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Network neighborhood for query Sequence : ANK1_MOUSE

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ANK1_MOUSE
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ANK1_HUMAN
θ value	0 (rank : 1)	NC score	0.996190 (rank : 2)
Query Neighborhood Hits	430	Target Neighborhood Hits	416	Shared Neighborhood Hits	358
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	430	Target Neighborhood Hits	430	Shared Neighborhood Hits	430
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK2_HUMAN
θ value	0 (rank : 3)	NC score	0.917591 (rank : 25)
Query Neighborhood Hits	430	Target Neighborhood Hits	1615	Shared Neighborhood Hits	368
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
θ value	0 (rank : 4)	NC score	0.975361 (rank : 3)
Query Neighborhood Hits	430	Target Neighborhood Hits	853	Shared Neighborhood Hits	347
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR44_HUMAN
θ value	6.71607e-88 (rank : 5)	NC score	0.954921 (rank : 5)
Query Neighborhood Hits	430	Target Neighborhood Hits	318	Shared Neighborhood Hits	311
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
θ value	9.69798e-87 (rank : 6)	NC score	0.953409 (rank : 6)
Query Neighborhood Hits	430	Target Neighborhood Hits	314	Shared Neighborhood Hits	307
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
θ value	1.65422e-86 (rank : 7)	NC score	0.952537 (rank : 7)
Query Neighborhood Hits	430	Target Neighborhood Hits	314	Shared Neighborhood Hits	307
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR50_HUMAN
θ value	8.20983e-86 (rank : 8)	NC score	0.958273 (rank : 4)
Query Neighborhood Hits	430	Target Neighborhood Hits	361	Shared Neighborhood Hits	307
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS2_HUMAN
θ value	2.0926e-81 (rank : 9)	NC score	0.944721 (rank : 10)
Query Neighborhood Hits	430	Target Neighborhood Hits	361	Shared Neighborhood Hits	310
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
θ value	2.73302e-81 (rank : 10)	NC score	0.944253 (rank : 11)
Query Neighborhood Hits	430	Target Neighborhood Hits	477	Shared Neighborhood Hits	314
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR52_MOUSE
θ value	1.35638e-80 (rank : 11)	NC score	0.949879 (rank : 8)
Query Neighborhood Hits	430	Target Neighborhood Hits	318	Shared Neighborhood Hits	309
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
θ value	6.73165e-80 (rank : 12)	NC score	0.949732 (rank : 9)
Query Neighborhood Hits	430	Target Neighborhood Hits	322	Shared Neighborhood Hits	309
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANKK1_HUMAN
θ value	6.99855e-61 (rank : 13)	NC score	0.609018 (rank : 206)
Query Neighborhood Hits	430	Target Neighborhood Hits	1075	Shared Neighborhood Hits	308
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANKK1_MOUSE
θ value	2.03627e-60 (rank : 14)	NC score	0.594557 (rank : 211)
Query Neighborhood Hits	430	Target Neighborhood Hits	1072	Shared Neighborhood Hits	305
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

INVS_MOUSE
θ value	8.57503e-51 (rank : 15)	NC score	0.922114 (rank : 22)
Query Neighborhood Hits	430	Target Neighborhood Hits	609	Shared Neighborhood Hits	303
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANFY1_HUMAN
θ value	4.70527e-49 (rank : 16)	NC score	0.845906 (rank : 114)
Query Neighborhood Hits	430	Target Neighborhood Hits	480	Shared Neighborhood Hits	297
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

TRPA1_HUMAN
θ value	1.04822e-48 (rank : 17)	NC score	0.924702 (rank : 21)
Query Neighborhood Hits	430	Target Neighborhood Hits	339	Shared Neighborhood Hits	306
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANFY1_MOUSE
θ value	1.36902e-48 (rank : 18)	NC score	0.846966 (rank : 113)
Query Neighborhood Hits	430	Target Neighborhood Hits	480	Shared Neighborhood Hits	305
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

RIPK4_HUMAN
θ value	1.51363e-47 (rank : 19)	NC score	0.595884 (rank : 209)
Query Neighborhood Hits	430	Target Neighborhood Hits	1094	Shared Neighborhood Hits	313
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

INVS_HUMAN
θ value	7.51208e-47 (rank : 20)	NC score	0.930230 (rank : 16)
Query Neighborhood Hits	430	Target Neighborhood Hits	455	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

TRPA1_MOUSE
θ value	4.122e-45 (rank : 21)	NC score	0.925347 (rank : 20)
Query Neighborhood Hits	430	Target Neighborhood Hits	343	Shared Neighborhood Hits	302
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

DAPK1_MOUSE
θ value	6.37413e-38 (rank : 22)	NC score	0.425012 (rank : 257)
Query Neighborhood Hits	430	Target Neighborhood Hits	1138	Shared Neighborhood Hits	312
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TNI3K_HUMAN
θ value	8.32485e-38 (rank : 23)	NC score	0.474357 (rank : 247)
Query Neighborhood Hits	430	Target Neighborhood Hits	1084	Shared Neighborhood Hits	307
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ASB2_HUMAN
θ value	5.39604e-37 (rank : 24)	NC score	0.920671 (rank : 24)
Query Neighborhood Hits	430	Target Neighborhood Hits	309	Shared Neighborhood Hits	295
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_MOUSE
θ value	1.57e-36 (rank : 25)	NC score	0.932282 (rank : 15)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	298
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_HUMAN
θ value	4.568e-36 (rank : 26)	NC score	0.933487 (rank : 14)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TNI3K_MOUSE
θ value	4.568e-36 (rank : 27)	NC score	0.468394 (rank : 248)
Query Neighborhood Hits	430	Target Neighborhood Hits	1079	Shared Neighborhood Hits	308
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

DAPK1_HUMAN
θ value	6.59618e-35 (rank : 28)	NC score	0.415090 (rank : 263)
Query Neighborhood Hits	430	Target Neighborhood Hits	1130	Shared Neighborhood Hits	306
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ASB2_MOUSE
θ value	1.12514e-34 (rank : 29)	NC score	0.914852 (rank : 28)
Query Neighborhood Hits	430	Target Neighborhood Hits	321	Shared Neighborhood Hits	292
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB15_HUMAN
θ value	1.46948e-34 (rank : 30)	NC score	0.900636 (rank : 36)
Query Neighborhood Hits	430	Target Neighborhood Hits	305	Shared Neighborhood Hits	287
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB15_MOUSE
θ value	2.12192e-33 (rank : 31)	NC score	0.889212 (rank : 55)
Query Neighborhood Hits	430	Target Neighborhood Hits	292	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR42_MOUSE
θ value	3.61944e-33 (rank : 32)	NC score	0.920677 (rank : 23)
Query Neighborhood Hits	430	Target Neighborhood Hits	334	Shared Neighborhood Hits	285
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

MIB1_HUMAN
θ value	1.0531e-32 (rank : 33)	NC score	0.876785 (rank : 64)
Query Neighborhood Hits	430	Target Neighborhood Hits	470	Shared Neighborhood Hits	306
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.0531e-32 (rank : 34)	NC score	0.876444 (rank : 65)
Query Neighborhood Hits	430	Target Neighborhood Hits	471	Shared Neighborhood Hits	306
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANR29_HUMAN
θ value	2.34606e-32 (rank : 35)	NC score	0.939306 (rank : 12)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	294
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANKS6_MOUSE
θ value	4.00176e-32 (rank : 36)	NC score	0.897453 (rank : 40)
Query Neighborhood Hits	430	Target Neighborhood Hits	435	Shared Neighborhood Hits	298
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKR6_HUMAN
θ value	4.42448e-31 (rank : 37)	NC score	0.925913 (rank : 19)
Query Neighborhood Hits	430	Target Neighborhood Hits	439	Shared Neighborhood Hits	300
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR16_HUMAN
θ value	4.42448e-31 (rank : 38)	NC score	0.938737 (rank : 13)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	283
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANKS1_MOUSE
θ value	8.3442e-30 (rank : 39)	NC score	0.869599 (rank : 77)
Query Neighborhood Hits	430	Target Neighborhood Hits	453	Shared Neighborhood Hits	303
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

CSKI1_HUMAN
θ value	4.14116e-29 (rank : 40)	NC score	0.840975 (rank : 119)
Query Neighborhood Hits	430	Target Neighborhood Hits	997	Shared Neighborhood Hits	307
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	7.06379e-29 (rank : 41)	NC score	0.839473 (rank : 121)
Query Neighborhood Hits	430	Target Neighborhood Hits	1031	Shared Neighborhood Hits	310
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB10_MOUSE
θ value	1.2049e-28 (rank : 42)	NC score	0.915576 (rank : 26)
Query Neighborhood Hits	430	Target Neighborhood Hits	301	Shared Neighborhood Hits	287
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANKS6_HUMAN
θ value	2.68423e-28 (rank : 43)	NC score	0.896744 (rank : 41)
Query Neighborhood Hits	430	Target Neighborhood Hits	411	Shared Neighborhood Hits	299
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

EHMT1_HUMAN
θ value	2.68423e-28 (rank : 44)	NC score	0.849371 (rank : 107)
Query Neighborhood Hits	430	Target Neighborhood Hits	417	Shared Neighborhood Hits	309
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

CSKI2_HUMAN
θ value	3.50572e-28 (rank : 45)	NC score	0.852171 (rank : 103)
Query Neighborhood Hits	430	Target Neighborhood Hits	747	Shared Neighborhood Hits	307
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB10_HUMAN
θ value	5.97985e-28 (rank : 46)	NC score	0.915523 (rank : 27)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CSKI2_MOUSE
θ value	7.80994e-28 (rank : 47)	NC score	0.852819 (rank : 102)
Query Neighborhood Hits	430	Target Neighborhood Hits	812	Shared Neighborhood Hits	302
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

EHMT2_MOUSE
θ value	8.63488e-27 (rank : 48)	NC score	0.823321 (rank : 129)
Query Neighborhood Hits	430	Target Neighborhood Hits	750	Shared Neighborhood Hits	315
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANKS1_HUMAN
θ value	2.51237e-26 (rank : 49)	NC score	0.880481 (rank : 62)
Query Neighborhood Hits	430	Target Neighborhood Hits	438	Shared Neighborhood Hits	308
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

EHMT2_HUMAN
θ value	3.28125e-26 (rank : 50)	NC score	0.838987 (rank : 122)
Query Neighborhood Hits	430	Target Neighborhood Hits	498	Shared Neighborhood Hits	311
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MIB2_HUMAN
θ value	5.59698e-26 (rank : 51)	NC score	0.865780 (rank : 88)
Query Neighborhood Hits	430	Target Neighborhood Hits	438	Shared Neighborhood Hits	294
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB14_MOUSE
θ value	1.24688e-25 (rank : 52)	NC score	0.885079 (rank : 60)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANR42_HUMAN
θ value	2.77775e-25 (rank : 53)	NC score	0.914235 (rank : 31)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB13_HUMAN
θ value	3.62785e-25 (rank : 54)	NC score	0.905261 (rank : 34)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	3.62785e-25 (rank : 55)	NC score	0.905274 (rank : 33)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

PSD10_MOUSE
θ value	3.62785e-25 (rank : 56)	NC score	0.927881 (rank : 18)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_HUMAN
θ value	4.73814e-25 (rank : 57)	NC score	0.929071 (rank : 17)
Query Neighborhood Hits	430	Target Neighborhood Hits	301	Shared Neighborhood Hits	297
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MIB2_MOUSE
θ value	1.37858e-24 (rank : 58)	NC score	0.866238 (rank : 85)
Query Neighborhood Hits	430	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ASB16_MOUSE
θ value	3.07116e-24 (rank : 59)	NC score	0.891743 (rank : 50)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	285
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

PA2G6_HUMAN
θ value	5.23862e-24 (rank : 60)	NC score	0.890818 (rank : 52)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	282
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	5.23862e-24 (rank : 61)	NC score	0.896024 (rank : 45)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	291
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB5_HUMAN
θ value	6.84181e-24 (rank : 62)	NC score	0.873421 (rank : 68)
Query Neighborhood Hits	430	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
θ value	8.93572e-24 (rank : 63)	NC score	0.871007 (rank : 75)
Query Neighborhood Hits	430	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

RN5A_MOUSE
θ value	8.93572e-24 (rank : 64)	NC score	0.806168 (rank : 134)
Query Neighborhood Hits	430	Target Neighborhood Hits	899	Shared Neighborhood Hits	308
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CTTB2_HUMAN
θ value	3.39556e-23 (rank : 65)	NC score	0.780427 (rank : 145)
Query Neighborhood Hits	430	Target Neighborhood Hits	1061	Shared Neighborhood Hits	313
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

RAI14_MOUSE
θ value	5.79196e-23 (rank : 66)	NC score	0.635752 (rank : 197)
Query Neighborhood Hits	430	Target Neighborhood Hits	1505	Shared Neighborhood Hits	334
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

PP16A_MOUSE
θ value	9.87957e-23 (rank : 67)	NC score	0.879411 (rank : 63)
Query Neighborhood Hits	430	Target Neighborhood Hits	318	Shared Neighborhood Hits	286
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

NOTC4_MOUSE
θ value	1.29031e-22 (rank : 68)	NC score	0.487845 (rank : 243)
Query Neighborhood Hits	430	Target Neighborhood Hits	872	Shared Neighborhood Hits	291
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB7_HUMAN
θ value	3.75424e-22 (rank : 69)	NC score	0.914710 (rank : 30)
Query Neighborhood Hits	430	Target Neighborhood Hits	296	Shared Neighborhood Hits	288
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	3.75424e-22 (rank : 70)	NC score	0.914808 (rank : 29)
Query Neighborhood Hits	430	Target Neighborhood Hits	296	Shared Neighborhood Hits	288
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR35_HUMAN
θ value	4.9032e-22 (rank : 71)	NC score	0.832783 (rank : 128)
Query Neighborhood Hits	430	Target Neighborhood Hits	784	Shared Neighborhood Hits	307
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB11_HUMAN
θ value	4.9032e-22 (rank : 72)	NC score	0.869443 (rank : 79)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

RAI14_HUMAN
θ value	4.9032e-22 (rank : 73)	NC score	0.671628 (rank : 189)
Query Neighborhood Hits	430	Target Neighborhood Hits	1367	Shared Neighborhood Hits	327
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ASB11_MOUSE
θ value	6.40375e-22 (rank : 74)	NC score	0.868808 (rank : 81)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MYPT1_MOUSE
θ value	8.36355e-22 (rank : 75)	NC score	0.869213 (rank : 80)
Query Neighborhood Hits	430	Target Neighborhood Hits	539	Shared Neighborhood Hits	299
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PP16A_HUMAN
θ value	8.36355e-22 (rank : 76)	NC score	0.873231 (rank : 70)
Query Neighborhood Hits	430	Target Neighborhood Hits	340	Shared Neighborhood Hits	281
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_HUMAN
θ value	1.09232e-21 (rank : 77)	NC score	0.868311 (rank : 83)
Query Neighborhood Hits	430	Target Neighborhood Hits	307	Shared Neighborhood Hits	283
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB9_HUMAN
θ value	1.42661e-21 (rank : 78)	NC score	0.873263 (rank : 69)
Query Neighborhood Hits	430	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB9_MOUSE
θ value	1.42661e-21 (rank : 79)	NC score	0.863277 (rank : 92)
Query Neighborhood Hits	430	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

BCL3_HUMAN
θ value	3.17815e-21 (rank : 80)	NC score	0.895383 (rank : 46)
Query Neighborhood Hits	430	Target Neighborhood Hits	324	Shared Neighborhood Hits	294
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

MYPT1_HUMAN
θ value	5.42112e-21 (rank : 81)	NC score	0.848753 (rank : 108)
Query Neighborhood Hits	430	Target Neighborhood Hits	723	Shared Neighborhood Hits	310
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

PP16B_MOUSE
θ value	5.42112e-21 (rank : 82)	NC score	0.866229 (rank : 86)
Query Neighborhood Hits	430	Target Neighborhood Hits	302	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR23_MOUSE
θ value	9.24701e-21 (rank : 83)	NC score	0.900141 (rank : 37)
Query Neighborhood Hits	430	Target Neighborhood Hits	296	Shared Neighborhood Hits	291
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

NOTC4_HUMAN
θ value	1.2077e-20 (rank : 84)	NC score	0.481114 (rank : 246)
Query Neighborhood Hits	430	Target Neighborhood Hits	905	Shared Neighborhood Hits	294
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANKR1_HUMAN
θ value	1.5773e-20 (rank : 85)	NC score	0.894330 (rank : 47)
Query Neighborhood Hits	430	Target Neighborhood Hits	308	Shared Neighborhood Hits	286
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

FANK1_HUMAN
θ value	1.5773e-20 (rank : 86)	NC score	0.906627 (rank : 32)
Query Neighborhood Hits	430	Target Neighborhood Hits	326	Shared Neighborhood Hits	290
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

BCL3_MOUSE
θ value	7.82807e-20 (rank : 87)	NC score	0.888691 (rank : 56)
Query Neighborhood Hits	430	Target Neighborhood Hits	388	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANR23_HUMAN
θ value	1.02238e-19 (rank : 88)	NC score	0.899101 (rank : 38)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	288
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANKR2_MOUSE
θ value	1.33526e-19 (rank : 89)	NC score	0.896404 (rank : 43)
Query Neighborhood Hits	430	Target Neighborhood Hits	312	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

MYPT2_HUMAN
θ value	1.33526e-19 (rank : 90)	NC score	0.853220 (rank : 100)
Query Neighborhood Hits	430	Target Neighborhood Hits	707	Shared Neighborhood Hits	302
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB4_HUMAN
θ value	1.74391e-19 (rank : 91)	NC score	0.864995 (rank : 91)
Query Neighborhood Hits	430	Target Neighborhood Hits	264	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANKR5_HUMAN
θ value	2.27762e-19 (rank : 92)	NC score	0.876418 (rank : 66)
Query Neighborhood Hits	430	Target Neighborhood Hits	297	Shared Neighborhood Hits	285
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

NOTC2_HUMAN
θ value	2.97466e-19 (rank : 93)	NC score	0.435524 (rank : 255)
Query Neighborhood Hits	430	Target Neighborhood Hits	1113	Shared Neighborhood Hits	292
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RN5A_HUMAN
θ value	2.97466e-19 (rank : 94)	NC score	0.855867 (rank : 97)
Query Neighborhood Hits	430	Target Neighborhood Hits	608	Shared Neighborhood Hits	290
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

NFKB1_MOUSE
θ value	3.88503e-19 (rank : 95)	NC score	0.772196 (rank : 150)
Query Neighborhood Hits	430	Target Neighborhood Hits	300	Shared Neighborhood Hits	275
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

GABP2_HUMAN
θ value	5.07402e-19 (rank : 96)	NC score	0.886562 (rank : 58)
Query Neighborhood Hits	430	Target Neighborhood Hits	454	Shared Neighborhood Hits	297
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANKR5_MOUSE
θ value	6.62687e-19 (rank : 97)	NC score	0.872340 (rank : 72)
Query Neighborhood Hits	430	Target Neighborhood Hits	298	Shared Neighborhood Hits	286
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB4_MOUSE
θ value	6.62687e-19 (rank : 98)	NC score	0.862505 (rank : 93)
Query Neighborhood Hits	430	Target Neighborhood Hits	265	Shared Neighborhood Hits	260
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANKS3_HUMAN
θ value	8.65492e-19 (rank : 99)	NC score	0.871756 (rank : 73)
Query Neighborhood Hits	430	Target Neighborhood Hits	355	Shared Neighborhood Hits	278
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANKR2_HUMAN
θ value	1.13037e-18 (rank : 100)	NC score	0.896147 (rank : 44)
Query Neighborhood Hits	430	Target Neighborhood Hits	321	Shared Neighborhood Hits	294
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

NOTC2_MOUSE
θ value	1.13037e-18 (rank : 101)	NC score	0.433216 (rank : 256)
Query Neighborhood Hits	430	Target Neighborhood Hits	1069	Shared Neighborhood Hits	293
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SHAN1_HUMAN
θ value	1.13037e-18 (rank : 102)	NC score	0.745128 (rank : 164)
Query Neighborhood Hits	430	Target Neighborhood Hits	1041	Shared Neighborhood Hits	284
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKR1_MOUSE
θ value	1.47631e-18 (rank : 103)	NC score	0.893420 (rank : 48)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	294
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

GABP2_MOUSE
θ value	1.47631e-18 (rank : 104)	NC score	0.889619 (rank : 53)
Query Neighborhood Hits	430	Target Neighborhood Hits	429	Shared Neighborhood Hits	295
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB16_HUMAN
θ value	3.28887e-18 (rank : 105)	NC score	0.884600 (rank : 61)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	274
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NOTC3_HUMAN
θ value	4.29542e-18 (rank : 106)	NC score	0.439258 (rank : 253)
Query Neighborhood Hits	430	Target Neighborhood Hits	1062	Shared Neighborhood Hits	294
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

