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Network neighborhood for query Sequence : WHRN_HUMAN

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WHRN_HUMAN
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WHRN_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	325
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	0 (rank : 2)	NC score	0.973602 (rank : 2)
Query Neighborhood Hits	325	Target Neighborhood Hits	412	Shared Neighborhood Hits	247
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD7_HUMAN
θ value	3.61106e-41 (rank : 3)	NC score	0.907071 (rank : 3)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	177
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

USH1C_HUMAN
θ value	4.72714e-33 (rank : 4)	NC score	0.868187 (rank : 4)
Query Neighborhood Hits	325	Target Neighborhood Hits	327	Shared Neighborhood Hits	198
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	4.00176e-32 (rank : 5)	NC score	0.816638 (rank : 5)
Query Neighborhood Hits	325	Target Neighborhood Hits	557	Shared Neighborhood Hits	211
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

DLG4_MOUSE
θ value	2.35696e-16 (rank : 6)	NC score	0.691286 (rank : 28)
Query Neighborhood Hits	325	Target Neighborhood Hits	282	Shared Neighborhood Hits	181
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
θ value	5.25075e-16 (rank : 7)	NC score	0.689806 (rank : 29)
Query Neighborhood Hits	325	Target Neighborhood Hits	286	Shared Neighborhood Hits	179
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG1_HUMAN
θ value	6.85773e-16 (rank : 8)	NC score	0.675176 (rank : 33)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	172
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	6.85773e-16 (rank : 9)	NC score	0.673038 (rank : 34)
Query Neighborhood Hits	325	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

RPGF6_HUMAN
θ value	7.58209e-15 (rank : 10)	NC score	0.509514 (rank : 75)
Query Neighborhood Hits	325	Target Neighborhood Hits	266	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

DLG3_HUMAN
θ value	1.68911e-14 (rank : 11)	NC score	0.677842 (rank : 32)
Query Neighborhood Hits	325	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	1.68911e-14 (rank : 12)	NC score	0.679441 (rank : 31)
Query Neighborhood Hits	325	Target Neighborhood Hits	274	Shared Neighborhood Hits	178
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

LAP4_MOUSE
θ value	1.68911e-14 (rank : 13)	NC score	0.495438 (rank : 77)
Query Neighborhood Hits	325	Target Neighborhood Hits	590	Shared Neighborhood Hits	205
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

DLG2_HUMAN
θ value	6.41864e-14 (rank : 14)	NC score	0.666189 (rank : 36)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	176
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	8.38298e-14 (rank : 15)	NC score	0.665778 (rank : 37)
Query Neighborhood Hits	325	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LAP4_HUMAN
θ value	1.42992e-13 (rank : 16)	NC score	0.501145 (rank : 76)
Query Neighborhood Hits	325	Target Neighborhood Hits	608	Shared Neighborhood Hits	206
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PZRN3_MOUSE
θ value	1.2105e-12 (rank : 17)	NC score	0.589921 (rank : 68)
Query Neighborhood Hits	325	Target Neighborhood Hits	447	Shared Neighborhood Hits	162
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

NHERF_HUMAN
θ value	1.58096e-12 (rank : 18)	NC score	0.710802 (rank : 21)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	168
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PZRN3_HUMAN
θ value	1.58096e-12 (rank : 19)	NC score	0.584973 (rank : 69)
Query Neighborhood Hits	325	Target Neighborhood Hits	461	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

MPDZ_MOUSE
θ value	3.52202e-12 (rank : 20)	NC score	0.729943 (rank : 16)
Query Neighborhood Hits	325	Target Neighborhood Hits	298	Shared Neighborhood Hits	196
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NHRF2_MOUSE
θ value	6.00763e-12 (rank : 21)	NC score	0.704323 (rank : 23)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	182
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

RPGF2_HUMAN
θ value	7.84624e-12 (rank : 22)	NC score	0.453204 (rank : 81)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

NHERF_MOUSE
θ value	1.33837e-11 (rank : 23)	NC score	0.717456 (rank : 19)
Query Neighborhood Hits	325	Target Neighborhood Hits	195	Shared Neighborhood Hits	170
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

MAGI1_MOUSE
θ value	1.74796e-11 (rank : 24)	NC score	0.660291 (rank : 41)
Query Neighborhood Hits	325	Target Neighborhood Hits	403	Shared Neighborhood Hits	203
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MPDZ_HUMAN
θ value	1.74796e-11 (rank : 25)	NC score	0.726481 (rank : 17)
Query Neighborhood Hits	325	Target Neighborhood Hits	261	Shared Neighborhood Hits	197
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NHRF2_HUMAN
θ value	1.74796e-11 (rank : 26)	NC score	0.709253 (rank : 22)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

INADL_MOUSE
θ value	3.89403e-11 (rank : 27)	NC score	0.733128 (rank : 15)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	199
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INADL_HUMAN
θ value	1.47974e-10 (rank : 28)	NC score	0.726439 (rank : 18)
Query Neighborhood Hits	325	Target Neighborhood Hits	260	Shared Neighborhood Hits	186
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LNX1_MOUSE
θ value	1.9326e-10 (rank : 29)	NC score	0.645794 (rank : 51)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	177
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDZD1_MOUSE
θ value	1.9326e-10 (rank : 30)	NC score	0.713834 (rank : 20)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	168
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

GOPC_HUMAN
θ value	2.52405e-10 (rank : 31)	NC score	0.682170 (rank : 30)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	2.52405e-10 (rank : 32)	NC score	0.692194 (rank : 27)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

MAGI1_HUMAN
θ value	3.29651e-10 (rank : 33)	NC score	0.660517 (rank : 40)
Query Neighborhood Hits	325	Target Neighborhood Hits	388	Shared Neighborhood Hits	198
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PDZ11_HUMAN
θ value	5.62301e-10 (rank : 34)	NC score	0.775959 (rank : 6)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	155
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	5.62301e-10 (rank : 35)	NC score	0.772634 (rank : 7)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LNX1_HUMAN
θ value	9.59137e-10 (rank : 36)	NC score	0.635335 (rank : 55)
Query Neighborhood Hits	325	Target Neighborhood Hits	379	Shared Neighborhood Hits	172
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LIN7B_HUMAN
θ value	1.25267e-09 (rank : 37)	NC score	0.762593 (rank : 8)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	186
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

PTN13_MOUSE
θ value	1.25267e-09 (rank : 38)	NC score	0.414598 (rank : 100)
Query Neighborhood Hits	325	Target Neighborhood Hits	426	Shared Neighborhood Hits	191
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

LIN7A_HUMAN
θ value	1.63604e-09 (rank : 39)	NC score	0.759043 (rank : 11)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	183
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	1.63604e-09 (rank : 40)	NC score	0.759257 (rank : 10)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	183
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_MOUSE
θ value	1.63604e-09 (rank : 41)	NC score	0.760347 (rank : 9)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	186
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

ZO3_MOUSE
θ value	2.79066e-09 (rank : 42)	NC score	0.630840 (rank : 57)
Query Neighborhood Hits	325	Target Neighborhood Hits	224	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LIN7C_HUMAN
θ value	3.64472e-09 (rank : 43)	NC score	0.757795 (rank : 12)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	3.64472e-09 (rank : 44)	NC score	0.757795 (rank : 13)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SNTB2_MOUSE
θ value	4.76016e-09 (rank : 45)	NC score	0.647434 (rank : 49)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	160
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

MAGI2_MOUSE
θ value	8.11959e-09 (rank : 46)	NC score	0.630325 (rank : 58)
Query Neighborhood Hits	325	Target Neighborhood Hits	370	Shared Neighborhood Hits	197
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PTN13_HUMAN
θ value	1.06045e-08 (rank : 47)	NC score	0.420058 (rank : 97)
Query Neighborhood Hits	325	Target Neighborhood Hits	471	Shared Neighborhood Hits	190
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SNTB2_HUMAN
θ value	1.38499e-08 (rank : 48)	NC score	0.646363 (rank : 50)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ZO3_HUMAN
θ value	1.38499e-08 (rank : 49)	NC score	0.612429 (rank : 64)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

MAGI2_HUMAN
θ value	1.80886e-08 (rank : 50)	NC score	0.632943 (rank : 56)
Query Neighborhood Hits	325	Target Neighborhood Hits	373	Shared Neighborhood Hits	193
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PAR3L_HUMAN
θ value	1.80886e-08 (rank : 51)	NC score	0.670370 (rank : 35)
Query Neighborhood Hits	325	Target Neighborhood Hits	297	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD2_HUMAN
θ value	1.80886e-08 (rank : 52)	NC score	0.656325 (rank : 42)
Query Neighborhood Hits	325	Target Neighborhood Hits	772	Shared Neighborhood Hits	218
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SNTA1_HUMAN
θ value	1.80886e-08 (rank : 53)	NC score	0.635390 (rank : 54)
Query Neighborhood Hits	325	Target Neighborhood Hits	186	Shared Neighborhood Hits	167
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	1.80886e-08 (rank : 54)	NC score	0.626802 (rank : 60)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	158
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PDZD3_HUMAN
θ value	2.36244e-08 (rank : 55)	NC score	0.665271 (rank : 38)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	165
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

LNX2_HUMAN
θ value	3.08544e-08 (rank : 56)	NC score	0.640723 (rank : 52)
Query Neighborhood Hits	325	Target Neighborhood Hits	389	Shared Neighborhood Hits	179
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	4.0297e-08 (rank : 57)	NC score	0.650702 (rank : 47)
Query Neighborhood Hits	325	Target Neighborhood Hits	407	Shared Neighborhood Hits	180
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

GRIP2_HUMAN
θ value	3.41135e-07 (rank : 58)	NC score	0.661084 (rank : 39)
Query Neighborhood Hits	325	Target Neighborhood Hits	256	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

PARD3_MOUSE
θ value	4.45536e-07 (rank : 59)	NC score	0.655119 (rank : 44)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	171
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD3_MOUSE
θ value	4.45536e-07 (rank : 60)	NC score	0.638602 (rank : 53)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	163
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZD1_HUMAN
θ value	5.81887e-07 (rank : 61)	NC score	0.695197 (rank : 26)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	169
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTB1_HUMAN
θ value	7.59969e-07 (rank : 62)	NC score	0.605230 (rank : 65)
Query Neighborhood Hits	325	Target Neighborhood Hits	157	Shared Neighborhood Hits	150
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	7.59969e-07 (rank : 63)	NC score	0.603931 (rank : 67)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	147
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

ZO2_HUMAN
θ value	9.92553e-07 (rank : 64)	NC score	0.562561 (rank : 71)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	9.92553e-07 (rank : 65)	NC score	0.561607 (rank : 72)
Query Neighborhood Hits	325	Target Neighborhood Hits	296	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

SNTG2_MOUSE
θ value	1.29631e-06 (rank : 66)	NC score	0.623411 (rank : 61)
Query Neighborhood Hits	325	Target Neighborhood Hits	176	Shared Neighborhood Hits	164
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG2_HUMAN
θ value	1.69304e-06 (rank : 67)	NC score	0.648171 (rank : 48)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	177
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

DLG5_HUMAN
θ value	2.21117e-06 (rank : 68)	NC score	0.433291 (rank : 91)
Query Neighborhood Hits	325	Target Neighborhood Hits	1088	Shared Neighborhood Hits	191
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PZRN4_HUMAN
θ value	2.88788e-06 (rank : 69)	NC score	0.576748 (rank : 70)
Query Neighborhood Hits	325	Target Neighborhood Hits	438	Shared Neighborhood Hits	155
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

GRIP1_HUMAN
θ value	3.77169e-06 (rank : 70)	NC score	0.655109 (rank : 45)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	3.77169e-06 (rank : 71)	NC score	0.655532 (rank : 43)
Query Neighborhood Hits	325	Target Neighborhood Hits	241	Shared Neighborhood Hits	194
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PARD3_HUMAN
θ value	3.77169e-06 (rank : 72)	NC score	0.651042 (rank : 46)
Query Neighborhood Hits	325	Target Neighborhood Hits	312	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

SNTG1_HUMAN
θ value	3.77169e-06 (rank : 73)	NC score	0.615741 (rank : 63)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_MOUSE
θ value	4.92598e-06 (rank : 74)	NC score	0.616603 (rank : 62)
Query Neighborhood Hits	325	Target Neighborhood Hits	179	Shared Neighborhood Hits	168
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SYP2L_HUMAN
θ value	6.43352e-06 (rank : 75)	NC score	0.452550 (rank : 82)
Query Neighborhood Hits	325	Target Neighborhood Hits	400	Shared Neighborhood Hits	141
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ZO1_HUMAN
θ value	6.43352e-06 (rank : 76)	NC score	0.549991 (rank : 74)
Query Neighborhood Hits	325	Target Neighborhood Hits	474	Shared Neighborhood Hits	187
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	6.43352e-06 (rank : 77)	NC score	0.558326 (rank : 73)
Query Neighborhood Hits	325	Target Neighborhood Hits	453	Shared Neighborhood Hits	190
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RHPN1_HUMAN
θ value	1.43324e-05 (rank : 78)	NC score	0.399502 (rank : 105)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

MUC1_HUMAN
θ value	1.87187e-05 (rank : 79)	NC score	0.071114 (rank : 208)
Query Neighborhood Hits	325	Target Neighborhood Hits	975	Shared Neighborhood Hits	90
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ARHGB_HUMAN
θ value	2.44474e-05 (rank : 80)	NC score	0.372791 (rank : 120)
Query Neighborhood Hits	325	Target Neighborhood Hits	375	Shared Neighborhood Hits	175
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

