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Network neighborhood for query Sequence : SVIL_HUMAN

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SVIL_HUMAN
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SVIL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	232	Target Neighborhood Hits	232	Shared Neighborhood Hits	232
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SVIL_MOUSE
θ value	0 (rank : 2)	NC score	0.929208 (rank : 2)
Query Neighborhood Hits	232	Target Neighborhood Hits	439	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

AVIL_HUMAN
θ value	7.03111e-45 (rank : 3)	NC score	0.767929 (rank : 4)
Query Neighborhood Hits	232	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	O75366	Gene names	AVIL
Domain Architecture
Description	Advillin (p92).

AVIL_MOUSE
θ value	1.56636e-44 (rank : 4)	NC score	0.768167 (rank : 3)
Query Neighborhood Hits	232	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	O88398, O70466	Gene names	Avil, Advil
Domain Architecture
Description	Advillin (p92) (Actin-binding protein DOC6).

VILI_MOUSE
θ value	3.48949e-44 (rank : 5)	NC score	0.766913 (rank : 6)
Query Neighborhood Hits	232	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q62468, Q91WH4	Gene names	Vil1, Vil
Domain Architecture
Description	Villin-1.

VILI_HUMAN
θ value	7.77379e-44 (rank : 6)	NC score	0.767017 (rank : 5)
Query Neighborhood Hits	232	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P09327	Gene names	VIL1, VIL
Domain Architecture
Description	Villin-1.

VILL_HUMAN
θ value	7.52953e-39 (rank : 7)	NC score	0.763939 (rank : 7)
Query Neighborhood Hits	232	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	O15195, Q9BT80, Q9BWH7	Gene names	VILL
Domain Architecture
Description	Villin-like protein.

GELS_MOUSE
θ value	8.06329e-33 (rank : 8)	NC score	0.735821 (rank : 10)
Query Neighborhood Hits	232	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	P13020, Q3UPB1, Q8R590	Gene names	Gsn, Gsb
Domain Architecture
Description	Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin).

GELS_HUMAN
θ value	1.0531e-32 (rank : 9)	NC score	0.736303 (rank : 9)
Query Neighborhood Hits	232	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	P06396, Q8WVV7	Gene names	GSN
Domain Architecture
Description	Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL).

VILL_MOUSE
θ value	8.91499e-32 (rank : 10)	NC score	0.752427 (rank : 8)
Query Neighborhood Hits	232	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q91YD6, P97809, Q8BIS5, Q8R211, Q8VDI8	Gene names	Vill, Villp
Domain Architecture	No domain graphic available
Description	Villin-like protein (EF-6).

ADSV_HUMAN
θ value	5.77852e-31 (rank : 11)	NC score	0.735099 (rank : 11)
Query Neighborhood Hits	232	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6U3, Q8NBZ6, Q8WU97, Q96JC7, Q96PY2	Gene names	SCIN, KIAA1905
Domain Architecture
Description	Adseverin (Scinderin).

ADSV_MOUSE
θ value	6.38894e-30 (rank : 12)	NC score	0.733114 (rank : 12)
Query Neighborhood Hits	232	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	Q60604, O08988, O08990	Gene names	Scin
Domain Architecture
Description	Adseverin (Scinderin) (Gelsolin-like protein).

FLII_HUMAN
θ value	1.09232e-21 (rank : 13)	NC score	0.409615 (rank : 16)
Query Neighborhood Hits	232	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

FLII_MOUSE
θ value	7.0802e-21 (rank : 14)	NC score	0.412366 (rank : 15)
Query Neighborhood Hits	232	Target Neighborhood Hits	304	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJ28, Q8K095, Q8VI44	Gene names	Flii, Fli1, Fliih
Domain Architecture	No domain graphic available
Description	Protein flightless-1 homolog.

CAPG_HUMAN
θ value	2.13673e-09 (rank : 15)	NC score	0.668873 (rank : 13)
Query Neighborhood Hits	232	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	P40121	Gene names	CAPG, MCP
Domain Architecture
Description	Macrophage capping protein (Actin-regulatory protein CAP-G).

CAPG_MOUSE
θ value	8.11959e-09 (rank : 16)	NC score	0.660029 (rank : 14)
Query Neighborhood Hits	232	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P24452	Gene names	Capg, Mbh1
Domain Architecture
Description	Macrophage capping protein (Myc basic motif homolog 1) (Actin-capping protein GCAP39).

SRRM2_MOUSE
θ value	0.000121331 (rank : 17)	NC score	0.139478 (rank : 21)
Query Neighborhood Hits	232	Target Neighborhood Hits	1470	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DEMA_HUMAN
θ value	0.000461057 (rank : 18)	NC score	0.276823 (rank : 18)
Query Neighborhood Hits	232	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q08495, Q13215, Q9BRE3	Gene names	EPB49, DMT
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DEMA_MOUSE
θ value	0.000461057 (rank : 19)	NC score	0.278645 (rank : 17)
Query Neighborhood Hits	232	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

MINT_MOUSE
θ value	0.00175202 (rank : 20)	NC score	0.087202 (rank : 35)
Query Neighborhood Hits	232	Target Neighborhood Hits	1514	Shared Neighborhood Hits	102
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_MOUSE
θ value	0.00228821 (rank : 21)	NC score	0.067576 (rank : 59)
Query Neighborhood Hits	232	Target Neighborhood Hits	2247	Shared Neighborhood Hits	129
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ABLM2_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.136612 (rank : 22)
Query Neighborhood Hits	232	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

ABLM2_MOUSE
θ value	0.00390308 (rank : 23)	NC score	0.136241 (rank : 23)
Query Neighborhood Hits	232	Target Neighborhood Hits	306	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

ABLM3_HUMAN
θ value	0.00509761 (rank : 24)	NC score	0.140993 (rank : 19)
Query Neighborhood Hits	232	Target Neighborhood Hits	293	Shared Neighborhood Hits	24
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_MOUSE
θ value	0.00665767 (rank : 25)	NC score	0.139773 (rank : 20)
Query Neighborhood Hits	232	Target Neighborhood Hits	294	Shared Neighborhood Hits	22
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

BSN_MOUSE
θ value	0.00665767 (rank : 26)	NC score	0.078983 (rank : 43)
Query Neighborhood Hits	232	Target Neighborhood Hits	2057	Shared Neighborhood Hits	96
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PRP4B_MOUSE
θ value	0.00665767 (rank : 27)	NC score	0.038167 (rank : 117)
Query Neighborhood Hits	232	Target Neighborhood Hits	1040	Shared Neighborhood Hits	54
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SPEG_HUMAN
θ value	0.00869519 (rank : 28)	NC score	0.028009 (rank : 150)
Query Neighborhood Hits	232	Target Neighborhood Hits	1762	Shared Neighborhood Hits	60
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PRP4B_HUMAN
θ value	0.0148317 (rank : 29)	NC score	0.035299 (rank : 123)
Query Neighborhood Hits	232	Target Neighborhood Hits	1030	Shared Neighborhood Hits	47
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

ANK2_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.044890 (rank : 103)
Query Neighborhood Hits	232	Target Neighborhood Hits	1615	Shared Neighborhood Hits	107
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RBBP6_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.085935 (rank : 36)
Query Neighborhood Hits	232	Target Neighborhood Hits	1135	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SRRM2_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.122708 (rank : 24)
Query Neighborhood Hits	232	Target Neighborhood Hits	1296	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ACINU_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.109332 (rank : 28)
Query Neighborhood Hits	232	Target Neighborhood Hits	828	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SPEG_MOUSE
θ value	0.0330416 (rank : 34)	NC score	0.030142 (rank : 137)
Query Neighborhood Hits	232	Target Neighborhood Hits	1959	Shared Neighborhood Hits	78
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

NACAM_MOUSE
θ value	0.0431538 (rank : 35)	NC score	0.068859 (rank : 55)
Query Neighborhood Hits	232	Target Neighborhood Hits	1866	Shared Neighborhood Hits	94
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ZC313_HUMAN
θ value	0.0431538 (rank : 36)	NC score	0.083437 (rank : 38)
Query Neighborhood Hits	232	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CDCA7_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.081847 (rank : 40)
Query Neighborhood Hits	232	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D0M2, Q3TIS1, Q3U511, Q6NZE5, Q8C1A0	Gene names	Cdca7
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7.

