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Network neighborhood for query Sequence : ZO1_HUMAN

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ZO1_HUMAN
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZO1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	474	Target Neighborhood Hits	474	Shared Neighborhood Hits	474
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	0 (rank : 2)	NC score	0.975693 (rank : 2)
Query Neighborhood Hits	474	Target Neighborhood Hits	453	Shared Neighborhood Hits	280
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	0 (rank : 3)	NC score	0.914099 (rank : 5)
Query Neighborhood Hits	474	Target Neighborhood Hits	289	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	0 (rank : 4)	NC score	0.917773 (rank : 3)
Query Neighborhood Hits	474	Target Neighborhood Hits	296	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
θ value	3.97187e-173 (rank : 5)	NC score	0.916742 (rank : 4)
Query Neighborhood Hits	474	Target Neighborhood Hits	219	Shared Neighborhood Hits	181
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
θ value	4.11978e-162 (rank : 6)	NC score	0.912380 (rank : 6)
Query Neighborhood Hits	474	Target Neighborhood Hits	224	Shared Neighborhood Hits	182
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

DLG1_MOUSE
θ value	9.52487e-34 (rank : 7)	NC score	0.709380 (rank : 12)
Query Neighborhood Hits	474	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG5_HUMAN
θ value	1.24399e-33 (rank : 8)	NC score	0.531024 (rank : 32)
Query Neighborhood Hits	474	Target Neighborhood Hits	1088	Shared Neighborhood Hits	210
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DLG1_HUMAN
θ value	2.77131e-33 (rank : 9)	NC score	0.708743 (rank : 13)
Query Neighborhood Hits	474	Target Neighborhood Hits	290	Shared Neighborhood Hits	171
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG4_MOUSE
θ value	1.0531e-32 (rank : 10)	NC score	0.717925 (rank : 7)
Query Neighborhood Hits	474	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
θ value	1.37539e-32 (rank : 11)	NC score	0.717021 (rank : 8)
Query Neighborhood Hits	474	Target Neighborhood Hits	286	Shared Neighborhood Hits	175
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_HUMAN
θ value	1.79631e-32 (rank : 12)	NC score	0.712397 (rank : 10)
Query Neighborhood Hits	474	Target Neighborhood Hits	279	Shared Neighborhood Hits	171
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	5.22648e-32 (rank : 13)	NC score	0.712446 (rank : 9)
Query Neighborhood Hits	474	Target Neighborhood Hits	271	Shared Neighborhood Hits	171
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	8.91499e-32 (rank : 14)	NC score	0.709921 (rank : 11)
Query Neighborhood Hits	474	Target Neighborhood Hits	269	Shared Neighborhood Hits	172
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	4.89182e-30 (rank : 15)	NC score	0.708525 (rank : 14)
Query Neighborhood Hits	474	Target Neighborhood Hits	274	Shared Neighborhood Hits	172
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

INADL_MOUSE
θ value	7.82807e-20 (rank : 16)	NC score	0.632735 (rank : 16)
Query Neighborhood Hits	474	Target Neighborhood Hits	290	Shared Neighborhood Hits	183
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

PTN13_MOUSE
θ value	4.02038e-16 (rank : 17)	NC score	0.356876 (rank : 97)
Query Neighborhood Hits	474	Target Neighborhood Hits	426	Shared Neighborhood Hits	174
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

MPDZ_MOUSE
θ value	2.60593e-15 (rank : 18)	NC score	0.600347 (rank : 18)
Query Neighborhood Hits	474	Target Neighborhood Hits	298	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

UNC5C_HUMAN
θ value	1.68911e-14 (rank : 19)	NC score	0.218012 (rank : 149)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	1.68911e-14 (rank : 20)	NC score	0.218237 (rank : 148)
Query Neighborhood Hits	474	Target Neighborhood Hits	225	Shared Neighborhood Hits	25
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

MPP5_HUMAN
θ value	4.91457e-14 (rank : 21)	NC score	0.525222 (rank : 35)
Query Neighborhood Hits	474	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPDZ_HUMAN
θ value	8.38298e-14 (rank : 22)	NC score	0.598871 (rank : 19)
Query Neighborhood Hits	474	Target Neighborhood Hits	261	Shared Neighborhood Hits	176
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPP5_MOUSE
θ value	1.86753e-13 (rank : 23)	NC score	0.524434 (rank : 41)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

UNC5B_MOUSE
θ value	1.58096e-12 (rank : 24)	NC score	0.213826 (rank : 151)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
θ value	2.0648e-12 (rank : 25)	NC score	0.212683 (rank : 152)
Query Neighborhood Hits	474	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

LAP4_HUMAN
θ value	2.28291e-11 (rank : 26)	NC score	0.403317 (rank : 84)
Query Neighborhood Hits	474	Target Neighborhood Hits	608	Shared Neighborhood Hits	195
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PTN13_HUMAN
θ value	2.28291e-11 (rank : 27)	NC score	0.361478 (rank : 94)
Query Neighborhood Hits	474	Target Neighborhood Hits	471	Shared Neighborhood Hits	178
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

UNC5D_MOUSE
θ value	2.98157e-11 (rank : 28)	NC score	0.203142 (rank : 158)
Query Neighborhood Hits	474	Target Neighborhood Hits	268	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

MAGI1_HUMAN
θ value	6.64225e-11 (rank : 29)	NC score	0.524655 (rank : 38)
Query Neighborhood Hits	474	Target Neighborhood Hits	388	Shared Neighborhood Hits	190
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

UNC5A_MOUSE
θ value	6.64225e-11 (rank : 30)	NC score	0.207214 (rank : 156)
Query Neighborhood Hits	474	Target Neighborhood Hits	203	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PZRN3_HUMAN
θ value	8.67504e-11 (rank : 31)	NC score	0.489577 (rank : 60)
Query Neighborhood Hits	474	Target Neighborhood Hits	461	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	1.133e-10 (rank : 32)	NC score	0.487547 (rank : 61)
Query Neighborhood Hits	474	Target Neighborhood Hits	447	Shared Neighborhood Hits	152
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

UNC5A_HUMAN
θ value	1.133e-10 (rank : 33)	NC score	0.228957 (rank : 142)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5D_HUMAN
θ value	1.47974e-10 (rank : 34)	NC score	0.201273 (rank : 161)
Query Neighborhood Hits	474	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

INADL_HUMAN
θ value	1.9326e-10 (rank : 35)	NC score	0.615185 (rank : 17)
Query Neighborhood Hits	474	Target Neighborhood Hits	260	Shared Neighborhood Hits	173
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LAP4_MOUSE
θ value	1.9326e-10 (rank : 36)	NC score	0.401262 (rank : 88)
Query Neighborhood Hits	474	Target Neighborhood Hits	590	Shared Neighborhood Hits	199
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PDZD2_HUMAN
θ value	2.52405e-10 (rank : 37)	NC score	0.559934 (rank : 22)
Query Neighborhood Hits	474	Target Neighborhood Hits	772	Shared Neighborhood Hits	239
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LNX2_MOUSE
θ value	7.34386e-10 (rank : 38)	NC score	0.552329 (rank : 24)
Query Neighborhood Hits	474	Target Neighborhood Hits	407	Shared Neighborhood Hits	171
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

EM55_MOUSE
θ value	3.64472e-09 (rank : 39)	NC score	0.440485 (rank : 73)
Query Neighborhood Hits	474	Target Neighborhood Hits	221	Shared Neighborhood Hits	113
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

LNX2_HUMAN
θ value	3.64472e-09 (rank : 40)	NC score	0.535610 (rank : 29)
Query Neighborhood Hits	474	Target Neighborhood Hits	389	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MAGI1_MOUSE
θ value	3.64472e-09 (rank : 41)	NC score	0.520105 (rank : 45)
Query Neighborhood Hits	474	Target Neighborhood Hits	403	Shared Neighborhood Hits	196
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PZRN4_HUMAN
θ value	4.76016e-09 (rank : 42)	NC score	0.490703 (rank : 58)
Query Neighborhood Hits	474	Target Neighborhood Hits	438	Shared Neighborhood Hits	155
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

MAGI2_MOUSE
θ value	1.06045e-08 (rank : 43)	NC score	0.507013 (rank : 51)
Query Neighborhood Hits	474	Target Neighborhood Hits	370	Shared Neighborhood Hits	197
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LNX1_HUMAN
θ value	3.08544e-08 (rank : 44)	NC score	0.534928 (rank : 30)
Query Neighborhood Hits	474	Target Neighborhood Hits	379	Shared Neighborhood Hits	156
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

CAR11_HUMAN
θ value	4.0297e-08 (rank : 45)	NC score	0.227183 (rank : 144)
Query Neighborhood Hits	474	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

LNX1_MOUSE
θ value	4.0297e-08 (rank : 46)	NC score	0.539244 (rank : 28)
Query Neighborhood Hits	474	Target Neighborhood Hits	377	Shared Neighborhood Hits	162
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDZ11_MOUSE
θ value	1.99992e-07 (rank : 47)	NC score	0.589551 (rank : 20)
Query Neighborhood Hits	474	Target Neighborhood Hits	154	Shared Neighborhood Hits	134
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MAGI2_HUMAN
θ value	2.61198e-07 (rank : 48)	NC score	0.497904 (rank : 55)
Query Neighborhood Hits	474	Target Neighborhood Hits	373	Shared Neighborhood Hits	184
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

CAR14_HUMAN
θ value	3.41135e-07 (rank : 49)	NC score	0.246909 (rank : 132)
Query Neighborhood Hits	474	Target Neighborhood Hits	449	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CAR14_MOUSE
θ value	3.41135e-07 (rank : 50)	NC score	0.219100 (rank : 147)
Query Neighborhood Hits	474	Target Neighborhood Hits	526	Shared Neighborhood Hits	42
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

PDZ11_HUMAN
θ value	4.45536e-07 (rank : 51)	NC score	0.588486 (rank : 21)
Query Neighborhood Hits	474	Target Neighborhood Hits	160	Shared Neighborhood Hits	138
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

CAR10_MOUSE
θ value	7.59969e-07 (rank : 52)	NC score	0.208917 (rank : 155)
Query Neighborhood Hits	474	Target Neighborhood Hits	407	Shared Neighborhood Hits	32
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

SNTG2_HUMAN
θ value	7.59969e-07 (rank : 53)	NC score	0.500779 (rank : 53)
Query Neighborhood Hits	474	Target Neighborhood Hits	191	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTA1_HUMAN
θ value	9.92553e-07 (rank : 54)	NC score	0.470867 (rank : 66)
Query Neighborhood Hits	474	Target Neighborhood Hits	186	Shared Neighborhood Hits	150
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

EM55_HUMAN
θ value	1.69304e-06 (rank : 55)	NC score	0.430924 (rank : 76)
Query Neighborhood Hits	474	Target Neighborhood Hits	228	Shared Neighborhood Hits	115
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SNTA1_MOUSE
θ value	1.69304e-06 (rank : 56)	NC score	0.466804 (rank : 67)
Query Neighborhood Hits	474	Target Neighborhood Hits	170	Shared Neighborhood Hits	145
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTG2_MOUSE
θ value	1.69304e-06 (rank : 57)	NC score	0.474806 (rank : 65)
Query Neighborhood Hits	474	Target Neighborhood Hits	176	Shared Neighborhood Hits	147
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDZD1_MOUSE
θ value	2.88788e-06 (rank : 58)	NC score	0.492023 (rank : 57)
Query Neighborhood Hits	474	Target Neighborhood Hits	191	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SYJ2B_HUMAN
θ value	2.88788e-06 (rank : 59)	NC score	0.643150 (rank : 15)
Query Neighborhood Hits	474	Target Neighborhood Hits	162	Shared Neighborhood Hits	146
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

MPP2_MOUSE
θ value	3.77169e-06 (rank : 60)	NC score	0.421503 (rank : 78)
Query Neighborhood Hits	474	Target Neighborhood Hits	189	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

WHRN_MOUSE
θ value	3.77169e-06 (rank : 61)	NC score	0.545912 (rank : 26)
Query Neighborhood Hits	474	Target Neighborhood Hits	412	Shared Neighborhood Hits	197
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LRRC7_HUMAN
θ value	4.92598e-06 (rank : 62)	NC score	0.243461 (rank : 135)
Query Neighborhood Hits	474	Target Neighborhood Hits	423	Shared Neighborhood Hits	123
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	4.92598e-06 (rank : 63)	NC score	0.242746 (rank : 136)
Query Neighborhood Hits	474	Target Neighborhood Hits	416	Shared Neighborhood Hits	123
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

WHRN_HUMAN
θ value	6.43352e-06 (rank : 64)	NC score	0.549991 (rank : 25)
Query Neighborhood Hits	474	Target Neighborhood Hits	325	Shared Neighborhood Hits	187
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

LAP2_HUMAN
θ value	1.43324e-05 (rank : 65)	NC score	0.234517 (rank : 138)
Query Neighborhood Hits	474	Target Neighborhood Hits	499	Shared Neighborhood Hits	122
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MPP2_HUMAN
θ value	1.87187e-05 (rank : 66)	NC score	0.418007 (rank : 81)
Query Neighborhood Hits	474	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

NEB2_HUMAN
θ value	2.44474e-05 (rank : 67)	NC score	0.338981 (rank : 106)
Query Neighborhood Hits	474	Target Neighborhood Hits	883	Shared Neighborhood Hits	151
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	2.44474e-05 (rank : 68)	NC score	0.334379 (rank : 108)
Query Neighborhood Hits	474	Target Neighborhood Hits	889	Shared Neighborhood Hits	144
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZK4_HUMAN
θ value	2.44474e-05 (rank : 69)	NC score	0.402804 (rank : 85)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	120
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

LAP2_MOUSE
θ value	4.1701e-05 (rank : 70)	NC score	0.225975 (rank : 145)
Query Neighborhood Hits	474	Target Neighborhood Hits	482	Shared Neighborhood Hits	117
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

USH1C_MOUSE
θ value	4.1701e-05 (rank : 71)	NC score	0.515306 (rank : 49)
Query Neighborhood Hits	474	Target Neighborhood Hits	557	Shared Neighborhood Hits	195
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

CAR10_HUMAN
θ value	5.44631e-05 (rank : 72)	NC score	0.169764 (rank : 171)
Query Neighborhood Hits	474	Target Neighborhood Hits	569	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

IL16_HUMAN
θ value	5.44631e-05 (rank : 73)	NC score	0.519684 (rank : 46)
Query Neighborhood Hits	474	Target Neighborhood Hits	207	Shared Neighborhood Hits	142
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTG1_MOUSE
θ value	5.44631e-05 (rank : 74)	NC score	0.456335 (rank : 68)
Query Neighborhood Hits	474	Target Neighborhood Hits	179	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

CSKP_HUMAN
θ value	7.1131e-05 (rank : 75)	NC score	0.142272 (rank : 183)
Query Neighborhood Hits	474	Target Neighborhood Hits	1022	Shared Neighborhood Hits	122
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

GRIP1_HUMAN
θ value	9.29e-05 (rank : 76)	NC score	0.526250 (rank : 34)
Query Neighborhood Hits	474	Target Neighborhood Hits	231	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SNTG1_HUMAN
θ value	9.29e-05 (rank : 77)	NC score	0.456260 (rank : 69)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

GRIP1_MOUSE
θ value	0.000121331 (rank : 78)	NC score	0.523839 (rank : 42)
Query Neighborhood Hits	474	Target Neighborhood Hits	241	Shared Neighborhood Hits	174
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

TXND2_HUMAN
θ value	0.000121331 (rank : 79)	NC score	0.103433 (rank : 199)
Query Neighborhood Hits	474	Target Neighborhood Hits	793	Shared Neighborhood Hits	120
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MPP6_HUMAN
θ value	0.000158464 (rank : 80)	NC score	0.410960 (rank : 82)
Query Neighborhood Hits	474	Target Neighborhood Hits	180	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

PDZK4_MOUSE
θ value	0.000158464 (rank : 81)	NC score	0.399535 (rank : 89)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	124
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PARD3_HUMAN
θ value	0.000270298 (rank : 82)	NC score	0.507679 (rank : 50)
Query Neighborhood Hits	474	Target Neighborhood Hits	312	Shared Neighborhood Hits	156
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

USH1C_HUMAN
θ value	0.000270298 (rank : 83)	NC score	0.556683 (rank : 23)
Query Neighborhood Hits	474	Target Neighborhood Hits	327	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

NEB1_HUMAN
θ value	0.00035302 (rank : 84)	NC score	0.344689 (rank : 102)
Query Neighborhood Hits	474	Target Neighborhood Hits	829	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SNTB1_HUMAN
θ value	0.000461057 (rank : 85)	NC score	0.452236 (rank : 70)
Query Neighborhood Hits	474	Target Neighborhood Hits	157	Shared Neighborhood Hits	138
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	0.000461057 (rank : 86)	NC score	0.451467 (rank : 71)
Query Neighborhood Hits	474	Target Neighborhood Hits	160	Shared Neighborhood Hits	136
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PRAX_MOUSE
θ value	0.000602161 (rank : 87)	NC score	0.204927 (rank : 157)
Query Neighborhood Hits	474	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SNTB2_HUMAN
θ value	0.000602161 (rank : 88)	NC score	0.474886 (rank : 64)
Query Neighborhood Hits	474	Target Neighborhood Hits	180	Shared Neighborhood Hits	146
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	0.000602161 (rank : 89)	NC score	0.475885 (rank : 63)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	146
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

K1849_HUMAN
θ value	0.000786445 (rank : 90)	NC score	0.389016 (rank : 90)
Query Neighborhood Hits	474	Target Neighborhood Hits	220	Shared Neighborhood Hits	133
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PAR3L_HUMAN
θ value	0.000786445 (rank : 91)	NC score	0.521906 (rank : 44)
Query Neighborhood Hits	474	Target Neighborhood Hits	297	Shared Neighborhood Hits	155
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD1_HUMAN
θ value	0.000786445 (rank : 92)	NC score	0.480959 (rank : 62)
Query Neighborhood Hits	474	Target Neighborhood Hits	190	Shared Neighborhood Hits	146
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PRAX_HUMAN
θ value	0.000786445 (rank : 93)	NC score	0.181876 (rank : 166)
Query Neighborhood Hits	474	Target Neighborhood Hits	215	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

RPGF6_HUMAN
θ value	0.000786445 (rank : 94)	NC score	0.322153 (rank : 109)
Query Neighborhood Hits	474	Target Neighborhood Hits	266	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

GRIP2_HUMAN
θ value	0.00134147 (rank : 95)	NC score	0.534783 (rank : 31)
Query Neighborhood Hits	474	Target Neighborhood Hits	256	Shared Neighborhood Hits	174
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

ARHGC_HUMAN
θ value	0.00175202 (rank : 96)	NC score	0.244369 (rank : 134)
Query Neighborhood Hits	474	Target Neighborhood Hits	351	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

K1849_MOUSE
θ value	0.00175202 (rank : 97)	NC score	0.386041 (rank : 92)
Query Neighborhood Hits	474	Target Neighborhood Hits	335	Shared Neighborhood Hits	144
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PCLO_MOUSE
θ value	0.00175202 (rank : 98)	NC score	0.189754 (rank : 163)
Query Neighborhood Hits	474	Target Neighborhood Hits	2275	Shared Neighborhood Hits	291
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

IL16_MOUSE
θ value	0.00228821 (rank : 99)	NC score	0.496807 (rank : 56)
Query Neighborhood Hits	474	Target Neighborhood Hits	189	Shared Neighborhood Hits	137
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MPP6_MOUSE
θ value	0.00228821 (rank : 100)	NC score	0.403906 (rank : 83)
Query Neighborhood Hits	474	Target Neighborhood Hits	187	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

PARD3_MOUSE
θ value	0.00228821 (rank : 101)	NC score	0.502577 (rank : 52)
Query Neighborhood Hits	474	Target Neighborhood Hits	290	Shared Neighborhood Hits	156
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

NHERF_MOUSE
θ value	0.00298849 (rank : 102)	NC score	0.442592 (rank : 72)
Query Neighborhood Hits	474	Target Neighborhood Hits	195	Shared Neighborhood Hits	150
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD7_HUMAN
θ value	0.00298849 (rank : 103)	NC score	0.540120 (rank : 27)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

TARA_HUMAN
θ value	0.00298849 (rank : 104)	NC score	0.072644 (rank : 213)
Query Neighborhood Hits	474	Target Neighborhood Hits	1626	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ARHGC_MOUSE
θ value	0.00390308 (rank : 105)	NC score	0.239212 (rank : 137)
Query Neighborhood Hits	474	Target Neighborhood Hits	344	Shared Neighborhood Hits	142
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LIN7C_HUMAN
θ value	0.00390308 (rank : 106)	NC score	0.525102 (rank : 36)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.00390308 (rank : 107)	NC score	0.525102 (rank : 37)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	168
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

NFIB_HUMAN
θ value	0.00390308 (rank : 108)	NC score	0.050665 (rank : 277)
Query Neighborhood Hits	474	Target Neighborhood Hits	66	Shared Neighborhood Hits	17
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

TMM51_MOUSE
θ value	0.00390308 (rank : 109)	NC score	0.081880 (rank : 206)
Query Neighborhood Hits	474	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LG1, Q3TPZ3	Gene names	Tmem51
Domain Architecture	No domain graphic available
Description	Transmembrane protein 51.

