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

DVL1_HUMAN
θ value	0.0563607 (rank : 118)	NC score	0.348186 (rank : 101)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	110
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	0.0563607 (rank : 119)	NC score	0.343842 (rank : 103)
Query Neighborhood Hits	289	Target Neighborhood Hits	146	Shared Neighborhood Hits	108
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PDZK4_HUMAN
θ value	0.0563607 (rank : 120)	NC score	0.354721 (rank : 94)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SDCB1_HUMAN
θ value	0.0563607 (rank : 121)	NC score	0.350743 (rank : 99)
Query Neighborhood Hits	289	Target Neighborhood Hits	150	Shared Neighborhood Hits	126
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	0.0563607 (rank : 122)	NC score	0.352619 (rank : 97)
Query Neighborhood Hits	289	Target Neighborhood Hits	144	Shared Neighborhood Hits	124
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SYNP2_HUMAN
θ value	0.0563607 (rank : 123)	NC score	0.165536 (rank : 166)
Query Neighborhood Hits	289	Target Neighborhood Hits	323	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TX1B3_HUMAN
θ value	0.0563607 (rank : 124)	NC score	0.527393 (rank : 37)
Query Neighborhood Hits	289	Target Neighborhood Hits	161	Shared Neighborhood Hits	142
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.0563607 (rank : 125)	NC score	0.524406 (rank : 40)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	139
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

APBA3_MOUSE
θ value	0.0736092 (rank : 126)	NC score	0.290823 (rank : 114)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	121
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

DVL1L_HUMAN
θ value	0.0736092 (rank : 127)	NC score	0.337208 (rank : 104)
Query Neighborhood Hits	289	Target Neighborhood Hits	146	Shared Neighborhood Hits	107
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

LIMK1_HUMAN
θ value	0.0736092 (rank : 128)	NC score	0.029459 (rank : 267)
Query Neighborhood Hits	289	Target Neighborhood Hits	1005	Shared Neighborhood Hits	74
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

NACAM_MOUSE
θ value	0.0736092 (rank : 129)	NC score	0.044819 (rank : 237)
Query Neighborhood Hits	289	Target Neighborhood Hits	1866	Shared Neighborhood Hits	96
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SETX_HUMAN
θ value	0.0736092 (rank : 130)	NC score	0.044895 (rank : 236)
Query Neighborhood Hits	289	Target Neighborhood Hits	368	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

APBA1_HUMAN
θ value	0.0961366 (rank : 131)	NC score	0.305333 (rank : 112)
Query Neighborhood Hits	289	Target Neighborhood Hits	325	Shared Neighborhood Hits	142
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CASC3_MOUSE
θ value	0.0961366 (rank : 132)	NC score	0.044454 (rank : 238)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

IL16_HUMAN
θ value	0.0961366 (rank : 133)	NC score	0.496745 (rank : 56)
Query Neighborhood Hits	289	Target Neighborhood Hits	207	Shared Neighborhood Hits	138
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LIMK2_MOUSE
θ value	0.0961366 (rank : 134)	NC score	0.035530 (rank : 257)
Query Neighborhood Hits	289	Target Neighborhood Hits	998	Shared Neighborhood Hits	62
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PEG3_MOUSE
θ value	0.0961366 (rank : 135)	NC score	0.006695 (rank : 334)
Query Neighborhood Hits	289	Target Neighborhood Hits	1101	Shared Neighborhood Hits	31
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RHPN1_HUMAN
θ value	0.0961366 (rank : 136)	NC score	0.245580 (rank : 138)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	111
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

ADDB_MOUSE
θ value	0.125558 (rank : 137)	NC score	0.026587 (rank : 277)
Query Neighborhood Hits	289	Target Neighborhood Hits	574	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

K1543_MOUSE
θ value	0.125558 (rank : 138)	NC score	0.049300 (rank : 232)
Query Neighborhood Hits	289	Target Neighborhood Hits	497	Shared Neighborhood Hits	49
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LIMK2_HUMAN
θ value	0.125558 (rank : 139)	NC score	0.033079 (rank : 261)
Query Neighborhood Hits	289	Target Neighborhood Hits	986	Shared Neighborhood Hits	63
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIPB2_HUMAN
θ value	0.125558 (rank : 140)	NC score	0.032917 (rank : 262)
Query Neighborhood Hits	289	Target Neighborhood Hits	599	Shared Neighborhood Hits	28
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

NHRF2_MOUSE
θ value	0.125558 (rank : 141)	NC score	0.406708 (rank : 85)
Query Neighborhood Hits	289	Target Neighborhood Hits	194	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

LIN7A_HUMAN
θ value	0.163984 (rank : 142)	NC score	0.518623 (rank : 43)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.163984 (rank : 143)	NC score	0.518510 (rank : 44)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

MAST3_HUMAN
θ value	0.163984 (rank : 144)	NC score	0.040759 (rank : 244)
Query Neighborhood Hits	289	Target Neighborhood Hits	1128	Shared Neighborhood Hits	121
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

NHRF2_HUMAN
θ value	0.163984 (rank : 145)	NC score	0.419434 (rank : 83)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	151
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

RIMS2_MOUSE
θ value	0.163984 (rank : 146)	NC score	0.167641 (rank : 163)
Query Neighborhood Hits	289	Target Neighborhood Hits	376	Shared Neighborhood Hits	108
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ELOA1_MOUSE
θ value	0.21417 (rank : 147)	NC score	0.039507 (rank : 247)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

LIMK1_MOUSE
θ value	0.21417 (rank : 148)	NC score	0.027306 (rank : 274)
Query Neighborhood Hits	289	Target Neighborhood Hits	1008	Shared Neighborhood Hits	76
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

PRAX_HUMAN
θ value	0.21417 (rank : 149)	NC score	0.146523 (rank : 173)
Query Neighborhood Hits	289	Target Neighborhood Hits	215	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

TARA_HUMAN
θ value	0.21417 (rank : 150)	NC score	0.046113 (rank : 234)
Query Neighborhood Hits	289	Target Neighborhood Hits	1626	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TXND2_MOUSE
θ value	0.21417 (rank : 151)	NC score	0.032357 (rank : 265)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ATBF1_HUMAN
θ value	0.279714 (rank : 152)	NC score	0.013066 (rank : 320)
Query Neighborhood Hits	289	Target Neighborhood Hits	1547	Shared Neighborhood Hits	47
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

HTRA3_MOUSE
θ value	0.279714 (rank : 153)	NC score	0.099310 (rank : 189)
Query Neighborhood Hits	289	Target Neighborhood Hits	156	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

IL16_MOUSE
θ value	0.279714 (rank : 154)	NC score	0.475301 (rank : 66)
Query Neighborhood Hits	289	Target Neighborhood Hits	189	Shared Neighborhood Hits	138
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

K0562_MOUSE
θ value	0.279714 (rank : 155)	NC score	0.028152 (rank : 271)
Query Neighborhood Hits	289	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

NHERF_HUMAN
θ value	0.279714 (rank : 156)	NC score	0.418158 (rank : 84)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	141
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
θ value	0.279714 (rank : 157)	NC score	0.435881 (rank : 81)
Query Neighborhood Hits	289	Target Neighborhood Hits	195	Shared Neighborhood Hits	142
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

DDX10_HUMAN
θ value	0.365318 (rank : 158)	NC score	0.007486 (rank : 329)
Query Neighborhood Hits	289	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

GIPC1_HUMAN
θ value	0.365318 (rank : 159)	NC score	0.158075 (rank : 170)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	81
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

NFH_MOUSE
θ value	0.365318 (rank : 160)	NC score	0.033843 (rank : 260)
Query Neighborhood Hits	289	Target Neighborhood Hits	2247	Shared Neighborhood Hits	106
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRAX_MOUSE
θ value	0.365318 (rank : 161)	NC score	0.168341 (rank : 161)
Query Neighborhood Hits	289	Target Neighborhood Hits	199	Shared Neighborhood Hits	49
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

RIMS1_HUMAN
θ value	0.365318 (rank : 162)	NC score	0.186191 (rank : 155)
Query Neighborhood Hits	289	Target Neighborhood Hits	437	Shared Neighborhood Hits	134
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

MAST2_HUMAN
θ value	0.47712 (rank : 163)	NC score	0.045273 (rank : 235)
Query Neighborhood Hits	289	Target Neighborhood Hits	1189	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST4_HUMAN
θ value	0.47712 (rank : 164)	NC score	0.050218 (rank : 230)
Query Neighborhood Hits	289	Target Neighborhood Hits	1804	Shared Neighborhood Hits	155
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PDLI4_MOUSE
θ value	0.47712 (rank : 165)	NC score	0.186772 (rank : 154)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RECQ5_HUMAN
θ value	0.47712 (rank : 166)	NC score	0.025589 (rank : 279)
Query Neighborhood Hits	289	Target Neighborhood Hits	390	Shared Neighborhood Hits	32
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SF3B1_HUMAN
θ value	0.47712 (rank : 167)	NC score	0.037326 (rank : 254)
Query Neighborhood Hits	289	Target Neighborhood Hits	341	Shared Neighborhood Hits	24
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.47712 (rank : 168)	NC score	0.037229 (rank : 256)
Query Neighborhood Hits	289	Target Neighborhood Hits	352	Shared Neighborhood Hits	23
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

WDFY3_HUMAN
θ value	0.47712 (rank : 169)	NC score	0.009344 (rank : 325)
Query Neighborhood Hits	289	Target Neighborhood Hits	348	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

E41LA_HUMAN
θ value	0.62314 (rank : 170)	NC score	0.039506 (rank : 248)
Query Neighborhood Hits	289	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

ETV6_HUMAN
θ value	0.62314 (rank : 171)	NC score	0.014013 (rank : 316)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

IWS1_MOUSE
θ value	0.62314 (rank : 172)	NC score	0.051845 (rank : 226)
Query Neighborhood Hits	289	Target Neighborhood Hits	1258	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NELFE_HUMAN
θ value	0.62314 (rank : 173)	NC score	0.026668 (rank : 276)
Query Neighborhood Hits	289	Target Neighborhood Hits	107	Shared Neighborhood Hits	10
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

PDLI7_HUMAN
θ value	0.62314 (rank : 174)	NC score	0.124513 (rank : 182)
Query Neighborhood Hits	289	Target Neighborhood Hits	547	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GIPC1_MOUSE
θ value	0.813845 (rank : 175)	NC score	0.162725 (rank : 168)
Query Neighborhood Hits	289	Target Neighborhood Hits	92	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

GLI1_HUMAN
θ value	0.813845 (rank : 176)	NC score	-0.004048 (rank : 344)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	14
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

