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Network neighborhood for query Sequence : SI1L2_HUMAN

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SI1L2_HUMAN
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SI1L1_HUMAN
θ value	0 (rank : 1)	NC score	0.977285 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0 (rank : 2)	NC score	0.974679 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	0 (rank : 4)	NC score	0.996277 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	100
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
θ value	0 (rank : 5)	NC score	0.956940 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	305	Shared Neighborhood Hits	54
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_HUMAN
θ value	1.11673e-175 (rank : 6)	NC score	0.931699 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
θ value	2.84643e-171 (rank : 7)	NC score	0.941434 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	158	Shared Neighborhood Hits	42
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

RGP2_HUMAN
θ value	1.61343e-57 (rank : 8)	NC score	0.884649 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
θ value	3.18553e-13 (rank : 9)	NC score	0.463539 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
θ value	2.69671e-12 (rank : 10)	NC score	0.450216 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
θ value	6.64225e-11 (rank : 11)	NC score	0.436685 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	59	Shared Neighborhood Hits	13
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
θ value	3.64472e-09 (rank : 12)	NC score	0.415448 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN1_HUMAN
θ value	0.000121331 (rank : 13)	NC score	0.103695 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	1041	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

COHA1_HUMAN
θ value	0.000602161 (rank : 14)	NC score	0.031293 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	400	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

NHERF_HUMAN
θ value	0.00869519 (rank : 15)	NC score	0.134021 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
θ value	0.0148317 (rank : 16)	NC score	0.127672 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	195	Shared Neighborhood Hits	45
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA2_HUMAN
θ value	0.0252991 (rank : 17)	NC score	0.143444 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	45
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.0252991 (rank : 18)	NC score	0.143114 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

ARHGB_HUMAN
θ value	0.0330416 (rank : 19)	NC score	0.085182 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	375	Shared Neighborhood Hits	51
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LAP4_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.051828 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	608	Shared Neighborhood Hits	48
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

APBA1_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.128323 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	325	Shared Neighborhood Hits	48
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

GOGA3_MOUSE
θ value	0.0431538 (rank : 22)	NC score	0.041545 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	1437	Shared Neighborhood Hits	54
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SHAN2_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.148023 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0431538 (rank : 24)	NC score	0.134808 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	446	Shared Neighborhood Hits	43
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

LAP4_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.056931 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	590	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

APBA3_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.127390 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.140718 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	43
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

USH1C_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.109220 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	327	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.163984 (rank : 29)	NC score	0.106580 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	557	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ARHGC_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.065127 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GOGA4_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.036668 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	2034	Shared Neighborhood Hits	59
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

K1967_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.038641 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

MYOC_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.058463 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	489	Shared Neighborhood Hits	42
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

NHRF2_HUMAN
θ value	0.21417 (rank : 34)	NC score	0.104752 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PDZD3_MOUSE
θ value	0.21417 (rank : 35)	NC score	0.112708 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	171	Shared Neighborhood Hits	43
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

MYH14_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.033703 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	995	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ARHGC_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.059812 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

DYHC_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.037458 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	733	Shared Neighborhood Hits	40
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.037336 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	729	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

LMNB2_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.025859 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	674	Shared Neighborhood Hits	46
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LYN_HUMAN
θ value	0.47712 (rank : 41)	NC score	0.002266 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	1022	Shared Neighborhood Hits	6
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MYH9_MOUSE
θ value	0.47712 (rank : 42)	NC score	0.034430 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	1829	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GOGA3_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.036975 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	1317	Shared Neighborhood Hits	54
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

NHRF2_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.097343 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	194	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

CP250_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.032652 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	1805	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

LAMA5_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.012164 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EEA1_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.030370 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	1796	Shared Neighborhood Hits	54
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

NUMA1_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.033293 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	1523	Shared Neighborhood Hits	57
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PTN13_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.037021 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	471	Shared Neighborhood Hits	44
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SM1L2_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.025547 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	918	Shared Neighborhood Hits	42
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

CT152_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.024406 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

MYH14_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.033086 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	1225	Shared Neighborhood Hits	51
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH9_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.033872 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	1762	Shared Neighborhood Hits	57
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RPGF6_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.047294 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	266	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