TX1B3_HUMAN
θ value	0.00390308 (rank : 110)	NC score	0.527619 (rank : 33)
Query Neighborhood Hits	474	Target Neighborhood Hits	161	Shared Neighborhood Hits	144
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.00390308 (rank : 111)	NC score	0.524581 (rank : 39)
Query Neighborhood Hits	474	Target Neighborhood Hits	158	Shared Neighborhood Hits	141
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

GOPC_HUMAN
θ value	0.00509761 (rank : 112)	NC score	0.489740 (rank : 59)
Query Neighborhood Hits	474	Target Neighborhood Hits	377	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	0.00509761 (rank : 113)	NC score	0.498534 (rank : 54)
Query Neighborhood Hits	474	Target Neighborhood Hits	323	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LIMK2_MOUSE
θ value	0.00509761 (rank : 114)	NC score	0.032825 (rank : 333)
Query Neighborhood Hits	474	Target Neighborhood Hits	998	Shared Neighborhood Hits	75
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

NFIB_MOUSE
θ value	0.00509761 (rank : 115)	NC score	0.051099 (rank : 275)
Query Neighborhood Hits	474	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

SDCB2_MOUSE
θ value	0.00509761 (rank : 116)	NC score	0.301944 (rank : 113)
Query Neighborhood Hits	474	Target Neighborhood Hits	118	Shared Neighborhood Hits	104
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

ARHGB_HUMAN
θ value	0.00665767 (rank : 117)	NC score	0.252386 (rank : 129)
Query Neighborhood Hits	474	Target Neighborhood Hits	375	Shared Neighborhood Hits	159
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

DVL2_HUMAN
θ value	0.00665767 (rank : 118)	NC score	0.343647 (rank : 104)
Query Neighborhood Hits	474	Target Neighborhood Hits	223	Shared Neighborhood Hits	120
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0.00665767 (rank : 119)	NC score	0.344007 (rank : 103)
Query Neighborhood Hits	474	Target Neighborhood Hits	233	Shared Neighborhood Hits	124
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	0.00665767 (rank : 120)	NC score	0.359444 (rank : 96)
Query Neighborhood Hits	474	Target Neighborhood Hits	194	Shared Neighborhood Hits	116
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.00665767 (rank : 121)	NC score	0.360100 (rank : 95)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	117
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

RPGF2_HUMAN
θ value	0.00665767 (rank : 122)	NC score	0.279226 (rank : 121)
Query Neighborhood Hits	474	Target Neighborhood Hits	242	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

APBA3_MOUSE
θ value	0.00869519 (rank : 123)	NC score	0.295495 (rank : 117)
Query Neighborhood Hits	474	Target Neighborhood Hits	174	Shared Neighborhood Hits	120
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

LIMK2_HUMAN
θ value	0.00869519 (rank : 124)	NC score	0.030477 (rank : 351)
Query Neighborhood Hits	474	Target Neighborhood Hits	986	Shared Neighborhood Hits	78
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

SRRM1_MOUSE
θ value	0.00869519 (rank : 125)	NC score	0.103328 (rank : 200)
Query Neighborhood Hits	474	Target Neighborhood Hits	966	Shared Neighborhood Hits	137
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

K1914_MOUSE
θ value	0.0113563 (rank : 126)	NC score	0.050194 (rank : 280)
Query Neighborhood Hits	474	Target Neighborhood Hits	216	Shared Neighborhood Hits	28
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

LIN7B_HUMAN
θ value	0.0113563 (rank : 127)	NC score	0.524498 (rank : 40)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

MAP1A_HUMAN
θ value	0.0113563 (rank : 128)	NC score	0.056341 (rank : 261)
Query Neighborhood Hits	474	Target Neighborhood Hits	1626	Shared Neighborhood Hits	134
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYO15_MOUSE
θ value	0.0113563 (rank : 129)	NC score	0.022448 (rank : 395)
Query Neighborhood Hits	474	Target Neighborhood Hits	467	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ANK2_HUMAN
θ value	0.0148317 (rank : 130)	NC score	0.046289 (rank : 290)
Query Neighborhood Hits	474	Target Neighborhood Hits	1615	Shared Neighborhood Hits	156
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

LIN7B_MOUSE
θ value	0.0148317 (rank : 131)	NC score	0.522099 (rank : 43)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	170
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

SDCB1_HUMAN
θ value	0.0148317 (rank : 132)	NC score	0.354160 (rank : 99)
Query Neighborhood Hits	474	Target Neighborhood Hits	150	Shared Neighborhood Hits	131
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

ATX2L_HUMAN
θ value	0.0193708 (rank : 133)	NC score	0.070202 (rank : 216)
Query Neighborhood Hits	474	Target Neighborhood Hits	443	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

DVL1L_HUMAN
θ value	0.0193708 (rank : 134)	NC score	0.343511 (rank : 105)
Query Neighborhood Hits	474	Target Neighborhood Hits	146	Shared Neighborhood Hits	113
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	0.0193708 (rank : 135)	NC score	0.353952 (rank : 100)
Query Neighborhood Hits	474	Target Neighborhood Hits	158	Shared Neighborhood Hits	116
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	0.0193708 (rank : 136)	NC score	0.351089 (rank : 101)
Query Neighborhood Hits	474	Target Neighborhood Hits	146	Shared Neighborhood Hits	113
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SRRM1_HUMAN
θ value	0.0193708 (rank : 137)	NC score	0.108065 (rank : 195)
Query Neighborhood Hits	474	Target Neighborhood Hits	690	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ATX2L_MOUSE
θ value	0.0252991 (rank : 138)	NC score	0.060309 (rank : 252)
Query Neighborhood Hits	474	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

LIN7A_HUMAN
θ value	0.0252991 (rank : 139)	NC score	0.517041 (rank : 47)
Query Neighborhood Hits	474	Target Neighborhood Hits	193	Shared Neighborhood Hits	167
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.0252991 (rank : 140)	NC score	0.516898 (rank : 48)
Query Neighborhood Hits	474	Target Neighborhood Hits	193	Shared Neighborhood Hits	167
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

SDCB1_MOUSE
θ value	0.0252991 (rank : 141)	NC score	0.355952 (rank : 98)
Query Neighborhood Hits	474	Target Neighborhood Hits	144	Shared Neighborhood Hits	127
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

IWS1_HUMAN
θ value	0.0330416 (rank : 142)	NC score	0.065685 (rank : 229)
Query Neighborhood Hits	474	Target Neighborhood Hits	1241	Shared Neighborhood Hits	117
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NHRF2_HUMAN
θ value	0.0330416 (rank : 143)	NC score	0.419911 (rank : 79)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	159
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PDZD3_HUMAN
θ value	0.0330416 (rank : 144)	NC score	0.433979 (rank : 74)
Query Neighborhood Hits	474	Target Neighborhood Hits	180	Shared Neighborhood Hits	151
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

SYP2L_HUMAN
θ value	0.0330416 (rank : 145)	NC score	0.267331 (rank : 125)
Query Neighborhood Hits	474	Target Neighborhood Hits	400	Shared Neighborhood Hits	148
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

AKAP2_MOUSE
θ value	0.0431538 (rank : 146)	NC score	0.059828 (rank : 253)
Query Neighborhood Hits	474	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANK1_HUMAN
θ value	0.0431538 (rank : 147)	NC score	0.025879 (rank : 375)
Query Neighborhood Hits	474	Target Neighborhood Hits	416	Shared Neighborhood Hits	24
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ARI1A_HUMAN
θ value	0.0431538 (rank : 148)	NC score	0.075940 (rank : 210)
Query Neighborhood Hits	474	Target Neighborhood Hits	787	Shared Neighborhood Hits	114
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

RPB1_MOUSE
θ value	0.0431538 (rank : 149)	NC score	0.063088 (rank : 236)
Query Neighborhood Hits	474	Target Neighborhood Hits	363	Shared Neighborhood Hits	56
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

YLPM1_MOUSE
θ value	0.0431538 (rank : 150)	NC score	0.057400 (rank : 257)
Query Neighborhood Hits	474	Target Neighborhood Hits	505	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

GNDS_HUMAN
θ value	0.0563607 (rank : 151)	NC score	0.039304 (rank : 312)
Query Neighborhood Hits	474	Target Neighborhood Hits	201	Shared Neighborhood Hits	34
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

NHERF_HUMAN
θ value	0.0563607 (rank : 152)	NC score	0.419399 (rank : 80)
Query Neighborhood Hits	474	Target Neighborhood Hits	190	Shared Neighborhood Hits	150
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PRG4_HUMAN
θ value	0.0563607 (rank : 153)	NC score	0.068752 (rank : 222)
Query Neighborhood Hits	474	Target Neighborhood Hits	764	Shared Neighborhood Hits	109
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SYP2L_MOUSE
θ value	0.0563607 (rank : 154)	NC score	0.193236 (rank : 162)
Query Neighborhood Hits	474	Target Neighborhood Hits	289	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PEG3_MOUSE
θ value	0.0736092 (rank : 155)	NC score	0.006682 (rank : 486)
Query Neighborhood Hits	474	Target Neighborhood Hits	1101	Shared Neighborhood Hits	58
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RPB1_HUMAN
θ value	0.0736092 (rank : 156)	NC score	0.060931 (rank : 247)
Query Neighborhood Hits	474	Target Neighborhood Hits	362	Shared Neighborhood Hits	57
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ANK3_HUMAN
θ value	0.0961366 (rank : 157)	NC score	0.027750 (rank : 361)
Query Neighborhood Hits	474	Target Neighborhood Hits	853	Shared Neighborhood Hits	76
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

APBA3_HUMAN
θ value	0.0961366 (rank : 158)	NC score	0.278015 (rank : 122)
Query Neighborhood Hits	474	Target Neighborhood Hits	201	Shared Neighborhood Hits	128
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CSKP_MOUSE
θ value	0.0961366 (rank : 159)	NC score	0.130958 (rank : 188)
Query Neighborhood Hits	474	Target Neighborhood Hits	1027	Shared Neighborhood Hits	124
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

ETV5_MOUSE
θ value	0.0961366 (rank : 160)	NC score	0.032227 (rank : 339)
Query Neighborhood Hits	474	Target Neighborhood Hits	328	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

MPP4_MOUSE
θ value	0.0961366 (rank : 161)	NC score	0.383044 (rank : 93)
Query Neighborhood Hits	474	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

ZCPW1_MOUSE
θ value	0.0961366 (rank : 162)	NC score	0.060398 (rank : 251)
Query Neighborhood Hits	474	Target Neighborhood Hits	307	Shared Neighborhood Hits	39
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ANK1_MOUSE
θ value	0.125558 (rank : 163)	NC score	0.024491 (rank : 382)
Query Neighborhood Hits	474	Target Neighborhood Hits	430	Shared Neighborhood Hits	25
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

HTRA3_HUMAN
θ value	0.125558 (rank : 164)	NC score	0.097625 (rank : 201)
Query Neighborhood Hits	474	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

MPP3_HUMAN
θ value	0.125558 (rank : 165)	NC score	0.433392 (rank : 75)
Query Neighborhood Hits	474	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

NACAM_MOUSE
θ value	0.125558 (rank : 166)	NC score	0.085322 (rank : 204)
Query Neighborhood Hits	474	Target Neighborhood Hits	1866	Shared Neighborhood Hits	182
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RHPN1_MOUSE
θ value	0.125558 (rank : 167)	NC score	0.251054 (rank : 130)
Query Neighborhood Hits	474	Target Neighborhood Hits	154	Shared Neighborhood Hits	124
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

NPAS4_MOUSE
θ value	0.163984 (rank : 168)	NC score	0.051111 (rank : 274)
Query Neighborhood Hits	474	Target Neighborhood Hits	245	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PDLI3_MOUSE
θ value	0.163984 (rank : 169)	NC score	0.172309 (rank : 169)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	98
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI5_HUMAN
θ value	0.163984 (rank : 170)	NC score	0.145464 (rank : 181)
Query Neighborhood Hits	474	Target Neighborhood Hits	322	Shared Neighborhood Hits	116
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PICK1_HUMAN
θ value	0.163984 (rank : 171)	NC score	0.296386 (rank : 116)
Query Neighborhood Hits	474	Target Neighborhood Hits	132	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	0.163984 (rank : 172)	NC score	0.298540 (rank : 115)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	111
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PTN4_HUMAN
θ value	0.163984 (rank : 173)	NC score	0.127553 (rank : 189)
Query Neighborhood Hits	474	Target Neighborhood Hits	303	Shared Neighborhood Hits	125
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RBBP6_HUMAN
θ value	0.163984 (rank : 174)	NC score	0.065005 (rank : 231)
Query Neighborhood Hits	474	Target Neighborhood Hits	1135	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RIMS2_HUMAN
θ value	0.163984 (rank : 175)	NC score	0.167161 (rank : 174)
Query Neighborhood Hits	474	Target Neighborhood Hits	342	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.163984 (rank : 176)	NC score	0.166854 (rank : 175)
Query Neighborhood Hits	474	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

WASF3_HUMAN
θ value	0.163984 (rank : 177)	NC score	0.038446 (rank : 313)
Query Neighborhood Hits	474	Target Neighborhood Hits	204	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

YETS2_HUMAN
θ value	0.163984 (rank : 178)	NC score	0.033291 (rank : 330)
Query Neighborhood Hits	474	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BLNK_MOUSE
θ value	0.21417 (rank : 179)	NC score	0.063220 (rank : 235)
Query Neighborhood Hits	474	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

EFHB_MOUSE
θ value	0.21417 (rank : 180)	NC score	0.039499 (rank : 311)
Query Neighborhood Hits	474	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

TMM51_HUMAN
θ value	0.21417 (rank : 181)	NC score	0.056244 (rank : 262)
Query Neighborhood Hits	474	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NW97	Gene names	TMEM51, C1orf72
Domain Architecture	No domain graphic available
Description	Transmembrane protein 51.

WASIP_HUMAN
θ value	0.21417 (rank : 182)	NC score	0.063053 (rank : 237)
Query Neighborhood Hits	474	Target Neighborhood Hits	458	Shared Neighborhood Hits	76
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

AMOL1_MOUSE
θ value	0.279714 (rank : 183)	NC score	0.019910 (rank : 410)
Query Neighborhood Hits	474	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

HELZ_HUMAN
θ value	0.279714 (rank : 184)	NC score	0.024619 (rank : 381)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

LDB3_HUMAN
θ value	0.279714 (rank : 185)	NC score	0.145247 (rank : 182)
Query Neighborhood Hits	474	Target Neighborhood Hits	497	Shared Neighborhood Hits	135
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MDC1_MOUSE
θ value	0.279714 (rank : 186)	NC score	0.091335 (rank : 202)
Query Neighborhood Hits	474	Target Neighborhood Hits	998	Shared Neighborhood Hits	139
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC7_HUMAN
θ value	0.279714 (rank : 187)	NC score	0.088497 (rank : 203)
Query Neighborhood Hits	474	Target Neighborhood Hits	538	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PAIP1_HUMAN
θ value	0.279714 (rank : 188)	NC score	0.030842 (rank : 348)
Query Neighborhood Hits	474	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

PDLI2_HUMAN
θ value	0.279714 (rank : 189)	NC score	0.298721 (rank : 114)
Query Neighborhood Hits	474	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	0.279714 (rank : 190)	NC score	0.273339 (rank : 124)
Query Neighborhood Hits	474	Target Neighborhood Hits	220	Shared Neighborhood Hits	113
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

AAK1_HUMAN
θ value	0.365318 (rank : 191)	NC score	0.011351 (rank : 452)
Query Neighborhood Hits	474	Target Neighborhood Hits	1077	Shared Neighborhood Hits	92
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ASPP1_MOUSE
θ value	0.365318 (rank : 192)	NC score	0.045992 (rank : 292)
Query Neighborhood Hits	474	Target Neighborhood Hits	1244	Shared Neighborhood Hits	116
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CBP_MOUSE
θ value	0.365318 (rank : 193)	NC score	0.048921 (rank : 285)
Query Neighborhood Hits	474	Target Neighborhood Hits	1051	Shared Neighborhood Hits	135
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CJ078_MOUSE
θ value	0.365318 (rank : 194)	NC score	0.076784 (rank : 209)
Query Neighborhood Hits	474	Target Neighborhood Hits	559	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LCP2_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.059231 (rank : 255)
Query Neighborhood Hits	474	Target Neighborhood Hits	531	Shared Neighborhood Hits	100
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MPP3_MOUSE
θ value	0.365318 (rank : 196)	NC score	0.428741 (rank : 77)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

NBR1_HUMAN
θ value	0.365318 (rank : 197)	NC score	0.031084 (rank : 344)
Query Neighborhood Hits	474	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

PCLO_HUMAN
θ value	0.365318 (rank : 198)	NC score	0.069841 (rank : 217)
Query Neighborhood Hits	474	Target Neighborhood Hits	2046	Shared Neighborhood Hits	209
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PDLI5_MOUSE
θ value	0.365318 (rank : 199)	NC score	0.139162 (rank : 185)
Query Neighborhood Hits	474	Target Neighborhood Hits	287	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDZD3_MOUSE
θ value	0.365318 (rank : 200)	NC score	0.388570 (rank : 91)
Query Neighborhood Hits	474	Target Neighborhood Hits	171	Shared Neighborhood Hits	148
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

RBBP6_MOUSE
θ value	0.365318 (rank : 201)	NC score	0.060452 (rank : 250)
Query Neighborhood Hits	474	Target Neighborhood Hits	1014	Shared Neighborhood Hits	96
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RGS3_HUMAN
θ value	0.365318 (rank : 202)	NC score	0.075075 (rank : 211)
Query Neighborhood Hits	474	Target Neighborhood Hits	1375	Shared Neighborhood Hits	186
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TFG_HUMAN
θ value	0.365318 (rank : 203)	NC score	0.056454 (rank : 260)
Query Neighborhood Hits	474	Target Neighborhood Hits	122	Shared Neighborhood Hits	19
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

CSF1_MOUSE
θ value	0.47712 (rank : 204)	NC score	0.032039 (rank : 340)
Query Neighborhood Hits	474	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

GIDRP_MOUSE
θ value	0.47712 (rank : 205)	NC score	0.030871 (rank : 347)
Query Neighborhood Hits	474	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BJM3, Q3UGJ8, Q5U5U8	Gene names	Gidrp88, D19Ertd386e
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 homolog.

PDLI3_HUMAN
θ value	0.47712 (rank : 206)	NC score	0.185524 (rank : 165)
Query Neighborhood Hits	474	Target Neighborhood Hits	199	Shared Neighborhood Hits	101
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

HTRA3_MOUSE
θ value	0.62314 (rank : 207)	NC score	0.104988 (rank : 198)
Query Neighborhood Hits	474	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

IWS1_MOUSE
θ value	0.62314 (rank : 208)	NC score	0.062032 (rank : 242)
Query Neighborhood Hits	474	Target Neighborhood Hits	1258	Shared Neighborhood Hits	129
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MDC1_HUMAN
θ value	0.62314 (rank : 209)	NC score	0.078610 (rank : 208)
Query Neighborhood Hits	474	Target Neighborhood Hits	1446	Shared Neighborhood Hits	158
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NU214_HUMAN
θ value	0.62314 (rank : 210)	NC score	0.043997 (rank : 298)
Query Neighborhood Hits	474	Target Neighborhood Hits	657	Shared Neighborhood Hits	75
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PKHA2_HUMAN
θ value	0.62314 (rank : 211)	NC score	0.024684 (rank : 380)
Query Neighborhood Hits	474	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PSCBP_HUMAN
θ value	0.62314 (rank : 212)	NC score	0.209273 (rank : 154)
Query Neighborhood Hits	474	Target Neighborhood Hits	123	Shared Neighborhood Hits	105
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PTN23_MOUSE
θ value	0.62314 (rank : 213)	NC score	0.045518 (rank : 295)
Query Neighborhood Hits	474	Target Neighborhood Hits	726	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RERE_MOUSE
θ value	0.62314 (rank : 214)	NC score	0.049059 (rank : 284)
Query Neighborhood Hits	474	Target Neighborhood Hits	785	Shared Neighborhood Hits	107
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SDCB2_HUMAN
θ value	0.62314 (rank : 215)	NC score	0.280365 (rank : 119)
Query Neighborhood Hits	474	Target Neighborhood Hits	121	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SELPL_MOUSE
θ value	0.62314 (rank : 216)	NC score	0.057455 (rank : 256)
Query Neighborhood Hits	474	Target Neighborhood Hits	588	Shared Neighborhood Hits	93
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SFPQ_MOUSE
θ value	0.62314 (rank : 217)	NC score	0.031073 (rank : 345)
Query Neighborhood Hits	474	Target Neighborhood Hits	958	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

STXB4_HUMAN
θ value	0.62314 (rank : 218)	NC score	0.276300 (rank : 123)
Query Neighborhood Hits	474	Target Neighborhood Hits	616	Shared Neighborhood Hits	111
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TCOF_MOUSE
θ value	0.62314 (rank : 219)	NC score	0.062656 (rank : 238)
Query Neighborhood Hits	474	Target Neighborhood Hits	471	Shared Neighborhood Hits	75
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TJAP1_MOUSE
θ value	0.62314 (rank : 220)	NC score	0.032955 (rank : 332)
Query Neighborhood Hits	474	Target Neighborhood Hits	295	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

ZBT38_HUMAN
θ value	0.62314 (rank : 221)	NC score	-0.001231 (rank : 518)
Query Neighborhood Hits	474	Target Neighborhood Hits	885	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ZN217_HUMAN
θ value	0.62314 (rank : 222)	NC score	0.001211 (rank : 511)
Query Neighborhood Hits	474	Target Neighborhood Hits	905	Shared Neighborhood Hits	65
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

IDD_MOUSE
θ value	0.813845 (rank : 223)	NC score	0.031632 (rank : 343)
Query Neighborhood Hits	474	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

K0319_MOUSE
θ value	0.813845 (rank : 224)	NC score	0.026129 (rank : 372)
Query Neighborhood Hits	474	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LBXCO_HUMAN
θ value	0.813845 (rank : 225)	NC score	0.017657 (rank : 422)
Query Neighborhood Hits	474	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LCP2_MOUSE
θ value	0.813845 (rank : 226)	NC score	0.036232 (rank : 319)
Query Neighborhood Hits	474	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LTBP4_MOUSE
θ value	0.813845 (rank : 227)	NC score	0.002254 (rank : 507)
Query Neighborhood Hits	474	Target Neighborhood Hits	607	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MAST4_HUMAN
θ value	0.813845 (rank : 228)	NC score	0.050275 (rank : 279)
Query Neighborhood Hits	474	Target Neighborhood Hits	1804	Shared Neighborhood Hits	226
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MILK1_HUMAN
θ value	0.813845 (rank : 229)	NC score	0.041092 (rank : 305)
Query Neighborhood Hits	474	Target Neighborhood Hits	427	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NFH_HUMAN
θ value	0.813845 (rank : 230)	NC score	0.033358 (rank : 329)
Query Neighborhood Hits	474	Target Neighborhood Hits	1242	Shared Neighborhood Hits	113
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RANB3_MOUSE
θ value	0.813845 (rank : 231)	NC score	0.032562 (rank : 335)
Query Neighborhood Hits	474	Target Neighborhood Hits	123	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RBP2_MOUSE
θ value	0.813845 (rank : 232)	NC score	0.008633 (rank : 473)
Query Neighborhood Hits	474	Target Neighborhood Hits	232	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RC3H1_HUMAN
θ value	0.813845 (rank : 233)	NC score	0.033880 (rank : 327)
Query Neighborhood Hits	474	Target Neighborhood Hits	433	Shared Neighborhood Hits	55
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SH2D3_MOUSE
θ value	0.813845 (rank : 234)	NC score	0.014709 (rank : 438)
Query Neighborhood Hits	474	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

TGON2_HUMAN
θ value	0.813845 (rank : 235)	NC score	0.066547 (rank : 226)
Query Neighborhood Hits	474	Target Neighborhood Hits	1037	Shared Neighborhood Hits	123
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIAM1_HUMAN
θ value	0.813845 (rank : 236)	NC score	0.078703 (rank : 207)
Query Neighborhood Hits	474	Target Neighborhood Hits	225	Shared Neighborhood Hits	66
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	0.813845 (rank : 237)	NC score	0.061219 (rank : 245)
Query Neighborhood Hits	474	Target Neighborhood Hits	205	Shared Neighborhood Hits	48
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ZN509_MOUSE
θ value	0.813845 (rank : 238)	NC score	-0.004682 (rank : 524)
Query Neighborhood Hits	474	Target Neighborhood Hits	990	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

MLTK_MOUSE
θ value	1.06291 (rank : 239)	NC score	-0.001233 (rank : 519)
Query Neighborhood Hits	474	Target Neighborhood Hits	874	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

PDC6I_MOUSE
θ value	1.06291 (rank : 240)	NC score	0.030895 (rank : 346)
Query Neighborhood Hits	474	Target Neighborhood Hits	275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDLI7_HUMAN
θ value	1.06291 (rank : 241)	NC score	0.133877 (rank : 187)
Query Neighborhood Hits	474	Target Neighborhood Hits	547	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PKHA5_HUMAN
θ value	1.06291 (rank : 242)	NC score	0.034833 (rank : 322)
Query Neighborhood Hits	474	Target Neighborhood Hits	455	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SVIL_MOUSE
θ value	1.06291 (rank : 243)	NC score	0.045602 (rank : 294)
Query Neighborhood Hits	474	Target Neighborhood Hits	439	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

ZIM10_HUMAN
θ value	1.06291 (rank : 244)	NC score	0.027315 (rank : 366)
Query Neighborhood Hits	474	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ASPP1_HUMAN
θ value	1.38821 (rank : 245)	NC score	0.030503 (rank : 350)
Query Neighborhood Hits	474	Target Neighborhood Hits	956	Shared Neighborhood Hits	83
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASXL1_MOUSE
θ value	1.38821 (rank : 246)	NC score	0.027176 (rank : 367)
Query Neighborhood Hits	474	Target Neighborhood Hits	182	Shared Neighborhood Hits	35
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ATBF1_HUMAN
θ value	1.38821 (rank : 247)	NC score	0.015141 (rank : 431)
Query Neighborhood Hits	474	Target Neighborhood Hits	1547	Shared Neighborhood Hits	99
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

AUTS2_HUMAN
θ value	1.38821 (rank : 248)	NC score	0.045614 (rank : 293)
Query Neighborhood Hits	474	Target Neighborhood Hits	342	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

EGR2_MOUSE
θ value	1.38821 (rank : 249)	NC score	-0.004707 (rank : 525)
Query Neighborhood Hits	474	Target Neighborhood Hits	745	Shared Neighborhood Hits	23
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

FOXM1_MOUSE
θ value	1.38821 (rank : 250)	NC score	0.009677 (rank : 463)
Query Neighborhood Hits	474	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	O08696	Gene names	Foxm1, Fkh16
Domain Architecture
Description	Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).