MBB1A_HUMAN
θ value	0.813845 (rank : 177)	NC score	0.041017 (rank : 243)
Query Neighborhood Hits	289	Target Neighborhood Hits	665	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MPP4_HUMAN
θ value	0.813845 (rank : 178)	NC score	0.427273 (rank : 82)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	127
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

SDCB2_HUMAN
θ value	0.813845 (rank : 179)	NC score	0.277110 (rank : 118)
Query Neighborhood Hits	289	Target Neighborhood Hits	121	Shared Neighborhood Hits	109
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SHAN1_HUMAN
θ value	0.813845 (rank : 180)	NC score	0.118054 (rank : 185)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	0.813845 (rank : 181)	NC score	0.190827 (rank : 153)
Query Neighborhood Hits	289	Target Neighborhood Hits	346	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

BOP1_HUMAN
θ value	1.06291 (rank : 182)	NC score	0.018101 (rank : 303)
Query Neighborhood Hits	289	Target Neighborhood Hits	257	Shared Neighborhood Hits	5
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

CCD55_MOUSE
θ value	1.06291 (rank : 183)	NC score	0.032828 (rank : 263)
Query Neighborhood Hits	289	Target Neighborhood Hits	519	Shared Neighborhood Hits	38
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CSF1_HUMAN
θ value	1.06291 (rank : 184)	NC score	0.025288 (rank : 280)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

ELOA1_HUMAN
θ value	1.06291 (rank : 185)	NC score	0.032570 (rank : 264)
Query Neighborhood Hits	289	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

IWS1_HUMAN
θ value	1.06291 (rank : 186)	NC score	0.053643 (rank : 224)
Query Neighborhood Hits	289	Target Neighborhood Hits	1241	Shared Neighborhood Hits	78
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MLF2_MOUSE
θ value	1.06291 (rank : 187)	NC score	0.020536 (rank : 296)
Query Neighborhood Hits	289	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KX1	Gene names	Mlf2
Domain Architecture	No domain graphic available
Description	Myeloid leukemia factor 2 (Myelodysplasia-myeloid leukemia factor 2).

SDCB2_MOUSE
θ value	1.06291 (rank : 188)	NC score	0.287055 (rank : 115)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	102
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SETD2_HUMAN
θ value	1.06291 (rank : 189)	NC score	0.028099 (rank : 272)
Query Neighborhood Hits	289	Target Neighborhood Hits	412	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SYP2L_HUMAN
θ value	1.06291 (rank : 190)	NC score	0.250305 (rank : 133)
Query Neighborhood Hits	289	Target Neighborhood Hits	400	Shared Neighborhood Hits	125
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CMTA1_HUMAN
θ value	1.38821 (rank : 191)	NC score	0.022813 (rank : 290)
Query Neighborhood Hits	289	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

LYSM2_MOUSE
θ value	1.38821 (rank : 192)	NC score	0.026343 (rank : 278)
Query Neighborhood Hits	289	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7V2, Q80ZR2	Gene names	Lysmd2
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 2.

MAST2_MOUSE
θ value	1.38821 (rank : 193)	NC score	0.043097 (rank : 239)
Query Neighborhood Hits	289	Target Neighborhood Hits	1110	Shared Neighborhood Hits	119
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIMS2_HUMAN
θ value	1.38821 (rank : 194)	NC score	0.166621 (rank : 164)
Query Neighborhood Hits	289	Target Neighborhood Hits	342	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RSF1_HUMAN
θ value	1.38821 (rank : 195)	NC score	0.028393 (rank : 270)
Query Neighborhood Hits	289	Target Neighborhood Hits	539	Shared Neighborhood Hits	31
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SHAN2_MOUSE
θ value	1.38821 (rank : 196)	NC score	0.165666 (rank : 165)
Query Neighborhood Hits	289	Target Neighborhood Hits	446	Shared Neighborhood Hits	118
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STXB4_HUMAN
θ value	1.38821 (rank : 197)	NC score	0.274560 (rank : 120)
Query Neighborhood Hits	289	Target Neighborhood Hits	616	Shared Neighborhood Hits	106
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TARA_MOUSE
θ value	1.38821 (rank : 198)	NC score	0.041156 (rank : 241)
Query Neighborhood Hits	289	Target Neighborhood Hits	1133	Shared Neighborhood Hits	69
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AN32A_HUMAN
θ value	1.81305 (rank : 199)	NC score	0.024474 (rank : 285)
Query Neighborhood Hits	289	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

CD008_HUMAN
θ value	1.81305 (rank : 200)	NC score	0.024726 (rank : 283)
Query Neighborhood Hits	289	Target Neighborhood Hits	330	Shared Neighborhood Hits	18
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CD248_MOUSE
θ value	1.81305 (rank : 201)	NC score	0.005218 (rank : 340)
Query Neighborhood Hits	289	Target Neighborhood Hits	578	Shared Neighborhood Hits	20
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EFS_HUMAN
θ value	1.81305 (rank : 202)	NC score	0.035377 (rank : 258)
Query Neighborhood Hits	289	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	1.81305 (rank : 203)	NC score	0.037831 (rank : 252)
Query Neighborhood Hits	289	Target Neighborhood Hits	389	Shared Neighborhood Hits	28
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

GOGB1_HUMAN
θ value	1.81305 (rank : 204)	NC score	0.020929 (rank : 295)
Query Neighborhood Hits	289	Target Neighborhood Hits	2297	Shared Neighborhood Hits	75
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HCLS1_MOUSE
θ value	1.81305 (rank : 205)	NC score	0.017381 (rank : 305)
Query Neighborhood Hits	289	Target Neighborhood Hits	329	Shared Neighborhood Hits	22
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

MAP9_MOUSE
θ value	1.81305 (rank : 206)	NC score	0.017367 (rank : 306)
Query Neighborhood Hits	289	Target Neighborhood Hits	529	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SCG3_HUMAN
θ value	1.81305 (rank : 207)	NC score	0.018974 (rank : 300)
Query Neighborhood Hits	289	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXD2, Q96C83, Q96GE8, Q9Y6G7	Gene names	SCG3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

WWP2_HUMAN
θ value	1.81305 (rank : 208)	NC score	0.022086 (rank : 293)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

CI079_HUMAN
θ value	2.36792 (rank : 209)	NC score	0.027395 (rank : 273)
Query Neighborhood Hits	289	Target Neighborhood Hits	288	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CNGB1_HUMAN
θ value	2.36792 (rank : 210)	NC score	0.011344 (rank : 322)
Query Neighborhood Hits	289	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

LIPA1_HUMAN
θ value	2.36792 (rank : 211)	NC score	0.019085 (rank : 299)
Query Neighborhood Hits	289	Target Neighborhood Hits	1294	Shared Neighborhood Hits	52
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPB2_MOUSE
θ value	2.36792 (rank : 212)	NC score	0.025105 (rank : 281)
Query Neighborhood Hits	289	Target Neighborhood Hits	570	Shared Neighborhood Hits	28
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LMO7_HUMAN
θ value	2.36792 (rank : 213)	NC score	0.127160 (rank : 180)
Query Neighborhood Hits	289	Target Neighborhood Hits	507	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

M4K4_MOUSE
θ value	2.36792 (rank : 214)	NC score	0.007704 (rank : 328)
Query Neighborhood Hits	289	Target Neighborhood Hits	1560	Shared Neighborhood Hits	53
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAST1_HUMAN
θ value	2.36792 (rank : 215)	NC score	0.038764 (rank : 250)
Query Neighborhood Hits	289	Target Neighborhood Hits	1146	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	2.36792 (rank : 216)	NC score	0.039164 (rank : 249)
Query Neighborhood Hits	289	Target Neighborhood Hits	1123	Shared Neighborhood Hits	121
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MLL3_HUMAN
θ value	2.36792 (rank : 217)	NC score	0.023735 (rank : 288)
Query Neighborhood Hits	289	Target Neighborhood Hits	1644	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AP3B2_HUMAN
θ value	3.0926 (rank : 218)	NC score	0.013257 (rank : 318)
Query Neighborhood Hits	289	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

DMD_MOUSE
θ value	3.0926 (rank : 219)	NC score	0.006820 (rank : 332)
Query Neighborhood Hits	289	Target Neighborhood Hits	1111	Shared Neighborhood Hits	36
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

FOSL1_HUMAN
θ value	3.0926 (rank : 220)	NC score	0.010822 (rank : 323)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOXL1_MOUSE
θ value	3.0926 (rank : 221)	NC score	0.002059 (rank : 342)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

GIT2_HUMAN
θ value	3.0926 (rank : 222)	NC score	0.004445 (rank : 341)
Query Neighborhood Hits	289	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

PDLI3_HUMAN
θ value	3.0926 (rank : 223)	NC score	0.183067 (rank : 158)
Query Neighborhood Hits	289	Target Neighborhood Hits	199	Shared Neighborhood Hits	96
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SRRM2_MOUSE
θ value	3.0926 (rank : 224)	NC score	0.055325 (rank : 220)
Query Neighborhood Hits	289	Target Neighborhood Hits	1470	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYTL2_HUMAN
θ value	3.0926 (rank : 225)	NC score	0.013112 (rank : 319)
Query Neighborhood Hits	289	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CBP_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.022182 (rank : 292)
Query Neighborhood Hits	289	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NIPBL_HUMAN
θ value	4.03905 (rank : 227)	NC score	0.041070 (rank : 242)
Query Neighborhood Hits	289	Target Neighborhood Hits	1311	Shared Neighborhood Hits	82
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PAR6G_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.255495 (rank : 131)
Query Neighborhood Hits	289	Target Neighborhood Hits	159	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	4.03905 (rank : 229)	NC score	0.253884 (rank : 132)
Query Neighborhood Hits	289	Target Neighborhood Hits	121	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDLI3_MOUSE
θ value	4.03905 (rank : 230)	NC score	0.168096 (rank : 162)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

RB15B_HUMAN
θ value	4.03905 (rank : 231)	NC score	0.015501 (rank : 313)
Query Neighborhood Hits	289	Target Neighborhood Hits	251	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

RBM16_HUMAN
θ value	4.03905 (rank : 232)	NC score	0.016218 (rank : 308)
Query Neighborhood Hits	289	Target Neighborhood Hits	300	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RGS12_HUMAN
θ value	4.03905 (rank : 233)	NC score	0.205722 (rank : 149)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	128
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RUSC1_HUMAN
θ value	4.03905 (rank : 234)	NC score	0.022403 (rank : 291)
Query Neighborhood Hits	289	Target Neighborhood Hits	226	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SNIP_MOUSE
θ value	4.03905 (rank : 235)	NC score	0.017817 (rank : 304)
Query Neighborhood Hits	289	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SRRM2_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.057117 (rank : 214)
Query Neighborhood Hits	289	Target Neighborhood Hits	1296	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

AFF3_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.018556 (rank : 301)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