TX1B3_HUMAN
θ value	2.44474e-05 (rank : 81)	NC score	0.700159 (rank : 24)
Query Neighborhood Hits	325	Target Neighborhood Hits	161	Shared Neighborhood Hits	159
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	2.44474e-05 (rank : 82)	NC score	0.697981 (rank : 25)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	156
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PAR6G_HUMAN
θ value	3.19293e-05 (rank : 83)	NC score	0.449989 (rank : 85)
Query Neighborhood Hits	325	Target Neighborhood Hits	159	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

AFAD_HUMAN
θ value	4.1701e-05 (rank : 84)	NC score	0.452318 (rank : 83)
Query Neighborhood Hits	325	Target Neighborhood Hits	689	Shared Neighborhood Hits	155
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

RIMS1_HUMAN
θ value	4.1701e-05 (rank : 85)	NC score	0.270579 (rank : 154)
Query Neighborhood Hits	325	Target Neighborhood Hits	437	Shared Neighborhood Hits	134
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYP2L_MOUSE
θ value	5.44631e-05 (rank : 86)	NC score	0.363207 (rank : 124)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

RGS12_HUMAN
θ value	7.1131e-05 (rank : 87)	NC score	0.331961 (rank : 144)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	147
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

PAR6G_MOUSE
θ value	9.29e-05 (rank : 88)	NC score	0.443994 (rank : 88)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

SHAN1_HUMAN
θ value	9.29e-05 (rank : 89)	NC score	0.234940 (rank : 166)
Query Neighborhood Hits	325	Target Neighborhood Hits	1041	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

LRRC7_HUMAN
θ value	0.000121331 (rank : 90)	NC score	0.264150 (rank : 158)
Query Neighborhood Hits	325	Target Neighborhood Hits	423	Shared Neighborhood Hits	122
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.000121331 (rank : 91)	NC score	0.262645 (rank : 161)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	118
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PAR6B_HUMAN
θ value	0.000121331 (rank : 92)	NC score	0.444092 (rank : 87)
Query Neighborhood Hits	325	Target Neighborhood Hits	126	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	0.000121331 (rank : 93)	NC score	0.442514 (rank : 90)
Query Neighborhood Hits	325	Target Neighborhood Hits	128	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

SYJ2B_HUMAN
θ value	0.000121331 (rank : 94)	NC score	0.747674 (rank : 14)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	158
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

PDLI7_MOUSE
θ value	0.000158464 (rank : 95)	NC score	0.263472 (rank : 160)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	106
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

IL16_HUMAN
θ value	0.00020696 (rank : 96)	NC score	0.627343 (rank : 59)
Query Neighborhood Hits	325	Target Neighborhood Hits	207	Shared Neighborhood Hits	143
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

RHPN1_MOUSE
θ value	0.00035302 (rank : 97)	NC score	0.412831 (rank : 102)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	135
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

IL16_MOUSE
θ value	0.000461057 (rank : 98)	NC score	0.604840 (rank : 66)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	139
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZK4_MOUSE
θ value	0.000461057 (rank : 99)	NC score	0.447491 (rank : 86)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

ARHGC_HUMAN
θ value	0.000602161 (rank : 100)	NC score	0.340572 (rank : 138)
Query Neighborhood Hits	325	Target Neighborhood Hits	351	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LMO7_HUMAN
θ value	0.000602161 (rank : 101)	NC score	0.174465 (rank : 177)
Query Neighborhood Hits	325	Target Neighborhood Hits	507	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LAP2_HUMAN
θ value	0.000786445 (rank : 102)	NC score	0.250803 (rank : 164)
Query Neighborhood Hits	325	Target Neighborhood Hits	499	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDLI7_HUMAN
θ value	0.000786445 (rank : 103)	NC score	0.269172 (rank : 155)
Query Neighborhood Hits	325	Target Neighborhood Hits	547	Shared Neighborhood Hits	144
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

APBA2_HUMAN
θ value	0.00102713 (rank : 104)	NC score	0.412577 (rank : 103)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	154
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.00102713 (rank : 105)	NC score	0.413198 (rank : 101)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	153
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APXL_HUMAN
θ value	0.00102713 (rank : 106)	NC score	0.362199 (rank : 125)
Query Neighborhood Hits	325	Target Neighborhood Hits	553	Shared Neighborhood Hits	118
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

LAP2_MOUSE
θ value	0.00102713 (rank : 107)	NC score	0.240491 (rank : 165)
Query Neighborhood Hits	325	Target Neighborhood Hits	482	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDLI2_MOUSE
θ value	0.00102713 (rank : 108)	NC score	0.450886 (rank : 84)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PTN3_HUMAN
θ value	0.00102713 (rank : 109)	NC score	0.177841 (rank : 176)
Query Neighborhood Hits	325	Target Neighborhood Hits	258	Shared Neighborhood Hits	115
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SYNP2_MOUSE
θ value	0.00102713 (rank : 110)	NC score	0.390637 (rank : 112)
Query Neighborhood Hits	325	Target Neighborhood Hits	252	Shared Neighborhood Hits	133
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

ARHGC_MOUSE
θ value	0.00134147 (rank : 111)	NC score	0.335415 (rank : 142)
Query Neighborhood Hits	325	Target Neighborhood Hits	344	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

K1849_MOUSE
θ value	0.00134147 (rank : 112)	NC score	0.475114 (rank : 79)
Query Neighborhood Hits	325	Target Neighborhood Hits	335	Shared Neighborhood Hits	158
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PAR6A_HUMAN
θ value	0.00134147 (rank : 113)	NC score	0.420916 (rank : 95)
Query Neighborhood Hits	325	Target Neighborhood Hits	119	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	0.00134147 (rank : 114)	NC score	0.422488 (rank : 94)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PDLI5_MOUSE
θ value	0.00134147 (rank : 115)	NC score	0.270889 (rank : 152)
Query Neighborhood Hits	325	Target Neighborhood Hits	287	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SHAN2_HUMAN
θ value	0.00134147 (rank : 116)	NC score	0.353913 (rank : 129)
Query Neighborhood Hits	325	Target Neighborhood Hits	346	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

NEB1_HUMAN
θ value	0.00175202 (rank : 117)	NC score	0.382644 (rank : 114)
Query Neighborhood Hits	325	Target Neighborhood Hits	829	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PDZK4_HUMAN
θ value	0.00175202 (rank : 118)	NC score	0.442862 (rank : 89)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PTN4_HUMAN
θ value	0.00175202 (rank : 119)	NC score	0.179858 (rank : 175)
Query Neighborhood Hits	325	Target Neighborhood Hits	303	Shared Neighborhood Hits	122
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

APBA3_MOUSE
θ value	0.00228821 (rank : 120)	NC score	0.392655 (rank : 111)
Query Neighborhood Hits	325	Target Neighborhood Hits	174	Shared Neighborhood Hits	135
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN2_MOUSE
θ value	0.00228821 (rank : 121)	NC score	0.321981 (rank : 148)
Query Neighborhood Hits	325	Target Neighborhood Hits	446	Shared Neighborhood Hits	135
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

DVL2_MOUSE
θ value	0.00298849 (rank : 122)	NC score	0.370320 (rank : 121)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	125
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MAGD4_HUMAN
θ value	0.00298849 (rank : 123)	NC score	0.038505 (rank : 265)
Query Neighborhood Hits	325	Target Neighborhood Hits	338	Shared Neighborhood Hits	33
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MAST3_HUMAN
θ value	0.00298849 (rank : 124)	NC score	0.068450 (rank : 210)
Query Neighborhood Hits	325	Target Neighborhood Hits	1128	Shared Neighborhood Hits	136
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

SYNP2_HUMAN
θ value	0.00298849 (rank : 125)	NC score	0.339155 (rank : 139)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI1_HUMAN
θ value	0.00390308 (rank : 126)	NC score	0.343413 (rank : 135)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

APBA3_HUMAN
θ value	0.00509761 (rank : 127)	NC score	0.399982 (rank : 104)
Query Neighborhood Hits	325	Target Neighborhood Hits	201	Shared Neighborhood Hits	137
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PDLI3_HUMAN
θ value	0.00509761 (rank : 128)	NC score	0.357829 (rank : 127)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI5_HUMAN
θ value	0.00509761 (rank : 129)	NC score	0.270640 (rank : 153)
Query Neighborhood Hits	325	Target Neighborhood Hits	322	Shared Neighborhood Hits	122
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

APBA1_HUMAN
θ value	0.00665767 (rank : 130)	NC score	0.418170 (rank : 99)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

SRRM2_MOUSE
θ value	0.00665767 (rank : 131)	NC score	0.082097 (rank : 200)
Query Neighborhood Hits	325	Target Neighborhood Hits	1470	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STXB4_HUMAN
θ value	0.00665767 (rank : 132)	NC score	0.337145 (rank : 141)
Query Neighborhood Hits	325	Target Neighborhood Hits	616	Shared Neighborhood Hits	105
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TIAM1_MOUSE
θ value	0.00665767 (rank : 133)	NC score	0.105322 (rank : 187)
Query Neighborhood Hits	325	Target Neighborhood Hits	205	Shared Neighborhood Hits	48
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

K1849_HUMAN
θ value	0.00869519 (rank : 134)	NC score	0.480526 (rank : 78)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	144
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LDB3_HUMAN
θ value	0.00869519 (rank : 135)	NC score	0.274557 (rank : 150)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	131
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	0.00869519 (rank : 136)	NC score	0.274261 (rank : 151)
Query Neighborhood Hits	325	Target Neighborhood Hits	510	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MPP5_HUMAN
θ value	0.00869519 (rank : 137)	NC score	0.396939 (rank : 109)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	133
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.00869519 (rank : 138)	NC score	0.395938 (rank : 110)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PDLI3_MOUSE
θ value	0.00869519 (rank : 139)	NC score	0.340822 (rank : 137)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SDCB1_HUMAN
θ value	0.00869519 (rank : 140)	NC score	0.419889 (rank : 98)
Query Neighborhood Hits	325	Target Neighborhood Hits	150	Shared Neighborhood Hits	143
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

MAST4_HUMAN
θ value	0.0113563 (rank : 141)	NC score	0.074782 (rank : 204)
Query Neighborhood Hits	325	Target Neighborhood Hits	1804	Shared Neighborhood Hits	179
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NEB2_HUMAN
θ value	0.0113563 (rank : 142)	NC score	0.353826 (rank : 130)
Query Neighborhood Hits	325	Target Neighborhood Hits	883	Shared Neighborhood Hits	128
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.0113563 (rank : 143)	NC score	0.349593 (rank : 131)
Query Neighborhood Hits	325	Target Neighborhood Hits	889	Shared Neighborhood Hits	130
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDLI1_MOUSE
θ value	0.0113563 (rank : 144)	NC score	0.344794 (rank : 134)
Query Neighborhood Hits	325	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

RIMS2_HUMAN
θ value	0.0113563 (rank : 145)	NC score	0.216274 (rank : 169)
Query Neighborhood Hits	325	Target Neighborhood Hits	342	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.0113563 (rank : 146)	NC score	0.214324 (rank : 170)
Query Neighborhood Hits	325	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

DVL2_HUMAN
θ value	0.0148317 (rank : 147)	NC score	0.369317 (rank : 122)
Query Neighborhood Hits	325	Target Neighborhood Hits	223	Shared Neighborhood Hits	129
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

LIMK1_HUMAN
θ value	0.0148317 (rank : 148)	NC score	0.040665 (rank : 259)
Query Neighborhood Hits	325	Target Neighborhood Hits	1005	Shared Neighborhood Hits	81
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
θ value	0.0148317 (rank : 149)	NC score	0.038587 (rank : 264)
Query Neighborhood Hits	325	Target Neighborhood Hits	1008	Shared Neighborhood Hits	79
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

PICK1_HUMAN
θ value	0.0148317 (rank : 150)	NC score	0.398710 (rank : 107)
Query Neighborhood Hits	325	Target Neighborhood Hits	132	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

TIAM1_HUMAN
θ value	0.0148317 (rank : 151)	NC score	0.132971 (rank : 180)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

GRASP_MOUSE
θ value	0.0193708 (rank : 152)	NC score	0.432066 (rank : 92)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

KI13B_HUMAN
θ value	0.0193708 (rank : 153)	NC score	0.020350 (rank : 293)
Query Neighborhood Hits	325	Target Neighborhood Hits	492	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PDLI4_HUMAN
θ value	0.0193708 (rank : 154)	NC score	0.338436 (rank : 140)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	113
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	0.0193708 (rank : 155)	NC score	0.342747 (rank : 136)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	112
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SDCB1_MOUSE
θ value	0.0193708 (rank : 156)	NC score	0.420664 (rank : 96)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	135
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

MPP3_HUMAN
θ value	0.0330416 (rank : 157)	NC score	0.378927 (rank : 116)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	126
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	0.0330416 (rank : 158)	NC score	0.381425 (rank : 115)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PDLI2_HUMAN
θ value	0.0330416 (rank : 159)	NC score	0.454727 (rank : 80)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	130
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

NOS1_HUMAN
θ value	0.0431538 (rank : 160)	NC score	0.299943 (rank : 149)
Query Neighborhood Hits	325	Target Neighborhood Hits	218	Shared Neighborhood Hits	138
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

STXB4_MOUSE
θ value	0.0431538 (rank : 161)	NC score	0.330840 (rank : 145)
Query Neighborhood Hits	325	Target Neighborhood Hits	629	Shared Neighborhood Hits	101
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DVL3_HUMAN
θ value	0.0736092 (rank : 162)	NC score	0.375754 (rank : 117)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	121
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.0736092 (rank : 163)	NC score	0.373509 (rank : 119)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

