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Network neighborhood for query Sequence : 4ET_HUMAN

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4ET_HUMAN
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

4ET_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

4ET_MOUSE
θ value	0 (rank : 2)	NC score	0.962405 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CENPE_HUMAN
θ value	0.0193708 (rank : 3)	NC score	0.033381 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CJ078_MOUSE
θ value	0.0431538 (rank : 4)	NC score	0.095132 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	559	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

YLPM1_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.081734 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	670	Shared Neighborhood Hits	26
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZFHX2_HUMAN
θ value	0.0736092 (rank : 6)	NC score	0.040044 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	1178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

BAZ2A_HUMAN
θ value	0.0961366 (rank : 7)	NC score	0.058116 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	780	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BPA1_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.047419 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	1477	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.045950 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	1480	Shared Neighborhood Hits	22
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGA2_MOUSE
θ value	0.125558 (rank : 10)	NC score	0.058555 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	944	Shared Neighborhood Hits	22
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

YLPM1_MOUSE
θ value	0.163984 (rank : 11)	NC score	0.087993 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SPT5H_HUMAN
θ value	0.21417 (rank : 12)	NC score	0.073457 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	436	Shared Neighborhood Hits	15
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.21417 (rank : 13)	NC score	0.073644 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	437	Shared Neighborhood Hits	16
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

GOGA3_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.041868 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	1317	Shared Neighborhood Hits	23
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

SF3A2_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.061770 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

AKA10_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.067688 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

PO6F2_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.037342 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	618	Shared Neighborhood Hits	16
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

MLL2_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.035250 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	42
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZN281_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.005661 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	745	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2X9, Q9NY92	Gene names	ZNF281, GZP1, ZBP99
Domain Architecture	No domain graphic available
Description	Zinc finger protein 281 (Zinc finger DNA-binding protein 99) (Transcription factor ZBP-99) (GC-box-binding zinc finger protein 1).

CCDC4_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.061514 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

CPNE5_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.021892 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CROCC_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.043644 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	1409	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA2_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.054338 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	856	Shared Neighborhood Hits	22
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

LEF1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.057802 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	150	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

NUP93_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.073059 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1F7, Q14705	Gene names	NUP93, KIAA0095
Domain Architecture
Description	Nuclear pore complex protein Nup93 (Nucleoporin Nup93) (93 kDa nucleoporin).

NUP93_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.073280 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ71, Q3TED9, Q8BIK7, Q8K1R4, Q8R592	Gene names	Nup93, Cip4, Kiaa0095
Domain Architecture
Description	Nuclear pore complex protein Nup93 (Nucleoporin Nup93) (93 kDa nucleoporin) (CBP-interacting protein 4).

WWP1_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.018148 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ARS2_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.056684 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CROCC_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.037470 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	1460	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FEZ2_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.058321 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

LEF1_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.060363 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

SOS1_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.042230 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SRRM2_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.036830 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

THSD1_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.047879 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

WNK2_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.010714 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	1407	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZEP1_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.014702 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	1036	Shared Neighborhood Hits	20
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

CENPK_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.045545 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	149	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

TAF1C_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.037382 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

AMOT_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.035781 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	712	Shared Neighborhood Hits	28
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CCD21_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.030050 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	1228	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MDC1_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.034946 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	1446	Shared Neighborhood Hits	41
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NIN_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.032603 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	1416	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

SOS1_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.032024 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

CKAP2_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.040393 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

GOGA3_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.033631 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	1437	Shared Neighborhood Hits	20
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HCFC2_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.019064 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HD_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.037911 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

SF3A2_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.053172 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SSH2_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.020788 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

TCF7_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.033432 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	186	Shared Neighborhood Hits	9
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

HD_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.036893 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

RGP2_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.020420 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

SNX18_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.017358 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	207	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SYN3_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.019804 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

TBCD5_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.023511 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

ASXL1_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.021415 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BPAEA_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.040570 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	1369	Shared Neighborhood Hits	22
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CIKS_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.036780 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

CPNE5_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.017875 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

MACF1_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.037469 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	1313	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

SFPQ_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.018789 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	986	Shared Neighborhood Hits	22
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

AF9_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.023182 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CBL_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.016955 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	426	Shared Neighborhood Hits	9
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CHD4_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.011892 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	408	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CTGE2_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.028417 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	594	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

MEF2D_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.015218 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

NCOA6_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.031076 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	1202	Shared Neighborhood Hits	34
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

P3H1_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.016822 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

PKHG1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.015697 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

WNK1_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.008701 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	1158	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ACM2_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.000773 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	905	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ4	Gene names	Chrm2, Chrm-2
Domain Architecture
Description	Muscarinic acetylcholine receptor M2.