BAT2_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.039757 (rank : 246)
Query Neighborhood Hits	289	Target Neighborhood Hits	931	Shared Neighborhood Hits	67
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	5.27518 (rank : 239)	NC score	0.037413 (rank : 253)
Query Neighborhood Hits	289	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABIN_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.024805 (rank : 282)
Query Neighborhood Hits	289	Target Neighborhood Hits	490	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCD55_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.034417 (rank : 259)
Query Neighborhood Hits	289	Target Neighborhood Hits	513	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CNKR2_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.077078 (rank : 193)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.077157 (rank : 192)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CO039_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.018396 (rank : 302)
Query Neighborhood Hits	289	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CYLC1_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.028619 (rank : 269)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

E41LB_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.030874 (rank : 266)
Query Neighborhood Hits	289	Target Neighborhood Hits	59	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

HTRA4_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.040613 (rank : 245)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	36
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

LIPS_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.023145 (rank : 289)
Query Neighborhood Hits	289	Target Neighborhood Hits	314	Shared Neighborhood Hits	33
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MYO9B_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.006353 (rank : 338)
Query Neighborhood Hits	289	Target Neighborhood Hits	641	Shared Neighborhood Hits	46
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYST3_HUMAN
θ value	5.27518 (rank : 250)	NC score	0.014621 (rank : 315)
Query Neighborhood Hits	289	Target Neighborhood Hits	772	Shared Neighborhood Hits	43
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PAR6B_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.262162 (rank : 129)
Query Neighborhood Hits	289	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	5.27518 (rank : 252)	NC score	0.264114 (rank : 128)
Query Neighborhood Hits	289	Target Neighborhood Hits	128	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PDLI5_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.135637 (rank : 177)
Query Neighborhood Hits	289	Target Neighborhood Hits	322	Shared Neighborhood Hits	109
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDZD8_HUMAN
θ value	5.27518 (rank : 254)	NC score	0.115446 (rank : 186)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

RBBP6_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.042066 (rank : 240)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SET1A_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.037994 (rank : 251)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ST5_HUMAN
θ value	5.27518 (rank : 257)	NC score	0.006817 (rank : 333)
Query Neighborhood Hits	289	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

AKAP2_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.013709 (rank : 317)
Query Neighborhood Hits	289	Target Neighborhood Hits	507	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

CAC1A_MOUSE
θ value	6.88961 (rank : 259)	NC score	0.007776 (rank : 327)
Query Neighborhood Hits	289	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CCNL1_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.015352 (rank : 314)
Query Neighborhood Hits	289	Target Neighborhood Hits	79	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

HES1_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.005351 (rank : 339)
Query Neighborhood Hits	289	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HTRA3_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.086482 (rank : 190)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

MKL1_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.007933 (rank : 326)
Query Neighborhood Hits	289	Target Neighborhood Hits	232	Shared Neighborhood Hits	15
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MYLK_MOUSE
θ value	6.88961 (rank : 264)	NC score	0.001637 (rank : 343)
Query Neighborhood Hits	289	Target Neighborhood Hits	1489	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PCQAP_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.023817 (rank : 287)
Query Neighborhood Hits	289	Target Neighborhood Hits	549	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.020219 (rank : 298)
Query Neighborhood Hits	289	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PHLB1_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.016845 (rank : 307)
Query Neighborhood Hits	289	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PTN14_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.024708 (rank : 284)
Query Neighborhood Hits	289	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

RBM6_HUMAN
θ value	6.88961 (rank : 269)	NC score	0.010606 (rank : 324)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	15
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RHG06_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.007174 (rank : 331)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	6.88961 (rank : 271)	NC score	0.006529 (rank : 335)
Query Neighborhood Hits	289	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

STXB4_MOUSE
θ value	6.88961 (rank : 272)	NC score	0.261169 (rank : 130)
Query Neighborhood Hits	289	Target Neighborhood Hits	629	Shared Neighborhood Hits	105
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYNP2_MOUSE
θ value	6.88961 (rank : 273)	NC score	0.205643 (rank : 150)
Query Neighborhood Hits	289	Target Neighborhood Hits	252	Shared Neighborhood Hits	120
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYV_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.006394 (rank : 337)
Query Neighborhood Hits	289	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

ASPP1_MOUSE
θ value	8.99809 (rank : 275)	NC score	0.020397 (rank : 297)
Query Neighborhood Hits	289	Target Neighborhood Hits	1244	Shared Neighborhood Hits	58
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAG3_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.026934 (rank : 275)
Query Neighborhood Hits	289	Target Neighborhood Hits	314	Shared Neighborhood Hits	27
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CAC1A_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.006474 (rank : 336)
Query Neighborhood Hits	289	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CIC_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.015709 (rank : 312)
Query Neighborhood Hits	289	Target Neighborhood Hits	992	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DHX37_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.007463 (rank : 330)
Query Neighborhood Hits	289	Target Neighborhood Hits	133	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

GIPC3_MOUSE
θ value	8.99809 (rank : 280)	NC score	0.074859 (rank : 196)
Query Neighborhood Hits	289	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

IF3A_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.016113 (rank : 309)
Query Neighborhood Hits	289	Target Neighborhood Hits	875	Shared Neighborhood Hits	38
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

NCOR1_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.012372 (rank : 321)
Query Neighborhood Hits	289	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

RGNEF_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.023933 (rank : 286)
Query Neighborhood Hits	289	Target Neighborhood Hits	641	Shared Neighborhood Hits	30
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SNIP_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.021642 (rank : 294)
Query Neighborhood Hits	289	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SPT5H_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.015915 (rank : 311)
Query Neighborhood Hits	289	Target Neighborhood Hits	436	Shared Neighborhood Hits	31
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	8.99809 (rank : 286)	NC score	0.015929 (rank : 310)
Query Neighborhood Hits	289	Target Neighborhood Hits	437	Shared Neighborhood Hits	33
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TIAM1_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.070882 (rank : 204)
Query Neighborhood Hits	289	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.054462 (rank : 222)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	51
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

YLPM1_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.029295 (rank : 268)
Query Neighborhood Hits	289	Target Neighborhood Hits	505	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

APBA2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.271301 (rank : 121)
Query Neighborhood Hits	289	Target Neighborhood Hits	220	Shared Neighborhood Hits	136
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.271269 (rank : 122)
Query Neighborhood Hits	289	Target Neighborhood Hits	219	Shared Neighborhood Hits	136
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.265692 (rank : 127)
Query Neighborhood Hits	289	Target Neighborhood Hits	201	Shared Neighborhood Hits	129
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APXL_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.168951 (rank : 160)
Query Neighborhood Hits	289	Target Neighborhood Hits	553	Shared Neighborhood Hits	105
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CACB1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.075518 (rank : 195)
Query Neighborhood Hits	289	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.079106 (rank : 191)
Query Neighborhood Hits	289	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.057142 (rank : 213)
Query Neighborhood Hits	289	Target Neighborhood Hits	99	Shared Neighborhood Hits	26
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.050913 (rank : 229)
Query Neighborhood Hits	289	Target Neighborhood Hits	94	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CACB3_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.071980 (rank : 200)
Query Neighborhood Hits	289	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.071475 (rank : 201)
Query Neighborhood Hits	289	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB4_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.073499 (rank : 197)
Query Neighborhood Hits	289	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB4_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.071353 (rank : 203)
Query Neighborhood Hits	289	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CARD9_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.064440 (rank : 209)
Query Neighborhood Hits	289	Target Neighborhood Hits	602	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CRK_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.072242 (rank : 199)
Query Neighborhood Hits	289	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.071470 (rank : 202)
Query Neighborhood Hits	289	Target Neighborhood Hits	314	Shared Neighborhood Hits	29
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GIPC2_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.121319 (rank : 184)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

GIPC2_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.076190 (rank : 194)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GIPC3_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.072480 (rank : 198)
Query Neighborhood Hits	289	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GRASP_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.226363 (rank : 146)
Query Neighborhood Hits	289	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.222588 (rank : 148)
Query Neighborhood Hits	289	Target Neighborhood Hits	131	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRB2_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.065050 (rank : 208)
Query Neighborhood Hits	289	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.065766 (rank : 207)
Query Neighborhood Hits	289	Target Neighborhood Hits	312	Shared Neighborhood Hits	30
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HTRA1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.051273 (rank : 227)
Query Neighborhood Hits	289	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

KGUA_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.330589 (rank : 110)
Query Neighborhood Hits	289	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.336822 (rank : 106)
Query Neighborhood Hits	289	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LDB3_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.132291 (rank : 179)
Query Neighborhood Hits	289	Target Neighborhood Hits	497	Shared Neighborhood Hits	107
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.133087 (rank : 178)
Query Neighborhood Hits	289	Target Neighborhood Hits	510	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LRRC1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.056040 (rank : 217)
Query Neighborhood Hits	289	Target Neighborhood Hits	282	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.056501 (rank : 216)
Query Neighborhood Hits	289	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

MPP4_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.400691 (rank : 87)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MUC7_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.055484 (rank : 219)
Query Neighborhood Hits	289	Target Neighborhood Hits	538	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MY18A_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.050125 (rank : 231)
Query Neighborhood Hits	289	Target Neighborhood Hits	1989	Shared Neighborhood Hits	169
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NOS1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.183933 (rank : 156)
Query Neighborhood Hits	289	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NPHP1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.052389 (rank : 225)
Query Neighborhood Hits	289	Target Neighborhood Hits	267	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

PAR6A_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.241090 (rank : 143)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.241185 (rank : 142)
Query Neighborhood Hits	289	Target Neighborhood Hits	115	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PDLI1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.147099 (rank : 172)
Query Neighborhood Hits	289	Target Neighborhood Hits	242	Shared Neighborhood Hits	90
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.146462 (rank : 174)
Query Neighborhood Hits	289	Target Neighborhood Hits	213	Shared Neighborhood Hits	93
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.158174 (rank : 169)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	97
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI5_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.126374 (rank : 181)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.102074 (rank : 188)
Query Neighborhood Hits	289	Target Neighborhood Hits	279	Shared Neighborhood Hits	94
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD6_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.111002 (rank : 187)
Query Neighborhood Hits	289	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PICK1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.265942 (rank : 126)
Query Neighborhood Hits	289	Target Neighborhood Hits	132	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.267964 (rank : 124)
Query Neighborhood Hits	289	Target Neighborhood Hits	131	Shared Neighborhood Hits	112
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PSCBP_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.192570 (rank : 152)
Query Neighborhood Hits	289	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSCBP_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.201265 (rank : 151)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	99
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RGS3_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.054053 (rank : 223)
Query Neighborhood Hits	289	Target Neighborhood Hits	1621	Shared Neighborhood Hits	128
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN2_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.051259 (rank : 228)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SRRM1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.070238 (rank : 205)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.060489 (rank : 211)
Query Neighborhood Hits	289	Target Neighborhood Hits	966	Shared Neighborhood Hits	84
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

