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Network neighborhood for query Sequence : RGP2_HUMAN

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RGP2_HUMAN
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RGP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

SI1L3_HUMAN
θ value	1.45929e-58 (rank : 2)	NC score	0.874658 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	305	Shared Neighborhood Hits	17
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SI1L1_MOUSE
θ value	5.54529e-58 (rank : 3)	NC score	0.882084 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L1_HUMAN
θ value	9.45883e-58 (rank : 4)	NC score	0.883970 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L2_HUMAN
θ value	1.61343e-57 (rank : 5)	NC score	0.884649 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	2.32979e-56 (rank : 6)	NC score	0.885562 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	124	Shared Neighborhood Hits	12
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SIPA1_MOUSE
θ value	6.77864e-56 (rank : 7)	NC score	0.894291 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SIPA1_HUMAN
θ value	2.84797e-54 (rank : 8)	NC score	0.880920 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	250	Shared Neighborhood Hits	17
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

GRIPE_HUMAN
θ value	4.91457e-14 (rank : 9)	NC score	0.542469 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
θ value	1.42992e-13 (rank : 10)	NC score	0.533043 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
θ value	7.09661e-13 (rank : 11)	NC score	0.530450 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
θ value	1.2105e-12 (rank : 12)	NC score	0.512755 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

ASXL1_HUMAN
θ value	0.00509761 (rank : 13)	NC score	0.069635 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CYLC1_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.047529 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	7
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MUC5B_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.025623 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	1020	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NC6IP_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.048827 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

SRRM2_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.057034 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	1296	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BLM_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.024281 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

CAC1G_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.018434 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	587	Shared Neighborhood Hits	10
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

PGCA_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.017376 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	643	Shared Neighborhood Hits	8
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MARK2_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.004000 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	1018	Shared Neighborhood Hits	15
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

OBSCN_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.005547 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	1931	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SALL1_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.004499 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	821	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

TCF20_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.030670 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

GPSM2_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.025108 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

KI67_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.036574 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CJ012_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.034902 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

IF16_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.023343 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

MAP4_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.030796 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PHF22_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.028558 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SRRM1_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.037513 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PHLPP_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.011741 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	604	Shared Neighborhood Hits	6
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

4ET_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.020420 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

BSN_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.025410 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MILK2_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.013562 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	457	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

SRRM2_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.047016 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	1470	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARA_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.024089 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	1626	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ATBF1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.010043 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	1547	Shared Neighborhood Hits	16
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.009989 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	1841	Shared Neighborhood Hits	19
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

AXN1_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.011589 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

DPOLZ_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.014581 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

MELK_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.001457 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	860	Shared Neighborhood Hits	6
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

NOLC1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.027248 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	452	Shared Neighborhood Hits	16
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PHLPP_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.011231 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	394	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PI51C_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.010950 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

TCOF_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.024999 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	471	Shared Neighborhood Hits	20
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

HXA2_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.003718 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

MYST4_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.014784 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	671	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

T240L_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.013810 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ATX2L_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.011032 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	401	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CAD23_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.002029 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

K0310_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.022180 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

NFIP2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.017290 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

NRK_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.001111 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	931	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

AKA12_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.012470 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DDX51_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.005947 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

GPSM2_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.018079 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

RRBP1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.004235 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	1650	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SRPK1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.004263 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

ZEP2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.002923 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	964	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

APBA2_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.058182 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.058526 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.056976 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN2_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.063012 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	346	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.053860 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

Hits sorted by NC score

RGP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

SIPA1_MOUSE
NC score	0.894291 (rank : 2)	θ value	6.77864e-56 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SI1L2_MOUSE
NC score	0.885562 (rank : 3)	θ value	2.32979e-56 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	124	Shared Neighborhood Hits	12
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_HUMAN
NC score	0.884649 (rank : 4)	θ value	1.61343e-57 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L1_HUMAN
NC score	0.883970 (rank : 5)	θ value	9.45883e-58 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
NC score	0.882084 (rank : 6)	θ value	5.54529e-58 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SIPA1_HUMAN
NC score	0.880920 (rank : 7)	θ value	2.84797e-54 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	250	Shared Neighborhood Hits	17
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SI1L3_HUMAN
NC score	0.874658 (rank : 8)	θ value	1.45929e-58 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	305	Shared Neighborhood Hits	17
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

GRIPE_HUMAN
NC score	0.542469 (rank : 9)	θ value	4.91457e-14 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
NC score	0.533043 (rank : 10)	θ value	1.42992e-13 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
NC score	0.530450 (rank : 11)	θ value	7.09661e-13 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
NC score	0.512755 (rank : 12)	θ value	1.2105e-12 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

