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Network neighborhood for query Sequence : CSKI2_HUMAN

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CSKI2_HUMAN
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CSKI1_HUMAN
θ value	0 (rank : 1)	NC score	0.947646 (rank : 3)
Query Neighborhood Hits	747	Target Neighborhood Hits	997	Shared Neighborhood Hits	529
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	0 (rank : 2)	NC score	0.942212 (rank : 4)
Query Neighborhood Hits	747	Target Neighborhood Hits	1031	Shared Neighborhood Hits	520
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	747	Target Neighborhood Hits	747	Shared Neighborhood Hits	747
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	0 (rank : 4)	NC score	0.976540 (rank : 2)
Query Neighborhood Hits	747	Target Neighborhood Hits	812	Shared Neighborhood Hits	539
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_HUMAN
θ value	7.75577e-52 (rank : 5)	NC score	0.895314 (rank : 5)
Query Neighborhood Hits	747	Target Neighborhood Hits	438	Shared Neighborhood Hits	356
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	8.02596e-49 (rank : 6)	NC score	0.890022 (rank : 6)
Query Neighborhood Hits	747	Target Neighborhood Hits	453	Shared Neighborhood Hits	360
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

RIPK4_HUMAN
θ value	5.77852e-31 (rank : 7)	NC score	0.582387 (rank : 201)
Query Neighborhood Hits	747	Target Neighborhood Hits	1094	Shared Neighborhood Hits	343
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANK1_MOUSE
θ value	3.50572e-28 (rank : 8)	NC score	0.852171 (rank : 27)
Query Neighborhood Hits	747	Target Neighborhood Hits	430	Shared Neighborhood Hits	307
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK1_HUMAN
θ value	5.97985e-28 (rank : 9)	NC score	0.852899 (rank : 26)
Query Neighborhood Hits	747	Target Neighborhood Hits	416	Shared Neighborhood Hits	306
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
θ value	1.73987e-27 (rank : 10)	NC score	0.843506 (rank : 36)
Query Neighborhood Hits	747	Target Neighborhood Hits	853	Shared Neighborhood Hits	345
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR28_MOUSE
θ value	3.28125e-26 (rank : 11)	NC score	0.855647 (rank : 22)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	296
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK2_HUMAN
θ value	4.28545e-26 (rank : 12)	NC score	0.807064 (rank : 87)
Query Neighborhood Hits	747	Target Neighborhood Hits	1615	Shared Neighborhood Hits	462
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKK1_HUMAN
θ value	1.62847e-25 (rank : 13)	NC score	0.582166 (rank : 202)
Query Neighborhood Hits	747	Target Neighborhood Hits	1075	Shared Neighborhood Hits	335
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR28_HUMAN
θ value	3.07116e-24 (rank : 14)	NC score	0.853867 (rank : 25)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKK1_MOUSE
θ value	1.16704e-23 (rank : 15)	NC score	0.568103 (rank : 208)
Query Neighborhood Hits	747	Target Neighborhood Hits	1072	Shared Neighborhood Hits	334
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR52_HUMAN
θ value	1.5242e-23 (rank : 16)	NC score	0.848754 (rank : 30)
Query Neighborhood Hits	747	Target Neighborhood Hits	322	Shared Neighborhood Hits	298
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	1.99067e-23 (rank : 17)	NC score	0.849052 (rank : 29)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNKS2_HUMAN
θ value	4.43474e-23 (rank : 18)	NC score	0.855599 (rank : 24)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR50_HUMAN
θ value	5.79196e-23 (rank : 19)	NC score	0.864769 (rank : 14)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	306
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
θ value	7.56453e-23 (rank : 20)	NC score	0.864838 (rank : 13)
Query Neighborhood Hits	747	Target Neighborhood Hits	477	Shared Neighborhood Hits	373
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR44_HUMAN
θ value	9.87957e-23 (rank : 21)	NC score	0.855626 (rank : 23)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	300
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

DAPK1_HUMAN
θ value	1.6852e-22 (rank : 22)	NC score	0.405785 (rank : 258)
Query Neighborhood Hits	747	Target Neighborhood Hits	1130	Shared Neighborhood Hits	336
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ANKR6_HUMAN
θ value	4.9032e-22 (rank : 23)	NC score	0.869086 (rank : 10)
Query Neighborhood Hits	747	Target Neighborhood Hits	439	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

DAPK1_MOUSE
θ value	6.40375e-22 (rank : 24)	NC score	0.413397 (rank : 255)
Query Neighborhood Hits	747	Target Neighborhood Hits	1138	Shared Neighborhood Hits	342
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TNI3K_HUMAN
θ value	8.36355e-22 (rank : 25)	NC score	0.471967 (rank : 239)
Query Neighborhood Hits	747	Target Neighborhood Hits	1084	Shared Neighborhood Hits	341
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

MYPT2_HUMAN
θ value	1.86321e-21 (rank : 26)	NC score	0.821399 (rank : 65)
Query Neighborhood Hits	747	Target Neighborhood Hits	707	Shared Neighborhood Hits	311
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANR42_HUMAN
θ value	3.17815e-21 (rank : 27)	NC score	0.867027 (rank : 12)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	278
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR29_HUMAN
θ value	4.15078e-21 (rank : 28)	NC score	0.877292 (rank : 7)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

MIB1_HUMAN
θ value	5.42112e-21 (rank : 29)	NC score	0.821255 (rank : 68)
Query Neighborhood Hits	747	Target Neighborhood Hits	470	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	5.42112e-21 (rank : 30)	NC score	0.820794 (rank : 69)
Query Neighborhood Hits	747	Target Neighborhood Hits	471	Shared Neighborhood Hits	300
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

TNI3K_MOUSE
θ value	7.0802e-21 (rank : 31)	NC score	0.466393 (rank : 242)
Query Neighborhood Hits	747	Target Neighborhood Hits	1079	Shared Neighborhood Hits	340
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

RAI14_HUMAN
θ value	9.24701e-21 (rank : 32)	NC score	0.635522 (rank : 186)
Query Neighborhood Hits	747	Target Neighborhood Hits	1367	Shared Neighborhood Hits	344
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR42_MOUSE
θ value	2.69047e-20 (rank : 33)	NC score	0.863198 (rank : 15)
Query Neighborhood Hits	747	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

CTTB2_HUMAN
θ value	3.51386e-20 (rank : 34)	NC score	0.746272 (rank : 140)
Query Neighborhood Hits	747	Target Neighborhood Hits	1061	Shared Neighborhood Hits	350
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ASB10_MOUSE
θ value	4.58923e-20 (rank : 35)	NC score	0.860107 (rank : 18)
Query Neighborhood Hits	747	Target Neighborhood Hits	301	Shared Neighborhood Hits	286
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

RAI14_MOUSE
θ value	2.27762e-19 (rank : 36)	NC score	0.601336 (rank : 194)
Query Neighborhood Hits	747	Target Neighborhood Hits	1505	Shared Neighborhood Hits	339
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ASB2_HUMAN
θ value	6.62687e-19 (rank : 37)	NC score	0.842379 (rank : 40)
Query Neighborhood Hits	747	Target Neighborhood Hits	309	Shared Neighborhood Hits	288
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_HUMAN
θ value	8.65492e-19 (rank : 38)	NC score	0.858444 (rank : 21)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB7_HUMAN
θ value	1.92812e-18 (rank : 39)	NC score	0.861779 (rank : 16)
Query Neighborhood Hits	747	Target Neighborhood Hits	296	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	2.5182e-18 (rank : 40)	NC score	0.861729 (rank : 17)
Query Neighborhood Hits	747	Target Neighborhood Hits	296	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

MIB2_HUMAN
θ value	3.28887e-18 (rank : 41)	NC score	0.811776 (rank : 80)
Query Neighborhood Hits	747	Target Neighborhood Hits	438	Shared Neighborhood Hits	294
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

PSD10_HUMAN
θ value	3.28887e-18 (rank : 42)	NC score	0.872627 (rank : 8)
Query Neighborhood Hits	747	Target Neighborhood Hits	301	Shared Neighborhood Hits	289
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

INVS_HUMAN
θ value	4.29542e-18 (rank : 43)	NC score	0.850711 (rank : 28)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	312
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB10_HUMAN
θ value	5.60996e-18 (rank : 44)	NC score	0.859292 (rank : 20)
Query Neighborhood Hits	747	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

INVS_MOUSE
θ value	5.60996e-18 (rank : 45)	NC score	0.847019 (rank : 33)
Query Neighborhood Hits	747	Target Neighborhood Hits	609	Shared Neighborhood Hits	346
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MYPT1_HUMAN
θ value	7.32683e-18 (rank : 46)	NC score	0.814529 (rank : 76)
Query Neighborhood Hits	747	Target Neighborhood Hits	723	Shared Neighborhood Hits	311
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ASB3_MOUSE
θ value	9.56915e-18 (rank : 47)	NC score	0.859941 (rank : 19)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

MYPT1_MOUSE
θ value	1.24977e-17 (rank : 48)	NC score	0.834106 (rank : 45)
Query Neighborhood Hits	747	Target Neighborhood Hits	539	Shared Neighborhood Hits	308
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PSD10_MOUSE
θ value	1.24977e-17 (rank : 49)	NC score	0.870954 (rank : 9)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	288
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ZDH17_HUMAN
θ value	2.13179e-17 (rank : 50)	NC score	0.752832 (rank : 134)
Query Neighborhood Hits	747	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

MIB2_MOUSE
θ value	2.7842e-17 (rank : 51)	NC score	0.812439 (rank : 79)
Query Neighborhood Hits	747	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ZDH17_MOUSE
θ value	3.63628e-17 (rank : 52)	NC score	0.748490 (rank : 137)
Query Neighborhood Hits	747	Target Neighborhood Hits	328	Shared Neighborhood Hits	277
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ASB5_HUMAN
θ value	4.74913e-17 (rank : 53)	NC score	0.817920 (rank : 73)
Query Neighborhood Hits	747	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
θ value	4.74913e-17 (rank : 54)	NC score	0.815945 (rank : 74)
Query Neighborhood Hits	747	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

PP16A_MOUSE
θ value	8.10077e-17 (rank : 55)	NC score	0.828496 (rank : 57)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	287
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANR35_HUMAN
θ value	1.80466e-16 (rank : 56)	NC score	0.774870 (rank : 122)
Query Neighborhood Hits	747	Target Neighborhood Hits	784	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

EHMT1_HUMAN
θ value	2.35696e-16 (rank : 57)	NC score	0.797949 (rank : 100)
Query Neighborhood Hits	747	Target Neighborhood Hits	417	Shared Neighborhood Hits	312
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

MUC1_HUMAN
θ value	3.07829e-16 (rank : 58)	NC score	0.124344 (rank : 317)
Query Neighborhood Hits	747	Target Neighborhood Hits	975	Shared Neighborhood Hits	173
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ASB2_MOUSE
θ value	4.02038e-16 (rank : 59)	NC score	0.837571 (rank : 43)
Query Neighborhood Hits	747	Target Neighborhood Hits	321	Shared Neighborhood Hits	289
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

TRPA1_HUMAN
θ value	4.02038e-16 (rank : 60)	NC score	0.832325 (rank : 48)
Query Neighborhood Hits	747	Target Neighborhood Hits	339	Shared Neighborhood Hits	293
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PP16B_HUMAN
θ value	6.85773e-16 (rank : 61)	NC score	0.821594 (rank : 64)
Query Neighborhood Hits	747	Target Neighborhood Hits	307	Shared Neighborhood Hits	282
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB13_MOUSE
θ value	8.95645e-16 (rank : 62)	NC score	0.846584 (rank : 34)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

NOTC4_HUMAN
θ value	8.95645e-16 (rank : 63)	NC score	0.444645 (rank : 247)
Query Neighborhood Hits	747	Target Neighborhood Hits	905	Shared Neighborhood Hits	316
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB13_HUMAN
θ value	1.52774e-15 (rank : 64)	NC score	0.846441 (rank : 35)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

TRPA1_MOUSE
θ value	1.99529e-15 (rank : 65)	NC score	0.832363 (rank : 47)
Query Neighborhood Hits	747	Target Neighborhood Hits	343	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANKR2_HUMAN
θ value	2.60593e-15 (rank : 66)	NC score	0.841085 (rank : 42)
Query Neighborhood Hits	747	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

NOTC4_MOUSE
θ value	2.60593e-15 (rank : 67)	NC score	0.449520 (rank : 245)
Query Neighborhood Hits	747	Target Neighborhood Hits	872	Shared Neighborhood Hits	306
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB9_MOUSE
θ value	3.40345e-15 (rank : 68)	NC score	0.811449 (rank : 81)
Query Neighborhood Hits	747	Target Neighborhood Hits	257	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANKR2_MOUSE
θ value	5.8054e-15 (rank : 69)	NC score	0.842960 (rank : 37)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	290
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR12_HUMAN
θ value	9.90251e-15 (rank : 70)	NC score	0.712698 (rank : 155)
Query Neighborhood Hits	747	Target Neighborhood Hits	1081	Shared Neighborhood Hits	319
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR16_HUMAN
θ value	1.29331e-14 (rank : 71)	NC score	0.867334 (rank : 11)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	282
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

PP16B_MOUSE
θ value	1.29331e-14 (rank : 72)	NC score	0.819414 (rank : 72)
Query Neighborhood Hits	747	Target Neighborhood Hits	302	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR11_HUMAN
θ value	2.20605e-14 (rank : 73)	NC score	0.751809 (rank : 135)
Query Neighborhood Hits	747	Target Neighborhood Hits	1289	Shared Neighborhood Hits	388
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PA2G6_MOUSE
θ value	2.20605e-14 (rank : 74)	NC score	0.823259 (rank : 61)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB9_HUMAN
θ value	3.76295e-14 (rank : 75)	NC score	0.820198 (rank : 71)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	257
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

EHMT2_HUMAN
θ value	4.91457e-14 (rank : 76)	NC score	0.784098 (rank : 116)
Query Neighborhood Hits	747	Target Neighborhood Hits	498	Shared Neighborhood Hits	316
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PP16A_HUMAN
θ value	4.91457e-14 (rank : 77)	NC score	0.821357 (rank : 66)
Query Neighborhood Hits	747	Target Neighborhood Hits	340	Shared Neighborhood Hits	283
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR23_MOUSE
θ value	6.41864e-14 (rank : 78)	NC score	0.841163 (rank : 41)
Query Neighborhood Hits	747	Target Neighborhood Hits	296	Shared Neighborhood Hits	289
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ZDH13_MOUSE
θ value	6.41864e-14 (rank : 79)	NC score	0.738488 (rank : 146)
Query Neighborhood Hits	747	Target Neighborhood Hits	329	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANKS6_HUMAN
θ value	8.38298e-14 (rank : 80)	NC score	0.832563 (rank : 46)
Query Neighborhood Hits	747	Target Neighborhood Hits	411	Shared Neighborhood Hits	326
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

FANK1_HUMAN
θ value	8.38298e-14 (rank : 81)	NC score	0.848654 (rank : 31)
Query Neighborhood Hits	747	Target Neighborhood Hits	326	Shared Neighborhood Hits	292
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

EHMT2_MOUSE
θ value	1.09485e-13 (rank : 82)	NC score	0.777518 (rank : 119)
Query Neighborhood Hits	747	Target Neighborhood Hits	750	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANFY1_MOUSE
θ value	2.43908e-13 (rank : 83)	NC score	0.747653 (rank : 138)
Query Neighborhood Hits	747	Target Neighborhood Hits	480	Shared Neighborhood Hits	295
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB15_HUMAN
θ value	3.18553e-13 (rank : 84)	NC score	0.814905 (rank : 75)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKS6_MOUSE
θ value	4.16044e-13 (rank : 85)	NC score	0.831910 (rank : 50)
Query Neighborhood Hits	747	Target Neighborhood Hits	435	Shared Neighborhood Hits	331
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANFY1_HUMAN
θ value	5.43371e-13 (rank : 86)	NC score	0.746187 (rank : 141)
Query Neighborhood Hits	747	Target Neighborhood Hits	480	Shared Neighborhood Hits	289
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB11_HUMAN
θ value	5.43371e-13 (rank : 87)	NC score	0.812978 (rank : 78)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

GABP2_HUMAN
θ value	7.09661e-13 (rank : 88)	NC score	0.827899 (rank : 58)
Query Neighborhood Hits	747	Target Neighborhood Hits	454	Shared Neighborhood Hits	296
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

RN5A_MOUSE
θ value	9.26847e-13 (rank : 89)	NC score	0.743854 (rank : 143)
Query Neighborhood Hits	747	Target Neighborhood Hits	899	Shared Neighborhood Hits	324
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ZDH13_HUMAN
θ value	9.26847e-13 (rank : 90)	NC score	0.736274 (rank : 148)
Query Neighborhood Hits	747	Target Neighborhood Hits	322	Shared Neighborhood Hits	276
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

GABP2_MOUSE
θ value	2.0648e-12 (rank : 91)	NC score	0.830167 (rank : 52)
Query Neighborhood Hits	747	Target Neighborhood Hits	429	Shared Neighborhood Hits	297
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB11_MOUSE
θ value	2.69671e-12 (rank : 92)	NC score	0.810112 (rank : 85)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

GABP3_MOUSE
θ value	2.69671e-12 (rank : 93)	NC score	0.828525 (rank : 56)
Query Neighborhood Hits	747	Target Neighborhood Hits	330	Shared Neighborhood Hits	278
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ILK_MOUSE
θ value	2.69671e-12 (rank : 94)	NC score	0.537455 (rank : 218)
Query Neighborhood Hits	747	Target Neighborhood Hits	858	Shared Neighborhood Hits	317
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ASB15_MOUSE
θ value	3.52202e-12 (rank : 95)	NC score	0.807047 (rank : 88)
Query Neighborhood Hits	747	Target Neighborhood Hits	292	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCL3_HUMAN
θ value	4.59992e-12 (rank : 96)	NC score	0.824887 (rank : 60)
Query Neighborhood Hits	747	Target Neighborhood Hits	324	Shared Neighborhood Hits	292
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

FANK1_MOUSE
θ value	4.59992e-12 (rank : 97)	NC score	0.847461 (rank : 32)
Query Neighborhood Hits	747	Target Neighborhood Hits	325	Shared Neighborhood Hits	291
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ILK1_HUMAN
θ value	4.59992e-12 (rank : 98)	NC score	0.538500 (rank : 217)
Query Neighborhood Hits	747	Target Neighborhood Hits	857	Shared Neighborhood Hits	317
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	4.59992e-12 (rank : 99)	NC score	0.555753 (rank : 214)
Query Neighborhood Hits	747	Target Neighborhood Hits	848	Shared Neighborhood Hits	317
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

SHAN1_HUMAN
θ value	4.59992e-12 (rank : 100)	NC score	0.745246 (rank : 142)
Query Neighborhood Hits	747	Target Neighborhood Hits	1041	Shared Neighborhood Hits	486
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR23_HUMAN
θ value	6.00763e-12 (rank : 101)	NC score	0.835743 (rank : 44)
Query Neighborhood Hits	747	Target Neighborhood Hits	291	Shared Neighborhood Hits	286
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR39_MOUSE
θ value	1.33837e-11 (rank : 102)	NC score	0.842733 (rank : 38)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB4_HUMAN
θ value	1.74796e-11 (rank : 103)	NC score	0.797860 (rank : 101)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANKR1_HUMAN
θ value	2.98157e-11 (rank : 104)	NC score	0.832017 (rank : 49)
Query Neighborhood Hits	747	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	2.98157e-11 (rank : 105)	NC score	0.831581 (rank : 51)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	289
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB4_MOUSE
θ value	2.98157e-11 (rank : 106)	NC score	0.796518 (rank : 104)
Query Neighborhood Hits	747	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

BCL3_MOUSE
θ value	2.98157e-11 (rank : 107)	NC score	0.821341 (rank : 67)
Query Neighborhood Hits	747	Target Neighborhood Hits	388	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANR39_HUMAN
θ value	3.89403e-11 (rank : 108)	NC score	0.842674 (rank : 39)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB16_MOUSE
θ value	3.89403e-11 (rank : 109)	NC score	0.820430 (rank : 70)
Query Neighborhood Hits	747	Target Neighborhood Hits	306	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

OSBL1_HUMAN
θ value	8.67504e-11 (rank : 110)	NC score	0.658821 (rank : 176)
Query Neighborhood Hits	747	Target Neighborhood Hits	368	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ASB14_MOUSE
θ value	1.133e-10 (rank : 111)	NC score	0.804070 (rank : 90)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CDN2C_HUMAN
θ value	1.133e-10 (rank : 112)	NC score	0.829593 (rank : 54)
Query Neighborhood Hits	747	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

UACA_HUMAN
θ value	1.133e-10 (rank : 113)	NC score	0.488023 (rank : 234)
Query Neighborhood Hits	747	Target Neighborhood Hits	1622	Shared Neighborhood Hits	325
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

RN5A_HUMAN
θ value	1.9326e-10 (rank : 114)	NC score	0.786499 (rank : 111)
Query Neighborhood Hits	747	Target Neighborhood Hits	608	Shared Neighborhood Hits	300
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKS3_HUMAN
θ value	2.52405e-10 (rank : 115)	NC score	0.810283 (rank : 83)
Query Neighborhood Hits	747	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

IKBE_HUMAN
θ value	2.52405e-10 (rank : 116)	NC score	0.769992 (rank : 126)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBE_MOUSE
θ value	2.52405e-10 (rank : 117)	NC score	0.787647 (rank : 109)
Query Neighborhood Hits	747	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR10_HUMAN
θ value	3.29651e-10 (rank : 118)	NC score	0.801641 (rank : 93)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR49_MOUSE
θ value	3.29651e-10 (rank : 119)	NC score	0.829815 (rank : 53)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

CDN2C_MOUSE
θ value	3.29651e-10 (rank : 120)	NC score	0.828994 (rank : 55)
Query Neighborhood Hits	747	Target Neighborhood Hits	270	Shared Neighborhood Hits	268
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKS3_MOUSE
θ value	5.62301e-10 (rank : 121)	NC score	0.813038 (rank : 77)
Query Neighborhood Hits	747	Target Neighborhood Hits	355	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR49_HUMAN
θ value	5.62301e-10 (rank : 122)	NC score	0.825463 (rank : 59)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

BARD1_HUMAN
θ value	5.62301e-10 (rank : 123)	NC score	0.785847 (rank : 113)
Query Neighborhood Hits	747	Target Neighborhood Hits	427	Shared Neighborhood Hits	291
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBA_HUMAN
θ value	5.62301e-10 (rank : 124)	NC score	0.799342 (rank : 97)
Query Neighborhood Hits	747	Target Neighborhood Hits	280	Shared Neighborhood Hits	272
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

KRIT1_MOUSE
θ value	5.62301e-10 (rank : 125)	NC score	0.699562 (rank : 162)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	228
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

BARD1_MOUSE
θ value	7.34386e-10 (rank : 126)	NC score	0.784527 (rank : 115)
Query Neighborhood Hits	747	Target Neighborhood Hits	411	Shared Neighborhood Hits	286
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

AN30A_HUMAN
θ value	9.59137e-10 (rank : 127)	NC score	0.563985 (rank : 210)
Query Neighborhood Hits	747	Target Neighborhood Hits	1119	Shared Neighborhood Hits	312
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

IKBA_MOUSE
θ value	9.59137e-10 (rank : 128)	NC score	0.788148 (rank : 108)
Query Neighborhood Hits	747	Target Neighborhood Hits	283	Shared Neighborhood Hits	273
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

MPP8_HUMAN
θ value	9.59137e-10 (rank : 129)	NC score	0.655053 (rank : 178)
Query Neighborhood Hits	747	Target Neighborhood Hits	948	Shared Neighborhood Hits	289
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR19_HUMAN
θ value	1.63604e-09 (rank : 130)	NC score	0.741355 (rank : 144)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	271
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

UACA_MOUSE
θ value	1.63604e-09 (rank : 131)	NC score	0.462982 (rank : 244)
Query Neighborhood Hits	747	Target Neighborhood Hits	1620	Shared Neighborhood Hits	327
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANR32_HUMAN
θ value	2.13673e-09 (rank : 132)	NC score	0.771532 (rank : 125)
Query Neighborhood Hits	747	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

MAGE1_HUMAN
θ value	2.13673e-09 (rank : 133)	NC score	0.099122 (rank : 394)
Query Neighborhood Hits	747	Target Neighborhood Hits	1389	Shared Neighborhood Hits	231
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ANR18_HUMAN
θ value	2.79066e-09 (rank : 134)	NC score	0.593655 (rank : 197)
Query Neighborhood Hits	747	Target Neighborhood Hits	1106	Shared Neighborhood Hits	305
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASZ1_HUMAN
θ value	2.79066e-09 (rank : 135)	NC score	0.803468 (rank : 91)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKR7_HUMAN
θ value	3.64472e-09 (rank : 136)	NC score	0.790122 (rank : 107)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	276
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANKR5_MOUSE
θ value	4.76016e-09 (rank : 137)	NC score	0.808046 (rank : 86)
Query Neighborhood Hits	747	Target Neighborhood Hits	298	Shared Neighborhood Hits	286
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB8_HUMAN
θ value	4.76016e-09 (rank : 138)	NC score	0.822394 (rank : 63)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	4.76016e-09 (rank : 139)	NC score	0.823010 (rank : 62)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

OSBL1_MOUSE
θ value	6.21693e-09 (rank : 140)	NC score	0.646974 (rank : 182)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	284
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

USH1G_HUMAN
θ value	6.21693e-09 (rank : 141)	NC score	0.760914 (rank : 130)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	6.21693e-09 (rank : 142)	NC score	0.760704 (rank : 131)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

POT15_HUMAN
θ value	8.11959e-09 (rank : 143)	NC score	0.700501 (rank : 160)
Query Neighborhood Hits	747	Target Neighborhood Hits	893	Shared Neighborhood Hits	313
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

AN36B_HUMAN
θ value	1.06045e-08 (rank : 144)	NC score	0.773419 (rank : 124)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	283
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ASB12_MOUSE
θ value	1.06045e-08 (rank : 145)	NC score	0.787146 (rank : 110)
Query Neighborhood Hits	747	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANKR5_HUMAN
θ value	1.38499e-08 (rank : 146)	NC score	0.804657 (rank : 89)
Query Neighborhood Hits	747	Target Neighborhood Hits	297	Shared Neighborhood Hits	284
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANRA2_HUMAN
θ value	1.38499e-08 (rank : 147)	NC score	0.796984 (rank : 103)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	278
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR21_HUMAN
θ value	1.80886e-08 (rank : 148)	NC score	0.701328 (rank : 159)
Query Neighborhood Hits	747	Target Neighborhood Hits	864	Shared Neighborhood Hits	310
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR22_HUMAN
θ value	1.80886e-08 (rank : 149)	NC score	0.790239 (rank : 106)
Query Neighborhood Hits	747	Target Neighborhood Hits	243	Shared Neighborhood Hits	241
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR10_MOUSE
θ value	3.08544e-08 (rank : 150)	NC score	0.801082 (rank : 95)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASZ1_MOUSE
θ value	3.08544e-08 (rank : 151)	NC score	0.798599 (rank : 98)
Query Neighborhood Hits	747	Target Neighborhood Hits	319	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

KRIT1_HUMAN
θ value	3.08544e-08 (rank : 152)	NC score	0.689862 (rank : 166)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	220
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

POTE8_HUMAN
θ value	3.08544e-08 (rank : 153)	NC score	0.746410 (rank : 139)
Query Neighborhood Hits	747	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANR15_HUMAN
θ value	4.0297e-08 (rank : 154)	NC score	0.715593 (rank : 154)
Query Neighborhood Hits	747	Target Neighborhood Hits	478	Shared Neighborhood Hits	277
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANRA2_MOUSE
θ value	4.0297e-08 (rank : 155)	NC score	0.793428 (rank : 105)
Query Neighborhood Hits	747	Target Neighborhood Hits	287	Shared Neighborhood Hits	277
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

NOTC2_MOUSE
θ value	4.0297e-08 (rank : 156)	NC score	0.391630 (rank : 263)
Query Neighborhood Hits	747	Target Neighborhood Hits	1069	Shared Neighborhood Hits	325
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANR32_MOUSE
θ value	6.87365e-08 (rank : 157)	NC score	0.759213 (rank : 132)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

NFKB1_HUMAN
θ value	6.87365e-08 (rank : 158)	NC score	0.699985 (rank : 161)
Query Neighborhood Hits	747	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ASB16_HUMAN
θ value	8.97725e-08 (rank : 159)	NC score	0.810224 (rank : 84)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NFKB1_MOUSE
θ value	8.97725e-08 (rank : 160)	NC score	0.699422 (rank : 163)
Query Neighborhood Hits	747	Target Neighborhood Hits	300	Shared Neighborhood Hits	273
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NOTC2_HUMAN
θ value	8.97725e-08 (rank : 161)	NC score	0.395459 (rank : 261)
Query Neighborhood Hits	747	Target Neighborhood Hits	1113	Shared Neighborhood Hits	348
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CDN2D_HUMAN
θ value	1.99992e-07 (rank : 162)	NC score	0.810973 (rank : 82)
Query Neighborhood Hits	747	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2D_MOUSE
θ value	1.99992e-07 (rank : 163)	NC score	0.802480 (rank : 92)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	265
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

NOTC3_MOUSE
θ value	1.99992e-07 (rank : 164)	NC score	0.402836 (rank : 259)
Query Neighborhood Hits	747	Target Neighborhood Hits	975	Shared Neighborhood Hits	343
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANR47_MOUSE
θ value	2.61198e-07 (rank : 165)	NC score	0.711753 (rank : 156)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	268
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANS4B_HUMAN
θ value	2.61198e-07 (rank : 166)	NC score	0.751424 (rank : 136)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

NOTC3_HUMAN
θ value	2.61198e-07 (rank : 167)	NC score	0.401032 (rank : 260)
Query Neighborhood Hits	747	Target Neighborhood Hits	1062	Shared Neighborhood Hits	349
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ACBD6_MOUSE
θ value	3.41135e-07 (rank : 168)	NC score	0.773546 (rank : 123)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	288
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

BCOR_HUMAN
θ value	3.41135e-07 (rank : 169)	NC score	0.697604 (rank : 164)
Query Neighborhood Hits	747	Target Neighborhood Hits	609	Shared Neighborhood Hits	321
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	3.41135e-07 (rank : 170)	NC score	0.705316 (rank : 158)
Query Neighborhood Hits	747	Target Neighborhood Hits	521	Shared Neighborhood Hits	310
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ACBD6_HUMAN
θ value	4.45536e-07 (rank : 171)	NC score	0.767093 (rank : 127)
Query Neighborhood Hits	747	Target Neighborhood Hits	304	Shared Neighborhood Hits	286
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IKBB_MOUSE
θ value	4.45536e-07 (rank : 172)	NC score	0.762093 (rank : 129)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

NOTC1_HUMAN
θ value	4.45536e-07 (rank : 173)	NC score	0.394362 (rank : 262)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	307
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PA2G6_HUMAN
θ value	4.45536e-07 (rank : 174)	NC score	0.800963 (rank : 96)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ABTB2_HUMAN
θ value	5.81887e-07 (rank : 175)	NC score	0.578419 (rank : 204)
Query Neighborhood Hits	747	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR26_MOUSE
θ value	7.59969e-07 (rank : 176)	NC score	0.439595 (rank : 250)
Query Neighborhood Hits	747	Target Neighborhood Hits	1554	Shared Neighborhood Hits	331
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

OSTF1_HUMAN
θ value	7.59969e-07 (rank : 177)	NC score	0.644242 (rank : 183)
Query Neighborhood Hits	747	Target Neighborhood Hits	466	Shared Neighborhood Hits	296
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ASB1_MOUSE
θ value	9.92553e-07 (rank : 178)	NC score	0.776683 (rank : 120)
Query Neighborhood Hits	747	Target Neighborhood Hits	292	Shared Neighborhood Hits	275
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENB5_HUMAN
θ value	9.92553e-07 (rank : 179)	NC score	0.541233 (rank : 216)
Query Neighborhood Hits	747	Target Neighborhood Hits	395	Shared Neighborhood Hits	270
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

EPHA2_HUMAN
θ value	9.92553e-07 (rank : 180)	NC score	0.104268 (rank : 365)
Query Neighborhood Hits	747	Target Neighborhood Hits	1021	Shared Neighborhood Hits	89
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

LRRK1_MOUSE
θ value	9.92553e-07 (rank : 181)	NC score	0.132251 (rank : 310)
Query Neighborhood Hits	747	Target Neighborhood Hits	1267	Shared Neighborhood Hits	172
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NFKB2_HUMAN
θ value	9.92553e-07 (rank : 182)	NC score	0.692577 (rank : 165)
Query Neighborhood Hits	747	Target Neighborhood Hits	325	Shared Neighborhood Hits	283
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

OSTF1_MOUSE
θ value	9.92553e-07 (rank : 183)	NC score	0.660343 (rank : 175)
Query Neighborhood Hits	747	Target Neighborhood Hits	467	Shared Neighborhood Hits	299
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

TCGAP_HUMAN
θ value	9.92553e-07 (rank : 184)	NC score	0.084548 (rank : 431)
Query Neighborhood Hits	747	Target Neighborhood Hits	872	Shared Neighborhood Hits	182
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

OGFR_HUMAN
θ value	1.29631e-06 (rank : 185)	NC score	0.125521 (rank : 315)
Query Neighborhood Hits	747	Target Neighborhood Hits	1582	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ANKY2_HUMAN
θ value	1.69304e-06 (rank : 186)	NC score	0.727945 (rank : 151)
Query Neighborhood Hits	747	Target Neighborhood Hits	306	Shared Neighborhood Hits	260
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANS4B_MOUSE
θ value	1.69304e-06 (rank : 187)	NC score	0.738486 (rank : 147)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

EPHA2_MOUSE
θ value	1.69304e-06 (rank : 188)	NC score	0.104388 (rank : 363)
Query Neighborhood Hits	747	Target Neighborhood Hits	1020	Shared Neighborhood Hits	89
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

MAST4_HUMAN
θ value	1.69304e-06 (rank : 189)	NC score	0.056754 (rank : 678)
Query Neighborhood Hits	747	Target Neighborhood Hits	1804	Shared Neighborhood Hits	234
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NFKB2_MOUSE
θ value	1.69304e-06 (rank : 190)	NC score	0.677122 (rank : 172)
Query Neighborhood Hits	747	Target Neighborhood Hits	326	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

SNCAP_HUMAN
θ value	2.21117e-06 (rank : 191)	NC score	0.717207 (rank : 152)
Query Neighborhood Hits	747	Target Neighborhood Hits	313	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANKY2_MOUSE
θ value	2.88788e-06 (rank : 192)	NC score	0.705989 (rank : 157)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	263
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR25_HUMAN
θ value	2.88788e-06 (rank : 193)	NC score	0.666720 (rank : 174)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	272
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

RFXK_HUMAN
θ value	2.88788e-06 (rank : 194)	NC score	0.786261 (rank : 112)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	268
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

DDFL1_MOUSE
θ value	3.77169e-06 (rank : 195)	NC score	0.481749 (rank : 235)
Query Neighborhood Hits	747	Target Neighborhood Hits	324	Shared Neighborhood Hits	260
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

EPHA5_HUMAN
θ value	3.77169e-06 (rank : 196)	NC score	0.107520 (rank : 345)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHB3_HUMAN
θ value	3.77169e-06 (rank : 197)	NC score	0.105311 (rank : 354)
Query Neighborhood Hits	747	Target Neighborhood Hits	996	Shared Neighborhood Hits	90
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

MLL3_MOUSE
θ value	3.77169e-06 (rank : 198)	NC score	0.106097 (rank : 352)
Query Neighborhood Hits	747	Target Neighborhood Hits	1399	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ANR38_HUMAN
θ value	4.92598e-06 (rank : 199)	NC score	0.648768 (rank : 180)
Query Neighborhood Hits	747	Target Neighborhood Hits	443	Shared Neighborhood Hits	254
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR47_HUMAN
θ value	4.92598e-06 (rank : 200)	NC score	0.689681 (rank : 167)
Query Neighborhood Hits	747	Target Neighborhood Hits	369	Shared Neighborhood Hits	273
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

HECD1_HUMAN
θ value	4.92598e-06 (rank : 201)	NC score	0.586322 (rank : 200)
Query Neighborhood Hits	747	Target Neighborhood Hits	371	Shared Neighborhood Hits	274
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR26_HUMAN
θ value	6.43352e-06 (rank : 202)	NC score	0.419988 (rank : 253)
Query Neighborhood Hits	747	Target Neighborhood Hits	1614	Shared Neighborhood Hits	335
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASPP2_HUMAN
θ value	6.43352e-06 (rank : 203)	NC score	0.572455 (rank : 205)
Query Neighborhood Hits	747	Target Neighborhood Hits	1156	Shared Neighborhood Hits	374
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

NACAM_MOUSE
θ value	6.43352e-06 (rank : 204)	NC score	0.137573 (rank : 306)
Query Neighborhood Hits	747	Target Neighborhood Hits	1866	Shared Neighborhood Hits	288
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

AN13B_HUMAN
θ value	8.40245e-06 (rank : 205)	NC score	0.530613 (rank : 222)
Query Neighborhood Hits	747	Target Neighborhood Hits	265	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	8.40245e-06 (rank : 206)	NC score	0.531083 (rank : 221)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	251
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CDN2B_MOUSE
θ value	8.40245e-06 (rank : 207)	NC score	0.647382 (rank : 181)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

EPHB3_MOUSE
θ value	8.40245e-06 (rank : 208)	NC score	0.104078 (rank : 368)
Query Neighborhood Hits	747	Target Neighborhood Hits	996	Shared Neighborhood Hits	87
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

TRPV5_MOUSE
θ value	8.40245e-06 (rank : 209)	NC score	0.489157 (rank : 233)
Query Neighborhood Hits	747	Target Neighborhood Hits	278	Shared Neighborhood Hits	248
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