STAM1_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.055661 (rank : 218)
Query Neighborhood Hits	289	Target Neighborhood Hits	271	Shared Neighborhood Hits	29
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.064038 (rank : 210)
Query Neighborhood Hits	289	Target Neighborhood Hits	273	Shared Neighborhood Hits	30
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.056543 (rank : 215)
Query Neighborhood Hits	289	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SYP2L_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.171986 (rank : 159)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TXND2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.065989 (rank : 206)
Query Neighborhood Hits	289	Target Neighborhood Hits	793	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

Hits sorted by NC score

ZO2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	289
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
NC score	0.986889 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	289	Target Neighborhood Hits	296	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
NC score	0.946385 (rank : 3)	θ value	6.59259e-152 (rank : 5)
Query Neighborhood Hits	289	Target Neighborhood Hits	219	Shared Neighborhood Hits	167
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
NC score	0.942803 (rank : 4)	θ value	8.63019e-144 (rank : 6)
Query Neighborhood Hits	289	Target Neighborhood Hits	224	Shared Neighborhood Hits	171
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO1_MOUSE
NC score	0.915294 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	289	Target Neighborhood Hits	453	Shared Neighborhood Hits	185
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
NC score	0.914099 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	289	Target Neighborhood Hits	474	Shared Neighborhood Hits	183
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DLG2_MOUSE
NC score	0.738097 (rank : 7)	θ value	8.06329e-33 (rank : 7)
Query Neighborhood Hits	289	Target Neighborhood Hits	271	Shared Neighborhood Hits	161
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
NC score	0.737466 (rank : 8)	θ value	1.98606e-31 (rank : 9)
Query Neighborhood Hits	289	Target Neighborhood Hits	279	Shared Neighborhood Hits	163
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG4_MOUSE
NC score	0.736510 (rank : 9)	θ value	1.57365e-28 (rank : 13)
Query Neighborhood Hits	289	Target Neighborhood Hits	282	Shared Neighborhood Hits	167
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.735475 (rank : 10)	θ value	1.2049e-28 (rank : 12)
Query Neighborhood Hits	289	Target Neighborhood Hits	286	Shared Neighborhood Hits	167
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG3_HUMAN
NC score	0.732776 (rank : 11)	θ value	5.40856e-29 (rank : 10)
Query Neighborhood Hits	289	Target Neighborhood Hits	269	Shared Neighborhood Hits	168
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
NC score	0.731529 (rank : 12)	θ value	4.57862e-28 (rank : 14)
Query Neighborhood Hits	289	Target Neighborhood Hits	274	Shared Neighborhood Hits	169
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_MOUSE
NC score	0.730665 (rank : 13)	θ value	1.2049e-28 (rank : 11)
Query Neighborhood Hits	289	Target Neighborhood Hits	285	Shared Neighborhood Hits	159
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG1_HUMAN
NC score	0.728583 (rank : 14)	θ value	5.97985e-28 (rank : 15)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	159
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

SYJ2B_HUMAN
NC score	0.639636 (rank : 15)	θ value	4.92598e-06 (rank : 43)
Query Neighborhood Hits	289	Target Neighborhood Hits	162	Shared Neighborhood Hits	142
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

INADL_MOUSE
NC score	0.607737 (rank : 16)	θ value	3.64472e-09 (rank : 20)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	177
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INADL_HUMAN
NC score	0.593217 (rank : 17)	θ value	8.97725e-08 (rank : 25)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	171
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

PDZ11_MOUSE
NC score	0.583886 (rank : 18)	θ value	5.44631e-05 (rank : 57)
Query Neighborhood Hits	289	Target Neighborhood Hits	154	Shared Neighborhood Hits	127
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_HUMAN
NC score	0.583209 (rank : 19)	θ value	7.1131e-05 (rank : 60)
Query Neighborhood Hits	289	Target Neighborhood Hits	160	Shared Neighborhood Hits	130
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MPDZ_MOUSE
NC score	0.573376 (rank : 20)	θ value	5.81887e-07 (rank : 33)
Query Neighborhood Hits	289	Target Neighborhood Hits	298	Shared Neighborhood Hits	172
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.572367 (rank : 21)	θ value	5.81887e-07 (rank : 32)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	174
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

WHRN_HUMAN
NC score	0.562561 (rank : 22)	θ value	9.92553e-07 (rank : 39)
Query Neighborhood Hits	289	Target Neighborhood Hits	325	Shared Neighborhood Hits	176
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

MPP5_HUMAN
NC score	0.558863 (rank : 23)	θ value	1.2105e-12 (rank : 18)
Query Neighborhood Hits	289	Target Neighborhood Hits	231	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.558499 (rank : 24)	θ value	1.58096e-12 (rank : 19)
Query Neighborhood Hits	289	Target Neighborhood Hits	226	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

WHRN_MOUSE
NC score	0.553074 (rank : 25)	θ value	9.92553e-07 (rank : 40)
Query Neighborhood Hits	289	Target Neighborhood Hits	412	Shared Neighborhood Hits	176
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

USH1C_HUMAN
NC score	0.551594 (rank : 26)	θ value	0.0148317 (rank : 103)
Query Neighborhood Hits	289	Target Neighborhood Hits	327	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

DLG5_HUMAN
NC score	0.548156 (rank : 27)	θ value	4.00176e-32 (rank : 8)
Query Neighborhood Hits	289	Target Neighborhood Hits	1088	Shared Neighborhood Hits	183
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GRIP1_HUMAN
NC score	0.546633 (rank : 28)	θ value	7.59969e-07 (rank : 34)
Query Neighborhood Hits	289	Target Neighborhood Hits	231	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP2_HUMAN
NC score	0.546087 (rank : 29)	θ value	0.000158464 (rank : 66)
Query Neighborhood Hits	289	Target Neighborhood Hits	256	Shared Neighborhood Hits	169
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

PDZD7_HUMAN
NC score	0.544512 (rank : 30)	θ value	0.00102713 (rank : 81)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	152
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

GRIP1_MOUSE
NC score	0.542414 (rank : 31)	θ value	4.92598e-06 (rank : 42)
Query Neighborhood Hits	289	Target Neighborhood Hits	241	Shared Neighborhood Hits	171
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PDZD2_HUMAN
NC score	0.539887 (rank : 32)	θ value	8.40245e-06 (rank : 48)
Query Neighborhood Hits	289	Target Neighborhood Hits	772	Shared Neighborhood Hits	191
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LIN7C_HUMAN
NC score	0.530741 (rank : 33)	θ value	0.00665767 (rank : 94)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.530741 (rank : 34)	θ value	0.00665767 (rank : 95)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	164
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

GOPC_MOUSE
NC score	0.530392 (rank : 35)	θ value	1.17247e-07 (rank : 26)
Query Neighborhood Hits	289	Target Neighborhood Hits	323	Shared Neighborhood Hits	151
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LIN7B_HUMAN
NC score	0.530110 (rank : 36)	θ value	0.0252991 (rank : 109)
Query Neighborhood Hits	289	Target Neighborhood Hits	200	Shared Neighborhood Hits	166
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

TX1B3_HUMAN
NC score	0.527393 (rank : 37)	θ value	0.0563607 (rank : 124)
Query Neighborhood Hits	289	Target Neighborhood Hits	161	Shared Neighborhood Hits	142
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

LIN7B_MOUSE
NC score	0.527319 (rank : 38)	θ value	0.0330416 (rank : 112)
Query Neighborhood Hits	289	Target Neighborhood Hits	200	Shared Neighborhood Hits	166
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LNX2_MOUSE
NC score	0.526358 (rank : 39)	θ value	6.43352e-06 (rank : 44)
Query Neighborhood Hits	289	Target Neighborhood Hits	407	Shared Neighborhood Hits	160
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TX1B3_MOUSE
NC score	0.524406 (rank : 40)	θ value	0.0563607 (rank : 125)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	139
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

GOPC_HUMAN
NC score	0.520241 (rank : 41)	θ value	9.92553e-07 (rank : 36)
Query Neighborhood Hits	289	Target Neighborhood Hits	377	Shared Neighborhood Hits	152
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

LNX1_MOUSE
NC score	0.520212 (rank : 42)	θ value	4.1701e-05 (rank : 54)
Query Neighborhood Hits	289	Target Neighborhood Hits	377	Shared Neighborhood Hits	160
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LIN7A_HUMAN
NC score	0.518623 (rank : 43)	θ value	0.163984 (rank : 142)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.518510 (rank : 44)	θ value	0.163984 (rank : 143)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

PAR3L_HUMAN
NC score	0.515651 (rank : 45)	θ value	0.00175202 (rank : 82)
Query Neighborhood Hits	289	Target Neighborhood Hits	297	Shared Neighborhood Hits	148
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

LNX1_HUMAN
NC score	0.514930 (rank : 46)	θ value	0.000270298 (rank : 71)
Query Neighborhood Hits	289	Target Neighborhood Hits	379	Shared Neighborhood Hits	150
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PARD3_HUMAN
NC score	0.509586 (rank : 47)	θ value	9.29e-05 (rank : 63)
Query Neighborhood Hits	289	Target Neighborhood Hits	312	Shared Neighborhood Hits	158
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LNX2_HUMAN
NC score	0.508858 (rank : 48)	θ value	7.1131e-05 (rank : 59)
Query Neighborhood Hits	289	Target Neighborhood Hits	389	Shared Neighborhood Hits	160
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

USH1C_MOUSE
NC score	0.506963 (rank : 49)	θ value	0.00869519 (rank : 99)
Query Neighborhood Hits	289	Target Neighborhood Hits	557	Shared Neighborhood Hits	178
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

SNTB2_MOUSE
NC score	0.504888 (rank : 50)	θ value	9.92553e-07 (rank : 38)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	143
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

MAGI1_HUMAN
NC score	0.504668 (rank : 51)	θ value	0.00020696 (rank : 69)
Query Neighborhood Hits	289	Target Neighborhood Hits	388	Shared Neighborhood Hits	187
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

SNTB2_HUMAN
NC score	0.504408 (rank : 52)	θ value	9.92553e-07 (rank : 37)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	143
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_HUMAN
NC score	0.503702 (rank : 53)	θ value	0.00020696 (rank : 70)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PARD3_MOUSE
NC score	0.502893 (rank : 54)	θ value	0.000461057 (rank : 75)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	155
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

MAGI1_MOUSE
NC score	0.497712 (rank : 55)	θ value	0.00102713 (rank : 80)
Query Neighborhood Hits	289	Target Neighborhood Hits	403	Shared Neighborhood Hits	191
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