ASXL1_HUMAN
NC score	0.069635 (rank : 13)	θ value	0.00509761 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

SHAN2_HUMAN
NC score	0.063012 (rank : 14)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	346	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

APBA2_MOUSE
NC score	0.058526 (rank : 15)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.058182 (rank : 16)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

SRRM2_HUMAN
NC score	0.057034 (rank : 17)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	1296	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

APBA3_MOUSE
NC score	0.056976 (rank : 18)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN2_MOUSE
NC score	0.053860 (rank : 19)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NC6IP_HUMAN
NC score	0.048827 (rank : 20)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

CYLC1_HUMAN
NC score	0.047529 (rank : 21)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	7
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

SRRM2_MOUSE
NC score	0.047016 (rank : 22)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	1470	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM1_HUMAN
NC score	0.037513 (rank : 23)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

KI67_HUMAN
NC score	0.036574 (rank : 24)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CJ012_HUMAN
NC score	0.034902 (rank : 25)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

MAP4_MOUSE
NC score	0.030796 (rank : 26)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TCF20_MOUSE
NC score	0.030670 (rank : 27)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PHF22_HUMAN
NC score	0.028558 (rank : 28)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

NOLC1_HUMAN
NC score	0.027248 (rank : 29)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	452	Shared Neighborhood Hits	16
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MUC5B_HUMAN
NC score	0.025623 (rank : 30)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	1020	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

BSN_MOUSE
NC score	0.025410 (rank : 31)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GPSM2_HUMAN
NC score	0.025108 (rank : 32)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

TCOF_MOUSE
NC score	0.024999 (rank : 33)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	471	Shared Neighborhood Hits	20
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

BLM_HUMAN
NC score	0.024281 (rank : 34)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

TARA_HUMAN
NC score	0.024089 (rank : 35)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	1626	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

IF16_HUMAN
NC score	0.023343 (rank : 36)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

K0310_HUMAN
NC score	0.022180 (rank : 37)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

4ET_HUMAN
NC score	0.020420 (rank : 38)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CAC1G_HUMAN
NC score	0.018434 (rank : 39)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	587	Shared Neighborhood Hits	10
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GPSM2_MOUSE
NC score	0.018079 (rank : 40)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

PGCA_MOUSE
NC score	0.017376 (rank : 41)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	643	Shared Neighborhood Hits	8
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

NFIP2_HUMAN
NC score	0.017290 (rank : 42)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

MYST4_HUMAN
NC score	0.014784 (rank : 43)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	671	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

DPOLZ_HUMAN
NC score	0.014581 (rank : 44)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

T240L_MOUSE
NC score	0.013810 (rank : 45)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

MILK2_HUMAN
NC score	0.013562 (rank : 46)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	457	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

AKA12_HUMAN
NC score	0.012470 (rank : 47)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

PHLPP_HUMAN
NC score	0.011741 (rank : 48)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	604	Shared Neighborhood Hits	6
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

AXN1_HUMAN
NC score	0.011589 (rank : 49)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

PHLPP_MOUSE
NC score	0.011231 (rank : 50)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	394	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

ATX2L_MOUSE
NC score	0.011032 (rank : 51)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	401	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

PI51C_HUMAN
NC score	0.010950 (rank : 52)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

ATBF1_HUMAN
NC score	0.010043 (rank : 53)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	1547	Shared Neighborhood Hits	16
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
NC score	0.009989 (rank : 54)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	1841	Shared Neighborhood Hits	19
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DDX51_HUMAN
NC score	0.005947 (rank : 55)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

OBSCN_HUMAN
NC score	0.005547 (rank : 56)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	1931	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SALL1_HUMAN
NC score	0.004499 (rank : 57)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	821	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

SRPK1_HUMAN
NC score	0.004263 (rank : 58)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

RRBP1_MOUSE
NC score	0.004235 (rank : 59)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	1650	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

MARK2_MOUSE
NC score	0.004000 (rank : 60)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	1018	Shared Neighborhood Hits	15
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

HXA2_HUMAN
NC score	0.003718 (rank : 61)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

ZEP2_MOUSE
NC score	0.002923 (rank : 62)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	964	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

CAD23_MOUSE
NC score	0.002029 (rank : 63)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

MELK_MOUSE
NC score	0.001457 (rank : 64)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	860	Shared Neighborhood Hits	6
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

NRK_HUMAN
NC score	0.001111 (rank : 65)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	931	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).