MYPT1_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.026953 (rank : 156)
Query Neighborhood Hits	232	Target Neighborhood Hits	539	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

SETD2_HUMAN
θ value	0.0563607 (rank : 39)	NC score	0.068164 (rank : 58)
Query Neighborhood Hits	232	Target Neighborhood Hits	412	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

OXR1_MOUSE
θ value	0.0736092 (rank : 40)	NC score	0.062162 (rank : 68)
Query Neighborhood Hits	232	Target Neighborhood Hits	516	Shared Neighborhood Hits	65
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SFR17_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.115035 (rank : 25)
Query Neighborhood Hits	232	Target Neighborhood Hits	325	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

LIMD1_MOUSE
θ value	0.0961366 (rank : 42)	NC score	0.043350 (rank : 105)
Query Neighborhood Hits	232	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

CD2L7_HUMAN
θ value	0.125558 (rank : 43)	NC score	0.017661 (rank : 192)
Query Neighborhood Hits	232	Target Neighborhood Hits	1275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

HELZ_HUMAN
θ value	0.125558 (rank : 44)	NC score	0.038988 (rank : 115)
Query Neighborhood Hits	232	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

INCE_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.043652 (rank : 104)
Query Neighborhood Hits	232	Target Neighborhood Hits	978	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

EVPL_MOUSE
θ value	0.163984 (rank : 46)	NC score	0.034815 (rank : 124)
Query Neighborhood Hits	232	Target Neighborhood Hits	952	Shared Neighborhood Hits	54
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

LIPS_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.049952 (rank : 91)
Query Neighborhood Hits	232	Target Neighborhood Hits	314	Shared Neighborhood Hits	32
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

RPTN_MOUSE
θ value	0.163984 (rank : 48)	NC score	0.049637 (rank : 92)
Query Neighborhood Hits	232	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

AP3B1_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.037028 (rank : 120)
Query Neighborhood Hits	232	Target Neighborhood Hits	283	Shared Neighborhood Hits	30
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DNL1_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.049076 (rank : 95)
Query Neighborhood Hits	232	Target Neighborhood Hits	216	Shared Neighborhood Hits	26
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

IWS1_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.090303 (rank : 33)
Query Neighborhood Hits	232	Target Neighborhood Hits	1241	Shared Neighborhood Hits	108
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	0.21417 (rank : 52)	NC score	0.072707 (rank : 51)
Query Neighborhood Hits	232	Target Neighborhood Hits	1258	Shared Neighborhood Hits	104
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PPIG_HUMAN
θ value	0.21417 (rank : 53)	NC score	0.055438 (rank : 78)
Query Neighborhood Hits	232	Target Neighborhood Hits	670	Shared Neighborhood Hits	73
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

REXO1_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.048902 (rank : 97)
Query Neighborhood Hits	232	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

SRRM1_HUMAN
θ value	0.21417 (rank : 55)	NC score	0.111220 (rank : 26)
Query Neighborhood Hits	232	Target Neighborhood Hits	690	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZO1_MOUSE
θ value	0.21417 (rank : 56)	NC score	0.045357 (rank : 102)
Query Neighborhood Hits	232	Target Neighborhood Hits	453	Shared Neighborhood Hits	42
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AKA12_HUMAN
θ value	0.279714 (rank : 57)	NC score	0.080270 (rank : 41)
Query Neighborhood Hits	232	Target Neighborhood Hits	825	Shared Neighborhood Hits	71
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ARI4A_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.048915 (rank : 96)
Query Neighborhood Hits	232	Target Neighborhood Hits	434	Shared Neighborhood Hits	38
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CYLC2_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.092965 (rank : 32)
Query Neighborhood Hits	232	Target Neighborhood Hits	223	Shared Neighborhood Hits	37
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

LR37A_HUMAN
θ value	0.279714 (rank : 60)	NC score	0.068501 (rank : 56)
Query Neighborhood Hits	232	Target Neighborhood Hits	720	Shared Neighborhood Hits	54
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LY10_HUMAN
θ value	0.279714 (rank : 61)	NC score	0.028066 (rank : 149)
Query Neighborhood Hits	232	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

CABIN_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.074125 (rank : 50)
Query Neighborhood Hits	232	Target Neighborhood Hits	490	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

GOGA6_HUMAN
θ value	0.365318 (rank : 63)	NC score	0.036965 (rank : 121)
Query Neighborhood Hits	232	Target Neighborhood Hits	1007	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

RRBP1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.040940 (rank : 110)
Query Neighborhood Hits	232	Target Neighborhood Hits	1306	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

ZBT38_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.002081 (rank : 247)
Query Neighborhood Hits	232	Target Neighborhood Hits	885	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

IKBL_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.048006 (rank : 98)
Query Neighborhood Hits	232	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

PHF3_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.046184 (rank : 100)
Query Neighborhood Hits	232	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RAI1_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.039680 (rank : 112)
Query Neighborhood Hits	232	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SFR11_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.072383 (rank : 52)
Query Neighborhood Hits	232	Target Neighborhood Hits	246	Shared Neighborhood Hits	36
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

TITIN_HUMAN
θ value	0.47712 (rank : 70)	NC score	0.020603 (rank : 181)
Query Neighborhood Hits	232	Target Neighborhood Hits	2923	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

APXL_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.049329 (rank : 94)
Query Neighborhood Hits	232	Target Neighborhood Hits	553	Shared Neighborhood Hits	35
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

GPTC8_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.068181 (rank : 57)
Query Neighborhood Hits	232	Target Neighborhood Hits	366	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IKBL_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.063970 (rank : 66)
Query Neighborhood Hits	232	Target Neighborhood Hits	196	Shared Neighborhood Hits	21
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

M6PBP_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.026293 (rank : 160)
Query Neighborhood Hits	232	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBG5, Q3TK05, Q8BKV9, Q9CZK1	Gene names	M6prbp1, Tip47
Domain Architecture	No domain graphic available
Description	Mannose-6-phosphate receptor-binding protein 1 (Cargo selection protein TIP47).

MOK_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.015522 (rank : 199)
Query Neighborhood Hits	232	Target Neighborhood Hits	807	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ07, Q92790, Q93067	Gene names	RAGE, MOK, RAGE1
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1).

REXO4_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.057901 (rank : 72)
Query Neighborhood Hits	232	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

RFIP1_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.064245 (rank : 64)
Query Neighborhood Hits	232	Target Neighborhood Hits	236	Shared Neighborhood Hits	32
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TRHY_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.032830 (rank : 129)
Query Neighborhood Hits	232	Target Neighborhood Hits	1385	Shared Neighborhood Hits	65
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ZEP2_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.011730 (rank : 220)
Query Neighborhood Hits	232	Target Neighborhood Hits	964	Shared Neighborhood Hits	43
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ABLM1_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.105324 (rank : 29)
Query Neighborhood Hits	232	Target Neighborhood Hits	387	Shared Neighborhood Hits	28
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

MAP1A_HUMAN
θ value	0.813845 (rank : 81)	NC score	0.070918 (rank : 53)
Query Neighborhood Hits	232	Target Neighborhood Hits	1626	Shared Neighborhood Hits	105
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYPT2_HUMAN
θ value	0.813845 (rank : 82)	NC score	0.029566 (rank : 139)
Query Neighborhood Hits	232	Target Neighborhood Hits	707	Shared Neighborhood Hits	40
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PEPL_HUMAN
θ value	0.813845 (rank : 83)	NC score	0.031597 (rank : 133)
Query Neighborhood Hits	232	Target Neighborhood Hits	1141	Shared Neighborhood Hits	54
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	0.813845 (rank : 84)	NC score	0.031567 (rank : 134)
Query Neighborhood Hits	232	Target Neighborhood Hits	1105	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SMC3_HUMAN
θ value	0.813845 (rank : 85)	NC score	0.032649 (rank : 131)
Query Neighborhood Hits	232	Target Neighborhood Hits	1186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.813845 (rank : 86)	NC score	0.032661 (rank : 130)
Query Neighborhood Hits	232	Target Neighborhood Hits	1187	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

BRD8_MOUSE
θ value	1.06291 (rank : 87)	NC score	0.029189 (rank : 143)
Query Neighborhood Hits	232	Target Neighborhood Hits	422	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BSN_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.083204 (rank : 39)
Query Neighborhood Hits	232	Target Neighborhood Hits	1537	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CD2L1_MOUSE
θ value	1.06291 (rank : 89)	NC score	0.016548 (rank : 195)
Query Neighborhood Hits	232	Target Neighborhood Hits	1463	Shared Neighborhood Hits	61
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

LAD1_MOUSE
θ value	1.06291 (rank : 90)	NC score	0.110824 (rank : 27)
Query Neighborhood Hits	232	Target Neighborhood Hits	391	Shared Neighborhood Hits	59
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LSM3_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.077535 (rank : 45)
Query Neighborhood Hits	232	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P62310, Q9Y4Z1	Gene names	LSM3
Domain Architecture
Description	U6 snRNA-associated Sm-like protein LSm3.

LSM3_MOUSE
θ value	1.06291 (rank : 92)	NC score	0.077535 (rank : 46)
Query Neighborhood Hits	232	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P62311, Q9Y4Z1	Gene names	Lsm3
Domain Architecture
Description	U6 snRNA-associated Sm-like protein LSm3.