IL16_HUMAN
NC score	0.496745 (rank : 56)	θ value	0.0961366 (rank : 133)
Query Neighborhood Hits	289	Target Neighborhood Hits	207	Shared Neighborhood Hits	138
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZD1_MOUSE
NC score	0.494292 (rank : 57)	θ value	5.44631e-05 (rank : 58)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	144
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTA1_HUMAN
NC score	0.492539 (rank : 58)	θ value	1.29631e-06 (rank : 41)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	148
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
NC score	0.489670 (rank : 59)	θ value	3.41135e-07 (rank : 29)
Query Neighborhood Hits	289	Target Neighborhood Hits	170	Shared Neighborhood Hits	141
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

MAGI2_MOUSE
NC score	0.488538 (rank : 60)	θ value	9.29e-05 (rank : 62)
Query Neighborhood Hits	289	Target Neighborhood Hits	370	Shared Neighborhood Hits	180
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PDZD1_HUMAN
NC score	0.486438 (rank : 61)	θ value	0.000158464 (rank : 67)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	139
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

MAGI2_HUMAN
NC score	0.483154 (rank : 62)	θ value	9.29e-05 (rank : 61)
Query Neighborhood Hits	289	Target Neighborhood Hits	373	Shared Neighborhood Hits	183
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SNTB1_HUMAN
NC score	0.480000 (rank : 63)	θ value	8.40245e-06 (rank : 49)
Query Neighborhood Hits	289	Target Neighborhood Hits	157	Shared Neighborhood Hits	133
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.479209 (rank : 64)	θ value	8.40245e-06 (rank : 50)
Query Neighborhood Hits	289	Target Neighborhood Hits	160	Shared Neighborhood Hits	131
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTG2_MOUSE
NC score	0.475993 (rank : 65)	θ value	0.00390308 (rank : 90)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

IL16_MOUSE
NC score	0.475301 (rank : 66)	θ value	0.279714 (rank : 154)
Query Neighborhood Hits	289	Target Neighborhood Hits	189	Shared Neighborhood Hits	138
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MPP3_HUMAN
NC score	0.469287 (rank : 67)	θ value	0.00298849 (rank : 86)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
NC score	0.464933 (rank : 68)	θ value	0.000270298 (rank : 72)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

EM55_MOUSE
NC score	0.463602 (rank : 69)	θ value	1.09739e-05 (rank : 51)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	115
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

MPP2_MOUSE
NC score	0.457851 (rank : 70)	θ value	1.99992e-07 (rank : 28)
Query Neighborhood Hits	289	Target Neighborhood Hits	189	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

SNTG1_HUMAN
NC score	0.455640 (rank : 71)	θ value	0.00390308 (rank : 89)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_MOUSE
NC score	0.455314 (rank : 72)	θ value	0.00298849 (rank : 87)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

MPP2_HUMAN
NC score	0.454341 (rank : 73)	θ value	4.45536e-07 (rank : 30)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	88
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

EM55_HUMAN
NC score	0.453962 (rank : 74)	θ value	0.000786445 (rank : 79)
Query Neighborhood Hits	289	Target Neighborhood Hits	228	Shared Neighborhood Hits	116
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

PZRN4_HUMAN
NC score	0.453724 (rank : 75)	θ value	0.000270298 (rank : 73)
Query Neighborhood Hits	289	Target Neighborhood Hits	438	Shared Neighborhood Hits	144
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_HUMAN
NC score	0.453599 (rank : 76)	θ value	0.000602161 (rank : 76)
Query Neighborhood Hits	289	Target Neighborhood Hits	461	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
NC score	0.451656 (rank : 77)	θ value	0.000602161 (rank : 77)
Query Neighborhood Hits	289	Target Neighborhood Hits	447	Shared Neighborhood Hits	146
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

MPP6_HUMAN
NC score	0.443551 (rank : 78)	θ value	6.43352e-06 (rank : 47)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

PDZD3_HUMAN
NC score	0.443040 (rank : 79)	θ value	0.00665767 (rank : 96)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	143
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

MPP6_MOUSE
NC score	0.437248 (rank : 80)	θ value	0.000121331 (rank : 65)
Query Neighborhood Hits	289	Target Neighborhood Hits	187	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NHERF_MOUSE
NC score	0.435881 (rank : 81)	θ value	0.279714 (rank : 157)
Query Neighborhood Hits	289	Target Neighborhood Hits	195	Shared Neighborhood Hits	142
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

MPP4_HUMAN
NC score	0.427273 (rank : 82)	θ value	0.813845 (rank : 178)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	127
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NHRF2_HUMAN
NC score	0.419434 (rank : 83)	θ value	0.163984 (rank : 145)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	151
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHERF_HUMAN
NC score	0.418158 (rank : 84)	θ value	0.279714 (rank : 156)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	141
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
NC score	0.406708 (rank : 85)	θ value	0.125558 (rank : 141)
Query Neighborhood Hits	289	Target Neighborhood Hits	194	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

LAP4_HUMAN
NC score	0.402593 (rank : 86)	θ value	1.38499e-08 (rank : 21)
Query Neighborhood Hits	289	Target Neighborhood Hits	608	Shared Neighborhood Hits	178
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MPP4_MOUSE
NC score	0.400691 (rank : 87)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

LAP4_MOUSE
NC score	0.399876 (rank : 88)	θ value	2.36244e-08 (rank : 24)
Query Neighborhood Hits	289	Target Neighborhood Hits	590	Shared Neighborhood Hits	182
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PDZD3_MOUSE
NC score	0.397148 (rank : 89)	θ value	0.0252991 (rank : 111)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	140
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

K1849_HUMAN
NC score	0.382060 (rank : 90)	θ value	0.00509761 (rank : 91)
Query Neighborhood Hits	289	Target Neighborhood Hits	220	Shared Neighborhood Hits	132
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
NC score	0.380101 (rank : 91)	θ value	0.00390308 (rank : 88)
Query Neighborhood Hits	289	Target Neighborhood Hits	335	Shared Neighborhood Hits	140
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PTN13_HUMAN
NC score	0.363964 (rank : 92)	θ value	1.86753e-13 (rank : 16)
Query Neighborhood Hits	289	Target Neighborhood Hits	471	Shared Neighborhood Hits	173
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
NC score	0.358024 (rank : 93)	θ value	1.80886e-08 (rank : 23)
Query Neighborhood Hits	289	Target Neighborhood Hits	426	Shared Neighborhood Hits	179
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PDZK4_HUMAN
NC score	0.354721 (rank : 94)	θ value	0.0563607 (rank : 120)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

DVL3_MOUSE
NC score	0.352913 (rank : 95)	θ value	0.0252991 (rank : 108)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PDZK4_MOUSE
NC score	0.352655 (rank : 96)	θ value	0.0431538 (rank : 116)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SDCB1_MOUSE
NC score	0.352619 (rank : 97)	θ value	0.0563607 (rank : 122)
Query Neighborhood Hits	289	Target Neighborhood Hits	144	Shared Neighborhood Hits	124
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

DVL3_HUMAN
NC score	0.351952 (rank : 98)	θ value	0.0252991 (rank : 107)
Query Neighborhood Hits	289	Target Neighborhood Hits	194	Shared Neighborhood Hits	109
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SDCB1_HUMAN
NC score	0.350743 (rank : 99)	θ value	0.0563607 (rank : 121)
Query Neighborhood Hits	289	Target Neighborhood Hits	150	Shared Neighborhood Hits	126
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

NEB1_HUMAN
NC score	0.348904 (rank : 100)	θ value	4.1701e-05 (rank : 55)
Query Neighborhood Hits	289	Target Neighborhood Hits	829	Shared Neighborhood Hits	145
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DVL1_HUMAN
NC score	0.348186 (rank : 101)	θ value	0.0563607 (rank : 118)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	110
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

AFAD_HUMAN
NC score	0.347022 (rank : 102)	θ value	0.0252991 (rank : 104)
Query Neighborhood Hits	289	Target Neighborhood Hits	689	Shared Neighborhood Hits	145
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DVL1_MOUSE
NC score	0.343842 (rank : 103)	θ value	0.0563607 (rank : 119)
Query Neighborhood Hits	289	Target Neighborhood Hits	146	Shared Neighborhood Hits	108
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1L_HUMAN
NC score	0.337208 (rank : 104)	θ value	0.0736092 (rank : 127)
Query Neighborhood Hits	289	Target Neighborhood Hits	146	Shared Neighborhood Hits	107
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

NEB2_HUMAN
NC score	0.336878 (rank : 105)	θ value	2.44474e-05 (rank : 52)
Query Neighborhood Hits	289	Target Neighborhood Hits	883	Shared Neighborhood Hits	131
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

KGUA_MOUSE
NC score	0.336822 (rank : 106)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	289	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

DVL2_HUMAN
NC score	0.336579 (rank : 107)	θ value	0.0252991 (rank : 105)
Query Neighborhood Hits	289	Target Neighborhood Hits	223	Shared Neighborhood Hits	110
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.335824 (rank : 108)	θ value	0.0252991 (rank : 106)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	112
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

NEB2_MOUSE
NC score	0.333531 (rank : 109)	θ value	2.44474e-05 (rank : 53)
Query Neighborhood Hits	289	Target Neighborhood Hits	889	Shared Neighborhood Hits	131
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

KGUA_HUMAN
NC score	0.330589 (rank : 110)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	289	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

RPGF6_HUMAN
NC score	0.330562 (rank : 111)	θ value	0.000602161 (rank : 78)
Query Neighborhood Hits	289	Target Neighborhood Hits	266	Shared Neighborhood Hits	146
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

APBA1_HUMAN
NC score	0.305333 (rank : 112)	θ value	0.0961366 (rank : 131)
Query Neighborhood Hits	289	Target Neighborhood Hits	325	Shared Neighborhood Hits	142
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PDLI2_HUMAN
NC score	0.300173 (rank : 113)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

APBA3_MOUSE
NC score	0.290823 (rank : 114)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	121
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SDCB2_MOUSE
NC score	0.287055 (rank : 115)	θ value	1.06291 (rank : 188)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	102
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RPGF2_HUMAN
NC score	0.286362 (rank : 116)	θ value	0.00228821 (rank : 84)
Query Neighborhood Hits	289	Target Neighborhood Hits	242	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

CAR14_HUMAN
NC score	0.282142 (rank : 117)	θ value	7.09661e-13 (rank : 17)
Query Neighborhood Hits	289	Target Neighborhood Hits	449	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

SDCB2_HUMAN
NC score	0.277110 (rank : 118)	θ value	0.813845 (rank : 179)
Query Neighborhood Hits	289	Target Neighborhood Hits	121	Shared Neighborhood Hits	109
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

PDLI2_MOUSE
NC score	0.275782 (rank : 119)	θ value	0.0148317 (rank : 102)
Query Neighborhood Hits	289	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