GAK2_HUMAN
θ value	1.38821 (rank : 251)	NC score	0.027986 (rank : 358)
Query Neighborhood Hits	474	Target Neighborhood Hits	406	Shared Neighborhood Hits	60
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HTRA1_HUMAN
θ value	1.38821 (rank : 252)	NC score	0.063727 (rank : 233)
Query Neighborhood Hits	474	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HXA3_HUMAN
θ value	1.38821 (rank : 253)	NC score	0.005733 (rank : 490)
Query Neighborhood Hits	474	Target Neighborhood Hits	535	Shared Neighborhood Hits	47
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

LDB3_MOUSE
θ value	1.38821 (rank : 254)	NC score	0.147596 (rank : 180)
Query Neighborhood Hits	474	Target Neighborhood Hits	510	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LR37A_HUMAN
θ value	1.38821 (rank : 255)	NC score	0.040523 (rank : 307)
Query Neighborhood Hits	474	Target Neighborhood Hits	720	Shared Neighborhood Hits	97
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

M4K4_MOUSE
θ value	1.38821 (rank : 256)	NC score	0.004563 (rank : 495)
Query Neighborhood Hits	474	Target Neighborhood Hits	1560	Shared Neighborhood Hits	66
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MPP4_HUMAN
θ value	1.38821 (rank : 257)	NC score	0.401494 (rank : 87)
Query Neighborhood Hits	474	Target Neighborhood Hits	205	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MTG8_HUMAN
θ value	1.38821 (rank : 258)	NC score	0.017556 (rank : 423)
Query Neighborhood Hits	474	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

MTG8_MOUSE
θ value	1.38821 (rank : 259)	NC score	0.017840 (rank : 421)
Query Neighborhood Hits	474	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

MUC2_HUMAN
θ value	1.38821 (rank : 260)	NC score	0.035606 (rank : 321)
Query Neighborhood Hits	474	Target Neighborhood Hits	906	Shared Neighborhood Hits	84
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NEO1_HUMAN
θ value	1.38821 (rank : 261)	NC score	0.016016 (rank : 429)
Query Neighborhood Hits	474	Target Neighborhood Hits	530	Shared Neighborhood Hits	25
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NUFP1_MOUSE
θ value	1.38821 (rank : 262)	NC score	0.019550 (rank : 411)
Query Neighborhood Hits	474	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

S18L1_HUMAN
θ value	1.38821 (rank : 263)	NC score	0.021287 (rank : 402)
Query Neighborhood Hits	474	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	O75177, Q5JXJ3, Q8NE69, Q9BR55, Q9H4K6	Gene names	SS18L1, KIAA0693
Domain Architecture
Description	SS18-like protein 1 (SYT homolog 1).

SHD_HUMAN
θ value	1.38821 (rank : 264)	NC score	0.015001 (rank : 434)
Query Neighborhood Hits	474	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

TOPB1_MOUSE
θ value	1.38821 (rank : 265)	NC score	0.015059 (rank : 432)
Query Neighborhood Hits	474	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

TREF1_HUMAN
θ value	1.38821 (rank : 266)	NC score	0.016284 (rank : 427)
Query Neighborhood Hits	474	Target Neighborhood Hits	651	Shared Neighborhood Hits	44
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

AFAD_HUMAN
θ value	1.81305 (rank : 267)	NC score	0.338887 (rank : 107)
Query Neighborhood Hits	474	Target Neighborhood Hits	689	Shared Neighborhood Hits	166
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

B4GN4_HUMAN
θ value	1.81305 (rank : 268)	NC score	0.015547 (rank : 430)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	27
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BCL6_HUMAN
θ value	1.81305 (rank : 269)	NC score	-0.004673 (rank : 523)
Query Neighborhood Hits	474	Target Neighborhood Hits	922	Shared Neighborhood Hits	40
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

CBP_HUMAN
θ value	1.81305 (rank : 270)	NC score	0.049163 (rank : 283)
Query Neighborhood Hits	474	Target Neighborhood Hits	941	Shared Neighborhood Hits	115
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CTND2_MOUSE
θ value	1.81305 (rank : 271)	NC score	0.012538 (rank : 447)
Query Neighborhood Hits	474	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

GAK12_HUMAN
θ value	1.81305 (rank : 272)	NC score	0.026912 (rank : 370)
Query Neighborhood Hits	474	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HIPK1_MOUSE
θ value	1.81305 (rank : 273)	NC score	0.002493 (rank : 504)
Query Neighborhood Hits	474	Target Neighborhood Hits	838	Shared Neighborhood Hits	33
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

HTRA1_MOUSE
θ value	1.81305 (rank : 274)	NC score	0.062366 (rank : 239)
Query Neighborhood Hits	474	Target Neighborhood Hits	140	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

M3K9_HUMAN
θ value	1.81305 (rank : 275)	NC score	0.000374 (rank : 515)
Query Neighborhood Hits	474	Target Neighborhood Hits	1123	Shared Neighborhood Hits	57
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MAST2_MOUSE
θ value	1.81305 (rank : 276)	NC score	0.038061 (rank : 314)
Query Neighborhood Hits	474	Target Neighborhood Hits	1110	Shared Neighborhood Hits	148
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MYPN_MOUSE
θ value	1.81305 (rank : 277)	NC score	0.028500 (rank : 355)
Query Neighborhood Hits	474	Target Neighborhood Hits	421	Shared Neighborhood Hits	36
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NCOA6_HUMAN
θ value	1.81305 (rank : 278)	NC score	0.055331 (rank : 264)
Query Neighborhood Hits	474	Target Neighborhood Hits	1202	Shared Neighborhood Hits	155
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOR1_MOUSE
θ value	1.81305 (rank : 279)	NC score	0.033950 (rank : 326)
Query Neighborhood Hits	474	Target Neighborhood Hits	521	Shared Neighborhood Hits	75
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NHRF2_MOUSE
θ value	1.81305 (rank : 280)	NC score	0.402736 (rank : 86)
Query Neighborhood Hits	474	Target Neighborhood Hits	194	Shared Neighborhood Hits	161
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NOS1_HUMAN
θ value	1.81305 (rank : 281)	NC score	0.215674 (rank : 150)
Query Neighborhood Hits	474	Target Neighborhood Hits	218	Shared Neighborhood Hits	133
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDLI1_HUMAN
θ value	1.81305 (rank : 282)	NC score	0.154391 (rank : 177)
Query Neighborhood Hits	474	Target Neighborhood Hits	242	Shared Neighborhood Hits	92
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_MOUSE
θ value	1.81305 (rank : 283)	NC score	0.187446 (rank : 164)
Query Neighborhood Hits	474	Target Neighborhood Hits	233	Shared Neighborhood Hits	104
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDZD8_HUMAN
θ value	1.81305 (rank : 284)	NC score	0.117505 (rank : 192)
Query Neighborhood Hits	474	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PHAR2_HUMAN
θ value	1.81305 (rank : 285)	NC score	0.033109 (rank : 331)
Query Neighborhood Hits	474	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

REXO1_MOUSE
θ value	1.81305 (rank : 286)	NC score	0.021923 (rank : 398)
Query Neighborhood Hits	474	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RGS3_MOUSE
θ value	1.81305 (rank : 287)	NC score	0.084794 (rank : 205)
Query Neighborhood Hits	474	Target Neighborhood Hits	1621	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN1_HUMAN
θ value	1.81305 (rank : 288)	NC score	0.229299 (rank : 141)
Query Neighborhood Hits	474	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

STAT6_MOUSE
θ value	1.81305 (rank : 289)	NC score	0.014854 (rank : 437)
Query Neighborhood Hits	474	Target Neighborhood Hits	78	Shared Neighborhood Hits	16
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

WDR46_MOUSE
θ value	1.81305 (rank : 290)	NC score	0.023017 (rank : 391)
Query Neighborhood Hits	474	Target Neighborhood Hits	243	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZIM10_MOUSE
θ value	1.81305 (rank : 291)	NC score	0.025052 (rank : 379)
Query Neighborhood Hits	474	Target Neighborhood Hits	430	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

5NT1B_MOUSE
θ value	2.36792 (rank : 292)	NC score	0.020185 (rank : 409)
Query Neighborhood Hits	474	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

AMPN_MOUSE
θ value	2.36792 (rank : 293)	NC score	0.005688 (rank : 491)
Query Neighborhood Hits	474	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P97449, Q91YH8, Q99K63	Gene names	Anpep, Lap-1, Lap1
Domain Architecture
Description	Aminopeptidase N (EC 3.4.11.2) (mAPN) (Alanyl aminopeptidase) (Microsomal aminopeptidase) (Aminopeptidase M) (Membrane protein p161) (CD13 antigen).

APBA1_HUMAN
θ value	2.36792 (rank : 294)	NC score	0.304658 (rank : 112)
Query Neighborhood Hits	474	Target Neighborhood Hits	325	Shared Neighborhood Hits	147
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CNTRB_MOUSE
θ value	2.36792 (rank : 295)	NC score	0.019005 (rank : 415)
Query Neighborhood Hits	474	Target Neighborhood Hits	1029	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

FRM4B_MOUSE
θ value	2.36792 (rank : 296)	NC score	0.023395 (rank : 388)
Query Neighborhood Hits	474	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

HGS_MOUSE
θ value	2.36792 (rank : 297)	NC score	0.022996 (rank : 392)
Query Neighborhood Hits	474	Target Neighborhood Hits	589	Shared Neighborhood Hits	72
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HNRL1_MOUSE
θ value	2.36792 (rank : 298)	NC score	0.034043 (rank : 325)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

KI67_HUMAN
θ value	2.36792 (rank : 299)	NC score	0.049605 (rank : 282)
Query Neighborhood Hits	474	Target Neighborhood Hits	581	Shared Neighborhood Hits	82
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LOXL1_MOUSE
θ value	2.36792 (rank : 300)	NC score	0.011464 (rank : 451)
Query Neighborhood Hits	474	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

LRC8E_MOUSE
θ value	2.36792 (rank : 301)	NC score	0.031732 (rank : 342)
Query Neighborhood Hits	474	Target Neighborhood Hits	256	Shared Neighborhood Hits	10
SwissProt Accessions	Q66JT1	Gene names	Lrrc8e
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

MEF2A_HUMAN
θ value	2.36792 (rank : 302)	NC score	0.009973 (rank : 462)
Query Neighborhood Hits	474	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

MMP15_MOUSE
θ value	2.36792 (rank : 303)	NC score	0.003721 (rank : 498)
Query Neighborhood Hits	474	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MYPN_HUMAN
θ value	2.36792 (rank : 304)	NC score	0.025381 (rank : 377)
Query Neighborhood Hits	474	Target Neighborhood Hits	418	Shared Neighborhood Hits	42
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

NEO1_MOUSE
θ value	2.36792 (rank : 305)	NC score	0.016154 (rank : 428)
Query Neighborhood Hits	474	Target Neighborhood Hits	523	Shared Neighborhood Hits	24
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

PAK6_HUMAN
θ value	2.36792 (rank : 306)	NC score	0.000517 (rank : 514)
Query Neighborhood Hits	474	Target Neighborhood Hits	915	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

RNC_HUMAN
θ value	2.36792 (rank : 307)	NC score	0.027805 (rank : 360)
Query Neighborhood Hits	474	Target Neighborhood Hits	176	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

SRC8_MOUSE
θ value	2.36792 (rank : 308)	NC score	0.014918 (rank : 436)
Query Neighborhood Hits	474	Target Neighborhood Hits	292	Shared Neighborhood Hits	25
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SVIL_HUMAN
θ value	2.36792 (rank : 309)	NC score	0.032409 (rank : 337)
Query Neighborhood Hits	474	Target Neighborhood Hits	232	Shared Neighborhood Hits	41
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SYN3_MOUSE
θ value	2.36792 (rank : 310)	NC score	0.028658 (rank : 354)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

TF7L1_HUMAN
θ value	2.36792 (rank : 311)	NC score	0.010728 (rank : 458)
Query Neighborhood Hits	474	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
θ value	2.36792 (rank : 312)	NC score	0.011733 (rank : 448)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

WWP2_HUMAN
θ value	2.36792 (rank : 313)	NC score	0.028209 (rank : 357)
Query Neighborhood Hits	474	Target Neighborhood Hits	177	Shared Neighborhood Hits	33
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

BSPRY_MOUSE
θ value	3.0926 (rank : 314)	NC score	0.007998 (rank : 477)
Query Neighborhood Hits	474	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

CBL_HUMAN
θ value	3.0926 (rank : 315)	NC score	0.020619 (rank : 407)
Query Neighborhood Hits	474	Target Neighborhood Hits	353	Shared Neighborhood Hits	42
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CDC73_HUMAN
θ value	3.0926 (rank : 316)	NC score	0.021724 (rank : 399)
Query Neighborhood Hits	474	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P1J9, Q6PK51, Q96A07, Q9H245, Q9H5L7	Gene names	CDC73, C1orf28, HRPT2
Domain Architecture	No domain graphic available
Description	Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein).

CDC73_MOUSE
θ value	3.0926 (rank : 317)	NC score	0.021724 (rank : 400)
Query Neighborhood Hits	474	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q8JZM7	Gene names	Cdc73
Domain Architecture	No domain graphic available
Description	Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein homolog).

CHD8_HUMAN
θ value	3.0926 (rank : 318)	NC score	0.007311 (rank : 481)
Query Neighborhood Hits	474	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

FA13C_HUMAN
θ value	3.0926 (rank : 319)	NC score	0.016831 (rank : 425)
Query Neighborhood Hits	474	Target Neighborhood Hits	94	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FOXN4_MOUSE
θ value	3.0926 (rank : 320)	NC score	0.004398 (rank : 497)
Query Neighborhood Hits	474	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

GAK5_HUMAN
θ value	3.0926 (rank : 321)	NC score	0.027088 (rank : 368)
Query Neighborhood Hits	474	Target Neighborhood Hits	429	Shared Neighborhood Hits	69
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAS1_HUMAN
θ value	3.0926 (rank : 322)	NC score	0.026455 (rank : 371)
Query Neighborhood Hits	474	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

HIPK1_HUMAN
θ value	3.0926 (rank : 323)	NC score	0.002343 (rank : 506)
Query Neighborhood Hits	474	Target Neighborhood Hits	843	Shared Neighborhood Hits	34
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

ICB1_MOUSE
θ value	3.0926 (rank : 324)	NC score	0.020682 (rank : 406)
Query Neighborhood Hits	474	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

LAD1_HUMAN
θ value	3.0926 (rank : 325)	NC score	0.047564 (rank : 288)
Query Neighborhood Hits	474	Target Neighborhood Hits	441	Shared Neighborhood Hits	79
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LMO7_HUMAN
θ value	3.0926 (rank : 326)	NC score	0.122309 (rank : 191)
Query Neighborhood Hits	474	Target Neighborhood Hits	507	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MLL3_MOUSE
θ value	3.0926 (rank : 327)	NC score	0.037447 (rank : 317)
Query Neighborhood Hits	474	Target Neighborhood Hits	1399	Shared Neighborhood Hits	130
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PML_HUMAN
θ value	3.0926 (rank : 328)	NC score	0.012842 (rank : 445)
Query Neighborhood Hits	474	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PRGC1_MOUSE
θ value	3.0926 (rank : 329)	NC score	0.018832 (rank : 416)
Query Neighborhood Hits	474	Target Neighborhood Hits	238	Shared Neighborhood Hits	30
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

RCOR2_HUMAN
θ value	3.0926 (rank : 330)	NC score	0.016420 (rank : 426)
Query Neighborhood Hits	474	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

SAPS1_HUMAN
θ value	3.0926 (rank : 331)	NC score	0.032467 (rank : 336)
Query Neighborhood Hits	474	Target Neighborhood Hits	704	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SIM2_MOUSE
θ value	3.0926 (rank : 332)	NC score	0.006296 (rank : 488)
Query Neighborhood Hits	474	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SRBS1_MOUSE
θ value	3.0926 (rank : 333)	NC score	0.020467 (rank : 408)
Query Neighborhood Hits	474	Target Neighborhood Hits	409	Shared Neighborhood Hits	58
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	3.0926 (rank : 334)	NC score	0.015029 (rank : 433)
Query Neighborhood Hits	474	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

TP53B_MOUSE
θ value	3.0926 (rank : 335)	NC score	0.041681 (rank : 304)
Query Neighborhood Hits	474	Target Neighborhood Hits	644	Shared Neighborhood Hits	91
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

US6NL_HUMAN
θ value	3.0926 (rank : 336)	NC score	0.026127 (rank : 373)
Query Neighborhood Hits	474	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

WASF3_MOUSE
θ value	3.0926 (rank : 337)	NC score	0.028353 (rank : 356)
Query Neighborhood Hits	474	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

APBA2_HUMAN
θ value	4.03905 (rank : 338)	NC score	0.281201 (rank : 118)
Query Neighborhood Hits	474	Target Neighborhood Hits	220	Shared Neighborhood Hits	148
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	4.03905 (rank : 339)	NC score	0.279741 (rank : 120)
Query Neighborhood Hits	474	Target Neighborhood Hits	219	Shared Neighborhood Hits	140
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APC_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.027478 (rank : 364)
Query Neighborhood Hits	474	Target Neighborhood Hits	441	Shared Neighborhood Hits	52
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

BAZ2A_HUMAN
θ value	4.03905 (rank : 341)	NC score	0.022791 (rank : 393)
Query Neighborhood Hits	474	Target Neighborhood Hits	780	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BLNK_HUMAN
θ value	4.03905 (rank : 342)	NC score	0.042744 (rank : 300)
Query Neighborhood Hits	474	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BRD4_MOUSE
θ value	4.03905 (rank : 343)	NC score	0.037961 (rank : 315)
Query Neighborhood Hits	474	Target Neighborhood Hits	845	Shared Neighborhood Hits	112
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CAC1B_MOUSE
θ value	4.03905 (rank : 344)	NC score	0.006814 (rank : 483)
Query Neighborhood Hits	474	Target Neighborhood Hits	351	Shared Neighborhood Hits	35
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CD6_MOUSE
θ value	4.03905 (rank : 345)	NC score	0.005514 (rank : 492)
Query Neighborhood Hits	474	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

CING_HUMAN
θ value	4.03905 (rank : 346)	NC score	0.010690 (rank : 459)
Query Neighborhood Hits	474	Target Neighborhood Hits	1275	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

ENL_HUMAN
θ value	4.03905 (rank : 347)	NC score	0.047176 (rank : 289)
Query Neighborhood Hits	474	Target Neighborhood Hits	305	Shared Neighborhood Hits	54
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ETV5_HUMAN
θ value	4.03905 (rank : 348)	NC score	0.013952 (rank : 440)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	33
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

GAK10_HUMAN
θ value	4.03905 (rank : 349)	NC score	0.023369 (rank : 389)
Query Neighborhood Hits	474	Target Neighborhood Hits	289	Shared Neighborhood Hits	51
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK8_HUMAN
θ value	4.03905 (rank : 350)	NC score	0.018346 (rank : 418)
Query Neighborhood Hits	474	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GGN_MOUSE
θ value	4.03905 (rank : 351)	NC score	0.034812 (rank : 323)
Query Neighborhood Hits	474	Target Neighborhood Hits	311	Shared Neighborhood Hits	49
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GP124_HUMAN
θ value	4.03905 (rank : 352)	NC score	0.003024 (rank : 500)
Query Neighborhood Hits	474	Target Neighborhood Hits	304	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

HNRL1_HUMAN
θ value	4.03905 (rank : 353)	NC score	0.026069 (rank : 374)
Query Neighborhood Hits	474	Target Neighborhood Hits	173	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

IF4B_HUMAN
θ value	4.03905 (rank : 354)	NC score	0.022579 (rank : 394)
Query Neighborhood Hits	474	Target Neighborhood Hits	417	Shared Neighborhood Hits	50
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

JAD1C_HUMAN
θ value	4.03905 (rank : 355)	NC score	0.009412 (rank : 464)
Query Neighborhood Hits	474	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

K1024_HUMAN
θ value	4.03905 (rank : 356)	NC score	0.010957 (rank : 457)
Query Neighborhood Hits	474	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

MAST1_MOUSE
θ value	4.03905 (rank : 357)	NC score	0.033395 (rank : 328)
Query Neighborhood Hits	474	Target Neighborhood Hits	1123	Shared Neighborhood Hits	138
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
θ value	4.03905 (rank : 358)	NC score	0.039723 (rank : 310)
Query Neighborhood Hits	474	Target Neighborhood Hits	1189	Shared Neighborhood Hits	155
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MBP_MOUSE
θ value	4.03905 (rank : 359)	NC score	0.014155 (rank : 439)
Query Neighborhood Hits	474	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P04370, Q01585, Q03139, Q03176, Q61836, Q61837, Q99KE4, Q9QWP1	Gene names	Mbp, Shi
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein).

MUCDL_MOUSE
θ value	4.03905 (rank : 360)	NC score	0.027927 (rank : 359)
Query Neighborhood Hits	474	Target Neighborhood Hits	461	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYST3_HUMAN
θ value	4.03905 (rank : 361)	NC score	0.023863 (rank : 383)
Query Neighborhood Hits	474	Target Neighborhood Hits	772	Shared Neighborhood Hits	76
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

OGFR_MOUSE
θ value	4.03905 (rank : 362)	NC score	0.045045 (rank : 297)
Query Neighborhood Hits	474	Target Neighborhood Hits	584	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PAR6B_HUMAN
θ value	4.03905 (rank : 363)	NC score	0.256925 (rank : 128)
Query Neighborhood Hits	474	Target Neighborhood Hits	126	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	4.03905 (rank : 364)	NC score	0.258396 (rank : 127)
Query Neighborhood Hits	474	Target Neighborhood Hits	128	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

RBP56_HUMAN
θ value	4.03905 (rank : 365)	NC score	0.013711 (rank : 442)
Query Neighborhood Hits	474	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q92804, Q92751	Gene names	TAF15, RBP56, TAF2N
Domain Architecture
Description	TATA-binding protein-associated factor 2N (RNA-binding protein 56) (TAFII68) (TAF(II)68).