A20A1_HUMAN
θ value	1.09739e-05 (rank : 210)	NC score	0.628201 (rank : 189)
Query Neighborhood Hits	747	Target Neighborhood Hits	698	Shared Neighborhood Hits	290
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR25_MOUSE
θ value	1.09739e-05 (rank : 211)	NC score	0.657410 (rank : 177)
Query Neighborhood Hits	747	Target Neighborhood Hits	398	Shared Neighborhood Hits	284
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

EPHA1_MOUSE
θ value	1.09739e-05 (rank : 212)	NC score	0.104953 (rank : 358)
Query Neighborhood Hits	747	Target Neighborhood Hits	958	Shared Neighborhood Hits	87
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

NUD12_MOUSE
θ value	1.09739e-05 (rank : 213)	NC score	0.569305 (rank : 207)
Query Neighborhood Hits	747	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

A20A2_HUMAN
θ value	1.43324e-05 (rank : 214)	NC score	0.629068 (rank : 188)
Query Neighborhood Hits	747	Target Neighborhood Hits	716	Shared Neighborhood Hits	294
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	1.43324e-05 (rank : 215)	NC score	0.629903 (rank : 187)
Query Neighborhood Hits	747	Target Neighborhood Hits	692	Shared Neighborhood Hits	294
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.43324e-05 (rank : 216)	NC score	0.625284 (rank : 191)
Query Neighborhood Hits	747	Target Neighborhood Hits	710	Shared Neighborhood Hits	294
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

POT14_HUMAN
θ value	1.43324e-05 (rank : 217)	NC score	0.683640 (rank : 170)
Query Neighborhood Hits	747	Target Neighborhood Hits	403	Shared Neighborhood Hits	272
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

POT22_HUMAN
θ value	1.43324e-05 (rank : 218)	NC score	0.644114 (rank : 184)
Query Neighborhood Hits	747	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR37_MOUSE
θ value	1.87187e-05 (rank : 219)	NC score	0.716174 (rank : 153)
Query Neighborhood Hits	747	Target Neighborhood Hits	237	Shared Neighborhood Hits	235
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ASB1_HUMAN
θ value	1.87187e-05 (rank : 220)	NC score	0.775683 (rank : 121)
Query Neighborhood Hits	747	Target Neighborhood Hits	291	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

EPHA1_HUMAN
θ value	1.87187e-05 (rank : 221)	NC score	0.104930 (rank : 359)
Query Neighborhood Hits	747	Target Neighborhood Hits	997	Shared Neighborhood Hits	94
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA7_HUMAN
θ value	1.87187e-05 (rank : 222)	NC score	0.105309 (rank : 355)
Query Neighborhood Hits	747	Target Neighborhood Hits	1053	Shared Neighborhood Hits	94
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

ANR33_MOUSE
θ value	2.44474e-05 (rank : 223)	NC score	0.673022 (rank : 173)
Query Neighborhood Hits	747	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ASPP1_MOUSE
θ value	2.44474e-05 (rank : 224)	NC score	0.557200 (rank : 212)
Query Neighborhood Hits	747	Target Neighborhood Hits	1244	Shared Neighborhood Hits	407
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EPHA5_MOUSE
θ value	2.44474e-05 (rank : 225)	NC score	0.097873 (rank : 397)
Query Neighborhood Hits	747	Target Neighborhood Hits	950	Shared Neighborhood Hits	86
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

MTPN_HUMAN
θ value	2.44474e-05 (rank : 226)	NC score	0.798083 (rank : 99)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	2.44474e-05 (rank : 227)	NC score	0.801581 (rank : 94)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

PRRT3_HUMAN
θ value	2.44474e-05 (rank : 228)	NC score	0.121854 (rank : 322)
Query Neighborhood Hits	747	Target Neighborhood Hits	998	Shared Neighborhood Hits	183
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ANR38_MOUSE
θ value	3.19293e-05 (rank : 229)	NC score	0.624605 (rank : 192)
Query Neighborhood Hits	747	Target Neighborhood Hits	512	Shared Neighborhood Hits	257
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR45_HUMAN
θ value	3.19293e-05 (rank : 230)	NC score	0.586717 (rank : 199)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

GLSL_MOUSE
θ value	3.19293e-05 (rank : 231)	NC score	0.522995 (rank : 229)
Query Neighborhood Hits	747	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

K1802_MOUSE
θ value	3.19293e-05 (rank : 232)	NC score	0.083669 (rank : 437)
Query Neighborhood Hits	747	Target Neighborhood Hits	1596	Shared Neighborhood Hits	209
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

EPHA7_MOUSE
θ value	4.1701e-05 (rank : 233)	NC score	0.104374 (rank : 364)
Query Neighborhood Hits	747	Target Neighborhood Hits	1025	Shared Neighborhood Hits	89
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHB1_HUMAN
θ value	4.1701e-05 (rank : 234)	NC score	0.101313 (rank : 381)
Query Neighborhood Hits	747	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

ABTB2_MOUSE
θ value	5.44631e-05 (rank : 235)	NC score	0.564156 (rank : 209)
Query Neighborhood Hits	747	Target Neighborhood Hits	414	Shared Neighborhood Hits	239
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR37_HUMAN
θ value	5.44631e-05 (rank : 236)	NC score	0.729262 (rank : 150)
Query Neighborhood Hits	747	Target Neighborhood Hits	247	Shared Neighborhood Hits	245
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

CENB2_HUMAN
θ value	5.44631e-05 (rank : 237)	NC score	0.529513 (rank : 223)
Query Neighborhood Hits	747	Target Neighborhood Hits	425	Shared Neighborhood Hits	262
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

EPHB4_HUMAN
θ value	5.44631e-05 (rank : 238)	NC score	0.104256 (rank : 366)
Query Neighborhood Hits	747	Target Neighborhood Hits	1056	Shared Neighborhood Hits	94
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

NFH_MOUSE
θ value	5.44631e-05 (rank : 239)	NC score	0.086647 (rank : 420)
Query Neighborhood Hits	747	Target Neighborhood Hits	2247	Shared Neighborhood Hits	270
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ASPP1_HUMAN
θ value	7.1131e-05 (rank : 240)	NC score	0.571861 (rank : 206)
Query Neighborhood Hits	747	Target Neighborhood Hits	956	Shared Neighborhood Hits	370
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CD2A1_HUMAN
θ value	9.29e-05 (rank : 241)	NC score	0.619559 (rank : 193)
Query Neighborhood Hits	747	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

DDEF1_MOUSE
θ value	9.29e-05 (rank : 242)	NC score	0.338067 (rank : 272)
Query Neighborhood Hits	747	Target Neighborhood Hits	592	Shared Neighborhood Hits	272
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	9.29e-05 (rank : 243)	NC score	0.421918 (rank : 252)
Query Neighborhood Hits	747	Target Neighborhood Hits	599	Shared Neighborhood Hits	326
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	9.29e-05 (rank : 244)	NC score	0.418636 (rank : 254)
Query Neighborhood Hits	747	Target Neighborhood Hits	625	Shared Neighborhood Hits	331
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

LRRK1_HUMAN
θ value	9.29e-05 (rank : 245)	NC score	0.108697 (rank : 341)
Query Neighborhood Hits	747	Target Neighborhood Hits	1237	Shared Neighborhood Hits	147
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

AN13A_HUMAN
θ value	0.000121331 (rank : 246)	NC score	0.467696 (rank : 241)
Query Neighborhood Hits	747	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ASB12_HUMAN
θ value	0.000121331 (rank : 247)	NC score	0.780868 (rank : 117)
Query Neighborhood Hits	747	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

EPHB4_MOUSE
θ value	0.000121331 (rank : 248)	NC score	0.103148 (rank : 374)
Query Neighborhood Hits	747	Target Neighborhood Hits	1013	Shared Neighborhood Hits	90
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

IKBB_HUMAN
θ value	0.000121331 (rank : 249)	NC score	0.756834 (rank : 133)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

TRPV6_MOUSE
θ value	0.000121331 (rank : 250)	NC score	0.532281 (rank : 220)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR46_HUMAN
θ value	0.000158464 (rank : 251)	NC score	0.785738 (rank : 114)
Query Neighborhood Hits	747	Target Neighborhood Hits	281	Shared Neighborhood Hits	279
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

DDX51_HUMAN
θ value	0.000158464 (rank : 252)	NC score	0.021097 (rank : 970)
Query Neighborhood Hits	747	Target Neighborhood Hits	332	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

CT086_HUMAN
θ value	0.00020696 (rank : 253)	NC score	0.797263 (rank : 102)
Query Neighborhood Hits	747	Target Neighborhood Hits	277	Shared Neighborhood Hits	273
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

EPHA6_HUMAN
θ value	0.00020696 (rank : 254)	NC score	0.107095 (rank : 347)
Query Neighborhood Hits	747	Target Neighborhood Hits	959	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

RGS3_MOUSE
θ value	0.00020696 (rank : 255)	NC score	0.094919 (rank : 408)
Query Neighborhood Hits	747	Target Neighborhood Hits	1621	Shared Neighborhood Hits	243
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TXND2_HUMAN
θ value	0.00020696 (rank : 256)	NC score	0.085268 (rank : 425)
Query Neighborhood Hits	747	Target Neighborhood Hits	793	Shared Neighborhood Hits	116
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ANR41_HUMAN
θ value	0.000270298 (rank : 257)	NC score	0.740179 (rank : 145)
Query Neighborhood Hits	747	Target Neighborhood Hits	332	Shared Neighborhood Hits	268
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR45_MOUSE
θ value	0.000270298 (rank : 258)	NC score	0.627894 (rank : 190)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

EPHA6_MOUSE
θ value	0.000270298 (rank : 259)	NC score	0.105565 (rank : 353)
Query Neighborhood Hits	747	Target Neighborhood Hits	946	Shared Neighborhood Hits	80
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

IASPP_HUMAN
θ value	0.000270298 (rank : 260)	NC score	0.579567 (rank : 203)
Query Neighborhood Hits	747	Target Neighborhood Hits	688	Shared Neighborhood Hits	376
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NOTC1_MOUSE
θ value	0.000270298 (rank : 261)	NC score	0.334233 (rank : 274)
Query Neighborhood Hits	747	Target Neighborhood Hits	916	Shared Neighborhood Hits	291
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EPHB2_HUMAN
θ value	0.00035302 (rank : 262)	NC score	0.104032 (rank : 369)
Query Neighborhood Hits	747	Target Neighborhood Hits	983	Shared Neighborhood Hits	87
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.00035302 (rank : 263)	NC score	0.102649 (rank : 378)
Query Neighborhood Hits	747	Target Neighborhood Hits	982	Shared Neighborhood Hits	87
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

GLSL_HUMAN
θ value	0.00035302 (rank : 264)	NC score	0.526354 (rank : 227)
Query Neighborhood Hits	747	Target Neighborhood Hits	211	Shared Neighborhood Hits	204
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

NPAS4_MOUSE
θ value	0.00035302 (rank : 265)	NC score	0.046027 (rank : 829)
Query Neighborhood Hits	747	Target Neighborhood Hits	245	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

AN36A_HUMAN
θ value	0.000461057 (rank : 266)	NC score	0.730513 (rank : 149)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	265
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR33_HUMAN
θ value	0.000461057 (rank : 267)	NC score	0.649507 (rank : 179)
Query Neighborhood Hits	747	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR46_MOUSE
θ value	0.000461057 (rank : 268)	NC score	0.780199 (rank : 118)
Query Neighborhood Hits	747	Target Neighborhood Hits	274	Shared Neighborhood Hits	272
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CD2A1_MOUSE
θ value	0.000461057 (rank : 269)	NC score	0.685205 (rank : 169)
Query Neighborhood Hits	747	Target Neighborhood Hits	206	Shared Neighborhood Hits	205
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CENG3_HUMAN
θ value	0.000461057 (rank : 270)	NC score	0.314313 (rank : 276)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	238
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.000461057 (rank : 271)	NC score	0.314227 (rank : 277)
Query Neighborhood Hits	747	Target Neighborhood Hits	467	Shared Neighborhood Hits	237
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CT012_MOUSE
θ value	0.000461057 (rank : 272)	NC score	0.471921 (rank : 240)
Query Neighborhood Hits	747	Target Neighborhood Hits	229	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

K1543_MOUSE
θ value	0.000461057 (rank : 273)	NC score	0.095821 (rank : 404)
Query Neighborhood Hits	747	Target Neighborhood Hits	497	Shared Neighborhood Hits	110
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SON_HUMAN
θ value	0.000461057 (rank : 274)	NC score	0.107031 (rank : 348)
Query Neighborhood Hits	747	Target Neighborhood Hits	1568	Shared Neighborhood Hits	244
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NUD12_HUMAN
θ value	0.000602161 (rank : 275)	NC score	0.534818 (rank : 219)
Query Neighborhood Hits	747	Target Neighborhood Hits	222	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CSF1_HUMAN
θ value	0.000786445 (rank : 276)	NC score	0.077814 (rank : 461)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	70
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CT012_HUMAN
θ value	0.000786445 (rank : 277)	NC score	0.435143 (rank : 251)
Query Neighborhood Hits	747	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

EPHA8_HUMAN
θ value	0.000786445 (rank : 278)	NC score	0.100898 (rank : 384)
Query Neighborhood Hits	747	Target Neighborhood Hits	956	Shared Neighborhood Hits	81
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	0.000786445 (rank : 279)	NC score	0.102942 (rank : 376)
Query Neighborhood Hits	747	Target Neighborhood Hits	969	Shared Neighborhood Hits	82
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

IASPP_MOUSE
θ value	0.000786445 (rank : 280)	NC score	0.527061 (rank : 226)
Query Neighborhood Hits	747	Target Neighborhood Hits	1024	Shared Neighborhood Hits	401
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TRPV6_HUMAN
θ value	0.00102713 (rank : 281)	NC score	0.448874 (rank : 246)
Query Neighborhood Hits	747	Target Neighborhood Hits	262	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

DDFL1_HUMAN
θ value	0.00134147 (rank : 282)	NC score	0.390505 (rank : 264)
Query Neighborhood Hits	747	Target Neighborhood Hits	353	Shared Neighborhood Hits	251
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

BCL9_HUMAN
θ value	0.00175202 (rank : 283)	NC score	0.100793 (rank : 385)
Query Neighborhood Hits	747	Target Neighborhood Hits	1008	Shared Neighborhood Hits	195
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EPHAA_HUMAN
θ value	0.00175202 (rank : 284)	NC score	0.103721 (rank : 371)
Query Neighborhood Hits	747	Target Neighborhood Hits	960	Shared Neighborhood Hits	83
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

GIT2_MOUSE
θ value	0.00175202 (rank : 285)	NC score	0.497906 (rank : 232)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	258
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GLSK_HUMAN
θ value	0.00175202 (rank : 286)	NC score	0.478623 (rank : 237)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GRAP_HUMAN
θ value	0.00175202 (rank : 287)	NC score	0.054622 (rank : 735)
Query Neighborhood Hits	747	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SNPC4_HUMAN
θ value	0.00175202 (rank : 288)	NC score	0.070917 (rank : 494)
Query Neighborhood Hits	747	Target Neighborhood Hits	589	Shared Neighborhood Hits	117
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

EPHB6_MOUSE
θ value	0.00228821 (rank : 289)	NC score	0.107645 (rank : 344)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	87
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

LAD1_MOUSE
θ value	0.00228821 (rank : 290)	NC score	0.084008 (rank : 434)
Query Neighborhood Hits	747	Target Neighborhood Hits	391	Shared Neighborhood Hits	76
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MLL3_HUMAN
θ value	0.00228821 (rank : 291)	NC score	0.103510 (rank : 372)
Query Neighborhood Hits	747	Target Neighborhood Hits	1644	Shared Neighborhood Hits	222
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AN13A_MOUSE
θ value	0.00298849 (rank : 292)	NC score	0.440119 (rank : 249)
Query Neighborhood Hits	747	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

ASB14_HUMAN
θ value	0.00298849 (rank : 293)	NC score	0.528097 (rank : 225)
Query Neighborhood Hits	747	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

NCOA6_HUMAN
θ value	0.00298849 (rank : 294)	NC score	0.112309 (rank : 334)
Query Neighborhood Hits	747	Target Neighborhood Hits	1202	Shared Neighborhood Hits	216
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

AN13C_HUMAN
θ value	0.00390308 (rank : 295)	NC score	0.519260 (rank : 230)
Query Neighborhood Hits	747	Target Neighborhood Hits	241	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
θ value	0.00390308 (rank : 296)	NC score	0.508493 (rank : 231)
Query Neighborhood Hits	747	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR43_MOUSE
θ value	0.00390308 (rank : 297)	NC score	0.594509 (rank : 195)
Query Neighborhood Hits	747	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

GIT2_HUMAN
θ value	0.00390308 (rank : 298)	NC score	0.463073 (rank : 243)
Query Neighborhood Hits	747	Target Neighborhood Hits	381	Shared Neighborhood Hits	256
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ASTL_HUMAN
θ value	0.00509761 (rank : 299)	NC score	0.046847 (rank : 826)
Query Neighborhood Hits	747	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

DIDO1_HUMAN
θ value	0.00509761 (rank : 300)	NC score	0.074224 (rank : 477)
Query Neighborhood Hits	747	Target Neighborhood Hits	960	Shared Neighborhood Hits	170
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ANKZ1_MOUSE
θ value	0.00665767 (rank : 301)	NC score	0.346091 (rank : 268)
Query Neighborhood Hits	747	Target Neighborhood Hits	208	Shared Neighborhood Hits	154
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CIZ1_HUMAN
θ value	0.00665767 (rank : 302)	NC score	0.078659 (rank : 458)
Query Neighborhood Hits	747	Target Neighborhood Hits	359	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

EPHB6_HUMAN
θ value	0.00665767 (rank : 303)	NC score	0.107917 (rank : 343)
Query Neighborhood Hits	747	Target Neighborhood Hits	912	Shared Neighborhood Hits	90
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

LIPB2_HUMAN
θ value	0.00665767 (rank : 304)	NC score	0.070300 (rank : 500)
Query Neighborhood Hits	747	Target Neighborhood Hits	599	Shared Neighborhood Hits	48
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

MDC1_MOUSE
θ value	0.00665767 (rank : 305)	NC score	0.106155 (rank : 351)
Query Neighborhood Hits	747	Target Neighborhood Hits	998	Shared Neighborhood Hits	180
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SASH1_HUMAN
θ value	0.00665767 (rank : 306)	NC score	0.122425 (rank : 320)
Query Neighborhood Hits	747	Target Neighborhood Hits	292	Shared Neighborhood Hits	123
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

TRPC3_HUMAN
θ value	0.00665767 (rank : 307)	NC score	0.112026 (rank : 335)
Query Neighborhood Hits	747	Target Neighborhood Hits	137	Shared Neighborhood Hits	82
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

DGKZ_MOUSE
θ value	0.00869519 (rank : 308)	NC score	0.345390 (rank : 269)
Query Neighborhood Hits	747	Target Neighborhood Hits	542	Shared Neighborhood Hits	211
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

ENAM_HUMAN
θ value	0.00869519 (rank : 309)	NC score	0.048328 (rank : 816)
Query Neighborhood Hits	747	Target Neighborhood Hits	227	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

IL4RA_MOUSE
θ value	0.00869519 (rank : 310)	NC score	0.047771 (rank : 820)
Query Neighborhood Hits	747	Target Neighborhood Hits	194	Shared Neighborhood Hits	39
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PCLO_MOUSE
θ value	0.00869519 (rank : 311)	NC score	0.104984 (rank : 357)
Query Neighborhood Hits	747	Target Neighborhood Hits	2275	Shared Neighborhood Hits	314
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RFXK_MOUSE
θ value	0.00869519 (rank : 312)	NC score	0.766998 (rank : 128)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

SARM1_MOUSE
θ value	0.00869519 (rank : 313)	NC score	0.108467 (rank : 342)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SASH1_MOUSE
θ value	0.00869519 (rank : 314)	NC score	0.124195 (rank : 318)
Query Neighborhood Hits	747	Target Neighborhood Hits	263	Shared Neighborhood Hits	96
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

TRPV5_HUMAN
θ value	0.00869519 (rank : 315)	NC score	0.443956 (rank : 248)
Query Neighborhood Hits	747	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

CLR59_HUMAN
θ value	0.0113563 (rank : 316)	NC score	0.297721 (rank : 280)
Query Neighborhood Hits	747	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CO5A2_HUMAN
θ value	0.0113563 (rank : 317)	NC score	0.054675 (rank : 734)
Query Neighborhood Hits	747	Target Neighborhood Hits	760	Shared Neighborhood Hits	154
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

EPHA4_HUMAN
θ value	0.0113563 (rank : 318)	NC score	0.099116 (rank : 395)
Query Neighborhood Hits	747	Target Neighborhood Hits	975	Shared Neighborhood Hits	85
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

GP124_MOUSE
θ value	0.0113563 (rank : 319)	NC score	0.009520 (rank : 1026)
Query Neighborhood Hits	747	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

JPH2_HUMAN
θ value	0.0113563 (rank : 320)	NC score	0.048323 (rank : 817)
Query Neighborhood Hits	747	Target Neighborhood Hits	639	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LIPB2_MOUSE
θ value	0.0113563 (rank : 321)	NC score	0.071043 (rank : 492)
Query Neighborhood Hits	747	Target Neighborhood Hits	570	Shared Neighborhood Hits	58
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

SAM14_MOUSE
θ value	0.0113563 (rank : 322)	NC score	0.096113 (rank : 401)
Query Neighborhood Hits	747	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

TEX14_MOUSE
θ value	0.0113563 (rank : 323)	NC score	0.406598 (rank : 256)
Query Neighborhood Hits	747	Target Neighborhood Hits	1333	Shared Neighborhood Hits	327
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRPC7_HUMAN
θ value	0.0113563 (rank : 324)	NC score	0.099258 (rank : 393)
Query Neighborhood Hits	747	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

CEL_HUMAN
θ value	0.0148317 (rank : 325)	NC score	0.052214 (rank : 775)
Query Neighborhood Hits	747	Target Neighborhood Hits	896	Shared Neighborhood Hits	146
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EPHA4_MOUSE
θ value	0.0148317 (rank : 326)	NC score	0.099320 (rank : 392)
Query Neighborhood Hits	747	Target Neighborhood Hits	982	Shared Neighborhood Hits	86
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

SARM1_HUMAN
θ value	0.0148317 (rank : 327)	NC score	0.095213 (rank : 406)
Query Neighborhood Hits	747	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

STAM1_HUMAN
θ value	0.0148317 (rank : 328)	NC score	0.068730 (rank : 515)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

BAZ2A_MOUSE
θ value	0.0193708 (rank : 329)	NC score	0.050118 (rank : 804)
Query Neighborhood Hits	747	Target Neighborhood Hits	744	Shared Neighborhood Hits	117
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCL9_MOUSE
θ value	0.0193708 (rank : 330)	NC score	0.104096 (rank : 367)
Query Neighborhood Hits	747	Target Neighborhood Hits	770	Shared Neighborhood Hits	173
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

GIT1_HUMAN
θ value	0.0193708 (rank : 331)	NC score	0.477721 (rank : 238)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	252
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.0193708 (rank : 332)	NC score	0.478829 (rank : 236)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	255
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

MYO9B_HUMAN
θ value	0.0193708 (rank : 333)	NC score	0.029111 (rank : 933)
Query Neighborhood Hits	747	Target Neighborhood Hits	641	Shared Neighborhood Hits	114
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RGS3_HUMAN
θ value	0.0193708 (rank : 334)	NC score	0.067261 (rank : 527)
Query Neighborhood Hits	747	Target Neighborhood Hits	1375	Shared Neighborhood Hits	187
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SAM14_HUMAN
θ value	0.0193708 (rank : 335)	NC score	0.091861 (rank : 409)
Query Neighborhood Hits	747	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

STAC_HUMAN
θ value	0.0193708 (rank : 336)	NC score	0.068242 (rank : 518)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	58
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TRPV2_MOUSE
θ value	0.0193708 (rank : 337)	NC score	0.164392 (rank : 299)
Query Neighborhood Hits	747	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CENB1_HUMAN
θ value	0.0252991 (rank : 338)	NC score	0.528270 (rank : 224)
Query Neighborhood Hits	747	Target Neighborhood Hits	383	Shared Neighborhood Hits	267
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

LCP2_HUMAN
θ value	0.0252991 (rank : 339)	NC score	0.073523 (rank : 480)
Query Neighborhood Hits	747	Target Neighborhood Hits	531	Shared Neighborhood Hits	96
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MINT_MOUSE
θ value	0.0252991 (rank : 340)	NC score	0.069805 (rank : 502)
Query Neighborhood Hits	747	Target Neighborhood Hits	1514	Shared Neighborhood Hits	206
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

STAC_MOUSE
θ value	0.0252991 (rank : 341)	NC score	0.068805 (rank : 514)
Query Neighborhood Hits	747	Target Neighborhood Hits	268	Shared Neighborhood Hits	59
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_MOUSE
θ value	0.0252991 (rank : 342)	NC score	0.069693 (rank : 506)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ANR43_HUMAN
θ value	0.0330416 (rank : 343)	NC score	0.593824 (rank : 196)
Query Neighborhood Hits	747	Target Neighborhood Hits	209	Shared Neighborhood Hits	203
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ASB6_HUMAN
θ value	0.0330416 (rank : 344)	NC score	0.686233 (rank : 168)
Query Neighborhood Hits	747	Target Neighborhood Hits	256	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CASC3_MOUSE
θ value	0.0330416 (rank : 345)	NC score	0.056727 (rank : 682)
Query Neighborhood Hits	747	Target Neighborhood Hits	333	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CNKR2_HUMAN
θ value	0.0330416 (rank : 346)	NC score	0.069729 (rank : 505)
Query Neighborhood Hits	747	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.0330416 (rank : 347)	NC score	0.069791 (rank : 503)
Query Neighborhood Hits	747	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CO9A1_MOUSE
θ value	0.0330416 (rank : 348)	NC score	0.038455 (rank : 870)
Query Neighborhood Hits	747	Target Neighborhood Hits	477	Shared Neighborhood Hits	101
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DMRTD_HUMAN
θ value	0.0330416 (rank : 349)	NC score	0.058708 (rank : 635)
Query Neighborhood Hits	747	Target Neighborhood Hits	216	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

GRIN1_MOUSE
θ value	0.0330416 (rank : 350)	NC score	0.082159 (rank : 442)
Query Neighborhood Hits	747	Target Neighborhood Hits	337	Shared Neighborhood Hits	104
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IC1_MOUSE
θ value	0.0330416 (rank : 351)	NC score	0.008219 (rank : 1037)
Query Neighborhood Hits	747	Target Neighborhood Hits	164	Shared Neighborhood Hits	18
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

MDC1_HUMAN
θ value	0.0330416 (rank : 352)	NC score	0.119713 (rank : 325)
Query Neighborhood Hits	747	Target Neighborhood Hits	1446	Shared Neighborhood Hits	209
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYO15_MOUSE
θ value	0.0330416 (rank : 353)	NC score	0.029650 (rank : 928)
Query Neighborhood Hits	747	Target Neighborhood Hits	467	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OGFR_MOUSE
θ value	0.0330416 (rank : 354)	NC score	0.073139 (rank : 484)
Query Neighborhood Hits	747	Target Neighborhood Hits	584	Shared Neighborhood Hits	90
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PHLB1_HUMAN
θ value	0.0330416 (rank : 355)	NC score	0.059544 (rank : 612)
Query Neighborhood Hits	747	Target Neighborhood Hits	1038	Shared Neighborhood Hits	126
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SAPS1_HUMAN
θ value	0.0330416 (rank : 356)	NC score	0.063272 (rank : 549)
Query Neighborhood Hits	747	Target Neighborhood Hits	704	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SRRM2_MOUSE
θ value	0.0330416 (rank : 357)	NC score	0.111610 (rank : 337)
Query Neighborhood Hits	747	Target Neighborhood Hits	1470	Shared Neighborhood Hits	235
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BSN_MOUSE
θ value	0.0431538 (rank : 358)	NC score	0.117198 (rank : 327)
Query Neighborhood Hits	747	Target Neighborhood Hits	2057	Shared Neighborhood Hits	306
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DGKI_HUMAN
θ value	0.0431538 (rank : 359)	NC score	0.342455 (rank : 270)
Query Neighborhood Hits	747	Target Neighborhood Hits	609	Shared Neighborhood Hits	227
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

MUCDL_HUMAN
θ value	0.0431538 (rank : 360)	NC score	0.086971 (rank : 418)
Query Neighborhood Hits	747	Target Neighborhood Hits	777	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PDZD2_HUMAN
θ value	0.0431538 (rank : 361)	NC score	0.047766 (rank : 821)
Query Neighborhood Hits	747	Target Neighborhood Hits	772	Shared Neighborhood Hits	122
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SON_MOUSE
θ value	0.0431538 (rank : 362)	NC score	0.091818 (rank : 410)
Query Neighborhood Hits	747	Target Neighborhood Hits	957	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TRPC7_MOUSE
θ value	0.0431538 (rank : 363)	NC score	0.097740 (rank : 398)
Query Neighborhood Hits	747	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

ULK1_MOUSE
θ value	0.0431538 (rank : 364)	NC score	0.045877 (rank : 830)
Query Neighborhood Hits	747	Target Neighborhood Hits	1214	Shared Neighborhood Hits	135
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

CDN2B_HUMAN
θ value	0.0563607 (rank : 365)	NC score	0.593627 (rank : 198)
Query Neighborhood Hits	747	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CEND3_HUMAN
θ value	0.0563607 (rank : 366)	NC score	0.106215 (rank : 350)
Query Neighborhood Hits	747	Target Neighborhood Hits	275	Shared Neighborhood Hits	108
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CO7A1_HUMAN
θ value	0.0563607 (rank : 367)	NC score	0.049871 (rank : 810)
Query Neighborhood Hits	747	Target Neighborhood Hits	807	Shared Neighborhood Hits	173
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

GRAP_MOUSE
θ value	0.0563607 (rank : 368)	NC score	0.049456 (rank : 811)
Query Neighborhood Hits	747	Target Neighborhood Hits	309	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

PKHA6_HUMAN
θ value	0.0563607 (rank : 369)	NC score	0.054862 (rank : 727)
Query Neighborhood Hits	747	Target Neighborhood Hits	556	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHG4_HUMAN
θ value	0.0563607 (rank : 370)	NC score	0.029898 (rank : 926)
Query Neighborhood Hits	747	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

SEM6B_MOUSE
θ value	0.0563607 (rank : 371)	NC score	0.014467 (rank : 1003)
Query Neighborhood Hits	747	Target Neighborhood Hits	200	Shared Neighborhood Hits	45
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

TRPC3_MOUSE
θ value	0.0563607 (rank : 372)	NC score	0.102145 (rank : 380)
Query Neighborhood Hits	747	Target Neighborhood Hits	131	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPV2_HUMAN
θ value	0.0563607 (rank : 373)	NC score	0.206831 (rank : 291)
Query Neighborhood Hits	747	Target Neighborhood Hits	130	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ZN516_MOUSE
θ value	0.0563607 (rank : 374)	NC score	0.006182 (rank : 1047)
Query Neighborhood Hits	747	Target Neighborhood Hits	1197	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

B4GT1_HUMAN
θ value	0.0736092 (rank : 375)	NC score	0.014453 (rank : 1004)
Query Neighborhood Hits	747	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CDAN1_HUMAN
θ value	0.0736092 (rank : 376)	NC score	0.052526 (rank : 772)
Query Neighborhood Hits	747	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

CTDP1_HUMAN
θ value	0.0736092 (rank : 377)	NC score	0.070691 (rank : 496)
Query Neighborhood Hits	747	Target Neighborhood Hits	416	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

EPN2_HUMAN
θ value	0.0736092 (rank : 378)	NC score	0.031264 (rank : 917)
Query Neighborhood Hits	747	Target Neighborhood Hits	156	Shared Neighborhood Hits	44
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

SHAN2_HUMAN
θ value	0.0736092 (rank : 379)	NC score	0.114062 (rank : 329)
Query Neighborhood Hits	747	Target Neighborhood Hits	346	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0736092 (rank : 380)	NC score	0.120451 (rank : 324)
Query Neighborhood Hits	747	Target Neighborhood Hits	446	Shared Neighborhood Hits	134
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

TRPC6_HUMAN
θ value	0.0736092 (rank : 381)	NC score	0.127764 (rank : 313)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

CLPB_MOUSE
θ value	0.0961366 (rank : 382)	NC score	0.640407 (rank : 185)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

EP400_MOUSE
θ value	0.0961366 (rank : 383)	NC score	0.044145 (rank : 838)
Query Neighborhood Hits	747	Target Neighborhood Hits	592	Shared Neighborhood Hits	131
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPN3_MOUSE
θ value	0.0961366 (rank : 384)	NC score	0.041825 (rank : 854)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	72
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

TROAP_HUMAN
θ value	0.0961366 (rank : 385)	NC score	0.069158 (rank : 510)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	65
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ZN385_HUMAN
θ value	0.0961366 (rank : 386)	NC score	0.062394 (rank : 568)
Query Neighborhood Hits	747	Target Neighborhood Hits	614	Shared Neighborhood Hits	108
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CABIN_HUMAN
θ value	0.125558 (rank : 387)	NC score	0.080848 (rank : 450)
Query Neighborhood Hits	747	Target Neighborhood Hits	490	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAC1G_HUMAN
θ value	0.125558 (rank : 388)	NC score	0.027654 (rank : 944)
Query Neighborhood Hits	747	Target Neighborhood Hits	587	Shared Neighborhood Hits	100
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CEND3_MOUSE
θ value	0.125558 (rank : 389)	NC score	0.100377 (rank : 387)
Query Neighborhood Hits	747	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CI079_HUMAN
θ value	0.125558 (rank : 390)	NC score	0.057262 (rank : 668)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

MTSS1_MOUSE
θ value	0.125558 (rank : 391)	NC score	0.056968 (rank : 674)
Query Neighborhood Hits	747	Target Neighborhood Hits	592	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

TESK2_HUMAN
θ value	0.125558 (rank : 392)	NC score	0.052082 (rank : 778)
Query Neighborhood Hits	747	Target Neighborhood Hits	851	Shared Neighborhood Hits	66
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TM108_MOUSE
θ value	0.125558 (rank : 393)	NC score	0.081635 (rank : 446)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TULP4_HUMAN
θ value	0.125558 (rank : 394)	NC score	0.047193 (rank : 823)
Query Neighborhood Hits	747	Target Neighborhood Hits	426	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UBP42_HUMAN
θ value	0.125558 (rank : 395)	NC score	0.031535 (rank : 913)
Query Neighborhood Hits	747	Target Neighborhood Hits	445	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

DGKZ_HUMAN
θ value	0.163984 (rank : 396)	NC score	0.360817 (rank : 265)
Query Neighborhood Hits	747	Target Neighborhood Hits	551	Shared Neighborhood Hits	223
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

MYO15_HUMAN
θ value	0.163984 (rank : 397)	NC score	0.032933 (rank : 904)
Query Neighborhood Hits	747	Target Neighborhood Hits	671	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_MOUSE
θ value	0.163984 (rank : 398)	NC score	0.103415 (rank : 373)
Query Neighborhood Hits	747	Target Neighborhood Hits	1076	Shared Neighborhood Hits	194
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OBSCN_HUMAN
θ value	0.163984 (rank : 399)	NC score	0.030912 (rank : 921)
Query Neighborhood Hits	747	Target Neighborhood Hits	1931	Shared Neighborhood Hits	194
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PSL1_HUMAN
θ value	0.163984 (rank : 400)	NC score	0.051181 (rank : 789)
Query Neighborhood Hits	747	Target Neighborhood Hits	650	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TEX14_HUMAN
θ value	0.163984 (rank : 401)	NC score	0.405954 (rank : 257)
Query Neighborhood Hits	747	Target Neighborhood Hits	1103	Shared Neighborhood Hits	304
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR40_HUMAN
θ value	0.21417 (rank : 402)	NC score	0.557606 (rank : 211)
Query Neighborhood Hits	747	Target Neighborhood Hits	224	Shared Neighborhood Hits	210
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	0.21417 (rank : 403)	NC score	0.555557 (rank : 215)
Query Neighborhood Hits	747	Target Neighborhood Hits	228	Shared Neighborhood Hits	212
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ASB6_MOUSE
θ value	0.21417 (rank : 404)	NC score	0.678941 (rank : 171)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASXL1_HUMAN
θ value	0.21417 (rank : 405)	NC score	0.037792 (rank : 877)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CLPB_HUMAN
θ value	0.21417 (rank : 406)	NC score	0.556172 (rank : 213)
Query Neighborhood Hits	747	Target Neighborhood Hits	265	Shared Neighborhood Hits	233
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

COIA1_HUMAN
θ value	0.21417 (rank : 407)	NC score	0.064629 (rank : 538)
Query Neighborhood Hits	747	Target Neighborhood Hits	447	Shared Neighborhood Hits	138
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PAK4_MOUSE
θ value	0.21417 (rank : 408)	NC score	0.040034 (rank : 864)
Query Neighborhood Hits	747	Target Neighborhood Hits	1098	Shared Neighborhood Hits	143
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SPEG_HUMAN
θ value	0.21417 (rank : 409)	NC score	0.040435 (rank : 859)
Query Neighborhood Hits	747	Target Neighborhood Hits	1762	Shared Neighborhood Hits	244
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TARA_MOUSE
θ value	0.21417 (rank : 410)	NC score	0.062609 (rank : 561)
Query Neighborhood Hits	747	Target Neighborhood Hits	1133	Shared Neighborhood Hits	149
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TLE1_MOUSE
θ value	0.21417 (rank : 411)	NC score	0.015637 (rank : 998)
Query Neighborhood Hits	747	Target Neighborhood Hits	491	Shared Neighborhood Hits	62
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ANKY1_HUMAN
θ value	0.279714 (rank : 412)	NC score	0.525636 (rank : 228)
Query Neighborhood Hits	747	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