STXB4_HUMAN
NC score	0.274560 (rank : 120)	θ value	1.38821 (rank : 197)
Query Neighborhood Hits	289	Target Neighborhood Hits	616	Shared Neighborhood Hits	106
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBA2_HUMAN
NC score	0.271301 (rank : 121)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	289	Target Neighborhood Hits	220	Shared Neighborhood Hits	136
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
NC score	0.271269 (rank : 122)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	289	Target Neighborhood Hits	219	Shared Neighborhood Hits	136
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

RHPN1_MOUSE
NC score	0.268867 (rank : 123)	θ value	0.00509761 (rank : 92)
Query Neighborhood Hits	289	Target Neighborhood Hits	154	Shared Neighborhood Hits	116
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PICK1_MOUSE
NC score	0.267964 (rank : 124)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	289	Target Neighborhood Hits	131	Shared Neighborhood Hits	112
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

ARHGB_HUMAN
NC score	0.266801 (rank : 125)	θ value	0.000121331 (rank : 64)
Query Neighborhood Hits	289	Target Neighborhood Hits	375	Shared Neighborhood Hits	146
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PICK1_HUMAN
NC score	0.265942 (rank : 126)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	289	Target Neighborhood Hits	132	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APBA3_HUMAN
NC score	0.265692 (rank : 127)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	289	Target Neighborhood Hits	201	Shared Neighborhood Hits	129
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6B_MOUSE
NC score	0.264114 (rank : 128)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	289	Target Neighborhood Hits	128	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_HUMAN
NC score	0.262162 (rank : 129)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	289	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

STXB4_MOUSE
NC score	0.261169 (rank : 130)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	289	Target Neighborhood Hits	629	Shared Neighborhood Hits	105
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PAR6G_HUMAN
NC score	0.255495 (rank : 131)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	289	Target Neighborhood Hits	159	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
NC score	0.253884 (rank : 132)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	289	Target Neighborhood Hits	121	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

SYP2L_HUMAN
NC score	0.250305 (rank : 133)	θ value	1.06291 (rank : 190)
Query Neighborhood Hits	289	Target Neighborhood Hits	400	Shared Neighborhood Hits	125
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ARHGC_HUMAN
NC score	0.249513 (rank : 134)	θ value	0.0148317 (rank : 101)
Query Neighborhood Hits	289	Target Neighborhood Hits	351	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LRRC7_HUMAN
NC score	0.249150 (rank : 135)	θ value	6.43352e-06 (rank : 45)
Query Neighborhood Hits	289	Target Neighborhood Hits	423	Shared Neighborhood Hits	117
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

CAR11_HUMAN
NC score	0.248784 (rank : 136)	θ value	1.80886e-08 (rank : 22)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

LRRC7_MOUSE
NC score	0.247698 (rank : 137)	θ value	6.43352e-06 (rank : 46)
Query Neighborhood Hits	289	Target Neighborhood Hits	416	Shared Neighborhood Hits	113
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

RHPN1_HUMAN
NC score	0.245580 (rank : 138)	θ value	0.0961366 (rank : 136)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	111
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

ARHGC_MOUSE
NC score	0.245510 (rank : 139)	θ value	0.00665767 (rank : 93)
Query Neighborhood Hits	289	Target Neighborhood Hits	344	Shared Neighborhood Hits	139
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CAR14_MOUSE
NC score	0.244100 (rank : 140)	θ value	1.99992e-07 (rank : 27)
Query Neighborhood Hits	289	Target Neighborhood Hits	526	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

LAP2_HUMAN
NC score	0.242669 (rank : 141)	θ value	5.81887e-07 (rank : 31)
Query Neighborhood Hits	289	Target Neighborhood Hits	499	Shared Neighborhood Hits	116
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PAR6A_MOUSE
NC score	0.241185 (rank : 142)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	289	Target Neighborhood Hits	115	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6A_HUMAN
NC score	0.241090 (rank : 143)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

NOS1_HUMAN
NC score	0.235206 (rank : 144)	θ value	0.00869519 (rank : 97)
Query Neighborhood Hits	289	Target Neighborhood Hits	218	Shared Neighborhood Hits	134
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LAP2_MOUSE
NC score	0.234550 (rank : 145)	θ value	7.59969e-07 (rank : 35)
Query Neighborhood Hits	289	Target Neighborhood Hits	482	Shared Neighborhood Hits	109
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GRASP_HUMAN
NC score	0.226363 (rank : 146)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	289	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

CAR10_MOUSE
NC score	0.222871 (rank : 147)	θ value	0.00020696 (rank : 68)
Query Neighborhood Hits	289	Target Neighborhood Hits	407	Shared Neighborhood Hits	27
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

GRASP_MOUSE
NC score	0.222588 (rank : 148)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	289	Target Neighborhood Hits	131	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

RGS12_HUMAN
NC score	0.205722 (rank : 149)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	128
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SYNP2_MOUSE
NC score	0.205643 (rank : 150)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	289	Target Neighborhood Hits	252	Shared Neighborhood Hits	120
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

PSCBP_MOUSE
NC score	0.201265 (rank : 151)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	99
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PSCBP_HUMAN
NC score	0.192570 (rank : 152)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	289	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

SHAN2_HUMAN
NC score	0.190827 (rank : 153)	θ value	0.813845 (rank : 181)
Query Neighborhood Hits	289	Target Neighborhood Hits	346	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PDLI4_MOUSE
NC score	0.186772 (rank : 154)	θ value	0.47712 (rank : 165)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RIMS1_HUMAN
NC score	0.186191 (rank : 155)	θ value	0.365318 (rank : 162)
Query Neighborhood Hits	289	Target Neighborhood Hits	437	Shared Neighborhood Hits	134
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

NOS1_MOUSE
NC score	0.183933 (rank : 156)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	289	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

CAR10_HUMAN
NC score	0.183526 (rank : 157)	θ value	0.00035302 (rank : 74)
Query Neighborhood Hits	289	Target Neighborhood Hits	569	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

PDLI3_HUMAN
NC score	0.183067 (rank : 158)	θ value	3.0926 (rank : 223)
Query Neighborhood Hits	289	Target Neighborhood Hits	199	Shared Neighborhood Hits	96
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SYP2L_MOUSE
NC score	0.171986 (rank : 159)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

APXL_HUMAN
NC score	0.168951 (rank : 160)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	289	Target Neighborhood Hits	553	Shared Neighborhood Hits	105
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PRAX_MOUSE
NC score	0.168341 (rank : 161)	θ value	0.365318 (rank : 161)
Query Neighborhood Hits	289	Target Neighborhood Hits	199	Shared Neighborhood Hits	49
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PDLI3_MOUSE
NC score	0.168096 (rank : 162)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

RIMS2_MOUSE
NC score	0.167641 (rank : 163)	θ value	0.163984 (rank : 146)
Query Neighborhood Hits	289	Target Neighborhood Hits	376	Shared Neighborhood Hits	108
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS2_HUMAN
NC score	0.166621 (rank : 164)	θ value	1.38821 (rank : 194)
Query Neighborhood Hits	289	Target Neighborhood Hits	342	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SHAN2_MOUSE
NC score	0.165666 (rank : 165)	θ value	1.38821 (rank : 196)
Query Neighborhood Hits	289	Target Neighborhood Hits	446	Shared Neighborhood Hits	118
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SYNP2_HUMAN
NC score	0.165536 (rank : 166)	θ value	0.0563607 (rank : 123)
Query Neighborhood Hits	289	Target Neighborhood Hits	323	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PCLO_MOUSE
NC score	0.164582 (rank : 167)	θ value	0.0330416 (rank : 113)
Query Neighborhood Hits	289	Target Neighborhood Hits	2275	Shared Neighborhood Hits	180
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GIPC1_MOUSE
NC score	0.162725 (rank : 168)	θ value	0.813845 (rank : 175)
Query Neighborhood Hits	289	Target Neighborhood Hits	92	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

PDLI4_HUMAN
NC score	0.158174 (rank : 169)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	97
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

GIPC1_HUMAN
NC score	0.158075 (rank : 170)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	81
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

CSKP_HUMAN
NC score	0.155661 (rank : 171)	θ value	5.44631e-05 (rank : 56)
Query Neighborhood Hits	289	Target Neighborhood Hits	1022	Shared Neighborhood Hits	110
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

PDLI1_HUMAN
NC score	0.147099 (rank : 172)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	289	Target Neighborhood Hits	242	Shared Neighborhood Hits	90
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PRAX_HUMAN
NC score	0.146523 (rank : 173)	θ value	0.21417 (rank : 149)
Query Neighborhood Hits	289	Target Neighborhood Hits	215	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PDLI1_MOUSE
NC score	0.146462 (rank : 174)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	289	Target Neighborhood Hits	213	Shared Neighborhood Hits	93
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

CSKP_MOUSE
NC score	0.144203 (rank : 175)	θ value	0.00298849 (rank : 85)
Query Neighborhood Hits	289	Target Neighborhood Hits	1027	Shared Neighborhood Hits	111
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PTN4_HUMAN
NC score	0.138427 (rank : 176)	θ value	0.00869519 (rank : 98)
Query Neighborhood Hits	289	Target Neighborhood Hits	303	Shared Neighborhood Hits	110
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PDLI5_HUMAN
NC score	0.135637 (rank : 177)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	289	Target Neighborhood Hits	322	Shared Neighborhood Hits	109
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LDB3_MOUSE
NC score	0.133087 (rank : 178)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	289	Target Neighborhood Hits	510	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LDB3_HUMAN
NC score	0.132291 (rank : 179)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	289	Target Neighborhood Hits	497	Shared Neighborhood Hits	107
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LMO7_HUMAN
NC score	0.127160 (rank : 180)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	289	Target Neighborhood Hits	507	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PDLI5_MOUSE
NC score	0.126374 (rank : 181)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_HUMAN
NC score	0.124513 (rank : 182)	θ value	0.62314 (rank : 174)
Query Neighborhood Hits	289	Target Neighborhood Hits	547	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PTN3_HUMAN
NC score	0.121942 (rank : 183)	θ value	0.0431538 (rank : 117)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	105
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

GIPC2_HUMAN
NC score	0.121319 (rank : 184)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

SHAN1_HUMAN
NC score	0.118054 (rank : 185)	θ value	0.813845 (rank : 180)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PDZD8_HUMAN
NC score	0.115446 (rank : 186)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PDZD6_HUMAN
NC score	0.111002 (rank : 187)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	289	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PDLI7_MOUSE
NC score	0.102074 (rank : 188)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	289	Target Neighborhood Hits	279	Shared Neighborhood Hits	94
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

HTRA3_MOUSE
NC score	0.099310 (rank : 189)	θ value	0.279714 (rank : 153)
Query Neighborhood Hits	289	Target Neighborhood Hits	156	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA3_HUMAN
NC score	0.086482 (rank : 190)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