RGS12_HUMAN
θ value	4.03905 (rank : 366)	NC score	0.201804 (rank : 159)
Query Neighborhood Hits	474	Target Neighborhood Hits	333	Shared Neighborhood Hits	134
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SET1A_HUMAN
θ value	4.03905 (rank : 367)	NC score	0.050112 (rank : 281)
Query Neighborhood Hits	474	Target Neighborhood Hits	690	Shared Neighborhood Hits	104
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFRIP_HUMAN
θ value	4.03905 (rank : 368)	NC score	0.042459 (rank : 302)
Query Neighborhood Hits	474	Target Neighborhood Hits	530	Shared Neighborhood Hits	73
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SPA3A_MOUSE
θ value	4.03905 (rank : 369)	NC score	-0.000386 (rank : 517)
Query Neighborhood Hits	474	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P4P1, Q9D490	Gene names	Serpina3a
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3A precursor (Serpin A3A).

TACC3_MOUSE
θ value	4.03905 (rank : 370)	NC score	0.011234 (rank : 453)
Query Neighborhood Hits	474	Target Neighborhood Hits	607	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TFE2_MOUSE
θ value	4.03905 (rank : 371)	NC score	0.008211 (rank : 476)
Query Neighborhood Hits	474	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

UBP8_HUMAN
θ value	4.03905 (rank : 372)	NC score	0.006771 (rank : 485)
Query Neighborhood Hits	474	Target Neighborhood Hits	751	Shared Neighborhood Hits	52
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ZAN_HUMAN
θ value	4.03905 (rank : 373)	NC score	0.022247 (rank : 396)
Query Neighborhood Hits	474	Target Neighborhood Hits	679	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

AIM1_HUMAN
θ value	5.27518 (rank : 374)	NC score	0.018775 (rank : 417)
Query Neighborhood Hits	474	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

BSN_MOUSE
θ value	5.27518 (rank : 375)	NC score	0.055203 (rank : 266)
Query Neighborhood Hits	474	Target Neighborhood Hits	2057	Shared Neighborhood Hits	199
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CD2AP_HUMAN
θ value	5.27518 (rank : 376)	NC score	0.023548 (rank : 385)
Query Neighborhood Hits	474	Target Neighborhood Hits	315	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CN155_HUMAN
θ value	5.27518 (rank : 377)	NC score	0.048813 (rank : 286)
Query Neighborhood Hits	474	Target Neighborhood Hits	385	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

ENAM_MOUSE
θ value	5.27518 (rank : 378)	NC score	0.030660 (rank : 349)
Query Neighborhood Hits	474	Target Neighborhood Hits	229	Shared Neighborhood Hits	55
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

EP300_HUMAN
θ value	5.27518 (rank : 379)	NC score	0.046190 (rank : 291)
Query Neighborhood Hits	474	Target Neighborhood Hits	821	Shared Neighborhood Hits	116
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FILA_HUMAN
θ value	5.27518 (rank : 380)	NC score	0.025082 (rank : 378)
Query Neighborhood Hits	474	Target Neighborhood Hits	685	Shared Neighborhood Hits	55
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FRK_HUMAN
θ value	5.27518 (rank : 381)	NC score	0.011146 (rank : 455)
Query Neighborhood Hits	474	Target Neighborhood Hits	1058	Shared Neighborhood Hits	59
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

GAK1_HUMAN
θ value	5.27518 (rank : 382)	NC score	0.021662 (rank : 401)
Query Neighborhood Hits	474	Target Neighborhood Hits	268	Shared Neighborhood Hits	46
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP124_MOUSE
θ value	5.27518 (rank : 383)	NC score	0.002983 (rank : 502)
Query Neighborhood Hits	474	Target Neighborhood Hits	423	Shared Neighborhood Hits	18
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

HGS_HUMAN
θ value	5.27518 (rank : 384)	NC score	0.019533 (rank : 412)
Query Neighborhood Hits	474	Target Neighborhood Hits	517	Shared Neighborhood Hits	60
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HXC4_MOUSE
θ value	5.27518 (rank : 385)	NC score	-0.001442 (rank : 520)
Query Neighborhood Hits	474	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

JAD1C_MOUSE
θ value	5.27518 (rank : 386)	NC score	0.008681 (rank : 472)
Query Neighborhood Hits	474	Target Neighborhood Hits	164	Shared Neighborhood Hits	13
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

MAST1_HUMAN
θ value	5.27518 (rank : 387)	NC score	0.032610 (rank : 334)
Query Neighborhood Hits	474	Target Neighborhood Hits	1146	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MINT_HUMAN
θ value	5.27518 (rank : 388)	NC score	0.036227 (rank : 320)
Query Neighborhood Hits	474	Target Neighborhood Hits	1291	Shared Neighborhood Hits	136
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST3_MOUSE
θ value	5.27518 (rank : 389)	NC score	0.023618 (rank : 384)
Query Neighborhood Hits	474	Target Neighborhood Hits	688	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NFH_MOUSE
θ value	5.27518 (rank : 390)	NC score	0.053710 (rank : 268)
Query Neighborhood Hits	474	Target Neighborhood Hits	2247	Shared Neighborhood Hits	191
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHLA1_MOUSE
θ value	5.27518 (rank : 391)	NC score	0.019027 (rank : 414)
Query Neighborhood Hits	474	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

PRDM8_HUMAN
θ value	5.27518 (rank : 392)	NC score	0.006809 (rank : 484)
Query Neighborhood Hits	474	Target Neighborhood Hits	591	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQV8, Q6IQ36	Gene names	PRDM8, PFM5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

PTN3_HUMAN
θ value	5.27518 (rank : 393)	NC score	0.112273 (rank : 194)
Query Neighborhood Hits	474	Target Neighborhood Hits	258	Shared Neighborhood Hits	114
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RAI14_MOUSE
θ value	5.27518 (rank : 394)	NC score	0.013782 (rank : 441)
Query Neighborhood Hits	474	Target Neighborhood Hits	1505	Shared Neighborhood Hits	74
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RERE_HUMAN
θ value	5.27518 (rank : 395)	NC score	0.042727 (rank : 301)
Query Neighborhood Hits	474	Target Neighborhood Hits	779	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RP1L1_MOUSE
θ value	5.27518 (rank : 396)	NC score	0.011232 (rank : 454)
Query Neighborhood Hits	474	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SACS_HUMAN
θ value	5.27518 (rank : 397)	NC score	0.007633 (rank : 480)
Query Neighborhood Hits	474	Target Neighborhood Hits	128	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

SMAD5_MOUSE
θ value	5.27518 (rank : 398)	NC score	0.004708 (rank : 494)
Query Neighborhood Hits	474	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMCA2_HUMAN
θ value	5.27518 (rank : 399)	NC score	0.008916 (rank : 470)
Query Neighborhood Hits	474	Target Neighborhood Hits	503	Shared Neighborhood Hits	45
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SPEG_MOUSE
θ value	5.27518 (rank : 400)	NC score	0.018127 (rank : 420)
Query Neighborhood Hits	474	Target Neighborhood Hits	1959	Shared Neighborhood Hits	163
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPTA3_MOUSE
θ value	5.27518 (rank : 401)	NC score	0.042238 (rank : 303)
Query Neighborhood Hits	474	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

SRGP2_HUMAN
θ value	5.27518 (rank : 402)	NC score	0.008898 (rank : 471)
Query Neighborhood Hits	474	Target Neighborhood Hits	331	Shared Neighborhood Hits	27
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SSXT_HUMAN
θ value	5.27518 (rank : 403)	NC score	0.025414 (rank : 376)
Query Neighborhood Hits	474	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

STXB4_MOUSE
θ value	5.27518 (rank : 404)	NC score	0.262444 (rank : 126)
Query Neighborhood Hits	474	Target Neighborhood Hits	629	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYN2_MOUSE
θ value	5.27518 (rank : 405)	NC score	0.021266 (rank : 403)
Query Neighborhood Hits	474	Target Neighborhood Hits	183	Shared Neighborhood Hits	44
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SYN3_HUMAN
θ value	5.27518 (rank : 406)	NC score	0.023435 (rank : 386)
Query Neighborhood Hits	474	Target Neighborhood Hits	203	Shared Neighborhood Hits	47
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TBX3_MOUSE
θ value	5.27518 (rank : 407)	NC score	0.002226 (rank : 508)
Query Neighborhood Hits	474	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TEX2_HUMAN
θ value	5.27518 (rank : 408)	NC score	0.018301 (rank : 419)
Query Neighborhood Hits	474	Target Neighborhood Hits	106	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TEX2_MOUSE
θ value	5.27518 (rank : 409)	NC score	0.021069 (rank : 405)
Query Neighborhood Hits	474	Target Neighborhood Hits	121	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TF2L1_HUMAN
θ value	5.27518 (rank : 410)	NC score	0.011122 (rank : 456)
Query Neighborhood Hits	474	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZI6, Q4ZG43	Gene names	TFCP2L1, CRTR1, LBP9
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9).

TF2L1_MOUSE
θ value	5.27518 (rank : 411)	NC score	0.011711 (rank : 449)
Query Neighborhood Hits	474	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UNW5, Q99PF2	Gene names	Tcfcp2l1, Crtr1
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1).

TITIN_HUMAN
θ value	5.27518 (rank : 412)	NC score	0.022041 (rank : 397)
Query Neighborhood Hits	474	Target Neighborhood Hits	2923	Shared Neighborhood Hits	181
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TROAP_HUMAN
θ value	5.27518 (rank : 413)	NC score	0.031971 (rank : 341)
Query Neighborhood Hits	474	Target Neighborhood Hits	258	Shared Neighborhood Hits	55
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ZXDA_HUMAN
θ value	5.27518 (rank : 414)	NC score	-0.007002 (rank : 527)
Query Neighborhood Hits	474	Target Neighborhood Hits	750	Shared Neighborhood Hits	18
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

AFF1_MOUSE
θ value	6.88961 (rank : 415)	NC score	0.037422 (rank : 318)
Query Neighborhood Hits	474	Target Neighborhood Hits	351	Shared Neighborhood Hits	68
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AFF4_HUMAN
θ value	6.88961 (rank : 416)	NC score	0.027422 (rank : 365)
Query Neighborhood Hits	474	Target Neighborhood Hits	611	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ANKS1_MOUSE
θ value	6.88961 (rank : 417)	NC score	0.008303 (rank : 474)
Query Neighborhood Hits	474	Target Neighborhood Hits	453	Shared Neighborhood Hits	22
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

BCAR1_HUMAN
θ value	6.88961 (rank : 418)	NC score	0.039832 (rank : 309)
Query Neighborhood Hits	474	Target Neighborhood Hits	554	Shared Neighborhood Hits	94
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	6.88961 (rank : 419)	NC score	0.032275 (rank : 338)
Query Neighborhood Hits	474	Target Neighborhood Hits	438	Shared Neighborhood Hits	79
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CT174_HUMAN
θ value	6.88961 (rank : 420)	NC score	0.017384 (rank : 424)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DAB1_MOUSE
θ value	6.88961 (rank : 421)	NC score	0.012689 (rank : 446)
Query Neighborhood Hits	474	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

EFS_HUMAN
θ value	6.88961 (rank : 422)	NC score	0.034559 (rank : 324)
Query Neighborhood Hits	474	Target Neighborhood Hits	348	Shared Neighborhood Hits	48
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	6.88961 (rank : 423)	NC score	0.039986 (rank : 308)
Query Neighborhood Hits	474	Target Neighborhood Hits	389	Shared Neighborhood Hits	60
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ERRFI_HUMAN
θ value	6.88961 (rank : 424)	NC score	0.011593 (rank : 450)
Query Neighborhood Hits	474	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

EVI1_HUMAN
θ value	6.88961 (rank : 425)	NC score	-0.005511 (rank : 526)
Query Neighborhood Hits	474	Target Neighborhood Hits	924	Shared Neighborhood Hits	39
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

HERC2_MOUSE
θ value	6.88961 (rank : 426)	NC score	0.003082 (rank : 499)
Query Neighborhood Hits	474	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HNF3G_HUMAN
θ value	6.88961 (rank : 427)	NC score	0.001077 (rank : 512)
Query Neighborhood Hits	474	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	P55318, Q9UMW9	Gene names	FOXA3, HNF3G, TCF3G
Domain Architecture
Description	Hepatocyte nuclear factor 3-gamma (HNF-3G) (Forkhead box protein A3) (Fork head-related protein FKH H3).

HXC4_HUMAN
θ value	6.88961 (rank : 428)	NC score	-0.001538 (rank : 521)
Query Neighborhood Hits	474	Target Neighborhood Hits	361	Shared Neighborhood Hits	10
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

LIRB4_HUMAN
θ value	6.88961 (rank : 429)	NC score	0.002989 (rank : 501)
Query Neighborhood Hits	474	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

LRC8E_HUMAN
θ value	6.88961 (rank : 430)	NC score	0.029129 (rank : 353)
Query Neighborhood Hits	474	Target Neighborhood Hits	259	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NSJ5, Q2YDY3, Q7L236, Q8N3B0, Q9H5H8	Gene names	LRRC8E
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

NEK1_MOUSE
θ value	6.88961 (rank : 431)	NC score	-0.000365 (rank : 516)
Query Neighborhood Hits	474	Target Neighborhood Hits	1311	Shared Neighborhood Hits	56
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

PRG4_MOUSE
θ value	6.88961 (rank : 432)	NC score	0.060866 (rank : 249)
Query Neighborhood Hits	474	Target Neighborhood Hits	624	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RD23B_MOUSE
θ value	6.88961 (rank : 433)	NC score	0.013560 (rank : 444)
Query Neighborhood Hits	474	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RTN4_HUMAN
θ value	6.88961 (rank : 434)	NC score	0.021263 (rank : 404)
Query Neighborhood Hits	474	Target Neighborhood Hits	357	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SCEL_HUMAN
θ value	6.88961 (rank : 435)	NC score	0.014970 (rank : 435)
Query Neighborhood Hits	474	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SCML2_HUMAN
θ value	6.88961 (rank : 436)	NC score	0.007157 (rank : 482)
Query Neighborhood Hits	474	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQR0, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5	Gene names	SCML2
Domain Architecture
Description	Sex comb on midleg-like protein 2.

SDC4_HUMAN
θ value	6.88961 (rank : 437)	NC score	0.008215 (rank : 475)
Query Neighborhood Hits	474	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P31431, O00773, Q16833	Gene names	SDC4
Domain Architecture
Description	Syndecan-4 precursor (SYND4) (Amphiglycan) (Ryudocan core protein).

SOCS6_MOUSE
θ value	6.88961 (rank : 438)	NC score	0.009359 (rank : 466)
Query Neighborhood Hits	474	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

TLE3_HUMAN
θ value	6.88961 (rank : 439)	NC score	0.002479 (rank : 505)
Query Neighborhood Hits	474	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

ZN438_HUMAN
θ value	6.88961 (rank : 440)	NC score	0.000964 (rank : 513)
Query Neighborhood Hits	474	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

1C16_HUMAN
θ value	8.99809 (rank : 441)	NC score	-0.003986 (rank : 522)
Query Neighborhood Hits	474	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q29960, O78091, O78202, Q29862, Q29959, Q9MY74, Q9MYI3, Q9TNZ8	Gene names	HLA-C, HLAC
Domain Architecture
Description	HLA class I histocompatibility antigen, Cw-16 alpha chain precursor (MHC class I antigen Cw*16).

BAG3_MOUSE
θ value	8.99809 (rank : 442)	NC score	0.056206 (rank : 263)
Query Neighborhood Hits	474	Target Neighborhood Hits	513	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BCR_HUMAN
θ value	8.99809 (rank : 443)	NC score	0.001662 (rank : 510)
Query Neighborhood Hits	474	Target Neighborhood Hits	204	Shared Neighborhood Hits	12
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CAC1B_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.004414 (rank : 496)
Query Neighborhood Hits	474	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CCD96_HUMAN
θ value	8.99809 (rank : 445)	NC score	0.009991 (rank : 461)
Query Neighborhood Hits	474	Target Neighborhood Hits	595	Shared Neighborhood Hits	39
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CD2AP_MOUSE
θ value	8.99809 (rank : 446)	NC score	0.027637 (rank : 362)
Query Neighborhood Hits	474	Target Neighborhood Hits	336	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CECR1_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.009073 (rank : 469)
Query Neighborhood Hits	474	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZK5, Q96K41	Gene names	CECR1
Domain Architecture
Description	Cat eye syndrome critical region protein 1 precursor.

CEP57_MOUSE
θ value	8.99809 (rank : 448)	NC score	0.002839 (rank : 503)
Query Neighborhood Hits	474	Target Neighborhood Hits	580	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

DYHC_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.007950 (rank : 479)
Query Neighborhood Hits	474	Target Neighborhood Hits	733	Shared Neighborhood Hits	30
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	8.99809 (rank : 450)	NC score	0.007955 (rank : 478)
Query Neighborhood Hits	474	Target Neighborhood Hits	729	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

GAK11_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.023343 (rank : 390)
Query Neighborhood Hits	474	Target Neighborhood Hits	409	Shared Neighborhood Hits	60
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.023417 (rank : 387)
Query Neighborhood Hits	474	Target Neighborhood Hits	415	Shared Neighborhood Hits	60
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GRASP_HUMAN
θ value	8.99809 (rank : 453)	NC score	0.228318 (rank : 143)
Query Neighborhood Hits	474	Target Neighborhood Hits	147	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	8.99809 (rank : 454)	NC score	0.224649 (rank : 146)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GSCR1_HUMAN
θ value	8.99809 (rank : 455)	NC score	0.040561 (rank : 306)
Query Neighborhood Hits	474	Target Neighborhood Hits	674	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HDAC5_HUMAN
θ value	8.99809 (rank : 456)	NC score	0.002118 (rank : 509)
Query Neighborhood Hits	474	Target Neighborhood Hits	353	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

K1210_HUMAN
θ value	8.99809 (rank : 457)	NC score	0.037934 (rank : 316)
Query Neighborhood Hits	474	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

K1683_HUMAN
θ value	8.99809 (rank : 458)	NC score	0.027572 (rank : 363)
Query Neighborhood Hits	474	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1802_HUMAN
θ value	8.99809 (rank : 459)	NC score	0.026931 (rank : 369)
Query Neighborhood Hits	474	Target Neighborhood Hits	1378	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAP1B_HUMAN
θ value	8.99809 (rank : 460)	NC score	0.042956 (rank : 299)
Query Neighborhood Hits	474	Target Neighborhood Hits	903	Shared Neighborhood Hits	92
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MLL3_HUMAN
θ value	8.99809 (rank : 461)	NC score	0.045447 (rank : 296)
Query Neighborhood Hits	474	Target Neighborhood Hits	1644	Shared Neighborhood Hits	152
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUC1_HUMAN
θ value	8.99809 (rank : 462)	NC score	0.048503 (rank : 287)
Query Neighborhood Hits	474	Target Neighborhood Hits	975	Shared Neighborhood Hits	124
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYO1E_HUMAN
θ value	8.99809 (rank : 463)	NC score	0.009128 (rank : 468)
Query Neighborhood Hits	474	Target Neighborhood Hits	293	Shared Neighborhood Hits	36
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

NCA11_HUMAN
θ value	8.99809 (rank : 464)	NC score	0.009208 (rank : 467)
Query Neighborhood Hits	474	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA12_HUMAN
θ value	8.99809 (rank : 465)	NC score	0.009406 (rank : 465)
Query Neighborhood Hits	474	Target Neighborhood Hits	437	Shared Neighborhood Hits	20
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

PARM1_HUMAN
θ value	8.99809 (rank : 466)	NC score	0.019277 (rank : 413)
Query Neighborhood Hits	474	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PP2CD_HUMAN
θ value	8.99809 (rank : 467)	NC score	0.005302 (rank : 493)
Query Neighborhood Hits	474	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	O15297	Gene names	PPM1D, WIP1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

ROBO3_HUMAN
θ value	8.99809 (rank : 468)	NC score	0.029249 (rank : 352)
Query Neighborhood Hits	474	Target Neighborhood Hits	570	Shared Neighborhood Hits	44
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SAFB2_HUMAN
θ value	8.99809 (rank : 469)	NC score	0.013695 (rank : 443)
Query Neighborhood Hits	474	Target Neighborhood Hits	720	Shared Neighborhood Hits	39
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SYNP2_MOUSE
θ value	8.99809 (rank : 470)	NC score	0.201285 (rank : 160)
Query Neighborhood Hits	474	Target Neighborhood Hits	252	Shared Neighborhood Hits	133
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYT6_HUMAN
θ value	8.99809 (rank : 471)	NC score	0.005788 (rank : 489)
Query Neighborhood Hits	474	Target Neighborhood Hits	138	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

TTC28_HUMAN
θ value	8.99809 (rank : 472)	NC score	0.010048 (rank : 460)
Query Neighborhood Hits	474	Target Neighborhood Hits	271	Shared Neighborhood Hits	35
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ZFAN5_MOUSE
θ value	8.99809 (rank : 473)	NC score	0.006321 (rank : 487)
Query Neighborhood Hits	474	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZN394_HUMAN
θ value	8.99809 (rank : 474)	NC score	-0.007082 (rank : 528)
Query Neighborhood Hits	474	Target Neighborhood Hits	752	Shared Neighborhood Hits	20
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

APXL_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.176671 (rank : 168)
Query Neighborhood Hits	474	Target Neighborhood Hits	553	Shared Neighborhood Hits	130
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CACB1_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.069486 (rank : 218)
Query Neighborhood Hits	474	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.072984 (rank : 212)
Query Neighborhood Hits	474	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB2_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.051992 (rank : 270)
Query Neighborhood Hits	474	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB3_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.067035 (rank : 225)
Query Neighborhood Hits	474	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.066325 (rank : 227)
Query Neighborhood Hits	474	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB4_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.067973 (rank : 224)
Query Neighborhood Hits	474	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB4_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.065926 (rank : 228)
Query Neighborhood Hits	474	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CARD9_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.055207 (rank : 265)
Query Neighborhood Hits	474	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CNKR2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.071826 (rank : 215)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.071975 (rank : 214)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CRK_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.069366 (rank : 219)
Query Neighborhood Hits	474	Target Neighborhood Hits	308	Shared Neighborhood Hits	43
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.069283 (rank : 220)
Query Neighborhood Hits	474	Target Neighborhood Hits	314	Shared Neighborhood Hits	45
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GIPC1_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.134132 (rank : 186)
Query Neighborhood Hits	474	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

GIPC1_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.139482 (rank : 184)
Query Neighborhood Hits	474	Target Neighborhood Hits	92	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

GIPC2_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.105451 (rank : 197)
Query Neighborhood Hits	474	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

GIPC2_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.060906 (rank : 248)
Query Neighborhood Hits	474	Target Neighborhood Hits	71	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GIPC3_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.061574 (rank : 243)
Query Neighborhood Hits	474	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.062105 (rank : 241)
Query Neighborhood Hits	474	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

GRB2_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.064424 (rank : 232)
Query Neighborhood Hits	474	Target Neighborhood Hits	310	Shared Neighborhood Hits	45
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.065100 (rank : 230)
Query Neighborhood Hits	474	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

KGUA_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.304837 (rank : 111)
Query Neighborhood Hits	474	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.310042 (rank : 110)
Query Neighborhood Hits	474	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LRRC1_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.051643 (rank : 271)
Query Neighborhood Hits	474	Target Neighborhood Hits	282	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.051522 (rank : 272)
Query Neighborhood Hits	474	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

NOLC1_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.053365 (rank : 269)
Query Neighborhood Hits	474	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOS1_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.171544 (rank : 170)
Query Neighborhood Hits	474	Target Neighborhood Hits	155	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NPHP1_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.050301 (rank : 278)
Query Neighborhood Hits	474	Target Neighborhood Hits	267	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