CHIT1_MOUSE
θ value	0.279714 (rank : 413)	NC score	0.008574 (rank : 1033)
Query Neighborhood Hits	747	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

DGKD_HUMAN
θ value	0.279714 (rank : 414)	NC score	0.082059 (rank : 444)
Query Neighborhood Hits	747	Target Neighborhood Hits	231	Shared Neighborhood Hits	68
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

FOG1_HUMAN
θ value	0.279714 (rank : 415)	NC score	0.020517 (rank : 974)
Query Neighborhood Hits	747	Target Neighborhood Hits	981	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GNAS1_MOUSE
θ value	0.279714 (rank : 416)	NC score	0.038543 (rank : 869)
Query Neighborhood Hits	747	Target Neighborhood Hits	651	Shared Neighborhood Hits	127
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IWS1_MOUSE
θ value	0.279714 (rank : 417)	NC score	0.068389 (rank : 516)
Query Neighborhood Hits	747	Target Neighborhood Hits	1258	Shared Neighborhood Hits	151
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MEGF9_MOUSE
θ value	0.279714 (rank : 418)	NC score	0.054786 (rank : 729)
Query Neighborhood Hits	747	Target Neighborhood Hits	896	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PAR6A_HUMAN
θ value	0.279714 (rank : 419)	NC score	0.017099 (rank : 991)
Query Neighborhood Hits	747	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PEX13_MOUSE
θ value	0.279714 (rank : 420)	NC score	0.032739 (rank : 907)
Query Neighborhood Hits	747	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

YLPM1_HUMAN
θ value	0.279714 (rank : 421)	NC score	0.097500 (rank : 399)
Query Neighborhood Hits	747	Target Neighborhood Hits	670	Shared Neighborhood Hits	162
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZN409_HUMAN
θ value	0.279714 (rank : 422)	NC score	0.017911 (rank : 987)
Query Neighborhood Hits	747	Target Neighborhood Hits	842	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

CENG2_HUMAN
θ value	0.365318 (rank : 423)	NC score	0.340861 (rank : 271)
Query Neighborhood Hits	747	Target Neighborhood Hits	471	Shared Neighborhood Hits	260
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CUTL2_HUMAN
θ value	0.365318 (rank : 424)	NC score	0.032117 (rank : 910)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	105
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DAB1_HUMAN
θ value	0.365318 (rank : 425)	NC score	0.045123 (rank : 833)
Query Neighborhood Hits	747	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DOCK4_MOUSE
θ value	0.365318 (rank : 426)	NC score	0.022663 (rank : 964)
Query Neighborhood Hits	747	Target Neighborhood Hits	210	Shared Neighborhood Hits	52
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

ITSN1_MOUSE
θ value	0.365318 (rank : 427)	NC score	0.048737 (rank : 814)
Query Neighborhood Hits	747	Target Neighborhood Hits	1669	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LIPB1_HUMAN
θ value	0.365318 (rank : 428)	NC score	0.058445 (rank : 640)
Query Neighborhood Hits	747	Target Neighborhood Hits	640	Shared Neighborhood Hits	61
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

PCLO_HUMAN
θ value	0.365318 (rank : 429)	NC score	0.112385 (rank : 333)
Query Neighborhood Hits	747	Target Neighborhood Hits	2046	Shared Neighborhood Hits	304
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RP1L1_HUMAN
θ value	0.365318 (rank : 430)	NC score	0.077758 (rank : 462)
Query Neighborhood Hits	747	Target Neighborhood Hits	1072	Shared Neighborhood Hits	177
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

STAM2_HUMAN
θ value	0.365318 (rank : 431)	NC score	0.054979 (rank : 724)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

UBP43_HUMAN
θ value	0.365318 (rank : 432)	NC score	0.014503 (rank : 1002)
Query Neighborhood Hits	747	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

ADA12_MOUSE
θ value	0.47712 (rank : 433)	NC score	0.014938 (rank : 1001)
Query Neighborhood Hits	747	Target Neighborhood Hits	474	Shared Neighborhood Hits	72
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BAT2_HUMAN
θ value	0.47712 (rank : 434)	NC score	0.128219 (rank : 312)
Query Neighborhood Hits	747	Target Neighborhood Hits	931	Shared Neighborhood Hits	227
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	0.47712 (rank : 435)	NC score	0.111743 (rank : 336)
Query Neighborhood Hits	747	Target Neighborhood Hits	947	Shared Neighborhood Hits	233
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENG2_MOUSE
θ value	0.47712 (rank : 436)	NC score	0.337975 (rank : 273)
Query Neighborhood Hits	747	Target Neighborhood Hits	463	Shared Neighborhood Hits	256
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENPF_HUMAN
θ value	0.47712 (rank : 437)	NC score	0.029086 (rank : 934)
Query Neighborhood Hits	747	Target Neighborhood Hits	1932	Shared Neighborhood Hits	103
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CONA1_HUMAN
θ value	0.47712 (rank : 438)	NC score	0.035829 (rank : 893)
Query Neighborhood Hits	747	Target Neighborhood Hits	281	Shared Neighborhood Hits	87
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

EGR4_HUMAN
θ value	0.47712 (rank : 439)	NC score	-0.008351 (rank : 1078)
Query Neighborhood Hits	747	Target Neighborhood Hits	939	Shared Neighborhood Hits	62
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

HAIR_HUMAN
θ value	0.47712 (rank : 440)	NC score	0.030967 (rank : 919)
Query Neighborhood Hits	747	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

JADE2_MOUSE
θ value	0.47712 (rank : 441)	NC score	0.038845 (rank : 868)
Query Neighborhood Hits	747	Target Neighborhood Hits	560	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K0423_HUMAN
θ value	0.47712 (rank : 442)	NC score	0.028072 (rank : 940)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

LPP_HUMAN
θ value	0.47712 (rank : 443)	NC score	0.030379 (rank : 924)
Query Neighborhood Hits	747	Target Neighborhood Hits	775	Shared Neighborhood Hits	120
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGD4_HUMAN
θ value	0.47712 (rank : 444)	NC score	0.032798 (rank : 906)
Query Neighborhood Hits	747	Target Neighborhood Hits	338	Shared Neighborhood Hits	70
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

OBF1_HUMAN
θ value	0.47712 (rank : 445)	NC score	0.034043 (rank : 901)
Query Neighborhood Hits	747	Target Neighborhood Hits	203	Shared Neighborhood Hits	43
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

SRRM1_MOUSE
θ value	0.47712 (rank : 446)	NC score	0.136128 (rank : 308)
Query Neighborhood Hits	747	Target Neighborhood Hits	966	Shared Neighborhood Hits	193
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYP2L_HUMAN
θ value	0.47712 (rank : 447)	NC score	0.063138 (rank : 551)
Query Neighborhood Hits	747	Target Neighborhood Hits	400	Shared Neighborhood Hits	127
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TLE1_HUMAN
θ value	0.47712 (rank : 448)	NC score	0.016199 (rank : 994)
Query Neighborhood Hits	747	Target Neighborhood Hits	485	Shared Neighborhood Hits	62
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TM108_HUMAN
θ value	0.47712 (rank : 449)	NC score	0.080959 (rank : 449)
Query Neighborhood Hits	747	Target Neighborhood Hits	166	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TNK1_HUMAN
θ value	0.47712 (rank : 450)	NC score	0.065246 (rank : 536)
Query Neighborhood Hits	747	Target Neighborhood Hits	815	Shared Neighborhood Hits	77
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

ARMX2_MOUSE
θ value	0.62314 (rank : 451)	NC score	0.044743 (rank : 834)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	74
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

BAZ2A_HUMAN
θ value	0.62314 (rank : 452)	NC score	0.038339 (rank : 872)
Query Neighborhood Hits	747	Target Neighborhood Hits	780	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

C2TA_HUMAN
θ value	0.62314 (rank : 453)	NC score	0.031880 (rank : 911)
Query Neighborhood Hits	747	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

DOCK4_HUMAN
θ value	0.62314 (rank : 454)	NC score	0.025615 (rank : 952)
Query Neighborhood Hits	747	Target Neighborhood Hits	237	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

LIPB1_MOUSE
θ value	0.62314 (rank : 455)	NC score	0.055504 (rank : 716)
Query Neighborhood Hits	747	Target Neighborhood Hits	727	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MTSS1_HUMAN
θ value	0.62314 (rank : 456)	NC score	0.045143 (rank : 832)
Query Neighborhood Hits	747	Target Neighborhood Hits	504	Shared Neighborhood Hits	88
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NFRKB_MOUSE
θ value	0.62314 (rank : 457)	NC score	0.048562 (rank : 815)
Query Neighborhood Hits	747	Target Neighborhood Hits	393	Shared Neighborhood Hits	83
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NSD1_HUMAN
θ value	0.62314 (rank : 458)	NC score	0.047705 (rank : 822)
Query Neighborhood Hits	747	Target Neighborhood Hits	427	Shared Neighborhood Hits	74
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PAF49_MOUSE
θ value	0.62314 (rank : 459)	NC score	0.021037 (rank : 972)
Query Neighborhood Hits	747	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

STAM2_MOUSE
θ value	0.62314 (rank : 460)	NC score	0.056859 (rank : 676)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	55
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TCF20_HUMAN
θ value	0.62314 (rank : 461)	NC score	0.039835 (rank : 865)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TENX_HUMAN
θ value	0.62314 (rank : 462)	NC score	0.041990 (rank : 852)
Query Neighborhood Hits	747	Target Neighborhood Hits	789	Shared Neighborhood Hits	66
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TRPC6_MOUSE
θ value	0.62314 (rank : 463)	NC score	0.099505 (rank : 391)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TSC1_HUMAN
θ value	0.62314 (rank : 464)	NC score	0.027683 (rank : 943)
Query Neighborhood Hits	747	Target Neighborhood Hits	765	Shared Neighborhood Hits	63
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ZIMP7_MOUSE
θ value	0.62314 (rank : 465)	NC score	0.049183 (rank : 812)
Query Neighborhood Hits	747	Target Neighborhood Hits	566	Shared Neighborhood Hits	112
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN687_HUMAN
θ value	0.62314 (rank : 466)	NC score	0.013430 (rank : 1011)
Query Neighborhood Hits	747	Target Neighborhood Hits	1244	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ACK1_MOUSE
θ value	0.813845 (rank : 467)	NC score	0.071955 (rank : 489)
Query Neighborhood Hits	747	Target Neighborhood Hits	1080	Shared Neighborhood Hits	160
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ATX7_MOUSE
θ value	0.813845 (rank : 468)	NC score	0.034737 (rank : 899)
Query Neighborhood Hits	747	Target Neighborhood Hits	328	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CEND1_HUMAN
θ value	0.813845 (rank : 469)	NC score	0.086416 (rank : 422)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	0.813845 (rank : 470)	NC score	0.080358 (rank : 453)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CENG1_HUMAN
θ value	0.813845 (rank : 471)	NC score	0.350814 (rank : 267)
Query Neighborhood Hits	747	Target Neighborhood Hits	544	Shared Neighborhood Hits	302
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CEP68_HUMAN
θ value	0.813845 (rank : 472)	NC score	0.025194 (rank : 953)
Query Neighborhood Hits	747	Target Neighborhood Hits	128	Shared Neighborhood Hits	29
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CGRE1_HUMAN
θ value	0.813845 (rank : 473)	NC score	0.040757 (rank : 857)
Query Neighborhood Hits	747	Target Neighborhood Hits	354	Shared Neighborhood Hits	61
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CO9A1_HUMAN
θ value	0.813845 (rank : 474)	NC score	0.038996 (rank : 867)
Query Neighborhood Hits	747	Target Neighborhood Hits	420	Shared Neighborhood Hits	98
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DCBD1_MOUSE
θ value	0.813845 (rank : 475)	NC score	0.006935 (rank : 1044)
Query Neighborhood Hits	747	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

FBX46_MOUSE
θ value	0.813845 (rank : 476)	NC score	0.020071 (rank : 977)
Query Neighborhood Hits	747	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FOXH1_HUMAN
θ value	0.813845 (rank : 477)	NC score	0.007861 (rank : 1040)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

FYB_HUMAN
θ value	0.813845 (rank : 478)	NC score	0.072049 (rank : 488)
Query Neighborhood Hits	747	Target Neighborhood Hits	379	Shared Neighborhood Hits	98
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GRAP2_HUMAN
θ value	0.813845 (rank : 479)	NC score	0.042379 (rank : 850)
Query Neighborhood Hits	747	Target Neighborhood Hits	304	Shared Neighborhood Hits	59
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	0.813845 (rank : 480)	NC score	0.042469 (rank : 849)
Query Neighborhood Hits	747	Target Neighborhood Hits	297	Shared Neighborhood Hits	56
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

IWS1_HUMAN
θ value	0.813845 (rank : 481)	NC score	0.059474 (rank : 616)
Query Neighborhood Hits	747	Target Neighborhood Hits	1241	Shared Neighborhood Hits	136
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JIP3_HUMAN
θ value	0.813845 (rank : 482)	NC score	0.036091 (rank : 892)
Query Neighborhood Hits	747	Target Neighborhood Hits	1039	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MBB1A_HUMAN
θ value	0.813845 (rank : 483)	NC score	0.054871 (rank : 726)
Query Neighborhood Hits	747	Target Neighborhood Hits	665	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NADAP_HUMAN
θ value	0.813845 (rank : 484)	NC score	0.028099 (rank : 939)
Query Neighborhood Hits	747	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

P2RX2_HUMAN
θ value	0.813845 (rank : 485)	NC score	0.013239 (rank : 1013)
Query Neighborhood Hits	747	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

PEX13_HUMAN
θ value	0.813845 (rank : 486)	NC score	0.032726 (rank : 908)
Query Neighborhood Hits	747	Target Neighborhood Hits	128	Shared Neighborhood Hits	32
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

RSNL2_HUMAN
θ value	0.813845 (rank : 487)	NC score	0.244056 (rank : 284)
Query Neighborhood Hits	747	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SPEG_MOUSE
θ value	0.813845 (rank : 488)	NC score	0.043004 (rank : 845)
Query Neighborhood Hits	747	Target Neighborhood Hits	1959	Shared Neighborhood Hits	229
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TBCD4_MOUSE
θ value	0.813845 (rank : 489)	NC score	0.027579 (rank : 945)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TGON2_HUMAN
θ value	0.813845 (rank : 490)	NC score	0.074915 (rank : 473)
Query Neighborhood Hits	747	Target Neighborhood Hits	1037	Shared Neighborhood Hits	153
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AAK1_MOUSE
θ value	1.06291 (rank : 491)	NC score	0.034619 (rank : 900)
Query Neighborhood Hits	747	Target Neighborhood Hits	1051	Shared Neighborhood Hits	127
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AATK_HUMAN
θ value	1.06291 (rank : 492)	NC score	0.058161 (rank : 644)
Query Neighborhood Hits	747	Target Neighborhood Hits	1243	Shared Neighborhood Hits	149
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AMPH_HUMAN
θ value	1.06291 (rank : 493)	NC score	0.044538 (rank : 836)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	81
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ANKZ1_HUMAN
θ value	1.06291 (rank : 494)	NC score	0.323753 (rank : 275)
Query Neighborhood Hits	747	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

BAT3_HUMAN
θ value	1.06291 (rank : 495)	NC score	0.069691 (rank : 507)
Query Neighborhood Hits	747	Target Neighborhood Hits	490	Shared Neighborhood Hits	121
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BSN_HUMAN
θ value	1.06291 (rank : 496)	NC score	0.112400 (rank : 332)
Query Neighborhood Hits	747	Target Neighborhood Hits	1537	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CAC1H_MOUSE
θ value	1.06291 (rank : 497)	NC score	0.011075 (rank : 1020)
Query Neighborhood Hits	747	Target Neighborhood Hits	230	Shared Neighborhood Hits	39
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CBX4_MOUSE
θ value	1.06291 (rank : 498)	NC score	0.016594 (rank : 993)
Query Neighborhood Hits	747	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

COBA1_HUMAN
θ value	1.06291 (rank : 499)	NC score	0.045807 (rank : 831)
Query Neighborhood Hits	747	Target Neighborhood Hits	491	Shared Neighborhood Hits	124
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	1.06291 (rank : 500)	NC score	0.044546 (rank : 835)
Query Neighborhood Hits	747	Target Neighborhood Hits	487	Shared Neighborhood Hits	125
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

INP5E_HUMAN
θ value	1.06291 (rank : 501)	NC score	0.031717 (rank : 912)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

ITSN1_HUMAN
θ value	1.06291 (rank : 502)	NC score	0.044064 (rank : 839)
Query Neighborhood Hits	747	Target Neighborhood Hits	1757	Shared Neighborhood Hits	164
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
θ value	1.06291 (rank : 503)	NC score	0.037053 (rank : 886)
Query Neighborhood Hits	747	Target Neighborhood Hits	1173	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	1.06291 (rank : 504)	NC score	0.040045 (rank : 863)
Query Neighborhood Hits	747	Target Neighborhood Hits	1371	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

JIP1_MOUSE
θ value	1.06291 (rank : 505)	NC score	0.041370 (rank : 856)
Query Neighborhood Hits	747	Target Neighborhood Hits	259	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KLF17_HUMAN
θ value	1.06291 (rank : 506)	NC score	-0.007000 (rank : 1077)
Query Neighborhood Hits	747	Target Neighborhood Hits	882	Shared Neighborhood Hits	72
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

LARP4_MOUSE
θ value	1.06291 (rank : 507)	NC score	0.057681 (rank : 656)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MAST1_HUMAN
θ value	1.06291 (rank : 508)	NC score	0.032202 (rank : 909)
Query Neighborhood Hits	747	Target Neighborhood Hits	1146	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NUFP1_HUMAN
θ value	1.06291 (rank : 509)	NC score	0.023877 (rank : 959)
Query Neighborhood Hits	747	Target Neighborhood Hits	193	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PAX3_MOUSE
θ value	1.06291 (rank : 510)	NC score	0.002066 (rank : 1066)
Query Neighborhood Hits	747	Target Neighborhood Hits	478	Shared Neighborhood Hits	28
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PI5PA_HUMAN
θ value	1.06291 (rank : 511)	NC score	0.077881 (rank : 460)
Query Neighborhood Hits	747	Target Neighborhood Hits	749	Shared Neighborhood Hits	169
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA6_MOUSE
θ value	1.06291 (rank : 512)	NC score	0.056360 (rank : 695)
Query Neighborhood Hits	747	Target Neighborhood Hits	591	Shared Neighborhood Hits	97
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PROP_MOUSE
θ value	1.06291 (rank : 513)	NC score	0.007026 (rank : 1042)
Query Neighborhood Hits	747	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RAI1_MOUSE
θ value	1.06291 (rank : 514)	NC score	0.051747 (rank : 784)
Query Neighborhood Hits	747	Target Neighborhood Hits	344	Shared Neighborhood Hits	84
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RTP3_MOUSE
θ value	1.06291 (rank : 515)	NC score	0.073307 (rank : 481)
Query Neighborhood Hits	747	Target Neighborhood Hits	374	Shared Neighborhood Hits	86
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SEPT9_HUMAN
θ value	1.06291 (rank : 516)	NC score	0.033304 (rank : 902)
Query Neighborhood Hits	747	Target Neighborhood Hits	706	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SPHK2_MOUSE
θ value	1.06291 (rank : 517)	NC score	0.021053 (rank : 971)
Query Neighborhood Hits	747	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPT5H_HUMAN
θ value	1.06291 (rank : 518)	NC score	0.057531 (rank : 662)
Query Neighborhood Hits	747	Target Neighborhood Hits	436	Shared Neighborhood Hits	103
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.06291 (rank : 519)	NC score	0.057176 (rank : 671)
Query Neighborhood Hits	747	Target Neighborhood Hits	437	Shared Neighborhood Hits	103
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SSBP4_HUMAN
θ value	1.06291 (rank : 520)	NC score	0.048045 (rank : 819)
Query Neighborhood Hits	747	Target Neighborhood Hits	753	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TB182_HUMAN
θ value	1.06291 (rank : 521)	NC score	0.076352 (rank : 466)
Query Neighborhood Hits	747	Target Neighborhood Hits	414	Shared Neighborhood Hits	122
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ZSCA5_HUMAN
θ value	1.06291 (rank : 522)	NC score	-0.011919 (rank : 1082)
Query Neighborhood Hits	747	Target Neighborhood Hits	862	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

AAK1_HUMAN
θ value	1.38821 (rank : 523)	NC score	0.034856 (rank : 898)
Query Neighborhood Hits	747	Target Neighborhood Hits	1077	Shared Neighborhood Hits	136
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BCAR1_HUMAN
θ value	1.38821 (rank : 524)	NC score	0.065154 (rank : 537)
Query Neighborhood Hits	747	Target Neighborhood Hits	554	Shared Neighborhood Hits	118
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

C1QA_HUMAN
θ value	1.38821 (rank : 525)	NC score	0.015431 (rank : 1000)
Query Neighborhood Hits	747	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

CBX2_HUMAN
θ value	1.38821 (rank : 526)	NC score	0.043435 (rank : 842)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	65
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CENG1_MOUSE
θ value	1.38821 (rank : 527)	NC score	0.352642 (rank : 266)
Query Neighborhood Hits	747	Target Neighborhood Hits	531	Shared Neighborhood Hits	299
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CONA1_MOUSE
θ value	1.38821 (rank : 528)	NC score	0.037604 (rank : 879)
Query Neighborhood Hits	747	Target Neighborhood Hits	254	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CRSP7_HUMAN
θ value	1.38821 (rank : 529)	NC score	0.029869 (rank : 927)
Query Neighborhood Hits	747	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

GRIN1_HUMAN
θ value	1.38821 (rank : 530)	NC score	0.091445 (rank : 411)
Query Neighborhood Hits	747	Target Neighborhood Hits	681	Shared Neighborhood Hits	157
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HIRP3_HUMAN
θ value	1.38821 (rank : 531)	NC score	0.032838 (rank : 905)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

LIPS_HUMAN
θ value	1.38821 (rank : 532)	NC score	0.040530 (rank : 858)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	90
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LR37A_HUMAN
θ value	1.38821 (rank : 533)	NC score	0.043072 (rank : 844)
Query Neighborhood Hits	747	Target Neighborhood Hits	720	Shared Neighborhood Hits	115
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LSD1_HUMAN
θ value	1.38821 (rank : 534)	NC score	0.034933 (rank : 897)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	73
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MAST1_MOUSE
θ value	1.38821 (rank : 535)	NC score	0.030849 (rank : 922)
Query Neighborhood Hits	747	Target Neighborhood Hits	1123	Shared Neighborhood Hits	113
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MK15_HUMAN
θ value	1.38821 (rank : 536)	NC score	0.029409 (rank : 931)
Query Neighborhood Hits	747	Target Neighborhood Hits	1038	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MLL2_HUMAN
θ value	1.38821 (rank : 537)	NC score	0.109744 (rank : 339)
Query Neighborhood Hits	747	Target Neighborhood Hits	1788	Shared Neighborhood Hits	292
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SEZ6L_HUMAN
θ value	1.38821 (rank : 538)	NC score	0.012844 (rank : 1014)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ZIM10_HUMAN
θ value	1.38821 (rank : 539)	NC score	0.037831 (rank : 876)
Query Neighborhood Hits	747	Target Neighborhood Hits	577	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	1.38821 (rank : 540)	NC score	0.036277 (rank : 890)
Query Neighborhood Hits	747	Target Neighborhood Hits	430	Shared Neighborhood Hits	87
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CMTA2_MOUSE
θ value	1.81305 (rank : 541)	NC score	0.162259 (rank : 301)
Query Neighborhood Hits	747	Target Neighborhood Hits	216	Shared Neighborhood Hits	117
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DCC_MOUSE
θ value	1.81305 (rank : 542)	NC score	0.024499 (rank : 957)
Query Neighborhood Hits	747	Target Neighborhood Hits	896	Shared Neighborhood Hits	106
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DGKH_HUMAN
θ value	1.81305 (rank : 543)	NC score	0.068271 (rank : 517)
Query Neighborhood Hits	747	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

GATA5_HUMAN
θ value	1.81305 (rank : 544)	NC score	0.005962 (rank : 1051)
Query Neighborhood Hits	747	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

GOG8A_HUMAN
θ value	1.81305 (rank : 545)	NC score	0.028375 (rank : 937)
Query Neighborhood Hits	747	Target Neighborhood Hits	635	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

JIP1_HUMAN
θ value	1.81305 (rank : 546)	NC score	0.042026 (rank : 851)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

K2027_HUMAN
θ value	1.81305 (rank : 547)	NC score	0.029628 (rank : 929)
Query Neighborhood Hits	747	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MYO1F_HUMAN
θ value	1.81305 (rank : 548)	NC score	0.023820 (rank : 960)
Query Neighborhood Hits	747	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

PAX3_HUMAN
θ value	1.81305 (rank : 549)	NC score	0.001467 (rank : 1067)
Query Neighborhood Hits	747	Target Neighborhood Hits	513	Shared Neighborhood Hits	27
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PDLI7_HUMAN
θ value	1.81305 (rank : 550)	NC score	0.009832 (rank : 1023)
Query Neighborhood Hits	747	Target Neighborhood Hits	547	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PK1L1_HUMAN
θ value	1.81305 (rank : 551)	NC score	0.019023 (rank : 981)
Query Neighborhood Hits	747	Target Neighborhood Hits	140	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

SF3B1_HUMAN
θ value	1.81305 (rank : 552)	NC score	0.043559 (rank : 841)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	73
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	1.81305 (rank : 553)	NC score	0.044048 (rank : 840)
Query Neighborhood Hits	747	Target Neighborhood Hits	352	Shared Neighborhood Hits	75
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ABTB1_MOUSE
θ value	2.36792 (rank : 554)	NC score	0.281569 (rank : 281)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	178
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ACK1_HUMAN
θ value	2.36792 (rank : 555)	NC score	0.070759 (rank : 495)
Query Neighborhood Hits	747	Target Neighborhood Hits	1140	Shared Neighborhood Hits	173
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

AKAP2_HUMAN
θ value	2.36792 (rank : 556)	NC score	0.029539 (rank : 930)
Query Neighborhood Hits	747	Target Neighborhood Hits	507	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

BIM_MOUSE
θ value	2.36792 (rank : 557)	NC score	0.025015 (rank : 954)
Query Neighborhood Hits	747	Target Neighborhood Hits	124	Shared Neighborhood Hits	30
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

CIC_HUMAN
θ value	2.36792 (rank : 558)	NC score	0.083889 (rank : 435)
Query Neighborhood Hits	747	Target Neighborhood Hits	992	Shared Neighborhood Hits	218
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO002_HUMAN
θ value	2.36792 (rank : 559)	NC score	0.049960 (rank : 809)
Query Neighborhood Hits	747	Target Neighborhood Hits	387	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO4A2_MOUSE
θ value	2.36792 (rank : 560)	NC score	0.028927 (rank : 935)
Query Neighborhood Hits	747	Target Neighborhood Hits	492	Shared Neighborhood Hits	105
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

DEND_HUMAN
θ value	2.36792 (rank : 561)	NC score	0.021555 (rank : 967)
Query Neighborhood Hits	747	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

DLG4_HUMAN
θ value	2.36792 (rank : 562)	NC score	0.008449 (rank : 1034)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	41
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG5_HUMAN
θ value	2.36792 (rank : 563)	NC score	0.028757 (rank : 936)
Query Neighborhood Hits	747	Target Neighborhood Hits	1088	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DOK7_MOUSE
θ value	2.36792 (rank : 564)	NC score	0.021550 (rank : 968)
Query Neighborhood Hits	747	Target Neighborhood Hits	169	Shared Neighborhood Hits	39
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

FOXN1_MOUSE
θ value	2.36792 (rank : 565)	NC score	0.014309 (rank : 1005)
Query Neighborhood Hits	747	Target Neighborhood Hits	300	Shared Neighborhood Hits	51
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

FREA_MOUSE
θ value	2.36792 (rank : 566)	NC score	0.008244 (rank : 1036)
Query Neighborhood Hits	747	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

GP176_MOUSE
θ value	2.36792 (rank : 567)	NC score	-0.009561 (rank : 1079)
Query Neighborhood Hits	747	Target Neighborhood Hits	539	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

GR65_HUMAN
θ value	2.36792 (rank : 568)	NC score	0.030502 (rank : 923)
Query Neighborhood Hits	747	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

GRB2_HUMAN
θ value	2.36792 (rank : 569)	NC score	0.037294 (rank : 883)
Query Neighborhood Hits	747	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

HLF_MOUSE
θ value	2.36792 (rank : 570)	NC score	0.012191 (rank : 1017)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

MY18B_HUMAN
θ value	2.36792 (rank : 571)	NC score	0.029167 (rank : 932)
Query Neighborhood Hits	747	Target Neighborhood Hits	1299	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYLK_MOUSE
θ value	2.36792 (rank : 572)	NC score	0.036208 (rank : 891)
Query Neighborhood Hits	747	Target Neighborhood Hits	1489	Shared Neighborhood Hits	136
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NBR1_MOUSE
θ value	2.36792 (rank : 573)	NC score	0.024263 (rank : 958)
Query Neighborhood Hits	747	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

NRX2A_HUMAN
θ value	2.36792 (rank : 574)	NC score	0.027866 (rank : 941)
Query Neighborhood Hits	747	Target Neighborhood Hits	614	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	2.36792 (rank : 575)	NC score	0.031393 (rank : 916)
Query Neighborhood Hits	747	Target Neighborhood Hits	481	Shared Neighborhood Hits	82
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PHC2_HUMAN
θ value	2.36792 (rank : 576)	NC score	0.042817 (rank : 846)
Query Neighborhood Hits	747	Target Neighborhood Hits	388	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

RAI1_HUMAN
θ value	2.36792 (rank : 577)	NC score	0.048781 (rank : 813)
Query Neighborhood Hits	747	Target Neighborhood Hits	360	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RFIP1_MOUSE
θ value	2.36792 (rank : 578)	NC score	0.017445 (rank : 989)
Query Neighborhood Hits	747	Target Neighborhood Hits	152	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

S23IP_MOUSE
θ value	2.36792 (rank : 579)	NC score	0.075583 (rank : 468)
Query Neighborhood Hits	747	Target Neighborhood Hits	363	Shared Neighborhood Hits	100
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SAMN1_HUMAN
θ value	2.36792 (rank : 580)	NC score	0.074002 (rank : 478)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SOX13_MOUSE
θ value	2.36792 (rank : 581)	NC score	0.018347 (rank : 984)
Query Neighborhood Hits	747	Target Neighborhood Hits	495	Shared Neighborhood Hits	61
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TAF4_HUMAN
θ value	2.36792 (rank : 582)	NC score	0.137819 (rank : 305)
Query Neighborhood Hits	747	Target Neighborhood Hits	687	Shared Neighborhood Hits	193
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TDRD6_MOUSE
θ value	2.36792 (rank : 583)	NC score	0.009401 (rank : 1027)
Query Neighborhood Hits	747	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

TRPV1_MOUSE
θ value	2.36792 (rank : 584)	NC score	0.229631 (rank : 286)
Query Neighborhood Hits	747	Target Neighborhood Hits	189	Shared Neighborhood Hits	156
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

UBP53_MOUSE
θ value	2.36792 (rank : 585)	NC score	0.018377 (rank : 983)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

ZAR1_MOUSE
θ value	2.36792 (rank : 586)	NC score	0.037277 (rank : 884)
Query Neighborhood Hits	747	Target Neighborhood Hits	254	Shared Neighborhood Hits	48
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CD248_MOUSE
θ value	3.0926 (rank : 587)	NC score	0.037151 (rank : 885)
Query Neighborhood Hits	747	Target Neighborhood Hits	578	Shared Neighborhood Hits	79
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CMTA1_HUMAN
θ value	3.0926 (rank : 588)	NC score	0.201704 (rank : 293)
Query Neighborhood Hits	747	Target Neighborhood Hits	217	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	3.0926 (rank : 589)	NC score	0.175602 (rank : 296)
Query Neighborhood Hits	747	Target Neighborhood Hits	199	Shared Neighborhood Hits	123
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

COJA1_HUMAN
θ value	3.0926 (rank : 590)	NC score	0.035593 (rank : 896)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	86
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CRKL_HUMAN
θ value	3.0926 (rank : 591)	NC score	0.038175 (rank : 874)
Query Neighborhood Hits	747	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	3.0926 (rank : 592)	NC score	0.036916 (rank : 887)
Query Neighborhood Hits	747	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

FGFP3_HUMAN
θ value	3.0926 (rank : 593)	NC score	0.016779 (rank : 992)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

FOXN1_HUMAN
θ value	3.0926 (rank : 594)	NC score	0.016003 (rank : 996)
Query Neighborhood Hits	747	Target Neighborhood Hits	377	Shared Neighborhood Hits	63
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

FRS3_HUMAN
θ value	3.0926 (rank : 595)	NC score	0.015839 (rank : 997)
Query Neighborhood Hits	747	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

HASP_HUMAN
θ value	3.0926 (rank : 596)	NC score	0.008318 (rank : 1035)
Query Neighborhood Hits	747	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TF76, Q5U5K3, Q96MN1, Q9BXS7	Gene names	GSG2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (H-Haspin) (Germ cell-specific gene 2 protein).