TTBK2_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.019318 (rank : 186)
Query Neighborhood Hits	232	Target Neighborhood Hits	811	Shared Neighborhood Hits	33
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

ZC3H6_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.025722 (rank : 165)
Query Neighborhood Hits	232	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

DDX46_MOUSE
θ value	1.38821 (rank : 95)	NC score	0.014582 (rank : 210)
Query Neighborhood Hits	232	Target Neighborhood Hits	358	Shared Neighborhood Hits	31
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DESP_HUMAN
θ value	1.38821 (rank : 96)	NC score	0.028109 (rank : 147)
Query Neighborhood Hits	232	Target Neighborhood Hits	1470	Shared Neighborhood Hits	72
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

GOGA2_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.018599 (rank : 187)
Query Neighborhood Hits	232	Target Neighborhood Hits	856	Shared Neighborhood Hits	34
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

MINT_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.070830 (rank : 54)
Query Neighborhood Hits	232	Target Neighborhood Hits	1291	Shared Neighborhood Hits	95
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.047034 (rank : 99)
Query Neighborhood Hits	232	Target Neighborhood Hits	1242	Shared Neighborhood Hits	90
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PCLO_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.045619 (rank : 101)
Query Neighborhood Hits	232	Target Neighborhood Hits	2275	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PODXL_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.038653 (rank : 116)
Query Neighborhood Hits	232	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PSD3_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.016260 (rank : 197)
Query Neighborhood Hits	232	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

TP53B_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.057787 (rank : 74)
Query Neighborhood Hits	232	Target Neighborhood Hits	644	Shared Neighborhood Hits	59
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRDN_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.076396 (rank : 47)
Query Neighborhood Hits	232	Target Neighborhood Hits	542	Shared Neighborhood Hits	40
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ABLM1_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.101933 (rank : 30)
Query Neighborhood Hits	232	Target Neighborhood Hits	356	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

AFF4_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.053819 (rank : 81)
Query Neighborhood Hits	232	Target Neighborhood Hits	611	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AIM1_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.065028 (rank : 63)
Query Neighborhood Hits	232	Target Neighborhood Hits	247	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ATF2_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.027489 (rank : 152)
Query Neighborhood Hits	232	Target Neighborhood Hits	402	Shared Neighborhood Hits	29
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.027412 (rank : 154)
Query Neighborhood Hits	232	Target Neighborhood Hits	397	Shared Neighborhood Hits	28
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

BPAEA_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.023451 (rank : 174)
Query Neighborhood Hits	232	Target Neighborhood Hits	1369	Shared Neighborhood Hits	57
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCAR1_HUMAN
θ value	1.81305 (rank : 111)	NC score	0.025833 (rank : 164)
Query Neighborhood Hits	232	Target Neighborhood Hits	444	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

MARK4_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.006503 (rank : 230)
Query Neighborhood Hits	232	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MCM2_HUMAN
θ value	1.81305 (rank : 113)	NC score	0.015021 (rank : 204)
Query Neighborhood Hits	232	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MK07_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.011374 (rank : 221)
Query Neighborhood Hits	232	Target Neighborhood Hits	1087	Shared Neighborhood Hits	41
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

NKTR_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.041173 (rank : 109)
Query Neighborhood Hits	232	Target Neighborhood Hits	417	Shared Neighborhood Hits	56
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NUMA1_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.031252 (rank : 135)
Query Neighborhood Hits	232	Target Neighborhood Hits	1523	Shared Neighborhood Hits	72
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RBM25_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.039367 (rank : 113)
Query Neighborhood Hits	232	Target Neighborhood Hits	682	Shared Neighborhood Hits	44
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SNIP1_MOUSE
θ value	1.81305 (rank : 118)	NC score	0.043321 (rank : 106)
Query Neighborhood Hits	232	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

TLE1_MOUSE
θ value	1.81305 (rank : 119)	NC score	0.007739 (rank : 226)
Query Neighborhood Hits	232	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ANR11_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.034332 (rank : 125)
Query Neighborhood Hits	232	Target Neighborhood Hits	1289	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

GCC1_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.021939 (rank : 176)
Query Neighborhood Hits	232	Target Neighborhood Hits	887	Shared Neighborhood Hits	42
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

LYSM2_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.025140 (rank : 167)
Query Neighborhood Hits	232	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IV50, Q5CZ88, Q8WTV3	Gene names	LYSMD2
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 2.

REN3B_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.037699 (rank : 119)
Query Neighborhood Hits	232	Target Neighborhood Hits	412	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RRBP1_MOUSE
θ value	2.36792 (rank : 124)	NC score	0.041497 (rank : 108)
Query Neighborhood Hits	232	Target Neighborhood Hits	1650	Shared Neighborhood Hits	93
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ZNF18_HUMAN
θ value	2.36792 (rank : 125)	NC score	-0.001311 (rank : 249)
Query Neighborhood Hits	232	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	P17022, Q5QHQ3, Q8IYC4, Q8NAH6	Gene names	ZNF18, HDSG1, KOX11
Domain Architecture	No domain graphic available
Description	Zinc finger protein 18 (Zinc finger protein KOX11) (Heart development- specific gene 1 protein).

ZO1_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.032409 (rank : 132)
Query Neighborhood Hits	232	Target Neighborhood Hits	474	Shared Neighborhood Hits	41
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CD2L1_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.014763 (rank : 208)
Query Neighborhood Hits	232	Target Neighborhood Hits	1467	Shared Neighborhood Hits	58
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

DNJC1_HUMAN
θ value	3.0926 (rank : 128)	NC score	0.011737 (rank : 219)
Query Neighborhood Hits	232	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KC8	Gene names	DNAJC1
Domain Architecture
Description	DnaJ homolog subfamily C member 1.

ERCC5_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.019611 (rank : 185)
Query Neighborhood Hits	232	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

HIRP3_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.052422 (rank : 87)
Query Neighborhood Hits	232	Target Neighborhood Hits	323	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

MAP1B_MOUSE
θ value	3.0926 (rank : 131)	NC score	0.053538 (rank : 82)
Query Neighborhood Hits	232	Target Neighborhood Hits	977	Shared Neighborhood Hits	74
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MUC1_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.039024 (rank : 114)
Query Neighborhood Hits	232	Target Neighborhood Hits	388	Shared Neighborhood Hits	30
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NCOR1_MOUSE
θ value	3.0926 (rank : 133)	NC score	0.035556 (rank : 122)
Query Neighborhood Hits	232	Target Neighborhood Hits	521	Shared Neighborhood Hits	55
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NRG2_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.025270 (rank : 166)
Query Neighborhood Hits	232	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

RADI_HUMAN
θ value	3.0926 (rank : 135)	NC score	0.014941 (rank : 206)
Query Neighborhood Hits	232	Target Neighborhood Hits	741	Shared Neighborhood Hits	40
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

SENP7_HUMAN
θ value	3.0926 (rank : 136)	NC score	0.023856 (rank : 171)
Query Neighborhood Hits	232	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

TNIK_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.009302 (rank : 225)
Query Neighborhood Hits	232	Target Neighborhood Hits	1570	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

AP3B1_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.028083 (rank : 148)
Query Neighborhood Hits	232	Target Neighborhood Hits	302	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

EP400_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.026314 (rank : 159)
Query Neighborhood Hits	232	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EVL_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.026099 (rank : 163)
Query Neighborhood Hits	232	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

HRX_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.033363 (rank : 127)
Query Neighborhood Hits	232	Target Neighborhood Hits	825	Shared Neighborhood Hits	60
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LAD1_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.065260 (rank : 60)
Query Neighborhood Hits	232	Target Neighborhood Hits	441	Shared Neighborhood Hits	57
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MARK4_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.006250 (rank : 232)
Query Neighborhood Hits	232	Target Neighborhood Hits	886	Shared Neighborhood Hits	24
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

NCOA1_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.009529 (rank : 224)
Query Neighborhood Hits	232	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

PLEC1_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.027609 (rank : 151)
Query Neighborhood Hits	232	Target Neighborhood Hits	1326	Shared Neighborhood Hits	53
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PZRN3_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.014065 (rank : 213)
Query Neighborhood Hits	232	Target Neighborhood Hits	461	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	4.03905 (rank : 147)	NC score	0.012950 (rank : 216)
Query Neighborhood Hits	232	Target Neighborhood Hits	447	Shared Neighborhood Hits	19
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SFR12_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.057805 (rank : 73)
Query Neighborhood Hits	232	Target Neighborhood Hits	553	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SRRM1_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.097846 (rank : 31)
Query Neighborhood Hits	232	Target Neighborhood Hits	966	Shared Neighborhood Hits	84
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TCOF_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.075402 (rank : 48)
Query Neighborhood Hits	232	Target Neighborhood Hits	471	Shared Neighborhood Hits	53
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TEX2_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.021451 (rank : 177)
Query Neighborhood Hits	232	Target Neighborhood Hits	121	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TFG_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.033788 (rank : 126)
Query Neighborhood Hits	232	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

UBP21_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.005624 (rank : 235)
Query Neighborhood Hits	232	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

ZN638_MOUSE
θ value	4.03905 (rank : 154)	NC score	0.029415 (rank : 141)
Query Neighborhood Hits	232	Target Neighborhood Hits	318	Shared Neighborhood Hits	29
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

BRE1A_HUMAN
θ value	5.27518 (rank : 155)	NC score	0.016096 (rank : 198)
Query Neighborhood Hits	232	Target Neighborhood Hits	1071	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CDA7L_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.029437 (rank : 140)
Query Neighborhood Hits	232	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q922M5	Gene names	Cdca7l
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Transcription factor RAM2).

CDCA7_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.040207 (rank : 111)
Query Neighborhood Hits	232	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWT1, Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8, Q96SP5	Gene names	CDCA7, JPO1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7 (Protein JPO1).