PAR6A_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.234163 (rank : 140)
Query Neighborhood Hits	474	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.234415 (rank : 139)
Query Neighborhood Hits	474	Target Neighborhood Hits	115	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6G_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.247544 (rank : 131)
Query Neighborhood Hits	474	Target Neighborhood Hits	159	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.245509 (rank : 133)
Query Neighborhood Hits	474	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDLI1_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.148962 (rank : 179)
Query Neighborhood Hits	474	Target Neighborhood Hits	213	Shared Neighborhood Hits	92
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.162482 (rank : 176)
Query Neighborhood Hits	474	Target Neighborhood Hits	245	Shared Neighborhood Hits	107
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI7_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.107079 (rank : 196)
Query Neighborhood Hits	474	Target Neighborhood Hits	279	Shared Neighborhood Hits	103
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD6_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.113183 (rank : 193)
Query Neighborhood Hits	474	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PROP_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.059367 (rank : 254)
Query Neighborhood Hits	474	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.057184 (rank : 259)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PSCBP_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.211799 (rank : 153)
Query Neighborhood Hits	474	Target Neighborhood Hits	118	Shared Neighborhood Hits	104
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RIMS1_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.178728 (rank : 167)
Query Neighborhood Hits	474	Target Neighborhood Hits	437	Shared Neighborhood Hits	136
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RNF41_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.061137 (rank : 246)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.061249 (rank : 244)
Query Neighborhood Hits	474	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SHAN1_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.122560 (rank : 190)
Query Neighborhood Hits	474	Target Neighborhood Hits	1041	Shared Neighborhood Hits	202
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.169456 (rank : 172)
Query Neighborhood Hits	474	Target Neighborhood Hits	346	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.149561 (rank : 178)
Query Neighborhood Hits	474	Target Neighborhood Hits	446	Shared Neighborhood Hits	150
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SRRM2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.068273 (rank : 223)
Query Neighborhood Hits	474	Target Neighborhood Hits	1296	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.069185 (rank : 221)
Query Neighborhood Hits	474	Target Neighborhood Hits	1470	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STAM1_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.055102 (rank : 267)
Query Neighborhood Hits	474	Target Neighborhood Hits	271	Shared Neighborhood Hits	42
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.063448 (rank : 234)
Query Neighborhood Hits	474	Target Neighborhood Hits	273	Shared Neighborhood Hits	43
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.057327 (rank : 258)
Query Neighborhood Hits	474	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SYNP2_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.168095 (rank : 173)
Query Neighborhood Hits	474	Target Neighborhood Hits	323	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TARA_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.050805 (rank : 276)
Query Neighborhood Hits	474	Target Neighborhood Hits	1133	Shared Neighborhood Hits	114
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WASIP_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.051306 (rank : 273)
Query Neighborhood Hits	474	Target Neighborhood Hits	392	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.062324 (rank : 240)
Query Neighborhood Hits	474	Target Neighborhood Hits	670	Shared Neighborhood Hits	114
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

Hits sorted by NC score

ZO1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	474	Target Neighborhood Hits	474	Shared Neighborhood Hits	474
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
NC score	0.975693 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	474	Target Neighborhood Hits	453	Shared Neighborhood Hits	280
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_MOUSE
NC score	0.917773 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	474	Target Neighborhood Hits	296	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
NC score	0.916742 (rank : 4)	θ value	3.97187e-173 (rank : 5)
Query Neighborhood Hits	474	Target Neighborhood Hits	219	Shared Neighborhood Hits	181
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO2_HUMAN
NC score	0.914099 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	474	Target Neighborhood Hits	289	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_MOUSE
NC score	0.912380 (rank : 6)	θ value	4.11978e-162 (rank : 6)
Query Neighborhood Hits	474	Target Neighborhood Hits	224	Shared Neighborhood Hits	182
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

DLG4_MOUSE
NC score	0.717925 (rank : 7)	θ value	1.0531e-32 (rank : 10)
Query Neighborhood Hits	474	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.717021 (rank : 8)	θ value	1.37539e-32 (rank : 11)
Query Neighborhood Hits	474	Target Neighborhood Hits	286	Shared Neighborhood Hits	175
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_MOUSE
NC score	0.712446 (rank : 9)	θ value	5.22648e-32 (rank : 13)
Query Neighborhood Hits	474	Target Neighborhood Hits	271	Shared Neighborhood Hits	171
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
NC score	0.712397 (rank : 10)	θ value	1.79631e-32 (rank : 12)
Query Neighborhood Hits	474	Target Neighborhood Hits	279	Shared Neighborhood Hits	171
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
NC score	0.709921 (rank : 11)	θ value	8.91499e-32 (rank : 14)
Query Neighborhood Hits	474	Target Neighborhood Hits	269	Shared Neighborhood Hits	172
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_MOUSE
NC score	0.709380 (rank : 12)	θ value	9.52487e-34 (rank : 7)
Query Neighborhood Hits	474	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG1_HUMAN
NC score	0.708743 (rank : 13)	θ value	2.77131e-33 (rank : 9)
Query Neighborhood Hits	474	Target Neighborhood Hits	290	Shared Neighborhood Hits	171
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_MOUSE
NC score	0.708525 (rank : 14)	θ value	4.89182e-30 (rank : 15)
Query Neighborhood Hits	474	Target Neighborhood Hits	274	Shared Neighborhood Hits	172
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

SYJ2B_HUMAN
NC score	0.643150 (rank : 15)	θ value	2.88788e-06 (rank : 59)
Query Neighborhood Hits	474	Target Neighborhood Hits	162	Shared Neighborhood Hits	146
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

INADL_MOUSE
NC score	0.632735 (rank : 16)	θ value	7.82807e-20 (rank : 16)
Query Neighborhood Hits	474	Target Neighborhood Hits	290	Shared Neighborhood Hits	183
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INADL_HUMAN
NC score	0.615185 (rank : 17)	θ value	1.9326e-10 (rank : 35)
Query Neighborhood Hits	474	Target Neighborhood Hits	260	Shared Neighborhood Hits	173
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MPDZ_MOUSE
NC score	0.600347 (rank : 18)	θ value	2.60593e-15 (rank : 18)
Query Neighborhood Hits	474	Target Neighborhood Hits	298	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.598871 (rank : 19)	θ value	8.38298e-14 (rank : 22)
Query Neighborhood Hits	474	Target Neighborhood Hits	261	Shared Neighborhood Hits	176
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PDZ11_MOUSE
NC score	0.589551 (rank : 20)	θ value	1.99992e-07 (rank : 47)
Query Neighborhood Hits	474	Target Neighborhood Hits	154	Shared Neighborhood Hits	134
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_HUMAN
NC score	0.588486 (rank : 21)	θ value	4.45536e-07 (rank : 51)
Query Neighborhood Hits	474	Target Neighborhood Hits	160	Shared Neighborhood Hits	138
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD2_HUMAN
NC score	0.559934 (rank : 22)	θ value	2.52405e-10 (rank : 37)
Query Neighborhood Hits	474	Target Neighborhood Hits	772	Shared Neighborhood Hits	239
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

USH1C_HUMAN
NC score	0.556683 (rank : 23)	θ value	0.000270298 (rank : 83)
Query Neighborhood Hits	474	Target Neighborhood Hits	327	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

LNX2_MOUSE
NC score	0.552329 (rank : 24)	θ value	7.34386e-10 (rank : 38)
Query Neighborhood Hits	474	Target Neighborhood Hits	407	Shared Neighborhood Hits	171
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

WHRN_HUMAN
NC score	0.549991 (rank : 25)	θ value	6.43352e-06 (rank : 64)
Query Neighborhood Hits	474	Target Neighborhood Hits	325	Shared Neighborhood Hits	187
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.545912 (rank : 26)	θ value	3.77169e-06 (rank : 61)
Query Neighborhood Hits	474	Target Neighborhood Hits	412	Shared Neighborhood Hits	197
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD7_HUMAN
NC score	0.540120 (rank : 27)	θ value	0.00298849 (rank : 103)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

LNX1_MOUSE
NC score	0.539244 (rank : 28)	θ value	4.0297e-08 (rank : 46)
Query Neighborhood Hits	474	Target Neighborhood Hits	377	Shared Neighborhood Hits	162
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
NC score	0.535610 (rank : 29)	θ value	3.64472e-09 (rank : 40)
Query Neighborhood Hits	474	Target Neighborhood Hits	389	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX1_HUMAN
NC score	0.534928 (rank : 30)	θ value	3.08544e-08 (rank : 44)
Query Neighborhood Hits	474	Target Neighborhood Hits	379	Shared Neighborhood Hits	156
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

GRIP2_HUMAN
NC score	0.534783 (rank : 31)	θ value	0.00134147 (rank : 95)
Query Neighborhood Hits	474	Target Neighborhood Hits	256	Shared Neighborhood Hits	174
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG5_HUMAN
NC score	0.531024 (rank : 32)	θ value	1.24399e-33 (rank : 8)
Query Neighborhood Hits	474	Target Neighborhood Hits	1088	Shared Neighborhood Hits	210
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

TX1B3_HUMAN
NC score	0.527619 (rank : 33)	θ value	0.00390308 (rank : 110)
Query Neighborhood Hits	474	Target Neighborhood Hits	161	Shared Neighborhood Hits	144
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

GRIP1_HUMAN
NC score	0.526250 (rank : 34)	θ value	9.29e-05 (rank : 76)
Query Neighborhood Hits	474	Target Neighborhood Hits	231	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MPP5_HUMAN
NC score	0.525222 (rank : 35)	θ value	4.91457e-14 (rank : 21)
Query Neighborhood Hits	474	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

LIN7C_HUMAN
NC score	0.525102 (rank : 36)	θ value	0.00390308 (rank : 106)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.525102 (rank : 37)	θ value	0.00390308 (rank : 107)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	168
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

MAGI1_HUMAN
NC score	0.524655 (rank : 38)	θ value	6.64225e-11 (rank : 29)
Query Neighborhood Hits	474	Target Neighborhood Hits	388	Shared Neighborhood Hits	190
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

TX1B3_MOUSE
NC score	0.524581 (rank : 39)	θ value	0.00390308 (rank : 111)
Query Neighborhood Hits	474	Target Neighborhood Hits	158	Shared Neighborhood Hits	141
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

LIN7B_HUMAN
NC score	0.524498 (rank : 40)	θ value	0.0113563 (rank : 127)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

MPP5_MOUSE
NC score	0.524434 (rank : 41)	θ value	1.86753e-13 (rank : 23)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

GRIP1_MOUSE
NC score	0.523839 (rank : 42)	θ value	0.000121331 (rank : 78)
Query Neighborhood Hits	474	Target Neighborhood Hits	241	Shared Neighborhood Hits	174
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LIN7B_MOUSE
NC score	0.522099 (rank : 43)	θ value	0.0148317 (rank : 131)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	170
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PAR3L_HUMAN
NC score	0.521906 (rank : 44)	θ value	0.000786445 (rank : 91)
Query Neighborhood Hits	474	Target Neighborhood Hits	297	Shared Neighborhood Hits	155
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

MAGI1_MOUSE
NC score	0.520105 (rank : 45)	θ value	3.64472e-09 (rank : 41)
Query Neighborhood Hits	474	Target Neighborhood Hits	403	Shared Neighborhood Hits	196
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

IL16_HUMAN
NC score	0.519684 (rank : 46)	θ value	5.44631e-05 (rank : 73)
Query Neighborhood Hits	474	Target Neighborhood Hits	207	Shared Neighborhood Hits	142
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LIN7A_HUMAN
NC score	0.517041 (rank : 47)	θ value	0.0252991 (rank : 139)
Query Neighborhood Hits	474	Target Neighborhood Hits	193	Shared Neighborhood Hits	167
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.516898 (rank : 48)	θ value	0.0252991 (rank : 140)
Query Neighborhood Hits	474	Target Neighborhood Hits	193	Shared Neighborhood Hits	167
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

USH1C_MOUSE
NC score	0.515306 (rank : 49)	θ value	4.1701e-05 (rank : 71)
Query Neighborhood Hits	474	Target Neighborhood Hits	557	Shared Neighborhood Hits	195
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PARD3_HUMAN
NC score	0.507679 (rank : 50)	θ value	0.000270298 (rank : 82)
Query Neighborhood Hits	474	Target Neighborhood Hits	312	Shared Neighborhood Hits	156
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

MAGI2_MOUSE
NC score	0.507013 (rank : 51)	θ value	1.06045e-08 (rank : 43)
Query Neighborhood Hits	474	Target Neighborhood Hits	370	Shared Neighborhood Hits	197
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PARD3_MOUSE
NC score	0.502577 (rank : 52)	θ value	0.00228821 (rank : 101)
Query Neighborhood Hits	474	Target Neighborhood Hits	290	Shared Neighborhood Hits	156
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SNTG2_HUMAN
NC score	0.500779 (rank : 53)	θ value	7.59969e-07 (rank : 53)
Query Neighborhood Hits	474	Target Neighborhood Hits	191	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

GOPC_MOUSE
NC score	0.498534 (rank : 54)	θ value	0.00509761 (rank : 113)
Query Neighborhood Hits	474	Target Neighborhood Hits	323	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

MAGI2_HUMAN
NC score	0.497904 (rank : 55)	θ value	2.61198e-07 (rank : 48)
Query Neighborhood Hits	474	Target Neighborhood Hits	373	Shared Neighborhood Hits	184
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

IL16_MOUSE
NC score	0.496807 (rank : 56)	θ value	0.00228821 (rank : 99)
Query Neighborhood Hits	474	Target Neighborhood Hits	189	Shared Neighborhood Hits	137
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZD1_MOUSE
NC score	0.492023 (rank : 57)	θ value	2.88788e-06 (rank : 58)
Query Neighborhood Hits	474	Target Neighborhood Hits	191	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PZRN4_HUMAN
NC score	0.490703 (rank : 58)	θ value	4.76016e-09 (rank : 42)
Query Neighborhood Hits	474	Target Neighborhood Hits	438	Shared Neighborhood Hits	155
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

GOPC_HUMAN
NC score	0.489740 (rank : 59)	θ value	0.00509761 (rank : 112)
Query Neighborhood Hits	474	Target Neighborhood Hits	377	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

PZRN3_HUMAN
NC score	0.489577 (rank : 60)	θ value	8.67504e-11 (rank : 31)
Query Neighborhood Hits	474	Target Neighborhood Hits	461	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
NC score	0.487547 (rank : 61)	θ value	1.133e-10 (rank : 32)
Query Neighborhood Hits	474	Target Neighborhood Hits	447	Shared Neighborhood Hits	152
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PDZD1_HUMAN
NC score	0.480959 (rank : 62)	θ value	0.000786445 (rank : 92)
Query Neighborhood Hits	474	Target Neighborhood Hits	190	Shared Neighborhood Hits	146
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTB2_MOUSE
NC score	0.475885 (rank : 63)	θ value	0.000602161 (rank : 89)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	146
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_HUMAN
NC score	0.474886 (rank : 64)	θ value	0.000602161 (rank : 88)
Query Neighborhood Hits	474	Target Neighborhood Hits	180	Shared Neighborhood Hits	146
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_MOUSE
NC score	0.474806 (rank : 65)	θ value	1.69304e-06 (rank : 57)
Query Neighborhood Hits	474	Target Neighborhood Hits	176	Shared Neighborhood Hits	147
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTA1_HUMAN
NC score	0.470867 (rank : 66)	θ value	9.92553e-07 (rank : 54)
Query Neighborhood Hits	474	Target Neighborhood Hits	186	Shared Neighborhood Hits	150
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
NC score	0.466804 (rank : 67)	θ value	1.69304e-06 (rank : 56)
Query Neighborhood Hits	474	Target Neighborhood Hits	170	Shared Neighborhood Hits	145
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTG1_MOUSE
NC score	0.456335 (rank : 68)	θ value	5.44631e-05 (rank : 74)
Query Neighborhood Hits	474	Target Neighborhood Hits	179	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.456260 (rank : 69)	θ value	9.29e-05 (rank : 77)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTB1_HUMAN
NC score	0.452236 (rank : 70)	θ value	0.000461057 (rank : 85)
Query Neighborhood Hits	474	Target Neighborhood Hits	157	Shared Neighborhood Hits	138
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.451467 (rank : 71)	θ value	0.000461057 (rank : 86)
Query Neighborhood Hits	474	Target Neighborhood Hits	160	Shared Neighborhood Hits	136
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

NHERF_MOUSE
NC score	0.442592 (rank : 72)	θ value	0.00298849 (rank : 102)
Query Neighborhood Hits	474	Target Neighborhood Hits	195	Shared Neighborhood Hits	150
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

EM55_MOUSE
NC score	0.440485 (rank : 73)	θ value	3.64472e-09 (rank : 39)
Query Neighborhood Hits	474	Target Neighborhood Hits	221	Shared Neighborhood Hits	113
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

PDZD3_HUMAN
NC score	0.433979 (rank : 74)	θ value	0.0330416 (rank : 144)
Query Neighborhood Hits	474	Target Neighborhood Hits	180	Shared Neighborhood Hits	151
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

MPP3_HUMAN
NC score	0.433392 (rank : 75)	θ value	0.125558 (rank : 165)
Query Neighborhood Hits	474	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

EM55_HUMAN
NC score	0.430924 (rank : 76)	θ value	1.69304e-06 (rank : 55)
Query Neighborhood Hits	474	Target Neighborhood Hits	228	Shared Neighborhood Hits	115
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

MPP3_MOUSE
NC score	0.428741 (rank : 77)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP2_MOUSE
NC score	0.421503 (rank : 78)	θ value	3.77169e-06 (rank : 60)
Query Neighborhood Hits	474	Target Neighborhood Hits	189	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NHRF2_HUMAN
NC score	0.419911 (rank : 79)	θ value	0.0330416 (rank : 143)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	159
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHERF_HUMAN
NC score	0.419399 (rank : 80)	θ value	0.0563607 (rank : 152)
Query Neighborhood Hits	474	Target Neighborhood Hits	190	Shared Neighborhood Hits	150
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

MPP2_HUMAN
NC score	0.418007 (rank : 81)	θ value	1.87187e-05 (rank : 66)
Query Neighborhood Hits	474	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP6_HUMAN
NC score	0.410960 (rank : 82)	θ value	0.000158464 (rank : 80)
Query Neighborhood Hits	474	Target Neighborhood Hits	180	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
NC score	0.403906 (rank : 83)	θ value	0.00228821 (rank : 100)
Query Neighborhood Hits	474	Target Neighborhood Hits	187	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

LAP4_HUMAN
NC score	0.403317 (rank : 84)	θ value	2.28291e-11 (rank : 26)
Query Neighborhood Hits	474	Target Neighborhood Hits	608	Shared Neighborhood Hits	195
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PDZK4_HUMAN
NC score	0.402804 (rank : 85)	θ value	2.44474e-05 (rank : 69)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	120
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

NHRF2_MOUSE
NC score	0.402736 (rank : 86)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	474	Target Neighborhood Hits	194	Shared Neighborhood Hits	161
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

MPP4_HUMAN
NC score	0.401494 (rank : 87)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	474	Target Neighborhood Hits	205	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

LAP4_MOUSE
NC score	0.401262 (rank : 88)	θ value	1.9326e-10 (rank : 36)
Query Neighborhood Hits	474	Target Neighborhood Hits	590	Shared Neighborhood Hits	199
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PDZK4_MOUSE
NC score	0.399535 (rank : 89)	θ value	0.000158464 (rank : 81)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	124
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

K1849_HUMAN
NC score	0.389016 (rank : 90)	θ value	0.000786445 (rank : 90)
Query Neighborhood Hits	474	Target Neighborhood Hits	220	Shared Neighborhood Hits	133
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PDZD3_MOUSE
NC score	0.388570 (rank : 91)	θ value	0.365318 (rank : 200)
Query Neighborhood Hits	474	Target Neighborhood Hits	171	Shared Neighborhood Hits	148
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

K1849_MOUSE
NC score	0.386041 (rank : 92)	θ value	0.00175202 (rank : 97)
Query Neighborhood Hits	474	Target Neighborhood Hits	335	Shared Neighborhood Hits	144
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MPP4_MOUSE
NC score	0.383044 (rank : 93)	θ value	0.0961366 (rank : 161)
Query Neighborhood Hits	474	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PTN13_HUMAN
NC score	0.361478 (rank : 94)	θ value	2.28291e-11 (rank : 27)
Query Neighborhood Hits	474	Target Neighborhood Hits	471	Shared Neighborhood Hits	178
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DVL3_MOUSE
NC score	0.360100 (rank : 95)	θ value	0.00665767 (rank : 121)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	117
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
NC score	0.359444 (rank : 96)	θ value	0.00665767 (rank : 120)
Query Neighborhood Hits	474	Target Neighborhood Hits	194	Shared Neighborhood Hits	116
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PTN13_MOUSE
NC score	0.356876 (rank : 97)	θ value	4.02038e-16 (rank : 17)
Query Neighborhood Hits	474	Target Neighborhood Hits	426	Shared Neighborhood Hits	174
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SDCB1_MOUSE
NC score	0.355952 (rank : 98)	θ value	0.0252991 (rank : 141)
Query Neighborhood Hits	474	Target Neighborhood Hits	144	Shared Neighborhood Hits	127
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB1_HUMAN
NC score	0.354160 (rank : 99)	θ value	0.0148317 (rank : 132)
Query Neighborhood Hits	474	Target Neighborhood Hits	150	Shared Neighborhood Hits	131
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

DVL1_HUMAN
NC score	0.353952 (rank : 100)	θ value	0.0193708 (rank : 135)
Query Neighborhood Hits	474	Target Neighborhood Hits	158	Shared Neighborhood Hits	116
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
NC score	0.351089 (rank : 101)	θ value	0.0193708 (rank : 136)
Query Neighborhood Hits	474	Target Neighborhood Hits	146	Shared Neighborhood Hits	113
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

NEB1_HUMAN
NC score	0.344689 (rank : 102)	θ value	0.00035302 (rank : 84)
Query Neighborhood Hits	474	Target Neighborhood Hits	829	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DVL2_MOUSE
NC score	0.344007 (rank : 103)	θ value	0.00665767 (rank : 119)
Query Neighborhood Hits	474	Target Neighborhood Hits	233	Shared Neighborhood Hits	124
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.343647 (rank : 104)	θ value	0.00665767 (rank : 118)
Query Neighborhood Hits	474	Target Neighborhood Hits	223	Shared Neighborhood Hits	120
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL1L_HUMAN
NC score	0.343511 (rank : 105)	θ value	0.0193708 (rank : 134)
Query Neighborhood Hits	474	Target Neighborhood Hits	146	Shared Neighborhood Hits	113
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

NEB2_HUMAN
NC score	0.338981 (rank : 106)	θ value	2.44474e-05 (rank : 67)
Query Neighborhood Hits	474	Target Neighborhood Hits	883	Shared Neighborhood Hits	151
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

AFAD_HUMAN
NC score	0.338887 (rank : 107)	θ value	1.81305 (rank : 267)
Query Neighborhood Hits	474	Target Neighborhood Hits	689	Shared Neighborhood Hits	166
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

NEB2_MOUSE
NC score	0.334379 (rank : 108)	θ value	2.44474e-05 (rank : 68)
Query Neighborhood Hits	474	Target Neighborhood Hits	889	Shared Neighborhood Hits	144
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RPGF6_HUMAN
NC score	0.322153 (rank : 109)	θ value	0.000786445 (rank : 94)
Query Neighborhood Hits	474	Target Neighborhood Hits	266	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

KGUA_MOUSE
NC score	0.310042 (rank : 110)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	474	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.304837 (rank : 111)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	474	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