GRASP_HUMAN
θ value	0.0736092 (rank : 164)	NC score	0.430091 (rank : 93)
Query Neighborhood Hits	325	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

MAST1_HUMAN
θ value	0.0736092 (rank : 165)	NC score	0.066369 (rank : 220)
Query Neighborhood Hits	325	Target Neighborhood Hits	1146	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

DVL1_HUMAN
θ value	0.0961366 (rank : 166)	NC score	0.375480 (rank : 118)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	121
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	0.0961366 (rank : 167)	NC score	0.366592 (rank : 123)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

NOS1_MOUSE
θ value	0.0961366 (rank : 168)	NC score	0.256247 (rank : 163)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PRRT3_HUMAN
θ value	0.0961366 (rank : 169)	NC score	0.067221 (rank : 215)
Query Neighborhood Hits	325	Target Neighborhood Hits	998	Shared Neighborhood Hits	82
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

DVL1L_HUMAN
θ value	0.125558 (rank : 170)	NC score	0.359144 (rank : 126)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	116
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

GIPC1_MOUSE
θ value	0.125558 (rank : 171)	NC score	0.231119 (rank : 167)
Query Neighborhood Hits	325	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

MAST2_HUMAN
θ value	0.125558 (rank : 172)	NC score	0.067173 (rank : 216)
Query Neighborhood Hits	325	Target Neighborhood Hits	1189	Shared Neighborhood Hits	135
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TCOF_HUMAN
θ value	0.125558 (rank : 173)	NC score	0.065477 (rank : 223)
Query Neighborhood Hits	325	Target Neighborhood Hits	543	Shared Neighborhood Hits	44
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ZN335_HUMAN
θ value	0.125558 (rank : 174)	NC score	-0.002525 (rank : 351)
Query Neighborhood Hits	325	Target Neighborhood Hits	973	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

GIPC1_HUMAN
θ value	0.163984 (rank : 175)	NC score	0.218542 (rank : 168)
Query Neighborhood Hits	325	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PREX1_HUMAN
θ value	0.163984 (rank : 176)	NC score	0.067683 (rank : 214)
Query Neighborhood Hits	325	Target Neighborhood Hits	177	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PSCBP_MOUSE
θ value	0.163984 (rank : 177)	NC score	0.398043 (rank : 108)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RGS3_MOUSE
θ value	0.163984 (rank : 178)	NC score	0.102120 (rank : 189)
Query Neighborhood Hits	325	Target Neighborhood Hits	1621	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SIPA1_HUMAN
θ value	0.163984 (rank : 179)	NC score	0.066728 (rank : 217)
Query Neighborhood Hits	325	Target Neighborhood Hits	250	Shared Neighborhood Hits	39
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

AFF2_MOUSE
θ value	0.21417 (rank : 180)	NC score	0.039004 (rank : 263)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

BPTF_HUMAN
θ value	0.21417 (rank : 181)	NC score	0.025581 (rank : 284)
Query Neighborhood Hits	325	Target Neighborhood Hits	786	Shared Neighborhood Hits	37
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MAST1_MOUSE
θ value	0.21417 (rank : 182)	NC score	0.066451 (rank : 218)
Query Neighborhood Hits	325	Target Neighborhood Hits	1123	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PICK1_MOUSE
θ value	0.21417 (rank : 183)	NC score	0.386971 (rank : 113)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	123
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

SIPA1_MOUSE
θ value	0.21417 (rank : 184)	NC score	0.052280 (rank : 242)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

CAR11_HUMAN
θ value	0.279714 (rank : 185)	NC score	0.094627 (rank : 196)
Query Neighborhood Hits	325	Target Neighborhood Hits	690	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

MAST2_MOUSE
θ value	0.279714 (rank : 186)	NC score	0.065100 (rank : 226)
Query Neighborhood Hits	325	Target Neighborhood Hits	1110	Shared Neighborhood Hits	131
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PCLO_MOUSE
θ value	0.279714 (rank : 187)	NC score	0.195844 (rank : 173)
Query Neighborhood Hits	325	Target Neighborhood Hits	2275	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PPRB_HUMAN
θ value	0.279714 (rank : 188)	NC score	0.050567 (rank : 247)
Query Neighborhood Hits	325	Target Neighborhood Hits	311	Shared Neighborhood Hits	35
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

TAF9_MOUSE
θ value	0.279714 (rank : 189)	NC score	0.026811 (rank : 280)
Query Neighborhood Hits	325	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TAU_MOUSE
θ value	0.279714 (rank : 190)	NC score	0.046116 (rank : 252)
Query Neighborhood Hits	325	Target Neighborhood Hits	502	Shared Neighborhood Hits	45
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

BAZ2A_HUMAN
θ value	0.365318 (rank : 191)	NC score	0.024972 (rank : 288)
Query Neighborhood Hits	325	Target Neighborhood Hits	780	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

GIPC3_HUMAN
θ value	0.365318 (rank : 192)	NC score	0.132172 (rank : 181)
Query Neighborhood Hits	325	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	0.365318 (rank : 193)	NC score	0.130824 (rank : 183)
Query Neighborhood Hits	325	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

MLL4_HUMAN
θ value	0.365318 (rank : 194)	NC score	0.036567 (rank : 267)
Query Neighborhood Hits	325	Target Neighborhood Hits	722	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HTRA3_MOUSE
θ value	0.47712 (rank : 195)	NC score	0.133419 (rank : 179)
Query Neighborhood Hits	325	Target Neighborhood Hits	156	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

TGON2_HUMAN
θ value	0.47712 (rank : 196)	NC score	0.040327 (rank : 260)
Query Neighborhood Hits	325	Target Neighborhood Hits	1037	Shared Neighborhood Hits	67
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BCOR_HUMAN
θ value	0.62314 (rank : 197)	NC score	0.022128 (rank : 291)
Query Neighborhood Hits	325	Target Neighborhood Hits	609	Shared Neighborhood Hits	33
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

HTRA3_HUMAN
θ value	0.62314 (rank : 198)	NC score	0.124564 (rank : 185)
Query Neighborhood Hits	325	Target Neighborhood Hits	152	Shared Neighborhood Hits	64
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

SDCB2_MOUSE
θ value	0.62314 (rank : 199)	NC score	0.355765 (rank : 128)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SOX30_MOUSE
θ value	0.62314 (rank : 200)	NC score	0.019826 (rank : 294)
Query Neighborhood Hits	325	Target Neighborhood Hits	374	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TLE1_MOUSE
θ value	0.62314 (rank : 201)	NC score	0.017779 (rank : 301)
Query Neighborhood Hits	325	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

EM55_HUMAN
θ value	0.813845 (rank : 202)	NC score	0.328876 (rank : 146)
Query Neighborhood Hits	325	Target Neighborhood Hits	228	Shared Neighborhood Hits	119
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	0.813845 (rank : 203)	NC score	0.327977 (rank : 147)
Query Neighborhood Hits	325	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GSCR1_HUMAN
θ value	0.813845 (rank : 204)	NC score	0.068360 (rank : 211)
Query Neighborhood Hits	325	Target Neighborhood Hits	674	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PER3_HUMAN
θ value	0.813845 (rank : 205)	NC score	0.033719 (rank : 273)
Query Neighborhood Hits	325	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ZN217_HUMAN
θ value	0.813845 (rank : 206)	NC score	-0.003108 (rank : 353)
Query Neighborhood Hits	325	Target Neighborhood Hits	905	Shared Neighborhood Hits	24
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

AXN2_HUMAN
θ value	1.06291 (rank : 207)	NC score	0.030960 (rank : 276)
Query Neighborhood Hits	325	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

ENAH_HUMAN
θ value	1.06291 (rank : 208)	NC score	0.030177 (rank : 277)
Query Neighborhood Hits	325	Target Neighborhood Hits	784	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

HTRA1_HUMAN
θ value	1.06291 (rank : 209)	NC score	0.096568 (rank : 193)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA4_HUMAN
θ value	1.06291 (rank : 210)	NC score	0.085575 (rank : 199)
Query Neighborhood Hits	325	Target Neighborhood Hits	119	Shared Neighborhood Hits	44
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

PAX3_HUMAN
θ value	1.06291 (rank : 211)	NC score	0.001172 (rank : 346)
Query Neighborhood Hits	325	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PDZD8_HUMAN
θ value	1.06291 (rank : 212)	NC score	0.140675 (rank : 178)
Query Neighborhood Hits	325	Target Neighborhood Hits	185	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PHLB1_HUMAN
θ value	1.06291 (rank : 213)	NC score	0.026124 (rank : 282)
Query Neighborhood Hits	325	Target Neighborhood Hits	1038	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRR12_HUMAN
θ value	1.06291 (rank : 214)	NC score	0.059627 (rank : 233)
Query Neighborhood Hits	325	Target Neighborhood Hits	460	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SDCB2_HUMAN
θ value	1.06291 (rank : 215)	NC score	0.334013 (rank : 143)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

BCL9_HUMAN
θ value	1.38821 (rank : 216)	NC score	0.057734 (rank : 237)
Query Neighborhood Hits	325	Target Neighborhood Hits	1008	Shared Neighborhood Hits	82
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EAF1_MOUSE
θ value	1.38821 (rank : 217)	NC score	0.068043 (rank : 213)
Query Neighborhood Hits	325	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

GIT1_HUMAN
θ value	1.38821 (rank : 218)	NC score	0.017854 (rank : 300)
Query Neighborhood Hits	325	Target Neighborhood Hits	336	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	1.38821 (rank : 219)	NC score	0.016989 (rank : 303)
Query Neighborhood Hits	325	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

HTRA1_MOUSE
θ value	1.38821 (rank : 220)	NC score	0.094110 (rank : 197)
Query Neighborhood Hits	325	Target Neighborhood Hits	140	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

MPP4_HUMAN
θ value	1.38821 (rank : 221)	NC score	0.399498 (rank : 106)
Query Neighborhood Hits	325	Target Neighborhood Hits	205	Shared Neighborhood Hits	135
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NCOA6_MOUSE
θ value	1.38821 (rank : 222)	NC score	0.033777 (rank : 272)
Query Neighborhood Hits	325	Target Neighborhood Hits	1076	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TCGAP_HUMAN
θ value	1.38821 (rank : 223)	NC score	0.029310 (rank : 278)
Query Neighborhood Hits	325	Target Neighborhood Hits	872	Shared Neighborhood Hits	72
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCOF_MOUSE
θ value	1.38821 (rank : 224)	NC score	0.073911 (rank : 206)
Query Neighborhood Hits	325	Target Neighborhood Hits	471	Shared Neighborhood Hits	42
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TLE4_MOUSE
θ value	1.38821 (rank : 225)	NC score	0.015173 (rank : 309)
Query Neighborhood Hits	325	Target Neighborhood Hits	482	Shared Neighborhood Hits	23
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

EAF1_HUMAN
θ value	1.81305 (rank : 226)	NC score	0.066387 (rank : 219)
Query Neighborhood Hits	325	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

PGCB_HUMAN
θ value	1.81305 (rank : 227)	NC score	0.004938 (rank : 338)
Query Neighborhood Hits	325	Target Neighborhood Hits	478	Shared Neighborhood Hits	19
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PHC2_MOUSE
θ value	1.81305 (rank : 228)	NC score	0.025365 (rank : 286)
Query Neighborhood Hits	325	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

ROBO2_MOUSE
θ value	1.81305 (rank : 229)	NC score	0.000742 (rank : 348)
Query Neighborhood Hits	325	Target Neighborhood Hits	504	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO3_MOUSE
θ value	1.81305 (rank : 230)	NC score	0.003694 (rank : 340)
Query Neighborhood Hits	325	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SC24C_HUMAN
θ value	1.81305 (rank : 231)	NC score	0.042445 (rank : 256)
Query Neighborhood Hits	325	Target Neighborhood Hits	662	Shared Neighborhood Hits	59
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TLE4_HUMAN
θ value	1.81305 (rank : 232)	NC score	0.014803 (rank : 310)
Query Neighborhood Hits	325	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

ANK2_HUMAN
θ value	2.36792 (rank : 233)	NC score	0.022125 (rank : 292)
Query Neighborhood Hits	325	Target Neighborhood Hits	1615	Shared Neighborhood Hits	88
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

EMID2_MOUSE
θ value	2.36792 (rank : 234)	NC score	0.015310 (rank : 308)
Query Neighborhood Hits	325	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

FOXN4_HUMAN
θ value	2.36792 (rank : 235)	NC score	0.012355 (rank : 317)
Query Neighborhood Hits	325	Target Neighborhood Hits	248	Shared Neighborhood Hits	16
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

GLI1_HUMAN
θ value	2.36792 (rank : 236)	NC score	-0.004115 (rank : 355)
Query Neighborhood Hits	325	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

RANB9_HUMAN
θ value	2.36792 (rank : 237)	NC score	0.023547 (rank : 289)
Query Neighborhood Hits	325	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

SL9A5_HUMAN
θ value	2.36792 (rank : 238)	NC score	0.010028 (rank : 324)
Query Neighborhood Hits	325	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q14940, Q9Y626	Gene names	SLC9A5, NHE5
Domain Architecture
Description	Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5).

SRBS1_HUMAN
θ value	2.36792 (rank : 239)	NC score	0.009885 (rank : 325)
Query Neighborhood Hits	325	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

FBX40_MOUSE
θ value	3.0926 (rank : 240)	NC score	0.011538 (rank : 318)
Query Neighborhood Hits	325	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P62932	Gene names	Fbxo40
Domain Architecture	No domain graphic available
Description	F-box only protein 40.