BARD1_HUMAN
θ value	5.60996e-18 (rank : 107)	NC score	0.835604 (rank : 123)
Query Neighborhood Hits	430	Target Neighborhood Hits	427	Shared Neighborhood Hits	295
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB8_MOUSE
θ value	7.32683e-18 (rank : 108)	NC score	0.898076 (rank : 39)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

FANK1_MOUSE
θ value	7.32683e-18 (rank : 109)	NC score	0.903735 (rank : 35)
Query Neighborhood Hits	430	Target Neighborhood Hits	325	Shared Neighborhood Hits	285
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

NOTC1_HUMAN
θ value	7.32683e-18 (rank : 110)	NC score	0.437629 (rank : 254)
Query Neighborhood Hits	430	Target Neighborhood Hits	906	Shared Neighborhood Hits	288
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKS3_MOUSE
θ value	9.56915e-18 (rank : 111)	NC score	0.873698 (rank : 67)
Query Neighborhood Hits	430	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

POTE8_HUMAN
θ value	9.56915e-18 (rank : 112)	NC score	0.815878 (rank : 131)
Query Neighborhood Hits	430	Target Neighborhood Hits	337	Shared Neighborhood Hits	294
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

BARD1_MOUSE
θ value	1.24977e-17 (rank : 113)	NC score	0.834848 (rank : 125)
Query Neighborhood Hits	430	Target Neighborhood Hits	411	Shared Neighborhood Hits	288
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

NFKB1_HUMAN
θ value	1.24977e-17 (rank : 114)	NC score	0.769960 (rank : 152)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	282
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NOTC3_MOUSE
θ value	1.63225e-17 (rank : 115)	NC score	0.441813 (rank : 252)
Query Neighborhood Hits	430	Target Neighborhood Hits	975	Shared Neighborhood Hits	296
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ZDH13_HUMAN
θ value	1.63225e-17 (rank : 116)	NC score	0.777371 (rank : 147)
Query Neighborhood Hits	430	Target Neighborhood Hits	322	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

NFKB2_HUMAN
θ value	2.13179e-17 (rank : 117)	NC score	0.767220 (rank : 153)
Query Neighborhood Hits	430	Target Neighborhood Hits	325	Shared Neighborhood Hits	286
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASZ1_MOUSE
θ value	3.63628e-17 (rank : 118)	NC score	0.871684 (rank : 74)
Query Neighborhood Hits	430	Target Neighborhood Hits	319	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB8_HUMAN
θ value	6.20254e-17 (rank : 119)	NC score	0.896667 (rank : 42)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	288
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ZDH17_HUMAN
θ value	6.20254e-17 (rank : 120)	NC score	0.781268 (rank : 144)
Query Neighborhood Hits	430	Target Neighborhood Hits	334	Shared Neighborhood Hits	284
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

IKBA_HUMAN
θ value	8.10077e-17 (rank : 121)	NC score	0.861405 (rank : 95)
Query Neighborhood Hits	430	Target Neighborhood Hits	280	Shared Neighborhood Hits	278
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR11_HUMAN
θ value	1.058e-16 (rank : 122)	NC score	0.771960 (rank : 151)
Query Neighborhood Hits	430	Target Neighborhood Hits	1289	Shared Neighborhood Hits	307
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR12_HUMAN
θ value	1.38178e-16 (rank : 123)	NC score	0.749306 (rank : 162)
Query Neighborhood Hits	430	Target Neighborhood Hits	1081	Shared Neighborhood Hits	314
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ZDH17_MOUSE
θ value	1.38178e-16 (rank : 124)	NC score	0.775930 (rank : 148)
Query Neighborhood Hits	430	Target Neighborhood Hits	328	Shared Neighborhood Hits	278
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANKR7_HUMAN
θ value	1.80466e-16 (rank : 125)	NC score	0.865847 (rank : 87)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	284
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

UACA_HUMAN
θ value	1.80466e-16 (rank : 126)	NC score	0.531407 (rank : 234)
Query Neighborhood Hits	430	Target Neighborhood Hits	1622	Shared Neighborhood Hits	329
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GABP3_MOUSE
θ value	2.35696e-16 (rank : 127)	NC score	0.885205 (rank : 59)
Query Neighborhood Hits	430	Target Neighborhood Hits	330	Shared Neighborhood Hits	281
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANR49_MOUSE
θ value	3.07829e-16 (rank : 128)	NC score	0.891313 (rank : 51)
Query Neighborhood Hits	430	Target Neighborhood Hits	285	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB12_HUMAN
θ value	3.07829e-16 (rank : 129)	NC score	0.851873 (rank : 104)
Query Neighborhood Hits	430	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASZ1_HUMAN
θ value	3.07829e-16 (rank : 130)	NC score	0.867378 (rank : 84)
Query Neighborhood Hits	430	Target Neighborhood Hits	341	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

NFKB2_MOUSE
θ value	3.07829e-16 (rank : 131)	NC score	0.752158 (rank : 161)
Query Neighborhood Hits	430	Target Neighborhood Hits	326	Shared Neighborhood Hits	283
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

UACA_MOUSE
θ value	3.07829e-16 (rank : 132)	NC score	0.504278 (rank : 240)
Query Neighborhood Hits	430	Target Neighborhood Hits	1620	Shared Neighborhood Hits	322
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ZDH13_MOUSE
θ value	5.25075e-16 (rank : 133)	NC score	0.773575 (rank : 149)
Query Neighborhood Hits	430	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR21_HUMAN
θ value	6.85773e-16 (rank : 134)	NC score	0.763621 (rank : 156)
Query Neighborhood Hits	430	Target Neighborhood Hits	864	Shared Neighborhood Hits	319
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

OSBL1_HUMAN
θ value	6.85773e-16 (rank : 135)	NC score	0.698916 (rank : 175)
Query Neighborhood Hits	430	Target Neighborhood Hits	368	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

IKBA_MOUSE
θ value	1.16975e-15 (rank : 136)	NC score	0.851685 (rank : 105)
Query Neighborhood Hits	430	Target Neighborhood Hits	283	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

POT15_HUMAN
θ value	1.52774e-15 (rank : 137)	NC score	0.764819 (rank : 155)
Query Neighborhood Hits	430	Target Neighborhood Hits	893	Shared Neighborhood Hits	320
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

OSBL1_MOUSE
θ value	1.99529e-15 (rank : 138)	NC score	0.687026 (rank : 186)
Query Neighborhood Hits	430	Target Neighborhood Hits	336	Shared Neighborhood Hits	286
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

A20A3_HUMAN
θ value	2.60593e-15 (rank : 139)	NC score	0.697778 (rank : 178)
Query Neighborhood Hits	430	Target Neighborhood Hits	692	Shared Neighborhood Hits	285
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	2.60593e-15 (rank : 140)	NC score	0.693000 (rank : 184)
Query Neighborhood Hits	430	Target Neighborhood Hits	710	Shared Neighborhood Hits	286
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR19_HUMAN
θ value	2.60593e-15 (rank : 141)	NC score	0.810729 (rank : 133)
Query Neighborhood Hits	430	Target Neighborhood Hits	276	Shared Neighborhood Hits	274
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR39_HUMAN
θ value	2.60593e-15 (rank : 142)	NC score	0.892635 (rank : 49)
Query Neighborhood Hits	430	Target Neighborhood Hits	285	Shared Neighborhood Hits	283
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR49_HUMAN
θ value	2.60593e-15 (rank : 143)	NC score	0.886725 (rank : 57)
Query Neighborhood Hits	430	Target Neighborhood Hits	282	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

A20A1_HUMAN
θ value	3.40345e-15 (rank : 144)	NC score	0.696004 (rank : 180)
Query Neighborhood Hits	430	Target Neighborhood Hits	698	Shared Neighborhood Hits	286
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	3.40345e-15 (rank : 145)	NC score	0.697275 (rank : 179)
Query Neighborhood Hits	430	Target Neighborhood Hits	716	Shared Neighborhood Hits	288
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANR10_HUMAN
θ value	3.40345e-15 (rank : 146)	NC score	0.857423 (rank : 96)
Query Neighborhood Hits	430	Target Neighborhood Hits	289	Shared Neighborhood Hits	269
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB12_MOUSE
θ value	3.40345e-15 (rank : 147)	NC score	0.847463 (rank : 112)
Query Neighborhood Hits	430	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR39_MOUSE
θ value	5.8054e-15 (rank : 148)	NC score	0.889575 (rank : 54)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

PIDD_HUMAN
θ value	5.8054e-15 (rank : 149)	NC score	0.095871 (rank : 315)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

AN36B_HUMAN
θ value	7.58209e-15 (rank : 150)	NC score	0.842122 (rank : 118)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	291
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

IKBE_MOUSE
θ value	7.58209e-15 (rank : 151)	NC score	0.855334 (rank : 98)
Query Neighborhood Hits	430	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ILK1_HUMAN
θ value	9.90251e-15 (rank : 152)	NC score	0.527883 (rank : 236)
Query Neighborhood Hits	430	Target Neighborhood Hits	857	Shared Neighborhood Hits	289
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	9.90251e-15 (rank : 153)	NC score	0.546150 (rank : 227)
Query Neighborhood Hits	430	Target Neighborhood Hits	848	Shared Neighborhood Hits	289
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

CDN2D_HUMAN
θ value	1.29331e-14 (rank : 154)	NC score	0.870688 (rank : 76)
Query Neighborhood Hits	430	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

NOTC1_MOUSE
θ value	1.68911e-14 (rank : 155)	NC score	0.373411 (rank : 269)
Query Neighborhood Hits	430	Target Neighborhood Hits	916	Shared Neighborhood Hits	267
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ILK_MOUSE
θ value	2.20605e-14 (rank : 156)	NC score	0.525445 (rank : 237)
Query Neighborhood Hits	430	Target Neighborhood Hits	858	Shared Neighborhood Hits	289
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

IKBB_MOUSE
θ value	2.88119e-14 (rank : 157)	NC score	0.833771 (rank : 127)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	281
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR26_HUMAN
θ value	3.76295e-14 (rank : 158)	NC score	0.463480 (rank : 250)
Query Neighborhood Hits	430	Target Neighborhood Hits	1614	Shared Neighborhood Hits	326
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR10_MOUSE
θ value	4.91457e-14 (rank : 159)	NC score	0.855169 (rank : 99)
Query Neighborhood Hits	430	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANRA2_HUMAN
θ value	4.91457e-14 (rank : 160)	NC score	0.852962 (rank : 101)
Query Neighborhood Hits	430	Target Neighborhood Hits	288	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR26_MOUSE
θ value	6.41864e-14 (rank : 161)	NC score	0.484207 (rank : 245)
Query Neighborhood Hits	430	Target Neighborhood Hits	1554	Shared Neighborhood Hits	323
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR18_HUMAN
θ value	8.38298e-14 (rank : 162)	NC score	0.646115 (rank : 195)
Query Neighborhood Hits	430	Target Neighborhood Hits	1106	Shared Neighborhood Hits	301
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

AN30A_HUMAN
θ value	1.09485e-13 (rank : 163)	NC score	0.607742 (rank : 207)
Query Neighborhood Hits	430	Target Neighborhood Hits	1119	Shared Neighborhood Hits	299
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

TRPV6_MOUSE
θ value	1.42992e-13 (rank : 164)	NC score	0.626228 (rank : 200)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	263
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANRA2_MOUSE
θ value	1.86753e-13 (rank : 165)	NC score	0.851634 (rank : 106)
Query Neighborhood Hits	430	Target Neighborhood Hits	287	Shared Neighborhood Hits	282
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

PIDD_MOUSE
θ value	4.16044e-13 (rank : 166)	NC score	0.092233 (rank : 316)
Query Neighborhood Hits	430	Target Neighborhood Hits	256	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

CDN2D_MOUSE
θ value	5.43371e-13 (rank : 167)	NC score	0.865672 (rank : 90)
Query Neighborhood Hits	430	Target Neighborhood Hits	267	Shared Neighborhood Hits	266
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB1_MOUSE
θ value	7.09661e-13 (rank : 168)	NC score	0.845644 (rank : 115)
Query Neighborhood Hits	430	Target Neighborhood Hits	292	Shared Neighborhood Hits	280
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

RFXK_MOUSE
θ value	7.09661e-13 (rank : 169)	NC score	0.842726 (rank : 117)
Query Neighborhood Hits	430	Target Neighborhood Hits	273	Shared Neighborhood Hits	268
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

IKBB_HUMAN
θ value	9.26847e-13 (rank : 170)	NC score	0.834984 (rank : 124)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBE_HUMAN
θ value	1.2105e-12 (rank : 171)	NC score	0.834454 (rank : 126)
Query Neighborhood Hits	430	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

CT086_HUMAN
θ value	1.58096e-12 (rank : 172)	NC score	0.872609 (rank : 71)
Query Neighborhood Hits	430	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR15_HUMAN
θ value	3.52202e-12 (rank : 173)	NC score	0.762505 (rank : 157)
Query Neighborhood Hits	430	Target Neighborhood Hits	478	Shared Neighborhood Hits	282
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

RFXK_HUMAN
θ value	3.52202e-12 (rank : 174)	NC score	0.847678 (rank : 111)
Query Neighborhood Hits	430	Target Neighborhood Hits	282	Shared Neighborhood Hits	267
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

CDN2C_HUMAN
θ value	6.00763e-12 (rank : 175)	NC score	0.869568 (rank : 78)
Query Neighborhood Hits	430	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

TRPV6_HUMAN
θ value	6.00763e-12 (rank : 176)	NC score	0.543378 (rank : 228)
Query Neighborhood Hits	430	Target Neighborhood Hits	262	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ASB1_HUMAN
θ value	1.02475e-11 (rank : 177)	NC score	0.844108 (rank : 116)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR22_HUMAN
θ value	1.33837e-11 (rank : 178)	NC score	0.848378 (rank : 109)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	243
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

TRPV5_MOUSE
θ value	2.98157e-11 (rank : 179)	NC score	0.573754 (rank : 219)
Query Neighborhood Hits	430	Target Neighborhood Hits	278	Shared Neighborhood Hits	256
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CDN2C_MOUSE
θ value	3.89403e-11 (rank : 180)	NC score	0.868609 (rank : 82)
Query Neighborhood Hits	430	Target Neighborhood Hits	270	Shared Neighborhood Hits	270
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR25_MOUSE
θ value	5.08577e-11 (rank : 181)	NC score	0.698279 (rank : 177)
Query Neighborhood Hits	430	Target Neighborhood Hits	398	Shared Neighborhood Hits	264
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASPP2_HUMAN
θ value	5.08577e-11 (rank : 182)	NC score	0.592355 (rank : 213)
Query Neighborhood Hits	430	Target Neighborhood Hits	1156	Shared Neighborhood Hits	291
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANR32_HUMAN
θ value	8.67504e-11 (rank : 183)	NC score	0.806074 (rank : 135)
Query Neighborhood Hits	430	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR25_HUMAN
θ value	1.47974e-10 (rank : 184)	NC score	0.713023 (rank : 172)
Query Neighborhood Hits	430	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

POT14_HUMAN
θ value	1.47974e-10 (rank : 185)	NC score	0.746219 (rank : 163)
Query Neighborhood Hits	430	Target Neighborhood Hits	403	Shared Neighborhood Hits	287
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

BCOR_HUMAN
θ value	1.9326e-10 (rank : 186)	NC score	0.733031 (rank : 169)
Query Neighborhood Hits	430	Target Neighborhood Hits	609	Shared Neighborhood Hits	297
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR41_HUMAN
θ value	2.52405e-10 (rank : 187)	NC score	0.803261 (rank : 136)
Query Neighborhood Hits	430	Target Neighborhood Hits	332	Shared Neighborhood Hits	257
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

BCOR_MOUSE
θ value	2.52405e-10 (rank : 188)	NC score	0.741379 (rank : 166)
Query Neighborhood Hits	430	Target Neighborhood Hits	521	Shared Neighborhood Hits	290
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ASB6_HUMAN
θ value	3.29651e-10 (rank : 189)	NC score	0.790110 (rank : 141)
Query Neighborhood Hits	430	Target Neighborhood Hits	256	Shared Neighborhood Hits	249
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

MPP8_HUMAN
θ value	4.30538e-10 (rank : 190)	NC score	0.698667 (rank : 176)
Query Neighborhood Hits	430	Target Neighborhood Hits	948	Shared Neighborhood Hits	285
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

TRPV5_HUMAN
θ value	4.30538e-10 (rank : 191)	NC score	0.540474 (rank : 229)
Query Neighborhood Hits	430	Target Neighborhood Hits	261	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ASB6_MOUSE
θ value	7.34386e-10 (rank : 192)	NC score	0.785802 (rank : 143)
Query Neighborhood Hits	430	Target Neighborhood Hits	264	Shared Neighborhood Hits	247
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

USH1G_HUMAN
θ value	7.34386e-10 (rank : 193)	NC score	0.792889 (rank : 140)
Query Neighborhood Hits	430	Target Neighborhood Hits	267	Shared Neighborhood Hits	260
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	7.34386e-10 (rank : 194)	NC score	0.792985 (rank : 139)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR32_MOUSE
θ value	9.59137e-10 (rank : 195)	NC score	0.795520 (rank : 138)
Query Neighborhood Hits	430	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

CENB2_HUMAN
θ value	9.59137e-10 (rank : 196)	NC score	0.570017 (rank : 220)
Query Neighborhood Hits	430	Target Neighborhood Hits	425	Shared Neighborhood Hits	254
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ANR38_HUMAN
θ value	1.63604e-09 (rank : 197)	NC score	0.694835 (rank : 182)
Query Neighborhood Hits	430	Target Neighborhood Hits	443	Shared Neighborhood Hits	252
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANS4B_HUMAN
θ value	2.13673e-09 (rank : 198)	NC score	0.788996 (rank : 142)
Query Neighborhood Hits	430	Target Neighborhood Hits	289	Shared Neighborhood Hits	261
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR38_MOUSE
θ value	2.79066e-09 (rank : 199)	NC score	0.670043 (rank : 190)
Query Neighborhood Hits	430	Target Neighborhood Hits	512	Shared Neighborhood Hits	240
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASPP1_HUMAN
θ value	3.64472e-09 (rank : 200)	NC score	0.578052 (rank : 217)
Query Neighborhood Hits	430	Target Neighborhood Hits	956	Shared Neighborhood Hits	282
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	3.64472e-09 (rank : 201)	NC score	0.559389 (rank : 221)
Query Neighborhood Hits	430	Target Neighborhood Hits	1244	Shared Neighborhood Hits	289
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ANR46_HUMAN
θ value	6.21693e-09 (rank : 202)	NC score	0.848082 (rank : 110)
Query Neighborhood Hits	430	Target Neighborhood Hits	281	Shared Neighborhood Hits	277
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR47_MOUSE
θ value	6.21693e-09 (rank : 203)	NC score	0.753792 (rank : 160)
Query Neighborhood Hits	430	Target Neighborhood Hits	350	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

MTPN_MOUSE
θ value	6.21693e-09 (rank : 204)	NC score	0.865676 (rank : 89)
Query Neighborhood Hits	430	Target Neighborhood Hits	269	Shared Neighborhood Hits	269
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

TEX14_HUMAN
θ value	6.21693e-09 (rank : 205)	NC score	0.420331 (rank : 261)
Query Neighborhood Hits	430	Target Neighborhood Hits	1103	Shared Neighborhood Hits	268
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CENB5_HUMAN
θ value	8.11959e-09 (rank : 206)	NC score	0.576396 (rank : 218)
Query Neighborhood Hits	430	Target Neighborhood Hits	395	Shared Neighborhood Hits	261
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

GIT2_MOUSE
θ value	8.11959e-09 (rank : 207)	NC score	0.553721 (rank : 223)
Query Neighborhood Hits	430	Target Neighborhood Hits	323	Shared Neighborhood Hits	255
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

SNCAP_HUMAN
θ value	1.06045e-08 (rank : 208)	NC score	0.758893 (rank : 159)
Query Neighborhood Hits	430	Target Neighborhood Hits	313	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

AN36A_HUMAN
θ value	1.38499e-08 (rank : 209)	NC score	0.799055 (rank : 137)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

MTPN_HUMAN
θ value	1.38499e-08 (rank : 210)	NC score	0.862318 (rank : 94)
Query Neighborhood Hits	430	Target Neighborhood Hits	269	Shared Neighborhood Hits	269
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANKY1_HUMAN
θ value	1.80886e-08 (rank : 211)	NC score	0.623410 (rank : 202)
Query Neighborhood Hits	430	Target Neighborhood Hits	248	Shared Neighborhood Hits	207
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

