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Network neighborhood for query Sequence : STAU2_HUMAN

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STAU2_HUMAN
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STAU2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_MOUSE
θ value	0 (rank : 2)	NC score	0.998388 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU1_HUMAN
θ value	7.66637e-92 (rank : 3)	NC score	0.930971 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

STAU1_MOUSE
θ value	2.1655e-78 (rank : 4)	NC score	0.923561 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

PRKRA_MOUSE
θ value	7.58209e-15 (rank : 5)	NC score	0.595981 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).

PRKRA_HUMAN
θ value	1.68911e-14 (rank : 6)	NC score	0.592697 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	O75569, Q53G24, Q6X7T5, Q8NDK4	Gene names	PRKRA, PACT, RAX
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X).

ILF3_MOUSE
θ value	7.34386e-10 (rank : 7)	NC score	0.436981 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

RED1_MOUSE
θ value	2.79066e-09 (rank : 8)	NC score	0.430855 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED1_HUMAN
θ value	3.64472e-09 (rank : 9)	NC score	0.430691 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

TRBP2_HUMAN
θ value	1.80886e-08 (rank : 10)	NC score	0.514409 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

DSRAD_MOUSE
θ value	1.53129e-07 (rank : 11)	NC score	0.375865 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

ILF3_HUMAN
θ value	1.99992e-07 (rank : 12)	NC score	0.421163 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

TRBP2_MOUSE
θ value	7.59969e-07 (rank : 13)	NC score	0.498609 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

RED2_MOUSE
θ value	2.21117e-06 (rank : 14)	NC score	0.381134 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI20, Q3UTP1, Q8CC51, Q9JIE5	Gene names	Adarb2, Adar3, Red2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

DSRAD_HUMAN
θ value	0.000158464 (rank : 15)	NC score	0.380507 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

RED2_HUMAN
θ value	0.000602161 (rank : 16)	NC score	0.370259 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

E2AK2_HUMAN
θ value	0.0431538 (rank : 17)	NC score	0.036360 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	856	Shared Neighborhood Hits	16
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

E2AK2_MOUSE
θ value	0.0431538 (rank : 18)	NC score	0.028622 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

RNC_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.082844 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	176	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

BAT2_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.024481 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	947	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

UB7I1_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.034854 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

HRX_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.020527 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	825	Shared Neighborhood Hits	7
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AFF2_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.020172 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

SON_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.029172 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	1568	Shared Neighborhood Hits	19
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.042781 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	957	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

UBP42_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.008601 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

CEND3_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.010900 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEP35_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.009970 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	811	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CO039_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.022575 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

PRR12_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.018534 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	460	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

DEPD5_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.018356 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75140, Q5K3V5, Q5THY9, Q5THZ0, Q5THZ1, Q5THZ3, Q68DR1, Q6MZX3, Q6PEZ1, Q9UGV8, Q9UH13	Gene names	DEPDC5, KIAA0645
Domain Architecture
Description	DEP domain-containing protein 5.

MPP8_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.006023 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	948	Shared Neighborhood Hits	8
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

WHRN_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.008618 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	325	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

ZN533_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.014265 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q569K4, Q49A04, Q6ZMZ7, Q8IY01, Q8N8H2, Q96DK4	Gene names	ZNF533
Domain Architecture	No domain graphic available
Description	Zinc finger protein 533.

ILF2_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.057420 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.057420 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

Hits sorted by NC score

STAU2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_MOUSE
NC score	0.998388 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU1_HUMAN
NC score	0.930971 (rank : 3)	θ value	7.66637e-92 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

STAU1_MOUSE
NC score	0.923561 (rank : 4)	θ value	2.1655e-78 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

PRKRA_MOUSE
NC score	0.595981 (rank : 5)	θ value	7.58209e-15 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).

PRKRA_HUMAN
NC score	0.592697 (rank : 6)	θ value	1.68911e-14 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	O75569, Q53G24, Q6X7T5, Q8NDK4	Gene names	PRKRA, PACT, RAX
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X).

TRBP2_HUMAN
NC score	0.514409 (rank : 7)	θ value	1.80886e-08 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

TRBP2_MOUSE
NC score	0.498609 (rank : 8)	θ value	7.59969e-07 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

ILF3_MOUSE
NC score	0.436981 (rank : 9)	θ value	7.34386e-10 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

RED1_MOUSE
NC score	0.430855 (rank : 10)	θ value	2.79066e-09 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED1_HUMAN
NC score	0.430691 (rank : 11)	θ value	3.64472e-09 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

ILF3_HUMAN
NC score	0.421163 (rank : 12)	θ value	1.99992e-07 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

RED2_MOUSE
NC score	0.381134 (rank : 13)	θ value	2.21117e-06 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI20, Q3UTP1, Q8CC51, Q9JIE5	Gene names	Adarb2, Adar3, Red2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

DSRAD_HUMAN
NC score	0.380507 (rank : 14)	θ value	0.000158464 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

DSRAD_MOUSE
NC score	0.375865 (rank : 15)	θ value	1.53129e-07 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

RED2_HUMAN
NC score	0.370259 (rank : 16)	θ value	0.000602161 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RNC_HUMAN
NC score	0.082844 (rank : 17)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	176	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

ILF2_HUMAN
NC score	0.057420 (rank : 18)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
NC score	0.057420 (rank : 19)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

SON_MOUSE
NC score	0.042781 (rank : 20)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	957	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

E2AK2_HUMAN
NC score	0.036360 (rank : 21)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	856	Shared Neighborhood Hits	16
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

UB7I1_MOUSE
NC score	0.034854 (rank : 22)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

SON_HUMAN
NC score	0.029172 (rank : 23)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	1568	Shared Neighborhood Hits	19
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

E2AK2_MOUSE
NC score	0.028622 (rank : 24)	θ value	0.0431538 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

BAT2_MOUSE
NC score	0.024481 (rank : 25)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	947	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO039_HUMAN
NC score	0.022575 (rank : 26)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

HRX_HUMAN
NC score	0.020527 (rank : 27)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	825	Shared Neighborhood Hits	7
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AFF2_MOUSE
NC score	0.020172 (rank : 28)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

PRR12_HUMAN
NC score	0.018534 (rank : 29)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	460	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

DEPD5_HUMAN
NC score	0.018356 (rank : 30)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75140, Q5K3V5, Q5THY9, Q5THZ0, Q5THZ1, Q5THZ3, Q68DR1, Q6MZX3, Q6PEZ1, Q9UGV8, Q9UH13	Gene names	DEPDC5, KIAA0645
Domain Architecture
Description	DEP domain-containing protein 5.

ZN533_HUMAN
NC score	0.014265 (rank : 31)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q569K4, Q49A04, Q6ZMZ7, Q8IY01, Q8N8H2, Q96DK4	Gene names	ZNF533
Domain Architecture	No domain graphic available
Description	Zinc finger protein 533.

CEND3_MOUSE
NC score	0.010900 (rank : 32)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEP35_HUMAN
NC score	0.009970 (rank : 33)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	811	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

WHRN_HUMAN
NC score	0.008618 (rank : 34)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	325	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

UBP42_HUMAN
NC score	0.008601 (rank : 35)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

MPP8_HUMAN
NC score	0.006023 (rank : 36)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	948	Shared Neighborhood Hits	8
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.