CACB1_MOUSE
NC score	0.079106 (rank : 191)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	289	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CNKR2_MOUSE
NC score	0.077157 (rank : 192)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.077078 (rank : 193)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

GIPC2_MOUSE
NC score	0.076190 (rank : 194)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

CACB1_HUMAN
NC score	0.075518 (rank : 195)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	289	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

GIPC3_MOUSE
NC score	0.074859 (rank : 196)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	289	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

CACB4_HUMAN
NC score	0.073499 (rank : 197)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	289	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

GIPC3_HUMAN
NC score	0.072480 (rank : 198)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	289	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

CRK_HUMAN
NC score	0.072242 (rank : 199)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	289	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CACB3_HUMAN
NC score	0.071980 (rank : 200)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	289	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
NC score	0.071475 (rank : 201)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	289	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CRK_MOUSE
NC score	0.071470 (rank : 202)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	289	Target Neighborhood Hits	314	Shared Neighborhood Hits	29
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CACB4_MOUSE
NC score	0.071353 (rank : 203)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	289	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

TIAM1_HUMAN
NC score	0.070882 (rank : 204)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	289	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SRRM1_HUMAN
NC score	0.070238 (rank : 205)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TXND2_HUMAN
NC score	0.065989 (rank : 206)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	289	Target Neighborhood Hits	793	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

GRB2_MOUSE
NC score	0.065766 (rank : 207)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	289	Target Neighborhood Hits	312	Shared Neighborhood Hits	30
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRB2_HUMAN
NC score	0.065050 (rank : 208)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	289	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

CARD9_HUMAN
NC score	0.064440 (rank : 209)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	289	Target Neighborhood Hits	602	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

STAM1_MOUSE
NC score	0.064038 (rank : 210)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	289	Target Neighborhood Hits	273	Shared Neighborhood Hits	30
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SRRM1_MOUSE
NC score	0.060489 (rank : 211)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	289	Target Neighborhood Hits	966	Shared Neighborhood Hits	84
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NBN_MOUSE
NC score	0.058645 (rank : 212)	θ value	0.0113563 (rank : 100)
Query Neighborhood Hits	289	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

CACB2_HUMAN
NC score	0.057142 (rank : 213)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	289	Target Neighborhood Hits	99	Shared Neighborhood Hits	26
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

SRRM2_HUMAN
NC score	0.057117 (rank : 214)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	289	Target Neighborhood Hits	1296	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STAM2_MOUSE
NC score	0.056543 (rank : 215)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	289	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

LRRC1_MOUSE
NC score	0.056501 (rank : 216)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	289	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

LRRC1_HUMAN
NC score	0.056040 (rank : 217)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	289	Target Neighborhood Hits	282	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

STAM1_HUMAN
NC score	0.055661 (rank : 218)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	289	Target Neighborhood Hits	271	Shared Neighborhood Hits	29
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

MUC7_HUMAN
NC score	0.055484 (rank : 219)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	289	Target Neighborhood Hits	538	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SRRM2_MOUSE
NC score	0.055325 (rank : 220)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	289	Target Neighborhood Hits	1470	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TGON2_HUMAN
NC score	0.054691 (rank : 221)	θ value	0.0330416 (rank : 114)
Query Neighborhood Hits	289	Target Neighborhood Hits	1037	Shared Neighborhood Hits	67
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIAM1_MOUSE
NC score	0.054462 (rank : 222)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	51
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

RGS3_MOUSE
NC score	0.054053 (rank : 223)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	289	Target Neighborhood Hits	1621	Shared Neighborhood Hits	128
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

IWS1_HUMAN
NC score	0.053643 (rank : 224)	θ value	1.06291 (rank : 186)
Query Neighborhood Hits	289	Target Neighborhood Hits	1241	Shared Neighborhood Hits	78
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NPHP1_MOUSE
NC score	0.052389 (rank : 225)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	289	Target Neighborhood Hits	267	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

IWS1_MOUSE
NC score	0.051845 (rank : 226)	θ value	0.62314 (rank : 172)
Query Neighborhood Hits	289	Target Neighborhood Hits	1258	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

HTRA1_HUMAN
NC score	0.051273 (rank : 227)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	289	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

RHPN2_MOUSE
NC score	0.051259 (rank : 228)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

CACB2_MOUSE
NC score	0.050913 (rank : 229)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	289	Target Neighborhood Hits	94	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

MAST4_HUMAN
NC score	0.050218 (rank : 230)	θ value	0.47712 (rank : 164)
Query Neighborhood Hits	289	Target Neighborhood Hits	1804	Shared Neighborhood Hits	155
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MY18A_MOUSE
NC score	0.050125 (rank : 231)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	289	Target Neighborhood Hits	1989	Shared Neighborhood Hits	169
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

K1543_MOUSE
NC score	0.049300 (rank : 232)	θ value	0.125558 (rank : 138)
Query Neighborhood Hits	289	Target Neighborhood Hits	497	Shared Neighborhood Hits	49
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NPBL_MOUSE
NC score	0.048895 (rank : 233)	θ value	0.0252991 (rank : 110)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	70
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TARA_HUMAN
NC score	0.046113 (rank : 234)	θ value	0.21417 (rank : 150)
Query Neighborhood Hits	289	Target Neighborhood Hits	1626	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MAST2_HUMAN
NC score	0.045273 (rank : 235)	θ value	0.47712 (rank : 163)
Query Neighborhood Hits	289	Target Neighborhood Hits	1189	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SETX_HUMAN
NC score	0.044895 (rank : 236)	θ value	0.0736092 (rank : 130)
Query Neighborhood Hits	289	Target Neighborhood Hits	368	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

NACAM_MOUSE
NC score	0.044819 (rank : 237)	θ value	0.0736092 (rank : 129)
Query Neighborhood Hits	289	Target Neighborhood Hits	1866	Shared Neighborhood Hits	96
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CASC3_MOUSE
NC score	0.044454 (rank : 238)	θ value	0.0961366 (rank : 132)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

MAST2_MOUSE
NC score	0.043097 (rank : 239)	θ value	1.38821 (rank : 193)
Query Neighborhood Hits	289	Target Neighborhood Hits	1110	Shared Neighborhood Hits	119
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

RBBP6_HUMAN
NC score	0.042066 (rank : 240)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TARA_MOUSE
NC score	0.041156 (rank : 241)	θ value	1.38821 (rank : 198)
Query Neighborhood Hits	289	Target Neighborhood Hits	1133	Shared Neighborhood Hits	69
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NIPBL_HUMAN
NC score	0.041070 (rank : 242)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	289	Target Neighborhood Hits	1311	Shared Neighborhood Hits	82
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MBB1A_HUMAN
NC score	0.041017 (rank : 243)	θ value	0.813845 (rank : 177)
Query Neighborhood Hits	289	Target Neighborhood Hits	665	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MAST3_HUMAN
NC score	0.040759 (rank : 244)	θ value	0.163984 (rank : 144)
Query Neighborhood Hits	289	Target Neighborhood Hits	1128	Shared Neighborhood Hits	121
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

HTRA4_HUMAN
NC score	0.040613 (rank : 245)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	36
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

BAT2_HUMAN
NC score	0.039757 (rank : 246)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	289	Target Neighborhood Hits	931	Shared Neighborhood Hits	67
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ELOA1_MOUSE
NC score	0.039507 (rank : 247)	θ value	0.21417 (rank : 147)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

E41LA_HUMAN
NC score	0.039506 (rank : 248)	θ value	0.62314 (rank : 170)
Query Neighborhood Hits	289	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

MAST1_MOUSE
NC score	0.039164 (rank : 249)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	289	Target Neighborhood Hits	1123	Shared Neighborhood Hits	121
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_HUMAN
NC score	0.038764 (rank : 250)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	289	Target Neighborhood Hits	1146	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SET1A_HUMAN
NC score	0.037994 (rank : 251)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EFS_MOUSE
NC score	0.037831 (rank : 252)	θ value	1.81305 (rank : 203)
Query Neighborhood Hits	289	Target Neighborhood Hits	389	Shared Neighborhood Hits	28
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

BAT2_MOUSE
NC score	0.037413 (rank : 253)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	289	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SF3B1_HUMAN
NC score	0.037326 (rank : 254)	θ value	0.47712 (rank : 167)
Query Neighborhood Hits	289	Target Neighborhood Hits	341	Shared Neighborhood Hits	24
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

C8AP2_MOUSE
NC score	0.037320 (rank : 255)	θ value	0.0431538 (rank : 115)
Query Neighborhood Hits	289	Target Neighborhood Hits	405	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

SF3B1_MOUSE
NC score	0.037229 (rank : 256)	θ value	0.47712 (rank : 168)
Query Neighborhood Hits	289	Target Neighborhood Hits	352	Shared Neighborhood Hits	23
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

LIMK2_MOUSE
NC score	0.035530 (rank : 257)	θ value	0.0961366 (rank : 134)
Query Neighborhood Hits	289	Target Neighborhood Hits	998	Shared Neighborhood Hits	62
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

EFS_HUMAN
NC score	0.035377 (rank : 258)	θ value	1.81305 (rank : 202)
Query Neighborhood Hits	289	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

CCD55_HUMAN
NC score	0.034417 (rank : 259)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	289	Target Neighborhood Hits	513	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NFH_MOUSE
NC score	0.033843 (rank : 260)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	289	Target Neighborhood Hits	2247	Shared Neighborhood Hits	106
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LIMK2_HUMAN
NC score	0.033079 (rank : 261)	θ value	0.125558 (rank : 139)
Query Neighborhood Hits	289	Target Neighborhood Hits	986	Shared Neighborhood Hits	63
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIPB2_HUMAN
NC score	0.032917 (rank : 262)	θ value	0.125558 (rank : 140)
Query Neighborhood Hits	289	Target Neighborhood Hits	599	Shared Neighborhood Hits	28
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

CCD55_MOUSE
NC score	0.032828 (rank : 263)	θ value	1.06291 (rank : 183)
Query Neighborhood Hits	289	Target Neighborhood Hits	519	Shared Neighborhood Hits	38
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ELOA1_HUMAN
NC score	0.032570 (rank : 264)	θ value	1.06291 (rank : 185)
Query Neighborhood Hits	289	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

TXND2_MOUSE
NC score	0.032357 (rank : 265)	θ value	0.21417 (rank : 151)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

E41LB_MOUSE
NC score	0.030874 (rank : 266)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	289	Target Neighborhood Hits	59	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

LIMK1_HUMAN
NC score	0.029459 (rank : 267)	θ value	0.0736092 (rank : 128)
Query Neighborhood Hits	289	Target Neighborhood Hits	1005	Shared Neighborhood Hits	74
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