CK024_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.022571 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CTGE5_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.027248 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	928	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

G3BP_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.012294 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GPR64_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.007417 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

HIPK3_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.001915 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	857	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

K1267_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.026488 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

K1267_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.025328 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

K1958_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.015669 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

N4BP2_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.028085 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

NR4A2_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.006950 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.006953 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

PMS2_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.015091 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

RNPC1_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.018191 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

SF3B2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.021739 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SN1L1_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.000723 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

UBP36_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.008395 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

ADA12_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.007266 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

COA2_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.011137 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

CS007_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.016130 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NCOA5_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.017371 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

P3H1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.014348 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

PERQ1_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.021531 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	215	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

PHAR1_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.011082 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

PLAL2_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.000622 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	734	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPG8, Q92584	Gene names	PLAGL2, KIAA0198
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL2 (Pleiomorphic adenoma-like protein 2).

TARA_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.030589 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	1133	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

Hits sorted by NC score

4ET_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

4ET_MOUSE
NC score	0.962405 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CJ078_MOUSE
NC score	0.095132 (rank : 3)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	559	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

YLPM1_MOUSE
NC score	0.087993 (rank : 4)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

YLPM1_HUMAN
NC score	0.081734 (rank : 5)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	670	Shared Neighborhood Hits	26
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SPT5H_MOUSE
NC score	0.073644 (rank : 6)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	437	Shared Neighborhood Hits	16
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.073457 (rank : 7)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	436	Shared Neighborhood Hits	15
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

NUP93_MOUSE
NC score	0.073280 (rank : 8)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ71, Q3TED9, Q8BIK7, Q8K1R4, Q8R592	Gene names	Nup93, Cip4, Kiaa0095
Domain Architecture
Description	Nuclear pore complex protein Nup93 (Nucleoporin Nup93) (93 kDa nucleoporin) (CBP-interacting protein 4).

NUP93_HUMAN
NC score	0.073059 (rank : 9)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1F7, Q14705	Gene names	NUP93, KIAA0095
Domain Architecture
Description	Nuclear pore complex protein Nup93 (Nucleoporin Nup93) (93 kDa nucleoporin).

AKA10_MOUSE
NC score	0.067688 (rank : 10)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SF3A2_HUMAN
NC score	0.061770 (rank : 11)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CCDC4_HUMAN
NC score	0.061514 (rank : 12)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

LEF1_MOUSE
NC score	0.060363 (rank : 13)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

GOGA2_MOUSE
NC score	0.058555 (rank : 14)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	944	Shared Neighborhood Hits	22
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

FEZ2_MOUSE
NC score	0.058321 (rank : 15)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

BAZ2A_HUMAN
NC score	0.058116 (rank : 16)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	780	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

LEF1_HUMAN
NC score	0.057802 (rank : 17)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	150	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

ARS2_MOUSE
NC score	0.056684 (rank : 18)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

GOGA2_HUMAN
NC score	0.054338 (rank : 19)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	856	Shared Neighborhood Hits	22
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

SF3A2_MOUSE
NC score	0.053172 (rank : 20)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

THSD1_HUMAN
NC score	0.047879 (rank : 21)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

BPA1_MOUSE
NC score	0.047419 (rank : 22)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	1477	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
NC score	0.045950 (rank : 23)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	1480	Shared Neighborhood Hits	22
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPK_MOUSE
NC score	0.045545 (rank : 24)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	149	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

CROCC_HUMAN
NC score	0.043644 (rank : 25)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	1409	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SOS1_MOUSE
NC score	0.042230 (rank : 26)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

GOGA3_HUMAN
NC score	0.041868 (rank : 27)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	1317	Shared Neighborhood Hits	23
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

BPAEA_HUMAN
NC score	0.040570 (rank : 28)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	1369	Shared Neighborhood Hits	22
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CKAP2_HUMAN
NC score	0.040393 (rank : 29)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

ZFHX2_HUMAN
NC score	0.040044 (rank : 30)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	1178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

HD_HUMAN
NC score	0.037911 (rank : 31)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

CROCC_MOUSE
NC score	0.037470 (rank : 32)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	1460	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MACF1_MOUSE
NC score	0.037469 (rank : 33)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	1313	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

TAF1C_HUMAN
NC score	0.037382 (rank : 34)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

PO6F2_HUMAN
NC score	0.037342 (rank : 35)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	618	Shared Neighborhood Hits	16
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

HD_MOUSE
NC score	0.036893 (rank : 36)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

SRRM2_MOUSE
NC score	0.036830 (rank : 37)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CIKS_HUMAN
NC score	0.036780 (rank : 38)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

AMOT_HUMAN
NC score	0.035781 (rank : 39)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	712	Shared Neighborhood Hits	28
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

MLL2_HUMAN
NC score	0.035250 (rank : 40)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	42
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MDC1_HUMAN
NC score	0.034946 (rank : 41)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	1446	Shared Neighborhood Hits	41
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GOGA3_MOUSE
NC score	0.033631 (rank : 42)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	1437	Shared Neighborhood Hits	20
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