CE110_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.014498 (rank : 211)
Query Neighborhood Hits	232	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CHD6_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.012792 (rank : 217)
Query Neighborhood Hits	232	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

FGD1_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.006676 (rank : 228)
Query Neighborhood Hits	232	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HDGF_MOUSE
θ value	5.27518 (rank : 161)	NC score	0.015227 (rank : 203)
Query Neighborhood Hits	232	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

IF2P_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.030627 (rank : 136)
Query Neighborhood Hits	232	Target Neighborhood Hits	889	Shared Neighborhood Hits	52
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MCM2_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.012715 (rank : 218)
Query Neighborhood Hits	232	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

NKTR_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.053116 (rank : 85)
Query Neighborhood Hits	232	Target Neighborhood Hits	658	Shared Neighborhood Hits	74
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NRG2_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.014931 (rank : 207)
Query Neighborhood Hits	232	Target Neighborhood Hits	392	Shared Neighborhood Hits	8
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

RIMB1_MOUSE
θ value	5.27518 (rank : 166)	NC score	0.026594 (rank : 158)
Query Neighborhood Hits	232	Target Neighborhood Hits	1376	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SDC3_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.024960 (rank : 168)
Query Neighborhood Hits	232	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SOX14_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.006410 (rank : 231)
Query Neighborhood Hits	232	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

WDR74_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.013545 (rank : 215)
Query Neighborhood Hits	232	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

AFF3_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.038145 (rank : 118)
Query Neighborhood Hits	232	Target Neighborhood Hits	190	Shared Neighborhood Hits	27
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

APC_MOUSE
θ value	6.88961 (rank : 171)	NC score	0.024485 (rank : 169)
Query Neighborhood Hits	232	Target Neighborhood Hits	441	Shared Neighborhood Hits	34
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CO002_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.027387 (rank : 155)
Query Neighborhood Hits	232	Target Neighborhood Hits	387	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CRTC1_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.020743 (rank : 179)
Query Neighborhood Hits	232	Target Neighborhood Hits	230	Shared Neighborhood Hits	22
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CYLC1_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.051152 (rank : 89)
Query Neighborhood Hits	232	Target Neighborhood Hits	408	Shared Neighborhood Hits	35
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

FA44A_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.022157 (rank : 175)
Query Neighborhood Hits	232	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

IRAK1_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.004351 (rank : 238)
Query Neighborhood Hits	232	Target Neighborhood Hits	820	Shared Neighborhood Hits	21
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

JHD2C_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.020043 (rank : 183)
Query Neighborhood Hits	232	Target Neighborhood Hits	297	Shared Neighborhood Hits	32
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

K1802_MOUSE
θ value	6.88961 (rank : 178)	NC score	0.026263 (rank : 162)
Query Neighborhood Hits	232	Target Neighborhood Hits	1596	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL3_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.033143 (rank : 128)
Query Neighborhood Hits	232	Target Neighborhood Hits	1399	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYPN_MOUSE
θ value	6.88961 (rank : 180)	NC score	0.016294 (rank : 196)
Query Neighborhood Hits	232	Target Neighborhood Hits	421	Shared Neighborhood Hits	22
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

MYRIP_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.014622 (rank : 209)
Query Neighborhood Hits	232	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NOL7_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.018083 (rank : 189)
Query Neighborhood Hits	232	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMY1, Q5T297, Q9Y3U7	Gene names	NOL7, C6orf90, NOP27
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7 (Nucleolar protein of 27 kDa).

PHAR3_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.026288 (rank : 161)
Query Neighborhood Hits	232	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PHAR3_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.023850 (rank : 172)
Query Neighborhood Hits	232	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PRKDC_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.007613 (rank : 227)
Query Neighborhood Hits	232	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

RADI_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.013549 (rank : 214)
Query Neighborhood Hits	232	Target Neighborhood Hits	773	Shared Neighborhood Hits	38
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

STK23_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.014410 (rank : 212)
Query Neighborhood Hits	232	Target Neighborhood Hits	572	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0G2	Gene names	Stk23, Mssk1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

SYMPK_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.020696 (rank : 180)
Query Neighborhood Hits	232	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.018416 (rank : 188)
Query Neighborhood Hits	232	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

TPM1_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.015472 (rank : 201)
Query Neighborhood Hits	232	Target Neighborhood Hits	716	Shared Neighborhood Hits	37
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.015494 (rank : 200)
Query Neighborhood Hits	232	Target Neighborhood Hits	729	Shared Neighborhood Hits	37
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

ZN202_HUMAN
θ value	6.88961 (rank : 192)	NC score	-0.002110 (rank : 250)
Query Neighborhood Hits	232	Target Neighborhood Hits	756	Shared Neighborhood Hits	16
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

ZN438_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.003447 (rank : 245)
Query Neighborhood Hits	232	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ABL1_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.003155 (rank : 246)
Query Neighborhood Hits	232	Target Neighborhood Hits	1220	Shared Neighborhood Hits	36
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ACINU_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.088703 (rank : 34)
Query Neighborhood Hits	232	Target Neighborhood Hits	712	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF4_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.049389 (rank : 93)
Query Neighborhood Hits	232	Target Neighborhood Hits	581	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ANK1_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.010900 (rank : 223)
Query Neighborhood Hits	232	Target Neighborhood Hits	416	Shared Neighborhood Hits	21
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR47_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.014990 (rank : 205)
Query Neighborhood Hits	232	Target Neighborhood Hits	369	Shared Neighborhood Hits	14
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ARS2_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.023925 (rank : 170)
Query Neighborhood Hits	232	Target Neighborhood Hits	212	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

ATX2L_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.020847 (rank : 178)
Query Neighborhood Hits	232	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

AUTS2_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.027449 (rank : 153)
Query Neighborhood Hits	232	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAZ2A_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.023532 (rank : 173)
Query Neighborhood Hits	232	Target Neighborhood Hits	744	Shared Neighborhood Hits	52
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BLM_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.006554 (rank : 229)
Query Neighborhood Hits	232	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

CCD96_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.029991 (rank : 138)
Query Neighborhood Hits	232	Target Neighborhood Hits	704	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CS029_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.016640 (rank : 194)
Query Neighborhood Hits	232	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CT116_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.016877 (rank : 193)
Query Neighborhood Hits	232	Target Neighborhood Hits	294	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

DC1I2_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.005654 (rank : 234)
Query Neighborhood Hits	232	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DEK_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.029372 (rank : 142)
Query Neighborhood Hits	232	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

GCC1_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.020206 (rank : 182)
Query Neighborhood Hits	232	Target Neighborhood Hits	777	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

LAP2_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.028767 (rank : 144)
Query Neighborhood Hits	232	Target Neighborhood Hits	482	Shared Neighborhood Hits	17
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

OPTN_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.028542 (rank : 146)
Query Neighborhood Hits	232	Target Neighborhood Hits	1120	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PCDH7_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.001095 (rank : 248)
Query Neighborhood Hits	232	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PDE3A_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.004238 (rank : 240)
Query Neighborhood Hits	232	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDGFD_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.005880 (rank : 233)
Query Neighborhood Hits	232	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PHAR1_HUMAN
θ value	8.99809 (rank : 215)	NC score	0.017749 (rank : 191)
Query Neighborhood Hits	232	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

PHAR1_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.017762 (rank : 190)
Query Neighborhood Hits	232	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

PRL_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.004706 (rank : 237)
Query Neighborhood Hits	232	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P01236, Q15199, Q92996	Gene names	PRL
Domain Architecture
Description	Prolactin precursor (PRL).

RARG1_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.003855 (rank : 241)
Query Neighborhood Hits	232	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	8.99809 (rank : 219)	NC score	0.003774 (rank : 243)
Query Neighborhood Hits	232	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.003823 (rank : 242)
Query Neighborhood Hits	232	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	8.99809 (rank : 221)	NC score	0.003739 (rank : 244)
Query Neighborhood Hits	232	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

SDC3_MOUSE
θ value	8.99809 (rank : 222)	NC score	0.026926 (rank : 157)
Query Neighborhood Hits	232	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SFR12_MOUSE
θ value	8.99809 (rank : 223)	NC score	0.053324 (rank : 84)
Query Neighborhood Hits	232	Target Neighborhood Hits	486	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SIGL9_HUMAN
θ value	8.99809 (rank : 224)	NC score	0.004292 (rank : 239)
Query Neighborhood Hits	232	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

SMC2_MOUSE
θ value	8.99809 (rank : 225)	NC score	0.028655 (rank : 145)
Query Neighborhood Hits	232	Target Neighborhood Hits	1131	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SOX14_HUMAN
θ value	8.99809 (rank : 226)	NC score	0.005060 (rank : 236)
Query Neighborhood Hits	232	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SURF6_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.015262 (rank : 202)
Query Neighborhood Hits	232	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	O75683, Q9BRK9, Q9BTZ5, Q9UK24	Gene names	SURF6, SURF-6
Domain Architecture
Description	Surfeit locus protein 6.

TARA_MOUSE
θ value	8.99809 (rank : 228)	NC score	0.042376 (rank : 107)
Query Neighborhood Hits	232	Target Neighborhood Hits	1133	Shared Neighborhood Hits	80
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRA2A_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.019784 (rank : 184)
Query Neighborhood Hits	232	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q13595	Gene names	TRA2A
Domain Architecture
Description	Transformer-2 protein homolog (TRA-2 alpha).