LRSM1_HUMAN
θ value	3.0926 (rank : 597)	NC score	0.040133 (rank : 862)
Query Neighborhood Hits	747	Target Neighborhood Hits	1078	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MARCO_MOUSE
θ value	3.0926 (rank : 598)	NC score	0.014031 (rank : 1007)
Query Neighborhood Hits	747	Target Neighborhood Hits	242	Shared Neighborhood Hits	35
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

NCOA2_HUMAN
θ value	3.0926 (rank : 599)	NC score	0.021578 (rank : 966)
Query Neighborhood Hits	747	Target Neighborhood Hits	281	Shared Neighborhood Hits	44
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PP2CG_MOUSE
θ value	3.0926 (rank : 600)	NC score	0.013574 (rank : 1009)
Query Neighborhood Hits	747	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

SIM2_HUMAN
θ value	3.0926 (rank : 601)	NC score	0.006111 (rank : 1049)
Query Neighborhood Hits	747	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

STAT6_HUMAN
θ value	3.0926 (rank : 602)	NC score	0.005173 (rank : 1057)
Query Neighborhood Hits	747	Target Neighborhood Hits	132	Shared Neighborhood Hits	21
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

SYNE2_HUMAN
θ value	3.0926 (rank : 603)	NC score	0.020487 (rank : 975)
Query Neighborhood Hits	747	Target Neighborhood Hits	1323	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TACC3_HUMAN
θ value	3.0926 (rank : 604)	NC score	0.040184 (rank : 861)
Query Neighborhood Hits	747	Target Neighborhood Hits	779	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TRPC1_MOUSE
θ value	3.0926 (rank : 605)	NC score	0.055288 (rank : 720)
Query Neighborhood Hits	747	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

WWTR1_HUMAN
θ value	3.0926 (rank : 606)	NC score	0.005735 (rank : 1052)
Query Neighborhood Hits	747	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

ATF2_HUMAN
θ value	4.03905 (rank : 607)	NC score	0.028147 (rank : 938)
Query Neighborhood Hits	747	Target Neighborhood Hits	402	Shared Neighborhood Hits	55
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	4.03905 (rank : 608)	NC score	0.027298 (rank : 948)
Query Neighborhood Hits	747	Target Neighborhood Hits	397	Shared Neighborhood Hits	57
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

BANK1_MOUSE
θ value	4.03905 (rank : 609)	NC score	0.035745 (rank : 895)
Query Neighborhood Hits	747	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

CAC1A_MOUSE
θ value	4.03905 (rank : 610)	NC score	0.007935 (rank : 1038)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CEND_HUMAN
θ value	4.03905 (rank : 611)	NC score	0.037317 (rank : 882)
Query Neighborhood Hits	747	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

COBA2_MOUSE
θ value	4.03905 (rank : 612)	NC score	0.038270 (rank : 873)
Query Neighborhood Hits	747	Target Neighborhood Hits	501	Shared Neighborhood Hits	127
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

DNM3A_MOUSE
θ value	4.03905 (rank : 613)	NC score	0.012234 (rank : 1016)
Query Neighborhood Hits	747	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DOK2_MOUSE
θ value	4.03905 (rank : 614)	NC score	0.012086 (rank : 1018)
Query Neighborhood Hits	747	Target Neighborhood Hits	244	Shared Neighborhood Hits	33
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

EPHA3_HUMAN
θ value	4.03905 (rank : 615)	NC score	0.089689 (rank : 413)
Query Neighborhood Hits	747	Target Neighborhood Hits	1005	Shared Neighborhood Hits	76
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

GRB2_MOUSE
θ value	4.03905 (rank : 616)	NC score	0.036345 (rank : 889)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	51
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HCN1_MOUSE
θ value	4.03905 (rank : 617)	NC score	0.004764 (rank : 1059)
Query Neighborhood Hits	747	Target Neighborhood Hits	172	Shared Neighborhood Hits	25
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HGS_HUMAN
θ value	4.03905 (rank : 618)	NC score	0.042624 (rank : 848)
Query Neighborhood Hits	747	Target Neighborhood Hits	517	Shared Neighborhood Hits	70
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HN1L_HUMAN
θ value	4.03905 (rank : 619)	NC score	0.020909 (rank : 973)
Query Neighborhood Hits	747	Target Neighborhood Hits	88	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

HXA2_HUMAN
θ value	4.03905 (rank : 620)	NC score	-0.006648 (rank : 1076)
Query Neighborhood Hits	747	Target Neighborhood Hits	370	Shared Neighborhood Hits	17
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

HXB2_MOUSE
θ value	4.03905 (rank : 621)	NC score	-0.003526 (rank : 1074)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	22
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

K1543_HUMAN
θ value	4.03905 (rank : 622)	NC score	0.070337 (rank : 499)
Query Neighborhood Hits	747	Target Neighborhood Hits	435	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1802_HUMAN
θ value	4.03905 (rank : 623)	NC score	0.067835 (rank : 522)
Query Neighborhood Hits	747	Target Neighborhood Hits	1378	Shared Neighborhood Hits	196
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KI67_HUMAN
θ value	4.03905 (rank : 624)	NC score	0.058284 (rank : 643)
Query Neighborhood Hits	747	Target Neighborhood Hits	581	Shared Neighborhood Hits	85
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LAP2A_HUMAN
θ value	4.03905 (rank : 625)	NC score	0.006700 (rank : 1045)
Query Neighborhood Hits	747	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

LEUK_MOUSE
θ value	4.03905 (rank : 626)	NC score	0.033201 (rank : 903)
Query Neighborhood Hits	747	Target Neighborhood Hits	147	Shared Neighborhood Hits	33
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MKL1_MOUSE
θ value	4.03905 (rank : 627)	NC score	0.046967 (rank : 824)
Query Neighborhood Hits	747	Target Neighborhood Hits	667	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MYCL1_HUMAN
θ value	4.03905 (rank : 628)	NC score	0.009160 (rank : 1028)
Query Neighborhood Hits	747	Target Neighborhood Hits	146	Shared Neighborhood Hits	21
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NCOR1_HUMAN
θ value	4.03905 (rank : 629)	NC score	0.022898 (rank : 963)
Query Neighborhood Hits	747	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR2_MOUSE
θ value	4.03905 (rank : 630)	NC score	0.059741 (rank : 608)
Query Neighborhood Hits	747	Target Neighborhood Hits	790	Shared Neighborhood Hits	140
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NUMBL_HUMAN
θ value	4.03905 (rank : 631)	NC score	0.041980 (rank : 853)
Query Neighborhood Hits	747	Target Neighborhood Hits	394	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PJA1_HUMAN
θ value	4.03905 (rank : 632)	NC score	0.005463 (rank : 1056)
Query Neighborhood Hits	747	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PLRG1_HUMAN
θ value	4.03905 (rank : 633)	NC score	-0.002179 (rank : 1073)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	17
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PUNC_MOUSE
θ value	4.03905 (rank : 634)	NC score	0.004908 (rank : 1058)
Query Neighborhood Hits	747	Target Neighborhood Hits	501	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

SPHK2_HUMAN
θ value	4.03905 (rank : 635)	NC score	0.026612 (rank : 951)
Query Neighborhood Hits	747	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPR1A_MOUSE
θ value	4.03905 (rank : 636)	NC score	0.031521 (rank : 914)
Query Neighborhood Hits	747	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TAU_HUMAN
θ value	4.03905 (rank : 637)	NC score	0.069468 (rank : 509)
Query Neighborhood Hits	747	Target Neighborhood Hits	448	Shared Neighborhood Hits	126
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TINF2_HUMAN
θ value	4.03905 (rank : 638)	NC score	0.021169 (rank : 969)
Query Neighborhood Hits	747	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

TTC28_HUMAN
θ value	4.03905 (rank : 639)	NC score	0.018279 (rank : 986)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	43
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

3BP2_MOUSE
θ value	5.27518 (rank : 640)	NC score	0.027729 (rank : 942)
Query Neighborhood Hits	747	Target Neighborhood Hits	142	Shared Neighborhood Hits	37
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ARHG1_MOUSE
θ value	5.27518 (rank : 641)	NC score	0.016080 (rank : 995)
Query Neighborhood Hits	747	Target Neighborhood Hits	266	Shared Neighborhood Hits	60
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CBP_MOUSE
θ value	5.27518 (rank : 642)	NC score	0.081358 (rank : 448)
Query Neighborhood Hits	747	Target Neighborhood Hits	1051	Shared Neighborhood Hits	210
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CIC_MOUSE
θ value	5.27518 (rank : 643)	NC score	0.074911 (rank : 474)
Query Neighborhood Hits	747	Target Neighborhood Hits	742	Shared Neighborhood Hits	193
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CS007_MOUSE
θ value	5.27518 (rank : 644)	NC score	0.081577 (rank : 447)
Query Neighborhood Hits	747	Target Neighborhood Hits	464	Shared Neighborhood Hits	134
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DLG1_MOUSE
θ value	5.27518 (rank : 645)	NC score	0.007743 (rank : 1041)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	44
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

EDN3_MOUSE
θ value	5.27518 (rank : 646)	NC score	0.008647 (rank : 1032)
Query Neighborhood Hits	747	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	P48299, Q543L0	Gene names	Edn3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

EPHA3_MOUSE
θ value	5.27518 (rank : 647)	NC score	0.089469 (rank : 414)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	75
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

ERBB2_HUMAN
θ value	5.27518 (rank : 648)	NC score	0.059794 (rank : 607)
Query Neighborhood Hits	747	Target Neighborhood Hits	1073	Shared Neighborhood Hits	81
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FOG1_MOUSE
θ value	5.27518 (rank : 649)	NC score	0.019496 (rank : 980)
Query Neighborhood Hits	747	Target Neighborhood Hits	1237	Shared Neighborhood Hits	171
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXK2_HUMAN
θ value	5.27518 (rank : 650)	NC score	0.005684 (rank : 1053)
Query Neighborhood Hits	747	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

GTSE1_HUMAN
θ value	5.27518 (rank : 651)	NC score	0.043095 (rank : 843)
Query Neighborhood Hits	747	Target Neighborhood Hits	193	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HIC1_MOUSE
θ value	5.27518 (rank : 652)	NC score	-0.010171 (rank : 1080)
Query Neighborhood Hits	747	Target Neighborhood Hits	863	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

LRC56_HUMAN
θ value	5.27518 (rank : 653)	NC score	0.019790 (rank : 978)
Query Neighborhood Hits	747	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MISS_MOUSE
θ value	5.27518 (rank : 654)	NC score	0.067416 (rank : 526)
Query Neighborhood Hits	747	Target Neighborhood Hits	444	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

OSBL5_HUMAN
θ value	5.27518 (rank : 655)	NC score	0.019682 (rank : 979)
Query Neighborhood Hits	747	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

PER3_HUMAN
θ value	5.27518 (rank : 656)	NC score	0.038359 (rank : 871)
Query Neighborhood Hits	747	Target Neighborhood Hits	479	Shared Neighborhood Hits	98
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RP3A_MOUSE
θ value	5.27518 (rank : 657)	NC score	0.022998 (rank : 962)
Query Neighborhood Hits	747	Target Neighborhood Hits	510	Shared Neighborhood Hits	105
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SLY_HUMAN
θ value	5.27518 (rank : 658)	NC score	0.069037 (rank : 512)
Query Neighborhood Hits	747	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	5.27518 (rank : 659)	NC score	0.074325 (rank : 475)
Query Neighborhood Hits	747	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SYNG_MOUSE
θ value	5.27518 (rank : 660)	NC score	0.022075 (rank : 965)
Query Neighborhood Hits	747	Target Neighborhood Hits	206	Shared Neighborhood Hits	38
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TPO_MOUSE
θ value	5.27518 (rank : 661)	NC score	0.024734 (rank : 956)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	37
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

UB7I1_MOUSE
θ value	5.27518 (rank : 662)	NC score	0.013306 (rank : 1012)
Query Neighborhood Hits	747	Target Neighborhood Hits	206	Shared Neighborhood Hits	40
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UBN1_HUMAN
θ value	5.27518 (rank : 663)	NC score	0.027301 (rank : 947)
Query Neighborhood Hits	747	Target Neighborhood Hits	170	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

UBP49_HUMAN
θ value	5.27518 (rank : 664)	NC score	0.003298 (rank : 1062)
Query Neighborhood Hits	747	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

ULK1_HUMAN
θ value	5.27518 (rank : 665)	NC score	0.040414 (rank : 860)
Query Neighborhood Hits	747	Target Neighborhood Hits	1121	Shared Neighborhood Hits	132
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZBT38_HUMAN
θ value	5.27518 (rank : 666)	NC score	-0.012946 (rank : 1083)
Query Neighborhood Hits	747	Target Neighborhood Hits	885	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ZN579_HUMAN
θ value	5.27518 (rank : 667)	NC score	-0.013513 (rank : 1084)
Query Neighborhood Hits	747	Target Neighborhood Hits	726	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NAF0	Gene names	ZNF579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

ARHG6_MOUSE
θ value	6.88961 (rank : 668)	NC score	0.037534 (rank : 881)
Query Neighborhood Hits	747	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ATS14_HUMAN
θ value	6.88961 (rank : 669)	NC score	0.006146 (rank : 1048)
Query Neighborhood Hits	747	Target Neighborhood Hits	382	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

BTBDC_HUMAN
θ value	6.88961 (rank : 670)	NC score	0.038030 (rank : 875)
Query Neighborhood Hits	747	Target Neighborhood Hits	248	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CBP_HUMAN
θ value	6.88961 (rank : 671)	NC score	0.082104 (rank : 443)
Query Neighborhood Hits	747	Target Neighborhood Hits	941	Shared Neighborhood Hits	197
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	6.88961 (rank : 672)	NC score	0.044250 (rank : 837)
Query Neighborhood Hits	747	Target Neighborhood Hits	543	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CO039_MOUSE
θ value	6.88961 (rank : 673)	NC score	0.055747 (rank : 707)
Query Neighborhood Hits	747	Target Neighborhood Hits	445	Shared Neighborhood Hits	112
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CO4A2_HUMAN
θ value	6.88961 (rank : 674)	NC score	0.030263 (rank : 925)
Query Neighborhood Hits	747	Target Neighborhood Hits	454	Shared Neighborhood Hits	100
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO9A3_HUMAN
θ value	6.88961 (rank : 675)	NC score	0.035824 (rank : 894)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	95
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CRK_HUMAN
θ value	6.88961 (rank : 676)	NC score	0.039828 (rank : 866)
Query Neighborhood Hits	747	Target Neighborhood Hits	308	Shared Neighborhood Hits	57
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT174_HUMAN
θ value	6.88961 (rank : 677)	NC score	0.046572 (rank : 827)
Query Neighborhood Hits	747	Target Neighborhood Hits	181	Shared Neighborhood Hits	58
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DAB2_MOUSE
θ value	6.88961 (rank : 678)	NC score	0.048076 (rank : 818)
Query Neighborhood Hits	747	Target Neighborhood Hits	163	Shared Neighborhood Hits	51
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

FREA_HUMAN
θ value	6.88961 (rank : 679)	NC score	0.012051 (rank : 1019)
Query Neighborhood Hits	747	Target Neighborhood Hits	205	Shared Neighborhood Hits	41
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

HAIR_MOUSE
θ value	6.88961 (rank : 680)	NC score	0.017634 (rank : 988)
Query Neighborhood Hits	747	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

HGS_MOUSE
θ value	6.88961 (rank : 681)	NC score	0.042630 (rank : 847)
Query Neighborhood Hits	747	Target Neighborhood Hits	589	Shared Neighborhood Hits	88
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IPPD_MOUSE
θ value	6.88961 (rank : 682)	NC score	0.012794 (rank : 1015)
Query Neighborhood Hits	747	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60829, Q91XB5	Gene names	Ppp1r1b
Domain Architecture	No domain graphic available
Description	Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32).

IRS1_HUMAN
θ value	6.88961 (rank : 683)	NC score	0.013483 (rank : 1010)
Query Neighborhood Hits	747	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

LIPA1_HUMAN
θ value	6.88961 (rank : 684)	NC score	0.031494 (rank : 915)
Query Neighborhood Hits	747	Target Neighborhood Hits	1294	Shared Neighborhood Hits	86
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LNX2_MOUSE
θ value	6.88961 (rank : 685)	NC score	0.002617 (rank : 1063)
Query Neighborhood Hits	747	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LTBP2_MOUSE
θ value	6.88961 (rank : 686)	NC score	0.037555 (rank : 880)
Query Neighborhood Hits	747	Target Neighborhood Hits	617	Shared Neighborhood Hits	63
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOS3_HUMAN
θ value	6.88961 (rank : 687)	NC score	0.004629 (rank : 1060)
Query Neighborhood Hits	747	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

REV1_HUMAN
θ value	6.88961 (rank : 688)	NC score	0.005614 (rank : 1055)
Query Neighborhood Hits	747	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

RSNL2_MOUSE
θ value	6.88961 (rank : 689)	NC score	0.201280 (rank : 294)
Query Neighborhood Hits	747	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RT35_HUMAN
θ value	6.88961 (rank : 690)	NC score	0.008847 (rank : 1031)
Query Neighborhood Hits	747	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

SAMN1_MOUSE
θ value	6.88961 (rank : 691)	NC score	0.072449 (rank : 486)
Query Neighborhood Hits	747	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

SHC2_HUMAN
θ value	6.88961 (rank : 692)	NC score	0.018337 (rank : 985)
Query Neighborhood Hits	747	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SI1L3_HUMAN
θ value	6.88961 (rank : 693)	NC score	0.015454 (rank : 999)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	60
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SKI_HUMAN
θ value	6.88961 (rank : 694)	NC score	0.009681 (rank : 1025)
Query Neighborhood Hits	747	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SPAG8_HUMAN
θ value	6.88961 (rank : 695)	NC score	0.036914 (rank : 888)
Query Neighborhood Hits	747	Target Neighborhood Hits	56	Shared Neighborhood Hits	25
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

TCGAP_MOUSE
θ value	6.88961 (rank : 696)	NC score	0.060522 (rank : 596)
Query Neighborhood Hits	747	Target Neighborhood Hits	409	Shared Neighborhood Hits	120
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TLE3_MOUSE
θ value	6.88961 (rank : 697)	NC score	0.007907 (rank : 1039)
Query Neighborhood Hits	747	Target Neighborhood Hits	378	Shared Neighborhood Hits	36
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TRPC1_HUMAN
θ value	6.88961 (rank : 698)	NC score	0.059127 (rank : 623)
Query Neighborhood Hits	747	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPV1_HUMAN
θ value	6.88961 (rank : 699)	NC score	0.208290 (rank : 290)
Query Neighborhood Hits	747	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

UBP6_HUMAN
θ value	6.88961 (rank : 700)	NC score	0.002509 (rank : 1064)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

ZN335_HUMAN
θ value	6.88961 (rank : 701)	NC score	-0.010711 (rank : 1081)
Query Neighborhood Hits	747	Target Neighborhood Hits	973	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

AFF3_HUMAN
θ value	8.99809 (rank : 702)	NC score	0.020192 (rank : 976)
Query Neighborhood Hits	747	Target Neighborhood Hits	190	Shared Neighborhood Hits	43
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

AHI1_HUMAN
θ value	8.99809 (rank : 703)	NC score	0.031188 (rank : 918)
Query Neighborhood Hits	747	Target Neighborhood Hits	537	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

BAT3_MOUSE
θ value	8.99809 (rank : 704)	NC score	0.075422 (rank : 469)
Query Neighborhood Hits	747	Target Neighborhood Hits	518	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CCNA2_MOUSE
θ value	8.99809 (rank : 705)	NC score	-0.000547 (rank : 1072)
Query Neighborhood Hits	747	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P51943, Q61459	Gene names	Ccna2, Ccna, Cyca
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

CD248_HUMAN
θ value	8.99809 (rank : 706)	NC score	0.046036 (rank : 828)
Query Neighborhood Hits	747	Target Neighborhood Hits	679	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2_HUMAN
θ value	8.99809 (rank : 707)	NC score	0.041792 (rank : 855)
Query Neighborhood Hits	747	Target Neighborhood Hits	504	Shared Neighborhood Hits	81
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CNOT3_MOUSE
θ value	8.99809 (rank : 708)	NC score	0.060866 (rank : 588)
Query Neighborhood Hits	747	Target Neighborhood Hits	504	Shared Neighborhood Hits	109
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DCMC_HUMAN
θ value	8.99809 (rank : 709)	NC score	0.004199 (rank : 1061)
Query Neighborhood Hits	747	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O95822, Q9UNU5, Q9Y3F2	Gene names	MLYCD
Domain Architecture
Description	Malonyl-CoA decarboxylase, mitochondrial precursor (EC 4.1.1.9) (MCD).

DLG4_MOUSE
θ value	8.99809 (rank : 710)	NC score	0.005973 (rank : 1050)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	42
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DNMT1_HUMAN
θ value	8.99809 (rank : 711)	NC score	0.027068 (rank : 950)
Query Neighborhood Hits	747	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

ETV4_MOUSE
θ value	8.99809 (rank : 712)	NC score	0.001178 (rank : 1068)
Query Neighborhood Hits	747	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

GMIP_HUMAN
θ value	8.99809 (rank : 713)	NC score	0.014125 (rank : 1006)
Query Neighborhood Hits	747	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GP152_HUMAN
θ value	8.99809 (rank : 714)	NC score	0.017301 (rank : 990)
Query Neighborhood Hits	747	Target Neighborhood Hits	636	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

HRSL5_HUMAN
θ value	8.99809 (rank : 715)	NC score	0.006368 (rank : 1046)
Query Neighborhood Hits	747	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

HXC10_MOUSE
θ value	8.99809 (rank : 716)	NC score	-0.005795 (rank : 1075)
Query Neighborhood Hits	747	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

IF4G1_MOUSE
θ value	8.99809 (rank : 717)	NC score	0.046928 (rank : 825)
Query Neighborhood Hits	747	Target Neighborhood Hits	534	Shared Neighborhood Hits	111
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IKBL_HUMAN
θ value	8.99809 (rank : 718)	NC score	0.311060 (rank : 278)
Query Neighborhood Hits	747	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	8.99809 (rank : 719)	NC score	0.304101 (rank : 279)
Query Neighborhood Hits	747	Target Neighborhood Hits	196	Shared Neighborhood Hits	142
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LRC27_MOUSE
θ value	8.99809 (rank : 720)	NC score	0.001161 (rank : 1069)
Query Neighborhood Hits	747	Target Neighborhood Hits	290	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YS5, Q9D6Z2	Gene names	Lrrc27
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

MAML3_HUMAN
θ value	8.99809 (rank : 721)	NC score	0.027285 (rank : 949)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	67
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MILK1_MOUSE
θ value	8.99809 (rank : 722)	NC score	0.066905 (rank : 528)
Query Neighborhood Hits	747	Target Neighborhood Hits	788	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PHLPP_HUMAN
θ value	8.99809 (rank : 723)	NC score	0.018997 (rank : 982)
Query Neighborhood Hits	747	Target Neighborhood Hits	604	Shared Neighborhood Hits	104
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PMYT1_HUMAN
θ value	8.99809 (rank : 724)	NC score	0.023437 (rank : 961)
Query Neighborhood Hits	747	Target Neighborhood Hits	814	Shared Neighborhood Hits	61
SwissProt Accessions	Q99640, O14731, Q7LE24, Q8TCM9	Gene names	PKMYT1, MYT1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

PRD14_HUMAN
θ value	8.99809 (rank : 725)	NC score	-0.014476 (rank : 1087)
Query Neighborhood Hits	747	Target Neighborhood Hits	757	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

RIMB1_HUMAN
θ value	8.99809 (rank : 726)	NC score	0.050824 (rank : 795)
Query Neighborhood Hits	747	Target Neighborhood Hits	1479	Shared Neighborhood Hits	176
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RUSC2_MOUSE
θ value	8.99809 (rank : 727)	NC score	0.037736 (rank : 878)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	91
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SAMD4_HUMAN
θ value	8.99809 (rank : 728)	NC score	0.009798 (rank : 1024)
Query Neighborhood Hits	747	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SAMD4_MOUSE
θ value	8.99809 (rank : 729)	NC score	0.013982 (rank : 1008)
Query Neighborhood Hits	747	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SEM6B_HUMAN
θ value	8.99809 (rank : 730)	NC score	0.005659 (rank : 1054)
Query Neighborhood Hits	747	Target Neighborhood Hits	187	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SF3A2_MOUSE
θ value	8.99809 (rank : 731)	NC score	0.102883 (rank : 377)
Query Neighborhood Hits	747	Target Neighborhood Hits	247	Shared Neighborhood Hits	113
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SH3K1_HUMAN
θ value	8.99809 (rank : 732)	NC score	0.056681 (rank : 683)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	76
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	8.99809 (rank : 733)	NC score	0.054810 (rank : 728)
Query Neighborhood Hits	747	Target Neighborhood Hits	332	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SMAP1_MOUSE
θ value	8.99809 (rank : 734)	NC score	0.065844 (rank : 533)
Query Neighborhood Hits	747	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SNX25_HUMAN
θ value	8.99809 (rank : 735)	NC score	0.002159 (rank : 1065)
Query Neighborhood Hits	747	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

TAB3_MOUSE
θ value	8.99809 (rank : 736)	NC score	0.030946 (rank : 920)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TAF1C_MOUSE
θ value	8.99809 (rank : 737)	NC score	0.009134 (rank : 1029)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

TLE3_HUMAN
θ value	8.99809 (rank : 738)	NC score	0.009029 (rank : 1030)
Query Neighborhood Hits	747	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TLE4_HUMAN
θ value	8.99809 (rank : 739)	NC score	0.010356 (rank : 1022)
Query Neighborhood Hits	747	Target Neighborhood Hits	477	Shared Neighborhood Hits	56
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	8.99809 (rank : 740)	NC score	0.010774 (rank : 1021)
Query Neighborhood Hits	747	Target Neighborhood Hits	482	Shared Neighborhood Hits	58
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TSH3_HUMAN
θ value	8.99809 (rank : 741)	NC score	-0.000193 (rank : 1070)
Query Neighborhood Hits	747	Target Neighborhood Hits	564	Shared Neighborhood Hits	31
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

TXLNB_MOUSE
θ value	8.99809 (rank : 742)	NC score	0.027542 (rank : 946)
Query Neighborhood Hits	747	Target Neighborhood Hits	640	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

XKR5_HUMAN
θ value	8.99809 (rank : 743)	NC score	0.007002 (rank : 1043)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

ZBT16_HUMAN
θ value	8.99809 (rank : 744)	NC score	-0.013747 (rank : 1085)
Query Neighborhood Hits	747	Target Neighborhood Hits	1010	Shared Neighborhood Hits	54
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZHX2_MOUSE
θ value	8.99809 (rank : 745)	NC score	-0.000522 (rank : 1071)
Query Neighborhood Hits	747	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZMYM3_HUMAN
θ value	8.99809 (rank : 746)	NC score	0.024986 (rank : 955)
Query Neighborhood Hits	747	Target Neighborhood Hits	223	Shared Neighborhood Hits	49
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZN710_HUMAN
θ value	8.99809 (rank : 747)	NC score	-0.014136 (rank : 1086)
Query Neighborhood Hits	747	Target Neighborhood Hits	796	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

3BP1_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.065899 (rank : 532)
Query Neighborhood Hits	747	Target Neighborhood Hits	376	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AATK_MOUSE
θ value	θ > 10 (rank : 749)	NC score	0.058557 (rank : 637)
Query Neighborhood Hits	747	Target Neighborhood Hits	942	Shared Neighborhood Hits	123
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABI2_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.055082 (rank : 723)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABL1_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.062581 (rank : 563)
Query Neighborhood Hits	747	Target Neighborhood Hits	1220	Shared Neighborhood Hits	159
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.063765 (rank : 545)
Query Neighborhood Hits	747	Target Neighborhood Hits	1178	Shared Neighborhood Hits	161
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.057214 (rank : 669)
Query Neighborhood Hits	747	Target Neighborhood Hits	1045	Shared Neighborhood Hits	100
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABTB1_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.237275 (rank : 285)
Query Neighborhood Hits	747	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

AFF1_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.064321 (rank : 540)
Query Neighborhood Hits	747	Target Neighborhood Hits	506	Shared Neighborhood Hits	105
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF1_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.051519 (rank : 785)
Query Neighborhood Hits	747	Target Neighborhood Hits	351	Shared Neighborhood Hits	92
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALEX_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.084926 (rank : 427)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	116
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALK_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.055681 (rank : 713)
Query Neighborhood Hits	747	Target Neighborhood Hits	795	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.056437 (rank : 689)
Query Neighborhood Hits	747	Target Neighborhood Hits	811	Shared Neighborhood Hits	69
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AN13D_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.053512 (rank : 755)
Query Neighborhood Hits	747	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

AN13D_MOUSE
θ value	θ > 10 (rank : 761)	NC score	0.053111 (rank : 763)
Query Neighborhood Hits	747	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ANKF1_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.127559 (rank : 314)
Query Neighborhood Hits	747	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.206143 (rank : 292)
Query Neighborhood Hits	747	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.256551 (rank : 282)
Query Neighborhood Hits	747	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANPRA_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.050521 (rank : 800)
Query Neighborhood Hits	747	Target Neighborhood Hits	600	Shared Neighborhood Hits	53
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.052118 (rank : 777)
Query Neighborhood Hits	747	Target Neighborhood Hits	646	Shared Neighborhood Hits	54
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.053268 (rank : 761)
Query Neighborhood Hits	747	Target Neighborhood Hits	607	Shared Neighborhood Hits	51
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ARAF_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.052776 (rank : 765)
Query Neighborhood Hits	747	Target Neighborhood Hits	924	Shared Neighborhood Hits	77
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 769)	NC score	0.051813 (rank : 782)
Query Neighborhood Hits	747	Target Neighborhood Hits	874	Shared Neighborhood Hits	65
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ARFG1_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.054118 (rank : 745)
Query Neighborhood Hits	747	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 771)	NC score	0.054590 (rank : 738)
Query Neighborhood Hits	747	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.053976 (rank : 750)
Query Neighborhood Hits	747	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.054285 (rank : 741)
Query Neighborhood Hits	747	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARI1A_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.075053 (rank : 471)
Query Neighborhood Hits	747	Target Neighborhood Hits	787	Shared Neighborhood Hits	169
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI1B_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.055841 (rank : 706)
Query Neighborhood Hits	747	Target Neighborhood Hits	567	Shared Neighborhood Hits	144
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATN1_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.113292 (rank : 330)
Query Neighborhood Hits	747	Target Neighborhood Hits	676	Shared Neighborhood Hits	190
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.058475 (rank : 639)
Query Neighborhood Hits	747	Target Neighborhood Hits	443	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.052664 (rank : 767)
Query Neighborhood Hits	747	Target Neighborhood Hits	445	Shared Neighborhood Hits	108
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AUTS2_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.051056 (rank : 790)
Query Neighborhood Hits	747	Target Neighborhood Hits	342	Shared Neighborhood Hits	96
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAG3_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.050882 (rank : 794)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	86
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 781)	NC score	0.063569 (rank : 546)
Query Neighborhood Hits	747	Target Neighborhood Hits	513	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.099586 (rank : 390)
Query Neighborhood Hits	747	Target Neighborhood Hits	321	Shared Neighborhood Hits	95
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.111195 (rank : 338)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	80
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT4_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.217250 (rank : 288)
Query Neighborhood Hits	747	Target Neighborhood Hits	157	Shared Neighborhood Hits	112
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.249423 (rank : 283)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BCAR1_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.059085 (rank : 624)
Query Neighborhood Hits	747	Target Neighborhood Hits	438	Shared Neighborhood Hits	105
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BLK_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.058514 (rank : 638)
Query Neighborhood Hits	747	Target Neighborhood Hits	994	Shared Neighborhood Hits	94
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.057588 (rank : 658)
Query Neighborhood Hits	747	Target Neighborhood Hits	992	Shared Neighborhood Hits	90
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMX_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.055620 (rank : 714)
Query Neighborhood Hits	747	Target Neighborhood Hits	942	Shared Neighborhood Hits	80
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.055922 (rank : 703)
Query Neighborhood Hits	747	Target Neighborhood Hits	912	Shared Neighborhood Hits	74
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.054083 (rank : 746)
Query Neighborhood Hits	747	Target Neighborhood Hits	883	Shared Neighborhood Hits	68
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRD4_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.052156 (rank : 776)
Query Neighborhood Hits	747	Target Neighborhood Hits	851	Shared Neighborhood Hits	179
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 793)	NC score	0.064248 (rank : 541)
Query Neighborhood Hits	747	Target Neighborhood Hits	845	Shared Neighborhood Hits	178
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTK_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.061204 (rank : 581)
Query Neighborhood Hits	747	Target Neighborhood Hits	1026	Shared Neighborhood Hits	99
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.060755 (rank : 590)
Query Neighborhood Hits	747	Target Neighborhood Hits	1017	Shared Neighborhood Hits	99
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CCNK_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.074225 (rank : 476)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	127
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2AP_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.050531 (rank : 799)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CDN1C_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.071788 (rank : 490)
Query Neighborhood Hits	747	Target Neighborhood Hits	168	Shared Neighborhood Hits	74
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CENA1_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.057944 (rank : 650)
Query Neighborhood Hits	747	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.052962 (rank : 764)
Query Neighborhood Hits	747	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 801)	NC score	0.053964 (rank : 751)
Query Neighborhood Hits	747	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND2_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.056430 (rank : 691)
Query Neighborhood Hits	747	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CITE4_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.062446 (rank : 566)
Query Neighborhood Hits	747	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CJ078_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.098893 (rank : 396)
Query Neighborhood Hits	747	Target Neighborhood Hits	559	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.082376 (rank : 441)
Query Neighborhood Hits	747	Target Neighborhood Hits	408	Shared Neighborhood Hits	99
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.112754 (rank : 331)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.104753 (rank : 362)
Query Neighborhood Hits	747	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.099856 (rank : 388)
Query Neighborhood Hits	747	Target Neighborhood Hits	385	Shared Neighborhood Hits	104
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNOT3_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.062224 (rank : 571)
Query Neighborhood Hits	747	Target Neighborhood Hits	425	Shared Neighborhood Hits	112
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO039_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.056762 (rank : 677)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO1A1_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.059858 (rank : 605)
Query Neighborhood Hits	747	Target Neighborhood Hits	475	Shared Neighborhood Hits	142
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A1_MOUSE
θ value	θ > 10 (rank : 812)	NC score	0.062791 (rank : 558)
Query Neighborhood Hits	747	Target Neighborhood Hits	457	Shared Neighborhood Hits	145
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.062059 (rank : 573)
Query Neighborhood Hits	747	Target Neighborhood Hits	452	Shared Neighborhood Hits	151
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.061319 (rank : 580)
Query Neighborhood Hits	747	Target Neighborhood Hits	466	Shared Neighborhood Hits	150
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A5_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.064143 (rank : 542)
Query Neighborhood Hits	747	Target Neighborhood Hits	383	Shared Neighborhood Hits	125
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO5A1_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.052003 (rank : 779)
Query Neighborhood Hits	747	Target Neighborhood Hits	434	Shared Neighborhood Hits	141
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

COGA1_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.056038 (rank : 700)
Query Neighborhood Hits	747	Target Neighborhood Hits	345	Shared Neighborhood Hits	124
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

COHA1_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.058415 (rank : 642)
Query Neighborhood Hits	747	Target Neighborhood Hits	400	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.055423 (rank : 717)
Query Neighborhood Hits	747	Target Neighborhood Hits	414	Shared Neighborhood Hits	130
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CPSF6_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.103796 (rank : 370)
Query Neighborhood Hits	747	Target Neighborhood Hits	359	Shared Neighborhood Hits	139
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 821)	NC score	0.104910 (rank : 360)
Query Neighborhood Hits	747	Target Neighborhood Hits	356	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRTC1_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.063547 (rank : 547)
Query Neighborhood Hits	747	Target Neighborhood Hits	319	Shared Neighborhood Hits	105
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS007_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.068060 (rank : 520)
Query Neighborhood Hits	747	Target Neighborhood Hits	401	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS016_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.089447 (rank : 415)
Query Neighborhood Hits	747	Target Neighborhood Hits	310	Shared Neighborhood Hits	103
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSK_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.056871 (rank : 675)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	89
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.055704 (rank : 712)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	89
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT032_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.050103 (rank : 805)
Query Neighborhood Hits	747	Target Neighborhood Hits	235	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CU081_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.079898 (rank : 456)
Query Neighborhood Hits	747	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DDR1_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.058888 (rank : 629)
Query Neighborhood Hits	747	Target Neighborhood Hits	819	Shared Neighborhood Hits	65
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.058920 (rank : 628)
Query Neighborhood Hits	747	Target Neighborhood Hits	818	Shared Neighborhood Hits	65
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.057081 (rank : 672)
Query Neighborhood Hits	747	Target Neighborhood Hits	818	Shared Neighborhood Hits	60
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.056337 (rank : 696)
Query Neighborhood Hits	747	Target Neighborhood Hits	813	Shared Neighborhood Hits	60
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DGKK_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.072175 (rank : 487)
Query Neighborhood Hits	747	Target Neighborhood Hits	378	Shared Neighborhood Hits	139
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.057536 (rank : 661)
Query Neighborhood Hits	747	Target Neighborhood Hits	784	Shared Neighborhood Hits	153
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.056513 (rank : 687)
Query Neighborhood Hits	747	Target Neighborhood Hits	839	Shared Neighborhood Hits	142
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DOT1L_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.054775 (rank : 730)
Query Neighborhood Hits	747	Target Neighborhood Hits	660	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EGFR_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.058095 (rank : 646)
Query Neighborhood Hits	747	Target Neighborhood Hits	939	Shared Neighborhood Hits	64
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 838)	NC score	0.057962 (rank : 649)
Query Neighborhood Hits	747	Target Neighborhood Hits	927	Shared Neighborhood Hits	65
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ELN_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.050907 (rank : 793)
Query Neighborhood Hits	747	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ENAH_MOUSE
θ value	θ > 10 (rank : 840)	NC score	0.094998 (rank : 407)
Query Neighborhood Hits	747	Target Neighborhood Hits	919	Shared Neighborhood Hits	211
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENL_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.051001 (rank : 792)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP300_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.076664 (rank : 465)
Query Neighborhood Hits	747	Target Neighborhood Hits	821	Shared Neighborhood Hits	205
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERBB2_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.059722 (rank : 609)
Query Neighborhood Hits	747	Target Neighborhood Hits	918	Shared Neighborhood Hits	72
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.054129 (rank : 744)
Query Neighborhood Hits	747	Target Neighborhood Hits	918	Shared Neighborhood Hits	69
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.053434 (rank : 758)
Query Neighborhood Hits	747	Target Neighborhood Hits	898	Shared Neighborhood Hits	68
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.061103 (rank : 585)
Query Neighborhood Hits	747	Target Neighborhood Hits	910	Shared Neighborhood Hits	72
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FA47A_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.054677 (rank : 733)
Query Neighborhood Hits	747	Target Neighborhood Hits	451	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.052368 (rank : 774)
Query Neighborhood Hits	747	Target Neighborhood Hits	431	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FAK1_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.059395 (rank : 618)
Query Neighborhood Hits	747	Target Neighborhood Hits	850	Shared Neighborhood Hits	66
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.059175 (rank : 622)
Query Neighborhood Hits	747	Target Neighborhood Hits	850	Shared Neighborhood Hits	65
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.060201 (rank : 602)
Query Neighborhood Hits	747	Target Neighborhood Hits	847	Shared Neighborhood Hits	63
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 852)	NC score	0.059794 (rank : 606)
Query Neighborhood Hits	747	Target Neighborhood Hits	851	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FER_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.060309 (rank : 601)
Query Neighborhood Hits	747	Target Neighborhood Hits	1278	Shared Neighborhood Hits	97
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.055613 (rank : 715)
Query Neighborhood Hits	747	Target Neighborhood Hits	978	Shared Neighborhood Hits	75
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 855)	NC score	0.056255 (rank : 697)
Query Neighborhood Hits	747	Target Neighborhood Hits	980	Shared Neighborhood Hits	78
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGR_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.062571 (rank : 564)
Query Neighborhood Hits	747	Target Neighborhood Hits	1067	Shared Neighborhood Hits	110
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 857)	NC score	0.063128 (rank : 552)
Query Neighborhood Hits	747	Target Neighborhood Hits	1069	Shared Neighborhood Hits	105
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FMN2_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.075851 (rank : 467)
Query Neighborhood Hits	747	Target Neighborhood Hits	484	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FMN2_MOUSE
θ value	θ > 10 (rank : 859)	NC score	0.051393 (rank : 787)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.081871 (rank : 445)
Query Neighborhood Hits	747	Target Neighborhood Hits	529	Shared Neighborhood Hits	164
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FRK_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.061362 (rank : 579)
Query Neighborhood Hits	747	Target Neighborhood Hits	1058	Shared Neighborhood Hits	102
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FYN_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.062659 (rank : 560)
Query Neighborhood Hits	747	Target Neighborhood Hits	1078	Shared Neighborhood Hits	111
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.063116 (rank : 553)
Query Neighborhood Hits	747	Target Neighborhood Hits	1073	Shared Neighborhood Hits	109
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GGN_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.086636 (rank : 421)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	112
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.101244 (rank : 382)
Query Neighborhood Hits	747	Target Neighborhood Hits	311	Shared Neighborhood Hits	123
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GSCR1_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.136504 (rank : 307)
Query Neighborhood Hits	747	Target Neighborhood Hits	674	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