TEX14_MOUSE
θ value	1.80886e-08 (rank : 212)	NC score	0.421358 (rank : 260)
Query Neighborhood Hits	430	Target Neighborhood Hits	1333	Shared Neighborhood Hits	286
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR46_MOUSE
θ value	3.08544e-08 (rank : 213)	NC score	0.840832 (rank : 120)
Query Neighborhood Hits	430	Target Neighborhood Hits	274	Shared Neighborhood Hits	270
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR47_HUMAN
θ value	4.0297e-08 (rank : 214)	NC score	0.732843 (rank : 170)
Query Neighborhood Hits	430	Target Neighborhood Hits	369	Shared Neighborhood Hits	259
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANS4B_MOUSE
θ value	4.0297e-08 (rank : 215)	NC score	0.779738 (rank : 146)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CENB1_HUMAN
θ value	6.87365e-08 (rank : 216)	NC score	0.578691 (rank : 216)
Query Neighborhood Hits	430	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ACBD6_MOUSE
θ value	1.17247e-07 (rank : 217)	NC score	0.817125 (rank : 130)
Query Neighborhood Hits	430	Target Neighborhood Hits	305	Shared Neighborhood Hits	295
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IASPP_HUMAN
θ value	1.17247e-07 (rank : 218)	NC score	0.589231 (rank : 214)
Query Neighborhood Hits	430	Target Neighborhood Hits	688	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GIT2_HUMAN
θ value	1.53129e-07 (rank : 219)	NC score	0.513520 (rank : 239)
Query Neighborhood Hits	430	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

HECD1_HUMAN
θ value	1.53129e-07 (rank : 220)	NC score	0.623149 (rank : 203)
Query Neighborhood Hits	430	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

CDN2B_MOUSE
θ value	1.99992e-07 (rank : 221)	NC score	0.705133 (rank : 173)
Query Neighborhood Hits	430	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

GIT1_HUMAN
θ value	3.41135e-07 (rank : 222)	NC score	0.533308 (rank : 233)
Query Neighborhood Hits	430	Target Neighborhood Hits	336	Shared Neighborhood Hits	251
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	3.41135e-07 (rank : 223)	NC score	0.534602 (rank : 231)
Query Neighborhood Hits	430	Target Neighborhood Hits	341	Shared Neighborhood Hits	251
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

IASPP_MOUSE
θ value	3.41135e-07 (rank : 224)	NC score	0.533409 (rank : 232)
Query Neighborhood Hits	430	Target Neighborhood Hits	1024	Shared Neighborhood Hits	272
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KRIT1_HUMAN
θ value	3.41135e-07 (rank : 225)	NC score	0.694672 (rank : 183)
Query Neighborhood Hits	430	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	3.41135e-07 (rank : 226)	NC score	0.705116 (rank : 174)
Query Neighborhood Hits	430	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ACBD6_HUMAN
θ value	5.81887e-07 (rank : 227)	NC score	0.811325 (rank : 132)
Query Neighborhood Hits	430	Target Neighborhood Hits	304	Shared Neighborhood Hits	291
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKY2_HUMAN
θ value	5.81887e-07 (rank : 228)	NC score	0.767218 (rank : 154)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	268
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR45_HUMAN
θ value	5.81887e-07 (rank : 229)	NC score	0.621393 (rank : 205)
Query Neighborhood Hits	430	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CLPB_MOUSE
θ value	5.81887e-07 (rank : 230)	NC score	0.718534 (rank : 171)
Query Neighborhood Hits	430	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

DDEF2_MOUSE
θ value	5.81887e-07 (rank : 231)	NC score	0.420006 (rank : 262)
Query Neighborhood Hits	430	Target Neighborhood Hits	625	Shared Neighborhood Hits	238
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CD2A1_HUMAN
θ value	7.59969e-07 (rank : 232)	NC score	0.674940 (rank : 188)
Query Neighborhood Hits	430	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

DDEF2_HUMAN
θ value	7.59969e-07 (rank : 233)	NC score	0.423255 (rank : 259)
Query Neighborhood Hits	430	Target Neighborhood Hits	599	Shared Neighborhood Hits	236
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

OSTF1_HUMAN
θ value	7.59969e-07 (rank : 234)	NC score	0.647800 (rank : 194)
Query Neighborhood Hits	430	Target Neighborhood Hits	466	Shared Neighborhood Hits	257
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	7.59969e-07 (rank : 235)	NC score	0.664531 (rank : 191)
Query Neighborhood Hits	430	Target Neighborhood Hits	467	Shared Neighborhood Hits	259
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

CD2A1_MOUSE
θ value	9.92553e-07 (rank : 236)	NC score	0.735126 (rank : 168)
Query Neighborhood Hits	430	Target Neighborhood Hits	206	Shared Neighborhood Hits	203
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

DDFL1_MOUSE
θ value	9.92553e-07 (rank : 237)	NC score	0.498112 (rank : 241)
Query Neighborhood Hits	430	Target Neighborhood Hits	324	Shared Neighborhood Hits	251
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CLPB_HUMAN
θ value	2.21117e-06 (rank : 238)	NC score	0.627207 (rank : 199)
Query Neighborhood Hits	430	Target Neighborhood Hits	265	Shared Neighborhood Hits	240
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

POT22_HUMAN
θ value	2.21117e-06 (rank : 239)	NC score	0.691789 (rank : 185)
Query Neighborhood Hits	430	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ABTB2_HUMAN
θ value	2.88788e-06 (rank : 240)	NC score	0.606722 (rank : 208)
Query Neighborhood Hits	430	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR40_HUMAN
θ value	2.88788e-06 (rank : 241)	NC score	0.625281 (rank : 201)
Query Neighborhood Hits	430	Target Neighborhood Hits	224	Shared Neighborhood Hits	200
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

AN13C_HUMAN
θ value	3.77169e-06 (rank : 242)	NC score	0.551269 (rank : 226)
Query Neighborhood Hits	430	Target Neighborhood Hits	241	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANKY2_MOUSE
θ value	4.92598e-06 (rank : 243)	NC score	0.742939 (rank : 165)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	267
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR45_MOUSE
θ value	4.92598e-06 (rank : 244)	NC score	0.656876 (rank : 192)
Query Neighborhood Hits	430	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

DDEF1_MOUSE
θ value	6.43352e-06 (rank : 245)	NC score	0.325986 (rank : 281)
Query Neighborhood Hits	430	Target Neighborhood Hits	592	Shared Neighborhood Hits	198
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

LRRK1_MOUSE
θ value	6.43352e-06 (rank : 246)	NC score	0.106393 (rank : 314)
Query Neighborhood Hits	430	Target Neighborhood Hits	1267	Shared Neighborhood Hits	130
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

ANR40_MOUSE
θ value	8.40245e-06 (rank : 247)	NC score	0.621546 (rank : 204)
Query Neighborhood Hits	430	Target Neighborhood Hits	228	Shared Neighborhood Hits	205
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ABTB2_MOUSE
θ value	1.09739e-05 (rank : 248)	NC score	0.593679 (rank : 212)
Query Neighborhood Hits	430	Target Neighborhood Hits	414	Shared Neighborhood Hits	241
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

AN13A_HUMAN
θ value	1.43324e-05 (rank : 249)	NC score	0.492719 (rank : 242)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	227
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

AN13C_MOUSE
θ value	1.43324e-05 (rank : 250)	NC score	0.538331 (rank : 230)
Query Neighborhood Hits	430	Target Neighborhood Hits	242	Shared Neighborhood Hits	234
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASB14_HUMAN
θ value	1.43324e-05 (rank : 251)	NC score	0.595014 (rank : 210)
Query Neighborhood Hits	430	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

NASP_HUMAN
θ value	1.43324e-05 (rank : 252)	NC score	0.076826 (rank : 320)
Query Neighborhood Hits	430	Target Neighborhood Hits	709	Shared Neighborhood Hits	54
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

AN13B_HUMAN
θ value	1.87187e-05 (rank : 253)	NC score	0.552617 (rank : 225)
Query Neighborhood Hits	430	Target Neighborhood Hits	265	Shared Neighborhood Hits	254
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	1.87187e-05 (rank : 254)	NC score	0.552886 (rank : 224)
Query Neighborhood Hits	430	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

DGKI_HUMAN
θ value	1.87187e-05 (rank : 255)	NC score	0.372337 (rank : 270)
Query Neighborhood Hits	430	Target Neighborhood Hits	609	Shared Neighborhood Hits	220
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

TRPC7_HUMAN
θ value	1.87187e-05 (rank : 256)	NC score	0.129873 (rank : 308)
Query Neighborhood Hits	430	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

CENG3_HUMAN
θ value	2.44474e-05 (rank : 257)	NC score	0.350353 (rank : 277)
Query Neighborhood Hits	430	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	2.44474e-05 (rank : 258)	NC score	0.350742 (rank : 276)
Query Neighborhood Hits	430	Target Neighborhood Hits	467	Shared Neighborhood Hits	231
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

TRPC7_MOUSE
θ value	2.44474e-05 (rank : 259)	NC score	0.130480 (rank : 307)
Query Neighborhood Hits	430	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

FADD_HUMAN
θ value	3.19293e-05 (rank : 260)	NC score	0.140684 (rank : 304)
Query Neighborhood Hits	430	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

ANR37_HUMAN
θ value	7.1131e-05 (rank : 261)	NC score	0.759091 (rank : 158)
Query Neighborhood Hits	430	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR43_MOUSE
θ value	7.1131e-05 (rank : 262)	NC score	0.630151 (rank : 198)
Query Neighborhood Hits	430	Target Neighborhood Hits	214	Shared Neighborhood Hits	208
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

FADD_MOUSE
θ value	7.1131e-05 (rank : 263)	NC score	0.148686 (rank : 302)
Query Neighborhood Hits	430	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

NUD12_HUMAN
θ value	7.1131e-05 (rank : 264)	NC score	0.555889 (rank : 222)
Query Neighborhood Hits	430	Target Neighborhood Hits	222	Shared Neighborhood Hits	203
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPC6_HUMAN
θ value	0.000121331 (rank : 265)	NC score	0.164469 (rank : 298)
Query Neighborhood Hits	430	Target Neighborhood Hits	171	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

AN13A_MOUSE
θ value	0.000158464 (rank : 266)	NC score	0.462994 (rank : 251)
Query Neighborhood Hits	430	Target Neighborhood Hits	226	Shared Neighborhood Hits	217
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CLR59_HUMAN
θ value	0.000158464 (rank : 267)	NC score	0.327372 (rank : 279)
Query Neighborhood Hits	430	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ANR37_MOUSE
θ value	0.000270298 (rank : 268)	NC score	0.738573 (rank : 167)
Query Neighborhood Hits	430	Target Neighborhood Hits	237	Shared Neighborhood Hits	237
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR43_HUMAN
θ value	0.000270298 (rank : 269)	NC score	0.639578 (rank : 196)
Query Neighborhood Hits	430	Target Neighborhood Hits	209	Shared Neighborhood Hits	205
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

DGKZ_HUMAN
θ value	0.000270298 (rank : 270)	NC score	0.392617 (rank : 265)
Query Neighborhood Hits	430	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

TRPV2_HUMAN
θ value	0.000270298 (rank : 271)	NC score	0.273802 (rank : 289)
Query Neighborhood Hits	430	Target Neighborhood Hits	130	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CENG2_HUMAN
θ value	0.000461057 (rank : 272)	NC score	0.375843 (rank : 268)
Query Neighborhood Hits	430	Target Neighborhood Hits	471	Shared Neighborhood Hits	254
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
θ value	0.000461057 (rank : 273)	NC score	0.372236 (rank : 271)
Query Neighborhood Hits	430	Target Neighborhood Hits	463	Shared Neighborhood Hits	250
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DDFL1_HUMAN
θ value	0.000461057 (rank : 274)	NC score	0.402957 (rank : 264)
Query Neighborhood Hits	430	Target Neighborhood Hits	353	Shared Neighborhood Hits	230
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_MOUSE
θ value	0.000461057 (rank : 275)	NC score	0.372091 (rank : 272)
Query Neighborhood Hits	430	Target Neighborhood Hits	542	Shared Neighborhood Hits	202
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

NUD12_MOUSE
θ value	0.000461057 (rank : 276)	NC score	0.585609 (rank : 215)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPC3_HUMAN
θ value	0.000461057 (rank : 277)	NC score	0.141271 (rank : 303)
Query Neighborhood Hits	430	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPV1_MOUSE
θ value	0.000461057 (rank : 278)	NC score	0.307422 (rank : 283)
Query Neighborhood Hits	430	Target Neighborhood Hits	189	Shared Neighborhood Hits	164
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ANR33_HUMAN
θ value	0.000602161 (rank : 279)	NC score	0.685391 (rank : 187)
Query Neighborhood Hits	430	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

LRRK1_HUMAN
θ value	0.000602161 (rank : 280)	NC score	0.081921 (rank : 319)
Query Neighborhood Hits	430	Target Neighborhood Hits	1237	Shared Neighborhood Hits	105
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

CDN2B_HUMAN
θ value	0.000786445 (rank : 281)	NC score	0.649700 (rank : 193)
Query Neighborhood Hits	430	Target Neighborhood Hits	196	Shared Neighborhood Hits	195
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

GLSL_HUMAN
θ value	0.000786445 (rank : 282)	NC score	0.530221 (rank : 235)
Query Neighborhood Hits	430	Target Neighborhood Hits	211	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANR33_MOUSE
θ value	0.00102713 (rank : 283)	NC score	0.695561 (rank : 181)
Query Neighborhood Hits	430	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CENG1_MOUSE
θ value	0.00102713 (rank : 284)	NC score	0.379731 (rank : 266)
Query Neighborhood Hits	430	Target Neighborhood Hits	531	Shared Neighborhood Hits	239
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

GLSL_MOUSE
θ value	0.00134147 (rank : 285)	NC score	0.516517 (rank : 238)
Query Neighborhood Hits	430	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TRPC3_MOUSE
θ value	0.00134147 (rank : 286)	NC score	0.132617 (rank : 306)
Query Neighborhood Hits	430	Target Neighborhood Hits	131	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_MOUSE
θ value	0.00134147 (rank : 287)	NC score	0.134102 (rank : 305)
Query Neighborhood Hits	430	Target Neighborhood Hits	171	Shared Neighborhood Hits	98
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

CENG1_HUMAN
θ value	0.00175202 (rank : 288)	NC score	0.377848 (rank : 267)
Query Neighborhood Hits	430	Target Neighborhood Hits	544	Shared Neighborhood Hits	241
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

TRPV1_HUMAN
θ value	0.00228821 (rank : 289)	NC score	0.289099 (rank : 287)
Query Neighborhood Hits	430	Target Neighborhood Hits	184	Shared Neighborhood Hits	156
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_MOUSE
θ value	0.00228821 (rank : 290)	NC score	0.223119 (rank : 294)
Query Neighborhood Hits	430	Target Neighborhood Hits	111	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ABTB1_HUMAN
θ value	0.00390308 (rank : 291)	NC score	0.283919 (rank : 288)
Query Neighborhood Hits	430	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	0.00390308 (rank : 292)	NC score	0.326011 (rank : 280)
Query Neighborhood Hits	430	Target Neighborhood Hits	349	Shared Neighborhood Hits	177
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

CMTA1_HUMAN
θ value	0.00390308 (rank : 293)	NC score	0.216141 (rank : 295)
Query Neighborhood Hits	430	Target Neighborhood Hits	217	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

GLSK_HUMAN
θ value	0.00390308 (rank : 294)	NC score	0.484869 (rank : 244)
Query Neighborhood Hits	430	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

RSNL2_HUMAN
θ value	0.00390308 (rank : 295)	NC score	0.267167 (rank : 291)
Query Neighborhood Hits	430	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	0.00665767 (rank : 296)	NC score	0.233183 (rank : 293)
Query Neighborhood Hits	430	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RIPK1_HUMAN
θ value	0.0113563 (rank : 297)	NC score	0.037928 (rank : 356)
Query Neighborhood Hits	430	Target Neighborhood Hits	891	Shared Neighborhood Hits	33
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SALL2_MOUSE
θ value	0.0113563 (rank : 298)	NC score	-0.006847 (rank : 458)
Query Neighborhood Hits	430	Target Neighborhood Hits	836	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

TRPV3_HUMAN
θ value	0.0113563 (rank : 299)	NC score	0.300776 (rank : 285)
Query Neighborhood Hits	430	Target Neighborhood Hits	198	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

MDN1_HUMAN
θ value	0.0148317 (rank : 300)	NC score	0.042019 (rank : 353)
Query Neighborhood Hits	430	Target Neighborhood Hits	662	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MRCKG_HUMAN
θ value	0.0148317 (rank : 301)	NC score	0.015360 (rank : 406)
Query Neighborhood Hits	430	Target Neighborhood Hits	1519	Shared Neighborhood Hits	50
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

TRPV3_MOUSE
θ value	0.0148317 (rank : 302)	NC score	0.302085 (rank : 284)
Query Neighborhood Hits	430	Target Neighborhood Hits	188	Shared Neighborhood Hits	140
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

RIPK1_MOUSE
θ value	0.0193708 (rank : 303)	NC score	0.033161 (rank : 366)
Query Neighborhood Hits	430	Target Neighborhood Hits	874	Shared Neighborhood Hits	33
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ANKR9_MOUSE
θ value	0.0252991 (rank : 304)	NC score	0.324769 (rank : 282)
Query Neighborhood Hits	430	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKZ1_MOUSE
θ value	0.0252991 (rank : 305)	NC score	0.354139 (rank : 274)
Query Neighborhood Hits	430	Target Neighborhood Hits	208	Shared Neighborhood Hits	153
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

TRPV4_HUMAN
θ value	0.0252991 (rank : 306)	NC score	0.183131 (rank : 296)
Query Neighborhood Hits	430	Target Neighborhood Hits	150	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TB182_HUMAN
θ value	0.0330416 (rank : 307)	NC score	0.031047 (rank : 372)
Query Neighborhood Hits	430	Target Neighborhood Hits	414	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

THOC1_HUMAN
θ value	0.0330416 (rank : 308)	NC score	0.059201 (rank : 329)
Query Neighborhood Hits	430	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q96FV9, Q15219	Gene names	THOC1, HPR1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

THOC1_MOUSE
θ value	0.0330416 (rank : 309)	NC score	0.060055 (rank : 327)
Query Neighborhood Hits	430	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R3N6, Q8BWD5, Q8BXY3	Gene names	Thoc1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

TRPC5_MOUSE
θ value	0.0330416 (rank : 310)	NC score	0.114476 (rank : 309)
Query Neighborhood Hits	430	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

DIAP1_HUMAN
θ value	0.0431538 (rank : 311)	NC score	0.028168 (rank : 379)
Query Neighborhood Hits	430	Target Neighborhood Hits	784	Shared Neighborhood Hits	34
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

MYH14_MOUSE
θ value	0.0431538 (rank : 312)	NC score	0.016993 (rank : 399)
Query Neighborhood Hits	430	Target Neighborhood Hits	1225	Shared Neighborhood Hits	57
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

TRPC5_HUMAN
θ value	0.0431538 (rank : 313)	NC score	0.112810 (rank : 310)
Query Neighborhood Hits	430	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

ANKZ1_HUMAN
θ value	0.0563607 (rank : 314)	NC score	0.341174 (rank : 278)
Query Neighborhood Hits	430	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

CSPG2_HUMAN
θ value	0.0563607 (rank : 315)	NC score	0.033428 (rank : 365)
Query Neighborhood Hits	430	Target Neighborhood Hits	681	Shared Neighborhood Hits	24
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

HIPK2_MOUSE
θ value	0.0563607 (rank : 316)	NC score	0.007198 (rank : 436)
Query Neighborhood Hits	430	Target Neighborhood Hits	871	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

TNR1A_HUMAN
θ value	0.0563607 (rank : 317)	NC score	0.034351 (rank : 362)
Query Neighborhood Hits	430	Target Neighborhood Hits	121	Shared Neighborhood Hits	13
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

IKBL_MOUSE
θ value	0.0736092 (rank : 318)	NC score	0.351012 (rank : 275)
Query Neighborhood Hits	430	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

TRPV4_MOUSE
θ value	0.0736092 (rank : 319)	NC score	0.171292 (rank : 297)
Query Neighborhood Hits	430	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

DIAP1_MOUSE
θ value	0.0961366 (rank : 320)	NC score	0.029643 (rank : 373)
Query Neighborhood Hits	430	Target Neighborhood Hits	839	Shared Neighborhood Hits	41
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

EP400_HUMAN
θ value	0.125558 (rank : 321)	NC score	0.013255 (rank : 415)
Query Neighborhood Hits	430	Target Neighborhood Hits	556	Shared Neighborhood Hits	19
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FMN2_MOUSE
θ value	0.125558 (rank : 322)	NC score	0.016622 (rank : 400)
Query Neighborhood Hits	430	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

HIPK1_HUMAN
θ value	0.125558 (rank : 323)	NC score	0.004098 (rank : 448)
Query Neighborhood Hits	430	Target Neighborhood Hits	843	Shared Neighborhood Hits	22
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