GIPC2_MOUSE
θ value	3.0926 (rank : 241)	NC score	0.131929 (rank : 182)
Query Neighborhood Hits	325	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GLI2_HUMAN
θ value	3.0926 (rank : 242)	NC score	-0.005061 (rank : 356)
Query Neighborhood Hits	325	Target Neighborhood Hits	971	Shared Neighborhood Hits	31
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

MLL3_HUMAN
θ value	3.0926 (rank : 243)	NC score	0.042451 (rank : 255)
Query Neighborhood Hits	325	Target Neighborhood Hits	1644	Shared Neighborhood Hits	102
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MY18A_MOUSE
θ value	3.0926 (rank : 244)	NC score	0.066306 (rank : 221)
Query Neighborhood Hits	325	Target Neighborhood Hits	1989	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RAB5A_HUMAN
θ value	3.0926 (rank : 245)	NC score	-0.003434 (rank : 354)
Query Neighborhood Hits	325	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	P20339	Gene names	RAB5A, RAB5
Domain Architecture
Description	Ras-related protein Rab-5A.

RHPN2_MOUSE
θ value	3.0926 (rank : 246)	NC score	0.115937 (rank : 186)
Query Neighborhood Hits	325	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

ZN687_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.009763 (rank : 326)
Query Neighborhood Hits	325	Target Neighborhood Hits	1244	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AKA10_MOUSE
θ value	4.03905 (rank : 248)	NC score	0.023352 (rank : 290)
Query Neighborhood Hits	325	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

BAT2_HUMAN
θ value	4.03905 (rank : 249)	NC score	0.064497 (rank : 228)
Query Neighborhood Hits	325	Target Neighborhood Hits	931	Shared Neighborhood Hits	85
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	4.03905 (rank : 250)	NC score	0.049425 (rank : 249)
Query Neighborhood Hits	325	Target Neighborhood Hits	947	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
θ value	4.03905 (rank : 251)	NC score	0.044880 (rank : 253)
Query Neighborhood Hits	325	Target Neighborhood Hits	1537	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CBL_MOUSE
θ value	4.03905 (rank : 252)	NC score	0.028697 (rank : 279)
Query Neighborhood Hits	325	Target Neighborhood Hits	426	Shared Neighborhood Hits	36
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

EAN57_HUMAN
θ value	4.03905 (rank : 253)	NC score	0.026247 (rank : 281)
Query Neighborhood Hits	325	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

IF39_HUMAN
θ value	4.03905 (rank : 254)	NC score	0.016492 (rank : 304)
Query Neighborhood Hits	325	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

PER1_MOUSE
θ value	4.03905 (rank : 255)	NC score	0.025346 (rank : 287)
Query Neighborhood Hits	325	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PSMD9_HUMAN
θ value	4.03905 (rank : 256)	NC score	0.101936 (rank : 191)
Query Neighborhood Hits	325	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

SI1L1_HUMAN
θ value	4.03905 (rank : 257)	NC score	0.070884 (rank : 209)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SON_HUMAN
θ value	4.03905 (rank : 258)	NC score	0.036293 (rank : 268)
Query Neighborhood Hits	325	Target Neighborhood Hits	1568	Shared Neighborhood Hits	98
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SOS2_HUMAN
θ value	4.03905 (rank : 259)	NC score	0.034259 (rank : 271)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	21
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SSPO_MOUSE
θ value	4.03905 (rank : 260)	NC score	-0.001984 (rank : 350)
Query Neighborhood Hits	325	Target Neighborhood Hits	800	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TITIN_HUMAN
θ value	4.03905 (rank : 261)	NC score	0.002397 (rank : 342)
Query Neighborhood Hits	325	Target Neighborhood Hits	2923	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TTLL5_HUMAN
θ value	4.03905 (rank : 262)	NC score	0.009138 (rank : 330)
Query Neighborhood Hits	325	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

ZN687_MOUSE
θ value	4.03905 (rank : 263)	NC score	0.000390 (rank : 349)
Query Neighborhood Hits	325	Target Neighborhood Hits	913	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ABLM1_HUMAN
θ value	5.27518 (rank : 264)	NC score	0.032754 (rank : 274)
Query Neighborhood Hits	325	Target Neighborhood Hits	387	Shared Neighborhood Hits	24
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

BAG3_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.049289 (rank : 250)
Query Neighborhood Hits	325	Target Neighborhood Hits	314	Shared Neighborhood Hits	39
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CSKP_HUMAN
θ value	5.27518 (rank : 266)	NC score	0.104675 (rank : 188)
Query Neighborhood Hits	325	Target Neighborhood Hits	1022	Shared Neighborhood Hits	119
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	5.27518 (rank : 267)	NC score	0.102004 (rank : 190)
Query Neighborhood Hits	325	Target Neighborhood Hits	1027	Shared Neighborhood Hits	119
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CTDP1_HUMAN
θ value	5.27518 (rank : 268)	NC score	0.035080 (rank : 270)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

ENAH_MOUSE
θ value	5.27518 (rank : 269)	NC score	0.039496 (rank : 262)
Query Neighborhood Hits	325	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

LTB1L_HUMAN
θ value	5.27518 (rank : 270)	NC score	-0.002672 (rank : 352)
Query Neighborhood Hits	325	Target Neighborhood Hits	553	Shared Neighborhood Hits	15
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PRB3_HUMAN
θ value	5.27518 (rank : 271)	NC score	0.040013 (rank : 261)
Query Neighborhood Hits	325	Target Neighborhood Hits	318	Shared Neighborhood Hits	31
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SI1L1_MOUSE
θ value	5.27518 (rank : 272)	NC score	0.068309 (rank : 212)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L2_HUMAN
θ value	5.27518 (rank : 273)	NC score	0.076326 (rank : 201)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	5.27518 (rank : 274)	NC score	0.074623 (rank : 205)
Query Neighborhood Hits	325	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SYN1_MOUSE
θ value	5.27518 (rank : 275)	NC score	0.035771 (rank : 269)
Query Neighborhood Hits	325	Target Neighborhood Hits	363	Shared Neighborhood Hits	38
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAB3_MOUSE
θ value	5.27518 (rank : 276)	NC score	0.025774 (rank : 283)
Query Neighborhood Hits	325	Target Neighborhood Hits	273	Shared Neighborhood Hits	38
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TATD2_HUMAN
θ value	5.27518 (rank : 277)	NC score	0.015908 (rank : 305)
Query Neighborhood Hits	325	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

TLE3_HUMAN
θ value	5.27518 (rank : 278)	NC score	0.014062 (rank : 312)
Query Neighborhood Hits	325	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

ASPP1_HUMAN
θ value	6.88961 (rank : 279)	NC score	0.015643 (rank : 307)
Query Neighborhood Hits	325	Target Neighborhood Hits	956	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATF7_HUMAN
θ value	6.88961 (rank : 280)	NC score	0.008542 (rank : 332)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BRD8_MOUSE
θ value	6.88961 (rank : 281)	NC score	0.019182 (rank : 296)
Query Neighborhood Hits	325	Target Neighborhood Hits	422	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CAR14_MOUSE
θ value	6.88961 (rank : 282)	NC score	0.059066 (rank : 234)
Query Neighborhood Hits	325	Target Neighborhood Hits	526	Shared Neighborhood Hits	32
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CO4A5_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.015891 (rank : 306)
Query Neighborhood Hits	325	Target Neighborhood Hits	383	Shared Neighborhood Hits	30
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

EP400_HUMAN
θ value	6.88961 (rank : 284)	NC score	0.013565 (rank : 314)
Query Neighborhood Hits	325	Target Neighborhood Hits	556	Shared Neighborhood Hits	39
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GATA3_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.019035 (rank : 297)
Query Neighborhood Hits	325	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P23771, Q96J16	Gene names	GATA3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

GIPR_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.001149 (rank : 347)
Query Neighborhood Hits	325	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

HSF1_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.010511 (rank : 323)
Query Neighborhood Hits	325	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

K1543_MOUSE
θ value	6.88961 (rank : 288)	NC score	0.037481 (rank : 266)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	56
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LRC25_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.011239 (rank : 319)
Query Neighborhood Hits	325	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N386, Q8N9A5	Gene names	LRRC25, MAPA
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 25 precursor (Monocyte and plasmacytoid-activated protein).

MPP4_MOUSE
θ value	6.88961 (rank : 290)	NC score	0.348236 (rank : 132)
Query Neighborhood Hits	325	Target Neighborhood Hits	188	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NOL11_HUMAN
θ value	6.88961 (rank : 291)	NC score	0.014289 (rank : 311)
Query Neighborhood Hits	325	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8H0, Q7L5S1, Q9UG18	Gene names	NOL11
Domain Architecture	No domain graphic available
Description	Nucleolar protein 11.

NPAS4_MOUSE
θ value	6.88961 (rank : 292)	NC score	0.012731 (rank : 315)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PAF49_MOUSE
θ value	6.88961 (rank : 293)	NC score	0.018865 (rank : 298)
Query Neighborhood Hits	325	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

PO6F2_HUMAN
θ value	6.88961 (rank : 294)	NC score	0.017037 (rank : 302)
Query Neighborhood Hits	325	Target Neighborhood Hits	618	Shared Neighborhood Hits	35
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PSCBP_HUMAN
θ value	6.88961 (rank : 295)	NC score	0.346320 (rank : 133)
Query Neighborhood Hits	325	Target Neighborhood Hits	123	Shared Neighborhood Hits	115
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RUSC1_MOUSE
θ value	6.88961 (rank : 296)	NC score	0.010928 (rank : 321)
Query Neighborhood Hits	325	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

RXRB_HUMAN
θ value	6.88961 (rank : 297)	NC score	0.002355 (rank : 343)
Query Neighborhood Hits	325	Target Neighborhood Hits	280	Shared Neighborhood Hits	20
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SPIB_MOUSE
θ value	6.88961 (rank : 298)	NC score	0.005491 (rank : 337)
Query Neighborhood Hits	325	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

TCF19_MOUSE
θ value	6.88961 (rank : 299)	NC score	0.010792 (rank : 322)
Query Neighborhood Hits	325	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

WASIP_HUMAN
θ value	6.88961 (rank : 300)	NC score	0.046598 (rank : 251)
Query Neighborhood Hits	325	Target Neighborhood Hits	458	Shared Neighborhood Hits	47
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

AP2A2_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.003174 (rank : 341)
Query Neighborhood Hits	325	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

CO9A2_MOUSE
θ value	8.99809 (rank : 302)	NC score	0.009398 (rank : 327)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CPSF6_HUMAN
θ value	8.99809 (rank : 303)	NC score	0.040740 (rank : 258)
Query Neighborhood Hits	325	Target Neighborhood Hits	359	Shared Neighborhood Hits	36
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	8.99809 (rank : 304)	NC score	0.041774 (rank : 257)
Query Neighborhood Hits	325	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

ELL_MOUSE
θ value	8.99809 (rank : 305)	NC score	0.011116 (rank : 320)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ESAM_MOUSE
θ value	8.99809 (rank : 306)	NC score	0.003784 (rank : 339)
Query Neighborhood Hits	325	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

G3BP_MOUSE
θ value	8.99809 (rank : 307)	NC score	0.006018 (rank : 336)
Query Neighborhood Hits	325	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GATA3_MOUSE
θ value	8.99809 (rank : 308)	NC score	0.017962 (rank : 299)
Query Neighborhood Hits	325	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	P23772	Gene names	Gata3, Gata-3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

GIPC2_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.183086 (rank : 174)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

ICB1_MOUSE
θ value	8.99809 (rank : 310)	NC score	0.008368 (rank : 333)
Query Neighborhood Hits	325	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

MAGB6_HUMAN
θ value	8.99809 (rank : 311)	NC score	0.009360 (rank : 328)
Query Neighborhood Hits	325	Target Neighborhood Hits	184	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

PCLO_HUMAN
θ value	8.99809 (rank : 312)	NC score	0.050902 (rank : 245)
Query Neighborhood Hits	325	Target Neighborhood Hits	2046	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PER1_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.025436 (rank : 285)
Query Neighborhood Hits	325	Target Neighborhood Hits	215	Shared Neighborhood Hits	33
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PHAR3_MOUSE
θ value	8.99809 (rank : 314)	NC score	0.009188 (rank : 329)
Query Neighborhood Hits	325	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PIGG_HUMAN
θ value	8.99809 (rank : 315)	NC score	0.007976 (rank : 334)
Query Neighborhood Hits	325	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

PPRB_MOUSE
θ value	8.99809 (rank : 316)	NC score	0.044174 (rank : 254)
Query Neighborhood Hits	325	Target Neighborhood Hits	354	Shared Neighborhood Hits	43
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RERE_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.031676 (rank : 275)
Query Neighborhood Hits	325	Target Neighborhood Hits	779	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RGS3_HUMAN
θ value	8.99809 (rank : 318)	NC score	0.099092 (rank : 192)
Query Neighborhood Hits	325	Target Neighborhood Hits	1375	Shared Neighborhood Hits	137
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SC6A5_MOUSE
θ value	8.99809 (rank : 319)	NC score	0.001766 (rank : 345)
Query Neighborhood Hits	325	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

SLIK1_MOUSE
θ value	8.99809 (rank : 320)	NC score	0.012500 (rank : 316)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

STAU2_HUMAN
θ value	8.99809 (rank : 321)	NC score	0.008618 (rank : 331)
Query Neighborhood Hits	325	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_MOUSE
θ value	8.99809 (rank : 322)	NC score	0.007960 (rank : 335)
Query Neighborhood Hits	325	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