X3CL1_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.011161 (rank : 222)
Query Neighborhood Hits	232	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZBT16_HUMAN
θ value	8.99809 (rank : 231)	NC score	-0.002241 (rank : 251)
Query Neighborhood Hits	232	Target Neighborhood Hits	1010	Shared Neighborhood Hits	20
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZN282_HUMAN
θ value	8.99809 (rank : 232)	NC score	-0.002613 (rank : 252)
Query Neighborhood Hits	232	Target Neighborhood Hits	796	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

AFF1_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.055833 (rank : 77)
Query Neighborhood Hits	232	Target Neighborhood Hits	351	Shared Neighborhood Hits	36
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

BASP_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.053405 (rank : 83)
Query Neighborhood Hits	232	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.052324 (rank : 88)
Query Neighborhood Hits	232	Target Neighborhood Hits	260	Shared Neighborhood Hits	33
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CJ078_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.057247 (rank : 76)
Query Neighborhood Hits	232	Target Neighborhood Hits	559	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.057327 (rank : 75)
Query Neighborhood Hits	232	Target Neighborhood Hits	385	Shared Neighborhood Hits	46
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

KI67_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.064071 (rank : 65)
Query Neighborhood Hits	232	Target Neighborhood Hits	581	Shared Neighborhood Hits	74
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MDC1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.065030 (rank : 62)
Query Neighborhood Hits	232	Target Neighborhood Hits	1446	Shared Neighborhood Hits	103
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.055380 (rank : 79)
Query Neighborhood Hits	232	Target Neighborhood Hits	998	Shared Neighborhood Hits	91
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NIPBL_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.079230 (rank : 42)
Query Neighborhood Hits	232	Target Neighborhood Hits	1311	Shared Neighborhood Hits	114
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOLC1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.078973 (rank : 44)
Query Neighborhood Hits	232	Target Neighborhood Hits	452	Shared Neighborhood Hits	53
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NPBL_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.062844 (rank : 67)
Query Neighborhood Hits	232	Target Neighborhood Hits	1041	Shared Neighborhood Hits	101
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PCLO_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.052471 (rank : 86)
Query Neighborhood Hits	232	Target Neighborhood Hits	2046	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RBBP6_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.085341 (rank : 37)
Query Neighborhood Hits	232	Target Neighborhood Hits	1014	Shared Neighborhood Hits	92
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SFRIP_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.058139 (rank : 71)
Query Neighborhood Hits	232	Target Neighborhood Hits	530	Shared Neighborhood Hits	71
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TARA_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.059773 (rank : 69)
Query Neighborhood Hits	232	Target Neighborhood Hits	1626	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCOF_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.065035 (rank : 61)
Query Neighborhood Hits	232	Target Neighborhood Hits	543	Shared Neighborhood Hits	54
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.058334 (rank : 70)
Query Neighborhood Hits	232	Target Neighborhood Hits	1037	Shared Neighborhood Hits	93
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TM131_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.050833 (rank : 90)
Query Neighborhood Hits	232	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

TXND2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.074367 (rank : 49)
Query Neighborhood Hits	232	Target Neighborhood Hits	793	Shared Neighborhood Hits	83
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.054841 (rank : 80)
Query Neighborhood Hits	232	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

SVIL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	232	Target Neighborhood Hits	232	Shared Neighborhood Hits	232
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SVIL_MOUSE
NC score	0.929208 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	232	Target Neighborhood Hits	439	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

AVIL_MOUSE
NC score	0.768167 (rank : 3)	θ value	1.56636e-44 (rank : 4)
Query Neighborhood Hits	232	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	O88398, O70466	Gene names	Avil, Advil
Domain Architecture
Description	Advillin (p92) (Actin-binding protein DOC6).

AVIL_HUMAN
NC score	0.767929 (rank : 4)	θ value	7.03111e-45 (rank : 3)
Query Neighborhood Hits	232	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	O75366	Gene names	AVIL
Domain Architecture
Description	Advillin (p92).

VILI_HUMAN
NC score	0.767017 (rank : 5)	θ value	7.77379e-44 (rank : 6)
Query Neighborhood Hits	232	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P09327	Gene names	VIL1, VIL
Domain Architecture
Description	Villin-1.

VILI_MOUSE
NC score	0.766913 (rank : 6)	θ value	3.48949e-44 (rank : 5)
Query Neighborhood Hits	232	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q62468, Q91WH4	Gene names	Vil1, Vil
Domain Architecture
Description	Villin-1.

VILL_HUMAN
NC score	0.763939 (rank : 7)	θ value	7.52953e-39 (rank : 7)
Query Neighborhood Hits	232	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	O15195, Q9BT80, Q9BWH7	Gene names	VILL
Domain Architecture
Description	Villin-like protein.

VILL_MOUSE
NC score	0.752427 (rank : 8)	θ value	8.91499e-32 (rank : 10)
Query Neighborhood Hits	232	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q91YD6, P97809, Q8BIS5, Q8R211, Q8VDI8	Gene names	Vill, Villp
Domain Architecture	No domain graphic available
Description	Villin-like protein (EF-6).

GELS_HUMAN
NC score	0.736303 (rank : 9)	θ value	1.0531e-32 (rank : 9)
Query Neighborhood Hits	232	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	P06396, Q8WVV7	Gene names	GSN
Domain Architecture
Description	Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL).

GELS_MOUSE
NC score	0.735821 (rank : 10)	θ value	8.06329e-33 (rank : 8)
Query Neighborhood Hits	232	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	P13020, Q3UPB1, Q8R590	Gene names	Gsn, Gsb
Domain Architecture
Description	Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin).

ADSV_HUMAN
NC score	0.735099 (rank : 11)	θ value	5.77852e-31 (rank : 11)
Query Neighborhood Hits	232	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6U3, Q8NBZ6, Q8WU97, Q96JC7, Q96PY2	Gene names	SCIN, KIAA1905
Domain Architecture
Description	Adseverin (Scinderin).

ADSV_MOUSE
NC score	0.733114 (rank : 12)	θ value	6.38894e-30 (rank : 12)
Query Neighborhood Hits	232	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	Q60604, O08988, O08990	Gene names	Scin
Domain Architecture
Description	Adseverin (Scinderin) (Gelsolin-like protein).

CAPG_HUMAN
NC score	0.668873 (rank : 13)	θ value	2.13673e-09 (rank : 15)
Query Neighborhood Hits	232	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	P40121	Gene names	CAPG, MCP
Domain Architecture
Description	Macrophage capping protein (Actin-regulatory protein CAP-G).

CAPG_MOUSE
NC score	0.660029 (rank : 14)	θ value	8.11959e-09 (rank : 16)
Query Neighborhood Hits	232	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P24452	Gene names	Capg, Mbh1
Domain Architecture
Description	Macrophage capping protein (Myc basic motif homolog 1) (Actin-capping protein GCAP39).

FLII_MOUSE
NC score	0.412366 (rank : 15)	θ value	7.0802e-21 (rank : 14)
Query Neighborhood Hits	232	Target Neighborhood Hits	304	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJ28, Q8K095, Q8VI44	Gene names	Flii, Fli1, Fliih
Domain Architecture	No domain graphic available
Description	Protein flightless-1 homolog.

FLII_HUMAN
NC score	0.409615 (rank : 16)	θ value	1.09232e-21 (rank : 13)
Query Neighborhood Hits	232	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

DEMA_MOUSE
NC score	0.278645 (rank : 17)	θ value	0.000461057 (rank : 19)
Query Neighborhood Hits	232	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DEMA_HUMAN
NC score	0.276823 (rank : 18)	θ value	0.000461057 (rank : 18)
Query Neighborhood Hits	232	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q08495, Q13215, Q9BRE3	Gene names	EPB49, DMT
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

ABLM3_HUMAN
NC score	0.140993 (rank : 19)	θ value	0.00509761 (rank : 24)
Query Neighborhood Hits	232	Target Neighborhood Hits	293	Shared Neighborhood Hits	24
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_MOUSE
NC score	0.139773 (rank : 20)	θ value	0.00665767 (rank : 25)
Query Neighborhood Hits	232	Target Neighborhood Hits	294	Shared Neighborhood Hits	22
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

SRRM2_MOUSE
NC score	0.139478 (rank : 21)	θ value	0.000121331 (rank : 17)
Query Neighborhood Hits	232	Target Neighborhood Hits	1470	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ABLM2_HUMAN
NC score	0.136612 (rank : 22)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	232	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

ABLM2_MOUSE
NC score	0.136241 (rank : 23)	θ value	0.00390308 (rank : 23)
Query Neighborhood Hits	232	Target Neighborhood Hits	306	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

SRRM2_HUMAN
NC score	0.122708 (rank : 24)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	232	Target Neighborhood Hits	1296	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SFR17_HUMAN
NC score	0.115035 (rank : 25)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	232	Target Neighborhood Hits	325	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SRRM1_HUMAN
NC score	0.111220 (rank : 26)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	232	Target Neighborhood Hits	690	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

LAD1_MOUSE
NC score	0.110824 (rank : 27)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	232	Target Neighborhood Hits	391	Shared Neighborhood Hits	59
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

ACINU_HUMAN
NC score	0.109332 (rank : 28)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	232	Target Neighborhood Hits	828	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ABLM1_HUMAN
NC score	0.105324 (rank : 29)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	232	Target Neighborhood Hits	387	Shared Neighborhood Hits	28
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ABLM1_MOUSE
NC score	0.101933 (rank : 30)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	232	Target Neighborhood Hits	356	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

SRRM1_MOUSE
NC score	0.097846 (rank : 31)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	232	Target Neighborhood Hits	966	Shared Neighborhood Hits	84
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CYLC2_HUMAN
NC score	0.092965 (rank : 32)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	232	Target Neighborhood Hits	223	Shared Neighborhood Hits	37
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

IWS1_HUMAN
NC score	0.090303 (rank : 33)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	232	Target Neighborhood Hits	1241	Shared Neighborhood Hits	108
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ACINU_MOUSE
NC score	0.088703 (rank : 34)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	232	Target Neighborhood Hits	712	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MINT_MOUSE
NC score	0.087202 (rank : 35)	θ value	0.00175202 (rank : 20)
Query Neighborhood Hits	232	Target Neighborhood Hits	1514	Shared Neighborhood Hits	102
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RBBP6_HUMAN
NC score	0.085935 (rank : 36)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	232	Target Neighborhood Hits	1135	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
NC score	0.085341 (rank : 37)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	232	Target Neighborhood Hits	1014	Shared Neighborhood Hits	92
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ZC313_HUMAN
NC score	0.083437 (rank : 38)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	232	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

BSN_HUMAN
NC score	0.083204 (rank : 39)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	232	Target Neighborhood Hits	1537	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CDCA7_MOUSE
NC score	0.081847 (rank : 40)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	232	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D0M2, Q3TIS1, Q3U511, Q6NZE5, Q8C1A0	Gene names	Cdca7
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7.