APBA1_HUMAN
NC score	0.304658 (rank : 112)	θ value	2.36792 (rank : 294)
Query Neighborhood Hits	474	Target Neighborhood Hits	325	Shared Neighborhood Hits	147
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

SDCB2_MOUSE
NC score	0.301944 (rank : 113)	θ value	0.00509761 (rank : 116)
Query Neighborhood Hits	474	Target Neighborhood Hits	118	Shared Neighborhood Hits	104
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

PDLI2_HUMAN
NC score	0.298721 (rank : 114)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	474	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PICK1_MOUSE
NC score	0.298540 (rank : 115)	θ value	0.163984 (rank : 172)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	111
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.296386 (rank : 116)	θ value	0.163984 (rank : 171)
Query Neighborhood Hits	474	Target Neighborhood Hits	132	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APBA3_MOUSE
NC score	0.295495 (rank : 117)	θ value	0.00869519 (rank : 123)
Query Neighborhood Hits	474	Target Neighborhood Hits	174	Shared Neighborhood Hits	120
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA2_HUMAN
NC score	0.281201 (rank : 118)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	474	Target Neighborhood Hits	220	Shared Neighborhood Hits	148
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

SDCB2_HUMAN
NC score	0.280365 (rank : 119)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	474	Target Neighborhood Hits	121	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

APBA2_MOUSE
NC score	0.279741 (rank : 120)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	474	Target Neighborhood Hits	219	Shared Neighborhood Hits	140
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

RPGF2_HUMAN
NC score	0.279226 (rank : 121)	θ value	0.00665767 (rank : 122)
Query Neighborhood Hits	474	Target Neighborhood Hits	242	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

APBA3_HUMAN
NC score	0.278015 (rank : 122)	θ value	0.0961366 (rank : 158)
Query Neighborhood Hits	474	Target Neighborhood Hits	201	Shared Neighborhood Hits	128
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

STXB4_HUMAN
NC score	0.276300 (rank : 123)	θ value	0.62314 (rank : 218)
Query Neighborhood Hits	474	Target Neighborhood Hits	616	Shared Neighborhood Hits	111
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PDLI2_MOUSE
NC score	0.273339 (rank : 124)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	474	Target Neighborhood Hits	220	Shared Neighborhood Hits	113
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

SYP2L_HUMAN
NC score	0.267331 (rank : 125)	θ value	0.0330416 (rank : 145)
Query Neighborhood Hits	474	Target Neighborhood Hits	400	Shared Neighborhood Hits	148
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

STXB4_MOUSE
NC score	0.262444 (rank : 126)	θ value	5.27518 (rank : 404)
Query Neighborhood Hits	474	Target Neighborhood Hits	629	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PAR6B_MOUSE
NC score	0.258396 (rank : 127)	θ value	4.03905 (rank : 364)
Query Neighborhood Hits	474	Target Neighborhood Hits	128	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_HUMAN
NC score	0.256925 (rank : 128)	θ value	4.03905 (rank : 363)
Query Neighborhood Hits	474	Target Neighborhood Hits	126	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

ARHGB_HUMAN
NC score	0.252386 (rank : 129)	θ value	0.00665767 (rank : 117)
Query Neighborhood Hits	474	Target Neighborhood Hits	375	Shared Neighborhood Hits	159
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

RHPN1_MOUSE
NC score	0.251054 (rank : 130)	θ value	0.125558 (rank : 167)
Query Neighborhood Hits	474	Target Neighborhood Hits	154	Shared Neighborhood Hits	124
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PAR6G_HUMAN
NC score	0.247544 (rank : 131)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	474	Target Neighborhood Hits	159	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

CAR14_HUMAN
NC score	0.246909 (rank : 132)	θ value	3.41135e-07 (rank : 49)
Query Neighborhood Hits	474	Target Neighborhood Hits	449	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

PAR6G_MOUSE
NC score	0.245509 (rank : 133)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	474	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

ARHGC_HUMAN
NC score	0.244369 (rank : 134)	θ value	0.00175202 (rank : 96)
Query Neighborhood Hits	474	Target Neighborhood Hits	351	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LRRC7_HUMAN
NC score	0.243461 (rank : 135)	θ value	4.92598e-06 (rank : 62)
Query Neighborhood Hits	474	Target Neighborhood Hits	423	Shared Neighborhood Hits	123
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.242746 (rank : 136)	θ value	4.92598e-06 (rank : 63)
Query Neighborhood Hits	474	Target Neighborhood Hits	416	Shared Neighborhood Hits	123
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

ARHGC_MOUSE
NC score	0.239212 (rank : 137)	θ value	0.00390308 (rank : 105)
Query Neighborhood Hits	474	Target Neighborhood Hits	344	Shared Neighborhood Hits	142
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LAP2_HUMAN
NC score	0.234517 (rank : 138)	θ value	1.43324e-05 (rank : 65)
Query Neighborhood Hits	474	Target Neighborhood Hits	499	Shared Neighborhood Hits	122
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PAR6A_MOUSE
NC score	0.234415 (rank : 139)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	474	Target Neighborhood Hits	115	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6A_HUMAN
NC score	0.234163 (rank : 140)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	474	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

RHPN1_HUMAN
NC score	0.229299 (rank : 141)	θ value	1.81305 (rank : 288)
Query Neighborhood Hits	474	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

UNC5A_HUMAN
NC score	0.228957 (rank : 142)	θ value	1.133e-10 (rank : 33)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

GRASP_HUMAN
NC score	0.228318 (rank : 143)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	474	Target Neighborhood Hits	147	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

CAR11_HUMAN
NC score	0.227183 (rank : 144)	θ value	4.0297e-08 (rank : 45)
Query Neighborhood Hits	474	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

LAP2_MOUSE
NC score	0.225975 (rank : 145)	θ value	4.1701e-05 (rank : 70)
Query Neighborhood Hits	474	Target Neighborhood Hits	482	Shared Neighborhood Hits	117
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GRASP_MOUSE
NC score	0.224649 (rank : 146)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

CAR14_MOUSE
NC score	0.219100 (rank : 147)	θ value	3.41135e-07 (rank : 50)
Query Neighborhood Hits	474	Target Neighborhood Hits	526	Shared Neighborhood Hits	42
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

UNC5C_MOUSE
NC score	0.218237 (rank : 148)	θ value	1.68911e-14 (rank : 20)
Query Neighborhood Hits	474	Target Neighborhood Hits	225	Shared Neighborhood Hits	25
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.218012 (rank : 149)	θ value	1.68911e-14 (rank : 19)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

NOS1_HUMAN
NC score	0.215674 (rank : 150)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	474	Target Neighborhood Hits	218	Shared Neighborhood Hits	133
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

UNC5B_MOUSE
NC score	0.213826 (rank : 151)	θ value	1.58096e-12 (rank : 24)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.212683 (rank : 152)	θ value	2.0648e-12 (rank : 25)
Query Neighborhood Hits	474	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

PSCBP_MOUSE
NC score	0.211799 (rank : 153)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	474	Target Neighborhood Hits	118	Shared Neighborhood Hits	104
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PSCBP_HUMAN
NC score	0.209273 (rank : 154)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	474	Target Neighborhood Hits	123	Shared Neighborhood Hits	105
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

CAR10_MOUSE
NC score	0.208917 (rank : 155)	θ value	7.59969e-07 (rank : 52)
Query Neighborhood Hits	474	Target Neighborhood Hits	407	Shared Neighborhood Hits	32
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

UNC5A_MOUSE
NC score	0.207214 (rank : 156)	θ value	6.64225e-11 (rank : 30)
Query Neighborhood Hits	474	Target Neighborhood Hits	203	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PRAX_MOUSE
NC score	0.204927 (rank : 157)	θ value	0.000602161 (rank : 87)
Query Neighborhood Hits	474	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

UNC5D_MOUSE
NC score	0.203142 (rank : 158)	θ value	2.98157e-11 (rank : 28)
Query Neighborhood Hits	474	Target Neighborhood Hits	268	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

RGS12_HUMAN
NC score	0.201804 (rank : 159)	θ value	4.03905 (rank : 366)
Query Neighborhood Hits	474	Target Neighborhood Hits	333	Shared Neighborhood Hits	134
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SYNP2_MOUSE
NC score	0.201285 (rank : 160)	θ value	8.99809 (rank : 470)
Query Neighborhood Hits	474	Target Neighborhood Hits	252	Shared Neighborhood Hits	133
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

UNC5D_HUMAN
NC score	0.201273 (rank : 161)	θ value	1.47974e-10 (rank : 34)
Query Neighborhood Hits	474	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

SYP2L_MOUSE
NC score	0.193236 (rank : 162)	θ value	0.0563607 (rank : 154)
Query Neighborhood Hits	474	Target Neighborhood Hits	289	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PCLO_MOUSE
NC score	0.189754 (rank : 163)	θ value	0.00175202 (rank : 98)
Query Neighborhood Hits	474	Target Neighborhood Hits	2275	Shared Neighborhood Hits	291
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDLI4_MOUSE
NC score	0.187446 (rank : 164)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	474	Target Neighborhood Hits	233	Shared Neighborhood Hits	104
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_HUMAN
NC score	0.185524 (rank : 165)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	474	Target Neighborhood Hits	199	Shared Neighborhood Hits	101
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PRAX_HUMAN
NC score	0.181876 (rank : 166)	θ value	0.000786445 (rank : 93)
Query Neighborhood Hits	474	Target Neighborhood Hits	215	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

RIMS1_HUMAN
NC score	0.178728 (rank : 167)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	474	Target Neighborhood Hits	437	Shared Neighborhood Hits	136
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

APXL_HUMAN
NC score	0.176671 (rank : 168)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	474	Target Neighborhood Hits	553	Shared Neighborhood Hits	130
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PDLI3_MOUSE
NC score	0.172309 (rank : 169)	θ value	0.163984 (rank : 169)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	98
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

NOS1_MOUSE
NC score	0.171544 (rank : 170)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	474	Target Neighborhood Hits	155	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

CAR10_HUMAN
NC score	0.169764 (rank : 171)	θ value	5.44631e-05 (rank : 72)
Query Neighborhood Hits	474	Target Neighborhood Hits	569	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

SHAN2_HUMAN
NC score	0.169456 (rank : 172)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	474	Target Neighborhood Hits	346	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SYNP2_HUMAN
NC score	0.168095 (rank : 173)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	474	Target Neighborhood Hits	323	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

RIMS2_HUMAN
NC score	0.167161 (rank : 174)	θ value	0.163984 (rank : 175)
Query Neighborhood Hits	474	Target Neighborhood Hits	342	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.166854 (rank : 175)	θ value	0.163984 (rank : 176)
Query Neighborhood Hits	474	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

PDLI4_HUMAN
NC score	0.162482 (rank : 176)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	474	Target Neighborhood Hits	245	Shared Neighborhood Hits	107
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI1_HUMAN
NC score	0.154391 (rank : 177)	θ value	1.81305 (rank : 282)
Query Neighborhood Hits	474	Target Neighborhood Hits	242	Shared Neighborhood Hits	92
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

SHAN2_MOUSE
NC score	0.149561 (rank : 178)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	474	Target Neighborhood Hits	446	Shared Neighborhood Hits	150
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PDLI1_MOUSE
NC score	0.148962 (rank : 179)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	474	Target Neighborhood Hits	213	Shared Neighborhood Hits	92
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

LDB3_MOUSE
NC score	0.147596 (rank : 180)	θ value	1.38821 (rank : 254)
Query Neighborhood Hits	474	Target Neighborhood Hits	510	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI5_HUMAN
NC score	0.145464 (rank : 181)	θ value	0.163984 (rank : 170)
Query Neighborhood Hits	474	Target Neighborhood Hits	322	Shared Neighborhood Hits	116
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LDB3_HUMAN
NC score	0.145247 (rank : 182)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	474	Target Neighborhood Hits	497	Shared Neighborhood Hits	135
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

CSKP_HUMAN
NC score	0.142272 (rank : 183)	θ value	7.1131e-05 (rank : 75)
Query Neighborhood Hits	474	Target Neighborhood Hits	1022	Shared Neighborhood Hits	122
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

GIPC1_MOUSE
NC score	0.139482 (rank : 184)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	474	Target Neighborhood Hits	92	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

PDLI5_MOUSE
NC score	0.139162 (rank : 185)	θ value	0.365318 (rank : 199)
Query Neighborhood Hits	474	Target Neighborhood Hits	287	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

GIPC1_HUMAN
NC score	0.134132 (rank : 186)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	474	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PDLI7_HUMAN
NC score	0.133877 (rank : 187)	θ value	1.06291 (rank : 241)
Query Neighborhood Hits	474	Target Neighborhood Hits	547	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

CSKP_MOUSE
NC score	0.130958 (rank : 188)	θ value	0.0961366 (rank : 159)
Query Neighborhood Hits	474	Target Neighborhood Hits	1027	Shared Neighborhood Hits	124
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PTN4_HUMAN
NC score	0.127553 (rank : 189)	θ value	0.163984 (rank : 173)
Query Neighborhood Hits	474	Target Neighborhood Hits	303	Shared Neighborhood Hits	125
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SHAN1_HUMAN
NC score	0.122560 (rank : 190)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	474	Target Neighborhood Hits	1041	Shared Neighborhood Hits	202
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

LMO7_HUMAN
NC score	0.122309 (rank : 191)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	474	Target Neighborhood Hits	507	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PDZD8_HUMAN
NC score	0.117505 (rank : 192)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	474	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PDZD6_HUMAN
NC score	0.113183 (rank : 193)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	474	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PTN3_HUMAN
NC score	0.112273 (rank : 194)	θ value	5.27518 (rank : 393)
Query Neighborhood Hits	474	Target Neighborhood Hits	258	Shared Neighborhood Hits	114
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SRRM1_HUMAN
NC score	0.108065 (rank : 195)	θ value	0.0193708 (rank : 137)
Query Neighborhood Hits	474	Target Neighborhood Hits	690	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PDLI7_MOUSE
NC score	0.107079 (rank : 196)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	474	Target Neighborhood Hits	279	Shared Neighborhood Hits	103
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GIPC2_HUMAN
NC score	0.105451 (rank : 197)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	474	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

HTRA3_MOUSE
NC score	0.104988 (rank : 198)	θ value	0.62314 (rank : 207)
Query Neighborhood Hits	474	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

TXND2_HUMAN
NC score	0.103433 (rank : 199)	θ value	0.000121331 (rank : 79)
Query Neighborhood Hits	474	Target Neighborhood Hits	793	Shared Neighborhood Hits	120
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SRRM1_MOUSE
NC score	0.103328 (rank : 200)	θ value	0.00869519 (rank : 125)
Query Neighborhood Hits	474	Target Neighborhood Hits	966	Shared Neighborhood Hits	137
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

HTRA3_HUMAN
NC score	0.097625 (rank : 201)	θ value	0.125558 (rank : 164)
Query Neighborhood Hits	474	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

MDC1_MOUSE
NC score	0.091335 (rank : 202)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	474	Target Neighborhood Hits	998	Shared Neighborhood Hits	139
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC7_HUMAN
NC score	0.088497 (rank : 203)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	474	Target Neighborhood Hits	538	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
NC score	0.085322 (rank : 204)	θ value	0.125558 (rank : 166)
Query Neighborhood Hits	474	Target Neighborhood Hits	1866	Shared Neighborhood Hits	182
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RGS3_MOUSE
NC score	0.084794 (rank : 205)	θ value	1.81305 (rank : 287)
Query Neighborhood Hits	474	Target Neighborhood Hits	1621	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TMM51_MOUSE
NC score	0.081880 (rank : 206)	θ value	0.00390308 (rank : 109)
Query Neighborhood Hits	474	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LG1, Q3TPZ3	Gene names	Tmem51
Domain Architecture	No domain graphic available
Description	Transmembrane protein 51.

TIAM1_HUMAN
NC score	0.078703 (rank : 207)	θ value	0.813845 (rank : 236)
Query Neighborhood Hits	474	Target Neighborhood Hits	225	Shared Neighborhood Hits	66
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MDC1_HUMAN
NC score	0.078610 (rank : 208)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	474	Target Neighborhood Hits	1446	Shared Neighborhood Hits	158
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CJ078_MOUSE
NC score	0.076784 (rank : 209)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	474	Target Neighborhood Hits	559	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ARI1A_HUMAN
NC score	0.075940 (rank : 210)	θ value	0.0431538 (rank : 148)
Query Neighborhood Hits	474	Target Neighborhood Hits	787	Shared Neighborhood Hits	114
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

RGS3_HUMAN
NC score	0.075075 (rank : 211)	θ value	0.365318 (rank : 202)
Query Neighborhood Hits	474	Target Neighborhood Hits	1375	Shared Neighborhood Hits	186
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CACB1_MOUSE
NC score	0.072984 (rank : 212)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	474	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

TARA_HUMAN
NC score	0.072644 (rank : 213)	θ value	0.00298849 (rank : 104)
Query Neighborhood Hits	474	Target Neighborhood Hits	1626	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CNKR2_MOUSE
NC score	0.071975 (rank : 214)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.071826 (rank : 215)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	474	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

ATX2L_HUMAN
NC score	0.070202 (rank : 216)	θ value	0.0193708 (rank : 133)
Query Neighborhood Hits	474	Target Neighborhood Hits	443	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

PCLO_HUMAN
NC score	0.069841 (rank : 217)	θ value	0.365318 (rank : 198)
Query Neighborhood Hits	474	Target Neighborhood Hits	2046	Shared Neighborhood Hits	209
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CACB1_HUMAN
NC score	0.069486 (rank : 218)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	474	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CRK_HUMAN
NC score	0.069366 (rank : 219)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	474	Target Neighborhood Hits	308	Shared Neighborhood Hits	43
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
NC score	0.069283 (rank : 220)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	474	Target Neighborhood Hits	314	Shared Neighborhood Hits	45
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

SRRM2_MOUSE
NC score	0.069185 (rank : 221)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	474	Target Neighborhood Hits	1470	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PRG4_HUMAN
NC score	0.068752 (rank : 222)	θ value	0.0563607 (rank : 153)
Query Neighborhood Hits	474	Target Neighborhood Hits	764	Shared Neighborhood Hits	109
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM2_HUMAN
NC score	0.068273 (rank : 223)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	474	Target Neighborhood Hits	1296	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CACB4_HUMAN
NC score	0.067973 (rank : 224)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	474	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB3_HUMAN
NC score	0.067035 (rank : 225)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	474	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

TGON2_HUMAN
NC score	0.066547 (rank : 226)	θ value	0.813845 (rank : 235)
Query Neighborhood Hits	474	Target Neighborhood Hits	1037	Shared Neighborhood Hits	123
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CACB3_MOUSE
NC score	0.066325 (rank : 227)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	474	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB4_MOUSE
NC score	0.065926 (rank : 228)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	474	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

IWS1_HUMAN
NC score	0.065685 (rank : 229)	θ value	0.0330416 (rank : 142)
Query Neighborhood Hits	474	Target Neighborhood Hits	1241	Shared Neighborhood Hits	117
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GRB2_MOUSE
NC score	0.065100 (rank : 230)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	474	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

RBBP6_HUMAN
NC score	0.065005 (rank : 231)	θ value	0.163984 (rank : 174)
Query Neighborhood Hits	474	Target Neighborhood Hits	1135	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

GRB2_HUMAN
NC score	0.064424 (rank : 232)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	474	Target Neighborhood Hits	310	Shared Neighborhood Hits	45
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

HTRA1_HUMAN
NC score	0.063727 (rank : 233)	θ value	1.38821 (rank : 252)
Query Neighborhood Hits	474	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

STAM1_MOUSE
NC score	0.063448 (rank : 234)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	474	Target Neighborhood Hits	273	Shared Neighborhood Hits	43
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

BLNK_MOUSE
NC score	0.063220 (rank : 235)	θ value	0.21417 (rank : 179)
Query Neighborhood Hits	474	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

RPB1_MOUSE
NC score	0.063088 (rank : 236)	θ value	0.0431538 (rank : 149)
Query Neighborhood Hits	474	Target Neighborhood Hits	363	Shared Neighborhood Hits	56
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

WASIP_HUMAN
NC score	0.063053 (rank : 237)	θ value	0.21417 (rank : 182)
Query Neighborhood Hits	474	Target Neighborhood Hits	458	Shared Neighborhood Hits	76
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TCOF_MOUSE
NC score	0.062656 (rank : 238)	θ value	0.62314 (rank : 219)
Query Neighborhood Hits	474	Target Neighborhood Hits	471	Shared Neighborhood Hits	75
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

HTRA1_MOUSE
NC score	0.062366 (rank : 239)	θ value	1.81305 (rank : 274)
Query Neighborhood Hits	474	Target Neighborhood Hits	140	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

YLPM1_HUMAN
NC score	0.062324 (rank : 240)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	474	Target Neighborhood Hits	670	Shared Neighborhood Hits	114
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

GIPC3_MOUSE
NC score	0.062105 (rank : 241)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	474	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

IWS1_MOUSE
NC score	0.062032 (rank : 242)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	474	Target Neighborhood Hits	1258	Shared Neighborhood Hits	129
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GIPC3_HUMAN
NC score	0.061574 (rank : 243)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	474	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

RNF41_MOUSE
NC score	0.061249 (rank : 244)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	474	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TIAM1_MOUSE
NC score	0.061219 (rank : 245)	θ value	0.813845 (rank : 237)
Query Neighborhood Hits	474	Target Neighborhood Hits	205	Shared Neighborhood Hits	48
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

RNF41_HUMAN
NC score	0.061137 (rank : 246)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	474	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RPB1_HUMAN
NC score	0.060931 (rank : 247)	θ value	0.0736092 (rank : 156)
Query Neighborhood Hits	474	Target Neighborhood Hits	362	Shared Neighborhood Hits	57
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

GIPC2_MOUSE
NC score	0.060906 (rank : 248)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	474	Target Neighborhood Hits	71	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

PRG4_MOUSE
NC score	0.060866 (rank : 249)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	474	Target Neighborhood Hits	624	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RBBP6_MOUSE
NC score	0.060452 (rank : 250)	θ value	0.365318 (rank : 201)
Query Neighborhood Hits	474	Target Neighborhood Hits	1014	Shared Neighborhood Hits	96
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ZCPW1_MOUSE
NC score	0.060398 (rank : 251)	θ value	0.0961366 (rank : 162)
Query Neighborhood Hits	474	Target Neighborhood Hits	307	Shared Neighborhood Hits	39
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ATX2L_MOUSE
NC score	0.060309 (rank : 252)	θ value	0.0252991 (rank : 138)
Query Neighborhood Hits	474	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

AKAP2_MOUSE
NC score	0.059828 (rank : 253)	θ value	0.0431538 (rank : 146)
Query Neighborhood Hits	474	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

PROP_HUMAN
NC score	0.059367 (rank : 254)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	474	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

LCP2_HUMAN
NC score	0.059231 (rank : 255)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	474	Target Neighborhood Hits	531	Shared Neighborhood Hits	100
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SELPL_MOUSE
NC score	0.057455 (rank : 256)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	474	Target Neighborhood Hits	588	Shared Neighborhood Hits	93
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

YLPM1_MOUSE
NC score	0.057400 (rank : 257)	θ value	0.0431538 (rank : 150)
Query Neighborhood Hits	474	Target Neighborhood Hits	505	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

STAM2_MOUSE
NC score	0.057327 (rank : 258)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	474	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

PROP_MOUSE
NC score	0.057184 (rank : 259)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	474	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

TFG_HUMAN
NC score	0.056454 (rank : 260)	θ value	0.365318 (rank : 203)
Query Neighborhood Hits	474	Target Neighborhood Hits	122	Shared Neighborhood Hits	19
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

MAP1A_HUMAN
NC score	0.056341 (rank : 261)	θ value	0.0113563 (rank : 128)
Query Neighborhood Hits	474	Target Neighborhood Hits	1626	Shared Neighborhood Hits	134
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TMM51_HUMAN
NC score	0.056244 (rank : 262)	θ value	0.21417 (rank : 181)
Query Neighborhood Hits	474	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NW97	Gene names	TMEM51, C1orf72
Domain Architecture	No domain graphic available
Description	Transmembrane protein 51.