TACC1_HUMAN
θ value	8.99809 (rank : 323)	NC score	0.002182 (rank : 344)
Query Neighborhood Hits	325	Target Neighborhood Hits	597	Shared Neighborhood Hits	16
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC3_HUMAN
θ value	8.99809 (rank : 324)	NC score	0.019341 (rank : 295)
Query Neighborhood Hits	325	Target Neighborhood Hits	779	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TIF1G_MOUSE
θ value	8.99809 (rank : 325)	NC score	0.013650 (rank : 313)
Query Neighborhood Hits	325	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CAR14_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.065613 (rank : 222)
Query Neighborhood Hits	325	Target Neighborhood Hits	449	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CNKR2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.094831 (rank : 195)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.094865 (rank : 194)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

HTRA2_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.053595 (rank : 239)
Query Neighborhood Hits	325	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

KGUA_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.197561 (rank : 172)
Query Neighborhood Hits	325	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.199649 (rank : 171)
Query Neighborhood Hits	325	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LPP_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.053356 (rank : 240)
Query Neighborhood Hits	325	Target Neighborhood Hits	775	Shared Neighborhood Hits	77
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LRRC1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.061531 (rank : 231)
Query Neighborhood Hits	325	Target Neighborhood Hits	282	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.061864 (rank : 230)
Query Neighborhood Hits	325	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

MPP2_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.264092 (rank : 159)
Query Neighborhood Hits	325	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.268132 (rank : 156)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.260230 (rank : 162)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.264626 (rank : 157)
Query Neighborhood Hits	325	Target Neighborhood Hits	187	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MUC7_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.064937 (rank : 227)
Query Neighborhood Hits	325	Target Neighborhood Hits	538	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MY18A_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.060015 (rank : 232)
Query Neighborhood Hits	325	Target Neighborhood Hits	1929	Shared Neighborhood Hits	149
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NACAM_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.053102 (rank : 241)
Query Neighborhood Hits	325	Target Neighborhood Hits	1866	Shared Neighborhood Hits	120
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PDZD6_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.127050 (rank : 184)
Query Neighborhood Hits	325	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PRAX_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.065205 (rank : 225)
Query Neighborhood Hits	325	Target Neighborhood Hits	215	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.087992 (rank : 198)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRB4S_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.056755 (rank : 238)
Query Neighborhood Hits	325	Target Neighborhood Hits	330	Shared Neighborhood Hits	30
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PSMD9_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.071564 (rank : 207)
Query Neighborhood Hits	325	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PTN23_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.057837 (rank : 236)
Query Neighborhood Hits	325	Target Neighborhood Hits	726	Shared Neighborhood Hits	60
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RHPN2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.064367 (rank : 229)
Query Neighborhood Hits	325	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RNF41_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.075447 (rank : 203)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.075610 (rank : 202)
Query Neighborhood Hits	325	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SAV1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.051097 (rank : 243)
Query Neighborhood Hits	325	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.051060 (rank : 244)
Query Neighborhood Hits	325	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SI1L3_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.058534 (rank : 235)
Query Neighborhood Hits	325	Target Neighborhood Hits	305	Shared Neighborhood Hits	56
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SRRM1_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.050807 (rank : 246)
Query Neighborhood Hits	325	Target Neighborhood Hits	966	Shared Neighborhood Hits	79
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.065339 (rank : 224)
Query Neighborhood Hits	325	Target Neighborhood Hits	1296	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNPO_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.050145 (rank : 248)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

Hits sorted by NC score

WHRN_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	325
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.973602 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	325	Target Neighborhood Hits	412	Shared Neighborhood Hits	247
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD7_HUMAN
NC score	0.907071 (rank : 3)	θ value	3.61106e-41 (rank : 3)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	177
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

USH1C_HUMAN
NC score	0.868187 (rank : 4)	θ value	4.72714e-33 (rank : 4)
Query Neighborhood Hits	325	Target Neighborhood Hits	327	Shared Neighborhood Hits	198
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
NC score	0.816638 (rank : 5)	θ value	4.00176e-32 (rank : 5)
Query Neighborhood Hits	325	Target Neighborhood Hits	557	Shared Neighborhood Hits	211
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDZ11_HUMAN
NC score	0.775959 (rank : 6)	θ value	5.62301e-10 (rank : 34)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	155
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
NC score	0.772634 (rank : 7)	θ value	5.62301e-10 (rank : 35)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LIN7B_HUMAN
NC score	0.762593 (rank : 8)	θ value	1.25267e-09 (rank : 37)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	186
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.760347 (rank : 9)	θ value	1.63604e-09 (rank : 41)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	186
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_MOUSE
NC score	0.759257 (rank : 10)	θ value	1.63604e-09 (rank : 40)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	183
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.759043 (rank : 11)	θ value	1.63604e-09 (rank : 39)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	183
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7C_HUMAN
NC score	0.757795 (rank : 12)	θ value	3.64472e-09 (rank : 43)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.757795 (rank : 13)	θ value	3.64472e-09 (rank : 44)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SYJ2B_HUMAN
NC score	0.747674 (rank : 14)	θ value	0.000121331 (rank : 94)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	158
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

INADL_MOUSE
NC score	0.733128 (rank : 15)	θ value	3.89403e-11 (rank : 27)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	199
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_MOUSE
NC score	0.729943 (rank : 16)	θ value	3.52202e-12 (rank : 20)
Query Neighborhood Hits	325	Target Neighborhood Hits	298	Shared Neighborhood Hits	196
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.726481 (rank : 17)	θ value	1.74796e-11 (rank : 25)
Query Neighborhood Hits	325	Target Neighborhood Hits	261	Shared Neighborhood Hits	197
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

INADL_HUMAN
NC score	0.726439 (rank : 18)	θ value	1.47974e-10 (rank : 28)
Query Neighborhood Hits	325	Target Neighborhood Hits	260	Shared Neighborhood Hits	186
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

NHERF_MOUSE
NC score	0.717456 (rank : 19)	θ value	1.33837e-11 (rank : 23)
Query Neighborhood Hits	325	Target Neighborhood Hits	195	Shared Neighborhood Hits	170
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_MOUSE
NC score	0.713834 (rank : 20)	θ value	1.9326e-10 (rank : 30)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	168
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHERF_HUMAN
NC score	0.710802 (rank : 21)	θ value	1.58096e-12 (rank : 18)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	168
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.709253 (rank : 22)	θ value	1.74796e-11 (rank : 26)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
NC score	0.704323 (rank : 23)	θ value	6.00763e-12 (rank : 21)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	182
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

TX1B3_HUMAN
NC score	0.700159 (rank : 24)	θ value	2.44474e-05 (rank : 81)
Query Neighborhood Hits	325	Target Neighborhood Hits	161	Shared Neighborhood Hits	159
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
NC score	0.697981 (rank : 25)	θ value	2.44474e-05 (rank : 82)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	156
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PDZD1_HUMAN
NC score	0.695197 (rank : 26)	θ value	5.81887e-07 (rank : 61)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	169
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

GOPC_MOUSE
NC score	0.692194 (rank : 27)	θ value	2.52405e-10 (rank : 32)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

DLG4_MOUSE
NC score	0.691286 (rank : 28)	θ value	2.35696e-16 (rank : 6)
Query Neighborhood Hits	325	Target Neighborhood Hits	282	Shared Neighborhood Hits	181
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.689806 (rank : 29)	θ value	5.25075e-16 (rank : 7)
Query Neighborhood Hits	325	Target Neighborhood Hits	286	Shared Neighborhood Hits	179
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GOPC_HUMAN
NC score	0.682170 (rank : 30)	θ value	2.52405e-10 (rank : 31)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

DLG3_MOUSE
NC score	0.679441 (rank : 31)	θ value	1.68911e-14 (rank : 12)
Query Neighborhood Hits	325	Target Neighborhood Hits	274	Shared Neighborhood Hits	178
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.677842 (rank : 32)	θ value	1.68911e-14 (rank : 11)
Query Neighborhood Hits	325	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
NC score	0.675176 (rank : 33)	θ value	6.85773e-16 (rank : 8)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	172
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
NC score	0.673038 (rank : 34)	θ value	6.85773e-16 (rank : 9)
Query Neighborhood Hits	325	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

PAR3L_HUMAN
NC score	0.670370 (rank : 35)	θ value	1.80886e-08 (rank : 51)
Query Neighborhood Hits	325	Target Neighborhood Hits	297	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

DLG2_HUMAN
NC score	0.666189 (rank : 36)	θ value	6.41864e-14 (rank : 14)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	176
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
NC score	0.665778 (rank : 37)	θ value	8.38298e-14 (rank : 15)
Query Neighborhood Hits	325	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PDZD3_HUMAN
NC score	0.665271 (rank : 38)	θ value	2.36244e-08 (rank : 55)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	165
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

GRIP2_HUMAN
NC score	0.661084 (rank : 39)	θ value	3.41135e-07 (rank : 58)
Query Neighborhood Hits	325	Target Neighborhood Hits	256	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

MAGI1_HUMAN
NC score	0.660517 (rank : 40)	θ value	3.29651e-10 (rank : 33)
Query Neighborhood Hits	325	Target Neighborhood Hits	388	Shared Neighborhood Hits	198
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.660291 (rank : 41)	θ value	1.74796e-11 (rank : 24)
Query Neighborhood Hits	325	Target Neighborhood Hits	403	Shared Neighborhood Hits	203
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PDZD2_HUMAN
NC score	0.656325 (rank : 42)	θ value	1.80886e-08 (rank : 52)
Query Neighborhood Hits	325	Target Neighborhood Hits	772	Shared Neighborhood Hits	218
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GRIP1_MOUSE
NC score	0.655532 (rank : 43)	θ value	3.77169e-06 (rank : 71)
Query Neighborhood Hits	325	Target Neighborhood Hits	241	Shared Neighborhood Hits	194
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PARD3_MOUSE
NC score	0.655119 (rank : 44)	θ value	4.45536e-07 (rank : 59)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	171
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

GRIP1_HUMAN
NC score	0.655109 (rank : 45)	θ value	3.77169e-06 (rank : 70)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PARD3_HUMAN
NC score	0.651042 (rank : 46)	θ value	3.77169e-06 (rank : 72)
Query Neighborhood Hits	325	Target Neighborhood Hits	312	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LNX2_MOUSE
NC score	0.650702 (rank : 47)	θ value	4.0297e-08 (rank : 57)
Query Neighborhood Hits	325	Target Neighborhood Hits	407	Shared Neighborhood Hits	180
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

SNTG2_HUMAN
NC score	0.648171 (rank : 48)	θ value	1.69304e-06 (rank : 67)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	177
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTB2_MOUSE
NC score	0.647434 (rank : 49)	θ value	4.76016e-09 (rank : 45)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	160
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_HUMAN
NC score	0.646363 (rank : 50)	θ value	1.38499e-08 (rank : 48)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LNX1_MOUSE
NC score	0.645794 (rank : 51)	θ value	1.9326e-10 (rank : 29)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	177
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
NC score	0.640723 (rank : 52)	θ value	3.08544e-08 (rank : 56)
Query Neighborhood Hits	325	Target Neighborhood Hits	389	Shared Neighborhood Hits	179
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PDZD3_MOUSE
NC score	0.638602 (rank : 53)	θ value	4.45536e-07 (rank : 60)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	163
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SNTA1_HUMAN
NC score	0.635390 (rank : 54)	θ value	1.80886e-08 (rank : 53)
Query Neighborhood Hits	325	Target Neighborhood Hits	186	Shared Neighborhood Hits	167
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LNX1_HUMAN
NC score	0.635335 (rank : 55)	θ value	9.59137e-10 (rank : 36)
Query Neighborhood Hits	325	Target Neighborhood Hits	379	Shared Neighborhood Hits	172
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAGI2_HUMAN
NC score	0.632943 (rank : 56)	θ value	1.80886e-08 (rank : 50)
Query Neighborhood Hits	325	Target Neighborhood Hits	373	Shared Neighborhood Hits	193
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

ZO3_MOUSE
NC score	0.630840 (rank : 57)	θ value	2.79066e-09 (rank : 42)
Query Neighborhood Hits	325	Target Neighborhood Hits	224	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

MAGI2_MOUSE
NC score	0.630325 (rank : 58)	θ value	8.11959e-09 (rank : 46)
Query Neighborhood Hits	325	Target Neighborhood Hits	370	Shared Neighborhood Hits	197
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

IL16_HUMAN
NC score	0.627343 (rank : 59)	θ value	0.00020696 (rank : 96)
Query Neighborhood Hits	325	Target Neighborhood Hits	207	Shared Neighborhood Hits	143
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTA1_MOUSE
NC score	0.626802 (rank : 60)	θ value	1.80886e-08 (rank : 54)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	158
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTG2_MOUSE
NC score	0.623411 (rank : 61)	θ value	1.29631e-06 (rank : 66)
Query Neighborhood Hits	325	Target Neighborhood Hits	176	Shared Neighborhood Hits	164
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG1_MOUSE
NC score	0.616603 (rank : 62)	θ value	4.92598e-06 (rank : 74)
Query Neighborhood Hits	325	Target Neighborhood Hits	179	Shared Neighborhood Hits	168
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.615741 (rank : 63)	θ value	3.77169e-06 (rank : 73)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZO3_HUMAN
NC score	0.612429 (rank : 64)	θ value	1.38499e-08 (rank : 49)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTB1_HUMAN
NC score	0.605230 (rank : 65)	θ value	7.59969e-07 (rank : 62)
Query Neighborhood Hits	325	Target Neighborhood Hits	157	Shared Neighborhood Hits	150
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