K1219_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.037720 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KIF17_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.016904 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	452	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LMNB2_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.023551 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	723	Shared Neighborhood Hits	46
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

MAGI1_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.063099 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	388	Shared Neighborhood Hits	50
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.059815 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	403	Shared Neighborhood Hits	45
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MYH10_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.032099 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	1620	Shared Neighborhood Hits	55
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.032347 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	1777	Shared Neighborhood Hits	55
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

REST_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.026994 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	1506	Shared Neighborhood Hits	49
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RUFY2_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.038614 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	1208	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.045319 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	820	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

AFF1_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.013617 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	9
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

GCC2_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.035268 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	1558	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MYH10_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.031720 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	1612	Shared Neighborhood Hits	55
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PDZD1_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.089177 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

RBP24_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.034826 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	1559	Shared Neighborhood Hits	54
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RUFY1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.045106 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	848	Shared Neighborhood Hits	49
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SIP1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.001977 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	832	Shared Neighborhood Hits	10
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.001916 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	870	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

VAPB_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.034833 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

CCHCR_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.032373 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	717	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

FCRL5_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.010371 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

LYN_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.000654 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	1023	Shared Neighborhood Hits	6
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MPDZ_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.058480 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	261	Shared Neighborhood Hits	46
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PARD3_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.073848 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	312	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.081755 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	290	Shared Neighborhood Hits	45
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SPTN5_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.017412 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

XBP1_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.024737 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

ZMYM3_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.015528 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	223	Shared Neighborhood Hits	11
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

DMBT1_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.003574 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

KIF3A_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.017033 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	715	Shared Neighborhood Hits	48
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MPDZ_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.056702 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	298	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PDZ11_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.065521 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	160	Shared Neighborhood Hits	37
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.063300 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RN103_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.019883 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

SPAG5_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.026768 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	612	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

ZN318_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.018196 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	642	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AZI1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.027215 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	1000	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BASI_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.007192 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

CT152_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.019960 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

EP15R_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.029477 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

FYV1_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.012252 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

GRIP2_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.047643 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	256	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

INADL_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.046839 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	290	Shared Neighborhood Hits	41
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

KIF3A_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.013476 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	704	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYH11_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.030913 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	1806	Shared Neighborhood Hits	59
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NAF1_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.035429 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	937	Shared Neighborhood Hits	50
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

PDZD3_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.080259 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PEPL_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.033039 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	1105	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SDCB1_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.048734 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

TPR_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.034390 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	1921	Shared Neighborhood Hits	63
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

WHRN_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.076326 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	325	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.074292 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ZCPW1_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.013251 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

ZNF91_HUMAN
θ value	5.27518 (rank : 108)	NC score	-0.001822 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	797	Shared Neighborhood Hits	7
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

CAF1A_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.021577 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	750	Shared Neighborhood Hits	42
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCDC6_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.046990 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	723	Shared Neighborhood Hits	47
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CP250_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.029061 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	1583	Shared Neighborhood Hits	57
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DMPK_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.001675 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	944	Shared Neighborhood Hits	21
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

IQEC2_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.019792 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	403	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.018914 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	24
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

K1219_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.032610 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

PB1_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.006088 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PDZD1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.072330 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	191	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PEX14_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.011854 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

RGS3_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.011237 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	1621	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SPEG_MOUSE
θ value	6.88961 (rank : 120)	NC score	-0.001000 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	1959	Shared Neighborhood Hits	18
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

COHA1_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.014382 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CP135_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.024391 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	1278	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GTF2I_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.006496 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

JIP4_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.020529 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	585	Shared Neighborhood Hits	41
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

K0256_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.008666 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

KCTD8_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.007784 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZWB6	Gene names	KCTD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

RUFY1_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.041674 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	765	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

TSP2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.000811 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	359	Shared Neighborhood Hits	3
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZN228_HUMAN
θ value	8.99809 (rank : 129)	NC score	-0.002081 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	775	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJU3, Q9HCA7	Gene names	ZNF228
Domain Architecture
Description	Zinc finger protein 228.

ZN559_HUMAN
θ value	8.99809 (rank : 130)	NC score	-0.002052 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	746	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BR84	Gene names	ZNF559
Domain Architecture	No domain graphic available
Description	Zinc finger protein 559.