TR10A_HUMAN
θ value	0.125558 (rank : 324)	NC score	0.036959 (rank : 359)
Query Neighborhood Hits	430	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

UNC5C_MOUSE
θ value	0.125558 (rank : 325)	NC score	0.020075 (rank : 393)
Query Neighborhood Hits	430	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ZO1_HUMAN
θ value	0.125558 (rank : 326)	NC score	0.024491 (rank : 384)
Query Neighborhood Hits	430	Target Neighborhood Hits	474	Shared Neighborhood Hits	25
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

MY18B_HUMAN
θ value	0.163984 (rank : 327)	NC score	0.022052 (rank : 386)
Query Neighborhood Hits	430	Target Neighborhood Hits	1299	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

TREF1_HUMAN
θ value	0.163984 (rank : 328)	NC score	0.011185 (rank : 419)
Query Neighborhood Hits	430	Target Neighborhood Hits	651	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

CT012_HUMAN
θ value	0.21417 (rank : 329)	NC score	0.424583 (rank : 258)
Query Neighborhood Hits	430	Target Neighborhood Hits	205	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

IKBL_HUMAN
θ value	0.21417 (rank : 330)	NC score	0.356193 (rank : 273)
Query Neighborhood Hits	430	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

RENT2_HUMAN
θ value	0.21417 (rank : 331)	NC score	0.036547 (rank : 360)
Query Neighborhood Hits	430	Target Neighborhood Hits	618	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

ZO1_MOUSE
θ value	0.21417 (rank : 332)	NC score	0.020594 (rank : 390)
Query Neighborhood Hits	430	Target Neighborhood Hits	453	Shared Neighborhood Hits	23
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DMP1_HUMAN
θ value	0.279714 (rank : 333)	NC score	0.045708 (rank : 352)
Query Neighborhood Hits	430	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FILA_HUMAN
θ value	0.279714 (rank : 334)	NC score	0.025828 (rank : 382)
Query Neighborhood Hits	430	Target Neighborhood Hits	685	Shared Neighborhood Hits	44
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

PP2CG_HUMAN
θ value	0.279714 (rank : 335)	NC score	0.015016 (rank : 408)
Query Neighborhood Hits	430	Target Neighborhood Hits	140	Shared Neighborhood Hits	14
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

SAFB1_HUMAN
θ value	0.279714 (rank : 336)	NC score	0.006020 (rank : 442)
Query Neighborhood Hits	430	Target Neighborhood Hits	493	Shared Neighborhood Hits	17
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

TP53B_MOUSE
θ value	0.279714 (rank : 337)	NC score	0.034751 (rank : 361)
Query Neighborhood Hits	430	Target Neighborhood Hits	644	Shared Neighborhood Hits	46
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DBNL_MOUSE
θ value	0.365318 (rank : 338)	NC score	0.016079 (rank : 403)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	23
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

NFM_MOUSE
θ value	0.47712 (rank : 339)	NC score	0.021332 (rank : 387)
Query Neighborhood Hits	430	Target Neighborhood Hits	1159	Shared Neighborhood Hits	69
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

TRPC4_HUMAN
θ value	0.47712 (rank : 340)	NC score	0.110416 (rank : 312)
Query Neighborhood Hits	430	Target Neighborhood Hits	140	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0.47712 (rank : 341)	NC score	0.110534 (rank : 311)
Query Neighborhood Hits	430	Target Neighborhood Hits	141	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

UNC5C_HUMAN
θ value	0.47712 (rank : 342)	NC score	0.019353 (rank : 394)
Query Neighborhood Hits	430	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

CALX_MOUSE
θ value	0.62314 (rank : 343)	NC score	0.010443 (rank : 422)
Query Neighborhood Hits	430	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CB017_HUMAN
θ value	0.62314 (rank : 344)	NC score	0.023034 (rank : 385)
Query Neighborhood Hits	430	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

PHAR2_HUMAN
θ value	0.62314 (rank : 345)	NC score	0.033463 (rank : 364)
Query Neighborhood Hits	430	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

SYCP3_MOUSE
θ value	0.62314 (rank : 346)	NC score	0.010154 (rank : 426)
Query Neighborhood Hits	430	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

ANKF1_HUMAN
θ value	0.813845 (rank : 347)	NC score	0.155413 (rank : 300)
Query Neighborhood Hits	430	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	0.813845 (rank : 348)	NC score	0.268721 (rank : 290)
Query Neighborhood Hits	430	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CT012_MOUSE
θ value	0.813845 (rank : 349)	NC score	0.463947 (rank : 249)
Query Neighborhood Hits	430	Target Neighborhood Hits	229	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

MAGC1_HUMAN
θ value	0.813845 (rank : 350)	NC score	0.006652 (rank : 440)
Query Neighborhood Hits	430	Target Neighborhood Hits	431	Shared Neighborhood Hits	17
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MFAP1_HUMAN
θ value	0.813845 (rank : 351)	NC score	0.032560 (rank : 367)
Query Neighborhood Hits	430	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MFAP1_MOUSE
θ value	0.813845 (rank : 352)	NC score	0.032211 (rank : 369)
Query Neighborhood Hits	430	Target Neighborhood Hits	353	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

PP2CG_MOUSE
θ value	0.813845 (rank : 353)	NC score	0.014536 (rank : 410)
Query Neighborhood Hits	430	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

RB6I2_MOUSE
θ value	0.813845 (rank : 354)	NC score	0.033605 (rank : 363)
Query Neighborhood Hits	430	Target Neighborhood Hits	1433	Shared Neighborhood Hits	67
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SMBT1_HUMAN
θ value	0.813845 (rank : 355)	NC score	0.005152 (rank : 446)
Query Neighborhood Hits	430	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

TTC16_HUMAN
θ value	0.813845 (rank : 356)	NC score	0.008648 (rank : 434)
Query Neighborhood Hits	430	Target Neighborhood Hits	417	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

BAT4_MOUSE
θ value	1.06291 (rank : 357)	NC score	0.291974 (rank : 286)
Query Neighborhood Hits	430	Target Neighborhood Hits	171	Shared Neighborhood Hits	121
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

FBX39_MOUSE
θ value	1.06291 (rank : 358)	NC score	0.010397 (rank : 423)
Query Neighborhood Hits	430	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

NFM_HUMAN
θ value	1.06291 (rank : 359)	NC score	0.028349 (rank : 378)
Query Neighborhood Hits	430	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PARG_HUMAN
θ value	1.06291 (rank : 360)	NC score	0.009857 (rank : 428)
Query Neighborhood Hits	430	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

TRPC1_HUMAN
θ value	1.06291 (rank : 361)	NC score	0.088811 (rank : 317)
Query Neighborhood Hits	430	Target Neighborhood Hits	91	Shared Neighborhood Hits	60
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

WBP11_MOUSE
θ value	1.06291 (rank : 362)	NC score	0.029347 (rank : 375)
Query Neighborhood Hits	430	Target Neighborhood Hits	362	Shared Neighborhood Hits	17
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ABTAP_MOUSE
θ value	1.38821 (rank : 363)	NC score	0.027356 (rank : 380)
Query Neighborhood Hits	430	Target Neighborhood Hits	381	Shared Neighborhood Hits	31
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ACINU_HUMAN
θ value	1.38821 (rank : 364)	NC score	0.028519 (rank : 377)
Query Neighborhood Hits	430	Target Neighborhood Hits	828	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CF103_HUMAN
θ value	1.38821 (rank : 365)	NC score	0.016574 (rank : 401)
Query Neighborhood Hits	430	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

HTSF1_MOUSE
θ value	1.38821 (rank : 366)	NC score	0.017599 (rank : 397)
Query Neighborhood Hits	430	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

UNC5A_MOUSE
θ value	1.38821 (rank : 367)	NC score	0.014234 (rank : 411)
Query Neighborhood Hits	430	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

BANK1_HUMAN
θ value	1.81305 (rank : 368)	NC score	0.041898 (rank : 354)
Query Neighborhood Hits	430	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDB2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2	Gene names	BANK1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats.

FYCO1_HUMAN
θ value	1.81305 (rank : 369)	NC score	0.031580 (rank : 371)
Query Neighborhood Hits	430	Target Neighborhood Hits	1149	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TRPC1_MOUSE
θ value	1.81305 (rank : 370)	NC score	0.082677 (rank : 318)
Query Neighborhood Hits	430	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

AAT1_HUMAN
θ value	2.36792 (rank : 371)	NC score	0.012888 (rank : 416)
Query Neighborhood Hits	430	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

ACRBP_HUMAN
θ value	2.36792 (rank : 372)	NC score	0.010396 (rank : 424)
Query Neighborhood Hits	430	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEB7, Q9BY87	Gene names	ACRBP
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32) (Cancer testis antigen OY-TES-1).

ANC1_HUMAN
θ value	2.36792 (rank : 373)	NC score	0.010723 (rank : 420)
Query Neighborhood Hits	430	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

CB017_MOUSE
θ value	2.36792 (rank : 374)	NC score	0.015430 (rank : 405)
Query Neighborhood Hits	430	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

RPA1_HUMAN
θ value	2.36792 (rank : 375)	NC score	0.005276 (rank : 445)
Query Neighborhood Hits	430	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

RRP5_HUMAN
θ value	2.36792 (rank : 376)	NC score	0.013703 (rank : 413)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

TAF12_MOUSE
θ value	2.36792 (rank : 377)	NC score	0.012848 (rank : 417)
Query Neighborhood Hits	430	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VE65, Q3V0S7, Q9CZ11, Q9D8Q0	Gene names	Taf12
Domain Architecture
Description	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20).

TP53B_HUMAN
θ value	2.36792 (rank : 378)	NC score	0.020808 (rank : 389)
Query Neighborhood Hits	430	Target Neighborhood Hits	413	Shared Neighborhood Hits	29
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AP3B1_HUMAN
θ value	3.0926 (rank : 379)	NC score	0.012487 (rank : 418)
Query Neighborhood Hits	430	Target Neighborhood Hits	283	Shared Neighborhood Hits	21
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DCR1C_MOUSE
θ value	3.0926 (rank : 380)	NC score	0.008523 (rank : 435)
Query Neighborhood Hits	430	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4J0, Q8BG72, Q8BTT1	Gene names	Dclre1c, Art, Snm1l
Domain Architecture	No domain graphic available
Description	Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C protein) (mArt protein) (SNM1-like protein).

DPOLZ_MOUSE
θ value	3.0926 (rank : 381)	NC score	0.006050 (rank : 441)
Query Neighborhood Hits	430	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

NOE2_MOUSE
θ value	3.0926 (rank : 382)	NC score	0.005465 (rank : 444)
Query Neighborhood Hits	430	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

SRCH_HUMAN
θ value	3.0926 (rank : 383)	NC score	0.014142 (rank : 412)
Query Neighborhood Hits	430	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

STX7_MOUSE
θ value	3.0926 (rank : 384)	NC score	0.003720 (rank : 451)
Query Neighborhood Hits	430	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

ABCF1_HUMAN
θ value	4.03905 (rank : 385)	NC score	0.010015 (rank : 427)
Query Neighborhood Hits	430	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

BAT4_HUMAN
θ value	4.03905 (rank : 386)	NC score	0.259202 (rank : 292)
Query Neighborhood Hits	430	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

MYT1_MOUSE
θ value	4.03905 (rank : 387)	NC score	0.021011 (rank : 388)
Query Neighborhood Hits	430	Target Neighborhood Hits	385	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

SET1A_HUMAN
θ value	4.03905 (rank : 388)	NC score	0.045776 (rank : 351)
Query Neighborhood Hits	430	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

STAU1_HUMAN
θ value	4.03905 (rank : 389)	NC score	0.007048 (rank : 438)
Query Neighborhood Hits	430	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

TEX10_HUMAN
θ value	4.03905 (rank : 390)	NC score	0.008719 (rank : 433)
Query Neighborhood Hits	430	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXF1, Q5T722, Q5T723, Q8NCN8, Q8TDY0	Gene names	TEX10
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 10 protein.

UNC5A_HUMAN
θ value	4.03905 (rank : 391)	NC score	0.016039 (rank : 404)
Query Neighborhood Hits	430	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UT14A_HUMAN
θ value	4.03905 (rank : 392)	NC score	0.010495 (rank : 421)
Query Neighborhood Hits	430	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

ATRX_HUMAN
θ value	5.27518 (rank : 393)	NC score	0.018146 (rank : 396)
Query Neighborhood Hits	430	Target Neighborhood Hits	842	Shared Neighborhood Hits	53
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DDX54_MOUSE
θ value	5.27518 (rank : 394)	NC score	-0.002734 (rank : 457)
Query Neighborhood Hits	430	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

HDAC5_HUMAN
θ value	5.27518 (rank : 395)	NC score	0.008932 (rank : 432)
Query Neighborhood Hits	430	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

HDAC5_MOUSE
θ value	5.27518 (rank : 396)	NC score	0.007038 (rank : 439)
Query Neighborhood Hits	430	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

MDC1_HUMAN
θ value	5.27518 (rank : 397)	NC score	0.037834 (rank : 357)
Query Neighborhood Hits	430	Target Neighborhood Hits	1446	Shared Neighborhood Hits	77
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PCX1_HUMAN
θ value	5.27518 (rank : 398)	NC score	0.003765 (rank : 450)
Query Neighborhood Hits	430	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

RHG07_MOUSE
θ value	5.27518 (rank : 399)	NC score	-0.000689 (rank : 455)
Query Neighborhood Hits	430	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

UNC5B_MOUSE
θ value	5.27518 (rank : 400)	NC score	0.014685 (rank : 409)
Query Neighborhood Hits	430	Target Neighborhood Hits	226	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

VDP_HUMAN
θ value	5.27518 (rank : 401)	NC score	0.027117 (rank : 381)
Query Neighborhood Hits	430	Target Neighborhood Hits	645	Shared Neighborhood Hits	33
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VDP_MOUSE
θ value	5.27518 (rank : 402)	NC score	0.020456 (rank : 391)
Query Neighborhood Hits	430	Target Neighborhood Hits	469	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

AP3B2_HUMAN
θ value	6.88961 (rank : 403)	NC score	0.009548 (rank : 430)
Query Neighborhood Hits	430	Target Neighborhood Hits	246	Shared Neighborhood Hits	21
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

BANK1_MOUSE
θ value	6.88961 (rank : 404)	NC score	0.046092 (rank : 350)
Query Neighborhood Hits	430	Target Neighborhood Hits	63	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

BAZ2B_HUMAN
θ value	6.88961 (rank : 405)	NC score	0.013400 (rank : 414)
Query Neighborhood Hits	430	Target Neighborhood Hits	803	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRCA1_MOUSE
θ value	6.88961 (rank : 406)	NC score	0.018398 (rank : 395)
Query Neighborhood Hits	430	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CASC3_MOUSE
θ value	6.88961 (rank : 407)	NC score	0.009654 (rank : 429)
Query Neighborhood Hits	430	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CEP35_HUMAN
θ value	6.88961 (rank : 408)	NC score	0.037632 (rank : 358)
Query Neighborhood Hits	430	Target Neighborhood Hits	811	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

LIPS_HUMAN
θ value	6.88961 (rank : 409)	NC score	0.005778 (rank : 443)
Query Neighborhood Hits	430	Target Neighborhood Hits	314	Shared Neighborhood Hits	19
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LSD1_MOUSE
θ value	6.88961 (rank : 410)	NC score	0.015205 (rank : 407)
Query Neighborhood Hits	430	Target Neighborhood Hits	224	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PCOC1_MOUSE
θ value	6.88961 (rank : 411)	NC score	-0.000367 (rank : 454)
Query Neighborhood Hits	430	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PININ_MOUSE
θ value	6.88961 (rank : 412)	NC score	0.040302 (rank : 355)
Query Neighborhood Hits	430	Target Neighborhood Hits	777	Shared Neighborhood Hits	53
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SGT1_MOUSE
θ value	6.88961 (rank : 413)	NC score	0.004365 (rank : 447)
Query Neighborhood Hits	430	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CS74	Gene names	Ecd, Hsgt1, Sgt1
Domain Architecture
Description	SGT1 protein homolog (Ecdysoneless homolog).

TAF12_HUMAN
θ value	6.88961 (rank : 414)	NC score	0.009327 (rank : 431)
Query Neighborhood Hits	430	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q16514, Q15775	Gene names	TAF12, TAF15, TAF2J, TAFII20
Domain Architecture
Description	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15).

YTDC1_HUMAN
θ value	6.88961 (rank : 415)	NC score	0.025063 (rank : 383)
Query Neighborhood Hits	430	Target Neighborhood Hits	458	Shared Neighborhood Hits	37
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZDHC8_MOUSE
θ value	6.88961 (rank : 416)	NC score	0.020370 (rank : 392)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ABTAP_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.016344 (rank : 402)
Query Neighborhood Hits	430	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

BRCA1_HUMAN
θ value	8.99809 (rank : 418)	NC score	0.017483 (rank : 398)
Query Neighborhood Hits	430	Target Neighborhood Hits	381	Shared Neighborhood Hits	19
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BSN_MOUSE
θ value	8.99809 (rank : 419)	NC score	0.031744 (rank : 370)
Query Neighborhood Hits	430	Target Neighborhood Hits	2057	Shared Neighborhood Hits	92
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

E41L3_HUMAN
θ value	8.99809 (rank : 420)	NC score	-0.001600 (rank : 456)
Query Neighborhood Hits	430	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

M10L1_MOUSE
θ value	8.99809 (rank : 421)	NC score	0.002251 (rank : 452)
Query Neighborhood Hits	430	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

NALP1_HUMAN
θ value	8.99809 (rank : 422)	NC score	0.000053 (rank : 453)
Query Neighborhood Hits	430	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NEK1_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.010310 (rank : 425)
Query Neighborhood Hits	430	Target Neighborhood Hits	1311	Shared Neighborhood Hits	60
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

NSD1_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.029534 (rank : 374)
Query Neighborhood Hits	430	Target Neighborhood Hits	472	Shared Neighborhood Hits	23
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RP1L1_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.028732 (rank : 376)
Query Neighborhood Hits	430	Target Neighborhood Hits	1072	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SALL2_HUMAN
θ value	8.99809 (rank : 426)	NC score	-0.010124 (rank : 459)
Query Neighborhood Hits	430	Target Neighborhood Hits	835	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

SYCP1_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.032274 (rank : 368)
Query Neighborhood Hits	430	Target Neighborhood Hits	1313	Shared Neighborhood Hits	65
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

VINEX_MOUSE
θ value	8.99809 (rank : 428)	NC score	0.007139 (rank : 437)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WRN_HUMAN
θ value	8.99809 (rank : 429)	NC score	0.004061 (rank : 449)
Query Neighborhood Hits	430	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

ZSCA2_HUMAN
θ value	8.99809 (rank : 430)	NC score	-0.013667 (rank : 460)
Query Neighborhood Hits	430	Target Neighborhood Hits	803	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z7L9, Q6ZQY9, Q9NWU4	Gene names	ZSCAN2, ZFP29
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29).