IL16_MOUSE
NC score	0.604840 (rank : 66)	θ value	0.000461057 (rank : 98)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	139
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTB1_MOUSE
NC score	0.603931 (rank : 67)	θ value	7.59969e-07 (rank : 63)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	147
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PZRN3_MOUSE
NC score	0.589921 (rank : 68)	θ value	1.2105e-12 (rank : 17)
Query Neighborhood Hits	325	Target Neighborhood Hits	447	Shared Neighborhood Hits	162
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.584973 (rank : 69)	θ value	1.58096e-12 (rank : 19)
Query Neighborhood Hits	325	Target Neighborhood Hits	461	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
NC score	0.576748 (rank : 70)	θ value	2.88788e-06 (rank : 69)
Query Neighborhood Hits	325	Target Neighborhood Hits	438	Shared Neighborhood Hits	155
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO2_HUMAN
NC score	0.562561 (rank : 71)	θ value	9.92553e-07 (rank : 64)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
NC score	0.561607 (rank : 72)	θ value	9.92553e-07 (rank : 65)
Query Neighborhood Hits	325	Target Neighborhood Hits	296	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_MOUSE
NC score	0.558326 (rank : 73)	θ value	6.43352e-06 (rank : 77)
Query Neighborhood Hits	325	Target Neighborhood Hits	453	Shared Neighborhood Hits	190
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
NC score	0.549991 (rank : 74)	θ value	6.43352e-06 (rank : 76)
Query Neighborhood Hits	325	Target Neighborhood Hits	474	Shared Neighborhood Hits	187
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RPGF6_HUMAN
NC score	0.509514 (rank : 75)	θ value	7.58209e-15 (rank : 10)
Query Neighborhood Hits	325	Target Neighborhood Hits	266	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

LAP4_HUMAN
NC score	0.501145 (rank : 76)	θ value	1.42992e-13 (rank : 16)
Query Neighborhood Hits	325	Target Neighborhood Hits	608	Shared Neighborhood Hits	206
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.495438 (rank : 77)	θ value	1.68911e-14 (rank : 13)
Query Neighborhood Hits	325	Target Neighborhood Hits	590	Shared Neighborhood Hits	205
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

K1849_HUMAN
NC score	0.480526 (rank : 78)	θ value	0.00869519 (rank : 134)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	144
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
NC score	0.475114 (rank : 79)	θ value	0.00134147 (rank : 112)
Query Neighborhood Hits	325	Target Neighborhood Hits	335	Shared Neighborhood Hits	158
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PDLI2_HUMAN
NC score	0.454727 (rank : 80)	θ value	0.0330416 (rank : 159)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	130
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

RPGF2_HUMAN
NC score	0.453204 (rank : 81)	θ value	7.84624e-12 (rank : 22)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SYP2L_HUMAN
NC score	0.452550 (rank : 82)	θ value	6.43352e-06 (rank : 75)
Query Neighborhood Hits	325	Target Neighborhood Hits	400	Shared Neighborhood Hits	141
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

AFAD_HUMAN
NC score	0.452318 (rank : 83)	θ value	4.1701e-05 (rank : 84)
Query Neighborhood Hits	325	Target Neighborhood Hits	689	Shared Neighborhood Hits	155
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PDLI2_MOUSE
NC score	0.450886 (rank : 84)	θ value	0.00102713 (rank : 108)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PAR6G_HUMAN
NC score	0.449989 (rank : 85)	θ value	3.19293e-05 (rank : 83)
Query Neighborhood Hits	325	Target Neighborhood Hits	159	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PDZK4_MOUSE
NC score	0.447491 (rank : 86)	θ value	0.000461057 (rank : 99)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PAR6B_HUMAN
NC score	0.444092 (rank : 87)	θ value	0.000121331 (rank : 92)
Query Neighborhood Hits	325	Target Neighborhood Hits	126	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_MOUSE
NC score	0.443994 (rank : 88)	θ value	9.29e-05 (rank : 88)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDZK4_HUMAN
NC score	0.442862 (rank : 89)	θ value	0.00175202 (rank : 118)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PAR6B_MOUSE
NC score	0.442514 (rank : 90)	θ value	0.000121331 (rank : 93)
Query Neighborhood Hits	325	Target Neighborhood Hits	128	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

DLG5_HUMAN
NC score	0.433291 (rank : 91)	θ value	2.21117e-06 (rank : 68)
Query Neighborhood Hits	325	Target Neighborhood Hits	1088	Shared Neighborhood Hits	191
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GRASP_MOUSE
NC score	0.432066 (rank : 92)	θ value	0.0193708 (rank : 152)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_HUMAN
NC score	0.430091 (rank : 93)	θ value	0.0736092 (rank : 164)
Query Neighborhood Hits	325	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PAR6A_MOUSE
NC score	0.422488 (rank : 94)	θ value	0.00134147 (rank : 114)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6A_HUMAN
NC score	0.420916 (rank : 95)	θ value	0.00134147 (rank : 113)
Query Neighborhood Hits	325	Target Neighborhood Hits	119	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

SDCB1_MOUSE
NC score	0.420664 (rank : 96)	θ value	0.0193708 (rank : 156)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	135
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

PTN13_HUMAN
NC score	0.420058 (rank : 97)	θ value	1.06045e-08 (rank : 47)
Query Neighborhood Hits	325	Target Neighborhood Hits	471	Shared Neighborhood Hits	190
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SDCB1_HUMAN
NC score	0.419889 (rank : 98)	θ value	0.00869519 (rank : 140)
Query Neighborhood Hits	325	Target Neighborhood Hits	150	Shared Neighborhood Hits	143
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

APBA1_HUMAN
NC score	0.418170 (rank : 99)	θ value	0.00665767 (rank : 130)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PTN13_MOUSE
NC score	0.414598 (rank : 100)	θ value	1.25267e-09 (rank : 38)
Query Neighborhood Hits	325	Target Neighborhood Hits	426	Shared Neighborhood Hits	191
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

APBA2_MOUSE
NC score	0.413198 (rank : 101)	θ value	0.00102713 (rank : 105)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	153
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

RHPN1_MOUSE
NC score	0.412831 (rank : 102)	θ value	0.00035302 (rank : 97)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	135
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

APBA2_HUMAN
NC score	0.412577 (rank : 103)	θ value	0.00102713 (rank : 104)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	154
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.399982 (rank : 104)	θ value	0.00509761 (rank : 127)
Query Neighborhood Hits	325	Target Neighborhood Hits	201	Shared Neighborhood Hits	137
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

RHPN1_HUMAN
NC score	0.399502 (rank : 105)	θ value	1.43324e-05 (rank : 78)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

MPP4_HUMAN
NC score	0.399498 (rank : 106)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	325	Target Neighborhood Hits	205	Shared Neighborhood Hits	135
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PICK1_HUMAN
NC score	0.398710 (rank : 107)	θ value	0.0148317 (rank : 150)
Query Neighborhood Hits	325	Target Neighborhood Hits	132	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PSCBP_MOUSE
NC score	0.398043 (rank : 108)	θ value	0.163984 (rank : 177)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

MPP5_HUMAN
NC score	0.396939 (rank : 109)	θ value	0.00869519 (rank : 137)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	133
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.395938 (rank : 110)	θ value	0.00869519 (rank : 138)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

APBA3_MOUSE
NC score	0.392655 (rank : 111)	θ value	0.00228821 (rank : 120)
Query Neighborhood Hits	325	Target Neighborhood Hits	174	Shared Neighborhood Hits	135
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SYNP2_MOUSE
NC score	0.390637 (rank : 112)	θ value	0.00102713 (rank : 110)
Query Neighborhood Hits	325	Target Neighborhood Hits	252	Shared Neighborhood Hits	133
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

PICK1_MOUSE
NC score	0.386971 (rank : 113)	θ value	0.21417 (rank : 183)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	123
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

NEB1_HUMAN
NC score	0.382644 (rank : 114)	θ value	0.00175202 (rank : 117)
Query Neighborhood Hits	325	Target Neighborhood Hits	829	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

MPP3_MOUSE
NC score	0.381425 (rank : 115)	θ value	0.0330416 (rank : 158)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.378927 (rank : 116)	θ value	0.0330416 (rank : 157)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	126
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

DVL3_HUMAN
NC score	0.375754 (rank : 117)	θ value	0.0736092 (rank : 162)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	121
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_HUMAN
NC score	0.375480 (rank : 118)	θ value	0.0961366 (rank : 166)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	121
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL3_MOUSE
NC score	0.373509 (rank : 119)	θ value	0.0736092 (rank : 163)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

ARHGB_HUMAN
NC score	0.372791 (rank : 120)	θ value	2.44474e-05 (rank : 80)
Query Neighborhood Hits	325	Target Neighborhood Hits	375	Shared Neighborhood Hits	175
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

DVL2_MOUSE
NC score	0.370320 (rank : 121)	θ value	0.00298849 (rank : 122)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	125
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.369317 (rank : 122)	θ value	0.0148317 (rank : 147)
Query Neighborhood Hits	325	Target Neighborhood Hits	223	Shared Neighborhood Hits	129
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL1_MOUSE
NC score	0.366592 (rank : 123)	θ value	0.0961366 (rank : 167)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SYP2L_MOUSE
NC score	0.363207 (rank : 124)	θ value	5.44631e-05 (rank : 86)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

APXL_HUMAN
NC score	0.362199 (rank : 125)	θ value	0.00102713 (rank : 106)
Query Neighborhood Hits	325	Target Neighborhood Hits	553	Shared Neighborhood Hits	118
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DVL1L_HUMAN
NC score	0.359144 (rank : 126)	θ value	0.125558 (rank : 170)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	116
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

PDLI3_HUMAN
NC score	0.357829 (rank : 127)	θ value	0.00509761 (rank : 128)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SDCB2_MOUSE
NC score	0.355765 (rank : 128)	θ value	0.62314 (rank : 199)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SHAN2_HUMAN
NC score	0.353913 (rank : 129)	θ value	0.00134147 (rank : 116)
Query Neighborhood Hits	325	Target Neighborhood Hits	346	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

NEB2_HUMAN
NC score	0.353826 (rank : 130)	θ value	0.0113563 (rank : 142)
Query Neighborhood Hits	325	Target Neighborhood Hits	883	Shared Neighborhood Hits	128
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.349593 (rank : 131)	θ value	0.0113563 (rank : 143)
Query Neighborhood Hits	325	Target Neighborhood Hits	889	Shared Neighborhood Hits	130
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

MPP4_MOUSE
NC score	0.348236 (rank : 132)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	325	Target Neighborhood Hits	188	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PSCBP_HUMAN
NC score	0.346320 (rank : 133)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	325	Target Neighborhood Hits	123	Shared Neighborhood Hits	115
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PDLI1_MOUSE
NC score	0.344794 (rank : 134)	θ value	0.0113563 (rank : 144)
Query Neighborhood Hits	325	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_HUMAN
NC score	0.343413 (rank : 135)	θ value	0.00390308 (rank : 126)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_MOUSE
NC score	0.342747 (rank : 136)	θ value	0.0193708 (rank : 155)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	112
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_MOUSE
NC score	0.340822 (rank : 137)	θ value	0.00869519 (rank : 139)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

ARHGC_HUMAN
NC score	0.340572 (rank : 138)	θ value	0.000602161 (rank : 100)
Query Neighborhood Hits	325	Target Neighborhood Hits	351	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SYNP2_HUMAN
NC score	0.339155 (rank : 139)	θ value	0.00298849 (rank : 125)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI4_HUMAN
NC score	0.338436 (rank : 140)	θ value	0.0193708 (rank : 154)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	113
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

STXB4_HUMAN
NC score	0.337145 (rank : 141)	θ value	0.00665767 (rank : 132)
Query Neighborhood Hits	325	Target Neighborhood Hits	616	Shared Neighborhood Hits	105
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

ARHGC_MOUSE
NC score	0.335415 (rank : 142)	θ value	0.00134147 (rank : 111)
Query Neighborhood Hits	325	Target Neighborhood Hits	344	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SDCB2_HUMAN
NC score	0.334013 (rank : 143)	θ value	1.06291 (rank : 215)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RGS12_HUMAN
NC score	0.331961 (rank : 144)	θ value	7.1131e-05 (rank : 87)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	147
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

STXB4_MOUSE
NC score	0.330840 (rank : 145)	θ value	0.0431538 (rank : 161)
Query Neighborhood Hits	325	Target Neighborhood Hits	629	Shared Neighborhood Hits	101
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

EM55_HUMAN
NC score	0.328876 (rank : 146)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	325	Target Neighborhood Hits	228	Shared Neighborhood Hits	119
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.327977 (rank : 147)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	325	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

SHAN2_MOUSE
NC score	0.321981 (rank : 148)	θ value	0.00228821 (rank : 121)
Query Neighborhood Hits	325	Target Neighborhood Hits	446	Shared Neighborhood Hits	135
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NOS1_HUMAN
NC score	0.299943 (rank : 149)	θ value	0.0431538 (rank : 160)
Query Neighborhood Hits	325	Target Neighborhood Hits	218	Shared Neighborhood Hits	138
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LDB3_HUMAN
NC score	0.274557 (rank : 150)	θ value	0.00869519 (rank : 135)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	131
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
NC score	0.274261 (rank : 151)	θ value	0.00869519 (rank : 136)
Query Neighborhood Hits	325	Target Neighborhood Hits	510	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI5_MOUSE
NC score	0.270889 (rank : 152)	θ value	0.00134147 (rank : 115)
Query Neighborhood Hits	325	Target Neighborhood Hits	287	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_HUMAN
NC score	0.270640 (rank : 153)	θ value	0.00509761 (rank : 129)
Query Neighborhood Hits	325	Target Neighborhood Hits	322	Shared Neighborhood Hits	122
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