GUC2C_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.056412 (rank : 692)
Query Neighborhood Hits	747	Target Neighborhood Hits	624	Shared Neighborhood Hits	58
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2E_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.051433 (rank : 786)
Query Neighborhood Hits	747	Target Neighborhood Hits	692	Shared Neighborhood Hits	57
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.053524 (rank : 754)
Query Neighborhood Hits	747	Target Neighborhood Hits	740	Shared Neighborhood Hits	56
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.058793 (rank : 631)
Query Neighborhood Hits	747	Target Neighborhood Hits	644	Shared Neighborhood Hits	53
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HCK_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.060643 (rank : 594)
Query Neighborhood Hits	747	Target Neighborhood Hits	1035	Shared Neighborhood Hits	104
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.061035 (rank : 586)
Query Neighborhood Hits	747	Target Neighborhood Hits	1029	Shared Neighborhood Hits	102
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HRBL_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.053315 (rank : 760)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	62
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRX_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.070432 (rank : 498)
Query Neighborhood Hits	747	Target Neighborhood Hits	825	Shared Neighborhood Hits	144
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IGF1R_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.055705 (rank : 711)
Query Neighborhood Hits	747	Target Neighborhood Hits	977	Shared Neighborhood Hits	68
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 876)	NC score	0.055897 (rank : 704)
Query Neighborhood Hits	747	Target Neighborhood Hits	973	Shared Neighborhood Hits	67
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.057481 (rank : 663)
Query Neighborhood Hits	747	Target Neighborhood Hits	950	Shared Neighborhood Hits	72
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.057840 (rank : 653)
Query Neighborhood Hits	747	Target Neighborhood Hits	961	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.058131 (rank : 645)
Query Neighborhood Hits	747	Target Neighborhood Hits	963	Shared Neighborhood Hits	69
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 880)	NC score	0.057270 (rank : 667)
Query Neighborhood Hits	747	Target Neighborhood Hits	968	Shared Neighborhood Hits	67
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IRAK1_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.059641 (rank : 611)
Query Neighborhood Hits	747	Target Neighborhood Hits	820	Shared Neighborhood Hits	89
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.054001 (rank : 749)
Query Neighborhood Hits	747	Target Neighborhood Hits	784	Shared Neighborhood Hits	72
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK2_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.057757 (rank : 654)
Query Neighborhood Hits	747	Target Neighborhood Hits	714	Shared Neighborhood Hits	59
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

IRAK3_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.061926 (rank : 576)
Query Neighborhood Hits	747	Target Neighborhood Hits	644	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.060610 (rank : 595)
Query Neighborhood Hits	747	Target Neighborhood Hits	628	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

ITK_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.059497 (rank : 614)
Query Neighborhood Hits	747	Target Neighborhood Hits	1016	Shared Neighborhood Hits	94
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.058976 (rank : 626)
Query Neighborhood Hits	747	Target Neighborhood Hits	985	Shared Neighborhood Hits	91
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAK1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.050294 (rank : 801)
Query Neighborhood Hits	747	Target Neighborhood Hits	858	Shared Neighborhood Hits	62
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.050087 (rank : 806)
Query Neighborhood Hits	747	Target Neighborhood Hits	854	Shared Neighborhood Hits	61
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

K0310_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.060004 (rank : 603)
Query Neighborhood Hits	747	Target Neighborhood Hits	420	Shared Neighborhood Hits	105
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1683_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.052655 (rank : 768)
Query Neighborhood Hits	747	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KIT_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.050581 (rank : 797)
Query Neighborhood Hits	747	Target Neighborhood Hits	953	Shared Neighborhood Hits	62
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.050059 (rank : 807)
Query Neighborhood Hits	747	Target Neighborhood Hits	949	Shared Neighborhood Hits	64
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSYK_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.057037 (rank : 673)
Query Neighborhood Hits	747	Target Neighborhood Hits	901	Shared Neighborhood Hits	72
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 895)	NC score	0.057543 (rank : 660)
Query Neighborhood Hits	747	Target Neighborhood Hits	944	Shared Neighborhood Hits	78
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAD1_HUMAN
θ value	θ > 10 (rank : 896)	NC score	0.060340 (rank : 600)
Query Neighborhood Hits	747	Target Neighborhood Hits	441	Shared Neighborhood Hits	77
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LCK_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.059522 (rank : 613)
Query Neighborhood Hits	747	Target Neighborhood Hits	987	Shared Neighborhood Hits	93
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.059943 (rank : 604)
Query Neighborhood Hits	747	Target Neighborhood Hits	981	Shared Neighborhood Hits	91
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LTK_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.058424 (rank : 641)
Query Neighborhood Hits	747	Target Neighborhood Hits	774	Shared Neighborhood Hits	62
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.057925 (rank : 651)
Query Neighborhood Hits	747	Target Neighborhood Hits	770	Shared Neighborhood Hits	61
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LYN_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.058566 (rank : 636)
Query Neighborhood Hits	747	Target Neighborhood Hits	1022	Shared Neighborhood Hits	99
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.058713 (rank : 634)
Query Neighborhood Hits	747	Target Neighborhood Hits	1023	Shared Neighborhood Hits	102
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K10_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.063850 (rank : 544)
Query Neighborhood Hits	747	Target Neighborhood Hits	1071	Shared Neighborhood Hits	122
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K11_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.071174 (rank : 491)
Query Neighborhood Hits	747	Target Neighborhood Hits	1136	Shared Neighborhood Hits	172
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

M3K12_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.055263 (rank : 721)
Query Neighborhood Hits	747	Target Neighborhood Hits	940	Shared Neighborhood Hits	104
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.054717 (rank : 732)
Query Neighborhood Hits	747	Target Neighborhood Hits	957	Shared Neighborhood Hits	98
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.051054 (rank : 791)
Query Neighborhood Hits	747	Target Neighborhood Hits	911	Shared Neighborhood Hits	66
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.056506 (rank : 688)
Query Neighborhood Hits	747	Target Neighborhood Hits	892	Shared Neighborhood Hits	63
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.056532 (rank : 686)
Query Neighborhood Hits	747	Target Neighborhood Hits	892	Shared Neighborhood Hits	63
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K9_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.062587 (rank : 562)
Query Neighborhood Hits	747	Target Neighborhood Hits	1123	Shared Neighborhood Hits	138
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.062027 (rank : 575)
Query Neighborhood Hits	747	Target Neighborhood Hits	1087	Shared Neighborhood Hits	115
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MADCA_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.064598 (rank : 539)
Query Neighborhood Hits	747	Target Neighborhood Hits	221	Shared Neighborhood Hits	89
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP1A_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.050274 (rank : 802)
Query Neighborhood Hits	747	Target Neighborhood Hits	1626	Shared Neighborhood Hits	177
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP4_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.053461 (rank : 757)
Query Neighborhood Hits	747	Target Neighborhood Hits	428	Shared Neighborhood Hits	89
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.056432 (rank : 690)
Query Neighborhood Hits	747	Target Neighborhood Hits	409	Shared Neighborhood Hits	91
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.085055 (rank : 426)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.083586 (rank : 438)
Query Neighborhood Hits	747	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MATK_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.057280 (rank : 666)
Query Neighborhood Hits	747	Target Neighborhood Hits	954	Shared Neighborhood Hits	80
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.057199 (rank : 670)
Query Neighborhood Hits	747	Target Neighborhood Hits	952	Shared Neighborhood Hits	80
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MBD6_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.124150 (rank : 319)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MERTK_HUMAN
θ value	θ > 10 (rank : 921)	NC score	0.056735 (rank : 681)
Query Neighborhood Hits	747	Target Neighborhood Hits	988	Shared Neighborhood Hits	68
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.056622 (rank : 684)
Query Neighborhood Hits	747	Target Neighborhood Hits	974	Shared Neighborhood Hits	65
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.057545 (rank : 659)
Query Neighborhood Hits	747	Target Neighborhood Hits	831	Shared Neighborhood Hits	62
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.057402 (rank : 664)
Query Neighborhood Hits	747	Target Neighborhood Hits	844	Shared Neighborhood Hits	64
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MILK1_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.061114 (rank : 583)
Query Neighborhood Hits	747	Target Neighborhood Hits	427	Shared Neighborhood Hits	134
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.063028 (rank : 554)
Query Neighborhood Hits	747	Target Neighborhood Hits	1291	Shared Neighborhood Hits	167
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLKL_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.066374 (rank : 531)
Query Neighborhood Hits	747	Target Neighborhood Hits	600	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.059415 (rank : 617)
Query Neighborhood Hits	747	Target Neighborhood Hits	707	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLL4_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.095970 (rank : 402)
Query Neighborhood Hits	747	Target Neighborhood Hits	722	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLTK_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.054947 (rank : 725)
Query Neighborhood Hits	747	Target Neighborhood Hits	911	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.054605 (rank : 736)
Query Neighborhood Hits	747	Target Neighborhood Hits	874	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MNT_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.050162 (rank : 803)
Query Neighborhood Hits	747	Target Neighborhood Hits	496	Shared Neighborhood Hits	110
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MOS_HUMAN
θ value	θ > 10 (rank : 933)	NC score	0.051995 (rank : 780)
Query Neighborhood Hits	747	Target Neighborhood Hits	829	Shared Neighborhood Hits	61
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MUC13_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.080188 (rank : 454)
Query Neighborhood Hits	747	Target Neighborhood Hits	447	Shared Neighborhood Hits	100
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 935)	NC score	0.083677 (rank : 436)
Query Neighborhood Hits	747	Target Neighborhood Hits	388	Shared Neighborhood Hits	76
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 936)	NC score	0.084625 (rank : 430)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	184
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.060749 (rank : 591)
Query Neighborhood Hits	747	Target Neighborhood Hits	1020	Shared Neighborhood Hits	142
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC7_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.133531 (rank : 309)
Query Neighborhood Hits	747	Target Neighborhood Hits	538	Shared Neighborhood Hits	181
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUSK_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.051915 (rank : 781)
Query Neighborhood Hits	747	Target Neighborhood Hits	1074	Shared Neighborhood Hits	63
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 940)	NC score	0.051257 (rank : 788)
Query Neighborhood Hits	747	Target Neighborhood Hits	1057	Shared Neighborhood Hits	62
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

NCOR2_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.070639 (rank : 497)
Query Neighborhood Hits	747	Target Neighborhood Hits	870	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NOLC1_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.084921 (rank : 428)
Query Neighborhood Hits	747	Target Neighborhood Hits	452	Shared Neighborhood Hits	98
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSD1_MOUSE
θ value	θ > 10 (rank : 943)	NC score	0.050020 (rank : 808)
Query Neighborhood Hits	747	Target Neighborhood Hits	472	Shared Neighborhood Hits	80
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NTRK1_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.056048 (rank : 699)
Query Neighborhood Hits	747	Target Neighborhood Hits	1023	Shared Neighborhood Hits	61
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.052776 (rank : 766)
Query Neighborhood Hits	747	Target Neighborhood Hits	1081	Shared Neighborhood Hits	64
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 946)	NC score	0.052647 (rank : 769)
Query Neighborhood Hits	747	Target Neighborhood Hits	1088	Shared Neighborhood Hits	64
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.053117 (rank : 762)
Query Neighborhood Hits	747	Target Neighborhood Hits	1115	Shared Neighborhood Hits	64
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NU214_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.084046 (rank : 433)
Query Neighborhood Hits	747	Target Neighborhood Hits	657	Shared Neighborhood Hits	136
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PCQAP_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.076749 (rank : 464)
Query Neighborhood Hits	747	Target Neighborhood Hits	549	Shared Neighborhood Hits	131
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.055946 (rank : 702)
Query Neighborhood Hits	747	Target Neighborhood Hits	506	Shared Neighborhood Hits	124
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_MOUSE
θ value	θ > 10 (rank : 951)	NC score	0.050814 (rank : 796)
Query Neighborhood Hits	747	Target Neighborhood Hits	275	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDCD7_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.055304 (rank : 719)
Query Neighborhood Hits	747	Target Neighborhood Hits	255	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PELP1_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.069139 (rank : 511)
Query Neighborhood Hits	747	Target Neighborhood Hits	596	Shared Neighborhood Hits	133
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 954)	NC score	0.072539 (rank : 485)
Query Neighborhood Hits	747	Target Neighborhood Hits	709	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PI5PA_MOUSE
θ value	θ > 10 (rank : 955)	NC score	0.068099 (rank : 519)
Query Neighborhood Hits	747	Target Neighborhood Hits	331	Shared Neighborhood Hits	119
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PO121_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.069482 (rank : 508)
Query Neighborhood Hits	747	Target Neighborhood Hits	344	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.067749 (rank : 523)
Query Neighborhood Hits	747	Target Neighborhood Hits	345	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRB3_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.160624 (rank : 302)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	151
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.171741 (rank : 298)
Query Neighborhood Hits	747	Target Neighborhood Hits	330	Shared Neighborhood Hits	162
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.119503 (rank : 326)
Query Neighborhood Hits	747	Target Neighborhood Hits	764	Shared Neighborhood Hits	187
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 961)	NC score	0.102314 (rank : 379)
Query Neighborhood Hits	747	Target Neighborhood Hits	624	Shared Neighborhood Hits	153
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.186293 (rank : 295)
Query Neighborhood Hits	747	Target Neighborhood Hits	385	Shared Neighborhood Hits	179
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 963)	NC score	0.175099 (rank : 297)
Query Neighborhood Hits	747	Target Neighborhood Hits	347	Shared Neighborhood Hits	164
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.104760 (rank : 361)
Query Neighborhood Hits	747	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.087435 (rank : 417)
Query Neighborhood Hits	747	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 966)	NC score	0.090190 (rank : 412)
Query Neighborhood Hits	747	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.138615 (rank : 304)
Query Neighborhood Hits	747	Target Neighborhood Hits	460	Shared Neighborhood Hits	182
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.082650 (rank : 439)
Query Neighborhood Hits	747	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.075122 (rank : 470)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR8_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.068831 (rank : 513)
Query Neighborhood Hits	747	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PTK6_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.059078 (rank : 625)
Query Neighborhood Hits	747	Target Neighborhood Hits	1020	Shared Neighborhood Hits	104
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 972)	NC score	0.059289 (rank : 620)
Query Neighborhood Hits	747	Target Neighborhood Hits	1026	Shared Neighborhood Hits	104
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RAF1_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.054156 (rank : 743)
Query Neighborhood Hits	747	Target Neighborhood Hits	886	Shared Neighborhood Hits	67
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 974)	NC score	0.054047 (rank : 747)
Query Neighborhood Hits	747	Target Neighborhood Hits	886	Shared Neighborhood Hits	66
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAPH1_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.101027 (rank : 383)
Query Neighborhood Hits	747	Target Neighborhood Hits	593	Shared Neighborhood Hits	194
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RERE_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.097058 (rank : 400)
Query Neighborhood Hits	747	Target Neighborhood Hits	779	Shared Neighborhood Hits	204
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 977)	NC score	0.099847 (rank : 389)
Query Neighborhood Hits	747	Target Neighborhood Hits	785	Shared Neighborhood Hits	210
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RET_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.054590 (rank : 737)
Query Neighborhood Hits	747	Target Neighborhood Hits	873	Shared Neighborhood Hits	61
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 979)	NC score	0.054775 (rank : 731)
Query Neighborhood Hits	747	Target Neighborhood Hits	884	Shared Neighborhood Hits	64
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIPK1_HUMAN
θ value	θ > 10 (rank : 980)	NC score	0.052441 (rank : 773)
Query Neighborhood Hits	747	Target Neighborhood Hits	891	Shared Neighborhood Hits	69
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 981)	NC score	0.050574 (rank : 798)
Query Neighborhood Hits	747	Target Neighborhood Hits	874	Shared Neighborhood Hits	67
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 982)	NC score	0.069770 (rank : 504)
Query Neighborhood Hits	747	Target Neighborhood Hits	774	Shared Neighborhood Hits	61
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 983)	NC score	0.064015 (rank : 543)
Query Neighborhood Hits	747	Target Neighborhood Hits	776	Shared Neighborhood Hits	59
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.058714 (rank : 633)
Query Neighborhood Hits	747	Target Neighborhood Hits	828	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RIPK3_MOUSE
θ value	θ > 10 (rank : 985)	NC score	0.058031 (rank : 648)
Query Neighborhood Hits	747	Target Neighborhood Hits	867	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RON_HUMAN
θ value	θ > 10 (rank : 986)	NC score	0.055355 (rank : 718)
Query Neighborhood Hits	747	Target Neighborhood Hits	842	Shared Neighborhood Hits	64
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 987)	NC score	0.055731 (rank : 709)
Query Neighborhood Hits	747	Target Neighborhood Hits	836	Shared Neighborhood Hits	62
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 988)	NC score	0.058071 (rank : 647)
Query Neighborhood Hits	747	Target Neighborhood Hits	1018	Shared Neighborhood Hits	66
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 989)	NC score	0.057847 (rank : 652)
Query Neighborhood Hits	747	Target Neighborhood Hits	1025	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.057698 (rank : 655)
Query Neighborhood Hits	747	Target Neighborhood Hits	1014	Shared Neighborhood Hits	66
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 991)	NC score	0.058729 (rank : 632)
Query Neighborhood Hits	747	Target Neighborhood Hits	1000	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.056593 (rank : 685)
Query Neighborhood Hits	747	Target Neighborhood Hits	907	Shared Neighborhood Hits	64
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RPB1_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.067461 (rank : 525)
Query Neighborhood Hits	747	Target Neighborhood Hits	362	Shared Neighborhood Hits	112
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 994)	NC score	0.067734 (rank : 524)
Query Neighborhood Hits	747	Target Neighborhood Hits	363	Shared Neighborhood Hits	113
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RYK_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.057379 (rank : 665)
Query Neighborhood Hits	747	Target Neighborhood Hits	701	Shared Neighborhood Hits	55
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 996)	NC score	0.056751 (rank : 679)
Query Neighborhood Hits	747	Target Neighborhood Hits	715	Shared Neighborhood Hits	56
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SC24C_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.054549 (rank : 740)
Query Neighborhood Hits	747	Target Neighborhood Hits	662	Shared Neighborhood Hits	130
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELPL_MOUSE
θ value	θ > 10 (rank : 998)	NC score	0.052622 (rank : 770)
Query Neighborhood Hits	747	Target Neighborhood Hits	588	Shared Neighborhood Hits	115
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.061017 (rank : 587)
Query Neighborhood Hits	747	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.100715 (rank : 386)
Query Neighborhood Hits	747	Target Neighborhood Hits	690	Shared Neighborhood Hits	168
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD2_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.053368 (rank : 759)
Query Neighborhood Hits	747	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SF01_HUMAN
θ value	θ > 10 (rank : 1002)	NC score	0.066794 (rank : 530)
Query Neighborhood Hits	747	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 1003)	NC score	0.053466 (rank : 756)
Query Neighborhood Hits	747	Target Neighborhood Hits	240	Shared Neighborhood Hits	93
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 1004)	NC score	0.095965 (rank : 403)
Query Neighborhood Hits	747	Target Neighborhood Hits	263	Shared Neighborhood Hits	117
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.080801 (rank : 451)
Query Neighborhood Hits	747	Target Neighborhood Hits	986	Shared Neighborhood Hits	222
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 1006)	NC score	0.084184 (rank : 432)
Query Neighborhood Hits	747	Target Neighborhood Hits	958	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 1007)	NC score	0.073570 (rank : 479)
Query Neighborhood Hits	747	Target Neighborhood Hits	368	Shared Neighborhood Hits	114
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.061170 (rank : 582)
Query Neighborhood Hits	747	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 1009)	NC score	0.065600 (rank : 535)
Query Neighborhood Hits	747	Target Neighborhood Hits	180	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAP1_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.061874 (rank : 577)
Query Neighborhood Hits	747	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1011)	NC score	0.060730 (rank : 592)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 1012)	NC score	0.060667 (rank : 593)
Query Neighborhood Hits	747	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMR1_MOUSE
θ value	θ > 10 (rank : 1013)	NC score	0.059240 (rank : 621)
Query Neighborhood Hits	747	Target Neighborhood Hits	103	Shared Neighborhood Hits	53
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 1014)	NC score	0.082552 (rank : 440)
Query Neighborhood Hits	747	Target Neighborhood Hits	93	Shared Neighborhood Hits	47
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SPTA3_MOUSE
θ value	θ > 10 (rank : 1015)	NC score	0.055086 (rank : 722)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

SRC_HUMAN
θ value	θ > 10 (rank : 1016)	NC score	0.061111 (rank : 584)
Query Neighborhood Hits	747	Target Neighborhood Hits	1058	Shared Neighborhood Hits	106
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 1017)	NC score	0.060343 (rank : 599)
Query Neighborhood Hits	747	Target Neighborhood Hits	1033	Shared Neighborhood Hits	101
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SREC2_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.053827 (rank : 752)
Query Neighborhood Hits	747	Target Neighborhood Hits	645	Shared Neighborhood Hits	117
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SRMS_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.055728 (rank : 710)
Query Neighborhood Hits	747	Target Neighborhood Hits	946	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.055734 (rank : 708)
Query Neighborhood Hits	747	Target Neighborhood Hits	964	Shared Neighborhood Hits	79
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SRRM1_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.131658 (rank : 311)
Query Neighborhood Hits	747	Target Neighborhood Hits	690	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.122029 (rank : 321)
Query Neighborhood Hits	747	Target Neighborhood Hits	1296	Shared Neighborhood Hits	237
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SSB4_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.052568 (rank : 771)
Query Neighborhood Hits	747	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SYN1_HUMAN
θ value	θ > 10 (rank : 1024)	NC score	0.095765 (rank : 405)
Query Neighborhood Hits	747	Target Neighborhood Hits	419	Shared Neighborhood Hits	191
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.086829 (rank : 419)
Query Neighborhood Hits	747	Target Neighborhood Hits	363	Shared Neighborhood Hits	169
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_HUMAN
θ value	θ > 10 (rank : 1026)	NC score	0.070986 (rank : 493)
Query Neighborhood Hits	747	Target Neighborhood Hits	498	Shared Neighborhood Hits	164
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 1027)	NC score	0.062809 (rank : 557)
Query Neighborhood Hits	747	Target Neighborhood Hits	516	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T22D2_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.066854 (rank : 529)
Query Neighborhood Hits	747	Target Neighborhood Hits	250	Shared Neighborhood Hits	88
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TARA_HUMAN
θ value	θ > 10 (rank : 1029)	NC score	0.075049 (rank : 472)
Query Neighborhood Hits	747	Target Neighborhood Hits	1626	Shared Neighborhood Hits	214
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.103049 (rank : 375)
Query Neighborhood Hits	747	Target Neighborhood Hits	768	Shared Neighborhood Hits	170
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TAU_MOUSE
θ value	θ > 10 (rank : 1031)	NC score	0.067931 (rank : 521)
Query Neighborhood Hits	747	Target Neighborhood Hits	502	Shared Neighborhood Hits	119
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCOF_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.080639 (rank : 452)
Query Neighborhood Hits	747	Target Neighborhood Hits	543	Shared Neighborhood Hits	122
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1033)	NC score	0.087572 (rank : 416)
Query Neighborhood Hits	747	Target Neighborhood Hits	471	Shared Neighborhood Hits	120
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 1034)	NC score	0.054579 (rank : 739)
Query Neighborhood Hits	747	Target Neighborhood Hits	929	Shared Neighborhood Hits	129
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1035)	NC score	0.056028 (rank : 701)
Query Neighborhood Hits	747	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEC_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.060755 (rank : 589)
Query Neighborhood Hits	747	Target Neighborhood Hits	1006	Shared Neighborhood Hits	97
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1037)	NC score	0.059698 (rank : 610)
Query Neighborhood Hits	747	Target Neighborhood Hits	1006	Shared Neighborhood Hits	95
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TIE1_HUMAN
θ value	θ > 10 (rank : 1038)	NC score	0.062934 (rank : 555)
Query Neighborhood Hits	747	Target Neighborhood Hits	1241	Shared Neighborhood Hits	82
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 1039)	NC score	0.063193 (rank : 550)
Query Neighborhood Hits	747	Target Neighborhood Hits	1266	Shared Neighborhood Hits	83
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.062414 (rank : 567)
Query Neighborhood Hits	747	Target Neighborhood Hits	1192	Shared Neighborhood Hits	80
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 1041)	NC score	0.062339 (rank : 569)
Query Neighborhood Hits	747	Target Neighborhood Hits	1204	Shared Neighborhood Hits	78
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TMAP1_HUMAN
θ value	θ > 10 (rank : 1042)	NC score	0.069840 (rank : 501)
Query Neighborhood Hits	747	Target Neighborhood Hits	140	Shared Neighborhood Hits	72
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TNK1_MOUSE
θ value	θ > 10 (rank : 1043)	NC score	0.060449 (rank : 597)
Query Neighborhood Hits	747	Target Neighborhood Hits	806	Shared Neighborhood Hits	65
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TRDN_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.057629 (rank : 657)
Query Neighborhood Hits	747	Target Neighborhood Hits	542	Shared Neighborhood Hits	48
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC4_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.073149 (rank : 483)
Query Neighborhood Hits	747	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	θ > 10 (rank : 1046)	NC score	0.073191 (rank : 482)
Query Neighborhood Hits	747	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.077124 (rank : 463)
Query Neighborhood Hits	747	Target Neighborhood Hits	122	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.078619 (rank : 459)
Query Neighborhood Hits	747	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPV3_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.219867 (rank : 287)
Query Neighborhood Hits	747	Target Neighborhood Hits	198	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.216930 (rank : 289)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	133
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.114272 (rank : 328)
Query Neighborhood Hits	747	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.104995 (rank : 356)
Query Neighborhood Hits	747	Target Neighborhood Hits	117	Shared Neighborhood Hits	79
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TXK_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.062054 (rank : 574)
Query Neighborhood Hits	747	Target Neighborhood Hits	971	Shared Neighborhood Hits	90
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.062225 (rank : 570)
Query Neighborhood Hits	747	Target Neighborhood Hits	980	Shared Neighborhood Hits	94
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TYRO3_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.055863 (rank : 705)
Query Neighborhood Hits	747	Target Neighborhood Hits	995	Shared Neighborhood Hits	63
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.056129 (rank : 698)
Query Neighborhood Hits	747	Target Neighborhood Hits	1007	Shared Neighborhood Hits	64
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UFO_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.056382 (rank : 694)
Query Neighborhood Hits	747	Target Neighborhood Hits	981	Shared Neighborhood Hits	70
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 1058)	NC score	0.056387 (rank : 693)
Query Neighborhood Hits	747	Target Neighborhood Hits	988	Shared Neighborhood Hits	65
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

VASP_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.056738 (rank : 680)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	97
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_MOUSE
θ value	θ > 10 (rank : 1060)	NC score	0.059340 (rank : 619)
Query Neighborhood Hits	747	Target Neighborhood Hits	195	Shared Neighborhood Hits	76
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VCX3_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.053759 (rank : 753)
Query Neighborhood Hits	747	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

WASF1_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.062087 (rank : 572)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	115
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.063379 (rank : 548)
Query Neighborhood Hits	747	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.062915 (rank : 556)
Query Neighborhood Hits	747	Target Neighborhood Hits	280	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 1065)	NC score	0.078934 (rank : 457)
Query Neighborhood Hits	747	Target Neighborhood Hits	315	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.051752 (rank : 783)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF3_MOUSE
θ value	θ > 10 (rank : 1067)	NC score	0.054210 (rank : 742)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WASF4_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.061508 (rank : 578)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.164056 (rank : 300)
Query Neighborhood Hits	747	Target Neighborhood Hits	458	Shared Neighborhood Hits	192
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.144253 (rank : 303)
Query Neighborhood Hits	747	Target Neighborhood Hits	392	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.084856 (rank : 429)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	145
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.086270 (rank : 423)
Query Neighborhood Hits	747	Target Neighborhood Hits	339	Shared Neighborhood Hits	148
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.058847 (rank : 630)
Query Neighborhood Hits	747	Target Neighborhood Hits	195	Shared Neighborhood Hits	98
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.080178 (rank : 455)
Query Neighborhood Hits	747	Target Neighborhood Hits	223	Shared Neighborhood Hits	107
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.107163 (rank : 346)
Query Neighborhood Hits	747	Target Neighborhood Hits	354	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 1076)	NC score	0.109364 (rank : 340)
Query Neighborhood Hits	747	Target Neighborhood Hits	362	Shared Neighborhood Hits	137
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.058941 (rank : 627)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.120483 (rank : 323)
Query Neighborhood Hits	747	Target Neighborhood Hits	329	Shared Neighborhood Hits	146
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.124383 (rank : 316)
Query Neighborhood Hits	747	Target Neighborhood Hits	310	Shared Neighborhood Hits	140
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WNK2_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.065777 (rank : 534)
Query Neighborhood Hits	747	Target Neighborhood Hits	1407	Shared Neighborhood Hits	238
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK4_HUMAN
θ value	θ > 10 (rank : 1081)	NC score	0.054003 (rank : 748)
Query Neighborhood Hits	747	Target Neighborhood Hits	1043	Shared Neighborhood Hits	174
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YES_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.062686 (rank : 559)
Query Neighborhood Hits	747	Target Neighborhood Hits	1059	Shared Neighborhood Hits	106
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1083)	NC score	0.062481 (rank : 565)
Query Neighborhood Hits	747	Target Neighborhood Hits	1052	Shared Neighborhood Hits	103
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YLPM1_MOUSE
θ value	θ > 10 (rank : 1084)	NC score	0.106990 (rank : 349)
Query Neighborhood Hits	747	Target Neighborhood Hits	505	Shared Neighborhood Hits	157
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZAP70_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.060405 (rank : 598)
Query Neighborhood Hits	747	Target Neighborhood Hits	893	Shared Neighborhood Hits	74
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.059485 (rank : 615)
Query Neighborhood Hits	747	Target Neighborhood Hits	905	Shared Neighborhood Hits	73
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZN207_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.086111 (rank : 424)
Query Neighborhood Hits	747	Target Neighborhood Hits	326	Shared Neighborhood Hits	91
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

CSKI2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	747	Target Neighborhood Hits	747	Shared Neighborhood Hits	747
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
NC score	0.976540 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	747	Target Neighborhood Hits	812	Shared Neighborhood Hits	539
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI1_HUMAN
NC score	0.947646 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	747	Target Neighborhood Hits	997	Shared Neighborhood Hits	529
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
NC score	0.942212 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	747	Target Neighborhood Hits	1031	Shared Neighborhood Hits	520
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANKS1_HUMAN
NC score	0.895314 (rank : 5)	θ value	7.75577e-52 (rank : 5)
Query Neighborhood Hits	747	Target Neighborhood Hits	438	Shared Neighborhood Hits	356
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
NC score	0.890022 (rank : 6)	θ value	8.02596e-49 (rank : 6)
Query Neighborhood Hits	747	Target Neighborhood Hits	453	Shared Neighborhood Hits	360
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR29_HUMAN
NC score	0.877292 (rank : 7)	θ value	4.15078e-21 (rank : 28)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.872627 (rank : 8)	θ value	3.28887e-18 (rank : 42)
Query Neighborhood Hits	747	Target Neighborhood Hits	301	Shared Neighborhood Hits	289
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.870954 (rank : 9)	θ value	1.24977e-17 (rank : 49)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	288
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.869086 (rank : 10)	θ value	4.9032e-22 (rank : 23)
Query Neighborhood Hits	747	Target Neighborhood Hits	439	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR16_HUMAN
NC score	0.867334 (rank : 11)	θ value	1.29331e-14 (rank : 71)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	282
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR42_HUMAN
NC score	0.867027 (rank : 12)	θ value	3.17815e-21 (rank : 27)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	278
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

TNKS1_HUMAN
NC score	0.864838 (rank : 13)	θ value	7.56453e-23 (rank : 20)
Query Neighborhood Hits	747	Target Neighborhood Hits	477	Shared Neighborhood Hits	373
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR50_HUMAN
NC score	0.864769 (rank : 14)	θ value	5.79196e-23 (rank : 19)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	306
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR42_MOUSE
NC score	0.863198 (rank : 15)	θ value	2.69047e-20 (rank : 33)
Query Neighborhood Hits	747	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB7_HUMAN
NC score	0.861779 (rank : 16)	θ value	1.92812e-18 (rank : 39)
Query Neighborhood Hits	747	Target Neighborhood Hits	296	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
NC score	0.861729 (rank : 17)	θ value	2.5182e-18 (rank : 40)
Query Neighborhood Hits	747	Target Neighborhood Hits	296	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB10_MOUSE
NC score	0.860107 (rank : 18)	θ value	4.58923e-20 (rank : 35)
Query Neighborhood Hits	747	Target Neighborhood Hits	301	Shared Neighborhood Hits	286
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB3_MOUSE
NC score	0.859941 (rank : 19)	θ value	9.56915e-18 (rank : 47)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB10_HUMAN
NC score	0.859292 (rank : 20)	θ value	5.60996e-18 (rank : 44)
Query Neighborhood Hits	747	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB3_HUMAN
NC score	0.858444 (rank : 21)	θ value	8.65492e-19 (rank : 38)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR28_MOUSE
NC score	0.855647 (rank : 22)	θ value	3.28125e-26 (rank : 11)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	296
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR44_HUMAN
NC score	0.855626 (rank : 23)	θ value	9.87957e-23 (rank : 21)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	300
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

TNKS2_HUMAN
NC score	0.855599 (rank : 24)	θ value	4.43474e-23 (rank : 18)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR28_HUMAN
NC score	0.853867 (rank : 25)	θ value	3.07116e-24 (rank : 14)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK1_HUMAN
NC score	0.852899 (rank : 26)	θ value	5.97985e-28 (rank : 9)
Query Neighborhood Hits	747	Target Neighborhood Hits	416	Shared Neighborhood Hits	306
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.852171 (rank : 27)	θ value	3.50572e-28 (rank : 8)
Query Neighborhood Hits	747	Target Neighborhood Hits	430	Shared Neighborhood Hits	307
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

INVS_HUMAN
NC score	0.850711 (rank : 28)	θ value	4.29542e-18 (rank : 43)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	312
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANR52_MOUSE
NC score	0.849052 (rank : 29)	θ value	1.99067e-23 (rank : 17)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.848754 (rank : 30)	θ value	1.5242e-23 (rank : 16)
Query Neighborhood Hits	747	Target Neighborhood Hits	322	Shared Neighborhood Hits	298
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

FANK1_HUMAN
NC score	0.848654 (rank : 31)	θ value	8.38298e-14 (rank : 81)
Query Neighborhood Hits	747	Target Neighborhood Hits	326	Shared Neighborhood Hits	292
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
NC score	0.847461 (rank : 32)	θ value	4.59992e-12 (rank : 97)
Query Neighborhood Hits	747	Target Neighborhood Hits	325	Shared Neighborhood Hits	291
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

INVS_MOUSE
NC score	0.847019 (rank : 33)	θ value	5.60996e-18 (rank : 45)
Query Neighborhood Hits	747	Target Neighborhood Hits	609	Shared Neighborhood Hits	346
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB13_MOUSE
NC score	0.846584 (rank : 34)	θ value	8.95645e-16 (rank : 62)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.846441 (rank : 35)	θ value	1.52774e-15 (rank : 64)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANK3_HUMAN
NC score	0.843506 (rank : 36)	θ value	1.73987e-27 (rank : 10)
Query Neighborhood Hits	747	Target Neighborhood Hits	853	Shared Neighborhood Hits	345
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANKR2_MOUSE
NC score	0.842960 (rank : 37)	θ value	5.8054e-15 (rank : 69)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	290
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR39_MOUSE
NC score	0.842733 (rank : 38)	θ value	1.33837e-11 (rank : 102)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_HUMAN
NC score	0.842674 (rank : 39)	θ value	3.89403e-11 (rank : 108)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB2_HUMAN
NC score	0.842379 (rank : 40)	θ value	6.62687e-19 (rank : 37)
Query Neighborhood Hits	747	Target Neighborhood Hits	309	Shared Neighborhood Hits	288
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR23_MOUSE
NC score	0.841163 (rank : 41)	θ value	6.41864e-14 (rank : 78)
Query Neighborhood Hits	747	Target Neighborhood Hits	296	Shared Neighborhood Hits	289
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANKR2_HUMAN
NC score	0.841085 (rank : 42)	θ value	2.60593e-15 (rank : 66)
Query Neighborhood Hits	747	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB2_MOUSE
NC score	0.837571 (rank : 43)	θ value	4.02038e-16 (rank : 59)
Query Neighborhood Hits	747	Target Neighborhood Hits	321	Shared Neighborhood Hits	289
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR23_HUMAN
NC score	0.835743 (rank : 44)	θ value	6.00763e-12 (rank : 101)
Query Neighborhood Hits	747	Target Neighborhood Hits	291	Shared Neighborhood Hits	286
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

MYPT1_MOUSE
NC score	0.834106 (rank : 45)	θ value	1.24977e-17 (rank : 48)
Query Neighborhood Hits	747	Target Neighborhood Hits	539	Shared Neighborhood Hits	308
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANKS6_HUMAN
NC score	0.832563 (rank : 46)	θ value	8.38298e-14 (rank : 80)
Query Neighborhood Hits	747	Target Neighborhood Hits	411	Shared Neighborhood Hits	326
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

TRPA1_MOUSE
NC score	0.832363 (rank : 47)	θ value	1.99529e-15 (rank : 65)
Query Neighborhood Hits	747	Target Neighborhood Hits	343	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.832325 (rank : 48)	θ value	4.02038e-16 (rank : 60)
Query Neighborhood Hits	747	Target Neighborhood Hits	339	Shared Neighborhood Hits	293
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANKR1_HUMAN
NC score	0.832017 (rank : 49)	θ value	2.98157e-11 (rank : 104)
Query Neighborhood Hits	747	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKS6_MOUSE
NC score	0.831910 (rank : 50)	θ value	4.16044e-13 (rank : 85)
Query Neighborhood Hits	747	Target Neighborhood Hits	435	Shared Neighborhood Hits	331
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKR1_MOUSE
NC score	0.831581 (rank : 51)	θ value	2.98157e-11 (rank : 105)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	289
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

GABP2_MOUSE
NC score	0.830167 (rank : 52)	θ value	2.0648e-12 (rank : 91)
Query Neighborhood Hits	747	Target Neighborhood Hits	429	Shared Neighborhood Hits	297
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR49_MOUSE
NC score	0.829815 (rank : 53)	θ value	3.29651e-10 (rank : 119)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

CDN2C_HUMAN
NC score	0.829593 (rank : 54)	θ value	1.133e-10 (rank : 112)
Query Neighborhood Hits	747	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_MOUSE
NC score	0.828994 (rank : 55)	θ value	3.29651e-10 (rank : 120)
Query Neighborhood Hits	747	Target Neighborhood Hits	270	Shared Neighborhood Hits	268
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

GABP3_MOUSE
NC score	0.828525 (rank : 56)	θ value	2.69671e-12 (rank : 93)
Query Neighborhood Hits	747	Target Neighborhood Hits	330	Shared Neighborhood Hits	278
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

PP16A_MOUSE
NC score	0.828496 (rank : 57)	θ value	8.10077e-17 (rank : 55)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	287
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