BAG3_MOUSE
NC score	0.056206 (rank : 263)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	474	Target Neighborhood Hits	513	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

NCOA6_HUMAN
NC score	0.055331 (rank : 264)	θ value	1.81305 (rank : 278)
Query Neighborhood Hits	474	Target Neighborhood Hits	1202	Shared Neighborhood Hits	155
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CARD9_HUMAN
NC score	0.055207 (rank : 265)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	474	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

BSN_MOUSE
NC score	0.055203 (rank : 266)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	474	Target Neighborhood Hits	2057	Shared Neighborhood Hits	199
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

STAM1_HUMAN
NC score	0.055102 (rank : 267)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	474	Target Neighborhood Hits	271	Shared Neighborhood Hits	42
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

NFH_MOUSE
NC score	0.053710 (rank : 268)	θ value	5.27518 (rank : 390)
Query Neighborhood Hits	474	Target Neighborhood Hits	2247	Shared Neighborhood Hits	191
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
NC score	0.053365 (rank : 269)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	474	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CACB2_HUMAN
NC score	0.051992 (rank : 270)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	474	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

LRRC1_HUMAN
NC score	0.051643 (rank : 271)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	474	Target Neighborhood Hits	282	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
NC score	0.051522 (rank : 272)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	474	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

WASIP_MOUSE
NC score	0.051306 (rank : 273)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	474	Target Neighborhood Hits	392	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

NPAS4_MOUSE
NC score	0.051111 (rank : 274)	θ value	0.163984 (rank : 168)
Query Neighborhood Hits	474	Target Neighborhood Hits	245	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NFIB_MOUSE
NC score	0.051099 (rank : 275)	θ value	0.00509761 (rank : 115)
Query Neighborhood Hits	474	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

TARA_MOUSE
NC score	0.050805 (rank : 276)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	474	Target Neighborhood Hits	1133	Shared Neighborhood Hits	114
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NFIB_HUMAN
NC score	0.050665 (rank : 277)	θ value	0.00390308 (rank : 108)
Query Neighborhood Hits	474	Target Neighborhood Hits	66	Shared Neighborhood Hits	17
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NPHP1_MOUSE
NC score	0.050301 (rank : 278)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	474	Target Neighborhood Hits	267	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

MAST4_HUMAN
NC score	0.050275 (rank : 279)	θ value	0.813845 (rank : 228)
Query Neighborhood Hits	474	Target Neighborhood Hits	1804	Shared Neighborhood Hits	226
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

K1914_MOUSE
NC score	0.050194 (rank : 280)	θ value	0.0113563 (rank : 126)
Query Neighborhood Hits	474	Target Neighborhood Hits	216	Shared Neighborhood Hits	28
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

SET1A_HUMAN
NC score	0.050112 (rank : 281)	θ value	4.03905 (rank : 367)
Query Neighborhood Hits	474	Target Neighborhood Hits	690	Shared Neighborhood Hits	104
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

KI67_HUMAN
NC score	0.049605 (rank : 282)	θ value	2.36792 (rank : 299)
Query Neighborhood Hits	474	Target Neighborhood Hits	581	Shared Neighborhood Hits	82
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CBP_HUMAN
NC score	0.049163 (rank : 283)	θ value	1.81305 (rank : 270)
Query Neighborhood Hits	474	Target Neighborhood Hits	941	Shared Neighborhood Hits	115
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RERE_MOUSE
NC score	0.049059 (rank : 284)	θ value	0.62314 (rank : 214)
Query Neighborhood Hits	474	Target Neighborhood Hits	785	Shared Neighborhood Hits	107
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CBP_MOUSE
NC score	0.048921 (rank : 285)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	474	Target Neighborhood Hits	1051	Shared Neighborhood Hits	135
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CN155_HUMAN
NC score	0.048813 (rank : 286)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	474	Target Neighborhood Hits	385	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MUC1_HUMAN
NC score	0.048503 (rank : 287)	θ value	8.99809 (rank : 462)
Query Neighborhood Hits	474	Target Neighborhood Hits	975	Shared Neighborhood Hits	124
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

LAD1_HUMAN
NC score	0.047564 (rank : 288)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	474	Target Neighborhood Hits	441	Shared Neighborhood Hits	79
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

ENL_HUMAN
NC score	0.047176 (rank : 289)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	474	Target Neighborhood Hits	305	Shared Neighborhood Hits	54
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ANK2_HUMAN
NC score	0.046289 (rank : 290)	θ value	0.0148317 (rank : 130)
Query Neighborhood Hits	474	Target Neighborhood Hits	1615	Shared Neighborhood Hits	156
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

EP300_HUMAN
NC score	0.046190 (rank : 291)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	474	Target Neighborhood Hits	821	Shared Neighborhood Hits	116
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ASPP1_MOUSE
NC score	0.045992 (rank : 292)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	474	Target Neighborhood Hits	1244	Shared Neighborhood Hits	116
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AUTS2_HUMAN
NC score	0.045614 (rank : 293)	θ value	1.38821 (rank : 248)
Query Neighborhood Hits	474	Target Neighborhood Hits	342	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SVIL_MOUSE
NC score	0.045602 (rank : 294)	θ value	1.06291 (rank : 243)
Query Neighborhood Hits	474	Target Neighborhood Hits	439	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

PTN23_MOUSE
NC score	0.045518 (rank : 295)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	474	Target Neighborhood Hits	726	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MLL3_HUMAN
NC score	0.045447 (rank : 296)	θ value	8.99809 (rank : 461)
Query Neighborhood Hits	474	Target Neighborhood Hits	1644	Shared Neighborhood Hits	152
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

OGFR_MOUSE
NC score	0.045045 (rank : 297)	θ value	4.03905 (rank : 362)
Query Neighborhood Hits	474	Target Neighborhood Hits	584	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

NU214_HUMAN
NC score	0.043997 (rank : 298)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	474	Target Neighborhood Hits	657	Shared Neighborhood Hits	75
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MAP1B_HUMAN
NC score	0.042956 (rank : 299)	θ value	8.99809 (rank : 460)
Query Neighborhood Hits	474	Target Neighborhood Hits	903	Shared Neighborhood Hits	92
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

BLNK_HUMAN
NC score	0.042744 (rank : 300)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	474	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

RERE_HUMAN
NC score	0.042727 (rank : 301)	θ value	5.27518 (rank : 395)
Query Neighborhood Hits	474	Target Neighborhood Hits	779	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SFRIP_HUMAN
NC score	0.042459 (rank : 302)	θ value	4.03905 (rank : 368)
Query Neighborhood Hits	474	Target Neighborhood Hits	530	Shared Neighborhood Hits	73
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SPTA3_MOUSE
NC score	0.042238 (rank : 303)	θ value	5.27518 (rank : 401)
Query Neighborhood Hits	474	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

TP53B_MOUSE
NC score	0.041681 (rank : 304)	θ value	3.0926 (rank : 335)
Query Neighborhood Hits	474	Target Neighborhood Hits	644	Shared Neighborhood Hits	91
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MILK1_HUMAN
NC score	0.041092 (rank : 305)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	474	Target Neighborhood Hits	427	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

GSCR1_HUMAN
NC score	0.040561 (rank : 306)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	474	Target Neighborhood Hits	674	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

LR37A_HUMAN
NC score	0.040523 (rank : 307)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	474	Target Neighborhood Hits	720	Shared Neighborhood Hits	97
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

EFS_MOUSE
NC score	0.039986 (rank : 308)	θ value	6.88961 (rank : 423)
Query Neighborhood Hits	474	Target Neighborhood Hits	389	Shared Neighborhood Hits	60
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

BCAR1_HUMAN
NC score	0.039832 (rank : 309)	θ value	6.88961 (rank : 418)
Query Neighborhood Hits	474	Target Neighborhood Hits	554	Shared Neighborhood Hits	94
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MAST2_HUMAN
NC score	0.039723 (rank : 310)	θ value	4.03905 (rank : 358)
Query Neighborhood Hits	474	Target Neighborhood Hits	1189	Shared Neighborhood Hits	155
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

EFHB_MOUSE
NC score	0.039499 (rank : 311)	θ value	0.21417 (rank : 180)
Query Neighborhood Hits	474	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

GNDS_HUMAN
NC score	0.039304 (rank : 312)	θ value	0.0563607 (rank : 151)
Query Neighborhood Hits	474	Target Neighborhood Hits	201	Shared Neighborhood Hits	34
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

WASF3_HUMAN
NC score	0.038446 (rank : 313)	θ value	0.163984 (rank : 177)
Query Neighborhood Hits	474	Target Neighborhood Hits	204	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

MAST2_MOUSE
NC score	0.038061 (rank : 314)	θ value	1.81305 (rank : 276)
Query Neighborhood Hits	474	Target Neighborhood Hits	1110	Shared Neighborhood Hits	148
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

BRD4_MOUSE
NC score	0.037961 (rank : 315)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	474	Target Neighborhood Hits	845	Shared Neighborhood Hits	112
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

K1210_HUMAN
NC score	0.037934 (rank : 316)	θ value	8.99809 (rank : 457)
Query Neighborhood Hits	474	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MLL3_MOUSE
NC score	0.037447 (rank : 317)	θ value	3.0926 (rank : 327)
Query Neighborhood Hits	474	Target Neighborhood Hits	1399	Shared Neighborhood Hits	130
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

AFF1_MOUSE
NC score	0.037422 (rank : 318)	θ value	6.88961 (rank : 415)
Query Neighborhood Hits	474	Target Neighborhood Hits	351	Shared Neighborhood Hits	68
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

LCP2_MOUSE
NC score	0.036232 (rank : 319)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	474	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MINT_HUMAN
NC score	0.036227 (rank : 320)	θ value	5.27518 (rank : 388)
Query Neighborhood Hits	474	Target Neighborhood Hits	1291	Shared Neighborhood Hits	136
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC2_HUMAN
NC score	0.035606 (rank : 321)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	474	Target Neighborhood Hits	906	Shared Neighborhood Hits	84
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PKHA5_HUMAN
NC score	0.034833 (rank : 322)	θ value	1.06291 (rank : 242)
Query Neighborhood Hits	474	Target Neighborhood Hits	455	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

GGN_MOUSE
NC score	0.034812 (rank : 323)	θ value	4.03905 (rank : 351)
Query Neighborhood Hits	474	Target Neighborhood Hits	311	Shared Neighborhood Hits	49
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

EFS_HUMAN
NC score	0.034559 (rank : 324)	θ value	6.88961 (rank : 422)
Query Neighborhood Hits	474	Target Neighborhood Hits	348	Shared Neighborhood Hits	48
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

HNRL1_MOUSE
NC score	0.034043 (rank : 325)	θ value	2.36792 (rank : 298)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

NCOR1_MOUSE
NC score	0.033950 (rank : 326)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	474	Target Neighborhood Hits	521	Shared Neighborhood Hits	75
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

RC3H1_HUMAN
NC score	0.033880 (rank : 327)	θ value	0.813845 (rank : 233)
Query Neighborhood Hits	474	Target Neighborhood Hits	433	Shared Neighborhood Hits	55
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

MAST1_MOUSE
NC score	0.033395 (rank : 328)	θ value	4.03905 (rank : 357)
Query Neighborhood Hits	474	Target Neighborhood Hits	1123	Shared Neighborhood Hits	138
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NFH_HUMAN
NC score	0.033358 (rank : 329)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	474	Target Neighborhood Hits	1242	Shared Neighborhood Hits	113
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

YETS2_HUMAN
NC score	0.033291 (rank : 330)	θ value	0.163984 (rank : 178)
Query Neighborhood Hits	474	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

PHAR2_HUMAN
NC score	0.033109 (rank : 331)	θ value	1.81305 (rank : 285)
Query Neighborhood Hits	474	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

TJAP1_MOUSE
NC score	0.032955 (rank : 332)	θ value	0.62314 (rank : 220)
Query Neighborhood Hits	474	Target Neighborhood Hits	295	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

LIMK2_MOUSE
NC score	0.032825 (rank : 333)	θ value	0.00509761 (rank : 114)
Query Neighborhood Hits	474	Target Neighborhood Hits	998	Shared Neighborhood Hits	75
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MAST1_HUMAN
NC score	0.032610 (rank : 334)	θ value	5.27518 (rank : 387)
Query Neighborhood Hits	474	Target Neighborhood Hits	1146	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

RANB3_MOUSE
NC score	0.032562 (rank : 335)	θ value	0.813845 (rank : 231)
Query Neighborhood Hits	474	Target Neighborhood Hits	123	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SAPS1_HUMAN
NC score	0.032467 (rank : 336)	θ value	3.0926 (rank : 331)
Query Neighborhood Hits	474	Target Neighborhood Hits	704	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SVIL_HUMAN
NC score	0.032409 (rank : 337)	θ value	2.36792 (rank : 309)
Query Neighborhood Hits	474	Target Neighborhood Hits	232	Shared Neighborhood Hits	41
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

BCAR1_MOUSE
NC score	0.032275 (rank : 338)	θ value	6.88961 (rank : 419)
Query Neighborhood Hits	474	Target Neighborhood Hits	438	Shared Neighborhood Hits	79
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

ETV5_MOUSE
NC score	0.032227 (rank : 339)	θ value	0.0961366 (rank : 160)
Query Neighborhood Hits	474	Target Neighborhood Hits	328	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

CSF1_MOUSE
NC score	0.032039 (rank : 340)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	474	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

TROAP_HUMAN
NC score	0.031971 (rank : 341)	θ value	5.27518 (rank : 413)
Query Neighborhood Hits	474	Target Neighborhood Hits	258	Shared Neighborhood Hits	55
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

LRC8E_MOUSE
NC score	0.031732 (rank : 342)	θ value	2.36792 (rank : 301)
Query Neighborhood Hits	474	Target Neighborhood Hits	256	Shared Neighborhood Hits	10
SwissProt Accessions	Q66JT1	Gene names	Lrrc8e
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

IDD_MOUSE
NC score	0.031632 (rank : 343)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	474	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

NBR1_HUMAN
NC score	0.031084 (rank : 344)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	474	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

SFPQ_MOUSE
NC score	0.031073 (rank : 345)	θ value	0.62314 (rank : 217)
Query Neighborhood Hits	474	Target Neighborhood Hits	958	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PDC6I_MOUSE
NC score	0.030895 (rank : 346)	θ value	1.06291 (rank : 240)
Query Neighborhood Hits	474	Target Neighborhood Hits	275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

GIDRP_MOUSE
NC score	0.030871 (rank : 347)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	474	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BJM3, Q3UGJ8, Q5U5U8	Gene names	Gidrp88, D19Ertd386e
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 homolog.

PAIP1_HUMAN
NC score	0.030842 (rank : 348)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	474	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

ENAM_MOUSE
NC score	0.030660 (rank : 349)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	474	Target Neighborhood Hits	229	Shared Neighborhood Hits	55
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

ASPP1_HUMAN
NC score	0.030503 (rank : 350)	θ value	1.38821 (rank : 245)
Query Neighborhood Hits	474	Target Neighborhood Hits	956	Shared Neighborhood Hits	83
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

LIMK2_HUMAN
NC score	0.030477 (rank : 351)	θ value	0.00869519 (rank : 124)
Query Neighborhood Hits	474	Target Neighborhood Hits	986	Shared Neighborhood Hits	78
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

ROBO3_HUMAN
NC score	0.029249 (rank : 352)	θ value	8.99809 (rank : 468)
Query Neighborhood Hits	474	Target Neighborhood Hits	570	Shared Neighborhood Hits	44
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

LRC8E_HUMAN
NC score	0.029129 (rank : 353)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	474	Target Neighborhood Hits	259	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NSJ5, Q2YDY3, Q7L236, Q8N3B0, Q9H5H8	Gene names	LRRC8E
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

SYN3_MOUSE
NC score	0.028658 (rank : 354)	θ value	2.36792 (rank : 310)
Query Neighborhood Hits	474	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

MYPN_MOUSE
NC score	0.028500 (rank : 355)	θ value	1.81305 (rank : 277)
Query Neighborhood Hits	474	Target Neighborhood Hits	421	Shared Neighborhood Hits	36
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

WASF3_MOUSE
NC score	0.028353 (rank : 356)	θ value	3.0926 (rank : 337)
Query Neighborhood Hits	474	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WWP2_HUMAN
NC score	0.028209 (rank : 357)	θ value	2.36792 (rank : 313)
Query Neighborhood Hits	474	Target Neighborhood Hits	177	Shared Neighborhood Hits	33
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

GAK2_HUMAN
NC score	0.027986 (rank : 358)	θ value	1.38821 (rank : 251)
Query Neighborhood Hits	474	Target Neighborhood Hits	406	Shared Neighborhood Hits	60
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MUCDL_MOUSE
NC score	0.027927 (rank : 359)	θ value	4.03905 (rank : 360)
Query Neighborhood Hits	474	Target Neighborhood Hits	461	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RNC_HUMAN
NC score	0.027805 (rank : 360)	θ value	2.36792 (rank : 307)
Query Neighborhood Hits	474	Target Neighborhood Hits	176	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

ANK3_HUMAN
NC score	0.027750 (rank : 361)	θ value	0.0961366 (rank : 157)
Query Neighborhood Hits	474	Target Neighborhood Hits	853	Shared Neighborhood Hits	76
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CD2AP_MOUSE
NC score	0.027637 (rank : 362)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	474	Target Neighborhood Hits	336	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

K1683_HUMAN
NC score	0.027572 (rank : 363)	θ value	8.99809 (rank : 458)
Query Neighborhood Hits	474	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

APC_MOUSE
NC score	0.027478 (rank : 364)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	474	Target Neighborhood Hits	441	Shared Neighborhood Hits	52
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

AFF4_HUMAN
NC score	0.027422 (rank : 365)	θ value	6.88961 (rank : 416)
Query Neighborhood Hits	474	Target Neighborhood Hits	611	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ZIM10_HUMAN
NC score	0.027315 (rank : 366)	θ value	1.06291 (rank : 244)
Query Neighborhood Hits	474	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ASXL1_MOUSE
NC score	0.027176 (rank : 367)	θ value	1.38821 (rank : 246)
Query Neighborhood Hits	474	Target Neighborhood Hits	182	Shared Neighborhood Hits	35
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

GAK5_HUMAN
NC score	0.027088 (rank : 368)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	474	Target Neighborhood Hits	429	Shared Neighborhood Hits	69
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

K1802_HUMAN
NC score	0.026931 (rank : 369)	θ value	8.99809 (rank : 459)
Query Neighborhood Hits	474	Target Neighborhood Hits	1378	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

GAK12_HUMAN
NC score	0.026912 (rank : 370)	θ value	1.81305 (rank : 272)
Query Neighborhood Hits	474	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAS1_HUMAN
NC score	0.026455 (rank : 371)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	474	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

K0319_MOUSE
NC score	0.026129 (rank : 372)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	474	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

US6NL_HUMAN
NC score	0.026127 (rank : 373)	θ value	3.0926 (rank : 336)
Query Neighborhood Hits	474	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

HNRL1_HUMAN
NC score	0.026069 (rank : 374)	θ value	4.03905 (rank : 353)
Query Neighborhood Hits	474	Target Neighborhood Hits	173	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

ANK1_HUMAN
NC score	0.025879 (rank : 375)	θ value	0.0431538 (rank : 147)
Query Neighborhood Hits	474	Target Neighborhood Hits	416	Shared Neighborhood Hits	24
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

SSXT_HUMAN
NC score	0.025414 (rank : 376)	θ value	5.27518 (rank : 403)
Query Neighborhood Hits	474	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

MYPN_HUMAN
NC score	0.025381 (rank : 377)	θ value	2.36792 (rank : 304)
Query Neighborhood Hits	474	Target Neighborhood Hits	418	Shared Neighborhood Hits	42
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

FILA_HUMAN
NC score	0.025082 (rank : 378)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	474	Target Neighborhood Hits	685	Shared Neighborhood Hits	55
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

ZIM10_MOUSE
NC score	0.025052 (rank : 379)	θ value	1.81305 (rank : 291)
Query Neighborhood Hits	474	Target Neighborhood Hits	430	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

PKHA2_HUMAN
NC score	0.024684 (rank : 380)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	474	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

HELZ_HUMAN
NC score	0.024619 (rank : 381)	θ value	0.279714 (rank : 184)
Query Neighborhood Hits	474	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

ANK1_MOUSE
NC score	0.024491 (rank : 382)	θ value	0.125558 (rank : 163)
Query Neighborhood Hits	474	Target Neighborhood Hits	430	Shared Neighborhood Hits	25
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

MYST3_HUMAN
NC score	0.023863 (rank : 383)	θ value	4.03905 (rank : 361)
Query Neighborhood Hits	474	Target Neighborhood Hits	772	Shared Neighborhood Hits	76
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
NC score	0.023618 (rank : 384)	θ value	5.27518 (rank : 389)
Query Neighborhood Hits	474	Target Neighborhood Hits	688	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

CD2AP_HUMAN
NC score	0.023548 (rank : 385)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	474	Target Neighborhood Hits	315	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SYN3_HUMAN
NC score	0.023435 (rank : 386)	θ value	5.27518 (rank : 406)
Query Neighborhood Hits	474	Target Neighborhood Hits	203	Shared Neighborhood Hits	47
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

GAK4_HUMAN
NC score	0.023417 (rank : 387)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	474	Target Neighborhood Hits	415	Shared Neighborhood Hits	60
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

FRM4B_MOUSE
NC score	0.023395 (rank : 388)	θ value	2.36792 (rank : 296)
Query Neighborhood Hits	474	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

GAK10_HUMAN
NC score	0.023369 (rank : 389)	θ value	4.03905 (rank : 349)
Query Neighborhood Hits	474	Target Neighborhood Hits	289	Shared Neighborhood Hits	51
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.023343 (rank : 390)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	474	Target Neighborhood Hits	409	Shared Neighborhood Hits	60
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

WDR46_MOUSE
NC score	0.023017 (rank : 391)	θ value	1.81305 (rank : 290)
Query Neighborhood Hits	474	Target Neighborhood Hits	243	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

HGS_MOUSE
NC score	0.022996 (rank : 392)	θ value	2.36792 (rank : 297)
Query Neighborhood Hits	474	Target Neighborhood Hits	589	Shared Neighborhood Hits	72
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

BAZ2A_HUMAN
NC score	0.022791 (rank : 393)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	474	Target Neighborhood Hits	780	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

IF4B_HUMAN
NC score	0.022579 (rank : 394)	θ value	4.03905 (rank : 354)
Query Neighborhood Hits	474	Target Neighborhood Hits	417	Shared Neighborhood Hits	50
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MYO15_MOUSE
NC score	0.022448 (rank : 395)	θ value	0.0113563 (rank : 129)
Query Neighborhood Hits	474	Target Neighborhood Hits	467	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ZAN_HUMAN
NC score	0.022247 (rank : 396)	θ value	4.03905 (rank : 373)
Query Neighborhood Hits	474	Target Neighborhood Hits	679	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TITIN_HUMAN
NC score	0.022041 (rank : 397)	θ value	5.27518 (rank : 412)
Query Neighborhood Hits	474	Target Neighborhood Hits	2923	Shared Neighborhood Hits	181
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

REXO1_MOUSE
NC score	0.021923 (rank : 398)	θ value	1.81305 (rank : 286)
Query Neighborhood Hits	474	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

CDC73_HUMAN
NC score	0.021724 (rank : 399)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	474	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P1J9, Q6PK51, Q96A07, Q9H245, Q9H5L7	Gene names	CDC73, C1orf28, HRPT2
Domain Architecture	No domain graphic available
Description	Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein).