ARFG1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.057567 (rank : 332)
Query Neighborhood Hits	430	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.059033 (rank : 331)
Query Neighborhood Hits	430	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.059138 (rank : 330)
Query Neighborhood Hits	430	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.059360 (rank : 328)
Query Neighborhood Hits	430	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CENA1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.061921 (rank : 324)
Query Neighborhood Hits	430	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.056319 (rank : 336)
Query Neighborhood Hits	430	Target Neighborhood Hits	83	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.057002 (rank : 334)
Query Neighborhood Hits	430	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND1_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.050655 (rank : 348)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.050945 (rank : 347)
Query Neighborhood Hits	430	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND3_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.052025 (rank : 345)
Query Neighborhood Hits	430	Target Neighborhood Hits	275	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.050337 (rank : 349)
Query Neighborhood Hits	430	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CMTA2_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.160766 (rank : 299)
Query Neighborhood Hits	430	Target Neighborhood Hits	199	Shared Neighborhood Hits	89
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.149544 (rank : 301)
Query Neighborhood Hits	430	Target Neighborhood Hits	216	Shared Neighborhood Hits	79
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CU081_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.107299 (rank : 313)
Query Neighborhood Hits	430	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

LCE1B_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.051010 (rank : 346)
Query Neighborhood Hits	430	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

RELB_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.053709 (rank : 341)
Query Neighborhood Hits	430	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.053749 (rank : 340)
Query Neighborhood Hits	430	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

REL_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.054776 (rank : 339)
Query Neighborhood Hits	430	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.055375 (rank : 338)
Query Neighborhood Hits	430	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

SMAP1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.061168 (rank : 326)
Query Neighborhood Hits	430	Target Neighborhood Hits	98	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.063386 (rank : 322)
Query Neighborhood Hits	430	Target Neighborhood Hits	120	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.062051 (rank : 323)
Query Neighborhood Hits	430	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.061611 (rank : 325)
Query Neighborhood Hits	430	Target Neighborhood Hits	70	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SPSB2_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.056741 (rank : 335)
Query Neighborhood Hits	430	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SSB4_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.057069 (rank : 333)
Query Neighborhood Hits	430	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SSB4_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.052166 (rank : 344)
Query Neighborhood Hits	430	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R5B6, Q8BJI9, Q8VHS8	Gene names	Spsb4, Ssb4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

TF65_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.052899 (rank : 343)
Query Neighborhood Hits	430	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.053663 (rank : 342)
Query Neighborhood Hits	430	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TRDN_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.055695 (rank : 337)
Query Neighborhood Hits	430	Target Neighborhood Hits	542	Shared Neighborhood Hits	28
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC2_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.067379 (rank : 321)
Query Neighborhood Hits	430	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

Hits sorted by NC score

ANK1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	430	Target Neighborhood Hits	430	Shared Neighborhood Hits	430
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK1_HUMAN
NC score	0.996190 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	430	Target Neighborhood Hits	416	Shared Neighborhood Hits	358
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
NC score	0.975361 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	430	Target Neighborhood Hits	853	Shared Neighborhood Hits	347
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR50_HUMAN
NC score	0.958273 (rank : 4)	θ value	8.20983e-86 (rank : 8)
Query Neighborhood Hits	430	Target Neighborhood Hits	361	Shared Neighborhood Hits	307
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR44_HUMAN
NC score	0.954921 (rank : 5)	θ value	6.71607e-88 (rank : 5)
Query Neighborhood Hits	430	Target Neighborhood Hits	318	Shared Neighborhood Hits	311
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.953409 (rank : 6)	θ value	9.69798e-87 (rank : 6)
Query Neighborhood Hits	430	Target Neighborhood Hits	314	Shared Neighborhood Hits	307
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
NC score	0.952537 (rank : 7)	θ value	1.65422e-86 (rank : 7)
Query Neighborhood Hits	430	Target Neighborhood Hits	314	Shared Neighborhood Hits	307
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
NC score	0.949879 (rank : 8)	θ value	1.35638e-80 (rank : 11)
Query Neighborhood Hits	430	Target Neighborhood Hits	318	Shared Neighborhood Hits	309
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.949732 (rank : 9)	θ value	6.73165e-80 (rank : 12)
Query Neighborhood Hits	430	Target Neighborhood Hits	322	Shared Neighborhood Hits	309
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNKS2_HUMAN
NC score	0.944721 (rank : 10)	θ value	2.0926e-81 (rank : 9)
Query Neighborhood Hits	430	Target Neighborhood Hits	361	Shared Neighborhood Hits	310
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
NC score	0.944253 (rank : 11)	θ value	2.73302e-81 (rank : 10)
Query Neighborhood Hits	430	Target Neighborhood Hits	477	Shared Neighborhood Hits	314
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR29_HUMAN
NC score	0.939306 (rank : 12)	θ value	2.34606e-32 (rank : 35)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	294
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR16_HUMAN
NC score	0.938737 (rank : 13)	θ value	4.42448e-31 (rank : 38)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	283
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ASB3_HUMAN
NC score	0.933487 (rank : 14)	θ value	4.568e-36 (rank : 26)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_MOUSE
NC score	0.932282 (rank : 15)	θ value	1.57e-36 (rank : 25)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	298
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

INVS_HUMAN
NC score	0.930230 (rank : 16)	θ value	7.51208e-47 (rank : 20)
Query Neighborhood Hits	430	Target Neighborhood Hits	455	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

PSD10_HUMAN
NC score	0.929071 (rank : 17)	θ value	4.73814e-25 (rank : 57)
Query Neighborhood Hits	430	Target Neighborhood Hits	301	Shared Neighborhood Hits	297
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.927881 (rank : 18)	θ value	3.62785e-25 (rank : 56)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.925913 (rank : 19)	θ value	4.42448e-31 (rank : 37)
Query Neighborhood Hits	430	Target Neighborhood Hits	439	Shared Neighborhood Hits	300
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

TRPA1_MOUSE
NC score	0.925347 (rank : 20)	θ value	4.122e-45 (rank : 21)
Query Neighborhood Hits	430	Target Neighborhood Hits	343	Shared Neighborhood Hits	302
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.924702 (rank : 21)	θ value	1.04822e-48 (rank : 17)
Query Neighborhood Hits	430	Target Neighborhood Hits	339	Shared Neighborhood Hits	306
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

INVS_MOUSE
NC score	0.922114 (rank : 22)	θ value	8.57503e-51 (rank : 15)
Query Neighborhood Hits	430	Target Neighborhood Hits	609	Shared Neighborhood Hits	303
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR42_MOUSE
NC score	0.920677 (rank : 23)	θ value	3.61944e-33 (rank : 32)
Query Neighborhood Hits	430	Target Neighborhood Hits	334	Shared Neighborhood Hits	285
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB2_HUMAN
NC score	0.920671 (rank : 24)	θ value	5.39604e-37 (rank : 24)
Query Neighborhood Hits	430	Target Neighborhood Hits	309	Shared Neighborhood Hits	295
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANK2_HUMAN
NC score	0.917591 (rank : 25)	θ value	0 (rank : 3)
Query Neighborhood Hits	430	Target Neighborhood Hits	1615	Shared Neighborhood Hits	368
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB10_MOUSE
NC score	0.915576 (rank : 26)	θ value	1.2049e-28 (rank : 42)
Query Neighborhood Hits	430	Target Neighborhood Hits	301	Shared Neighborhood Hits	287
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_HUMAN
NC score	0.915523 (rank : 27)	θ value	5.97985e-28 (rank : 46)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB2_MOUSE
NC score	0.914852 (rank : 28)	θ value	1.12514e-34 (rank : 29)
Query Neighborhood Hits	430	Target Neighborhood Hits	321	Shared Neighborhood Hits	292
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB7_MOUSE
NC score	0.914808 (rank : 29)	θ value	3.75424e-22 (rank : 70)
Query Neighborhood Hits	430	Target Neighborhood Hits	296	Shared Neighborhood Hits	288
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.914710 (rank : 30)	θ value	3.75424e-22 (rank : 69)
Query Neighborhood Hits	430	Target Neighborhood Hits	296	Shared Neighborhood Hits	288
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR42_HUMAN
NC score	0.914235 (rank : 31)	θ value	2.77775e-25 (rank : 53)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

FANK1_HUMAN
NC score	0.906627 (rank : 32)	θ value	1.5773e-20 (rank : 86)
Query Neighborhood Hits	430	Target Neighborhood Hits	326	Shared Neighborhood Hits	290
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ASB13_MOUSE
NC score	0.905274 (rank : 33)	θ value	3.62785e-25 (rank : 55)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.905261 (rank : 34)	θ value	3.62785e-25 (rank : 54)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

FANK1_MOUSE
NC score	0.903735 (rank : 35)	θ value	7.32683e-18 (rank : 109)
Query Neighborhood Hits	430	Target Neighborhood Hits	325	Shared Neighborhood Hits	285
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ASB15_HUMAN
NC score	0.900636 (rank : 36)	θ value	1.46948e-34 (rank : 30)
Query Neighborhood Hits	430	Target Neighborhood Hits	305	Shared Neighborhood Hits	287
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR23_MOUSE
NC score	0.900141 (rank : 37)	θ value	9.24701e-21 (rank : 83)
Query Neighborhood Hits	430	Target Neighborhood Hits	296	Shared Neighborhood Hits	291
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR23_HUMAN
NC score	0.899101 (rank : 38)	θ value	1.02238e-19 (rank : 88)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	288
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ASB8_MOUSE
NC score	0.898076 (rank : 39)	θ value	7.32683e-18 (rank : 108)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKS6_MOUSE
NC score	0.897453 (rank : 40)	θ value	4.00176e-32 (rank : 36)
Query Neighborhood Hits	430	Target Neighborhood Hits	435	Shared Neighborhood Hits	298
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKS6_HUMAN
NC score	0.896744 (rank : 41)	θ value	2.68423e-28 (rank : 43)
Query Neighborhood Hits	430	Target Neighborhood Hits	411	Shared Neighborhood Hits	299
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB8_HUMAN
NC score	0.896667 (rank : 42)	θ value	6.20254e-17 (rank : 119)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	288
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKR2_MOUSE
NC score	0.896404 (rank : 43)	θ value	1.33526e-19 (rank : 89)
Query Neighborhood Hits	430	Target Neighborhood Hits	312	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR2_HUMAN
NC score	0.896147 (rank : 44)	θ value	1.13037e-18 (rank : 100)
Query Neighborhood Hits	430	Target Neighborhood Hits	321	Shared Neighborhood Hits	294
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

PA2G6_MOUSE
NC score	0.896024 (rank : 45)	θ value	5.23862e-24 (rank : 61)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	291
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

BCL3_HUMAN
NC score	0.895383 (rank : 46)	θ value	3.17815e-21 (rank : 80)
Query Neighborhood Hits	430	Target Neighborhood Hits	324	Shared Neighborhood Hits	294
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANKR1_HUMAN
NC score	0.894330 (rank : 47)	θ value	1.5773e-20 (rank : 85)
Query Neighborhood Hits	430	Target Neighborhood Hits	308	Shared Neighborhood Hits	286
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
NC score	0.893420 (rank : 48)	θ value	1.47631e-18 (rank : 103)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	294
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANR39_HUMAN
NC score	0.892635 (rank : 49)	θ value	2.60593e-15 (rank : 142)
Query Neighborhood Hits	430	Target Neighborhood Hits	285	Shared Neighborhood Hits	283
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB16_MOUSE
NC score	0.891743 (rank : 50)	θ value	3.07116e-24 (rank : 59)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	285
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR49_MOUSE
NC score	0.891313 (rank : 51)	θ value	3.07829e-16 (rank : 128)
Query Neighborhood Hits	430	Target Neighborhood Hits	285	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

PA2G6_HUMAN
NC score	0.890818 (rank : 52)	θ value	5.23862e-24 (rank : 60)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	282
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

GABP2_MOUSE
NC score	0.889619 (rank : 53)	θ value	1.47631e-18 (rank : 104)
Query Neighborhood Hits	430	Target Neighborhood Hits	429	Shared Neighborhood Hits	295
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR39_MOUSE
NC score	0.889575 (rank : 54)	θ value	5.8054e-15 (rank : 148)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB15_MOUSE
NC score	0.889212 (rank : 55)	θ value	2.12192e-33 (rank : 31)
Query Neighborhood Hits	430	Target Neighborhood Hits	292	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCL3_MOUSE
NC score	0.888691 (rank : 56)	θ value	7.82807e-20 (rank : 87)
Query Neighborhood Hits	430	Target Neighborhood Hits	388	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANR49_HUMAN
NC score	0.886725 (rank : 57)	θ value	2.60593e-15 (rank : 143)
Query Neighborhood Hits	430	Target Neighborhood Hits	282	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

GABP2_HUMAN
NC score	0.886562 (rank : 58)	θ value	5.07402e-19 (rank : 96)
Query Neighborhood Hits	430	Target Neighborhood Hits	454	Shared Neighborhood Hits	297
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP3_MOUSE
NC score	0.885205 (rank : 59)	θ value	2.35696e-16 (rank : 127)
Query Neighborhood Hits	430	Target Neighborhood Hits	330	Shared Neighborhood Hits	281
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ASB14_MOUSE
NC score	0.885079 (rank : 60)	θ value	1.24688e-25 (rank : 52)
Query Neighborhood Hits	430	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB16_HUMAN
NC score	0.884600 (rank : 61)	θ value	3.28887e-18 (rank : 105)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	274
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANKS1_HUMAN
NC score	0.880481 (rank : 62)	θ value	2.51237e-26 (rank : 49)
Query Neighborhood Hits	430	Target Neighborhood Hits	438	Shared Neighborhood Hits	308
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

PP16A_MOUSE
NC score	0.879411 (rank : 63)	θ value	9.87957e-23 (rank : 67)
Query Neighborhood Hits	430	Target Neighborhood Hits	318	Shared Neighborhood Hits	286
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

MIB1_HUMAN
NC score	0.876785 (rank : 64)	θ value	1.0531e-32 (rank : 33)
Query Neighborhood Hits	430	Target Neighborhood Hits	470	Shared Neighborhood Hits	306
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.876444 (rank : 65)	θ value	1.0531e-32 (rank : 34)
Query Neighborhood Hits	430	Target Neighborhood Hits	471	Shared Neighborhood Hits	306
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANKR5_HUMAN
NC score	0.876418 (rank : 66)	θ value	2.27762e-19 (rank : 92)
Query Neighborhood Hits	430	Target Neighborhood Hits	297	Shared Neighborhood Hits	285
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_MOUSE
NC score	0.873698 (rank : 67)	θ value	9.56915e-18 (rank : 111)
Query Neighborhood Hits	430	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB5_HUMAN
NC score	0.873421 (rank : 68)	θ value	6.84181e-24 (rank : 62)
Query Neighborhood Hits	430	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB9_HUMAN
NC score	0.873263 (rank : 69)	θ value	1.42661e-21 (rank : 78)
Query Neighborhood Hits	430	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

PP16A_HUMAN
NC score	0.873231 (rank : 70)	θ value	8.36355e-22 (rank : 76)
Query Neighborhood Hits	430	Target Neighborhood Hits	340	Shared Neighborhood Hits	281
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

CT086_HUMAN
NC score	0.872609 (rank : 71)	θ value	1.58096e-12 (rank : 172)
Query Neighborhood Hits	430	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANKR5_MOUSE
NC score	0.872340 (rank : 72)	θ value	6.62687e-19 (rank : 97)
Query Neighborhood Hits	430	Target Neighborhood Hits	298	Shared Neighborhood Hits	286
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_HUMAN
NC score	0.871756 (rank : 73)	θ value	8.65492e-19 (rank : 99)
Query Neighborhood Hits	430	Target Neighborhood Hits	355	Shared Neighborhood Hits	278
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASZ1_MOUSE
NC score	0.871684 (rank : 74)	θ value	3.63628e-17 (rank : 118)
Query Neighborhood Hits	430	Target Neighborhood Hits	319	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB5_MOUSE
NC score	0.871007 (rank : 75)	θ value	8.93572e-24 (rank : 63)
Query Neighborhood Hits	430	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CDN2D_HUMAN
NC score	0.870688 (rank : 76)	θ value	1.29331e-14 (rank : 154)
Query Neighborhood Hits	430	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANKS1_MOUSE
NC score	0.869599 (rank : 77)	θ value	8.3442e-30 (rank : 39)
Query Neighborhood Hits	430	Target Neighborhood Hits	453	Shared Neighborhood Hits	303
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

CDN2C_HUMAN
NC score	0.869568 (rank : 78)	θ value	6.00763e-12 (rank : 175)
Query Neighborhood Hits	430	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ASB11_HUMAN
NC score	0.869443 (rank : 79)	θ value	4.9032e-22 (rank : 72)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MYPT1_MOUSE
NC score	0.869213 (rank : 80)	θ value	8.36355e-22 (rank : 75)
Query Neighborhood Hits	430	Target Neighborhood Hits	539	Shared Neighborhood Hits	299
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ASB11_MOUSE
NC score	0.868808 (rank : 81)	θ value	6.40375e-22 (rank : 74)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CDN2C_MOUSE
NC score	0.868609 (rank : 82)	θ value	3.89403e-11 (rank : 180)
Query Neighborhood Hits	430	Target Neighborhood Hits	270	Shared Neighborhood Hits	270
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

PP16B_HUMAN
NC score	0.868311 (rank : 83)	θ value	1.09232e-21 (rank : 77)
Query Neighborhood Hits	430	Target Neighborhood Hits	307	Shared Neighborhood Hits	283
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASZ1_HUMAN
NC score	0.867378 (rank : 84)	θ value	3.07829e-16 (rank : 130)
Query Neighborhood Hits	430	Target Neighborhood Hits	341	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MIB2_MOUSE
NC score	0.866238 (rank : 85)	θ value	1.37858e-24 (rank : 58)
Query Neighborhood Hits	430	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PP16B_MOUSE
NC score	0.866229 (rank : 86)	θ value	5.42112e-21 (rank : 82)
Query Neighborhood Hits	430	Target Neighborhood Hits	302	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANKR7_HUMAN
NC score	0.865847 (rank : 87)	θ value	1.80466e-16 (rank : 125)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	284
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

MIB2_HUMAN
NC score	0.865780 (rank : 88)	θ value	5.59698e-26 (rank : 51)
Query Neighborhood Hits	430	Target Neighborhood Hits	438	Shared Neighborhood Hits	294
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MTPN_MOUSE
NC score	0.865676 (rank : 89)	θ value	6.21693e-09 (rank : 204)
Query Neighborhood Hits	430	Target Neighborhood Hits	269	Shared Neighborhood Hits	269
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

CDN2D_MOUSE
NC score	0.865672 (rank : 90)	θ value	5.43371e-13 (rank : 167)
Query Neighborhood Hits	430	Target Neighborhood Hits	267	Shared Neighborhood Hits	266
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB4_HUMAN
NC score	0.864995 (rank : 91)	θ value	1.74391e-19 (rank : 91)
Query Neighborhood Hits	430	Target Neighborhood Hits	264	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB9_MOUSE
NC score	0.863277 (rank : 92)	θ value	1.42661e-21 (rank : 79)
Query Neighborhood Hits	430	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB4_MOUSE
NC score	0.862505 (rank : 93)	θ value	6.62687e-19 (rank : 98)
Query Neighborhood Hits	430	Target Neighborhood Hits	265	Shared Neighborhood Hits	260
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

MTPN_HUMAN
NC score	0.862318 (rank : 94)	θ value	1.38499e-08 (rank : 210)
Query Neighborhood Hits	430	Target Neighborhood Hits	269	Shared Neighborhood Hits	269
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

IKBA_HUMAN
NC score	0.861405 (rank : 95)	θ value	8.10077e-17 (rank : 121)
Query Neighborhood Hits	430	Target Neighborhood Hits	280	Shared Neighborhood Hits	278
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR10_HUMAN
NC score	0.857423 (rank : 96)	θ value	3.40345e-15 (rank : 146)
Query Neighborhood Hits	430	Target Neighborhood Hits	289	Shared Neighborhood Hits	269
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

RN5A_HUMAN
NC score	0.855867 (rank : 97)	θ value	2.97466e-19 (rank : 94)
Query Neighborhood Hits	430	Target Neighborhood Hits	608	Shared Neighborhood Hits	290
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

IKBE_MOUSE
NC score	0.855334 (rank : 98)	θ value	7.58209e-15 (rank : 151)
Query Neighborhood Hits	430	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR10_MOUSE
NC score	0.855169 (rank : 99)	θ value	4.91457e-14 (rank : 159)
Query Neighborhood Hits	430	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

MYPT2_HUMAN
NC score	0.853220 (rank : 100)	θ value	1.33526e-19 (rank : 90)
Query Neighborhood Hits	430	Target Neighborhood Hits	707	Shared Neighborhood Hits	302
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANRA2_HUMAN
NC score	0.852962 (rank : 101)	θ value	4.91457e-14 (rank : 160)
Query Neighborhood Hits	430	Target Neighborhood Hits	288	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CSKI2_MOUSE
NC score	0.852819 (rank : 102)	θ value	7.80994e-28 (rank : 47)
Query Neighborhood Hits	430	Target Neighborhood Hits	812	Shared Neighborhood Hits	302
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_HUMAN
NC score	0.852171 (rank : 103)	θ value	3.50572e-28 (rank : 45)
Query Neighborhood Hits	430	Target Neighborhood Hits	747	Shared Neighborhood Hits	307
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB12_HUMAN
NC score	0.851873 (rank : 104)	θ value	3.07829e-16 (rank : 129)
Query Neighborhood Hits	430	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

IKBA_MOUSE
NC score	0.851685 (rank : 105)	θ value	1.16975e-15 (rank : 136)
Query Neighborhood Hits	430	Target Neighborhood Hits	283	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANRA2_MOUSE
NC score	0.851634 (rank : 106)	θ value	1.86753e-13 (rank : 165)
Query Neighborhood Hits	430	Target Neighborhood Hits	287	Shared Neighborhood Hits	282
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

EHMT1_HUMAN
NC score	0.849371 (rank : 107)	θ value	2.68423e-28 (rank : 44)
Query Neighborhood Hits	430	Target Neighborhood Hits	417	Shared Neighborhood Hits	309
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

MYPT1_HUMAN
NC score	0.848753 (rank : 108)	θ value	5.42112e-21 (rank : 81)
Query Neighborhood Hits	430	Target Neighborhood Hits	723	Shared Neighborhood Hits	310
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANR22_HUMAN
NC score	0.848378 (rank : 109)	θ value	1.33837e-11 (rank : 178)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	243
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR46_HUMAN
NC score	0.848082 (rank : 110)	θ value	6.21693e-09 (rank : 202)
Query Neighborhood Hits	430	Target Neighborhood Hits	281	Shared Neighborhood Hits	277
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