GABP2_HUMAN
NC score	0.827899 (rank : 58)	θ value	7.09661e-13 (rank : 88)
Query Neighborhood Hits	747	Target Neighborhood Hits	454	Shared Neighborhood Hits	296
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANR49_HUMAN
NC score	0.825463 (rank : 59)	θ value	5.62301e-10 (rank : 122)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

BCL3_HUMAN
NC score	0.824887 (rank : 60)	θ value	4.59992e-12 (rank : 96)
Query Neighborhood Hits	747	Target Neighborhood Hits	324	Shared Neighborhood Hits	292
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

PA2G6_MOUSE
NC score	0.823259 (rank : 61)	θ value	2.20605e-14 (rank : 74)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB8_MOUSE
NC score	0.823010 (rank : 62)	θ value	4.76016e-09 (rank : 139)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_HUMAN
NC score	0.822394 (rank : 63)	θ value	4.76016e-09 (rank : 138)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PP16B_HUMAN
NC score	0.821594 (rank : 64)	θ value	6.85773e-16 (rank : 61)
Query Neighborhood Hits	747	Target Neighborhood Hits	307	Shared Neighborhood Hits	282
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

MYPT2_HUMAN
NC score	0.821399 (rank : 65)	θ value	1.86321e-21 (rank : 26)
Query Neighborhood Hits	747	Target Neighborhood Hits	707	Shared Neighborhood Hits	311
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PP16A_HUMAN
NC score	0.821357 (rank : 66)	θ value	4.91457e-14 (rank : 77)
Query Neighborhood Hits	747	Target Neighborhood Hits	340	Shared Neighborhood Hits	283
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

BCL3_MOUSE
NC score	0.821341 (rank : 67)	θ value	2.98157e-11 (rank : 107)
Query Neighborhood Hits	747	Target Neighborhood Hits	388	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

MIB1_HUMAN
NC score	0.821255 (rank : 68)	θ value	5.42112e-21 (rank : 29)
Query Neighborhood Hits	747	Target Neighborhood Hits	470	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.820794 (rank : 69)	θ value	5.42112e-21 (rank : 30)
Query Neighborhood Hits	747	Target Neighborhood Hits	471	Shared Neighborhood Hits	300
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ASB16_MOUSE
NC score	0.820430 (rank : 70)	θ value	3.89403e-11 (rank : 109)
Query Neighborhood Hits	747	Target Neighborhood Hits	306	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB9_HUMAN
NC score	0.820198 (rank : 71)	θ value	3.76295e-14 (rank : 75)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	257
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

PP16B_MOUSE
NC score	0.819414 (rank : 72)	θ value	1.29331e-14 (rank : 72)
Query Neighborhood Hits	747	Target Neighborhood Hits	302	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ASB5_HUMAN
NC score	0.817920 (rank : 73)	θ value	4.74913e-17 (rank : 53)
Query Neighborhood Hits	747	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
NC score	0.815945 (rank : 74)	θ value	4.74913e-17 (rank : 54)
Query Neighborhood Hits	747	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB15_HUMAN
NC score	0.814905 (rank : 75)	θ value	3.18553e-13 (rank : 84)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MYPT1_HUMAN
NC score	0.814529 (rank : 76)	θ value	7.32683e-18 (rank : 46)
Query Neighborhood Hits	747	Target Neighborhood Hits	723	Shared Neighborhood Hits	311
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANKS3_MOUSE
NC score	0.813038 (rank : 77)	θ value	5.62301e-10 (rank : 121)
Query Neighborhood Hits	747	Target Neighborhood Hits	355	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB11_HUMAN
NC score	0.812978 (rank : 78)	θ value	5.43371e-13 (rank : 87)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MIB2_MOUSE
NC score	0.812439 (rank : 79)	θ value	2.7842e-17 (rank : 51)
Query Neighborhood Hits	747	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MIB2_HUMAN
NC score	0.811776 (rank : 80)	θ value	3.28887e-18 (rank : 41)
Query Neighborhood Hits	747	Target Neighborhood Hits	438	Shared Neighborhood Hits	294
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB9_MOUSE
NC score	0.811449 (rank : 81)	θ value	3.40345e-15 (rank : 68)
Query Neighborhood Hits	747	Target Neighborhood Hits	257	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CDN2D_HUMAN
NC score	0.810973 (rank : 82)	θ value	1.99992e-07 (rank : 162)
Query Neighborhood Hits	747	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANKS3_HUMAN
NC score	0.810283 (rank : 83)	θ value	2.52405e-10 (rank : 115)
Query Neighborhood Hits	747	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB16_HUMAN
NC score	0.810224 (rank : 84)	θ value	8.97725e-08 (rank : 159)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB11_MOUSE
NC score	0.810112 (rank : 85)	θ value	2.69671e-12 (rank : 92)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKR5_MOUSE
NC score	0.808046 (rank : 86)	θ value	4.76016e-09 (rank : 137)
Query Neighborhood Hits	747	Target Neighborhood Hits	298	Shared Neighborhood Hits	286
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANK2_HUMAN
NC score	0.807064 (rank : 87)	θ value	4.28545e-26 (rank : 12)
Query Neighborhood Hits	747	Target Neighborhood Hits	1615	Shared Neighborhood Hits	462
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB15_MOUSE
NC score	0.807047 (rank : 88)	θ value	3.52202e-12 (rank : 95)
Query Neighborhood Hits	747	Target Neighborhood Hits	292	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKR5_HUMAN
NC score	0.804657 (rank : 89)	θ value	1.38499e-08 (rank : 146)
Query Neighborhood Hits	747	Target Neighborhood Hits	297	Shared Neighborhood Hits	284
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB14_MOUSE
NC score	0.804070 (rank : 90)	θ value	1.133e-10 (rank : 111)
Query Neighborhood Hits	747	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASZ1_HUMAN
NC score	0.803468 (rank : 91)	θ value	2.79066e-09 (rank : 135)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CDN2D_MOUSE
NC score	0.802480 (rank : 92)	θ value	1.99992e-07 (rank : 163)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	265
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR10_HUMAN
NC score	0.801641 (rank : 93)	θ value	3.29651e-10 (rank : 118)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

MTPN_MOUSE
NC score	0.801581 (rank : 94)	θ value	2.44474e-05 (rank : 227)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANR10_MOUSE
NC score	0.801082 (rank : 95)	θ value	3.08544e-08 (rank : 150)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

PA2G6_HUMAN
NC score	0.800963 (rank : 96)	θ value	4.45536e-07 (rank : 174)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

IKBA_HUMAN
NC score	0.799342 (rank : 97)	θ value	5.62301e-10 (rank : 124)
Query Neighborhood Hits	747	Target Neighborhood Hits	280	Shared Neighborhood Hits	272
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASZ1_MOUSE
NC score	0.798599 (rank : 98)	θ value	3.08544e-08 (rank : 151)
Query Neighborhood Hits	747	Target Neighborhood Hits	319	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MTPN_HUMAN
NC score	0.798083 (rank : 99)	θ value	2.44474e-05 (rank : 226)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

EHMT1_HUMAN
NC score	0.797949 (rank : 100)	θ value	2.35696e-16 (rank : 57)
Query Neighborhood Hits	747	Target Neighborhood Hits	417	Shared Neighborhood Hits	312
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB4_HUMAN
NC score	0.797860 (rank : 101)	θ value	1.74796e-11 (rank : 103)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CT086_HUMAN
NC score	0.797263 (rank : 102)	θ value	0.00020696 (rank : 253)
Query Neighborhood Hits	747	Target Neighborhood Hits	277	Shared Neighborhood Hits	273
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANRA2_HUMAN
NC score	0.796984 (rank : 103)	θ value	1.38499e-08 (rank : 147)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	278
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB4_MOUSE
NC score	0.796518 (rank : 104)	θ value	2.98157e-11 (rank : 106)
Query Neighborhood Hits	747	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANRA2_MOUSE
NC score	0.793428 (rank : 105)	θ value	4.0297e-08 (rank : 155)
Query Neighborhood Hits	747	Target Neighborhood Hits	287	Shared Neighborhood Hits	277
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR22_HUMAN
NC score	0.790239 (rank : 106)	θ value	1.80886e-08 (rank : 149)
Query Neighborhood Hits	747	Target Neighborhood Hits	243	Shared Neighborhood Hits	241
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANKR7_HUMAN
NC score	0.790122 (rank : 107)	θ value	3.64472e-09 (rank : 136)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	276
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

IKBA_MOUSE
NC score	0.788148 (rank : 108)	θ value	9.59137e-10 (rank : 128)
Query Neighborhood Hits	747	Target Neighborhood Hits	283	Shared Neighborhood Hits	273
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IKBE_MOUSE
NC score	0.787647 (rank : 109)	θ value	2.52405e-10 (rank : 117)
Query Neighborhood Hits	747	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ASB12_MOUSE
NC score	0.787146 (rank : 110)	θ value	1.06045e-08 (rank : 145)
Query Neighborhood Hits	747	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

RN5A_HUMAN
NC score	0.786499 (rank : 111)	θ value	1.9326e-10 (rank : 114)
Query Neighborhood Hits	747	Target Neighborhood Hits	608	Shared Neighborhood Hits	300
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RFXK_HUMAN
NC score	0.786261 (rank : 112)	θ value	2.88788e-06 (rank : 194)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	268
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

BARD1_HUMAN
NC score	0.785847 (rank : 113)	θ value	5.62301e-10 (rank : 123)
Query Neighborhood Hits	747	Target Neighborhood Hits	427	Shared Neighborhood Hits	291
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR46_HUMAN
NC score	0.785738 (rank : 114)	θ value	0.000158464 (rank : 251)
Query Neighborhood Hits	747	Target Neighborhood Hits	281	Shared Neighborhood Hits	279
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

BARD1_MOUSE
NC score	0.784527 (rank : 115)	θ value	7.34386e-10 (rank : 126)
Query Neighborhood Hits	747	Target Neighborhood Hits	411	Shared Neighborhood Hits	286
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

EHMT2_HUMAN
NC score	0.784098 (rank : 116)	θ value	4.91457e-14 (rank : 76)
Query Neighborhood Hits	747	Target Neighborhood Hits	498	Shared Neighborhood Hits	316
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB12_HUMAN
NC score	0.780868 (rank : 117)	θ value	0.000121331 (rank : 247)
Query Neighborhood Hits	747	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR46_MOUSE
NC score	0.780199 (rank : 118)	θ value	0.000461057 (rank : 268)
Query Neighborhood Hits	747	Target Neighborhood Hits	274	Shared Neighborhood Hits	272
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

EHMT2_MOUSE
NC score	0.777518 (rank : 119)	θ value	1.09485e-13 (rank : 82)
Query Neighborhood Hits	747	Target Neighborhood Hits	750	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB1_MOUSE
NC score	0.776683 (rank : 120)	θ value	9.92553e-07 (rank : 178)
Query Neighborhood Hits	747	Target Neighborhood Hits	292	Shared Neighborhood Hits	275
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_HUMAN
NC score	0.775683 (rank : 121)	θ value	1.87187e-05 (rank : 220)
Query Neighborhood Hits	747	Target Neighborhood Hits	291	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR35_HUMAN
NC score	0.774870 (rank : 122)	θ value	1.80466e-16 (rank : 56)
Query Neighborhood Hits	747	Target Neighborhood Hits	784	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ACBD6_MOUSE
NC score	0.773546 (rank : 123)	θ value	3.41135e-07 (rank : 168)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	288
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

AN36B_HUMAN
NC score	0.773419 (rank : 124)	θ value	1.06045e-08 (rank : 144)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	283
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR32_HUMAN
NC score	0.771532 (rank : 125)	θ value	2.13673e-09 (rank : 132)
Query Neighborhood Hits	747	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBE_HUMAN
NC score	0.769992 (rank : 126)	θ value	2.52405e-10 (rank : 116)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ACBD6_HUMAN
NC score	0.767093 (rank : 127)	θ value	4.45536e-07 (rank : 171)
Query Neighborhood Hits	747	Target Neighborhood Hits	304	Shared Neighborhood Hits	286
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

RFXK_MOUSE
NC score	0.766998 (rank : 128)	θ value	0.00869519 (rank : 312)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

IKBB_MOUSE
NC score	0.762093 (rank : 129)	θ value	4.45536e-07 (rank : 172)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

USH1G_HUMAN
NC score	0.760914 (rank : 130)	θ value	6.21693e-09 (rank : 141)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
NC score	0.760704 (rank : 131)	θ value	6.21693e-09 (rank : 142)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR32_MOUSE
NC score	0.759213 (rank : 132)	θ value	6.87365e-08 (rank : 157)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBB_HUMAN
NC score	0.756834 (rank : 133)	θ value	0.000121331 (rank : 249)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ZDH17_HUMAN
NC score	0.752832 (rank : 134)	θ value	2.13179e-17 (rank : 50)
Query Neighborhood Hits	747	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR11_HUMAN
NC score	0.751809 (rank : 135)	θ value	2.20605e-14 (rank : 73)
Query Neighborhood Hits	747	Target Neighborhood Hits	1289	Shared Neighborhood Hits	388
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANS4B_HUMAN
NC score	0.751424 (rank : 136)	θ value	2.61198e-07 (rank : 166)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH17_MOUSE
NC score	0.748490 (rank : 137)	θ value	3.63628e-17 (rank : 52)
Query Neighborhood Hits	747	Target Neighborhood Hits	328	Shared Neighborhood Hits	277
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANFY1_MOUSE
NC score	0.747653 (rank : 138)	θ value	2.43908e-13 (rank : 83)
Query Neighborhood Hits	747	Target Neighborhood Hits	480	Shared Neighborhood Hits	295
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

POTE8_HUMAN
NC score	0.746410 (rank : 139)	θ value	3.08544e-08 (rank : 153)
Query Neighborhood Hits	747	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

CTTB2_HUMAN
NC score	0.746272 (rank : 140)	θ value	3.51386e-20 (rank : 34)
Query Neighborhood Hits	747	Target Neighborhood Hits	1061	Shared Neighborhood Hits	350
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANFY1_HUMAN
NC score	0.746187 (rank : 141)	θ value	5.43371e-13 (rank : 86)
Query Neighborhood Hits	747	Target Neighborhood Hits	480	Shared Neighborhood Hits	289
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

SHAN1_HUMAN
NC score	0.745246 (rank : 142)	θ value	4.59992e-12 (rank : 100)
Query Neighborhood Hits	747	Target Neighborhood Hits	1041	Shared Neighborhood Hits	486
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

RN5A_MOUSE
NC score	0.743854 (rank : 143)	θ value	9.26847e-13 (rank : 89)
Query Neighborhood Hits	747	Target Neighborhood Hits	899	Shared Neighborhood Hits	324
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR19_HUMAN
NC score	0.741355 (rank : 144)	θ value	1.63604e-09 (rank : 130)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	271
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR41_HUMAN
NC score	0.740179 (rank : 145)	θ value	0.000270298 (rank : 257)
Query Neighborhood Hits	747	Target Neighborhood Hits	332	Shared Neighborhood Hits	268
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ZDH13_MOUSE
NC score	0.738488 (rank : 146)	θ value	6.41864e-14 (rank : 79)
Query Neighborhood Hits	747	Target Neighborhood Hits	329	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANS4B_MOUSE
NC score	0.738486 (rank : 147)	θ value	1.69304e-06 (rank : 187)
Query Neighborhood Hits	747	Target Neighborhood Hits	294	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH13_HUMAN
NC score	0.736274 (rank : 148)	θ value	9.26847e-13 (rank : 90)
Query Neighborhood Hits	747	Target Neighborhood Hits	322	Shared Neighborhood Hits	276
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

AN36A_HUMAN
NC score	0.730513 (rank : 149)	θ value	0.000461057 (rank : 266)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	265
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR37_HUMAN
NC score	0.729262 (rank : 150)	θ value	5.44631e-05 (rank : 236)
Query Neighborhood Hits	747	Target Neighborhood Hits	247	Shared Neighborhood Hits	245
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANKY2_HUMAN
NC score	0.727945 (rank : 151)	θ value	1.69304e-06 (rank : 186)
Query Neighborhood Hits	747	Target Neighborhood Hits	306	Shared Neighborhood Hits	260
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

SNCAP_HUMAN
NC score	0.717207 (rank : 152)	θ value	2.21117e-06 (rank : 191)
Query Neighborhood Hits	747	Target Neighborhood Hits	313	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR37_MOUSE
NC score	0.716174 (rank : 153)	θ value	1.87187e-05 (rank : 219)
Query Neighborhood Hits	747	Target Neighborhood Hits	237	Shared Neighborhood Hits	235
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR15_HUMAN
NC score	0.715593 (rank : 154)	θ value	4.0297e-08 (rank : 154)
Query Neighborhood Hits	747	Target Neighborhood Hits	478	Shared Neighborhood Hits	277
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR12_HUMAN
NC score	0.712698 (rank : 155)	θ value	9.90251e-15 (rank : 70)
Query Neighborhood Hits	747	Target Neighborhood Hits	1081	Shared Neighborhood Hits	319
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR47_MOUSE
NC score	0.711753 (rank : 156)	θ value	2.61198e-07 (rank : 165)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	268
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANKY2_MOUSE
NC score	0.705989 (rank : 157)	θ value	2.88788e-06 (rank : 192)
Query Neighborhood Hits	747	Target Neighborhood Hits	316	Shared Neighborhood Hits	263
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

BCOR_MOUSE
NC score	0.705316 (rank : 158)	θ value	3.41135e-07 (rank : 170)
Query Neighborhood Hits	747	Target Neighborhood Hits	521	Shared Neighborhood Hits	310
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR21_HUMAN
NC score	0.701328 (rank : 159)	θ value	1.80886e-08 (rank : 148)
Query Neighborhood Hits	747	Target Neighborhood Hits	864	Shared Neighborhood Hits	310
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.700501 (rank : 160)	θ value	8.11959e-09 (rank : 143)
Query Neighborhood Hits	747	Target Neighborhood Hits	893	Shared Neighborhood Hits	313
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NFKB1_HUMAN
NC score	0.699985 (rank : 161)	θ value	6.87365e-08 (rank : 158)
Query Neighborhood Hits	747	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

KRIT1_MOUSE
NC score	0.699562 (rank : 162)	θ value	5.62301e-10 (rank : 125)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	228
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NFKB1_MOUSE
NC score	0.699422 (rank : 163)	θ value	8.97725e-08 (rank : 160)
Query Neighborhood Hits	747	Target Neighborhood Hits	300	Shared Neighborhood Hits	273
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

BCOR_HUMAN
NC score	0.697604 (rank : 164)	θ value	3.41135e-07 (rank : 169)
Query Neighborhood Hits	747	Target Neighborhood Hits	609	Shared Neighborhood Hits	321
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

NFKB2_HUMAN
NC score	0.692577 (rank : 165)	θ value	9.92553e-07 (rank : 182)
Query Neighborhood Hits	747	Target Neighborhood Hits	325	Shared Neighborhood Hits	283
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

KRIT1_HUMAN
NC score	0.689862 (rank : 166)	θ value	3.08544e-08 (rank : 152)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	220
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR47_HUMAN
NC score	0.689681 (rank : 167)	θ value	4.92598e-06 (rank : 200)
Query Neighborhood Hits	747	Target Neighborhood Hits	369	Shared Neighborhood Hits	273
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB6_HUMAN
NC score	0.686233 (rank : 168)	θ value	0.0330416 (rank : 344)
Query Neighborhood Hits	747	Target Neighborhood Hits	256	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CD2A1_MOUSE
NC score	0.685205 (rank : 169)	θ value	0.000461057 (rank : 269)
Query Neighborhood Hits	747	Target Neighborhood Hits	206	Shared Neighborhood Hits	205
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

POT14_HUMAN
NC score	0.683640 (rank : 170)	θ value	1.43324e-05 (rank : 217)
Query Neighborhood Hits	747	Target Neighborhood Hits	403	Shared Neighborhood Hits	272
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ASB6_MOUSE
NC score	0.678941 (rank : 171)	θ value	0.21417 (rank : 404)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

NFKB2_MOUSE
NC score	0.677122 (rank : 172)	θ value	1.69304e-06 (rank : 190)
Query Neighborhood Hits	747	Target Neighborhood Hits	326	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR33_MOUSE
NC score	0.673022 (rank : 173)	θ value	2.44474e-05 (rank : 223)
Query Neighborhood Hits	747	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR25_HUMAN
NC score	0.666720 (rank : 174)	θ value	2.88788e-06 (rank : 193)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	272
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

OSTF1_MOUSE
NC score	0.660343 (rank : 175)	θ value	9.92553e-07 (rank : 183)
Query Neighborhood Hits	747	Target Neighborhood Hits	467	Shared Neighborhood Hits	299
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OSBL1_HUMAN
NC score	0.658821 (rank : 176)	θ value	8.67504e-11 (rank : 110)
Query Neighborhood Hits	747	Target Neighborhood Hits	368	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR25_MOUSE
NC score	0.657410 (rank : 177)	θ value	1.09739e-05 (rank : 211)
Query Neighborhood Hits	747	Target Neighborhood Hits	398	Shared Neighborhood Hits	284
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

MPP8_HUMAN
NC score	0.655053 (rank : 178)	θ value	9.59137e-10 (rank : 129)
Query Neighborhood Hits	747	Target Neighborhood Hits	948	Shared Neighborhood Hits	289
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR33_HUMAN
NC score	0.649507 (rank : 179)	θ value	0.000461057 (rank : 267)
Query Neighborhood Hits	747	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR38_HUMAN
NC score	0.648768 (rank : 180)	θ value	4.92598e-06 (rank : 199)
Query Neighborhood Hits	747	Target Neighborhood Hits	443	Shared Neighborhood Hits	254
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CDN2B_MOUSE
NC score	0.647382 (rank : 181)	θ value	8.40245e-06 (rank : 207)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

OSBL1_MOUSE
NC score	0.646974 (rank : 182)	θ value	6.21693e-09 (rank : 140)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	284
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSTF1_HUMAN
NC score	0.644242 (rank : 183)	θ value	7.59969e-07 (rank : 177)
Query Neighborhood Hits	747	Target Neighborhood Hits	466	Shared Neighborhood Hits	296
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

POT22_HUMAN
NC score	0.644114 (rank : 184)	θ value	1.43324e-05 (rank : 218)
Query Neighborhood Hits	747	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

CLPB_MOUSE
NC score	0.640407 (rank : 185)	θ value	0.0961366 (rank : 382)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

RAI14_HUMAN
NC score	0.635522 (rank : 186)	θ value	9.24701e-21 (rank : 32)
Query Neighborhood Hits	747	Target Neighborhood Hits	1367	Shared Neighborhood Hits	344
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

A20A3_HUMAN
NC score	0.629903 (rank : 187)	θ value	1.43324e-05 (rank : 215)
Query Neighborhood Hits	747	Target Neighborhood Hits	692	Shared Neighborhood Hits	294
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.629068 (rank : 188)	θ value	1.43324e-05 (rank : 214)
Query Neighborhood Hits	747	Target Neighborhood Hits	716	Shared Neighborhood Hits	294
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.628201 (rank : 189)	θ value	1.09739e-05 (rank : 210)
Query Neighborhood Hits	747	Target Neighborhood Hits	698	Shared Neighborhood Hits	290
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR45_MOUSE
NC score	0.627894 (rank : 190)	θ value	0.000270298 (rank : 258)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

A20A4_HUMAN
NC score	0.625284 (rank : 191)	θ value	1.43324e-05 (rank : 216)
Query Neighborhood Hits	747	Target Neighborhood Hits	710	Shared Neighborhood Hits	294
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR38_MOUSE
NC score	0.624605 (rank : 192)	θ value	3.19293e-05 (rank : 229)
Query Neighborhood Hits	747	Target Neighborhood Hits	512	Shared Neighborhood Hits	257
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CD2A1_HUMAN
NC score	0.619559 (rank : 193)	θ value	9.29e-05 (rank : 241)
Query Neighborhood Hits	747	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

RAI14_MOUSE
NC score	0.601336 (rank : 194)	θ value	2.27762e-19 (rank : 36)
Query Neighborhood Hits	747	Target Neighborhood Hits	1505	Shared Neighborhood Hits	339
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR43_MOUSE
NC score	0.594509 (rank : 195)	θ value	0.00390308 (rank : 297)
Query Neighborhood Hits	747	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_HUMAN
NC score	0.593824 (rank : 196)	θ value	0.0330416 (rank : 343)
Query Neighborhood Hits	747	Target Neighborhood Hits	209	Shared Neighborhood Hits	203
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR18_HUMAN
NC score	0.593655 (rank : 197)	θ value	2.79066e-09 (rank : 134)
Query Neighborhood Hits	747	Target Neighborhood Hits	1106	Shared Neighborhood Hits	305
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CDN2B_HUMAN
NC score	0.593627 (rank : 198)	θ value	0.0563607 (rank : 365)
Query Neighborhood Hits	747	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR45_HUMAN
NC score	0.586717 (rank : 199)	θ value	3.19293e-05 (rank : 230)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HECD1_HUMAN
NC score	0.586322 (rank : 200)	θ value	4.92598e-06 (rank : 201)
Query Neighborhood Hits	747	Target Neighborhood Hits	371	Shared Neighborhood Hits	274
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

RIPK4_HUMAN
NC score	0.582387 (rank : 201)	θ value	5.77852e-31 (rank : 7)
Query Neighborhood Hits	747	Target Neighborhood Hits	1094	Shared Neighborhood Hits	343
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_HUMAN
NC score	0.582166 (rank : 202)	θ value	1.62847e-25 (rank : 13)
Query Neighborhood Hits	747	Target Neighborhood Hits	1075	Shared Neighborhood Hits	335
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

IASPP_HUMAN
NC score	0.579567 (rank : 203)	θ value	0.000270298 (rank : 260)
Query Neighborhood Hits	747	Target Neighborhood Hits	688	Shared Neighborhood Hits	376
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ABTB2_HUMAN
NC score	0.578419 (rank : 204)	θ value	5.81887e-07 (rank : 175)
Query Neighborhood Hits	747	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
NC score	0.572455 (rank : 205)	θ value	6.43352e-06 (rank : 203)
Query Neighborhood Hits	747	Target Neighborhood Hits	1156	Shared Neighborhood Hits	374
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ASPP1_HUMAN
NC score	0.571861 (rank : 206)	θ value	7.1131e-05 (rank : 240)
Query Neighborhood Hits	747	Target Neighborhood Hits	956	Shared Neighborhood Hits	370
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NUD12_MOUSE
NC score	0.569305 (rank : 207)	θ value	1.09739e-05 (rank : 213)
Query Neighborhood Hits	747	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANKK1_MOUSE
NC score	0.568103 (rank : 208)	θ value	1.16704e-23 (rank : 15)
Query Neighborhood Hits	747	Target Neighborhood Hits	1072	Shared Neighborhood Hits	334
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ABTB2_MOUSE
NC score	0.564156 (rank : 209)	θ value	5.44631e-05 (rank : 235)
Query Neighborhood Hits	747	Target Neighborhood Hits	414	Shared Neighborhood Hits	239
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

AN30A_HUMAN
NC score	0.563985 (rank : 210)	θ value	9.59137e-10 (rank : 127)
Query Neighborhood Hits	747	Target Neighborhood Hits	1119	Shared Neighborhood Hits	312
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR40_HUMAN
NC score	0.557606 (rank : 211)	θ value	0.21417 (rank : 402)
Query Neighborhood Hits	747	Target Neighborhood Hits	224	Shared Neighborhood Hits	210
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ASPP1_MOUSE
NC score	0.557200 (rank : 212)	θ value	2.44474e-05 (rank : 224)
Query Neighborhood Hits	747	Target Neighborhood Hits	1244	Shared Neighborhood Hits	407
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CLPB_HUMAN
NC score	0.556172 (rank : 213)	θ value	0.21417 (rank : 406)
Query Neighborhood Hits	747	Target Neighborhood Hits	265	Shared Neighborhood Hits	233
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ILK2_HUMAN
NC score	0.555753 (rank : 214)	θ value	4.59992e-12 (rank : 99)
Query Neighborhood Hits	747	Target Neighborhood Hits	848	Shared Neighborhood Hits	317
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ANR40_MOUSE
NC score	0.555557 (rank : 215)	θ value	0.21417 (rank : 403)
Query Neighborhood Hits	747	Target Neighborhood Hits	228	Shared Neighborhood Hits	212
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CENB5_HUMAN
NC score	0.541233 (rank : 216)	θ value	9.92553e-07 (rank : 179)
Query Neighborhood Hits	747	Target Neighborhood Hits	395	Shared Neighborhood Hits	270
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ILK1_HUMAN
NC score	0.538500 (rank : 217)	θ value	4.59992e-12 (rank : 98)
Query Neighborhood Hits	747	Target Neighborhood Hits	857	Shared Neighborhood Hits	317
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.537455 (rank : 218)	θ value	2.69671e-12 (rank : 94)
Query Neighborhood Hits	747	Target Neighborhood Hits	858	Shared Neighborhood Hits	317
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

NUD12_HUMAN
NC score	0.534818 (rank : 219)	θ value	0.000602161 (rank : 275)
Query Neighborhood Hits	747	Target Neighborhood Hits	222	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV6_MOUSE
NC score	0.532281 (rank : 220)	θ value	0.000121331 (rank : 250)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

AN13B_MOUSE
NC score	0.531083 (rank : 221)	θ value	8.40245e-06 (rank : 206)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	251
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.530613 (rank : 222)	θ value	8.40245e-06 (rank : 205)
Query Neighborhood Hits	747	Target Neighborhood Hits	265	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CENB2_HUMAN
NC score	0.529513 (rank : 223)	θ value	5.44631e-05 (rank : 237)
Query Neighborhood Hits	747	Target Neighborhood Hits	425	Shared Neighborhood Hits	262
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB1_HUMAN
NC score	0.528270 (rank : 224)	θ value	0.0252991 (rank : 338)
Query Neighborhood Hits	747	Target Neighborhood Hits	383	Shared Neighborhood Hits	267
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ASB14_HUMAN
NC score	0.528097 (rank : 225)	θ value	0.00298849 (rank : 293)
Query Neighborhood Hits	747	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

IASPP_MOUSE
NC score	0.527061 (rank : 226)	θ value	0.000786445 (rank : 280)
Query Neighborhood Hits	747	Target Neighborhood Hits	1024	Shared Neighborhood Hits	401
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GLSL_HUMAN
NC score	0.526354 (rank : 227)	θ value	0.00035302 (rank : 264)
Query Neighborhood Hits	747	Target Neighborhood Hits	211	Shared Neighborhood Hits	204
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANKY1_HUMAN
NC score	0.525636 (rank : 228)	θ value	0.279714 (rank : 412)
Query Neighborhood Hits	747	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

GLSL_MOUSE
NC score	0.522995 (rank : 229)	θ value	3.19293e-05 (rank : 231)
Query Neighborhood Hits	747	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13C_HUMAN
NC score	0.519260 (rank : 230)	θ value	0.00390308 (rank : 295)
Query Neighborhood Hits	747	Target Neighborhood Hits	241	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
NC score	0.508493 (rank : 231)	θ value	0.00390308 (rank : 296)
Query Neighborhood Hits	747	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT2_MOUSE
NC score	0.497906 (rank : 232)	θ value	0.00175202 (rank : 285)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	258
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TRPV5_MOUSE
NC score	0.489157 (rank : 233)	θ value	8.40245e-06 (rank : 209)
Query Neighborhood Hits	747	Target Neighborhood Hits	278	Shared Neighborhood Hits	248
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

UACA_HUMAN
NC score	0.488023 (rank : 234)	θ value	1.133e-10 (rank : 113)
Query Neighborhood Hits	747	Target Neighborhood Hits	1622	Shared Neighborhood Hits	325
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

DDFL1_MOUSE
NC score	0.481749 (rank : 235)	θ value	3.77169e-06 (rank : 195)
Query Neighborhood Hits	747	Target Neighborhood Hits	324	Shared Neighborhood Hits	260
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GIT1_MOUSE
NC score	0.478829 (rank : 236)	θ value	0.0193708 (rank : 332)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	255
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GLSK_HUMAN
NC score	0.478623 (rank : 237)	θ value	0.00175202 (rank : 286)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GIT1_HUMAN
NC score	0.477721 (rank : 238)	θ value	0.0193708 (rank : 331)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	252
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

TNI3K_HUMAN
NC score	0.471967 (rank : 239)	θ value	8.36355e-22 (rank : 25)
Query Neighborhood Hits	747	Target Neighborhood Hits	1084	Shared Neighborhood Hits	341
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_MOUSE
NC score	0.471921 (rank : 240)	θ value	0.000461057 (rank : 272)
Query Neighborhood Hits	747	Target Neighborhood Hits	229	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

AN13A_HUMAN
NC score	0.467696 (rank : 241)	θ value	0.000121331 (rank : 246)
Query Neighborhood Hits	747	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

TNI3K_MOUSE
NC score	0.466393 (rank : 242)	θ value	7.0802e-21 (rank : 31)
Query Neighborhood Hits	747	Target Neighborhood Hits	1079	Shared Neighborhood Hits	340
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

GIT2_HUMAN
NC score	0.463073 (rank : 243)	θ value	0.00390308 (rank : 298)
Query Neighborhood Hits	747	Target Neighborhood Hits	381	Shared Neighborhood Hits	256
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

UACA_MOUSE
NC score	0.462982 (rank : 244)	θ value	1.63604e-09 (rank : 131)
Query Neighborhood Hits	747	Target Neighborhood Hits	1620	Shared Neighborhood Hits	327
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

NOTC4_MOUSE
NC score	0.449520 (rank : 245)	θ value	2.60593e-15 (rank : 67)
Query Neighborhood Hits	747	Target Neighborhood Hits	872	Shared Neighborhood Hits	306
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV6_HUMAN
NC score	0.448874 (rank : 246)	θ value	0.00102713 (rank : 281)
Query Neighborhood Hits	747	Target Neighborhood Hits	262	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

NOTC4_HUMAN
NC score	0.444645 (rank : 247)	θ value	8.95645e-16 (rank : 63)
Query Neighborhood Hits	747	Target Neighborhood Hits	905	Shared Neighborhood Hits	316
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV5_HUMAN
NC score	0.443956 (rank : 248)	θ value	0.00869519 (rank : 315)
Query Neighborhood Hits	747	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13A_MOUSE
NC score	0.440119 (rank : 249)	θ value	0.00298849 (rank : 292)
Query Neighborhood Hits	747	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

ANR26_MOUSE
NC score	0.439595 (rank : 250)	θ value	7.59969e-07 (rank : 176)
Query Neighborhood Hits	747	Target Neighborhood Hits	1554	Shared Neighborhood Hits	331
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CT012_HUMAN
NC score	0.435143 (rank : 251)	θ value	0.000786445 (rank : 277)
Query Neighborhood Hits	747	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDEF2_HUMAN
NC score	0.421918 (rank : 252)	θ value	9.29e-05 (rank : 243)
Query Neighborhood Hits	747	Target Neighborhood Hits	599	Shared Neighborhood Hits	326
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ANR26_HUMAN
NC score	0.419988 (rank : 253)	θ value	6.43352e-06 (rank : 202)
Query Neighborhood Hits	747	Target Neighborhood Hits	1614	Shared Neighborhood Hits	335
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DDEF2_MOUSE
NC score	0.418636 (rank : 254)	θ value	9.29e-05 (rank : 244)
Query Neighborhood Hits	747	Target Neighborhood Hits	625	Shared Neighborhood Hits	331
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DAPK1_MOUSE
NC score	0.413397 (rank : 255)	θ value	6.40375e-22 (rank : 24)
Query Neighborhood Hits	747	Target Neighborhood Hits	1138	Shared Neighborhood Hits	342
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_MOUSE
NC score	0.406598 (rank : 256)	θ value	0.0113563 (rank : 323)
Query Neighborhood Hits	747	Target Neighborhood Hits	1333	Shared Neighborhood Hits	327
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_HUMAN
NC score	0.405954 (rank : 257)	θ value	0.163984 (rank : 401)
Query Neighborhood Hits	747	Target Neighborhood Hits	1103	Shared Neighborhood Hits	304
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DAPK1_HUMAN
NC score	0.405785 (rank : 258)	θ value	1.6852e-22 (rank : 22)
Query Neighborhood Hits	747	Target Neighborhood Hits	1130	Shared Neighborhood Hits	336
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC3_MOUSE
NC score	0.402836 (rank : 259)	θ value	1.99992e-07 (rank : 164)
Query Neighborhood Hits	747	Target Neighborhood Hits	975	Shared Neighborhood Hits	343
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.401032 (rank : 260)	θ value	2.61198e-07 (rank : 167)
Query Neighborhood Hits	747	Target Neighborhood Hits	1062	Shared Neighborhood Hits	349
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.395459 (rank : 261)	θ value	8.97725e-08 (rank : 161)
Query Neighborhood Hits	747	Target Neighborhood Hits	1113	Shared Neighborhood Hits	348
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.394362 (rank : 262)	θ value	4.45536e-07 (rank : 173)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	307
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.391630 (rank : 263)	θ value	4.0297e-08 (rank : 156)
Query Neighborhood Hits	747	Target Neighborhood Hits	1069	Shared Neighborhood Hits	325
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DDFL1_HUMAN
NC score	0.390505 (rank : 264)	θ value	0.00134147 (rank : 282)
Query Neighborhood Hits	747	Target Neighborhood Hits	353	Shared Neighborhood Hits	251
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_HUMAN
NC score	0.360817 (rank : 265)	θ value	0.163984 (rank : 396)
Query Neighborhood Hits	747	Target Neighborhood Hits	551	Shared Neighborhood Hits	223
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_MOUSE
NC score	0.352642 (rank : 266)	θ value	1.38821 (rank : 527)
Query Neighborhood Hits	747	Target Neighborhood Hits	531	Shared Neighborhood Hits	299
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.350814 (rank : 267)	θ value	0.813845 (rank : 471)
Query Neighborhood Hits	747	Target Neighborhood Hits	544	Shared Neighborhood Hits	302
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ANKZ1_MOUSE
NC score	0.346091 (rank : 268)	θ value	0.00665767 (rank : 301)
Query Neighborhood Hits	747	Target Neighborhood Hits	208	Shared Neighborhood Hits	154
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