CDC73_MOUSE
NC score	0.021724 (rank : 400)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	474	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q8JZM7	Gene names	Cdc73
Domain Architecture	No domain graphic available
Description	Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein homolog).

GAK1_HUMAN
NC score	0.021662 (rank : 401)	θ value	5.27518 (rank : 382)
Query Neighborhood Hits	474	Target Neighborhood Hits	268	Shared Neighborhood Hits	46
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

S18L1_HUMAN
NC score	0.021287 (rank : 402)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	474	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	O75177, Q5JXJ3, Q8NE69, Q9BR55, Q9H4K6	Gene names	SS18L1, KIAA0693
Domain Architecture
Description	SS18-like protein 1 (SYT homolog 1).

SYN2_MOUSE
NC score	0.021266 (rank : 403)	θ value	5.27518 (rank : 405)
Query Neighborhood Hits	474	Target Neighborhood Hits	183	Shared Neighborhood Hits	44
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

RTN4_HUMAN
NC score	0.021263 (rank : 404)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	474	Target Neighborhood Hits	357	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TEX2_MOUSE
NC score	0.021069 (rank : 405)	θ value	5.27518 (rank : 409)
Query Neighborhood Hits	474	Target Neighborhood Hits	121	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ICB1_MOUSE
NC score	0.020682 (rank : 406)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	474	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

CBL_HUMAN
NC score	0.020619 (rank : 407)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	474	Target Neighborhood Hits	353	Shared Neighborhood Hits	42
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

SRBS1_MOUSE
NC score	0.020467 (rank : 408)	θ value	3.0926 (rank : 333)
Query Neighborhood Hits	474	Target Neighborhood Hits	409	Shared Neighborhood Hits	58
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

5NT1B_MOUSE
NC score	0.020185 (rank : 409)	θ value	2.36792 (rank : 292)
Query Neighborhood Hits	474	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

AMOL1_MOUSE
NC score	0.019910 (rank : 410)	θ value	0.279714 (rank : 183)
Query Neighborhood Hits	474	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

NUFP1_MOUSE
NC score	0.019550 (rank : 411)	θ value	1.38821 (rank : 262)
Query Neighborhood Hits	474	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

HGS_HUMAN
NC score	0.019533 (rank : 412)	θ value	5.27518 (rank : 384)
Query Neighborhood Hits	474	Target Neighborhood Hits	517	Shared Neighborhood Hits	60
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

PARM1_HUMAN
NC score	0.019277 (rank : 413)	θ value	8.99809 (rank : 466)
Query Neighborhood Hits	474	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PHLA1_MOUSE
NC score	0.019027 (rank : 414)	θ value	5.27518 (rank : 391)
Query Neighborhood Hits	474	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

CNTRB_MOUSE
NC score	0.019005 (rank : 415)	θ value	2.36792 (rank : 295)
Query Neighborhood Hits	474	Target Neighborhood Hits	1029	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

PRGC1_MOUSE
NC score	0.018832 (rank : 416)	θ value	3.0926 (rank : 329)
Query Neighborhood Hits	474	Target Neighborhood Hits	238	Shared Neighborhood Hits	30
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

AIM1_HUMAN
NC score	0.018775 (rank : 417)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	474	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

GAK8_HUMAN
NC score	0.018346 (rank : 418)	θ value	4.03905 (rank : 350)
Query Neighborhood Hits	474	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TEX2_HUMAN
NC score	0.018301 (rank : 419)	θ value	5.27518 (rank : 408)
Query Neighborhood Hits	474	Target Neighborhood Hits	106	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

SPEG_MOUSE
NC score	0.018127 (rank : 420)	θ value	5.27518 (rank : 400)
Query Neighborhood Hits	474	Target Neighborhood Hits	1959	Shared Neighborhood Hits	163
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MTG8_MOUSE
NC score	0.017840 (rank : 421)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	474	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

LBXCO_HUMAN
NC score	0.017657 (rank : 422)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	474	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

MTG8_HUMAN
NC score	0.017556 (rank : 423)	θ value	1.38821 (rank : 258)
Query Neighborhood Hits	474	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

CT174_HUMAN
NC score	0.017384 (rank : 424)	θ value	6.88961 (rank : 420)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

FA13C_HUMAN
NC score	0.016831 (rank : 425)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	474	Target Neighborhood Hits	94	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

RCOR2_HUMAN
NC score	0.016420 (rank : 426)	θ value	3.0926 (rank : 330)
Query Neighborhood Hits	474	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

TREF1_HUMAN
NC score	0.016284 (rank : 427)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	474	Target Neighborhood Hits	651	Shared Neighborhood Hits	44
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

NEO1_MOUSE
NC score	0.016154 (rank : 428)	θ value	2.36792 (rank : 305)
Query Neighborhood Hits	474	Target Neighborhood Hits	523	Shared Neighborhood Hits	24
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NEO1_HUMAN
NC score	0.016016 (rank : 429)	θ value	1.38821 (rank : 261)
Query Neighborhood Hits	474	Target Neighborhood Hits	530	Shared Neighborhood Hits	25
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

B4GN4_HUMAN
NC score	0.015547 (rank : 430)	θ value	1.81305 (rank : 268)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	27
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

ATBF1_HUMAN
NC score	0.015141 (rank : 431)	θ value	1.38821 (rank : 247)
Query Neighborhood Hits	474	Target Neighborhood Hits	1547	Shared Neighborhood Hits	99
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TOPB1_MOUSE
NC score	0.015059 (rank : 432)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	474	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

SRC8_HUMAN
NC score	0.015029 (rank : 433)	θ value	3.0926 (rank : 334)
Query Neighborhood Hits	474	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SHD_HUMAN
NC score	0.015001 (rank : 434)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	474	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SCEL_HUMAN
NC score	0.014970 (rank : 435)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	474	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SRC8_MOUSE
NC score	0.014918 (rank : 436)	θ value	2.36792 (rank : 308)
Query Neighborhood Hits	474	Target Neighborhood Hits	292	Shared Neighborhood Hits	25
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

STAT6_MOUSE
NC score	0.014854 (rank : 437)	θ value	1.81305 (rank : 289)
Query Neighborhood Hits	474	Target Neighborhood Hits	78	Shared Neighborhood Hits	16
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

SH2D3_MOUSE
NC score	0.014709 (rank : 438)	θ value	0.813845 (rank : 234)
Query Neighborhood Hits	474	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

MBP_MOUSE
NC score	0.014155 (rank : 439)	θ value	4.03905 (rank : 359)
Query Neighborhood Hits	474	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P04370, Q01585, Q03139, Q03176, Q61836, Q61837, Q99KE4, Q9QWP1	Gene names	Mbp, Shi
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein).

ETV5_HUMAN
NC score	0.013952 (rank : 440)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	474	Target Neighborhood Hits	181	Shared Neighborhood Hits	33
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

RAI14_MOUSE
NC score	0.013782 (rank : 441)	θ value	5.27518 (rank : 394)
Query Neighborhood Hits	474	Target Neighborhood Hits	1505	Shared Neighborhood Hits	74
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RBP56_HUMAN
NC score	0.013711 (rank : 442)	θ value	4.03905 (rank : 365)
Query Neighborhood Hits	474	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q92804, Q92751	Gene names	TAF15, RBP56, TAF2N
Domain Architecture
Description	TATA-binding protein-associated factor 2N (RNA-binding protein 56) (TAFII68) (TAF(II)68).

SAFB2_HUMAN
NC score	0.013695 (rank : 443)	θ value	8.99809 (rank : 469)
Query Neighborhood Hits	474	Target Neighborhood Hits	720	Shared Neighborhood Hits	39
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

RD23B_MOUSE
NC score	0.013560 (rank : 444)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	474	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PML_HUMAN
NC score	0.012842 (rank : 445)	θ value	3.0926 (rank : 328)
Query Neighborhood Hits	474	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

DAB1_MOUSE
NC score	0.012689 (rank : 446)	θ value	6.88961 (rank : 421)
Query Neighborhood Hits	474	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

CTND2_MOUSE
NC score	0.012538 (rank : 447)	θ value	1.81305 (rank : 271)
Query Neighborhood Hits	474	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

TF7L1_MOUSE
NC score	0.011733 (rank : 448)	θ value	2.36792 (rank : 312)
Query Neighborhood Hits	474	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TF2L1_MOUSE
NC score	0.011711 (rank : 449)	θ value	5.27518 (rank : 411)
Query Neighborhood Hits	474	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UNW5, Q99PF2	Gene names	Tcfcp2l1, Crtr1
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1).

ERRFI_HUMAN
NC score	0.011593 (rank : 450)	θ value	6.88961 (rank : 424)
Query Neighborhood Hits	474	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

LOXL1_MOUSE
NC score	0.011464 (rank : 451)	θ value	2.36792 (rank : 300)
Query Neighborhood Hits	474	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

AAK1_HUMAN
NC score	0.011351 (rank : 452)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	474	Target Neighborhood Hits	1077	Shared Neighborhood Hits	92
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

TACC3_MOUSE
NC score	0.011234 (rank : 453)	θ value	4.03905 (rank : 370)
Query Neighborhood Hits	474	Target Neighborhood Hits	607	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

RP1L1_MOUSE
NC score	0.011232 (rank : 454)	θ value	5.27518 (rank : 396)
Query Neighborhood Hits	474	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

FRK_HUMAN
NC score	0.011146 (rank : 455)	θ value	5.27518 (rank : 381)
Query Neighborhood Hits	474	Target Neighborhood Hits	1058	Shared Neighborhood Hits	59
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

TF2L1_HUMAN
NC score	0.011122 (rank : 456)	θ value	5.27518 (rank : 410)
Query Neighborhood Hits	474	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZI6, Q4ZG43	Gene names	TFCP2L1, CRTR1, LBP9
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9).

K1024_HUMAN
NC score	0.010957 (rank : 457)	θ value	4.03905 (rank : 356)
Query Neighborhood Hits	474	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

TF7L1_HUMAN
NC score	0.010728 (rank : 458)	θ value	2.36792 (rank : 311)
Query Neighborhood Hits	474	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

CING_HUMAN
NC score	0.010690 (rank : 459)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	474	Target Neighborhood Hits	1275	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

TTC28_HUMAN
NC score	0.010048 (rank : 460)	θ value	8.99809 (rank : 472)
Query Neighborhood Hits	474	Target Neighborhood Hits	271	Shared Neighborhood Hits	35
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

CCD96_HUMAN
NC score	0.009991 (rank : 461)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	474	Target Neighborhood Hits	595	Shared Neighborhood Hits	39
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

MEF2A_HUMAN
NC score	0.009973 (rank : 462)	θ value	2.36792 (rank : 302)
Query Neighborhood Hits	474	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

FOXM1_MOUSE
NC score	0.009677 (rank : 463)	θ value	1.38821 (rank : 250)
Query Neighborhood Hits	474	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	O08696	Gene names	Foxm1, Fkh16
Domain Architecture
Description	Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).

JAD1C_HUMAN
NC score	0.009412 (rank : 464)	θ value	4.03905 (rank : 355)
Query Neighborhood Hits	474	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

NCA12_HUMAN
NC score	0.009406 (rank : 465)	θ value	8.99809 (rank : 465)
Query Neighborhood Hits	474	Target Neighborhood Hits	437	Shared Neighborhood Hits	20
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

SOCS6_MOUSE
NC score	0.009359 (rank : 466)	θ value	6.88961 (rank : 438)
Query Neighborhood Hits	474	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

NCA11_HUMAN
NC score	0.009208 (rank : 467)	θ value	8.99809 (rank : 464)
Query Neighborhood Hits	474	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

MYO1E_HUMAN
NC score	0.009128 (rank : 468)	θ value	8.99809 (rank : 463)
Query Neighborhood Hits	474	Target Neighborhood Hits	293	Shared Neighborhood Hits	36
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

CECR1_HUMAN
NC score	0.009073 (rank : 469)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	474	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZK5, Q96K41	Gene names	CECR1
Domain Architecture
Description	Cat eye syndrome critical region protein 1 precursor.

SMCA2_HUMAN
NC score	0.008916 (rank : 470)	θ value	5.27518 (rank : 399)
Query Neighborhood Hits	474	Target Neighborhood Hits	503	Shared Neighborhood Hits	45
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SRGP2_HUMAN
NC score	0.008898 (rank : 471)	θ value	5.27518 (rank : 402)
Query Neighborhood Hits	474	Target Neighborhood Hits	331	Shared Neighborhood Hits	27
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

JAD1C_MOUSE
NC score	0.008681 (rank : 472)	θ value	5.27518 (rank : 386)
Query Neighborhood Hits	474	Target Neighborhood Hits	164	Shared Neighborhood Hits	13
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

RBP2_MOUSE
NC score	0.008633 (rank : 473)	θ value	0.813845 (rank : 232)
Query Neighborhood Hits	474	Target Neighborhood Hits	232	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

ANKS1_MOUSE
NC score	0.008303 (rank : 474)	θ value	6.88961 (rank : 417)
Query Neighborhood Hits	474	Target Neighborhood Hits	453	Shared Neighborhood Hits	22
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

SDC4_HUMAN
NC score	0.008215 (rank : 475)	θ value	6.88961 (rank : 437)
Query Neighborhood Hits	474	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P31431, O00773, Q16833	Gene names	SDC4
Domain Architecture
Description	Syndecan-4 precursor (SYND4) (Amphiglycan) (Ryudocan core protein).

TFE2_MOUSE
NC score	0.008211 (rank : 476)	θ value	4.03905 (rank : 371)
Query Neighborhood Hits	474	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

BSPRY_MOUSE
NC score	0.007998 (rank : 477)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	474	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

DYHC_MOUSE
NC score	0.007955 (rank : 478)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	474	Target Neighborhood Hits	729	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.007950 (rank : 479)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	474	Target Neighborhood Hits	733	Shared Neighborhood Hits	30
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

SACS_HUMAN
NC score	0.007633 (rank : 480)	θ value	5.27518 (rank : 397)
Query Neighborhood Hits	474	Target Neighborhood Hits	128	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

CHD8_HUMAN
NC score	0.007311 (rank : 481)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	474	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

SCML2_HUMAN
NC score	0.007157 (rank : 482)	θ value	6.88961 (rank : 436)
Query Neighborhood Hits	474	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQR0, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5	Gene names	SCML2
Domain Architecture
Description	Sex comb on midleg-like protein 2.

CAC1B_MOUSE
NC score	0.006814 (rank : 483)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	474	Target Neighborhood Hits	351	Shared Neighborhood Hits	35
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PRDM8_HUMAN
NC score	0.006809 (rank : 484)	θ value	5.27518 (rank : 392)
Query Neighborhood Hits	474	Target Neighborhood Hits	591	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQV8, Q6IQ36	Gene names	PRDM8, PFM5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

UBP8_HUMAN
NC score	0.006771 (rank : 485)	θ value	4.03905 (rank : 372)
Query Neighborhood Hits	474	Target Neighborhood Hits	751	Shared Neighborhood Hits	52
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

PEG3_MOUSE
NC score	0.006682 (rank : 486)	θ value	0.0736092 (rank : 155)
Query Neighborhood Hits	474	Target Neighborhood Hits	1101	Shared Neighborhood Hits	58
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

ZFAN5_MOUSE
NC score	0.006321 (rank : 487)	θ value	8.99809 (rank : 473)
Query Neighborhood Hits	474	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

SIM2_MOUSE
NC score	0.006296 (rank : 488)	θ value	3.0926 (rank : 332)
Query Neighborhood Hits	474	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SYT6_HUMAN
NC score	0.005788 (rank : 489)	θ value	8.99809 (rank : 471)
Query Neighborhood Hits	474	Target Neighborhood Hits	138	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

HXA3_HUMAN
NC score	0.005733 (rank : 490)	θ value	1.38821 (rank : 253)
Query Neighborhood Hits	474	Target Neighborhood Hits	535	Shared Neighborhood Hits	47
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

AMPN_MOUSE
NC score	0.005688 (rank : 491)	θ value	2.36792 (rank : 293)
Query Neighborhood Hits	474	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P97449, Q91YH8, Q99K63	Gene names	Anpep, Lap-1, Lap1
Domain Architecture
Description	Aminopeptidase N (EC 3.4.11.2) (mAPN) (Alanyl aminopeptidase) (Microsomal aminopeptidase) (Aminopeptidase M) (Membrane protein p161) (CD13 antigen).

CD6_MOUSE
NC score	0.005514 (rank : 492)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	474	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

PP2CD_HUMAN
NC score	0.005302 (rank : 493)	θ value	8.99809 (rank : 467)
Query Neighborhood Hits	474	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	O15297	Gene names	PPM1D, WIP1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

SMAD5_MOUSE
NC score	0.004708 (rank : 494)	θ value	5.27518 (rank : 398)
Query Neighborhood Hits	474	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

M4K4_MOUSE
NC score	0.004563 (rank : 495)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	474	Target Neighborhood Hits	1560	Shared Neighborhood Hits	66
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CAC1B_HUMAN
NC score	0.004414 (rank : 496)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	474	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FOXN4_MOUSE
NC score	0.004398 (rank : 497)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	474	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

MMP15_MOUSE
NC score	0.003721 (rank : 498)	θ value	2.36792 (rank : 303)
Query Neighborhood Hits	474	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

HERC2_MOUSE
NC score	0.003082 (rank : 499)	θ value	6.88961 (rank : 426)
Query Neighborhood Hits	474	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

GP124_HUMAN
NC score	0.003024 (rank : 500)	θ value	4.03905 (rank : 352)
Query Neighborhood Hits	474	Target Neighborhood Hits	304	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

LIRB4_HUMAN
NC score	0.002989 (rank : 501)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	474	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

GP124_MOUSE
NC score	0.002983 (rank : 502)	θ value	5.27518 (rank : 383)
Query Neighborhood Hits	474	Target Neighborhood Hits	423	Shared Neighborhood Hits	18
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CEP57_MOUSE
NC score	0.002839 (rank : 503)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	474	Target Neighborhood Hits	580	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

HIPK1_MOUSE
NC score	0.002493 (rank : 504)	θ value	1.81305 (rank : 273)
Query Neighborhood Hits	474	Target Neighborhood Hits	838	Shared Neighborhood Hits	33
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

TLE3_HUMAN
NC score	0.002479 (rank : 505)	θ value	6.88961 (rank : 439)
Query Neighborhood Hits	474	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

HIPK1_HUMAN
NC score	0.002343 (rank : 506)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	474	Target Neighborhood Hits	843	Shared Neighborhood Hits	34
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

LTBP4_MOUSE
NC score	0.002254 (rank : 507)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	474	Target Neighborhood Hits	607	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TBX3_MOUSE
NC score	0.002226 (rank : 508)	θ value	5.27518 (rank : 407)
Query Neighborhood Hits	474	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

HDAC5_HUMAN
NC score	0.002118 (rank : 509)	θ value	8.99809 (rank : 456)
Query Neighborhood Hits	474	Target Neighborhood Hits	353	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

BCR_HUMAN
NC score	0.001662 (rank : 510)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	474	Target Neighborhood Hits	204	Shared Neighborhood Hits	12
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

ZN217_HUMAN
NC score	0.001211 (rank : 511)	θ value	0.62314 (rank : 222)
Query Neighborhood Hits	474	Target Neighborhood Hits	905	Shared Neighborhood Hits	65
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

HNF3G_HUMAN
NC score	0.001077 (rank : 512)	θ value	6.88961 (rank : 427)
Query Neighborhood Hits	474	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	P55318, Q9UMW9	Gene names	FOXA3, HNF3G, TCF3G
Domain Architecture
Description	Hepatocyte nuclear factor 3-gamma (HNF-3G) (Forkhead box protein A3) (Fork head-related protein FKH H3).

ZN438_HUMAN
NC score	0.000964 (rank : 513)	θ value	6.88961 (rank : 440)
Query Neighborhood Hits	474	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

PAK6_HUMAN
NC score	0.000517 (rank : 514)	θ value	2.36792 (rank : 306)
Query Neighborhood Hits	474	Target Neighborhood Hits	915	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

M3K9_HUMAN
NC score	0.000374 (rank : 515)	θ value	1.81305 (rank : 275)
Query Neighborhood Hits	474	Target Neighborhood Hits	1123	Shared Neighborhood Hits	57
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NEK1_MOUSE
NC score	-0.000365 (rank : 516)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	474	Target Neighborhood Hits	1311	Shared Neighborhood Hits	56
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SPA3A_MOUSE
NC score	-0.000386 (rank : 517)	θ value	4.03905 (rank : 369)
Query Neighborhood Hits	474	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P4P1, Q9D490	Gene names	Serpina3a
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3A precursor (Serpin A3A).

ZBT38_HUMAN
NC score	-0.001231 (rank : 518)	θ value	0.62314 (rank : 221)
Query Neighborhood Hits	474	Target Neighborhood Hits	885	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

MLTK_MOUSE
NC score	-0.001233 (rank : 519)	θ value	1.06291 (rank : 239)
Query Neighborhood Hits	474	Target Neighborhood Hits	874	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

HXC4_MOUSE
NC score	-0.001442 (rank : 520)	θ value	5.27518 (rank : 385)
Query Neighborhood Hits	474	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

HXC4_HUMAN
NC score	-0.001538 (rank : 521)	θ value	6.88961 (rank : 428)
Query Neighborhood Hits	474	Target Neighborhood Hits	361	Shared Neighborhood Hits	10
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

1C16_HUMAN
NC score	-0.003986 (rank : 522)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	474	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q29960, O78091, O78202, Q29862, Q29959, Q9MY74, Q9MYI3, Q9TNZ8	Gene names	HLA-C, HLAC
Domain Architecture
Description	HLA class I histocompatibility antigen, Cw-16 alpha chain precursor (MHC class I antigen Cw*16).

BCL6_HUMAN
NC score	-0.004673 (rank : 523)	θ value	1.81305 (rank : 269)
Query Neighborhood Hits	474	Target Neighborhood Hits	922	Shared Neighborhood Hits	40
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZN509_MOUSE
NC score	-0.004682 (rank : 524)	θ value	0.813845 (rank : 238)
Query Neighborhood Hits	474	Target Neighborhood Hits	990	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

EGR2_MOUSE
NC score	-0.004707 (rank : 525)	θ value	1.38821 (rank : 249)
Query Neighborhood Hits	474	Target Neighborhood Hits	745	Shared Neighborhood Hits	23
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

EVI1_HUMAN
NC score	-0.005511 (rank : 526)	θ value	6.88961 (rank : 425)
Query Neighborhood Hits	474	Target Neighborhood Hits	924	Shared Neighborhood Hits	39
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

ZXDA_HUMAN
NC score	-0.007002 (rank : 527)	θ value	5.27518 (rank : 414)
Query Neighborhood Hits	474	Target Neighborhood Hits	750	Shared Neighborhood Hits	18
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

ZN394_HUMAN
NC score	-0.007082 (rank : 528)	θ value	8.99809 (rank : 474)
Query Neighborhood Hits	474	Target Neighborhood Hits	752	Shared Neighborhood Hits	20
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.