RFXK_HUMAN
NC score	0.847678 (rank : 111)	θ value	3.52202e-12 (rank : 174)
Query Neighborhood Hits	430	Target Neighborhood Hits	282	Shared Neighborhood Hits	267
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ASB12_MOUSE
NC score	0.847463 (rank : 112)	θ value	3.40345e-15 (rank : 147)
Query Neighborhood Hits	430	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANFY1_MOUSE
NC score	0.846966 (rank : 113)	θ value	1.36902e-48 (rank : 18)
Query Neighborhood Hits	430	Target Neighborhood Hits	480	Shared Neighborhood Hits	305
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.845906 (rank : 114)	θ value	4.70527e-49 (rank : 16)
Query Neighborhood Hits	430	Target Neighborhood Hits	480	Shared Neighborhood Hits	297
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB1_MOUSE
NC score	0.845644 (rank : 115)	θ value	7.09661e-13 (rank : 168)
Query Neighborhood Hits	430	Target Neighborhood Hits	292	Shared Neighborhood Hits	280
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_HUMAN
NC score	0.844108 (rank : 116)	θ value	1.02475e-11 (rank : 177)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

RFXK_MOUSE
NC score	0.842726 (rank : 117)	θ value	7.09661e-13 (rank : 169)
Query Neighborhood Hits	430	Target Neighborhood Hits	273	Shared Neighborhood Hits	268
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

AN36B_HUMAN
NC score	0.842122 (rank : 118)	θ value	7.58209e-15 (rank : 150)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	291
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

CSKI1_HUMAN
NC score	0.840975 (rank : 119)	θ value	4.14116e-29 (rank : 40)
Query Neighborhood Hits	430	Target Neighborhood Hits	997	Shared Neighborhood Hits	307
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR46_MOUSE
NC score	0.840832 (rank : 120)	θ value	3.08544e-08 (rank : 213)
Query Neighborhood Hits	430	Target Neighborhood Hits	274	Shared Neighborhood Hits	270
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CSKI1_MOUSE
NC score	0.839473 (rank : 121)	θ value	7.06379e-29 (rank : 41)
Query Neighborhood Hits	430	Target Neighborhood Hits	1031	Shared Neighborhood Hits	310
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EHMT2_HUMAN
NC score	0.838987 (rank : 122)	θ value	3.28125e-26 (rank : 50)
Query Neighborhood Hits	430	Target Neighborhood Hits	498	Shared Neighborhood Hits	311
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

BARD1_HUMAN
NC score	0.835604 (rank : 123)	θ value	5.60996e-18 (rank : 107)
Query Neighborhood Hits	430	Target Neighborhood Hits	427	Shared Neighborhood Hits	295
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBB_HUMAN
NC score	0.834984 (rank : 124)	θ value	9.26847e-13 (rank : 170)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

BARD1_MOUSE
NC score	0.834848 (rank : 125)	θ value	1.24977e-17 (rank : 113)
Query Neighborhood Hits	430	Target Neighborhood Hits	411	Shared Neighborhood Hits	288
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBE_HUMAN
NC score	0.834454 (rank : 126)	θ value	1.2105e-12 (rank : 171)
Query Neighborhood Hits	430	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBB_MOUSE
NC score	0.833771 (rank : 127)	θ value	2.88119e-14 (rank : 157)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	281
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR35_HUMAN
NC score	0.832783 (rank : 128)	θ value	4.9032e-22 (rank : 71)
Query Neighborhood Hits	430	Target Neighborhood Hits	784	Shared Neighborhood Hits	307
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

EHMT2_MOUSE
NC score	0.823321 (rank : 129)	θ value	8.63488e-27 (rank : 48)
Query Neighborhood Hits	430	Target Neighborhood Hits	750	Shared Neighborhood Hits	315
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ACBD6_MOUSE
NC score	0.817125 (rank : 130)	θ value	1.17247e-07 (rank : 217)
Query Neighborhood Hits	430	Target Neighborhood Hits	305	Shared Neighborhood Hits	295
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

POTE8_HUMAN
NC score	0.815878 (rank : 131)	θ value	9.56915e-18 (rank : 112)
Query Neighborhood Hits	430	Target Neighborhood Hits	337	Shared Neighborhood Hits	294
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ACBD6_HUMAN
NC score	0.811325 (rank : 132)	θ value	5.81887e-07 (rank : 227)
Query Neighborhood Hits	430	Target Neighborhood Hits	304	Shared Neighborhood Hits	291
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR19_HUMAN
NC score	0.810729 (rank : 133)	θ value	2.60593e-15 (rank : 141)
Query Neighborhood Hits	430	Target Neighborhood Hits	276	Shared Neighborhood Hits	274
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

RN5A_MOUSE
NC score	0.806168 (rank : 134)	θ value	8.93572e-24 (rank : 64)
Query Neighborhood Hits	430	Target Neighborhood Hits	899	Shared Neighborhood Hits	308
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR32_HUMAN
NC score	0.806074 (rank : 135)	θ value	8.67504e-11 (rank : 183)
Query Neighborhood Hits	430	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR41_HUMAN
NC score	0.803261 (rank : 136)	θ value	2.52405e-10 (rank : 187)
Query Neighborhood Hits	430	Target Neighborhood Hits	332	Shared Neighborhood Hits	257
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

AN36A_HUMAN
NC score	0.799055 (rank : 137)	θ value	1.38499e-08 (rank : 209)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR32_MOUSE
NC score	0.795520 (rank : 138)	θ value	9.59137e-10 (rank : 195)
Query Neighborhood Hits	430	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

USH1G_MOUSE
NC score	0.792985 (rank : 139)	θ value	7.34386e-10 (rank : 194)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.792889 (rank : 140)	θ value	7.34386e-10 (rank : 193)
Query Neighborhood Hits	430	Target Neighborhood Hits	267	Shared Neighborhood Hits	260
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ASB6_HUMAN
NC score	0.790110 (rank : 141)	θ value	3.29651e-10 (rank : 189)
Query Neighborhood Hits	430	Target Neighborhood Hits	256	Shared Neighborhood Hits	249
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANS4B_HUMAN
NC score	0.788996 (rank : 142)	θ value	2.13673e-09 (rank : 198)
Query Neighborhood Hits	430	Target Neighborhood Hits	289	Shared Neighborhood Hits	261
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB6_MOUSE
NC score	0.785802 (rank : 143)	θ value	7.34386e-10 (rank : 192)
Query Neighborhood Hits	430	Target Neighborhood Hits	264	Shared Neighborhood Hits	247
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ZDH17_HUMAN
NC score	0.781268 (rank : 144)	θ value	6.20254e-17 (rank : 120)
Query Neighborhood Hits	430	Target Neighborhood Hits	334	Shared Neighborhood Hits	284
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

CTTB2_HUMAN
NC score	0.780427 (rank : 145)	θ value	3.39556e-23 (rank : 65)
Query Neighborhood Hits	430	Target Neighborhood Hits	1061	Shared Neighborhood Hits	313
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANS4B_MOUSE
NC score	0.779738 (rank : 146)	θ value	4.0297e-08 (rank : 215)
Query Neighborhood Hits	430	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH13_HUMAN
NC score	0.777371 (rank : 147)	θ value	1.63225e-17 (rank : 116)
Query Neighborhood Hits	430	Target Neighborhood Hits	322	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ZDH17_MOUSE
NC score	0.775930 (rank : 148)	θ value	1.38178e-16 (rank : 124)
Query Neighborhood Hits	430	Target Neighborhood Hits	328	Shared Neighborhood Hits	278
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ZDH13_MOUSE
NC score	0.773575 (rank : 149)	θ value	5.25075e-16 (rank : 133)
Query Neighborhood Hits	430	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

NFKB1_MOUSE
NC score	0.772196 (rank : 150)	θ value	3.88503e-19 (rank : 95)
Query Neighborhood Hits	430	Target Neighborhood Hits	300	Shared Neighborhood Hits	275
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR11_HUMAN
NC score	0.771960 (rank : 151)	θ value	1.058e-16 (rank : 122)
Query Neighborhood Hits	430	Target Neighborhood Hits	1289	Shared Neighborhood Hits	307
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NFKB1_HUMAN
NC score	0.769960 (rank : 152)	θ value	1.24977e-17 (rank : 114)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	282
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB2_HUMAN
NC score	0.767220 (rank : 153)	θ value	2.13179e-17 (rank : 117)
Query Neighborhood Hits	430	Target Neighborhood Hits	325	Shared Neighborhood Hits	286
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANKY2_HUMAN
NC score	0.767218 (rank : 154)	θ value	5.81887e-07 (rank : 228)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	268
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

POT15_HUMAN
NC score	0.764819 (rank : 155)	θ value	1.52774e-15 (rank : 137)
Query Neighborhood Hits	430	Target Neighborhood Hits	893	Shared Neighborhood Hits	320
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR21_HUMAN
NC score	0.763621 (rank : 156)	θ value	6.85773e-16 (rank : 134)
Query Neighborhood Hits	430	Target Neighborhood Hits	864	Shared Neighborhood Hits	319
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR15_HUMAN
NC score	0.762505 (rank : 157)	θ value	3.52202e-12 (rank : 173)
Query Neighborhood Hits	430	Target Neighborhood Hits	478	Shared Neighborhood Hits	282
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR37_HUMAN
NC score	0.759091 (rank : 158)	θ value	7.1131e-05 (rank : 261)
Query Neighborhood Hits	430	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

SNCAP_HUMAN
NC score	0.758893 (rank : 159)	θ value	1.06045e-08 (rank : 208)
Query Neighborhood Hits	430	Target Neighborhood Hits	313	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR47_MOUSE
NC score	0.753792 (rank : 160)	θ value	6.21693e-09 (rank : 203)
Query Neighborhood Hits	430	Target Neighborhood Hits	350	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFKB2_MOUSE
NC score	0.752158 (rank : 161)	θ value	3.07829e-16 (rank : 131)
Query Neighborhood Hits	430	Target Neighborhood Hits	326	Shared Neighborhood Hits	283
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR12_HUMAN
NC score	0.749306 (rank : 162)	θ value	1.38178e-16 (rank : 123)
Query Neighborhood Hits	430	Target Neighborhood Hits	1081	Shared Neighborhood Hits	314
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

POT14_HUMAN
NC score	0.746219 (rank : 163)	θ value	1.47974e-10 (rank : 185)
Query Neighborhood Hits	430	Target Neighborhood Hits	403	Shared Neighborhood Hits	287
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

SHAN1_HUMAN
NC score	0.745128 (rank : 164)	θ value	1.13037e-18 (rank : 102)
Query Neighborhood Hits	430	Target Neighborhood Hits	1041	Shared Neighborhood Hits	284
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKY2_MOUSE
NC score	0.742939 (rank : 165)	θ value	4.92598e-06 (rank : 243)
Query Neighborhood Hits	430	Target Neighborhood Hits	316	Shared Neighborhood Hits	267
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

BCOR_MOUSE
NC score	0.741379 (rank : 166)	θ value	2.52405e-10 (rank : 188)
Query Neighborhood Hits	430	Target Neighborhood Hits	521	Shared Neighborhood Hits	290
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR37_MOUSE
NC score	0.738573 (rank : 167)	θ value	0.000270298 (rank : 268)
Query Neighborhood Hits	430	Target Neighborhood Hits	237	Shared Neighborhood Hits	237
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

CD2A1_MOUSE
NC score	0.735126 (rank : 168)	θ value	9.92553e-07 (rank : 236)
Query Neighborhood Hits	430	Target Neighborhood Hits	206	Shared Neighborhood Hits	203
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

BCOR_HUMAN
NC score	0.733031 (rank : 169)	θ value	1.9326e-10 (rank : 186)
Query Neighborhood Hits	430	Target Neighborhood Hits	609	Shared Neighborhood Hits	297
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR47_HUMAN
NC score	0.732843 (rank : 170)	θ value	4.0297e-08 (rank : 214)
Query Neighborhood Hits	430	Target Neighborhood Hits	369	Shared Neighborhood Hits	259
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CLPB_MOUSE
NC score	0.718534 (rank : 171)	θ value	5.81887e-07 (rank : 230)
Query Neighborhood Hits	430	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR25_HUMAN
NC score	0.713023 (rank : 172)	θ value	1.47974e-10 (rank : 184)
Query Neighborhood Hits	430	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

CDN2B_MOUSE
NC score	0.705133 (rank : 173)	θ value	1.99992e-07 (rank : 221)
Query Neighborhood Hits	430	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

KRIT1_MOUSE
NC score	0.705116 (rank : 174)	θ value	3.41135e-07 (rank : 226)
Query Neighborhood Hits	430	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

OSBL1_HUMAN
NC score	0.698916 (rank : 175)	θ value	6.85773e-16 (rank : 135)
Query Neighborhood Hits	430	Target Neighborhood Hits	368	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

MPP8_HUMAN
NC score	0.698667 (rank : 176)	θ value	4.30538e-10 (rank : 190)
Query Neighborhood Hits	430	Target Neighborhood Hits	948	Shared Neighborhood Hits	285
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR25_MOUSE
NC score	0.698279 (rank : 177)	θ value	5.08577e-11 (rank : 181)
Query Neighborhood Hits	430	Target Neighborhood Hits	398	Shared Neighborhood Hits	264
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

A20A3_HUMAN
NC score	0.697778 (rank : 178)	θ value	2.60593e-15 (rank : 139)
Query Neighborhood Hits	430	Target Neighborhood Hits	692	Shared Neighborhood Hits	285
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.697275 (rank : 179)	θ value	3.40345e-15 (rank : 145)
Query Neighborhood Hits	430	Target Neighborhood Hits	716	Shared Neighborhood Hits	288
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.696004 (rank : 180)	θ value	3.40345e-15 (rank : 144)
Query Neighborhood Hits	430	Target Neighborhood Hits	698	Shared Neighborhood Hits	286
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR33_MOUSE
NC score	0.695561 (rank : 181)	θ value	0.00102713 (rank : 283)
Query Neighborhood Hits	430	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR38_HUMAN
NC score	0.694835 (rank : 182)	θ value	1.63604e-09 (rank : 197)
Query Neighborhood Hits	430	Target Neighborhood Hits	443	Shared Neighborhood Hits	252
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

KRIT1_HUMAN
NC score	0.694672 (rank : 183)	θ value	3.41135e-07 (rank : 225)
Query Neighborhood Hits	430	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

A20A4_HUMAN
NC score	0.693000 (rank : 184)	θ value	2.60593e-15 (rank : 140)
Query Neighborhood Hits	430	Target Neighborhood Hits	710	Shared Neighborhood Hits	286
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

POT22_HUMAN
NC score	0.691789 (rank : 185)	θ value	2.21117e-06 (rank : 239)
Query Neighborhood Hits	430	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

OSBL1_MOUSE
NC score	0.687026 (rank : 186)	θ value	1.99529e-15 (rank : 138)
Query Neighborhood Hits	430	Target Neighborhood Hits	336	Shared Neighborhood Hits	286
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR33_HUMAN
NC score	0.685391 (rank : 187)	θ value	0.000602161 (rank : 279)
Query Neighborhood Hits	430	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CD2A1_HUMAN
NC score	0.674940 (rank : 188)	θ value	7.59969e-07 (rank : 232)
Query Neighborhood Hits	430	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

RAI14_HUMAN
NC score	0.671628 (rank : 189)	θ value	4.9032e-22 (rank : 73)
Query Neighborhood Hits	430	Target Neighborhood Hits	1367	Shared Neighborhood Hits	327
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR38_MOUSE
NC score	0.670043 (rank : 190)	θ value	2.79066e-09 (rank : 199)
Query Neighborhood Hits	430	Target Neighborhood Hits	512	Shared Neighborhood Hits	240
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSTF1_MOUSE
NC score	0.664531 (rank : 191)	θ value	7.59969e-07 (rank : 235)
Query Neighborhood Hits	430	Target Neighborhood Hits	467	Shared Neighborhood Hits	259
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR45_MOUSE
NC score	0.656876 (rank : 192)	θ value	4.92598e-06 (rank : 244)
Query Neighborhood Hits	430	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CDN2B_HUMAN
NC score	0.649700 (rank : 193)	θ value	0.000786445 (rank : 281)
Query Neighborhood Hits	430	Target Neighborhood Hits	196	Shared Neighborhood Hits	195
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

OSTF1_HUMAN
NC score	0.647800 (rank : 194)	θ value	7.59969e-07 (rank : 234)
Query Neighborhood Hits	430	Target Neighborhood Hits	466	Shared Neighborhood Hits	257
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR18_HUMAN
NC score	0.646115 (rank : 195)	θ value	8.38298e-14 (rank : 162)
Query Neighborhood Hits	430	Target Neighborhood Hits	1106	Shared Neighborhood Hits	301
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR43_HUMAN
NC score	0.639578 (rank : 196)	θ value	0.000270298 (rank : 269)
Query Neighborhood Hits	430	Target Neighborhood Hits	209	Shared Neighborhood Hits	205
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

RAI14_MOUSE
NC score	0.635752 (rank : 197)	θ value	5.79196e-23 (rank : 66)
Query Neighborhood Hits	430	Target Neighborhood Hits	1505	Shared Neighborhood Hits	334
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR43_MOUSE
NC score	0.630151 (rank : 198)	θ value	7.1131e-05 (rank : 262)
Query Neighborhood Hits	430	Target Neighborhood Hits	214	Shared Neighborhood Hits	208
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CLPB_HUMAN
NC score	0.627207 (rank : 199)	θ value	2.21117e-06 (rank : 238)
Query Neighborhood Hits	430	Target Neighborhood Hits	265	Shared Neighborhood Hits	240
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

TRPV6_MOUSE
NC score	0.626228 (rank : 200)	θ value	1.42992e-13 (rank : 164)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	263
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR40_HUMAN
NC score	0.625281 (rank : 201)	θ value	2.88788e-06 (rank : 241)
Query Neighborhood Hits	430	Target Neighborhood Hits	224	Shared Neighborhood Hits	200
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANKY1_HUMAN
NC score	0.623410 (rank : 202)	θ value	1.80886e-08 (rank : 211)
Query Neighborhood Hits	430	Target Neighborhood Hits	248	Shared Neighborhood Hits	207
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

HECD1_HUMAN
NC score	0.623149 (rank : 203)	θ value	1.53129e-07 (rank : 220)
Query Neighborhood Hits	430	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR40_MOUSE
NC score	0.621546 (rank : 204)	θ value	8.40245e-06 (rank : 247)
Query Neighborhood Hits	430	Target Neighborhood Hits	228	Shared Neighborhood Hits	205
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR45_HUMAN
NC score	0.621393 (rank : 205)	θ value	5.81887e-07 (rank : 229)
Query Neighborhood Hits	430	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANKK1_HUMAN
NC score	0.609018 (rank : 206)	θ value	6.99855e-61 (rank : 13)
Query Neighborhood Hits	430	Target Neighborhood Hits	1075	Shared Neighborhood Hits	308
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

AN30A_HUMAN
NC score	0.607742 (rank : 207)	θ value	1.09485e-13 (rank : 163)
Query Neighborhood Hits	430	Target Neighborhood Hits	1119	Shared Neighborhood Hits	299
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ABTB2_HUMAN
NC score	0.606722 (rank : 208)	θ value	2.88788e-06 (rank : 240)
Query Neighborhood Hits	430	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

RIPK4_HUMAN
NC score	0.595884 (rank : 209)	θ value	1.51363e-47 (rank : 19)
Query Neighborhood Hits	430	Target Neighborhood Hits	1094	Shared Neighborhood Hits	313
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ASB14_HUMAN
NC score	0.595014 (rank : 210)	θ value	1.43324e-05 (rank : 251)
Query Neighborhood Hits	430	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANKK1_MOUSE
NC score	0.594557 (rank : 211)	θ value	2.03627e-60 (rank : 14)
Query Neighborhood Hits	430	Target Neighborhood Hits	1072	Shared Neighborhood Hits	305
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ABTB2_MOUSE
NC score	0.593679 (rank : 212)	θ value	1.09739e-05 (rank : 248)
Query Neighborhood Hits	430	Target Neighborhood Hits	414	Shared Neighborhood Hits	241
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
NC score	0.592355 (rank : 213)	θ value	5.08577e-11 (rank : 182)
Query Neighborhood Hits	430	Target Neighborhood Hits	1156	Shared Neighborhood Hits	291
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

IASPP_HUMAN
NC score	0.589231 (rank : 214)	θ value	1.17247e-07 (rank : 218)
Query Neighborhood Hits	430	Target Neighborhood Hits	688	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUD12_MOUSE
NC score	0.585609 (rank : 215)	θ value	0.000461057 (rank : 276)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CENB1_HUMAN
NC score	0.578691 (rank : 216)	θ value	6.87365e-08 (rank : 216)
Query Neighborhood Hits	430	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ASPP1_HUMAN
NC score	0.578052 (rank : 217)	θ value	3.64472e-09 (rank : 200)
Query Neighborhood Hits	430	Target Neighborhood Hits	956	Shared Neighborhood Hits	282
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENB5_HUMAN
NC score	0.576396 (rank : 218)	θ value	8.11959e-09 (rank : 206)
Query Neighborhood Hits	430	Target Neighborhood Hits	395	Shared Neighborhood Hits	261
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