AKA12_HUMAN
NC score	0.080270 (rank : 41)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	232	Target Neighborhood Hits	825	Shared Neighborhood Hits	71
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

NIPBL_HUMAN
NC score	0.079230 (rank : 42)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	232	Target Neighborhood Hits	1311	Shared Neighborhood Hits	114
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

BSN_MOUSE
NC score	0.078983 (rank : 43)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	232	Target Neighborhood Hits	2057	Shared Neighborhood Hits	96
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NOLC1_HUMAN
NC score	0.078973 (rank : 44)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	232	Target Neighborhood Hits	452	Shared Neighborhood Hits	53
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

LSM3_HUMAN
NC score	0.077535 (rank : 45)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	232	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P62310, Q9Y4Z1	Gene names	LSM3
Domain Architecture
Description	U6 snRNA-associated Sm-like protein LSm3.

LSM3_MOUSE
NC score	0.077535 (rank : 46)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	232	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P62311, Q9Y4Z1	Gene names	Lsm3
Domain Architecture
Description	U6 snRNA-associated Sm-like protein LSm3.

TRDN_HUMAN
NC score	0.076396 (rank : 47)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	232	Target Neighborhood Hits	542	Shared Neighborhood Hits	40
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TCOF_MOUSE
NC score	0.075402 (rank : 48)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	232	Target Neighborhood Hits	471	Shared Neighborhood Hits	53
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TXND2_HUMAN
NC score	0.074367 (rank : 49)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	232	Target Neighborhood Hits	793	Shared Neighborhood Hits	83
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CABIN_HUMAN
NC score	0.074125 (rank : 50)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	232	Target Neighborhood Hits	490	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

IWS1_MOUSE
NC score	0.072707 (rank : 51)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	232	Target Neighborhood Hits	1258	Shared Neighborhood Hits	104
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SFR11_HUMAN
NC score	0.072383 (rank : 52)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	232	Target Neighborhood Hits	246	Shared Neighborhood Hits	36
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

MAP1A_HUMAN
NC score	0.070918 (rank : 53)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	232	Target Neighborhood Hits	1626	Shared Neighborhood Hits	105
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MINT_HUMAN
NC score	0.070830 (rank : 54)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	232	Target Neighborhood Hits	1291	Shared Neighborhood Hits	95
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NACAM_MOUSE
NC score	0.068859 (rank : 55)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	232	Target Neighborhood Hits	1866	Shared Neighborhood Hits	94
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LR37A_HUMAN
NC score	0.068501 (rank : 56)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	232	Target Neighborhood Hits	720	Shared Neighborhood Hits	54
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

GPTC8_HUMAN
NC score	0.068181 (rank : 57)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	232	Target Neighborhood Hits	366	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SETD2_HUMAN
NC score	0.068164 (rank : 58)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	232	Target Neighborhood Hits	412	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

NFH_MOUSE
NC score	0.067576 (rank : 59)	θ value	0.00228821 (rank : 21)
Query Neighborhood Hits	232	Target Neighborhood Hits	2247	Shared Neighborhood Hits	129
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LAD1_HUMAN
NC score	0.065260 (rank : 60)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	232	Target Neighborhood Hits	441	Shared Neighborhood Hits	57
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

TCOF_HUMAN
NC score	0.065035 (rank : 61)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	232	Target Neighborhood Hits	543	Shared Neighborhood Hits	54
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MDC1_HUMAN
NC score	0.065030 (rank : 62)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	232	Target Neighborhood Hits	1446	Shared Neighborhood Hits	103
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

AIM1_HUMAN
NC score	0.065028 (rank : 63)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	232	Target Neighborhood Hits	247	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

RFIP1_HUMAN
NC score	0.064245 (rank : 64)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	232	Target Neighborhood Hits	236	Shared Neighborhood Hits	32
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

KI67_HUMAN
NC score	0.064071 (rank : 65)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	232	Target Neighborhood Hits	581	Shared Neighborhood Hits	74
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

IKBL_MOUSE
NC score	0.063970 (rank : 66)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	232	Target Neighborhood Hits	196	Shared Neighborhood Hits	21
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

NPBL_MOUSE
NC score	0.062844 (rank : 67)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	232	Target Neighborhood Hits	1041	Shared Neighborhood Hits	101
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

OXR1_MOUSE
NC score	0.062162 (rank : 68)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	232	Target Neighborhood Hits	516	Shared Neighborhood Hits	65
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

TARA_HUMAN
NC score	0.059773 (rank : 69)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	232	Target Neighborhood Hits	1626	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGON2_HUMAN
NC score	0.058334 (rank : 70)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	232	Target Neighborhood Hits	1037	Shared Neighborhood Hits	93
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SFRIP_HUMAN
NC score	0.058139 (rank : 71)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	232	Target Neighborhood Hits	530	Shared Neighborhood Hits	71
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

REXO4_HUMAN
NC score	0.057901 (rank : 72)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	232	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

SFR12_HUMAN
NC score	0.057805 (rank : 73)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	232	Target Neighborhood Hits	553	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

TP53B_MOUSE
NC score	0.057787 (rank : 74)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	232	Target Neighborhood Hits	644	Shared Neighborhood Hits	59
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CN155_HUMAN
NC score	0.057327 (rank : 75)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	232	Target Neighborhood Hits	385	Shared Neighborhood Hits	46
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CJ078_MOUSE
NC score	0.057247 (rank : 76)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	232	Target Neighborhood Hits	559	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

AFF1_MOUSE
NC score	0.055833 (rank : 77)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	232	Target Neighborhood Hits	351	Shared Neighborhood Hits	36
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

PPIG_HUMAN
NC score	0.055438 (rank : 78)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	232	Target Neighborhood Hits	670	Shared Neighborhood Hits	73
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

MDC1_MOUSE
NC score	0.055380 (rank : 79)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	232	Target Neighborhood Hits	998	Shared Neighborhood Hits	91
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

TXND2_MOUSE
NC score	0.054841 (rank : 80)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	232	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

AFF4_HUMAN
NC score	0.053819 (rank : 81)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	232	Target Neighborhood Hits	611	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

MAP1B_MOUSE
NC score	0.053538 (rank : 82)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	232	Target Neighborhood Hits	977	Shared Neighborhood Hits	74
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BASP_HUMAN
NC score	0.053405 (rank : 83)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	232	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SFR12_MOUSE
NC score	0.053324 (rank : 84)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	232	Target Neighborhood Hits	486	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

NKTR_HUMAN
NC score	0.053116 (rank : 85)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	232	Target Neighborhood Hits	658	Shared Neighborhood Hits	74
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PCLO_HUMAN
NC score	0.052471 (rank : 86)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	232	Target Neighborhood Hits	2046	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HIRP3_HUMAN
NC score	0.052422 (rank : 87)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	232	Target Neighborhood Hits	323	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

BASP_MOUSE
NC score	0.052324 (rank : 88)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	232	Target Neighborhood Hits	260	Shared Neighborhood Hits	33
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CYLC1_HUMAN
NC score	0.051152 (rank : 89)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	232	Target Neighborhood Hits	408	Shared Neighborhood Hits	35
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TM131_MOUSE
NC score	0.050833 (rank : 90)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	232	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

LIPS_HUMAN
NC score	0.049952 (rank : 91)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	232	Target Neighborhood Hits	314	Shared Neighborhood Hits	32
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

RPTN_MOUSE
NC score	0.049637 (rank : 92)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	232	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

AFF4_MOUSE
NC score	0.049389 (rank : 93)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	232	Target Neighborhood Hits	581	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

APXL_HUMAN
NC score	0.049329 (rank : 94)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	232	Target Neighborhood Hits	553	Shared Neighborhood Hits	35
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DNL1_HUMAN
NC score	0.049076 (rank : 95)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	232	Target Neighborhood Hits	216	Shared Neighborhood Hits	26
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

ARI4A_HUMAN
NC score	0.048915 (rank : 96)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	232	Target Neighborhood Hits	434	Shared Neighborhood Hits	38
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

REXO1_MOUSE
NC score	0.048902 (rank : 97)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	232	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

IKBL_HUMAN
NC score	0.048006 (rank : 98)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	232	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

NFH_HUMAN
NC score	0.047034 (rank : 99)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	232	Target Neighborhood Hits	1242	Shared Neighborhood Hits	90
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF3_HUMAN
NC score	0.046184 (rank : 100)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	232	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PCLO_MOUSE
NC score	0.045619 (rank : 101)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	232	Target Neighborhood Hits	2275	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZO1_MOUSE
NC score	0.045357 (rank : 102)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	232	Target Neighborhood Hits	453	Shared Neighborhood Hits	42
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ANK2_HUMAN
NC score	0.044890 (rank : 103)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	232	Target Neighborhood Hits	1615	Shared Neighborhood Hits	107
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

INCE_HUMAN
NC score	0.043652 (rank : 104)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	232	Target Neighborhood Hits	978	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LIMD1_MOUSE
NC score	0.043350 (rank : 105)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	232	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

SNIP1_MOUSE
NC score	0.043321 (rank : 106)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	232	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

TARA_MOUSE
NC score	0.042376 (rank : 107)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	232	Target Neighborhood Hits	1133	Shared Neighborhood Hits	80
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RRBP1_MOUSE
NC score	0.041497 (rank : 108)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	232	Target Neighborhood Hits	1650	Shared Neighborhood Hits	93
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NKTR_MOUSE
NC score	0.041173 (rank : 109)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	232	Target Neighborhood Hits	417	Shared Neighborhood Hits	56
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RRBP1_HUMAN
NC score	0.040940 (rank : 110)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	232	Target Neighborhood Hits	1306	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CDCA7_HUMAN
NC score	0.040207 (rank : 111)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	232	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWT1, Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8, Q96SP5	Gene names	CDCA7, JPO1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7 (Protein JPO1).