YLPM1_MOUSE
NC score	0.029295 (rank : 268)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	289	Target Neighborhood Hits	505	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CYLC1_HUMAN
NC score	0.028619 (rank : 269)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

RSF1_HUMAN
NC score	0.028393 (rank : 270)	θ value	1.38821 (rank : 195)
Query Neighborhood Hits	289	Target Neighborhood Hits	539	Shared Neighborhood Hits	31
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

K0562_MOUSE
NC score	0.028152 (rank : 271)	θ value	0.279714 (rank : 155)
Query Neighborhood Hits	289	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

SETD2_HUMAN
NC score	0.028099 (rank : 272)	θ value	1.06291 (rank : 189)
Query Neighborhood Hits	289	Target Neighborhood Hits	412	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CI079_HUMAN
NC score	0.027395 (rank : 273)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	289	Target Neighborhood Hits	288	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

LIMK1_MOUSE
NC score	0.027306 (rank : 274)	θ value	0.21417 (rank : 148)
Query Neighborhood Hits	289	Target Neighborhood Hits	1008	Shared Neighborhood Hits	76
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

BAG3_HUMAN
NC score	0.026934 (rank : 275)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	289	Target Neighborhood Hits	314	Shared Neighborhood Hits	27
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

NELFE_HUMAN
NC score	0.026668 (rank : 276)	θ value	0.62314 (rank : 173)
Query Neighborhood Hits	289	Target Neighborhood Hits	107	Shared Neighborhood Hits	10
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

ADDB_MOUSE
NC score	0.026587 (rank : 277)	θ value	0.125558 (rank : 137)
Query Neighborhood Hits	289	Target Neighborhood Hits	574	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

LYSM2_MOUSE
NC score	0.026343 (rank : 278)	θ value	1.38821 (rank : 192)
Query Neighborhood Hits	289	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7V2, Q80ZR2	Gene names	Lysmd2
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 2.

RECQ5_HUMAN
NC score	0.025589 (rank : 279)	θ value	0.47712 (rank : 166)
Query Neighborhood Hits	289	Target Neighborhood Hits	390	Shared Neighborhood Hits	32
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

CSF1_HUMAN
NC score	0.025288 (rank : 280)	θ value	1.06291 (rank : 184)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

LIPB2_MOUSE
NC score	0.025105 (rank : 281)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	289	Target Neighborhood Hits	570	Shared Neighborhood Hits	28
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

CABIN_HUMAN
NC score	0.024805 (rank : 282)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	289	Target Neighborhood Hits	490	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CD008_HUMAN
NC score	0.024726 (rank : 283)	θ value	1.81305 (rank : 200)
Query Neighborhood Hits	289	Target Neighborhood Hits	330	Shared Neighborhood Hits	18
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

PTN14_HUMAN
NC score	0.024708 (rank : 284)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	289	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

AN32A_HUMAN
NC score	0.024474 (rank : 285)	θ value	1.81305 (rank : 199)
Query Neighborhood Hits	289	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

RGNEF_MOUSE
NC score	0.023933 (rank : 286)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	289	Target Neighborhood Hits	641	Shared Neighborhood Hits	30
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

PCQAP_HUMAN
NC score	0.023817 (rank : 287)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	289	Target Neighborhood Hits	549	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

MLL3_HUMAN
NC score	0.023735 (rank : 288)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	289	Target Neighborhood Hits	1644	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

LIPS_HUMAN
NC score	0.023145 (rank : 289)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	289	Target Neighborhood Hits	314	Shared Neighborhood Hits	33
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

CMTA1_HUMAN
NC score	0.022813 (rank : 290)	θ value	1.38821 (rank : 191)
Query Neighborhood Hits	289	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RUSC1_HUMAN
NC score	0.022403 (rank : 291)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	289	Target Neighborhood Hits	226	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

CBP_HUMAN
NC score	0.022182 (rank : 292)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	289	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

WWP2_HUMAN
NC score	0.022086 (rank : 293)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

SNIP_HUMAN
NC score	0.021642 (rank : 294)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	289	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

GOGB1_HUMAN
NC score	0.020929 (rank : 295)	θ value	1.81305 (rank : 204)
Query Neighborhood Hits	289	Target Neighborhood Hits	2297	Shared Neighborhood Hits	75
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MLF2_MOUSE
NC score	0.020536 (rank : 296)	θ value	1.06291 (rank : 187)
Query Neighborhood Hits	289	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KX1	Gene names	Mlf2
Domain Architecture	No domain graphic available
Description	Myeloid leukemia factor 2 (Myelodysplasia-myeloid leukemia factor 2).

ASPP1_MOUSE
NC score	0.020397 (rank : 297)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	289	Target Neighborhood Hits	1244	Shared Neighborhood Hits	58
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PCQAP_MOUSE
NC score	0.020219 (rank : 298)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	289	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

LIPA1_HUMAN
NC score	0.019085 (rank : 299)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	289	Target Neighborhood Hits	1294	Shared Neighborhood Hits	52
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

SCG3_HUMAN
NC score	0.018974 (rank : 300)	θ value	1.81305 (rank : 207)
Query Neighborhood Hits	289	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXD2, Q96C83, Q96GE8, Q9Y6G7	Gene names	SCG3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

AFF3_HUMAN
NC score	0.018556 (rank : 301)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

CO039_HUMAN
NC score	0.018396 (rank : 302)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	289	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

BOP1_HUMAN
NC score	0.018101 (rank : 303)	θ value	1.06291 (rank : 182)
Query Neighborhood Hits	289	Target Neighborhood Hits	257	Shared Neighborhood Hits	5
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

SNIP_MOUSE
NC score	0.017817 (rank : 304)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	289	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

HCLS1_MOUSE
NC score	0.017381 (rank : 305)	θ value	1.81305 (rank : 205)
Query Neighborhood Hits	289	Target Neighborhood Hits	329	Shared Neighborhood Hits	22
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

MAP9_MOUSE
NC score	0.017367 (rank : 306)	θ value	1.81305 (rank : 206)
Query Neighborhood Hits	289	Target Neighborhood Hits	529	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PHLB1_HUMAN
NC score	0.016845 (rank : 307)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	289	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RBM16_HUMAN
NC score	0.016218 (rank : 308)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	289	Target Neighborhood Hits	300	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

IF3A_HUMAN
NC score	0.016113 (rank : 309)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	289	Target Neighborhood Hits	875	Shared Neighborhood Hits	38
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

SPT5H_MOUSE
NC score	0.015929 (rank : 310)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	289	Target Neighborhood Hits	437	Shared Neighborhood Hits	33
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.015915 (rank : 311)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	289	Target Neighborhood Hits	436	Shared Neighborhood Hits	31
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

CIC_HUMAN
NC score	0.015709 (rank : 312)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	289	Target Neighborhood Hits	992	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RB15B_HUMAN
NC score	0.015501 (rank : 313)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	289	Target Neighborhood Hits	251	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

CCNL1_HUMAN
NC score	0.015352 (rank : 314)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	289	Target Neighborhood Hits	79	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

MYST3_HUMAN
NC score	0.014621 (rank : 315)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	289	Target Neighborhood Hits	772	Shared Neighborhood Hits	43
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ETV6_HUMAN
NC score	0.014013 (rank : 316)	θ value	0.62314 (rank : 171)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

AKAP2_HUMAN
NC score	0.013709 (rank : 317)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	289	Target Neighborhood Hits	507	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AP3B2_HUMAN
NC score	0.013257 (rank : 318)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	289	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

SYTL2_HUMAN
NC score	0.013112 (rank : 319)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	289	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

ATBF1_HUMAN
NC score	0.013066 (rank : 320)	θ value	0.279714 (rank : 152)
Query Neighborhood Hits	289	Target Neighborhood Hits	1547	Shared Neighborhood Hits	47
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

NCOR1_HUMAN
NC score	0.012372 (rank : 321)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	289	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

CNGB1_HUMAN
NC score	0.011344 (rank : 322)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	289	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

FOSL1_HUMAN
NC score	0.010822 (rank : 323)	θ value	3.0926 (rank : 220)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

RBM6_HUMAN
NC score	0.010606 (rank : 324)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	15
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

WDFY3_HUMAN
NC score	0.009344 (rank : 325)	θ value	0.47712 (rank : 169)
Query Neighborhood Hits	289	Target Neighborhood Hits	348	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

MKL1_HUMAN
NC score	0.007933 (rank : 326)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	289	Target Neighborhood Hits	232	Shared Neighborhood Hits	15
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

CAC1A_MOUSE
NC score	0.007776 (rank : 327)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	289	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

M4K4_MOUSE
NC score	0.007704 (rank : 328)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	289	Target Neighborhood Hits	1560	Shared Neighborhood Hits	53
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

DDX10_HUMAN
NC score	0.007486 (rank : 329)	θ value	0.365318 (rank : 158)
Query Neighborhood Hits	289	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DHX37_HUMAN
NC score	0.007463 (rank : 330)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	289	Target Neighborhood Hits	133	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

RHG06_HUMAN
NC score	0.007174 (rank : 331)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

DMD_MOUSE
NC score	0.006820 (rank : 332)	θ value	3.0926 (rank : 219)
Query Neighborhood Hits	289	Target Neighborhood Hits	1111	Shared Neighborhood Hits	36
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ST5_HUMAN
NC score	0.006817 (rank : 333)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	289	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

PEG3_MOUSE
NC score	0.006695 (rank : 334)	θ value	0.0961366 (rank : 135)
Query Neighborhood Hits	289	Target Neighborhood Hits	1101	Shared Neighborhood Hits	31
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RHG06_MOUSE
NC score	0.006529 (rank : 335)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	289	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CAC1A_HUMAN
NC score	0.006474 (rank : 336)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	289	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SYV_HUMAN
NC score	0.006394 (rank : 337)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	289	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

MYO9B_HUMAN
NC score	0.006353 (rank : 338)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	289	Target Neighborhood Hits	641	Shared Neighborhood Hits	46
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

HES1_HUMAN
NC score	0.005351 (rank : 339)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	289	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

CD248_MOUSE
NC score	0.005218 (rank : 340)	θ value	1.81305 (rank : 201)
Query Neighborhood Hits	289	Target Neighborhood Hits	578	Shared Neighborhood Hits	20
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GIT2_HUMAN
NC score	0.004445 (rank : 341)	θ value	3.0926 (rank : 222)
Query Neighborhood Hits	289	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

FOXL1_MOUSE
NC score	0.002059 (rank : 342)	θ value	3.0926 (rank : 221)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

MYLK_MOUSE
NC score	0.001637 (rank : 343)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	289	Target Neighborhood Hits	1489	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

GLI1_HUMAN
NC score	-0.004048 (rank : 344)	θ value	0.813845 (rank : 176)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	14
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).