DGKZ_MOUSE
NC score	0.345390 (rank : 269)	θ value	0.00869519 (rank : 308)
Query Neighborhood Hits	747	Target Neighborhood Hits	542	Shared Neighborhood Hits	211
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
NC score	0.342455 (rank : 270)	θ value	0.0431538 (rank : 359)
Query Neighborhood Hits	747	Target Neighborhood Hits	609	Shared Neighborhood Hits	227
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CENG2_HUMAN
NC score	0.340861 (rank : 271)	θ value	0.365318 (rank : 423)
Query Neighborhood Hits	747	Target Neighborhood Hits	471	Shared Neighborhood Hits	260
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

DDEF1_MOUSE
NC score	0.338067 (rank : 272)	θ value	9.29e-05 (rank : 242)
Query Neighborhood Hits	747	Target Neighborhood Hits	592	Shared Neighborhood Hits	272
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CENG2_MOUSE
NC score	0.337975 (rank : 273)	θ value	0.47712 (rank : 436)
Query Neighborhood Hits	747	Target Neighborhood Hits	463	Shared Neighborhood Hits	256
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

NOTC1_MOUSE
NC score	0.334233 (rank : 274)	θ value	0.000270298 (rank : 261)
Query Neighborhood Hits	747	Target Neighborhood Hits	916	Shared Neighborhood Hits	291
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKZ1_HUMAN
NC score	0.323753 (rank : 275)	θ value	1.06291 (rank : 494)
Query Neighborhood Hits	747	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

CENG3_HUMAN
NC score	0.314313 (rank : 276)	θ value	0.000461057 (rank : 270)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	238
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
NC score	0.314227 (rank : 277)	θ value	0.000461057 (rank : 271)
Query Neighborhood Hits	747	Target Neighborhood Hits	467	Shared Neighborhood Hits	237
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

IKBL_HUMAN
NC score	0.311060 (rank : 278)	θ value	8.99809 (rank : 718)
Query Neighborhood Hits	747	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.304101 (rank : 279)	θ value	8.99809 (rank : 719)
Query Neighborhood Hits	747	Target Neighborhood Hits	196	Shared Neighborhood Hits	142
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CLR59_HUMAN
NC score	0.297721 (rank : 280)	θ value	0.0113563 (rank : 316)
Query Neighborhood Hits	747	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ABTB1_MOUSE
NC score	0.281569 (rank : 281)	θ value	2.36792 (rank : 554)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	178
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ANKR9_MOUSE
NC score	0.256551 (rank : 282)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	747	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_MOUSE
NC score	0.249423 (rank : 283)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

RSNL2_HUMAN
NC score	0.244056 (rank : 284)	θ value	0.813845 (rank : 487)
Query Neighborhood Hits	747	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ABTB1_HUMAN
NC score	0.237275 (rank : 285)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	747	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV1_MOUSE
NC score	0.229631 (rank : 286)	θ value	2.36792 (rank : 584)
Query Neighborhood Hits	747	Target Neighborhood Hits	189	Shared Neighborhood Hits	156
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV3_HUMAN
NC score	0.219867 (rank : 287)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	747	Target Neighborhood Hits	198	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

BAT4_HUMAN
NC score	0.217250 (rank : 288)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	747	Target Neighborhood Hits	157	Shared Neighborhood Hits	112
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

TRPV3_MOUSE
NC score	0.216930 (rank : 289)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	133
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_HUMAN
NC score	0.208290 (rank : 290)	θ value	6.88961 (rank : 699)
Query Neighborhood Hits	747	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_HUMAN
NC score	0.206831 (rank : 291)	θ value	0.0563607 (rank : 373)
Query Neighborhood Hits	747	Target Neighborhood Hits	130	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ANKR9_HUMAN
NC score	0.206143 (rank : 292)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	747	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CMTA1_HUMAN
NC score	0.201704 (rank : 293)	θ value	3.0926 (rank : 588)
Query Neighborhood Hits	747	Target Neighborhood Hits	217	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RSNL2_MOUSE
NC score	0.201280 (rank : 294)	θ value	6.88961 (rank : 689)
Query Neighborhood Hits	747	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

PRP1_HUMAN
NC score	0.186293 (rank : 295)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	747	Target Neighborhood Hits	385	Shared Neighborhood Hits	179
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CMTA2_HUMAN
NC score	0.175602 (rank : 296)	θ value	3.0926 (rank : 589)
Query Neighborhood Hits	747	Target Neighborhood Hits	199	Shared Neighborhood Hits	123
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

PRP2_MOUSE
NC score	0.175099 (rank : 297)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	747	Target Neighborhood Hits	347	Shared Neighborhood Hits	164
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRB4S_HUMAN
NC score	0.171741 (rank : 298)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	747	Target Neighborhood Hits	330	Shared Neighborhood Hits	162
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

TRPV2_MOUSE
NC score	0.164392 (rank : 299)	θ value	0.0193708 (rank : 337)
Query Neighborhood Hits	747	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

WASIP_HUMAN
NC score	0.164056 (rank : 300)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	747	Target Neighborhood Hits	458	Shared Neighborhood Hits	192
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CMTA2_MOUSE
NC score	0.162259 (rank : 301)	θ value	1.81305 (rank : 541)
Query Neighborhood Hits	747	Target Neighborhood Hits	216	Shared Neighborhood Hits	117
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

PRB3_HUMAN
NC score	0.160624 (rank : 302)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	151
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

WASIP_MOUSE
NC score	0.144253 (rank : 303)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	747	Target Neighborhood Hits	392	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PRR12_HUMAN
NC score	0.138615 (rank : 304)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	747	Target Neighborhood Hits	460	Shared Neighborhood Hits	182
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TAF4_HUMAN
NC score	0.137819 (rank : 305)	θ value	2.36792 (rank : 582)
Query Neighborhood Hits	747	Target Neighborhood Hits	687	Shared Neighborhood Hits	193
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

NACAM_MOUSE
NC score	0.137573 (rank : 306)	θ value	6.43352e-06 (rank : 204)
Query Neighborhood Hits	747	Target Neighborhood Hits	1866	Shared Neighborhood Hits	288
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GSCR1_HUMAN
NC score	0.136504 (rank : 307)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	747	Target Neighborhood Hits	674	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SRRM1_MOUSE
NC score	0.136128 (rank : 308)	θ value	0.47712 (rank : 446)
Query Neighborhood Hits	747	Target Neighborhood Hits	966	Shared Neighborhood Hits	193
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MUC7_HUMAN
NC score	0.133531 (rank : 309)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	747	Target Neighborhood Hits	538	Shared Neighborhood Hits	181
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

LRRK1_MOUSE
NC score	0.132251 (rank : 310)	θ value	9.92553e-07 (rank : 181)
Query Neighborhood Hits	747	Target Neighborhood Hits	1267	Shared Neighborhood Hits	172
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

SRRM1_HUMAN
NC score	0.131658 (rank : 311)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	747	Target Neighborhood Hits	690	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BAT2_HUMAN
NC score	0.128219 (rank : 312)	θ value	0.47712 (rank : 434)
Query Neighborhood Hits	747	Target Neighborhood Hits	931	Shared Neighborhood Hits	227
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TRPC6_HUMAN
NC score	0.127764 (rank : 313)	θ value	0.0736092 (rank : 381)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

ANKF1_HUMAN
NC score	0.127559 (rank : 314)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	747	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

OGFR_HUMAN
NC score	0.125521 (rank : 315)	θ value	1.29631e-06 (rank : 185)
Query Neighborhood Hits	747	Target Neighborhood Hits	1582	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

WIRE_MOUSE
NC score	0.124383 (rank : 316)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	747	Target Neighborhood Hits	310	Shared Neighborhood Hits	140
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MUC1_HUMAN
NC score	0.124344 (rank : 317)	θ value	3.07829e-16 (rank : 58)
Query Neighborhood Hits	747	Target Neighborhood Hits	975	Shared Neighborhood Hits	173
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SASH1_MOUSE
NC score	0.124195 (rank : 318)	θ value	0.00869519 (rank : 314)
Query Neighborhood Hits	747	Target Neighborhood Hits	263	Shared Neighborhood Hits	96
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

MBD6_HUMAN
NC score	0.124150 (rank : 319)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

SASH1_HUMAN
NC score	0.122425 (rank : 320)	θ value	0.00665767 (rank : 306)
Query Neighborhood Hits	747	Target Neighborhood Hits	292	Shared Neighborhood Hits	123
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SRRM2_HUMAN
NC score	0.122029 (rank : 321)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	747	Target Neighborhood Hits	1296	Shared Neighborhood Hits	237
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PRRT3_HUMAN
NC score	0.121854 (rank : 322)	θ value	2.44474e-05 (rank : 228)
Query Neighborhood Hits	747	Target Neighborhood Hits	998	Shared Neighborhood Hits	183
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WIRE_HUMAN
NC score	0.120483 (rank : 323)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	747	Target Neighborhood Hits	329	Shared Neighborhood Hits	146
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SHAN2_MOUSE
NC score	0.120451 (rank : 324)	θ value	0.0736092 (rank : 380)
Query Neighborhood Hits	747	Target Neighborhood Hits	446	Shared Neighborhood Hits	134
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

MDC1_HUMAN
NC score	0.119713 (rank : 325)	θ value	0.0330416 (rank : 352)
Query Neighborhood Hits	747	Target Neighborhood Hits	1446	Shared Neighborhood Hits	209
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRG4_HUMAN
NC score	0.119503 (rank : 326)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	747	Target Neighborhood Hits	764	Shared Neighborhood Hits	187
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

BSN_MOUSE
NC score	0.117198 (rank : 327)	θ value	0.0431538 (rank : 358)
Query Neighborhood Hits	747	Target Neighborhood Hits	2057	Shared Neighborhood Hits	306
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

TRPV4_HUMAN
NC score	0.114272 (rank : 328)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	747	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

SHAN2_HUMAN
NC score	0.114062 (rank : 329)	θ value	0.0736092 (rank : 379)
Query Neighborhood Hits	747	Target Neighborhood Hits	346	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

ATN1_HUMAN
NC score	0.113292 (rank : 330)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	747	Target Neighborhood Hits	676	Shared Neighborhood Hits	190
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CN032_HUMAN
NC score	0.112754 (rank : 331)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

BSN_HUMAN
NC score	0.112400 (rank : 332)	θ value	1.06291 (rank : 496)
Query Neighborhood Hits	747	Target Neighborhood Hits	1537	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PCLO_HUMAN
NC score	0.112385 (rank : 333)	θ value	0.365318 (rank : 429)
Query Neighborhood Hits	747	Target Neighborhood Hits	2046	Shared Neighborhood Hits	304
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NCOA6_HUMAN
NC score	0.112309 (rank : 334)	θ value	0.00298849 (rank : 294)
Query Neighborhood Hits	747	Target Neighborhood Hits	1202	Shared Neighborhood Hits	216
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TRPC3_HUMAN
NC score	0.112026 (rank : 335)	θ value	0.00665767 (rank : 307)
Query Neighborhood Hits	747	Target Neighborhood Hits	137	Shared Neighborhood Hits	82
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

BAT2_MOUSE
NC score	0.111743 (rank : 336)	θ value	0.47712 (rank : 435)
Query Neighborhood Hits	747	Target Neighborhood Hits	947	Shared Neighborhood Hits	233
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SRRM2_MOUSE
NC score	0.111610 (rank : 337)	θ value	0.0330416 (rank : 357)
Query Neighborhood Hits	747	Target Neighborhood Hits	1470	Shared Neighborhood Hits	235
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BASP_MOUSE
NC score	0.111195 (rank : 338)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	80
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MLL2_HUMAN
NC score	0.109744 (rank : 339)	θ value	1.38821 (rank : 537)
Query Neighborhood Hits	747	Target Neighborhood Hits	1788	Shared Neighborhood Hits	292
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

WBP11_MOUSE
NC score	0.109364 (rank : 340)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	747	Target Neighborhood Hits	362	Shared Neighborhood Hits	137
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

LRRK1_HUMAN
NC score	0.108697 (rank : 341)	θ value	9.29e-05 (rank : 245)
Query Neighborhood Hits	747	Target Neighborhood Hits	1237	Shared Neighborhood Hits	147
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

SARM1_MOUSE
NC score	0.108467 (rank : 342)	θ value	0.00869519 (rank : 313)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

EPHB6_HUMAN
NC score	0.107917 (rank : 343)	θ value	0.00665767 (rank : 303)
Query Neighborhood Hits	747	Target Neighborhood Hits	912	Shared Neighborhood Hits	90
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
NC score	0.107645 (rank : 344)	θ value	0.00228821 (rank : 289)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	87
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA5_HUMAN
NC score	0.107520 (rank : 345)	θ value	3.77169e-06 (rank : 196)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

WBP11_HUMAN
NC score	0.107163 (rank : 346)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	747	Target Neighborhood Hits	354	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

EPHA6_HUMAN
NC score	0.107095 (rank : 347)	θ value	0.00020696 (rank : 254)
Query Neighborhood Hits	747	Target Neighborhood Hits	959	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

SON_HUMAN
NC score	0.107031 (rank : 348)	θ value	0.000461057 (rank : 274)
Query Neighborhood Hits	747	Target Neighborhood Hits	1568	Shared Neighborhood Hits	244
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

YLPM1_MOUSE
NC score	0.106990 (rank : 349)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	747	Target Neighborhood Hits	505	Shared Neighborhood Hits	157
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CEND3_HUMAN
NC score	0.106215 (rank : 350)	θ value	0.0563607 (rank : 366)
Query Neighborhood Hits	747	Target Neighborhood Hits	275	Shared Neighborhood Hits	108
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

MDC1_MOUSE
NC score	0.106155 (rank : 351)	θ value	0.00665767 (rank : 305)
Query Neighborhood Hits	747	Target Neighborhood Hits	998	Shared Neighborhood Hits	180
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL3_MOUSE
NC score	0.106097 (rank : 352)	θ value	3.77169e-06 (rank : 198)
Query Neighborhood Hits	747	Target Neighborhood Hits	1399	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

EPHA6_MOUSE
NC score	0.105565 (rank : 353)	θ value	0.000270298 (rank : 259)
Query Neighborhood Hits	747	Target Neighborhood Hits	946	Shared Neighborhood Hits	80
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB3_HUMAN
NC score	0.105311 (rank : 354)	θ value	3.77169e-06 (rank : 197)
Query Neighborhood Hits	747	Target Neighborhood Hits	996	Shared Neighborhood Hits	90
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA7_HUMAN
NC score	0.105309 (rank : 355)	θ value	1.87187e-05 (rank : 222)
Query Neighborhood Hits	747	Target Neighborhood Hits	1053	Shared Neighborhood Hits	94
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

TRPV4_MOUSE
NC score	0.104995 (rank : 356)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	747	Target Neighborhood Hits	117	Shared Neighborhood Hits	79
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

PCLO_MOUSE
NC score	0.104984 (rank : 357)	θ value	0.00869519 (rank : 311)
Query Neighborhood Hits	747	Target Neighborhood Hits	2275	Shared Neighborhood Hits	314
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EPHA1_MOUSE
NC score	0.104953 (rank : 358)	θ value	1.09739e-05 (rank : 212)
Query Neighborhood Hits	747	Target Neighborhood Hits	958	Shared Neighborhood Hits	87
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA1_HUMAN
NC score	0.104930 (rank : 359)	θ value	1.87187e-05 (rank : 221)
Query Neighborhood Hits	747	Target Neighborhood Hits	997	Shared Neighborhood Hits	94
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

CPSF6_MOUSE
NC score	0.104910 (rank : 360)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	747	Target Neighborhood Hits	356	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

PRP5_HUMAN
NC score	0.104760 (rank : 361)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	747	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

CN032_MOUSE
NC score	0.104753 (rank : 362)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	747	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

EPHA2_MOUSE
NC score	0.104388 (rank : 363)	θ value	1.69304e-06 (rank : 188)
Query Neighborhood Hits	747	Target Neighborhood Hits	1020	Shared Neighborhood Hits	89
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA7_MOUSE
NC score	0.104374 (rank : 364)	θ value	4.1701e-05 (rank : 233)
Query Neighborhood Hits	747	Target Neighborhood Hits	1025	Shared Neighborhood Hits	89
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHA2_HUMAN
NC score	0.104268 (rank : 365)	θ value	9.92553e-07 (rank : 180)
Query Neighborhood Hits	747	Target Neighborhood Hits	1021	Shared Neighborhood Hits	89
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHB4_HUMAN
NC score	0.104256 (rank : 366)	θ value	5.44631e-05 (rank : 238)
Query Neighborhood Hits	747	Target Neighborhood Hits	1056	Shared Neighborhood Hits	94
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

BCL9_MOUSE
NC score	0.104096 (rank : 367)	θ value	0.0193708 (rank : 330)
Query Neighborhood Hits	747	Target Neighborhood Hits	770	Shared Neighborhood Hits	173
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

EPHB3_MOUSE
NC score	0.104078 (rank : 368)	θ value	8.40245e-06 (rank : 208)
Query Neighborhood Hits	747	Target Neighborhood Hits	996	Shared Neighborhood Hits	87
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB2_HUMAN
NC score	0.104032 (rank : 369)	θ value	0.00035302 (rank : 262)
Query Neighborhood Hits	747	Target Neighborhood Hits	983	Shared Neighborhood Hits	87
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

CPSF6_HUMAN
NC score	0.103796 (rank : 370)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	747	Target Neighborhood Hits	359	Shared Neighborhood Hits	139
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

EPHAA_HUMAN
NC score	0.103721 (rank : 371)	θ value	0.00175202 (rank : 284)
Query Neighborhood Hits	747	Target Neighborhood Hits	960	Shared Neighborhood Hits	83
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

MLL3_HUMAN
NC score	0.103510 (rank : 372)	θ value	0.00228821 (rank : 291)
Query Neighborhood Hits	747	Target Neighborhood Hits	1644	Shared Neighborhood Hits	222
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NCOA6_MOUSE
NC score	0.103415 (rank : 373)	θ value	0.163984 (rank : 398)
Query Neighborhood Hits	747	Target Neighborhood Hits	1076	Shared Neighborhood Hits	194
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

EPHB4_MOUSE
NC score	0.103148 (rank : 374)	θ value	0.000121331 (rank : 248)
Query Neighborhood Hits	747	Target Neighborhood Hits	1013	Shared Neighborhood Hits	90
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

TARSH_HUMAN
NC score	0.103049 (rank : 375)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	747	Target Neighborhood Hits	768	Shared Neighborhood Hits	170
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

EPHA8_MOUSE
NC score	0.102942 (rank : 376)	θ value	0.000786445 (rank : 279)
Query Neighborhood Hits	747	Target Neighborhood Hits	969	Shared Neighborhood Hits	82
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

SF3A2_MOUSE
NC score	0.102883 (rank : 377)	θ value	8.99809 (rank : 731)
Query Neighborhood Hits	747	Target Neighborhood Hits	247	Shared Neighborhood Hits	113
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

EPHB2_MOUSE
NC score	0.102649 (rank : 378)	θ value	0.00035302 (rank : 263)
Query Neighborhood Hits	747	Target Neighborhood Hits	982	Shared Neighborhood Hits	87
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

PRG4_MOUSE
NC score	0.102314 (rank : 379)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	747	Target Neighborhood Hits	624	Shared Neighborhood Hits	153
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TRPC3_MOUSE
NC score	0.102145 (rank : 380)	θ value	0.0563607 (rank : 372)
Query Neighborhood Hits	747	Target Neighborhood Hits	131	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

EPHB1_HUMAN
NC score	0.101313 (rank : 381)	θ value	4.1701e-05 (rank : 234)
Query Neighborhood Hits	747	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

GGN_MOUSE
NC score	0.101244 (rank : 382)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	747	Target Neighborhood Hits	311	Shared Neighborhood Hits	123
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

RAPH1_HUMAN
NC score	0.101027 (rank : 383)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	747	Target Neighborhood Hits	593	Shared Neighborhood Hits	194
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

EPHA8_HUMAN
NC score	0.100898 (rank : 384)	θ value	0.000786445 (rank : 278)
Query Neighborhood Hits	747	Target Neighborhood Hits	956	Shared Neighborhood Hits	81
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

BCL9_HUMAN
NC score	0.100793 (rank : 385)	θ value	0.00175202 (rank : 283)
Query Neighborhood Hits	747	Target Neighborhood Hits	1008	Shared Neighborhood Hits	195
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SET1A_HUMAN
NC score	0.100715 (rank : 386)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	747	Target Neighborhood Hits	690	Shared Neighborhood Hits	168
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CEND3_MOUSE
NC score	0.100377 (rank : 387)	θ value	0.125558 (rank : 389)
Query Neighborhood Hits	747	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CN155_HUMAN
NC score	0.099856 (rank : 388)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	747	Target Neighborhood Hits	385	Shared Neighborhood Hits	104
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

RERE_MOUSE
NC score	0.099847 (rank : 389)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	747	Target Neighborhood Hits	785	Shared Neighborhood Hits	210
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

BASP_HUMAN
NC score	0.099586 (rank : 390)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	747	Target Neighborhood Hits	321	Shared Neighborhood Hits	95
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TRPC6_MOUSE
NC score	0.099505 (rank : 391)	θ value	0.62314 (rank : 463)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

EPHA4_MOUSE
NC score	0.099320 (rank : 392)	θ value	0.0148317 (rank : 326)
Query Neighborhood Hits	747	Target Neighborhood Hits	982	Shared Neighborhood Hits	86
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

TRPC7_HUMAN
NC score	0.099258 (rank : 393)	θ value	0.0113563 (rank : 324)
Query Neighborhood Hits	747	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

MAGE1_HUMAN
NC score	0.099122 (rank : 394)	θ value	2.13673e-09 (rank : 133)
Query Neighborhood Hits	747	Target Neighborhood Hits	1389	Shared Neighborhood Hits	231
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

EPHA4_HUMAN
NC score	0.099116 (rank : 395)	θ value	0.0113563 (rank : 318)
Query Neighborhood Hits	747	Target Neighborhood Hits	975	Shared Neighborhood Hits	85
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

CJ078_MOUSE
NC score	0.098893 (rank : 396)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	747	Target Neighborhood Hits	559	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

EPHA5_MOUSE
NC score	0.097873 (rank : 397)	θ value	2.44474e-05 (rank : 225)
Query Neighborhood Hits	747	Target Neighborhood Hits	950	Shared Neighborhood Hits	86
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

TRPC7_MOUSE
NC score	0.097740 (rank : 398)	θ value	0.0431538 (rank : 363)
Query Neighborhood Hits	747	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

YLPM1_HUMAN
NC score	0.097500 (rank : 399)	θ value	0.279714 (rank : 421)
Query Neighborhood Hits	747	Target Neighborhood Hits	670	Shared Neighborhood Hits	162
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

RERE_HUMAN
NC score	0.097058 (rank : 400)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	747	Target Neighborhood Hits	779	Shared Neighborhood Hits	204
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SAM14_MOUSE
NC score	0.096113 (rank : 401)	θ value	0.0113563 (rank : 322)
Query Neighborhood Hits	747	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

MLL4_HUMAN
NC score	0.095970 (rank : 402)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	747	Target Neighborhood Hits	722	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SF3A2_HUMAN
NC score	0.095965 (rank : 403)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	747	Target Neighborhood Hits	263	Shared Neighborhood Hits	117
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

K1543_MOUSE
NC score	0.095821 (rank : 404)	θ value	0.000461057 (rank : 273)
Query Neighborhood Hits	747	Target Neighborhood Hits	497	Shared Neighborhood Hits	110
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SYN1_HUMAN
NC score	0.095765 (rank : 405)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	747	Target Neighborhood Hits	419	Shared Neighborhood Hits	191
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SARM1_HUMAN
NC score	0.095213 (rank : 406)	θ value	0.0148317 (rank : 327)
Query Neighborhood Hits	747	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

ENAH_MOUSE
NC score	0.094998 (rank : 407)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	747	Target Neighborhood Hits	919	Shared Neighborhood Hits	211
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

RGS3_MOUSE
NC score	0.094919 (rank : 408)	θ value	0.00020696 (rank : 255)
Query Neighborhood Hits	747	Target Neighborhood Hits	1621	Shared Neighborhood Hits	243
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SAM14_HUMAN
NC score	0.091861 (rank : 409)	θ value	0.0193708 (rank : 335)
Query Neighborhood Hits	747	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SON_MOUSE
NC score	0.091818 (rank : 410)	θ value	0.0431538 (rank : 362)
Query Neighborhood Hits	747	Target Neighborhood Hits	957	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

GRIN1_HUMAN
NC score	0.091445 (rank : 411)	θ value	1.38821 (rank : 530)
Query Neighborhood Hits	747	Target Neighborhood Hits	681	Shared Neighborhood Hits	157
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PRPE_HUMAN
NC score	0.090190 (rank : 412)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	747	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

EPHA3_HUMAN
NC score	0.089689 (rank : 413)	θ value	4.03905 (rank : 615)
Query Neighborhood Hits	747	Target Neighborhood Hits	1005	Shared Neighborhood Hits	76
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
NC score	0.089469 (rank : 414)	θ value	5.27518 (rank : 647)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	75
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

CS016_HUMAN
NC score	0.089447 (rank : 415)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	747	Target Neighborhood Hits	310	Shared Neighborhood Hits	103
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

TCOF_MOUSE
NC score	0.087572 (rank : 416)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	747	Target Neighborhood Hits	471	Shared Neighborhood Hits	120
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PRPC_HUMAN
NC score	0.087435 (rank : 417)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	747	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

MUCDL_HUMAN
NC score	0.086971 (rank : 418)	θ value	0.0431538 (rank : 360)
Query Neighborhood Hits	747	Target Neighborhood Hits	777	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SYN1_MOUSE
NC score	0.086829 (rank : 419)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	747	Target Neighborhood Hits	363	Shared Neighborhood Hits	169
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

NFH_MOUSE
NC score	0.086647 (rank : 420)	θ value	5.44631e-05 (rank : 239)
Query Neighborhood Hits	747	Target Neighborhood Hits	2247	Shared Neighborhood Hits	270
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GGN_HUMAN
NC score	0.086636 (rank : 421)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	112
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CEND1_HUMAN
NC score	0.086416 (rank : 422)	θ value	0.813845 (rank : 469)
Query Neighborhood Hits	747	Target Neighborhood Hits	284	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

WASL_MOUSE
NC score	0.086270 (rank : 423)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	747	Target Neighborhood Hits	339	Shared Neighborhood Hits	148
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN207_HUMAN
NC score	0.086111 (rank : 424)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	747	Target Neighborhood Hits	326	Shared Neighborhood Hits	91
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

TXND2_HUMAN
NC score	0.085268 (rank : 425)	θ value	0.00020696 (rank : 256)
Query Neighborhood Hits	747	Target Neighborhood Hits	793	Shared Neighborhood Hits	116
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MARCS_HUMAN
NC score	0.085055 (rank : 426)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

ALEX_HUMAN
NC score	0.084926 (rank : 427)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	116
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

NOLC1_HUMAN
NC score	0.084921 (rank : 428)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	747	Target Neighborhood Hits	452	Shared Neighborhood Hits	98
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

WASL_HUMAN
NC score	0.084856 (rank : 429)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	145
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MUC2_HUMAN
NC score	0.084625 (rank : 430)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	184
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TCGAP_HUMAN
NC score	0.084548 (rank : 431)	θ value	9.92553e-07 (rank : 184)
Query Neighborhood Hits	747	Target Neighborhood Hits	872	Shared Neighborhood Hits	182
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SFPQ_MOUSE
NC score	0.084184 (rank : 432)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	747	Target Neighborhood Hits	958	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

NU214_HUMAN
NC score	0.084046 (rank : 433)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	747	Target Neighborhood Hits	657	Shared Neighborhood Hits	136
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

LAD1_MOUSE
NC score	0.084008 (rank : 434)	θ value	0.00228821 (rank : 290)
Query Neighborhood Hits	747	Target Neighborhood Hits	391	Shared Neighborhood Hits	76
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

CIC_HUMAN
NC score	0.083889 (rank : 435)	θ value	2.36792 (rank : 558)
Query Neighborhood Hits	747	Target Neighborhood Hits	992	Shared Neighborhood Hits	218
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MUC1_MOUSE
NC score	0.083677 (rank : 436)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	747	Target Neighborhood Hits	388	Shared Neighborhood Hits	76
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

K1802_MOUSE
NC score	0.083669 (rank : 437)	θ value	3.19293e-05 (rank : 232)
Query Neighborhood Hits	747	Target Neighborhood Hits	1596	Shared Neighborhood Hits	209
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MARCS_MOUSE
NC score	0.083586 (rank : 438)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	747	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PRR13_HUMAN
NC score	0.082650 (rank : 439)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	747	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SMR3A_HUMAN
NC score	0.082552 (rank : 440)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	747	Target Neighborhood Hits	93	Shared Neighborhood Hits	47
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

CK024_HUMAN
NC score	0.082376 (rank : 441)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	747	Target Neighborhood Hits	408	Shared Neighborhood Hits	99
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

GRIN1_MOUSE
NC score	0.082159 (rank : 442)	θ value	0.0330416 (rank : 350)
Query Neighborhood Hits	747	Target Neighborhood Hits	337	Shared Neighborhood Hits	104
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CBP_HUMAN
NC score	0.082104 (rank : 443)	θ value	6.88961 (rank : 671)
Query Neighborhood Hits	747	Target Neighborhood Hits	941	Shared Neighborhood Hits	197
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DGKD_HUMAN
NC score	0.082059 (rank : 444)	θ value	0.279714 (rank : 414)
Query Neighborhood Hits	747	Target Neighborhood Hits	231	Shared Neighborhood Hits	68
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

FMNL_HUMAN
NC score	0.081871 (rank : 445)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	747	Target Neighborhood Hits	529	Shared Neighborhood Hits	164
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TM108_MOUSE
NC score	0.081635 (rank : 446)	θ value	0.125558 (rank : 393)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CS007_MOUSE
NC score	0.081577 (rank : 447)	θ value	5.27518 (rank : 644)
Query Neighborhood Hits	747	Target Neighborhood Hits	464	Shared Neighborhood Hits	134
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CBP_MOUSE
NC score	0.081358 (rank : 448)	θ value	5.27518 (rank : 642)
Query Neighborhood Hits	747	Target Neighborhood Hits	1051	Shared Neighborhood Hits	210
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TM108_HUMAN
NC score	0.080959 (rank : 449)	θ value	0.47712 (rank : 449)
Query Neighborhood Hits	747	Target Neighborhood Hits	166	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CABIN_HUMAN
NC score	0.080848 (rank : 450)	θ value	0.125558 (rank : 387)
Query Neighborhood Hits	747	Target Neighborhood Hits	490	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SFPQ_HUMAN
NC score	0.080801 (rank : 451)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	747	Target Neighborhood Hits	986	Shared Neighborhood Hits	222
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TCOF_HUMAN
NC score	0.080639 (rank : 452)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	747	Target Neighborhood Hits	543	Shared Neighborhood Hits	122
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CEND1_MOUSE
NC score	0.080358 (rank : 453)	θ value	0.813845 (rank : 470)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

MUC13_MOUSE
NC score	0.080188 (rank : 454)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	747	Target Neighborhood Hits	447	Shared Neighborhood Hits	100
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

WASP_MOUSE
NC score	0.080178 (rank : 455)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	747	Target Neighborhood Hits	223	Shared Neighborhood Hits	107
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CU081_HUMAN
NC score	0.079898 (rank : 456)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	747	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

WASF2_MOUSE
NC score	0.078934 (rank : 457)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	747	Target Neighborhood Hits	315	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CIZ1_HUMAN
NC score	0.078659 (rank : 458)	θ value	0.00665767 (rank : 302)
Query Neighborhood Hits	747	Target Neighborhood Hits	359	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

TRPC5_MOUSE
NC score	0.078619 (rank : 459)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	747	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

PI5PA_HUMAN
NC score	0.077881 (rank : 460)	θ value	1.06291 (rank : 511)
Query Neighborhood Hits	747	Target Neighborhood Hits	749	Shared Neighborhood Hits	169
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CSF1_HUMAN
NC score	0.077814 (rank : 461)	θ value	0.000786445 (rank : 276)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	70
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

RP1L1_HUMAN
NC score	0.077758 (rank : 462)	θ value	0.365318 (rank : 430)
Query Neighborhood Hits	747	Target Neighborhood Hits	1072	Shared Neighborhood Hits	177
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TRPC5_HUMAN
NC score	0.077124 (rank : 463)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	747	Target Neighborhood Hits	122	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

PCQAP_HUMAN
NC score	0.076749 (rank : 464)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	747	Target Neighborhood Hits	549	Shared Neighborhood Hits	131
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

EP300_HUMAN
NC score	0.076664 (rank : 465)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	747	Target Neighborhood Hits	821	Shared Neighborhood Hits	205
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

TB182_HUMAN
NC score	0.076352 (rank : 466)	θ value	1.06291 (rank : 521)
Query Neighborhood Hits	747	Target Neighborhood Hits	414	Shared Neighborhood Hits	122
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

FMN2_HUMAN
NC score	0.075851 (rank : 467)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	747	Target Neighborhood Hits	484	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

S23IP_MOUSE
NC score	0.075583 (rank : 468)	θ value	2.36792 (rank : 579)
Query Neighborhood Hits	747	Target Neighborhood Hits	363	Shared Neighborhood Hits	100
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

BAT3_MOUSE
NC score	0.075422 (rank : 469)	θ value	8.99809 (rank : 704)
Query Neighborhood Hits	747	Target Neighborhood Hits	518	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

PRR13_MOUSE
NC score	0.075122 (rank : 470)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ARI1A_HUMAN
NC score	0.075053 (rank : 471)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	747	Target Neighborhood Hits	787	Shared Neighborhood Hits	169
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TARA_HUMAN
NC score	0.075049 (rank : 472)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	747	Target Neighborhood Hits	1626	Shared Neighborhood Hits	214
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGON2_HUMAN
NC score	0.074915 (rank : 473)	θ value	0.813845 (rank : 490)
Query Neighborhood Hits	747	Target Neighborhood Hits	1037	Shared Neighborhood Hits	153
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CIC_MOUSE
NC score	0.074911 (rank : 474)	θ value	5.27518 (rank : 643)
Query Neighborhood Hits	747	Target Neighborhood Hits	742	Shared Neighborhood Hits	193
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SLY_MOUSE
NC score	0.074325 (rank : 475)	θ value	5.27518 (rank : 659)
Query Neighborhood Hits	747	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

CCNK_MOUSE
NC score	0.074225 (rank : 476)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	127
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

DIDO1_HUMAN
NC score	0.074224 (rank : 477)	θ value	0.00509761 (rank : 300)
Query Neighborhood Hits	747	Target Neighborhood Hits	960	Shared Neighborhood Hits	170
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SAMN1_HUMAN
NC score	0.074002 (rank : 478)	θ value	2.36792 (rank : 580)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SFR15_HUMAN
NC score	0.073570 (rank : 479)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	747	Target Neighborhood Hits	368	Shared Neighborhood Hits	114
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

LCP2_HUMAN
NC score	0.073523 (rank : 480)	θ value	0.0252991 (rank : 339)
Query Neighborhood Hits	747	Target Neighborhood Hits	531	Shared Neighborhood Hits	96
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

RTP3_MOUSE
NC score	0.073307 (rank : 481)	θ value	1.06291 (rank : 515)
Query Neighborhood Hits	747	Target Neighborhood Hits	374	Shared Neighborhood Hits	86
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TRPC4_MOUSE
NC score	0.073191 (rank : 482)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	747	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.073149 (rank : 483)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	747	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

OGFR_MOUSE
NC score	0.073139 (rank : 484)	θ value	0.0330416 (rank : 354)
Query Neighborhood Hits	747	Target Neighborhood Hits	584	Shared Neighborhood Hits	90
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PELP1_MOUSE
NC score	0.072539 (rank : 485)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	747	Target Neighborhood Hits	709	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SAMN1_MOUSE
NC score	0.072449 (rank : 486)	θ value	6.88961 (rank : 691)
Query Neighborhood Hits	747	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

DGKK_HUMAN
NC score	0.072175 (rank : 487)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	747	Target Neighborhood Hits	378	Shared Neighborhood Hits	139
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

FYB_HUMAN
NC score	0.072049 (rank : 488)	θ value	0.813845 (rank : 478)
Query Neighborhood Hits	747	Target Neighborhood Hits	379	Shared Neighborhood Hits	98
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

ACK1_MOUSE
NC score	0.071955 (rank : 489)	θ value	0.813845 (rank : 467)
Query Neighborhood Hits	747	Target Neighborhood Hits	1080	Shared Neighborhood Hits	160
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CDN1C_HUMAN
NC score	0.071788 (rank : 490)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	747	Target Neighborhood Hits	168	Shared Neighborhood Hits	74
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

M3K11_HUMAN
NC score	0.071174 (rank : 491)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	747	Target Neighborhood Hits	1136	Shared Neighborhood Hits	172
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

LIPB2_MOUSE
NC score	0.071043 (rank : 492)	θ value	0.0113563 (rank : 321)
Query Neighborhood Hits	747	Target Neighborhood Hits	570	Shared Neighborhood Hits	58
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

SYNJ1_HUMAN
NC score	0.070986 (rank : 493)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	747	Target Neighborhood Hits	498	Shared Neighborhood Hits	164
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SNPC4_HUMAN
NC score	0.070917 (rank : 494)	θ value	0.00175202 (rank : 288)
Query Neighborhood Hits	747	Target Neighborhood Hits	589	Shared Neighborhood Hits	117
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