RAI1_HUMAN
NC score	0.039680 (rank : 112)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	232	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RBM25_HUMAN
NC score	0.039367 (rank : 113)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	232	Target Neighborhood Hits	682	Shared Neighborhood Hits	44
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

MUC1_MOUSE
NC score	0.039024 (rank : 114)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	232	Target Neighborhood Hits	388	Shared Neighborhood Hits	30
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

HELZ_HUMAN
NC score	0.038988 (rank : 115)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	232	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

PODXL_HUMAN
NC score	0.038653 (rank : 116)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	232	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PRP4B_MOUSE
NC score	0.038167 (rank : 117)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	232	Target Neighborhood Hits	1040	Shared Neighborhood Hits	54
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

AFF3_HUMAN
NC score	0.038145 (rank : 118)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	232	Target Neighborhood Hits	190	Shared Neighborhood Hits	27
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

REN3B_HUMAN
NC score	0.037699 (rank : 119)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	232	Target Neighborhood Hits	412	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

AP3B1_HUMAN
NC score	0.037028 (rank : 120)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	232	Target Neighborhood Hits	283	Shared Neighborhood Hits	30
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

GOGA6_HUMAN
NC score	0.036965 (rank : 121)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	232	Target Neighborhood Hits	1007	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NCOR1_MOUSE
NC score	0.035556 (rank : 122)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	232	Target Neighborhood Hits	521	Shared Neighborhood Hits	55
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PRP4B_HUMAN
NC score	0.035299 (rank : 123)	θ value	0.0148317 (rank : 29)
Query Neighborhood Hits	232	Target Neighborhood Hits	1030	Shared Neighborhood Hits	47
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

EVPL_MOUSE
NC score	0.034815 (rank : 124)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	232	Target Neighborhood Hits	952	Shared Neighborhood Hits	54
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

ANR11_HUMAN
NC score	0.034332 (rank : 125)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	232	Target Neighborhood Hits	1289	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

TFG_HUMAN
NC score	0.033788 (rank : 126)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	232	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

HRX_HUMAN
NC score	0.033363 (rank : 127)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	232	Target Neighborhood Hits	825	Shared Neighborhood Hits	60
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL3_MOUSE
NC score	0.033143 (rank : 128)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	232	Target Neighborhood Hits	1399	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TRHY_HUMAN
NC score	0.032830 (rank : 129)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	232	Target Neighborhood Hits	1385	Shared Neighborhood Hits	65
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

SMC3_MOUSE
NC score	0.032661 (rank : 130)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	232	Target Neighborhood Hits	1187	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.032649 (rank : 131)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	232	Target Neighborhood Hits	1186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

ZO1_HUMAN
NC score	0.032409 (rank : 132)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	232	Target Neighborhood Hits	474	Shared Neighborhood Hits	41
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PEPL_HUMAN
NC score	0.031597 (rank : 133)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	232	Target Neighborhood Hits	1141	Shared Neighborhood Hits	54
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
NC score	0.031567 (rank : 134)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	232	Target Neighborhood Hits	1105	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

NUMA1_HUMAN
NC score	0.031252 (rank : 135)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	232	Target Neighborhood Hits	1523	Shared Neighborhood Hits	72
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

IF2P_HUMAN
NC score	0.030627 (rank : 136)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	232	Target Neighborhood Hits	889	Shared Neighborhood Hits	52
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SPEG_MOUSE
NC score	0.030142 (rank : 137)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	232	Target Neighborhood Hits	1959	Shared Neighborhood Hits	78
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CCD96_MOUSE
NC score	0.029991 (rank : 138)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	232	Target Neighborhood Hits	704	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

MYPT2_HUMAN
NC score	0.029566 (rank : 139)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	232	Target Neighborhood Hits	707	Shared Neighborhood Hits	40
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

CDA7L_MOUSE
NC score	0.029437 (rank : 140)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	232	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q922M5	Gene names	Cdca7l
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Transcription factor RAM2).

ZN638_MOUSE
NC score	0.029415 (rank : 141)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	232	Target Neighborhood Hits	318	Shared Neighborhood Hits	29
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

DEK_HUMAN
NC score	0.029372 (rank : 142)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	232	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

BRD8_MOUSE
NC score	0.029189 (rank : 143)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	232	Target Neighborhood Hits	422	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

LAP2_MOUSE
NC score	0.028767 (rank : 144)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	232	Target Neighborhood Hits	482	Shared Neighborhood Hits	17
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SMC2_MOUSE
NC score	0.028655 (rank : 145)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	232	Target Neighborhood Hits	1131	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

OPTN_MOUSE
NC score	0.028542 (rank : 146)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	232	Target Neighborhood Hits	1120	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

DESP_HUMAN
NC score	0.028109 (rank : 147)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	232	Target Neighborhood Hits	1470	Shared Neighborhood Hits	72
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

AP3B1_MOUSE
NC score	0.028083 (rank : 148)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	232	Target Neighborhood Hits	302	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

LY10_HUMAN
NC score	0.028066 (rank : 149)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	232	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SPEG_HUMAN
NC score	0.028009 (rank : 150)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	232	Target Neighborhood Hits	1762	Shared Neighborhood Hits	60
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PLEC1_HUMAN
NC score	0.027609 (rank : 151)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	232	Target Neighborhood Hits	1326	Shared Neighborhood Hits	53
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

ATF2_HUMAN
NC score	0.027489 (rank : 152)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	232	Target Neighborhood Hits	402	Shared Neighborhood Hits	29
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

AUTS2_HUMAN
NC score	0.027449 (rank : 153)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	232	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

ATF2_MOUSE
NC score	0.027412 (rank : 154)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	232	Target Neighborhood Hits	397	Shared Neighborhood Hits	28
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

CO002_HUMAN
NC score	0.027387 (rank : 155)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	232	Target Neighborhood Hits	387	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

MYPT1_MOUSE
NC score	0.026953 (rank : 156)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	232	Target Neighborhood Hits	539	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

SDC3_MOUSE
NC score	0.026926 (rank : 157)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	232	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

RIMB1_MOUSE
NC score	0.026594 (rank : 158)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	232	Target Neighborhood Hits	1376	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

EP400_HUMAN
NC score	0.026314 (rank : 159)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	232	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

M6PBP_MOUSE
NC score	0.026293 (rank : 160)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	232	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBG5, Q3TK05, Q8BKV9, Q9CZK1	Gene names	M6prbp1, Tip47
Domain Architecture	No domain graphic available
Description	Mannose-6-phosphate receptor-binding protein 1 (Cargo selection protein TIP47).

PHAR3_HUMAN
NC score	0.026288 (rank : 161)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	232	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

K1802_MOUSE
NC score	0.026263 (rank : 162)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	232	Target Neighborhood Hits	1596	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

EVL_HUMAN
NC score	0.026099 (rank : 163)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	232	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

CCAR1_HUMAN
NC score	0.025833 (rank : 164)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	232	Target Neighborhood Hits	444	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

ZC3H6_MOUSE
NC score	0.025722 (rank : 165)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	232	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

NRG2_HUMAN
NC score	0.025270 (rank : 166)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	232	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

LYSM2_HUMAN
NC score	0.025140 (rank : 167)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	232	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IV50, Q5CZ88, Q8WTV3	Gene names	LYSMD2
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 2.