TRPV5_MOUSE
NC score	0.573754 (rank : 219)	θ value	2.98157e-11 (rank : 179)
Query Neighborhood Hits	430	Target Neighborhood Hits	278	Shared Neighborhood Hits	256
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CENB2_HUMAN
NC score	0.570017 (rank : 220)	θ value	9.59137e-10 (rank : 196)
Query Neighborhood Hits	430	Target Neighborhood Hits	425	Shared Neighborhood Hits	254
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ASPP1_MOUSE
NC score	0.559389 (rank : 221)	θ value	3.64472e-09 (rank : 201)
Query Neighborhood Hits	430	Target Neighborhood Hits	1244	Shared Neighborhood Hits	289
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NUD12_HUMAN
NC score	0.555889 (rank : 222)	θ value	7.1131e-05 (rank : 264)
Query Neighborhood Hits	430	Target Neighborhood Hits	222	Shared Neighborhood Hits	203
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

GIT2_MOUSE
NC score	0.553721 (rank : 223)	θ value	8.11959e-09 (rank : 207)
Query Neighborhood Hits	430	Target Neighborhood Hits	323	Shared Neighborhood Hits	255
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

AN13B_MOUSE
NC score	0.552886 (rank : 224)	θ value	1.87187e-05 (rank : 254)
Query Neighborhood Hits	430	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.552617 (rank : 225)	θ value	1.87187e-05 (rank : 253)
Query Neighborhood Hits	430	Target Neighborhood Hits	265	Shared Neighborhood Hits	254
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13C_HUMAN
NC score	0.551269 (rank : 226)	θ value	3.77169e-06 (rank : 242)
Query Neighborhood Hits	430	Target Neighborhood Hits	241	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ILK2_HUMAN
NC score	0.546150 (rank : 227)	θ value	9.90251e-15 (rank : 153)
Query Neighborhood Hits	430	Target Neighborhood Hits	848	Shared Neighborhood Hits	289
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

TRPV6_HUMAN
NC score	0.543378 (rank : 228)	θ value	6.00763e-12 (rank : 176)
Query Neighborhood Hits	430	Target Neighborhood Hits	262	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV5_HUMAN
NC score	0.540474 (rank : 229)	θ value	4.30538e-10 (rank : 191)
Query Neighborhood Hits	430	Target Neighborhood Hits	261	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13C_MOUSE
NC score	0.538331 (rank : 230)	θ value	1.43324e-05 (rank : 250)
Query Neighborhood Hits	430	Target Neighborhood Hits	242	Shared Neighborhood Hits	234
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT1_MOUSE
NC score	0.534602 (rank : 231)	θ value	3.41135e-07 (rank : 223)
Query Neighborhood Hits	430	Target Neighborhood Hits	341	Shared Neighborhood Hits	251
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

IASPP_MOUSE
NC score	0.533409 (rank : 232)	θ value	3.41135e-07 (rank : 224)
Query Neighborhood Hits	430	Target Neighborhood Hits	1024	Shared Neighborhood Hits	272
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GIT1_HUMAN
NC score	0.533308 (rank : 233)	θ value	3.41135e-07 (rank : 222)
Query Neighborhood Hits	430	Target Neighborhood Hits	336	Shared Neighborhood Hits	251
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

UACA_HUMAN
NC score	0.531407 (rank : 234)	θ value	1.80466e-16 (rank : 126)
Query Neighborhood Hits	430	Target Neighborhood Hits	1622	Shared Neighborhood Hits	329
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GLSL_HUMAN
NC score	0.530221 (rank : 235)	θ value	0.000786445 (rank : 282)
Query Neighborhood Hits	430	Target Neighborhood Hits	211	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ILK1_HUMAN
NC score	0.527883 (rank : 236)	θ value	9.90251e-15 (rank : 152)
Query Neighborhood Hits	430	Target Neighborhood Hits	857	Shared Neighborhood Hits	289
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.525445 (rank : 237)	θ value	2.20605e-14 (rank : 156)
Query Neighborhood Hits	430	Target Neighborhood Hits	858	Shared Neighborhood Hits	289
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

GLSL_MOUSE
NC score	0.516517 (rank : 238)	θ value	0.00134147 (rank : 285)
Query Neighborhood Hits	430	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GIT2_HUMAN
NC score	0.513520 (rank : 239)	θ value	1.53129e-07 (rank : 219)
Query Neighborhood Hits	430	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

UACA_MOUSE
NC score	0.504278 (rank : 240)	θ value	3.07829e-16 (rank : 132)
Query Neighborhood Hits	430	Target Neighborhood Hits	1620	Shared Neighborhood Hits	322
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

DDFL1_MOUSE
NC score	0.498112 (rank : 241)	θ value	9.92553e-07 (rank : 237)
Query Neighborhood Hits	430	Target Neighborhood Hits	324	Shared Neighborhood Hits	251
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

AN13A_HUMAN
NC score	0.492719 (rank : 242)	θ value	1.43324e-05 (rank : 249)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	227
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

NOTC4_MOUSE
NC score	0.487845 (rank : 243)	θ value	1.29031e-22 (rank : 68)
Query Neighborhood Hits	430	Target Neighborhood Hits	872	Shared Neighborhood Hits	291
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GLSK_HUMAN
NC score	0.484869 (rank : 244)	θ value	0.00390308 (rank : 294)
Query Neighborhood Hits	430	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

ANR26_MOUSE
NC score	0.484207 (rank : 245)	θ value	6.41864e-14 (rank : 161)
Query Neighborhood Hits	430	Target Neighborhood Hits	1554	Shared Neighborhood Hits	323
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC4_HUMAN
NC score	0.481114 (rank : 246)	θ value	1.2077e-20 (rank : 84)
Query Neighborhood Hits	430	Target Neighborhood Hits	905	Shared Neighborhood Hits	294
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TNI3K_HUMAN
NC score	0.474357 (rank : 247)	θ value	8.32485e-38 (rank : 23)
Query Neighborhood Hits	430	Target Neighborhood Hits	1084	Shared Neighborhood Hits	307
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.468394 (rank : 248)	θ value	4.568e-36 (rank : 27)
Query Neighborhood Hits	430	Target Neighborhood Hits	1079	Shared Neighborhood Hits	308
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_MOUSE
NC score	0.463947 (rank : 249)	θ value	0.813845 (rank : 349)
Query Neighborhood Hits	430	Target Neighborhood Hits	229	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

ANR26_HUMAN
NC score	0.463480 (rank : 250)	θ value	3.76295e-14 (rank : 158)
Query Neighborhood Hits	430	Target Neighborhood Hits	1614	Shared Neighborhood Hits	326
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_MOUSE
NC score	0.462994 (rank : 251)	θ value	0.000158464 (rank : 266)
Query Neighborhood Hits	430	Target Neighborhood Hits	226	Shared Neighborhood Hits	217
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

NOTC3_MOUSE
NC score	0.441813 (rank : 252)	θ value	1.63225e-17 (rank : 115)
Query Neighborhood Hits	430	Target Neighborhood Hits	975	Shared Neighborhood Hits	296
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.439258 (rank : 253)	θ value	4.29542e-18 (rank : 106)
Query Neighborhood Hits	430	Target Neighborhood Hits	1062	Shared Neighborhood Hits	294
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.437629 (rank : 254)	θ value	7.32683e-18 (rank : 110)
Query Neighborhood Hits	430	Target Neighborhood Hits	906	Shared Neighborhood Hits	288
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
NC score	0.435524 (rank : 255)	θ value	2.97466e-19 (rank : 93)
Query Neighborhood Hits	430	Target Neighborhood Hits	1113	Shared Neighborhood Hits	292
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.433216 (rank : 256)	θ value	1.13037e-18 (rank : 101)
Query Neighborhood Hits	430	Target Neighborhood Hits	1069	Shared Neighborhood Hits	293
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DAPK1_MOUSE
NC score	0.425012 (rank : 257)	θ value	6.37413e-38 (rank : 22)
Query Neighborhood Hits	430	Target Neighborhood Hits	1138	Shared Neighborhood Hits	312
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

CT012_HUMAN
NC score	0.424583 (rank : 258)	θ value	0.21417 (rank : 329)
Query Neighborhood Hits	430	Target Neighborhood Hits	205	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDEF2_HUMAN
NC score	0.423255 (rank : 259)	θ value	7.59969e-07 (rank : 233)
Query Neighborhood Hits	430	Target Neighborhood Hits	599	Shared Neighborhood Hits	236
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TEX14_MOUSE
NC score	0.421358 (rank : 260)	θ value	1.80886e-08 (rank : 212)
Query Neighborhood Hits	430	Target Neighborhood Hits	1333	Shared Neighborhood Hits	286
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_HUMAN
NC score	0.420331 (rank : 261)	θ value	6.21693e-09 (rank : 205)
Query Neighborhood Hits	430	Target Neighborhood Hits	1103	Shared Neighborhood Hits	268
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDEF2_MOUSE
NC score	0.420006 (rank : 262)	θ value	5.81887e-07 (rank : 231)
Query Neighborhood Hits	430	Target Neighborhood Hits	625	Shared Neighborhood Hits	238
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DAPK1_HUMAN
NC score	0.415090 (rank : 263)	θ value	6.59618e-35 (rank : 28)
Query Neighborhood Hits	430	Target Neighborhood Hits	1130	Shared Neighborhood Hits	306
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DDFL1_HUMAN
NC score	0.402957 (rank : 264)	θ value	0.000461057 (rank : 274)
Query Neighborhood Hits	430	Target Neighborhood Hits	353	Shared Neighborhood Hits	230
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_HUMAN
NC score	0.392617 (rank : 265)	θ value	0.000270298 (rank : 270)
Query Neighborhood Hits	430	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_MOUSE
NC score	0.379731 (rank : 266)	θ value	0.00102713 (rank : 284)
Query Neighborhood Hits	430	Target Neighborhood Hits	531	Shared Neighborhood Hits	239
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.377848 (rank : 267)	θ value	0.00175202 (rank : 288)
Query Neighborhood Hits	430	Target Neighborhood Hits	544	Shared Neighborhood Hits	241
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_HUMAN
NC score	0.375843 (rank : 268)	θ value	0.000461057 (rank : 272)
Query Neighborhood Hits	430	Target Neighborhood Hits	471	Shared Neighborhood Hits	254
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

NOTC1_MOUSE
NC score	0.373411 (rank : 269)	θ value	1.68911e-14 (rank : 155)
Query Neighborhood Hits	430	Target Neighborhood Hits	916	Shared Neighborhood Hits	267
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DGKI_HUMAN
NC score	0.372337 (rank : 270)	θ value	1.87187e-05 (rank : 255)
Query Neighborhood Hits	430	Target Neighborhood Hits	609	Shared Neighborhood Hits	220
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CENG2_MOUSE
NC score	0.372236 (rank : 271)	θ value	0.000461057 (rank : 273)
Query Neighborhood Hits	430	Target Neighborhood Hits	463	Shared Neighborhood Hits	250
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DGKZ_MOUSE
NC score	0.372091 (rank : 272)	θ value	0.000461057 (rank : 275)
Query Neighborhood Hits	430	Target Neighborhood Hits	542	Shared Neighborhood Hits	202
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

IKBL_HUMAN
NC score	0.356193 (rank : 273)	θ value	0.21417 (rank : 330)
Query Neighborhood Hits	430	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANKZ1_MOUSE
NC score	0.354139 (rank : 274)	θ value	0.0252991 (rank : 305)
Query Neighborhood Hits	430	Target Neighborhood Hits	208	Shared Neighborhood Hits	153
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

IKBL_MOUSE
NC score	0.351012 (rank : 275)	θ value	0.0736092 (rank : 318)
Query Neighborhood Hits	430	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CENG3_MOUSE
NC score	0.350742 (rank : 276)	θ value	2.44474e-05 (rank : 258)
Query Neighborhood Hits	430	Target Neighborhood Hits	467	Shared Neighborhood Hits	231
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.350353 (rank : 277)	θ value	2.44474e-05 (rank : 257)
Query Neighborhood Hits	430	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ANKZ1_HUMAN
NC score	0.341174 (rank : 278)	θ value	0.0563607 (rank : 314)
Query Neighborhood Hits	430	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

CLR59_HUMAN
NC score	0.327372 (rank : 279)	θ value	0.000158464 (rank : 267)
Query Neighborhood Hits	430	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ABTB1_MOUSE
NC score	0.326011 (rank : 280)	θ value	0.00390308 (rank : 292)
Query Neighborhood Hits	430	Target Neighborhood Hits	349	Shared Neighborhood Hits	177
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

DDEF1_MOUSE
NC score	0.325986 (rank : 281)	θ value	6.43352e-06 (rank : 245)
Query Neighborhood Hits	430	Target Neighborhood Hits	592	Shared Neighborhood Hits	198
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ANKR9_MOUSE
NC score	0.324769 (rank : 282)	θ value	0.0252991 (rank : 304)
Query Neighborhood Hits	430	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TRPV1_MOUSE
NC score	0.307422 (rank : 283)	θ value	0.000461057 (rank : 278)
Query Neighborhood Hits	430	Target Neighborhood Hits	189	Shared Neighborhood Hits	164
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV3_MOUSE
NC score	0.302085 (rank : 284)	θ value	0.0148317 (rank : 302)
Query Neighborhood Hits	430	Target Neighborhood Hits	188	Shared Neighborhood Hits	140
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.300776 (rank : 285)	θ value	0.0113563 (rank : 299)
Query Neighborhood Hits	430	Target Neighborhood Hits	198	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

BAT4_MOUSE
NC score	0.291974 (rank : 286)	θ value	1.06291 (rank : 357)
Query Neighborhood Hits	430	Target Neighborhood Hits	171	Shared Neighborhood Hits	121
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

TRPV1_HUMAN
NC score	0.289099 (rank : 287)	θ value	0.00228821 (rank : 289)
Query Neighborhood Hits	430	Target Neighborhood Hits	184	Shared Neighborhood Hits	156
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

ABTB1_HUMAN
NC score	0.283919 (rank : 288)	θ value	0.00390308 (rank : 291)
Query Neighborhood Hits	430	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV2_HUMAN
NC score	0.273802 (rank : 289)	θ value	0.000270298 (rank : 271)
Query Neighborhood Hits	430	Target Neighborhood Hits	130	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ANKR9_HUMAN
NC score	0.268721 (rank : 290)	θ value	0.813845 (rank : 348)
Query Neighborhood Hits	430	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

RSNL2_HUMAN
NC score	0.267167 (rank : 291)	θ value	0.00390308 (rank : 295)
Query Neighborhood Hits	430	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

BAT4_HUMAN
NC score	0.259202 (rank : 292)	θ value	4.03905 (rank : 386)
Query Neighborhood Hits	430	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

RSNL2_MOUSE
NC score	0.233183 (rank : 293)	θ value	0.00665767 (rank : 296)
Query Neighborhood Hits	430	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV2_MOUSE
NC score	0.223119 (rank : 294)	θ value	0.00228821 (rank : 290)
Query Neighborhood Hits	430	Target Neighborhood Hits	111	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CMTA1_HUMAN
NC score	0.216141 (rank : 295)	θ value	0.00390308 (rank : 293)
Query Neighborhood Hits	430	Target Neighborhood Hits	217	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TRPV4_HUMAN
NC score	0.183131 (rank : 296)	θ value	0.0252991 (rank : 306)
Query Neighborhood Hits	430	Target Neighborhood Hits	150	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
NC score	0.171292 (rank : 297)	θ value	0.0736092 (rank : 319)
Query Neighborhood Hits	430	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC6_HUMAN
NC score	0.164469 (rank : 298)	θ value	0.000121331 (rank : 265)
Query Neighborhood Hits	430	Target Neighborhood Hits	171	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

CMTA2_HUMAN
NC score	0.160766 (rank : 299)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	430	Target Neighborhood Hits	199	Shared Neighborhood Hits	89
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ANKF1_HUMAN
NC score	0.155413 (rank : 300)	θ value	0.813845 (rank : 347)
Query Neighborhood Hits	430	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CMTA2_MOUSE
NC score	0.149544 (rank : 301)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	430	Target Neighborhood Hits	216	Shared Neighborhood Hits	79
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

FADD_MOUSE
NC score	0.148686 (rank : 302)	θ value	7.1131e-05 (rank : 263)
Query Neighborhood Hits	430	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

TRPC3_HUMAN
NC score	0.141271 (rank : 303)	θ value	0.000461057 (rank : 277)
Query Neighborhood Hits	430	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

FADD_HUMAN
NC score	0.140684 (rank : 304)	θ value	3.19293e-05 (rank : 260)
Query Neighborhood Hits	430	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

TRPC6_MOUSE
NC score	0.134102 (rank : 305)	θ value	0.00134147 (rank : 287)
Query Neighborhood Hits	430	Target Neighborhood Hits	171	Shared Neighborhood Hits	98
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC3_MOUSE
NC score	0.132617 (rank : 306)	θ value	0.00134147 (rank : 286)
Query Neighborhood Hits	430	Target Neighborhood Hits	131	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC7_MOUSE
NC score	0.130480 (rank : 307)	θ value	2.44474e-05 (rank : 259)
Query Neighborhood Hits	430	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.129873 (rank : 308)	θ value	1.87187e-05 (rank : 256)
Query Neighborhood Hits	430	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC5_MOUSE
NC score	0.114476 (rank : 309)	θ value	0.0330416 (rank : 310)
Query Neighborhood Hits	430	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.112810 (rank : 310)	θ value	0.0431538 (rank : 313)
Query Neighborhood Hits	430	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC4_MOUSE
NC score	0.110534 (rank : 311)	θ value	0.47712 (rank : 341)
Query Neighborhood Hits	430	Target Neighborhood Hits	141	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.110416 (rank : 312)	θ value	0.47712 (rank : 340)
Query Neighborhood Hits	430	Target Neighborhood Hits	140	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

CU081_HUMAN
NC score	0.107299 (rank : 313)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	430	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

LRRK1_MOUSE
NC score	0.106393 (rank : 314)	θ value	6.43352e-06 (rank : 246)
Query Neighborhood Hits	430	Target Neighborhood Hits	1267	Shared Neighborhood Hits	130
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

PIDD_HUMAN
NC score	0.095871 (rank : 315)	θ value	5.8054e-15 (rank : 149)
Query Neighborhood Hits	430	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

PIDD_MOUSE
NC score	0.092233 (rank : 316)	θ value	4.16044e-13 (rank : 166)
Query Neighborhood Hits	430	Target Neighborhood Hits	256	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

TRPC1_HUMAN
NC score	0.088811 (rank : 317)	θ value	1.06291 (rank : 361)
Query Neighborhood Hits	430	Target Neighborhood Hits	91	Shared Neighborhood Hits	60
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
NC score	0.082677 (rank : 318)	θ value	1.81305 (rank : 370)
Query Neighborhood Hits	430	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

LRRK1_HUMAN
NC score	0.081921 (rank : 319)	θ value	0.000602161 (rank : 280)
Query Neighborhood Hits	430	Target Neighborhood Hits	1237	Shared Neighborhood Hits	105
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NASP_HUMAN
NC score	0.076826 (rank : 320)	θ value	1.43324e-05 (rank : 252)
Query Neighborhood Hits	430	Target Neighborhood Hits	709	Shared Neighborhood Hits	54
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

TRPC2_MOUSE
NC score	0.067379 (rank : 321)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	430	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

SMAP1_MOUSE
NC score	0.063386 (rank : 322)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	430	Target Neighborhood Hits	120	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
NC score	0.062051 (rank : 323)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	430	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

CENA1_HUMAN
NC score	0.061921 (rank : 324)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	430	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SMP1L_MOUSE
NC score	0.061611 (rank : 325)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	430	Target Neighborhood Hits	70	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_HUMAN
NC score	0.061168 (rank : 326)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	430	Target Neighborhood Hits	98	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

THOC1_MOUSE
NC score	0.060055 (rank : 327)	θ value	0.0330416 (rank : 309)
Query Neighborhood Hits	430	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R3N6, Q8BWD5, Q8BXY3	Gene names	Thoc1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

ARFG3_MOUSE
NC score	0.059360 (rank : 328)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	430	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

THOC1_HUMAN
NC score	0.059201 (rank : 329)	θ value	0.0330416 (rank : 308)
Query Neighborhood Hits	430	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q96FV9, Q15219	Gene names	THOC1, HPR1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

ARFG3_HUMAN
NC score	0.059138 (rank : 330)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	430	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG1_MOUSE
NC score	0.059033 (rank : 331)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	430	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_HUMAN
NC score	0.057567 (rank : 332)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	430	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

SSB4_HUMAN
NC score	0.057069 (rank : 333)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	430	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

CENA2_MOUSE
NC score	0.057002 (rank : 334)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	430	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

SPSB2_MOUSE
NC score	0.056741 (rank : 335)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	430	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

CENA2_HUMAN
NC score	0.056319 (rank : 336)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	430	Target Neighborhood Hits	83	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

TRDN_HUMAN
NC score	0.055695 (rank : 337)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	430	Target Neighborhood Hits	542	Shared Neighborhood Hits	28
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

REL_MOUSE
NC score	0.055375 (rank : 338)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	430	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_HUMAN
NC score	0.054776 (rank : 339)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	430	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RELB_MOUSE
NC score	0.053749 (rank : 340)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	430	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

RELB_HUMAN
NC score	0.053709 (rank : 341)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	430	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

TF65_MOUSE
NC score	0.053663 (rank : 342)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	430	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_HUMAN
NC score	0.052899 (rank : 343)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	430	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SSB4_MOUSE
NC score	0.052166 (rank : 344)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	430	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R5B6, Q8BJI9, Q8VHS8	Gene names	Spsb4, Ssb4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

CEND3_HUMAN
NC score	0.052025 (rank : 345)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	430	Target Neighborhood Hits	275	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

LCE1B_HUMAN
NC score	0.051010 (rank : 346)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	430	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

CEND1_MOUSE
NC score	0.050945 (rank : 347)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	430	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.050655 (rank : 348)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	430	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND3_MOUSE
NC score	0.050337 (rank : 349)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	430	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

BANK1_MOUSE
NC score	0.046092 (rank : 350)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	430	Target Neighborhood Hits	63	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

SET1A_HUMAN
NC score	0.045776 (rank : 351)	θ value	4.03905 (rank : 388)
Query Neighborhood Hits	430	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

DMP1_HUMAN
NC score	0.045708 (rank : 352)	θ value	0.279714 (rank : 333)
Query Neighborhood Hits	430	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

MDN1_HUMAN
NC score	0.042019 (rank : 353)	θ value	0.0148317 (rank : 300)
Query Neighborhood Hits	430	Target Neighborhood Hits	662	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

BANK1_HUMAN
NC score	0.041898 (rank : 354)	θ value	1.81305 (rank : 368)
Query Neighborhood Hits	430	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDB2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2	Gene names	BANK1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats.