TCF7_HUMAN
NC score	0.033432 (rank : 43)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	186	Shared Neighborhood Hits	9
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

CENPE_HUMAN
NC score	0.033381 (rank : 44)	θ value	0.0193708 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

NIN_HUMAN
NC score	0.032603 (rank : 45)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	1416	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

SOS1_HUMAN
NC score	0.032024 (rank : 46)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

NCOA6_HUMAN
NC score	0.031076 (rank : 47)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	1202	Shared Neighborhood Hits	34
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TARA_MOUSE
NC score	0.030589 (rank : 48)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	1133	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCD21_HUMAN
NC score	0.030050 (rank : 49)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	1228	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CTGE2_HUMAN
NC score	0.028417 (rank : 50)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	594	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

N4BP2_HUMAN
NC score	0.028085 (rank : 51)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

CTGE5_MOUSE
NC score	0.027248 (rank : 52)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	928	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

K1267_HUMAN
NC score	0.026488 (rank : 53)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

K1267_MOUSE
NC score	0.025328 (rank : 54)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

TBCD5_HUMAN
NC score	0.023511 (rank : 55)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

AF9_HUMAN
NC score	0.023182 (rank : 56)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CK024_MOUSE
NC score	0.022571 (rank : 57)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CPNE5_MOUSE
NC score	0.021892 (rank : 58)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

SF3B2_HUMAN
NC score	0.021739 (rank : 59)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

PERQ1_MOUSE
NC score	0.021531 (rank : 60)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	215	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

ASXL1_MOUSE
NC score	0.021415 (rank : 61)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

SSH2_HUMAN
NC score	0.020788 (rank : 62)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

RGP2_HUMAN
NC score	0.020420 (rank : 63)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

SYN3_MOUSE
NC score	0.019804 (rank : 64)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

HCFC2_HUMAN
NC score	0.019064 (rank : 65)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

SFPQ_HUMAN
NC score	0.018789 (rank : 66)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	986	Shared Neighborhood Hits	22
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

RNPC1_MOUSE
NC score	0.018191 (rank : 67)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

WWP1_MOUSE
NC score	0.018148 (rank : 68)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

CPNE5_HUMAN
NC score	0.017875 (rank : 69)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

NCOA5_MOUSE
NC score	0.017371 (rank : 70)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

SNX18_HUMAN
NC score	0.017358 (rank : 71)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	207	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

CBL_MOUSE
NC score	0.016955 (rank : 72)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	426	Shared Neighborhood Hits	9
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

P3H1_HUMAN
NC score	0.016822 (rank : 73)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

CS007_HUMAN
NC score	0.016130 (rank : 74)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PKHG1_HUMAN
NC score	0.015697 (rank : 75)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

K1958_HUMAN
NC score	0.015669 (rank : 76)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

MEF2D_MOUSE
NC score	0.015218 (rank : 77)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

PMS2_MOUSE
NC score	0.015091 (rank : 78)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

ZEP1_HUMAN
NC score	0.014702 (rank : 79)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	1036	Shared Neighborhood Hits	20
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

P3H1_MOUSE
NC score	0.014348 (rank : 80)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

G3BP_HUMAN
NC score	0.012294 (rank : 81)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

CHD4_MOUSE
NC score	0.011892 (rank : 82)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	408	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

COA2_HUMAN
NC score	0.011137 (rank : 83)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

PHAR1_MOUSE
NC score	0.011082 (rank : 84)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

WNK2_HUMAN
NC score	0.010714 (rank : 85)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	1407	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK1_HUMAN
NC score	0.008701 (rank : 86)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	1158	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

UBP36_HUMAN
NC score	0.008395 (rank : 87)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

GPR64_HUMAN
NC score	0.007417 (rank : 88)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

ADA12_MOUSE
NC score	0.007266 (rank : 89)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

NR4A2_MOUSE
NC score	0.006953 (rank : 90)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A2_HUMAN
NC score	0.006950 (rank : 91)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

ZN281_HUMAN
NC score	0.005661 (rank : 92)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	745	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2X9, Q9NY92	Gene names	ZNF281, GZP1, ZBP99
Domain Architecture	No domain graphic available
Description	Zinc finger protein 281 (Zinc finger DNA-binding protein 99) (Transcription factor ZBP-99) (GC-box-binding zinc finger protein 1).

HIPK3_MOUSE
NC score	0.001915 (rank : 93)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	857	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

ACM2_MOUSE
NC score	0.000773 (rank : 94)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	905	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ4	Gene names	Chrm2, Chrm-2
Domain Architecture
Description	Muscarinic acetylcholine receptor M2.

SN1L1_HUMAN
NC score	0.000723 (rank : 95)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

PLAL2_HUMAN
NC score	0.000622 (rank : 96)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	734	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPG8, Q92584	Gene names	PLAGL2, KIAA0198
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL2 (Pleiomorphic adenoma-like protein 2).