ZNF14_HUMAN
θ value	8.99809 (rank : 131)	NC score	-0.002021 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	760	Shared Neighborhood Hits	10
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

PDZD7_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.055942 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SDCB2_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.053775 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

Hits sorted by NC score

SI1L2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
NC score	0.996277 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	100
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L1_HUMAN
NC score	0.977285 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
NC score	0.974679 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L3_HUMAN
NC score	0.956940 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	305	Shared Neighborhood Hits	54
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_MOUSE
NC score	0.941434 (rank : 6)	θ value	2.84643e-171 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	158	Shared Neighborhood Hits	42
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SIPA1_HUMAN
NC score	0.931699 (rank : 7)	θ value	1.11673e-175 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

RGP2_HUMAN
NC score	0.884649 (rank : 8)	θ value	1.61343e-57 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
NC score	0.463539 (rank : 9)	θ value	3.18553e-13 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
NC score	0.450216 (rank : 10)	θ value	2.69671e-12 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
NC score	0.436685 (rank : 11)	θ value	6.64225e-11 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	59	Shared Neighborhood Hits	13
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
NC score	0.415448 (rank : 12)	θ value	3.64472e-09 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN2_HUMAN
NC score	0.148023 (rank : 13)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

APBA2_HUMAN
NC score	0.143444 (rank : 14)	θ value	0.0252991 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	45
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
NC score	0.143114 (rank : 15)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_MOUSE
NC score	0.140718 (rank : 16)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	43
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN2_MOUSE
NC score	0.134808 (rank : 17)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	446	Shared Neighborhood Hits	43
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NHERF_HUMAN
NC score	0.134021 (rank : 18)	θ value	0.00869519 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA1_HUMAN
NC score	0.128323 (rank : 19)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	325	Shared Neighborhood Hits	48
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

NHERF_MOUSE
NC score	0.127672 (rank : 20)	θ value	0.0148317 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	195	Shared Neighborhood Hits	45
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA3_HUMAN
NC score	0.127390 (rank : 21)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PDZD3_MOUSE
NC score	0.112708 (rank : 22)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	171	Shared Neighborhood Hits	43
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

USH1C_HUMAN
NC score	0.109220 (rank : 23)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	327	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
NC score	0.106580 (rank : 24)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	557	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

NHRF2_HUMAN
NC score	0.104752 (rank : 25)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

SHAN1_HUMAN
NC score	0.103695 (rank : 26)	θ value	0.000121331 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	1041	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

NHRF2_MOUSE
NC score	0.097343 (rank : 27)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	194	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD1_HUMAN
NC score	0.089177 (rank : 28)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ARHGB_HUMAN
NC score	0.085182 (rank : 29)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	375	Shared Neighborhood Hits	51
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PARD3_MOUSE
NC score	0.081755 (rank : 30)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	290	Shared Neighborhood Hits	45
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD3_HUMAN
NC score	0.080259 (rank : 31)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

WHRN_HUMAN
NC score	0.076326 (rank : 32)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	325	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.074292 (rank : 33)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PARD3_HUMAN
NC score	0.073848 (rank : 34)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	312	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD1_MOUSE
NC score	0.072330 (rank : 35)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	191	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZ11_HUMAN
NC score	0.065521 (rank : 36)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	160	Shared Neighborhood Hits	37
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

ARHGC_MOUSE
NC score	0.065127 (rank : 37)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PDZ11_MOUSE
NC score	0.063300 (rank : 38)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MAGI1_HUMAN
NC score	0.063099 (rank : 39)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	388	Shared Neighborhood Hits	50
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.059815 (rank : 40)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	403	Shared Neighborhood Hits	45
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

ARHGC_HUMAN
NC score	0.059812 (rank : 41)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MPDZ_HUMAN
NC score	0.058480 (rank : 42)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	261	Shared Neighborhood Hits	46
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MYOC_HUMAN
NC score	0.058463 (rank : 43)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	489	Shared Neighborhood Hits	42
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

LAP4_MOUSE
NC score	0.056931 (rank : 44)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	590	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MPDZ_MOUSE
NC score	0.056702 (rank : 45)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	298	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PDZD7_HUMAN
NC score	0.055942 (rank : 46)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SDCB2_HUMAN
NC score	0.053775 (rank : 47)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