PININ_MOUSE
NC score	0.040302 (rank : 355)	θ value	6.88961 (rank : 412)
Query Neighborhood Hits	430	Target Neighborhood Hits	777	Shared Neighborhood Hits	53
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RIPK1_HUMAN
NC score	0.037928 (rank : 356)	θ value	0.0113563 (rank : 297)
Query Neighborhood Hits	430	Target Neighborhood Hits	891	Shared Neighborhood Hits	33
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

MDC1_HUMAN
NC score	0.037834 (rank : 357)	θ value	5.27518 (rank : 397)
Query Neighborhood Hits	430	Target Neighborhood Hits	1446	Shared Neighborhood Hits	77
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CEP35_HUMAN
NC score	0.037632 (rank : 358)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	430	Target Neighborhood Hits	811	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

TR10A_HUMAN
NC score	0.036959 (rank : 359)	θ value	0.125558 (rank : 324)
Query Neighborhood Hits	430	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

RENT2_HUMAN
NC score	0.036547 (rank : 360)	θ value	0.21417 (rank : 331)
Query Neighborhood Hits	430	Target Neighborhood Hits	618	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

TP53B_MOUSE
NC score	0.034751 (rank : 361)	θ value	0.279714 (rank : 337)
Query Neighborhood Hits	430	Target Neighborhood Hits	644	Shared Neighborhood Hits	46
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TNR1A_HUMAN
NC score	0.034351 (rank : 362)	θ value	0.0563607 (rank : 317)
Query Neighborhood Hits	430	Target Neighborhood Hits	121	Shared Neighborhood Hits	13
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

RB6I2_MOUSE
NC score	0.033605 (rank : 363)	θ value	0.813845 (rank : 354)
Query Neighborhood Hits	430	Target Neighborhood Hits	1433	Shared Neighborhood Hits	67
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

PHAR2_HUMAN
NC score	0.033463 (rank : 364)	θ value	0.62314 (rank : 345)
Query Neighborhood Hits	430	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

CSPG2_HUMAN
NC score	0.033428 (rank : 365)	θ value	0.0563607 (rank : 315)
Query Neighborhood Hits	430	Target Neighborhood Hits	681	Shared Neighborhood Hits	24
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

RIPK1_MOUSE
NC score	0.033161 (rank : 366)	θ value	0.0193708 (rank : 303)
Query Neighborhood Hits	430	Target Neighborhood Hits	874	Shared Neighborhood Hits	33
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

MFAP1_HUMAN
NC score	0.032560 (rank : 367)	θ value	0.813845 (rank : 351)
Query Neighborhood Hits	430	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

SYCP1_HUMAN
NC score	0.032274 (rank : 368)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	430	Target Neighborhood Hits	1313	Shared Neighborhood Hits	65
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MFAP1_MOUSE
NC score	0.032211 (rank : 369)	θ value	0.813845 (rank : 352)
Query Neighborhood Hits	430	Target Neighborhood Hits	353	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

BSN_MOUSE
NC score	0.031744 (rank : 370)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	430	Target Neighborhood Hits	2057	Shared Neighborhood Hits	92
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FYCO1_HUMAN
NC score	0.031580 (rank : 371)	θ value	1.81305 (rank : 369)
Query Neighborhood Hits	430	Target Neighborhood Hits	1149	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TB182_HUMAN
NC score	0.031047 (rank : 372)	θ value	0.0330416 (rank : 307)
Query Neighborhood Hits	430	Target Neighborhood Hits	414	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

DIAP1_MOUSE
NC score	0.029643 (rank : 373)	θ value	0.0961366 (rank : 320)
Query Neighborhood Hits	430	Target Neighborhood Hits	839	Shared Neighborhood Hits	41
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

NSD1_MOUSE
NC score	0.029534 (rank : 374)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	430	Target Neighborhood Hits	472	Shared Neighborhood Hits	23
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

WBP11_MOUSE
NC score	0.029347 (rank : 375)	θ value	1.06291 (rank : 362)
Query Neighborhood Hits	430	Target Neighborhood Hits	362	Shared Neighborhood Hits	17
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

RP1L1_HUMAN
NC score	0.028732 (rank : 376)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	430	Target Neighborhood Hits	1072	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ACINU_HUMAN
NC score	0.028519 (rank : 377)	θ value	1.38821 (rank : 364)
Query Neighborhood Hits	430	Target Neighborhood Hits	828	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NFM_HUMAN
NC score	0.028349 (rank : 378)	θ value	1.06291 (rank : 359)
Query Neighborhood Hits	430	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

DIAP1_HUMAN
NC score	0.028168 (rank : 379)	θ value	0.0431538 (rank : 311)
Query Neighborhood Hits	430	Target Neighborhood Hits	784	Shared Neighborhood Hits	34
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ABTAP_MOUSE
NC score	0.027356 (rank : 380)	θ value	1.38821 (rank : 363)
Query Neighborhood Hits	430	Target Neighborhood Hits	381	Shared Neighborhood Hits	31
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

VDP_HUMAN
NC score	0.027117 (rank : 381)	θ value	5.27518 (rank : 401)
Query Neighborhood Hits	430	Target Neighborhood Hits	645	Shared Neighborhood Hits	33
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

FILA_HUMAN
NC score	0.025828 (rank : 382)	θ value	0.279714 (rank : 334)
Query Neighborhood Hits	430	Target Neighborhood Hits	685	Shared Neighborhood Hits	44
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

YTDC1_HUMAN
NC score	0.025063 (rank : 383)	θ value	6.88961 (rank : 415)
Query Neighborhood Hits	430	Target Neighborhood Hits	458	Shared Neighborhood Hits	37
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZO1_HUMAN
NC score	0.024491 (rank : 384)	θ value	0.125558 (rank : 326)
Query Neighborhood Hits	430	Target Neighborhood Hits	474	Shared Neighborhood Hits	25
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CB017_HUMAN
NC score	0.023034 (rank : 385)	θ value	0.62314 (rank : 344)
Query Neighborhood Hits	430	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

MY18B_HUMAN
NC score	0.022052 (rank : 386)	θ value	0.163984 (rank : 327)
Query Neighborhood Hits	430	Target Neighborhood Hits	1299	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

NFM_MOUSE
NC score	0.021332 (rank : 387)	θ value	0.47712 (rank : 339)
Query Neighborhood Hits	430	Target Neighborhood Hits	1159	Shared Neighborhood Hits	69
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

MYT1_MOUSE
NC score	0.021011 (rank : 388)	θ value	4.03905 (rank : 387)
Query Neighborhood Hits	430	Target Neighborhood Hits	385	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

TP53B_HUMAN
NC score	0.020808 (rank : 389)	θ value	2.36792 (rank : 378)
Query Neighborhood Hits	430	Target Neighborhood Hits	413	Shared Neighborhood Hits	29
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZO1_MOUSE
NC score	0.020594 (rank : 390)	θ value	0.21417 (rank : 332)
Query Neighborhood Hits	430	Target Neighborhood Hits	453	Shared Neighborhood Hits	23
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

VDP_MOUSE
NC score	0.020456 (rank : 391)	θ value	5.27518 (rank : 402)
Query Neighborhood Hits	430	Target Neighborhood Hits	469	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ZDHC8_MOUSE
NC score	0.020370 (rank : 392)	θ value	6.88961 (rank : 416)
Query Neighborhood Hits	430	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

UNC5C_MOUSE
NC score	0.020075 (rank : 393)	θ value	0.125558 (rank : 325)
Query Neighborhood Hits	430	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.019353 (rank : 394)	θ value	0.47712 (rank : 342)
Query Neighborhood Hits	430	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

BRCA1_MOUSE
NC score	0.018398 (rank : 395)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	430	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

ATRX_HUMAN
NC score	0.018146 (rank : 396)	θ value	5.27518 (rank : 393)
Query Neighborhood Hits	430	Target Neighborhood Hits	842	Shared Neighborhood Hits	53
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

HTSF1_MOUSE
NC score	0.017599 (rank : 397)	θ value	1.38821 (rank : 366)
Query Neighborhood Hits	430	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

BRCA1_HUMAN
NC score	0.017483 (rank : 398)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	430	Target Neighborhood Hits	381	Shared Neighborhood Hits	19
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

MYH14_MOUSE
NC score	0.016993 (rank : 399)	θ value	0.0431538 (rank : 312)
Query Neighborhood Hits	430	Target Neighborhood Hits	1225	Shared Neighborhood Hits	57
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

FMN2_MOUSE
NC score	0.016622 (rank : 400)	θ value	0.125558 (rank : 322)
Query Neighborhood Hits	430	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

CF103_HUMAN
NC score	0.016574 (rank : 401)	θ value	1.38821 (rank : 365)
Query Neighborhood Hits	430	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

ABTAP_HUMAN
NC score	0.016344 (rank : 402)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	430	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

DBNL_MOUSE
NC score	0.016079 (rank : 403)	θ value	0.365318 (rank : 338)
Query Neighborhood Hits	430	Target Neighborhood Hits	306	Shared Neighborhood Hits	23
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

UNC5A_HUMAN
NC score	0.016039 (rank : 404)	θ value	4.03905 (rank : 391)
Query Neighborhood Hits	430	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CB017_MOUSE
NC score	0.015430 (rank : 405)	θ value	2.36792 (rank : 374)
Query Neighborhood Hits	430	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

MRCKG_HUMAN
NC score	0.015360 (rank : 406)	θ value	0.0148317 (rank : 301)
Query Neighborhood Hits	430	Target Neighborhood Hits	1519	Shared Neighborhood Hits	50
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

LSD1_MOUSE
NC score	0.015205 (rank : 407)	θ value	6.88961 (rank : 410)
Query Neighborhood Hits	430	Target Neighborhood Hits	224	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PP2CG_HUMAN
NC score	0.015016 (rank : 408)	θ value	0.279714 (rank : 335)
Query Neighborhood Hits	430	Target Neighborhood Hits	140	Shared Neighborhood Hits	14
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

UNC5B_MOUSE
NC score	0.014685 (rank : 409)	θ value	5.27518 (rank : 400)
Query Neighborhood Hits	430	Target Neighborhood Hits	226	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

PP2CG_MOUSE
NC score	0.014536 (rank : 410)	θ value	0.813845 (rank : 353)
Query Neighborhood Hits	430	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

UNC5A_MOUSE
NC score	0.014234 (rank : 411)	θ value	1.38821 (rank : 367)
Query Neighborhood Hits	430	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

SRCH_HUMAN
NC score	0.014142 (rank : 412)	θ value	3.0926 (rank : 383)
Query Neighborhood Hits	430	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

RRP5_HUMAN
NC score	0.013703 (rank : 413)	θ value	2.36792 (rank : 376)
Query Neighborhood Hits	430	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

BAZ2B_HUMAN
NC score	0.013400 (rank : 414)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	430	Target Neighborhood Hits	803	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

EP400_HUMAN
NC score	0.013255 (rank : 415)	θ value	0.125558 (rank : 321)
Query Neighborhood Hits	430	Target Neighborhood Hits	556	Shared Neighborhood Hits	19
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

AAT1_HUMAN
NC score	0.012888 (rank : 416)	θ value	2.36792 (rank : 371)
Query Neighborhood Hits	430	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

TAF12_MOUSE
NC score	0.012848 (rank : 417)	θ value	2.36792 (rank : 377)
Query Neighborhood Hits	430	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VE65, Q3V0S7, Q9CZ11, Q9D8Q0	Gene names	Taf12
Domain Architecture
Description	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20).

AP3B1_HUMAN
NC score	0.012487 (rank : 418)	θ value	3.0926 (rank : 379)
Query Neighborhood Hits	430	Target Neighborhood Hits	283	Shared Neighborhood Hits	21
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

TREF1_HUMAN
NC score	0.011185 (rank : 419)	θ value	0.163984 (rank : 328)
Query Neighborhood Hits	430	Target Neighborhood Hits	651	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

ANC1_HUMAN
NC score	0.010723 (rank : 420)	θ value	2.36792 (rank : 373)
Query Neighborhood Hits	430	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

UT14A_HUMAN
NC score	0.010495 (rank : 421)	θ value	4.03905 (rank : 392)
Query Neighborhood Hits	430	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

CALX_MOUSE
NC score	0.010443 (rank : 422)	θ value	0.62314 (rank : 343)
Query Neighborhood Hits	430	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

FBX39_MOUSE
NC score	0.010397 (rank : 423)	θ value	1.06291 (rank : 358)
Query Neighborhood Hits	430	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

ACRBP_HUMAN
NC score	0.010396 (rank : 424)	θ value	2.36792 (rank : 372)
Query Neighborhood Hits	430	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEB7, Q9BY87	Gene names	ACRBP
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32) (Cancer testis antigen OY-TES-1).

NEK1_MOUSE
NC score	0.010310 (rank : 425)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	430	Target Neighborhood Hits	1311	Shared Neighborhood Hits	60
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SYCP3_MOUSE
NC score	0.010154 (rank : 426)	θ value	0.62314 (rank : 346)
Query Neighborhood Hits	430	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

ABCF1_HUMAN
NC score	0.010015 (rank : 427)	θ value	4.03905 (rank : 385)
Query Neighborhood Hits	430	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

PARG_HUMAN
NC score	0.009857 (rank : 428)	θ value	1.06291 (rank : 360)
Query Neighborhood Hits	430	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

CASC3_MOUSE
NC score	0.009654 (rank : 429)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	430	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

AP3B2_HUMAN
NC score	0.009548 (rank : 430)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	430	Target Neighborhood Hits	246	Shared Neighborhood Hits	21
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

TAF12_HUMAN
NC score	0.009327 (rank : 431)	θ value	6.88961 (rank : 414)
Query Neighborhood Hits	430	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q16514, Q15775	Gene names	TAF12, TAF15, TAF2J, TAFII20
Domain Architecture
Description	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15).

HDAC5_HUMAN
NC score	0.008932 (rank : 432)	θ value	5.27518 (rank : 395)
Query Neighborhood Hits	430	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

TEX10_HUMAN
NC score	0.008719 (rank : 433)	θ value	4.03905 (rank : 390)
Query Neighborhood Hits	430	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXF1, Q5T722, Q5T723, Q8NCN8, Q8TDY0	Gene names	TEX10
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 10 protein.

TTC16_HUMAN
NC score	0.008648 (rank : 434)	θ value	0.813845 (rank : 356)
Query Neighborhood Hits	430	Target Neighborhood Hits	417	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

DCR1C_MOUSE
NC score	0.008523 (rank : 435)	θ value	3.0926 (rank : 380)
Query Neighborhood Hits	430	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4J0, Q8BG72, Q8BTT1	Gene names	Dclre1c, Art, Snm1l
Domain Architecture	No domain graphic available
Description	Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C protein) (mArt protein) (SNM1-like protein).

HIPK2_MOUSE
NC score	0.007198 (rank : 436)	θ value	0.0563607 (rank : 316)
Query Neighborhood Hits	430	Target Neighborhood Hits	871	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

VINEX_MOUSE
NC score	0.007139 (rank : 437)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	430	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

STAU1_HUMAN
NC score	0.007048 (rank : 438)	θ value	4.03905 (rank : 389)
Query Neighborhood Hits	430	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

HDAC5_MOUSE
NC score	0.007038 (rank : 439)	θ value	5.27518 (rank : 396)
Query Neighborhood Hits	430	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

MAGC1_HUMAN
NC score	0.006652 (rank : 440)	θ value	0.813845 (rank : 350)
Query Neighborhood Hits	430	Target Neighborhood Hits	431	Shared Neighborhood Hits	17
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

DPOLZ_MOUSE
NC score	0.006050 (rank : 441)	θ value	3.0926 (rank : 381)
Query Neighborhood Hits	430	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

SAFB1_HUMAN
NC score	0.006020 (rank : 442)	θ value	0.279714 (rank : 336)
Query Neighborhood Hits	430	Target Neighborhood Hits	493	Shared Neighborhood Hits	17
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

LIPS_HUMAN
NC score	0.005778 (rank : 443)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	430	Target Neighborhood Hits	314	Shared Neighborhood Hits	19
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

NOE2_MOUSE
NC score	0.005465 (rank : 444)	θ value	3.0926 (rank : 382)
Query Neighborhood Hits	430	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

RPA1_HUMAN
NC score	0.005276 (rank : 445)	θ value	2.36792 (rank : 375)
Query Neighborhood Hits	430	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SMBT1_HUMAN
NC score	0.005152 (rank : 446)	θ value	0.813845 (rank : 355)
Query Neighborhood Hits	430	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

SGT1_MOUSE
NC score	0.004365 (rank : 447)	θ value	6.88961 (rank : 413)
Query Neighborhood Hits	430	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CS74	Gene names	Ecd, Hsgt1, Sgt1
Domain Architecture
Description	SGT1 protein homolog (Ecdysoneless homolog).

HIPK1_HUMAN
NC score	0.004098 (rank : 448)	θ value	0.125558 (rank : 323)
Query Neighborhood Hits	430	Target Neighborhood Hits	843	Shared Neighborhood Hits	22
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

WRN_HUMAN
NC score	0.004061 (rank : 449)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	430	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

PCX1_HUMAN
NC score	0.003765 (rank : 450)	θ value	5.27518 (rank : 398)
Query Neighborhood Hits	430	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

STX7_MOUSE
NC score	0.003720 (rank : 451)	θ value	3.0926 (rank : 384)
Query Neighborhood Hits	430	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

M10L1_MOUSE
NC score	0.002251 (rank : 452)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	430	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

NALP1_HUMAN
NC score	0.000053 (rank : 453)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	430	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

PCOC1_MOUSE
NC score	-0.000367 (rank : 454)	θ value	6.88961 (rank : 411)
Query Neighborhood Hits	430	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

RHG07_MOUSE
NC score	-0.000689 (rank : 455)	θ value	5.27518 (rank : 399)
Query Neighborhood Hits	430	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

E41L3_HUMAN
NC score	-0.001600 (rank : 456)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	430	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

DDX54_MOUSE
NC score	-0.002734 (rank : 457)	θ value	5.27518 (rank : 394)
Query Neighborhood Hits	430	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

SALL2_MOUSE
NC score	-0.006847 (rank : 458)	θ value	0.0113563 (rank : 298)
Query Neighborhood Hits	430	Target Neighborhood Hits	836	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SALL2_HUMAN
NC score	-0.010124 (rank : 459)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	430	Target Neighborhood Hits	835	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

ZSCA2_HUMAN
NC score	-0.013667 (rank : 460)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	430	Target Neighborhood Hits	803	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z7L9, Q6ZQY9, Q9NWU4	Gene names	ZSCAN2, ZFP29
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29).