RIMS1_HUMAN
NC score	0.270579 (rank : 154)	θ value	4.1701e-05 (rank : 85)
Query Neighborhood Hits	325	Target Neighborhood Hits	437	Shared Neighborhood Hits	134
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PDLI7_HUMAN
NC score	0.269172 (rank : 155)	θ value	0.000786445 (rank : 103)
Query Neighborhood Hits	325	Target Neighborhood Hits	547	Shared Neighborhood Hits	144
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

MPP2_MOUSE
NC score	0.268132 (rank : 156)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_MOUSE
NC score	0.264626 (rank : 157)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	325	Target Neighborhood Hits	187	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

LRRC7_HUMAN
NC score	0.264150 (rank : 158)	θ value	0.000121331 (rank : 90)
Query Neighborhood Hits	325	Target Neighborhood Hits	423	Shared Neighborhood Hits	122
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP2_HUMAN
NC score	0.264092 (rank : 159)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	325	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

PDLI7_MOUSE
NC score	0.263472 (rank : 160)	θ value	0.000158464 (rank : 95)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	106
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LRRC7_MOUSE
NC score	0.262645 (rank : 161)	θ value	0.000121331 (rank : 91)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	118
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP6_HUMAN
NC score	0.260230 (rank : 162)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

NOS1_MOUSE
NC score	0.256247 (rank : 163)	θ value	0.0961366 (rank : 168)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LAP2_HUMAN
NC score	0.250803 (rank : 164)	θ value	0.000786445 (rank : 102)
Query Neighborhood Hits	325	Target Neighborhood Hits	499	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
NC score	0.240491 (rank : 165)	θ value	0.00102713 (rank : 107)
Query Neighborhood Hits	325	Target Neighborhood Hits	482	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SHAN1_HUMAN
NC score	0.234940 (rank : 166)	θ value	9.29e-05 (rank : 89)
Query Neighborhood Hits	325	Target Neighborhood Hits	1041	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

GIPC1_MOUSE
NC score	0.231119 (rank : 167)	θ value	0.125558 (rank : 171)
Query Neighborhood Hits	325	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

GIPC1_HUMAN
NC score	0.218542 (rank : 168)	θ value	0.163984 (rank : 175)
Query Neighborhood Hits	325	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

RIMS2_HUMAN
NC score	0.216274 (rank : 169)	θ value	0.0113563 (rank : 145)
Query Neighborhood Hits	325	Target Neighborhood Hits	342	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.214324 (rank : 170)	θ value	0.0113563 (rank : 146)
Query Neighborhood Hits	325	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

KGUA_MOUSE
NC score	0.199649 (rank : 171)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	325	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.197561 (rank : 172)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	325	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

PCLO_MOUSE
NC score	0.195844 (rank : 173)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	325	Target Neighborhood Hits	2275	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GIPC2_HUMAN
NC score	0.183086 (rank : 174)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PTN4_HUMAN
NC score	0.179858 (rank : 175)	θ value	0.00175202 (rank : 119)
Query Neighborhood Hits	325	Target Neighborhood Hits	303	Shared Neighborhood Hits	122
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.177841 (rank : 176)	θ value	0.00102713 (rank : 109)
Query Neighborhood Hits	325	Target Neighborhood Hits	258	Shared Neighborhood Hits	115
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

LMO7_HUMAN
NC score	0.174465 (rank : 177)	θ value	0.000602161 (rank : 101)
Query Neighborhood Hits	325	Target Neighborhood Hits	507	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PDZD8_HUMAN
NC score	0.140675 (rank : 178)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	325	Target Neighborhood Hits	185	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

HTRA3_MOUSE
NC score	0.133419 (rank : 179)	θ value	0.47712 (rank : 195)
Query Neighborhood Hits	325	Target Neighborhood Hits	156	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

TIAM1_HUMAN
NC score	0.132971 (rank : 180)	θ value	0.0148317 (rank : 151)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

GIPC3_HUMAN
NC score	0.132172 (rank : 181)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	325	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC2_MOUSE
NC score	0.131929 (rank : 182)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	325	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GIPC3_MOUSE
NC score	0.130824 (rank : 183)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	325	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

PDZD6_HUMAN
NC score	0.127050 (rank : 184)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	325	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

HTRA3_HUMAN
NC score	0.124564 (rank : 185)	θ value	0.62314 (rank : 198)
Query Neighborhood Hits	325	Target Neighborhood Hits	152	Shared Neighborhood Hits	64
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

RHPN2_MOUSE
NC score	0.115937 (rank : 186)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	325	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

TIAM1_MOUSE
NC score	0.105322 (rank : 187)	θ value	0.00665767 (rank : 133)
Query Neighborhood Hits	325	Target Neighborhood Hits	205	Shared Neighborhood Hits	48
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

CSKP_HUMAN
NC score	0.104675 (rank : 188)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	325	Target Neighborhood Hits	1022	Shared Neighborhood Hits	119
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

RGS3_MOUSE
NC score	0.102120 (rank : 189)	θ value	0.163984 (rank : 178)
Query Neighborhood Hits	325	Target Neighborhood Hits	1621	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CSKP_MOUSE
NC score	0.102004 (rank : 190)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	325	Target Neighborhood Hits	1027	Shared Neighborhood Hits	119
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PSMD9_HUMAN
NC score	0.101936 (rank : 191)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	325	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

RGS3_HUMAN
NC score	0.099092 (rank : 192)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	325	Target Neighborhood Hits	1375	Shared Neighborhood Hits	137
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

HTRA1_HUMAN
NC score	0.096568 (rank : 193)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

CNKR2_MOUSE
NC score	0.094865 (rank : 194)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.094831 (rank : 195)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CAR11_HUMAN
NC score	0.094627 (rank : 196)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	325	Target Neighborhood Hits	690	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

HTRA1_MOUSE
NC score	0.094110 (rank : 197)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	325	Target Neighborhood Hits	140	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

PRAX_MOUSE
NC score	0.087992 (rank : 198)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

HTRA4_HUMAN
NC score	0.085575 (rank : 199)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	325	Target Neighborhood Hits	119	Shared Neighborhood Hits	44
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

SRRM2_MOUSE
NC score	0.082097 (rank : 200)	θ value	0.00665767 (rank : 131)
Query Neighborhood Hits	325	Target Neighborhood Hits	1470	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SI1L2_HUMAN
NC score	0.076326 (rank : 201)	θ value	5.27518 (rank : 273)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

RNF41_MOUSE
NC score	0.075610 (rank : 202)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	325	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.075447 (rank : 203)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

MAST4_HUMAN
NC score	0.074782 (rank : 204)	θ value	0.0113563 (rank : 141)
Query Neighborhood Hits	325	Target Neighborhood Hits	1804	Shared Neighborhood Hits	179
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SI1L2_MOUSE
NC score	0.074623 (rank : 205)	θ value	5.27518 (rank : 274)
Query Neighborhood Hits	325	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TCOF_MOUSE
NC score	0.073911 (rank : 206)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	325	Target Neighborhood Hits	471	Shared Neighborhood Hits	42
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PSMD9_MOUSE
NC score	0.071564 (rank : 207)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	325	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

MUC1_HUMAN
NC score	0.071114 (rank : 208)	θ value	1.87187e-05 (rank : 79)
Query Neighborhood Hits	325	Target Neighborhood Hits	975	Shared Neighborhood Hits	90
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SI1L1_HUMAN
NC score	0.070884 (rank : 209)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

MAST3_HUMAN
NC score	0.068450 (rank : 210)	θ value	0.00298849 (rank : 124)
Query Neighborhood Hits	325	Target Neighborhood Hits	1128	Shared Neighborhood Hits	136
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

GSCR1_HUMAN
NC score	0.068360 (rank : 211)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	325	Target Neighborhood Hits	674	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SI1L1_MOUSE
NC score	0.068309 (rank : 212)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

EAF1_MOUSE
NC score	0.068043 (rank : 213)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	325	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

PREX1_HUMAN
NC score	0.067683 (rank : 214)	θ value	0.163984 (rank : 176)
Query Neighborhood Hits	325	Target Neighborhood Hits	177	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRRT3_HUMAN
NC score	0.067221 (rank : 215)	θ value	0.0961366 (rank : 169)
Query Neighborhood Hits	325	Target Neighborhood Hits	998	Shared Neighborhood Hits	82
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MAST2_HUMAN
NC score	0.067173 (rank : 216)	θ value	0.125558 (rank : 172)
Query Neighborhood Hits	325	Target Neighborhood Hits	1189	Shared Neighborhood Hits	135
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SIPA1_HUMAN
NC score	0.066728 (rank : 217)	θ value	0.163984 (rank : 179)
Query Neighborhood Hits	325	Target Neighborhood Hits	250	Shared Neighborhood Hits	39
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

MAST1_MOUSE
NC score	0.066451 (rank : 218)	θ value	0.21417 (rank : 182)
Query Neighborhood Hits	325	Target Neighborhood Hits	1123	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

EAF1_HUMAN
NC score	0.066387 (rank : 219)	θ value	1.81305 (rank : 226)
Query Neighborhood Hits	325	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

MAST1_HUMAN
NC score	0.066369 (rank : 220)	θ value	0.0736092 (rank : 165)
Query Neighborhood Hits	325	Target Neighborhood Hits	1146	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MY18A_MOUSE
NC score	0.066306 (rank : 221)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	325	Target Neighborhood Hits	1989	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CAR14_HUMAN
NC score	0.065613 (rank : 222)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	325	Target Neighborhood Hits	449	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

TCOF_HUMAN
NC score	0.065477 (rank : 223)	θ value	0.125558 (rank : 173)
Query Neighborhood Hits	325	Target Neighborhood Hits	543	Shared Neighborhood Hits	44
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SRRM2_HUMAN
NC score	0.065339 (rank : 224)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	325	Target Neighborhood Hits	1296	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PRAX_HUMAN
NC score	0.065205 (rank : 225)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	325	Target Neighborhood Hits	215	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

MAST2_MOUSE
NC score	0.065100 (rank : 226)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	325	Target Neighborhood Hits	1110	Shared Neighborhood Hits	131
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MUC7_HUMAN
NC score	0.064937 (rank : 227)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	325	Target Neighborhood Hits	538	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

BAT2_HUMAN
NC score	0.064497 (rank : 228)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	325	Target Neighborhood Hits	931	Shared Neighborhood Hits	85
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RHPN2_HUMAN
NC score	0.064367 (rank : 229)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	325	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

LRRC1_MOUSE
NC score	0.061864 (rank : 230)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	325	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

LRRC1_HUMAN
NC score	0.061531 (rank : 231)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	325	Target Neighborhood Hits	282	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

MY18A_HUMAN
NC score	0.060015 (rank : 232)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	325	Target Neighborhood Hits	1929	Shared Neighborhood Hits	149
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PRR12_HUMAN
NC score	0.059627 (rank : 233)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	325	Target Neighborhood Hits	460	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CAR14_MOUSE
NC score	0.059066 (rank : 234)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	325	Target Neighborhood Hits	526	Shared Neighborhood Hits	32
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

SI1L3_HUMAN
NC score	0.058534 (rank : 235)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	325	Target Neighborhood Hits	305	Shared Neighborhood Hits	56
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

PTN23_MOUSE
NC score	0.057837 (rank : 236)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	325	Target Neighborhood Hits	726	Shared Neighborhood Hits	60
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

BCL9_HUMAN
NC score	0.057734 (rank : 237)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	325	Target Neighborhood Hits	1008	Shared Neighborhood Hits	82
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PRB4S_HUMAN
NC score	0.056755 (rank : 238)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	325	Target Neighborhood Hits	330	Shared Neighborhood Hits	30
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

HTRA2_HUMAN
NC score	0.053595 (rank : 239)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	325	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

LPP_HUMAN
NC score	0.053356 (rank : 240)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	325	Target Neighborhood Hits	775	Shared Neighborhood Hits	77
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

NACAM_MOUSE
NC score	0.053102 (rank : 241)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	325	Target Neighborhood Hits	1866	Shared Neighborhood Hits	120
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SIPA1_MOUSE
NC score	0.052280 (rank : 242)	θ value	0.21417 (rank : 184)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SAV1_HUMAN
NC score	0.051097 (rank : 243)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	325	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.051060 (rank : 244)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	325	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

PCLO_HUMAN
NC score	0.050902 (rank : 245)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	325	Target Neighborhood Hits	2046	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SRRM1_MOUSE
NC score	0.050807 (rank : 246)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	325	Target Neighborhood Hits	966	Shared Neighborhood Hits	79
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PPRB_HUMAN
NC score	0.050567 (rank : 247)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	325	Target Neighborhood Hits	311	Shared Neighborhood Hits	35
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SYNPO_MOUSE
NC score	0.050145 (rank : 248)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

BAT2_MOUSE
NC score	0.049425 (rank : 249)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	325	Target Neighborhood Hits	947	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAG3_HUMAN
NC score	0.049289 (rank : 250)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	325	Target Neighborhood Hits	314	Shared Neighborhood Hits	39
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

WASIP_HUMAN
NC score	0.046598 (rank : 251)	θ value	6.88961 (rank : 300)
Query Neighborhood Hits	325	Target Neighborhood Hits	458	Shared Neighborhood Hits	47
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TAU_MOUSE
NC score	0.046116 (rank : 252)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	325	Target Neighborhood Hits	502	Shared Neighborhood Hits	45
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

BSN_HUMAN
NC score	0.044880 (rank : 253)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	325	Target Neighborhood Hits	1537	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PPRB_MOUSE
NC score	0.044174 (rank : 254)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	325	Target Neighborhood Hits	354	Shared Neighborhood Hits	43
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