LAP4_HUMAN
NC score	0.051828 (rank : 48)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	608	Shared Neighborhood Hits	48
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

SDCB1_HUMAN
NC score	0.048734 (rank : 49)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

GRIP2_HUMAN
NC score	0.047643 (rank : 50)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	256	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

RPGF6_HUMAN
NC score	0.047294 (rank : 51)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	266	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

CCDC6_HUMAN
NC score	0.046990 (rank : 52)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	723	Shared Neighborhood Hits	47
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

INADL_MOUSE
NC score	0.046839 (rank : 53)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	290	Shared Neighborhood Hits	41
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

RUFY2_MOUSE
NC score	0.045319 (rank : 54)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	820	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY1_HUMAN
NC score	0.045106 (rank : 55)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	848	Shared Neighborhood Hits	49
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
NC score	0.041674 (rank : 56)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	765	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

GOGA3_MOUSE
NC score	0.041545 (rank : 57)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	1437	Shared Neighborhood Hits	54
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

K1967_MOUSE
NC score	0.038641 (rank : 58)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

RUFY2_HUMAN
NC score	0.038614 (rank : 59)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	1208	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

K1219_HUMAN
NC score	0.037720 (rank : 60)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

DYHC_HUMAN
NC score	0.037458 (rank : 61)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	733	Shared Neighborhood Hits	40
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.037336 (rank : 62)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	729	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

PTN13_HUMAN
NC score	0.037021 (rank : 63)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	471	Shared Neighborhood Hits	44
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

GOGA3_HUMAN
NC score	0.036975 (rank : 64)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	1317	Shared Neighborhood Hits	54
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA4_HUMAN
NC score	0.036668 (rank : 65)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	2034	Shared Neighborhood Hits	59
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

NAF1_HUMAN
NC score	0.035429 (rank : 66)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	937	Shared Neighborhood Hits	50
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

GCC2_HUMAN
NC score	0.035268 (rank : 67)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	1558	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

VAPB_HUMAN
NC score	0.034833 (rank : 68)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

RBP24_HUMAN
NC score	0.034826 (rank : 69)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	1559	Shared Neighborhood Hits	54
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

MYH9_MOUSE
NC score	0.034430 (rank : 70)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	1829	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TPR_HUMAN
NC score	0.034390 (rank : 71)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	1921	Shared Neighborhood Hits	63
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MYH9_HUMAN
NC score	0.033872 (rank : 72)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	1762	Shared Neighborhood Hits	57
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH14_HUMAN
NC score	0.033703 (rank : 73)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	995	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NUMA1_HUMAN
NC score	0.033293 (rank : 74)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	1523	Shared Neighborhood Hits	57
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

MYH14_MOUSE
NC score	0.033086 (rank : 75)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	1225	Shared Neighborhood Hits	51
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PEPL_MOUSE
NC score	0.033039 (rank : 76)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	1105	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CP250_HUMAN
NC score	0.032652 (rank : 77)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	1805	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

K1219_MOUSE
NC score	0.032610 (rank : 78)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

CCHCR_HUMAN
NC score	0.032373 (rank : 79)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	717	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

MYH11_MOUSE
NC score	0.032347 (rank : 80)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	1777	Shared Neighborhood Hits	55
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH10_HUMAN
NC score	0.032099 (rank : 81)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	1620	Shared Neighborhood Hits	55
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.031720 (rank : 82)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	1612	Shared Neighborhood Hits	55
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

COHA1_HUMAN
NC score	0.031293 (rank : 83)	θ value	0.000602161 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	400	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MYH11_HUMAN
NC score	0.030913 (rank : 84)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	1806	Shared Neighborhood Hits	59
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

EEA1_HUMAN
NC score	0.030370 (rank : 85)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	1796	Shared Neighborhood Hits	54
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EP15R_MOUSE
NC score	0.029477 (rank : 86)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

CP250_MOUSE
NC score	0.029061 (rank : 87)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	1583	Shared Neighborhood Hits	57
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

AZI1_HUMAN
NC score	0.027215 (rank : 88)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	1000	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

REST_MOUSE
NC score	0.026994 (rank : 89)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	1506	Shared Neighborhood Hits	49
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SPAG5_MOUSE
NC score	0.026768 (rank : 90)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	612	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