SDC3_HUMAN
NC score	0.024960 (rank : 168)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	232	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

APC_MOUSE
NC score	0.024485 (rank : 169)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	232	Target Neighborhood Hits	441	Shared Neighborhood Hits	34
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ARS2_MOUSE
NC score	0.023925 (rank : 170)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	232	Target Neighborhood Hits	212	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

SENP7_HUMAN
NC score	0.023856 (rank : 171)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	232	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

PHAR3_MOUSE
NC score	0.023850 (rank : 172)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	232	Target Neighborhood Hits	206	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

BAZ2A_MOUSE
NC score	0.023532 (rank : 173)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	232	Target Neighborhood Hits	744	Shared Neighborhood Hits	52
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BPAEA_HUMAN
NC score	0.023451 (rank : 174)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	232	Target Neighborhood Hits	1369	Shared Neighborhood Hits	57
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

FA44A_HUMAN
NC score	0.022157 (rank : 175)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	232	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

GCC1_HUMAN
NC score	0.021939 (rank : 176)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	232	Target Neighborhood Hits	887	Shared Neighborhood Hits	42
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TEX2_MOUSE
NC score	0.021451 (rank : 177)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	232	Target Neighborhood Hits	121	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ATX2L_HUMAN
NC score	0.020847 (rank : 178)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	232	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CRTC1_MOUSE
NC score	0.020743 (rank : 179)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	232	Target Neighborhood Hits	230	Shared Neighborhood Hits	22
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

SYMPK_HUMAN
NC score	0.020696 (rank : 180)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	232	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

TITIN_HUMAN
NC score	0.020603 (rank : 181)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	232	Target Neighborhood Hits	2923	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GCC1_MOUSE
NC score	0.020206 (rank : 182)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	232	Target Neighborhood Hits	777	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

JHD2C_MOUSE
NC score	0.020043 (rank : 183)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	232	Target Neighborhood Hits	297	Shared Neighborhood Hits	32
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

TRA2A_HUMAN
NC score	0.019784 (rank : 184)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	232	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q13595	Gene names	TRA2A
Domain Architecture
Description	Transformer-2 protein homolog (TRA-2 alpha).

ERCC5_HUMAN
NC score	0.019611 (rank : 185)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	232	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

TTBK2_MOUSE
NC score	0.019318 (rank : 186)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	232	Target Neighborhood Hits	811	Shared Neighborhood Hits	33
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

GOGA2_HUMAN
NC score	0.018599 (rank : 187)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	232	Target Neighborhood Hits	856	Shared Neighborhood Hits	34
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

SYMPK_MOUSE
NC score	0.018416 (rank : 188)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	232	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

NOL7_HUMAN
NC score	0.018083 (rank : 189)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	232	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMY1, Q5T297, Q9Y3U7	Gene names	NOL7, C6orf90, NOP27
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7 (Nucleolar protein of 27 kDa).

PHAR1_MOUSE
NC score	0.017762 (rank : 190)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	232	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

PHAR1_HUMAN
NC score	0.017749 (rank : 191)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	232	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

CD2L7_HUMAN
NC score	0.017661 (rank : 192)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	232	Target Neighborhood Hits	1275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CT116_HUMAN
NC score	0.016877 (rank : 193)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	232	Target Neighborhood Hits	294	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CS029_MOUSE
NC score	0.016640 (rank : 194)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	232	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CD2L1_MOUSE
NC score	0.016548 (rank : 195)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	232	Target Neighborhood Hits	1463	Shared Neighborhood Hits	61
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

MYPN_MOUSE
NC score	0.016294 (rank : 196)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	232	Target Neighborhood Hits	421	Shared Neighborhood Hits	22
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

PSD3_HUMAN
NC score	0.016260 (rank : 197)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	232	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

BRE1A_HUMAN
NC score	0.016096 (rank : 198)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	232	Target Neighborhood Hits	1071	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

MOK_HUMAN
NC score	0.015522 (rank : 199)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	232	Target Neighborhood Hits	807	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ07, Q92790, Q93067	Gene names	RAGE, MOK, RAGE1
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1).

TPM1_MOUSE
NC score	0.015494 (rank : 200)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	232	Target Neighborhood Hits	729	Shared Neighborhood Hits	37
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_HUMAN
NC score	0.015472 (rank : 201)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	232	Target Neighborhood Hits	716	Shared Neighborhood Hits	37
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

SURF6_HUMAN
NC score	0.015262 (rank : 202)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	232	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	O75683, Q9BRK9, Q9BTZ5, Q9UK24	Gene names	SURF6, SURF-6
Domain Architecture
Description	Surfeit locus protein 6.

HDGF_MOUSE
NC score	0.015227 (rank : 203)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	232	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

MCM2_HUMAN
NC score	0.015021 (rank : 204)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	232	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

ANR47_HUMAN
NC score	0.014990 (rank : 205)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	232	Target Neighborhood Hits	369	Shared Neighborhood Hits	14
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

RADI_HUMAN
NC score	0.014941 (rank : 206)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	232	Target Neighborhood Hits	741	Shared Neighborhood Hits	40
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

NRG2_MOUSE
NC score	0.014931 (rank : 207)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	232	Target Neighborhood Hits	392	Shared Neighborhood Hits	8
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

CD2L1_HUMAN
NC score	0.014763 (rank : 208)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	232	Target Neighborhood Hits	1467	Shared Neighborhood Hits	58
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

MYRIP_MOUSE
NC score	0.014622 (rank : 209)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	232	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

DDX46_MOUSE
NC score	0.014582 (rank : 210)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	232	Target Neighborhood Hits	358	Shared Neighborhood Hits	31
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

CE110_MOUSE
NC score	0.014498 (rank : 211)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	232	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

STK23_MOUSE
NC score	0.014410 (rank : 212)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	232	Target Neighborhood Hits	572	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0G2	Gene names	Stk23, Mssk1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

PZRN3_HUMAN
NC score	0.014065 (rank : 213)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	232	Target Neighborhood Hits	461	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RADI_MOUSE
NC score	0.013549 (rank : 214)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	232	Target Neighborhood Hits	773	Shared Neighborhood Hits	38
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

WDR74_HUMAN
NC score	0.013545 (rank : 215)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	232	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

PZRN3_MOUSE
NC score	0.012950 (rank : 216)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	232	Target Neighborhood Hits	447	Shared Neighborhood Hits	19
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

CHD6_HUMAN
NC score	0.012792 (rank : 217)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	232	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

MCM2_MOUSE
NC score	0.012715 (rank : 218)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	232	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

DNJC1_HUMAN
NC score	0.011737 (rank : 219)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	232	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KC8	Gene names	DNAJC1
Domain Architecture
Description	DnaJ homolog subfamily C member 1.

ZEP2_MOUSE
NC score	0.011730 (rank : 220)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	232	Target Neighborhood Hits	964	Shared Neighborhood Hits	43
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

MK07_HUMAN
NC score	0.011374 (rank : 221)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	232	Target Neighborhood Hits	1087	Shared Neighborhood Hits	41
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

X3CL1_HUMAN
NC score	0.011161 (rank : 222)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	232	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ANK1_HUMAN
NC score	0.010900 (rank : 223)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	232	Target Neighborhood Hits	416	Shared Neighborhood Hits	21
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

NCOA1_HUMAN
NC score	0.009529 (rank : 224)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	232	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

TNIK_HUMAN
NC score	0.009302 (rank : 225)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	232	Target Neighborhood Hits	1570	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TLE1_MOUSE
NC score	0.007739 (rank : 226)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	232	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

PRKDC_MOUSE
NC score	0.007613 (rank : 227)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	232	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

FGD1_HUMAN
NC score	0.006676 (rank : 228)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	232	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

BLM_HUMAN
NC score	0.006554 (rank : 229)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	232	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

MARK4_MOUSE
NC score	0.006503 (rank : 230)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	232	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

SOX14_MOUSE
NC score	0.006410 (rank : 231)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	232	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

MARK4_HUMAN
NC score	0.006250 (rank : 232)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	232	Target Neighborhood Hits	886	Shared Neighborhood Hits	24
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

PDGFD_HUMAN
NC score	0.005880 (rank : 233)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	232	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

DC1I2_HUMAN
NC score	0.005654 (rank : 234)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	232	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

UBP21_HUMAN
NC score	0.005624 (rank : 235)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	232	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

SOX14_HUMAN
NC score	0.005060 (rank : 236)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	232	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

PRL_HUMAN
NC score	0.004706 (rank : 237)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	232	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P01236, Q15199, Q92996	Gene names	PRL
Domain Architecture
Description	Prolactin precursor (PRL).

IRAK1_HUMAN
NC score	0.004351 (rank : 238)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	232	Target Neighborhood Hits	820	Shared Neighborhood Hits	21
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

SIGL9_HUMAN
NC score	0.004292 (rank : 239)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	232	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

PDE3A_HUMAN
NC score	0.004238 (rank : 240)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	232	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

RARG1_HUMAN
NC score	0.003855 (rank : 241)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	232	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
NC score	0.003823 (rank : 242)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	232	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG1_MOUSE
NC score	0.003774 (rank : 243)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	232	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
NC score	0.003739 (rank : 244)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	232	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

ZN438_HUMAN
NC score	0.003447 (rank : 245)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	232	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ABL1_HUMAN
NC score	0.003155 (rank : 246)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	232	Target Neighborhood Hits	1220	Shared Neighborhood Hits	36
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ZBT38_HUMAN
NC score	0.002081 (rank : 247)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	232	Target Neighborhood Hits	885	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

PCDH7_HUMAN
NC score	0.001095 (rank : 248)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	232	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

ZNF18_HUMAN
NC score	-0.001311 (rank : 249)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	232	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	P17022, Q5QHQ3, Q8IYC4, Q8NAH6	Gene names	ZNF18, HDSG1, KOX11
Domain Architecture	No domain graphic available
Description	Zinc finger protein 18 (Zinc finger protein KOX11) (Heart development- specific gene 1 protein).

ZN202_HUMAN
NC score	-0.002110 (rank : 250)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	232	Target Neighborhood Hits	756	Shared Neighborhood Hits	16
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

ZBT16_HUMAN
NC score	-0.002241 (rank : 251)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	232	Target Neighborhood Hits	1010	Shared Neighborhood Hits	20
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZN282_HUMAN
NC score	-0.002613 (rank : 252)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	232	Target Neighborhood Hits	796	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).