MLL3_HUMAN
NC score	0.042451 (rank : 255)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	325	Target Neighborhood Hits	1644	Shared Neighborhood Hits	102
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SC24C_HUMAN
NC score	0.042445 (rank : 256)	θ value	1.81305 (rank : 231)
Query Neighborhood Hits	325	Target Neighborhood Hits	662	Shared Neighborhood Hits	59
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CPSF6_MOUSE
NC score	0.041774 (rank : 257)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	325	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.040740 (rank : 258)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	325	Target Neighborhood Hits	359	Shared Neighborhood Hits	36
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

LIMK1_HUMAN
NC score	0.040665 (rank : 259)	θ value	0.0148317 (rank : 148)
Query Neighborhood Hits	325	Target Neighborhood Hits	1005	Shared Neighborhood Hits	81
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

TGON2_HUMAN
NC score	0.040327 (rank : 260)	θ value	0.47712 (rank : 196)
Query Neighborhood Hits	325	Target Neighborhood Hits	1037	Shared Neighborhood Hits	67
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PRB3_HUMAN
NC score	0.040013 (rank : 261)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	325	Target Neighborhood Hits	318	Shared Neighborhood Hits	31
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

ENAH_MOUSE
NC score	0.039496 (rank : 262)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	325	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

AFF2_MOUSE
NC score	0.039004 (rank : 263)	θ value	0.21417 (rank : 180)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

LIMK1_MOUSE
NC score	0.038587 (rank : 264)	θ value	0.0148317 (rank : 149)
Query Neighborhood Hits	325	Target Neighborhood Hits	1008	Shared Neighborhood Hits	79
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

MAGD4_HUMAN
NC score	0.038505 (rank : 265)	θ value	0.00298849 (rank : 123)
Query Neighborhood Hits	325	Target Neighborhood Hits	338	Shared Neighborhood Hits	33
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

K1543_MOUSE
NC score	0.037481 (rank : 266)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	56
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MLL4_HUMAN
NC score	0.036567 (rank : 267)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	325	Target Neighborhood Hits	722	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SON_HUMAN
NC score	0.036293 (rank : 268)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	325	Target Neighborhood Hits	1568	Shared Neighborhood Hits	98
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYN1_MOUSE
NC score	0.035771 (rank : 269)	θ value	5.27518 (rank : 275)
Query Neighborhood Hits	325	Target Neighborhood Hits	363	Shared Neighborhood Hits	38
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CTDP1_HUMAN
NC score	0.035080 (rank : 270)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

SOS2_HUMAN
NC score	0.034259 (rank : 271)	θ value	4.03905 (rank : 259)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	21
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

NCOA6_MOUSE
NC score	0.033777 (rank : 272)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	325	Target Neighborhood Hits	1076	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PER3_HUMAN
NC score	0.033719 (rank : 273)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	325	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ABLM1_HUMAN
NC score	0.032754 (rank : 274)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	325	Target Neighborhood Hits	387	Shared Neighborhood Hits	24
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

RERE_HUMAN
NC score	0.031676 (rank : 275)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	325	Target Neighborhood Hits	779	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

AXN2_HUMAN
NC score	0.030960 (rank : 276)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	325	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

ENAH_HUMAN
NC score	0.030177 (rank : 277)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	325	Target Neighborhood Hits	784	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

TCGAP_HUMAN
NC score	0.029310 (rank : 278)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	325	Target Neighborhood Hits	872	Shared Neighborhood Hits	72
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CBL_MOUSE
NC score	0.028697 (rank : 279)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	325	Target Neighborhood Hits	426	Shared Neighborhood Hits	36
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TAF9_MOUSE
NC score	0.026811 (rank : 280)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	325	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

EAN57_HUMAN
NC score	0.026247 (rank : 281)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	325	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

PHLB1_HUMAN
NC score	0.026124 (rank : 282)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	325	Target Neighborhood Hits	1038	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TAB3_MOUSE
NC score	0.025774 (rank : 283)	θ value	5.27518 (rank : 276)
Query Neighborhood Hits	325	Target Neighborhood Hits	273	Shared Neighborhood Hits	38
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

BPTF_HUMAN
NC score	0.025581 (rank : 284)	θ value	0.21417 (rank : 181)
Query Neighborhood Hits	325	Target Neighborhood Hits	786	Shared Neighborhood Hits	37
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PER1_HUMAN
NC score	0.025436 (rank : 285)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	325	Target Neighborhood Hits	215	Shared Neighborhood Hits	33
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PHC2_MOUSE
NC score	0.025365 (rank : 286)	θ value	1.81305 (rank : 228)
Query Neighborhood Hits	325	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PER1_MOUSE
NC score	0.025346 (rank : 287)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	325	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

BAZ2A_HUMAN
NC score	0.024972 (rank : 288)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	325	Target Neighborhood Hits	780	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

RANB9_HUMAN
NC score	0.023547 (rank : 289)	θ value	2.36792 (rank : 237)
Query Neighborhood Hits	325	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

AKA10_MOUSE
NC score	0.023352 (rank : 290)	θ value	4.03905 (rank : 248)
Query Neighborhood Hits	325	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

BCOR_HUMAN
NC score	0.022128 (rank : 291)	θ value	0.62314 (rank : 197)
Query Neighborhood Hits	325	Target Neighborhood Hits	609	Shared Neighborhood Hits	33
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANK2_HUMAN
NC score	0.022125 (rank : 292)	θ value	2.36792 (rank : 233)
Query Neighborhood Hits	325	Target Neighborhood Hits	1615	Shared Neighborhood Hits	88
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

KI13B_HUMAN
NC score	0.020350 (rank : 293)	θ value	0.0193708 (rank : 153)
Query Neighborhood Hits	325	Target Neighborhood Hits	492	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

SOX30_MOUSE
NC score	0.019826 (rank : 294)	θ value	0.62314 (rank : 200)
Query Neighborhood Hits	325	Target Neighborhood Hits	374	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TACC3_HUMAN
NC score	0.019341 (rank : 295)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	325	Target Neighborhood Hits	779	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

BRD8_MOUSE
NC score	0.019182 (rank : 296)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	325	Target Neighborhood Hits	422	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

GATA3_HUMAN
NC score	0.019035 (rank : 297)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	325	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P23771, Q96J16	Gene names	GATA3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

PAF49_MOUSE
NC score	0.018865 (rank : 298)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	325	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

GATA3_MOUSE
NC score	0.017962 (rank : 299)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	325	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	P23772	Gene names	Gata3, Gata-3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

GIT1_HUMAN
NC score	0.017854 (rank : 300)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	325	Target Neighborhood Hits	336	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

TLE1_MOUSE
NC score	0.017779 (rank : 301)	θ value	0.62314 (rank : 201)
Query Neighborhood Hits	325	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

PO6F2_HUMAN
NC score	0.017037 (rank : 302)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	325	Target Neighborhood Hits	618	Shared Neighborhood Hits	35
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

GIT1_MOUSE
NC score	0.016989 (rank : 303)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	325	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

IF39_HUMAN
NC score	0.016492 (rank : 304)	θ value	4.03905 (rank : 254)
Query Neighborhood Hits	325	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

TATD2_HUMAN
NC score	0.015908 (rank : 305)	θ value	5.27518 (rank : 277)
Query Neighborhood Hits	325	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

CO4A5_HUMAN
NC score	0.015891 (rank : 306)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	325	Target Neighborhood Hits	383	Shared Neighborhood Hits	30
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

ASPP1_HUMAN
NC score	0.015643 (rank : 307)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	325	Target Neighborhood Hits	956	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EMID2_MOUSE
NC score	0.015310 (rank : 308)	θ value	2.36792 (rank : 234)
Query Neighborhood Hits	325	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

TLE4_MOUSE
NC score	0.015173 (rank : 309)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	325	Target Neighborhood Hits	482	Shared Neighborhood Hits	23
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.014803 (rank : 310)	θ value	1.81305 (rank : 232)
Query Neighborhood Hits	325	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

NOL11_HUMAN
NC score	0.014289 (rank : 311)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	325	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8H0, Q7L5S1, Q9UG18	Gene names	NOL11
Domain Architecture	No domain graphic available
Description	Nucleolar protein 11.

TLE3_HUMAN
NC score	0.014062 (rank : 312)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	325	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TIF1G_MOUSE
NC score	0.013650 (rank : 313)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	325	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

EP400_HUMAN
NC score	0.013565 (rank : 314)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	325	Target Neighborhood Hits	556	Shared Neighborhood Hits	39
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

NPAS4_MOUSE
NC score	0.012731 (rank : 315)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

SLIK1_MOUSE
NC score	0.012500 (rank : 316)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

FOXN4_HUMAN
NC score	0.012355 (rank : 317)	θ value	2.36792 (rank : 235)
Query Neighborhood Hits	325	Target Neighborhood Hits	248	Shared Neighborhood Hits	16
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

FBX40_MOUSE
NC score	0.011538 (rank : 318)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	325	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P62932	Gene names	Fbxo40
Domain Architecture	No domain graphic available
Description	F-box only protein 40.

LRC25_HUMAN
NC score	0.011239 (rank : 319)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	325	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N386, Q8N9A5	Gene names	LRRC25, MAPA
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 25 precursor (Monocyte and plasmacytoid-activated protein).

ELL_MOUSE
NC score	0.011116 (rank : 320)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

RUSC1_MOUSE
NC score	0.010928 (rank : 321)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	325	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

TCF19_MOUSE
NC score	0.010792 (rank : 322)	θ value	6.88961 (rank : 299)
Query Neighborhood Hits	325	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

HSF1_HUMAN
NC score	0.010511 (rank : 323)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	325	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

SL9A5_HUMAN
NC score	0.010028 (rank : 324)	θ value	2.36792 (rank : 238)
Query Neighborhood Hits	325	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q14940, Q9Y626	Gene names	SLC9A5, NHE5
Domain Architecture
Description	Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5).

SRBS1_HUMAN
NC score	0.009885 (rank : 325)	θ value	2.36792 (rank : 239)
Query Neighborhood Hits	325	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ZN687_HUMAN
NC score	0.009763 (rank : 326)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	325	Target Neighborhood Hits	1244	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CO9A2_MOUSE
NC score	0.009398 (rank : 327)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

MAGB6_HUMAN
NC score	0.009360 (rank : 328)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	325	Target Neighborhood Hits	184	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

PHAR3_MOUSE
NC score	0.009188 (rank : 329)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	325	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

TTLL5_HUMAN
NC score	0.009138 (rank : 330)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	325	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

STAU2_HUMAN
NC score	0.008618 (rank : 331)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	325	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

ATF7_HUMAN
NC score	0.008542 (rank : 332)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ICB1_MOUSE
NC score	0.008368 (rank : 333)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	325	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

PIGG_HUMAN
NC score	0.007976 (rank : 334)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	325	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

STAU2_MOUSE
NC score	0.007960 (rank : 335)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	325	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

G3BP_MOUSE
NC score	0.006018 (rank : 336)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	325	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

SPIB_MOUSE
NC score	0.005491 (rank : 337)	θ value	6.88961 (rank : 298)
Query Neighborhood Hits	325	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

PGCB_HUMAN
NC score	0.004938 (rank : 338)	θ value	1.81305 (rank : 227)
Query Neighborhood Hits	325	Target Neighborhood Hits	478	Shared Neighborhood Hits	19
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ESAM_MOUSE
NC score	0.003784 (rank : 339)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	325	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ROBO3_MOUSE
NC score	0.003694 (rank : 340)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	325	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

AP2A2_HUMAN
NC score	0.003174 (rank : 341)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	325	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

TITIN_HUMAN
NC score	0.002397 (rank : 342)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	325	Target Neighborhood Hits	2923	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RXRB_HUMAN
NC score	0.002355 (rank : 343)	θ value	6.88961 (rank : 297)
Query Neighborhood Hits	325	Target Neighborhood Hits	280	Shared Neighborhood Hits	20
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

TACC1_HUMAN
NC score	0.002182 (rank : 344)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	325	Target Neighborhood Hits	597	Shared Neighborhood Hits	16
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

SC6A5_MOUSE
NC score	0.001766 (rank : 345)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	325	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

PAX3_HUMAN
NC score	0.001172 (rank : 346)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	325	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

GIPR_HUMAN
NC score	0.001149 (rank : 347)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	325	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

ROBO2_MOUSE
NC score	0.000742 (rank : 348)	θ value	1.81305 (rank : 229)
Query Neighborhood Hits	325	Target Neighborhood Hits	504	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ZN687_MOUSE
NC score	0.000390 (rank : 349)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	325	Target Neighborhood Hits	913	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SSPO_MOUSE
NC score	-0.001984 (rank : 350)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	325	Target Neighborhood Hits	800	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ZN335_HUMAN
NC score	-0.002525 (rank : 351)	θ value	0.125558 (rank : 174)
Query Neighborhood Hits	325	Target Neighborhood Hits	973	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

LTB1L_HUMAN
NC score	-0.002672 (rank : 352)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	325	Target Neighborhood Hits	553	Shared Neighborhood Hits	15
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ZN217_HUMAN
NC score	-0.003108 (rank : 353)	θ value	0.813845 (rank : 206)
Query Neighborhood Hits	325	Target Neighborhood Hits	905	Shared Neighborhood Hits	24
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

RAB5A_HUMAN
NC score	-0.003434 (rank : 354)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	325	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	P20339	Gene names	RAB5A, RAB5
Domain Architecture
Description	Ras-related protein Rab-5A.

GLI1_HUMAN
NC score	-0.004115 (rank : 355)	θ value	2.36792 (rank : 236)
Query Neighborhood Hits	325	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

GLI2_HUMAN
NC score	-0.005061 (rank : 356)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	325	Target Neighborhood Hits	971	Shared Neighborhood Hits	31
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).