LMNB2_MOUSE
NC score	0.025859 (rank : 91)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	674	Shared Neighborhood Hits	46
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

SM1L2_MOUSE
NC score	0.025547 (rank : 92)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	918	Shared Neighborhood Hits	42
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

XBP1_MOUSE
NC score	0.024737 (rank : 93)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

CT152_MOUSE
NC score	0.024406 (rank : 94)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

CP135_MOUSE
NC score	0.024391 (rank : 95)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	1278	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

LMNB2_HUMAN
NC score	0.023551 (rank : 96)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	723	Shared Neighborhood Hits	46
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

CAF1A_HUMAN
NC score	0.021577 (rank : 97)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	750	Shared Neighborhood Hits	42
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

JIP4_HUMAN
NC score	0.020529 (rank : 98)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	585	Shared Neighborhood Hits	41
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

CT152_HUMAN
NC score	0.019960 (rank : 99)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

RN103_HUMAN
NC score	0.019883 (rank : 100)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

IQEC2_HUMAN
NC score	0.019792 (rank : 101)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	403	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
NC score	0.018914 (rank : 102)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	24
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

ZN318_MOUSE
NC score	0.018196 (rank : 103)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	642	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SPTN5_HUMAN
NC score	0.017412 (rank : 104)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

KIF3A_MOUSE
NC score	0.017033 (rank : 105)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	715	Shared Neighborhood Hits	48
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF17_MOUSE
NC score	0.016904 (rank : 106)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	452	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

ZMYM3_HUMAN
NC score	0.015528 (rank : 107)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	223	Shared Neighborhood Hits	11
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

COHA1_MOUSE
NC score	0.014382 (rank : 108)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

AFF1_HUMAN
NC score	0.013617 (rank : 109)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	9
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

KIF3A_HUMAN
NC score	0.013476 (rank : 110)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	704	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

ZCPW1_HUMAN
NC score	0.013251 (rank : 111)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

FYV1_HUMAN
NC score	0.012252 (rank : 112)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

LAMA5_MOUSE
NC score	0.012164 (rank : 113)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PEX14_HUMAN
NC score	0.011854 (rank : 114)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

RGS3_MOUSE
NC score	0.011237 (rank : 115)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	1621	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

FCRL5_HUMAN
NC score	0.010371 (rank : 116)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

K0256_MOUSE
NC score	0.008666 (rank : 117)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

KCTD8_HUMAN
NC score	0.007784 (rank : 118)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZWB6	Gene names	KCTD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

BASI_MOUSE
NC score	0.007192 (rank : 119)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

GTF2I_HUMAN
NC score	0.006496 (rank : 120)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

PB1_HUMAN
NC score	0.006088 (rank : 121)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

DMBT1_MOUSE
NC score	0.003574 (rank : 122)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

LYN_HUMAN
NC score	0.002266 (rank : 123)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	1022	Shared Neighborhood Hits	6
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SIP1_HUMAN
NC score	0.001977 (rank : 124)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	832	Shared Neighborhood Hits	10
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
NC score	0.001916 (rank : 125)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	870	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

DMPK_HUMAN
NC score	0.001675 (rank : 126)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	944	Shared Neighborhood Hits	21
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

TSP2_HUMAN
NC score	0.000811 (rank : 127)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	359	Shared Neighborhood Hits	3
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

LYN_MOUSE
NC score	0.000654 (rank : 128)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	1023	Shared Neighborhood Hits	6
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SPEG_MOUSE
NC score	-0.001000 (rank : 129)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	1959	Shared Neighborhood Hits	18
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZNF91_HUMAN
NC score	-0.001822 (rank : 130)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	797	Shared Neighborhood Hits	7
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

ZNF14_HUMAN
NC score	-0.002021 (rank : 131)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	760	Shared Neighborhood Hits	10
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

ZN559_HUMAN
NC score	-0.002052 (rank : 132)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	746	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BR84	Gene names	ZNF559
Domain Architecture	No domain graphic available
Description	Zinc finger protein 559.

ZN228_HUMAN
NC score	-0.002081 (rank : 133)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	775	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJU3, Q9HCA7	Gene names	ZNF228
Domain Architecture
Description	Zinc finger protein 228.