ACK1_HUMAN
NC score	0.070759 (rank : 495)	θ value	2.36792 (rank : 555)
Query Neighborhood Hits	747	Target Neighborhood Hits	1140	Shared Neighborhood Hits	173
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CTDP1_HUMAN
NC score	0.070691 (rank : 496)	θ value	0.0736092 (rank : 377)
Query Neighborhood Hits	747	Target Neighborhood Hits	416	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

NCOR2_HUMAN
NC score	0.070639 (rank : 497)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	747	Target Neighborhood Hits	870	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

HRX_HUMAN
NC score	0.070432 (rank : 498)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	747	Target Neighborhood Hits	825	Shared Neighborhood Hits	144
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

K1543_HUMAN
NC score	0.070337 (rank : 499)	θ value	4.03905 (rank : 622)
Query Neighborhood Hits	747	Target Neighborhood Hits	435	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LIPB2_HUMAN
NC score	0.070300 (rank : 500)	θ value	0.00665767 (rank : 304)
Query Neighborhood Hits	747	Target Neighborhood Hits	599	Shared Neighborhood Hits	48
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

TMAP1_HUMAN
NC score	0.069840 (rank : 501)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	747	Target Neighborhood Hits	140	Shared Neighborhood Hits	72
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

MINT_MOUSE
NC score	0.069805 (rank : 502)	θ value	0.0252991 (rank : 340)
Query Neighborhood Hits	747	Target Neighborhood Hits	1514	Shared Neighborhood Hits	206
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CNKR2_MOUSE
NC score	0.069791 (rank : 503)	θ value	0.0330416 (rank : 347)
Query Neighborhood Hits	747	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

RIPK2_HUMAN
NC score	0.069770 (rank : 504)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	747	Target Neighborhood Hits	774	Shared Neighborhood Hits	61
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

CNKR2_HUMAN
NC score	0.069729 (rank : 505)	θ value	0.0330416 (rank : 346)
Query Neighborhood Hits	747	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

STAM1_MOUSE
NC score	0.069693 (rank : 506)	θ value	0.0252991 (rank : 342)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

BAT3_HUMAN
NC score	0.069691 (rank : 507)	θ value	1.06291 (rank : 495)
Query Neighborhood Hits	747	Target Neighborhood Hits	490	Shared Neighborhood Hits	121
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

PO121_HUMAN
NC score	0.069482 (rank : 508)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	747	Target Neighborhood Hits	344	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

TAU_HUMAN
NC score	0.069468 (rank : 509)	θ value	4.03905 (rank : 637)
Query Neighborhood Hits	747	Target Neighborhood Hits	448	Shared Neighborhood Hits	126
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TROAP_HUMAN
NC score	0.069158 (rank : 510)	θ value	0.0961366 (rank : 385)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	65
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

PELP1_HUMAN
NC score	0.069139 (rank : 511)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	747	Target Neighborhood Hits	596	Shared Neighborhood Hits	133
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SLY_HUMAN
NC score	0.069037 (rank : 512)	θ value	5.27518 (rank : 658)
Query Neighborhood Hits	747	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

PRR8_HUMAN
NC score	0.068831 (rank : 513)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	747	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

STAC_MOUSE
NC score	0.068805 (rank : 514)	θ value	0.0252991 (rank : 341)
Query Neighborhood Hits	747	Target Neighborhood Hits	268	Shared Neighborhood Hits	59
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
NC score	0.068730 (rank : 515)	θ value	0.0148317 (rank : 328)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

IWS1_MOUSE
NC score	0.068389 (rank : 516)	θ value	0.279714 (rank : 417)
Query Neighborhood Hits	747	Target Neighborhood Hits	1258	Shared Neighborhood Hits	151
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DGKH_HUMAN
NC score	0.068271 (rank : 517)	θ value	1.81305 (rank : 543)
Query Neighborhood Hits	747	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

STAC_HUMAN
NC score	0.068242 (rank : 518)	θ value	0.0193708 (rank : 336)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	58
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

PI5PA_MOUSE
NC score	0.068099 (rank : 519)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	747	Target Neighborhood Hits	331	Shared Neighborhood Hits	119
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CS007_HUMAN
NC score	0.068060 (rank : 520)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	747	Target Neighborhood Hits	401	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

TAU_MOUSE
NC score	0.067931 (rank : 521)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	747	Target Neighborhood Hits	502	Shared Neighborhood Hits	119
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

K1802_HUMAN
NC score	0.067835 (rank : 522)	θ value	4.03905 (rank : 623)
Query Neighborhood Hits	747	Target Neighborhood Hits	1378	Shared Neighborhood Hits	196
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PO121_MOUSE
NC score	0.067749 (rank : 523)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	747	Target Neighborhood Hits	345	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RPB1_MOUSE
NC score	0.067734 (rank : 524)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	747	Target Neighborhood Hits	363	Shared Neighborhood Hits	113
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.067461 (rank : 525)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	747	Target Neighborhood Hits	362	Shared Neighborhood Hits	112
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

MISS_MOUSE
NC score	0.067416 (rank : 526)	θ value	5.27518 (rank : 654)
Query Neighborhood Hits	747	Target Neighborhood Hits	444	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

RGS3_HUMAN
NC score	0.067261 (rank : 527)	θ value	0.0193708 (rank : 334)
Query Neighborhood Hits	747	Target Neighborhood Hits	1375	Shared Neighborhood Hits	187
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MILK1_MOUSE
NC score	0.066905 (rank : 528)	θ value	8.99809 (rank : 722)
Query Neighborhood Hits	747	Target Neighborhood Hits	788	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

T22D2_HUMAN
NC score	0.066854 (rank : 529)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	747	Target Neighborhood Hits	250	Shared Neighborhood Hits	88
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SF01_HUMAN
NC score	0.066794 (rank : 530)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	747	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

MLKL_HUMAN
NC score	0.066374 (rank : 531)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	747	Target Neighborhood Hits	600	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

3BP1_HUMAN
NC score	0.065899 (rank : 532)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	747	Target Neighborhood Hits	376	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

SMAP1_MOUSE
NC score	0.065844 (rank : 533)	θ value	8.99809 (rank : 734)
Query Neighborhood Hits	747	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

WNK2_HUMAN
NC score	0.065777 (rank : 534)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	747	Target Neighborhood Hits	1407	Shared Neighborhood Hits	238
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SGIP1_MOUSE
NC score	0.065600 (rank : 535)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	747	Target Neighborhood Hits	180	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TNK1_HUMAN
NC score	0.065246 (rank : 536)	θ value	0.47712 (rank : 450)
Query Neighborhood Hits	747	Target Neighborhood Hits	815	Shared Neighborhood Hits	77
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

BCAR1_HUMAN
NC score	0.065154 (rank : 537)	θ value	1.38821 (rank : 524)
Query Neighborhood Hits	747	Target Neighborhood Hits	554	Shared Neighborhood Hits	118
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

COIA1_HUMAN
NC score	0.064629 (rank : 538)	θ value	0.21417 (rank : 407)
Query Neighborhood Hits	747	Target Neighborhood Hits	447	Shared Neighborhood Hits	138
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MADCA_HUMAN
NC score	0.064598 (rank : 539)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	747	Target Neighborhood Hits	221	Shared Neighborhood Hits	89
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

AFF1_HUMAN
NC score	0.064321 (rank : 540)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	747	Target Neighborhood Hits	506	Shared Neighborhood Hits	105
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BRD4_MOUSE
NC score	0.064248 (rank : 541)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	747	Target Neighborhood Hits	845	Shared Neighborhood Hits	178
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CO4A5_HUMAN
NC score	0.064143 (rank : 542)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	747	Target Neighborhood Hits	383	Shared Neighborhood Hits	125
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

RIPK2_MOUSE
NC score	0.064015 (rank : 543)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	747	Target Neighborhood Hits	776	Shared Neighborhood Hits	59
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

M3K10_HUMAN
NC score	0.063850 (rank : 544)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	747	Target Neighborhood Hits	1071	Shared Neighborhood Hits	122
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

ABL1_MOUSE
NC score	0.063765 (rank : 545)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	747	Target Neighborhood Hits	1178	Shared Neighborhood Hits	161
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BAG3_MOUSE
NC score	0.063569 (rank : 546)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	747	Target Neighborhood Hits	513	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CRTC1_HUMAN
NC score	0.063547 (rank : 547)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	747	Target Neighborhood Hits	319	Shared Neighborhood Hits	105
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

WASF1_MOUSE
NC score	0.063379 (rank : 548)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	747	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

SAPS1_HUMAN
NC score	0.063272 (rank : 549)	θ value	0.0330416 (rank : 356)
Query Neighborhood Hits	747	Target Neighborhood Hits	704	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TIE1_MOUSE
NC score	0.063193 (rank : 550)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	747	Target Neighborhood Hits	1266	Shared Neighborhood Hits	83
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SYP2L_HUMAN
NC score	0.063138 (rank : 551)	θ value	0.47712 (rank : 447)
Query Neighborhood Hits	747	Target Neighborhood Hits	400	Shared Neighborhood Hits	127
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

FGR_MOUSE
NC score	0.063128 (rank : 552)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	747	Target Neighborhood Hits	1069	Shared Neighborhood Hits	105
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FYN_MOUSE
NC score	0.063116 (rank : 553)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	747	Target Neighborhood Hits	1073	Shared Neighborhood Hits	109
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

MINT_HUMAN
NC score	0.063028 (rank : 554)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	747	Target Neighborhood Hits	1291	Shared Neighborhood Hits	167
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TIE1_HUMAN
NC score	0.062934 (rank : 555)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	747	Target Neighborhood Hits	1241	Shared Neighborhood Hits	82
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

WASF2_HUMAN
NC score	0.062915 (rank : 556)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	747	Target Neighborhood Hits	280	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

SYNJ1_MOUSE
NC score	0.062809 (rank : 557)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	747	Target Neighborhood Hits	516	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CO1A1_MOUSE
NC score	0.062791 (rank : 558)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	747	Target Neighborhood Hits	457	Shared Neighborhood Hits	145
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

YES_HUMAN
NC score	0.062686 (rank : 559)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	747	Target Neighborhood Hits	1059	Shared Neighborhood Hits	106
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

FYN_HUMAN
NC score	0.062659 (rank : 560)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	747	Target Neighborhood Hits	1078	Shared Neighborhood Hits	111
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

TARA_MOUSE
NC score	0.062609 (rank : 561)	θ value	0.21417 (rank : 410)
Query Neighborhood Hits	747	Target Neighborhood Hits	1133	Shared Neighborhood Hits	149
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

M3K9_HUMAN
NC score	0.062587 (rank : 562)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	747	Target Neighborhood Hits	1123	Shared Neighborhood Hits	138
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

ABL1_HUMAN
NC score	0.062581 (rank : 563)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	747	Target Neighborhood Hits	1220	Shared Neighborhood Hits	159
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FGR_HUMAN
NC score	0.062571 (rank : 564)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	747	Target Neighborhood Hits	1067	Shared Neighborhood Hits	110
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

YES_MOUSE
NC score	0.062481 (rank : 565)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	747	Target Neighborhood Hits	1052	Shared Neighborhood Hits	103
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CITE4_HUMAN
NC score	0.062446 (rank : 566)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	747	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

TIE2_HUMAN
NC score	0.062414 (rank : 567)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	747	Target Neighborhood Hits	1192	Shared Neighborhood Hits	80
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ZN385_HUMAN
NC score	0.062394 (rank : 568)	θ value	0.0961366 (rank : 386)
Query Neighborhood Hits	747	Target Neighborhood Hits	614	Shared Neighborhood Hits	108
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

TIE2_MOUSE
NC score	0.062339 (rank : 569)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	747	Target Neighborhood Hits	1204	Shared Neighborhood Hits	78
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TXK_MOUSE
NC score	0.062225 (rank : 570)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	747	Target Neighborhood Hits	980	Shared Neighborhood Hits	94
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

CNOT3_HUMAN
NC score	0.062224 (rank : 571)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	747	Target Neighborhood Hits	425	Shared Neighborhood Hits	112
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

WASF1_HUMAN
NC score	0.062087 (rank : 572)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	115
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CO3A1_HUMAN
NC score	0.062059 (rank : 573)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	747	Target Neighborhood Hits	452	Shared Neighborhood Hits	151
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

TXK_HUMAN
NC score	0.062054 (rank : 574)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	747	Target Neighborhood Hits	971	Shared Neighborhood Hits	90
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

M3KL4_HUMAN
NC score	0.062027 (rank : 575)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	747	Target Neighborhood Hits	1087	Shared Neighborhood Hits	115
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

IRAK3_HUMAN
NC score	0.061926 (rank : 576)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	747	Target Neighborhood Hits	644	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

SMAP1_HUMAN
NC score	0.061874 (rank : 577)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	747	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

WASF4_HUMAN
NC score	0.061508 (rank : 578)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

FRK_HUMAN
NC score	0.061362 (rank : 579)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	747	Target Neighborhood Hits	1058	Shared Neighborhood Hits	102
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

CO3A1_MOUSE
NC score	0.061319 (rank : 580)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	747	Target Neighborhood Hits	466	Shared Neighborhood Hits	150
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

BTK_HUMAN
NC score	0.061204 (rank : 581)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	747	Target Neighborhood Hits	1026	Shared Neighborhood Hits	99
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

SGIP1_HUMAN
NC score	0.061170 (rank : 582)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	747	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MILK1_HUMAN
NC score	0.061114 (rank : 583)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	747	Target Neighborhood Hits	427	Shared Neighborhood Hits	134
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRC_HUMAN
NC score	0.061111 (rank : 584)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	747	Target Neighborhood Hits	1058	Shared Neighborhood Hits	106
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

ERBB4_HUMAN
NC score	0.061103 (rank : 585)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	747	Target Neighborhood Hits	910	Shared Neighborhood Hits	72
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

HCK_MOUSE
NC score	0.061035 (rank : 586)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	747	Target Neighborhood Hits	1029	Shared Neighborhood Hits	102
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

SELV_HUMAN
NC score	0.061017 (rank : 587)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	747	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

CNOT3_MOUSE
NC score	0.060866 (rank : 588)	θ value	8.99809 (rank : 708)
Query Neighborhood Hits	747	Target Neighborhood Hits	504	Shared Neighborhood Hits	109
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

TEC_HUMAN
NC score	0.060755 (rank : 589)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	747	Target Neighborhood Hits	1006	Shared Neighborhood Hits	97
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

BTK_MOUSE
NC score	0.060755 (rank : 590)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	747	Target Neighborhood Hits	1017	Shared Neighborhood Hits	99
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

MUC5B_HUMAN
NC score	0.060749 (rank : 591)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	747	Target Neighborhood Hits	1020	Shared Neighborhood Hits	142
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SMP1L_HUMAN
NC score	0.060730 (rank : 592)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.060667 (rank : 593)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	747	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

HCK_HUMAN
NC score	0.060643 (rank : 594)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	747	Target Neighborhood Hits	1035	Shared Neighborhood Hits	104
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

IRAK3_MOUSE
NC score	0.060610 (rank : 595)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	747	Target Neighborhood Hits	628	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

TCGAP_MOUSE
NC score	0.060522 (rank : 596)	θ value	6.88961 (rank : 696)
Query Neighborhood Hits	747	Target Neighborhood Hits	409	Shared Neighborhood Hits	120
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TNK1_MOUSE
NC score	0.060449 (rank : 597)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	747	Target Neighborhood Hits	806	Shared Neighborhood Hits	65
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

ZAP70_HUMAN
NC score	0.060405 (rank : 598)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	747	Target Neighborhood Hits	893	Shared Neighborhood Hits	74
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

SRC_MOUSE
NC score	0.060343 (rank : 599)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	747	Target Neighborhood Hits	1033	Shared Neighborhood Hits	101
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

LAD1_HUMAN
NC score	0.060340 (rank : 600)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	747	Target Neighborhood Hits	441	Shared Neighborhood Hits	77
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

FER_HUMAN
NC score	0.060309 (rank : 601)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	747	Target Neighborhood Hits	1278	Shared Neighborhood Hits	97
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FAK2_HUMAN
NC score	0.060201 (rank : 602)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	747	Target Neighborhood Hits	847	Shared Neighborhood Hits	63
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

K0310_HUMAN
NC score	0.060004 (rank : 603)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	747	Target Neighborhood Hits	420	Shared Neighborhood Hits	105
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LCK_MOUSE
NC score	0.059943 (rank : 604)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	747	Target Neighborhood Hits	981	Shared Neighborhood Hits	91
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

CO1A1_HUMAN
NC score	0.059858 (rank : 605)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	747	Target Neighborhood Hits	475	Shared Neighborhood Hits	142
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

FAK2_MOUSE
NC score	0.059794 (rank : 606)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	747	Target Neighborhood Hits	851	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

ERBB2_HUMAN
NC score	0.059794 (rank : 607)	θ value	5.27518 (rank : 648)
Query Neighborhood Hits	747	Target Neighborhood Hits	1073	Shared Neighborhood Hits	81
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

NCOR2_MOUSE
NC score	0.059741 (rank : 608)	θ value	4.03905 (rank : 630)
Query Neighborhood Hits	747	Target Neighborhood Hits	790	Shared Neighborhood Hits	140
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

ERBB2_MOUSE
NC score	0.059722 (rank : 609)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	747	Target Neighborhood Hits	918	Shared Neighborhood Hits	72
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

TEC_MOUSE
NC score	0.059698 (rank : 610)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	747	Target Neighborhood Hits	1006	Shared Neighborhood Hits	95
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

IRAK1_HUMAN
NC score	0.059641 (rank : 611)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	747	Target Neighborhood Hits	820	Shared Neighborhood Hits	89
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

PHLB1_HUMAN
NC score	0.059544 (rank : 612)	θ value	0.0330416 (rank : 355)
Query Neighborhood Hits	747	Target Neighborhood Hits	1038	Shared Neighborhood Hits	126
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

LCK_HUMAN
NC score	0.059522 (rank : 613)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	747	Target Neighborhood Hits	987	Shared Neighborhood Hits	93
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

ITK_HUMAN
NC score	0.059497 (rank : 614)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	747	Target Neighborhood Hits	1016	Shared Neighborhood Hits	94
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ZAP70_MOUSE
NC score	0.059485 (rank : 615)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	747	Target Neighborhood Hits	905	Shared Neighborhood Hits	73
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

IWS1_HUMAN
NC score	0.059474 (rank : 616)	θ value	0.813845 (rank : 481)
Query Neighborhood Hits	747	Target Neighborhood Hits	1241	Shared Neighborhood Hits	136
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MLKL_MOUSE
NC score	0.059415 (rank : 617)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	747	Target Neighborhood Hits	707	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

FAK1_HUMAN
NC score	0.059395 (rank : 618)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	747	Target Neighborhood Hits	850	Shared Neighborhood Hits	66
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

VASP_MOUSE
NC score	0.059340 (rank : 619)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	747	Target Neighborhood Hits	195	Shared Neighborhood Hits	76
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

PTK6_MOUSE
NC score	0.059289 (rank : 620)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	747	Target Neighborhood Hits	1026	Shared Neighborhood Hits	104
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

SMR1_MOUSE
NC score	0.059240 (rank : 621)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	747	Target Neighborhood Hits	103	Shared Neighborhood Hits	53
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

FAK1_MOUSE
NC score	0.059175 (rank : 622)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	747	Target Neighborhood Hits	850	Shared Neighborhood Hits	65
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

TRPC1_HUMAN
NC score	0.059127 (rank : 623)	θ value	6.88961 (rank : 698)
Query Neighborhood Hits	747	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

BCAR1_MOUSE
NC score	0.059085 (rank : 624)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	747	Target Neighborhood Hits	438	Shared Neighborhood Hits	105
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PTK6_HUMAN
NC score	0.059078 (rank : 625)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	747	Target Neighborhood Hits	1020	Shared Neighborhood Hits	104
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

ITK_MOUSE
NC score	0.058976 (rank : 626)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	747	Target Neighborhood Hits	985	Shared Neighborhood Hits	91
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

WBS14_HUMAN
NC score	0.058941 (rank : 627)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

DDR1_MOUSE
NC score	0.058920 (rank : 628)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	747	Target Neighborhood Hits	818	Shared Neighborhood Hits	65
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR1_HUMAN
NC score	0.058888 (rank : 629)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	747	Target Neighborhood Hits	819	Shared Neighborhood Hits	65
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

WASP_HUMAN
NC score	0.058847 (rank : 630)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	747	Target Neighborhood Hits	195	Shared Neighborhood Hits	98
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

GUC2G_MOUSE
NC score	0.058793 (rank : 631)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	747	Target Neighborhood Hits	644	Shared Neighborhood Hits	53
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

ROR2_MOUSE
NC score	0.058729 (rank : 632)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	747	Target Neighborhood Hits	1000	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

RIPK3_HUMAN
NC score	0.058714 (rank : 633)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	747	Target Neighborhood Hits	828	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

LYN_MOUSE
NC score	0.058713 (rank : 634)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	747	Target Neighborhood Hits	1023	Shared Neighborhood Hits	102
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

DMRTD_HUMAN
NC score	0.058708 (rank : 635)	θ value	0.0330416 (rank : 349)
Query Neighborhood Hits	747	Target Neighborhood Hits	216	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

LYN_HUMAN
NC score	0.058566 (rank : 636)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	747	Target Neighborhood Hits	1022	Shared Neighborhood Hits	99
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

AATK_MOUSE
NC score	0.058557 (rank : 637)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	747	Target Neighborhood Hits	942	Shared Neighborhood Hits	123
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

BLK_HUMAN
NC score	0.058514 (rank : 638)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	747	Target Neighborhood Hits	994	Shared Neighborhood Hits	94
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ATX2L_HUMAN
NC score	0.058475 (rank : 639)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	747	Target Neighborhood Hits	443	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

LIPB1_HUMAN
NC score	0.058445 (rank : 640)	θ value	0.365318 (rank : 428)
Query Neighborhood Hits	747	Target Neighborhood Hits	640	Shared Neighborhood Hits	61
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LTK_HUMAN
NC score	0.058424 (rank : 641)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	747	Target Neighborhood Hits	774	Shared Neighborhood Hits	62
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

COHA1_HUMAN
NC score	0.058415 (rank : 642)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	747	Target Neighborhood Hits	400	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

KI67_HUMAN
NC score	0.058284 (rank : 643)	θ value	4.03905 (rank : 624)
Query Neighborhood Hits	747	Target Neighborhood Hits	581	Shared Neighborhood Hits	85
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

AATK_HUMAN
NC score	0.058161 (rank : 644)	θ value	1.06291 (rank : 492)
Query Neighborhood Hits	747	Target Neighborhood Hits	1243	Shared Neighborhood Hits	149
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

INSR_HUMAN
NC score	0.058131 (rank : 645)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	747	Target Neighborhood Hits	963	Shared Neighborhood Hits	69
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

EGFR_HUMAN
NC score	0.058095 (rank : 646)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	747	Target Neighborhood Hits	939	Shared Neighborhood Hits	64
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ROR1_HUMAN
NC score	0.058071 (rank : 647)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	747	Target Neighborhood Hits	1018	Shared Neighborhood Hits	66
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

RIPK3_MOUSE
NC score	0.058031 (rank : 648)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	747	Target Neighborhood Hits	867	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

EGFR_MOUSE
NC score	0.057962 (rank : 649)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	747	Target Neighborhood Hits	927	Shared Neighborhood Hits	65
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

CENA1_HUMAN
NC score	0.057944 (rank : 650)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	747	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

LTK_MOUSE
NC score	0.057925 (rank : 651)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	747	Target Neighborhood Hits	770	Shared Neighborhood Hits	61
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

ROR1_MOUSE
NC score	0.057847 (rank : 652)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	747	Target Neighborhood Hits	1025	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

INSRR_MOUSE
NC score	0.057840 (rank : 653)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	747	Target Neighborhood Hits	961	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IRAK2_HUMAN
NC score	0.057757 (rank : 654)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	747	Target Neighborhood Hits	714	Shared Neighborhood Hits	59
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

ROR2_HUMAN
NC score	0.057698 (rank : 655)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	747	Target Neighborhood Hits	1014	Shared Neighborhood Hits	66
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

LARP4_MOUSE
NC score	0.057681 (rank : 656)	θ value	1.06291 (rank : 507)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

TRDN_HUMAN
NC score	0.057629 (rank : 657)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	747	Target Neighborhood Hits	542	Shared Neighborhood Hits	48
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

BLK_MOUSE
NC score	0.057588 (rank : 658)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	747	Target Neighborhood Hits	992	Shared Neighborhood Hits	90
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

MET_HUMAN
NC score	0.057545 (rank : 659)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	747	Target Neighborhood Hits	831	Shared Neighborhood Hits	62
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

KSYK_MOUSE
NC score	0.057543 (rank : 660)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	747	Target Neighborhood Hits	944	Shared Neighborhood Hits	78
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

DIAP1_HUMAN
NC score	0.057536 (rank : 661)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	747	Target Neighborhood Hits	784	Shared Neighborhood Hits	153
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

SPT5H_HUMAN
NC score	0.057531 (rank : 662)	θ value	1.06291 (rank : 518)
Query Neighborhood Hits	747	Target Neighborhood Hits	436	Shared Neighborhood Hits	103
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

INSRR_HUMAN
NC score	0.057481 (rank : 663)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	747	Target Neighborhood Hits	950	Shared Neighborhood Hits	72
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

MET_MOUSE
NC score	0.057402 (rank : 664)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	747	Target Neighborhood Hits	844	Shared Neighborhood Hits	64
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RYK_HUMAN
NC score	0.057379 (rank : 665)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	747	Target Neighborhood Hits	701	Shared Neighborhood Hits	55
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

MATK_HUMAN
NC score	0.057280 (rank : 666)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	747	Target Neighborhood Hits	954	Shared Neighborhood Hits	80
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

INSR_MOUSE
NC score	0.057270 (rank : 667)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	747	Target Neighborhood Hits	968	Shared Neighborhood Hits	67
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

CI079_HUMAN
NC score	0.057262 (rank : 668)	θ value	0.125558 (rank : 390)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

ABL2_HUMAN
NC score	0.057214 (rank : 669)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	747	Target Neighborhood Hits	1045	Shared Neighborhood Hits	100
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

MATK_MOUSE
NC score	0.057199 (rank : 670)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	747	Target Neighborhood Hits	952	Shared Neighborhood Hits	80
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

SPT5H_MOUSE
NC score	0.057176 (rank : 671)	θ value	1.06291 (rank : 519)
Query Neighborhood Hits	747	Target Neighborhood Hits	437	Shared Neighborhood Hits	103
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

DDR2_HUMAN
NC score	0.057081 (rank : 672)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	747	Target Neighborhood Hits	818	Shared Neighborhood Hits	60
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

KSYK_HUMAN
NC score	0.057037 (rank : 673)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	747	Target Neighborhood Hits	901	Shared Neighborhood Hits	72
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MTSS1_MOUSE
NC score	0.056968 (rank : 674)	θ value	0.125558 (rank : 391)
Query Neighborhood Hits	747	Target Neighborhood Hits	592	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CSK_HUMAN
NC score	0.056871 (rank : 675)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	89
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

STAM2_MOUSE
NC score	0.056859 (rank : 676)	θ value	0.62314 (rank : 460)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	55
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

CO039_HUMAN
NC score	0.056762 (rank : 677)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MAST4_HUMAN
NC score	0.056754 (rank : 678)	θ value	1.69304e-06 (rank : 189)
Query Neighborhood Hits	747	Target Neighborhood Hits	1804	Shared Neighborhood Hits	234
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RYK_MOUSE
NC score	0.056751 (rank : 679)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	747	Target Neighborhood Hits	715	Shared Neighborhood Hits	56
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

VASP_HUMAN
NC score	0.056738 (rank : 680)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	97
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

MERTK_HUMAN
NC score	0.056735 (rank : 681)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	747	Target Neighborhood Hits	988	Shared Neighborhood Hits	68
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

CASC3_MOUSE
NC score	0.056727 (rank : 682)	θ value	0.0330416 (rank : 345)
Query Neighborhood Hits	747	Target Neighborhood Hits	333	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

SH3K1_HUMAN
NC score	0.056681 (rank : 683)	θ value	8.99809 (rank : 732)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	76
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

MERTK_MOUSE
NC score	0.056622 (rank : 684)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	747	Target Neighborhood Hits	974	Shared Neighborhood Hits	65
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

ROS_HUMAN
NC score	0.056593 (rank : 685)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	747	Target Neighborhood Hits	907	Shared Neighborhood Hits	64
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

M3K7_MOUSE
NC score	0.056532 (rank : 686)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	747	Target Neighborhood Hits	892	Shared Neighborhood Hits	63
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

DIAP1_MOUSE
NC score	0.056513 (rank : 687)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	747	Target Neighborhood Hits	839	Shared Neighborhood Hits	142
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

M3K7_HUMAN
NC score	0.056506 (rank : 688)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	747	Target Neighborhood Hits	892	Shared Neighborhood Hits	63
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

ALK_MOUSE
NC score	0.056437 (rank : 689)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	747	Target Neighborhood Hits	811	Shared Neighborhood Hits	69
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

MAP4_MOUSE
NC score	0.056432 (rank : 690)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	747	Target Neighborhood Hits	409	Shared Neighborhood Hits	91
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CEND2_HUMAN
NC score	0.056430 (rank : 691)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	747	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

GUC2C_HUMAN
NC score	0.056412 (rank : 692)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	747	Target Neighborhood Hits	624	Shared Neighborhood Hits	58
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

UFO_MOUSE
NC score	0.056387 (rank : 693)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	747	Target Neighborhood Hits	988	Shared Neighborhood Hits	65
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

UFO_HUMAN
NC score	0.056382 (rank : 694)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	747	Target Neighborhood Hits	981	Shared Neighborhood Hits	70
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

PKHA6_MOUSE
NC score	0.056360 (rank : 695)	θ value	1.06291 (rank : 512)
Query Neighborhood Hits	747	Target Neighborhood Hits	591	Shared Neighborhood Hits	97
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

DDR2_MOUSE
NC score	0.056337 (rank : 696)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	747	Target Neighborhood Hits	813	Shared Neighborhood Hits	60
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

FES_MOUSE
NC score	0.056255 (rank : 697)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	747	Target Neighborhood Hits	980	Shared Neighborhood Hits	78
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

TYRO3_MOUSE
NC score	0.056129 (rank : 698)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	747	Target Neighborhood Hits	1007	Shared Neighborhood Hits	64
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

NTRK1_HUMAN
NC score	0.056048 (rank : 699)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	747	Target Neighborhood Hits	1023	Shared Neighborhood Hits	61
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

COGA1_HUMAN
NC score	0.056038 (rank : 700)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	747	Target Neighborhood Hits	345	Shared Neighborhood Hits	124
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

TCRG1_MOUSE
NC score	0.056028 (rank : 701)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	747	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

PCQAP_MOUSE
NC score	0.055946 (rank : 702)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	747	Target Neighborhood Hits	506	Shared Neighborhood Hits	124
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

BMX_MOUSE
NC score	0.055922 (rank : 703)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	747	Target Neighborhood Hits	912	Shared Neighborhood Hits	74
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

IGF1R_MOUSE
NC score	0.055897 (rank : 704)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	747	Target Neighborhood Hits	973	Shared Neighborhood Hits	67
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

TYRO3_HUMAN
NC score	0.055863 (rank : 705)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	747	Target Neighborhood Hits	995	Shared Neighborhood Hits	63
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

ARI1B_HUMAN
NC score	0.055841 (rank : 706)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	747	Target Neighborhood Hits	567	Shared Neighborhood Hits	144
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CO039_MOUSE
NC score	0.055747 (rank : 707)	θ value	6.88961 (rank : 673)
Query Neighborhood Hits	747	Target Neighborhood Hits	445	Shared Neighborhood Hits	112
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SRMS_MOUSE
NC score	0.055734 (rank : 708)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	747	Target Neighborhood Hits	964	Shared Neighborhood Hits	79
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

RON_MOUSE
NC score	0.055731 (rank : 709)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	747	Target Neighborhood Hits	836	Shared Neighborhood Hits	62
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SRMS_HUMAN
NC score	0.055728 (rank : 710)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	747	Target Neighborhood Hits	946	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

IGF1R_HUMAN
NC score	0.055705 (rank : 711)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	747	Target Neighborhood Hits	977	Shared Neighborhood Hits	68
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

CSK_MOUSE
NC score	0.055704 (rank : 712)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	747	Target Neighborhood Hits	1009	Shared Neighborhood Hits	89
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

ALK_HUMAN
NC score	0.055681 (rank : 713)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	747	Target Neighborhood Hits	795	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

BMX_HUMAN
NC score	0.055620 (rank : 714)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	747	Target Neighborhood Hits	942	Shared Neighborhood Hits	80
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

FES_HUMAN
NC score	0.055613 (rank : 715)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	747	Target Neighborhood Hits	978	Shared Neighborhood Hits	75
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

LIPB1_MOUSE
NC score	0.055504 (rank : 716)	θ value	0.62314 (rank : 455)
Query Neighborhood Hits	747	Target Neighborhood Hits	727	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

COHA1_MOUSE
NC score	0.055423 (rank : 717)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	747	Target Neighborhood Hits	414	Shared Neighborhood Hits	130
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

RON_HUMAN
NC score	0.055355 (rank : 718)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	747	Target Neighborhood Hits	842	Shared Neighborhood Hits	64
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

PDCD7_HUMAN
NC score	0.055304 (rank : 719)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	747	Target Neighborhood Hits	255	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

TRPC1_MOUSE
NC score	0.055288 (rank : 720)	θ value	3.0926 (rank : 605)
Query Neighborhood Hits	747	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

M3K12_HUMAN
NC score	0.055263 (rank : 721)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	747	Target Neighborhood Hits	940	Shared Neighborhood Hits	104
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

SPTA3_MOUSE
NC score	0.055086 (rank : 722)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

ABI2_HUMAN
NC score	0.055082 (rank : 723)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

STAM2_HUMAN
NC score	0.054979 (rank : 724)	θ value	0.365318 (rank : 431)
Query Neighborhood Hits	747	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

MLTK_HUMAN
NC score	0.054947 (rank : 725)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	747	Target Neighborhood Hits	911	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MBB1A_HUMAN
NC score	0.054871 (rank : 726)	θ value	0.813845 (rank : 483)
Query Neighborhood Hits	747	Target Neighborhood Hits	665	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PKHA6_HUMAN
NC score	0.054862 (rank : 727)	θ value	0.0563607 (rank : 369)
Query Neighborhood Hits	747	Target Neighborhood Hits	556	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SH3K1_MOUSE
NC score	0.054810 (rank : 728)	θ value	8.99809 (rank : 733)
Query Neighborhood Hits	747	Target Neighborhood Hits	332	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

MEGF9_MOUSE
NC score	0.054786 (rank : 729)	θ value	0.279714 (rank : 418)
Query Neighborhood Hits	747	Target Neighborhood Hits	896	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DOT1L_HUMAN
NC score	0.054775 (rank : 730)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	747	Target Neighborhood Hits	660	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

RET_MOUSE
NC score	0.054775 (rank : 731)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	747	Target Neighborhood Hits	884	Shared Neighborhood Hits	64
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

M3K12_MOUSE
NC score	0.054717 (rank : 732)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	747	Target Neighborhood Hits	957	Shared Neighborhood Hits	98
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

FA47A_HUMAN
NC score	0.054677 (rank : 733)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	747	Target Neighborhood Hits	451	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CO5A2_HUMAN
NC score	0.054675 (rank : 734)	θ value	0.0113563 (rank : 317)
Query Neighborhood Hits	747	Target Neighborhood Hits	760	Shared Neighborhood Hits	154
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

GRAP_HUMAN
NC score	0.054622 (rank : 735)	θ value	0.00175202 (rank : 287)
Query Neighborhood Hits	747	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

MLTK_MOUSE
NC score	0.054605 (rank : 736)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	747	Target Neighborhood Hits	874	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

RET_HUMAN
NC score	0.054590 (rank : 737)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	747	Target Neighborhood Hits	873	Shared Neighborhood Hits	61
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

ARFG1_MOUSE
NC score	0.054590 (rank : 738)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	747	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

TCRG1_HUMAN
NC score	0.054579 (rank : 739)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	747	Target Neighborhood Hits	929	Shared Neighborhood Hits	129
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

SC24C_HUMAN
NC score	0.054549 (rank : 740)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	747	Target Neighborhood Hits	662	Shared Neighborhood Hits	130
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARFG3_MOUSE
NC score	0.054285 (rank : 741)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	747	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

WASF3_MOUSE
NC score	0.054210 (rank : 742)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

RAF1_HUMAN
NC score	0.054156 (rank : 743)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	747	Target Neighborhood Hits	886	Shared Neighborhood Hits	67
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ERBB3_HUMAN
NC score	0.054129 (rank : 744)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	747	Target Neighborhood Hits	918	Shared Neighborhood Hits	69
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ARFG1_HUMAN
NC score	0.054118 (rank : 745)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	747	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

BRAF1_HUMAN
NC score	0.054083 (rank : 746)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	747	Target Neighborhood Hits	883	Shared Neighborhood Hits	68
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

RAF1_MOUSE
NC score	0.054047 (rank : 747)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	747	Target Neighborhood Hits	886	Shared Neighborhood Hits	66
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

WNK4_HUMAN
NC score	0.054003 (rank : 748)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	747	Target Neighborhood Hits	1043	Shared Neighborhood Hits	174
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

IRAK1_MOUSE
NC score	0.054001 (rank : 749)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	747	Target Neighborhood Hits	784	Shared Neighborhood Hits	72
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

ARFG3_HUMAN
NC score	0.053976 (rank : 750)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	747	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CENA2_MOUSE
NC score	0.053964 (rank : 751)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	747	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

SREC2_HUMAN
NC score	0.053827 (rank : 752)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	747	Target Neighborhood Hits	645	Shared Neighborhood Hits	117
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

VCX3_HUMAN
NC score	0.053759 (rank : 753)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	747	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

GUC2F_HUMAN
NC score	0.053524 (rank : 754)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	747	Target Neighborhood Hits	740	Shared Neighborhood Hits	56
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

AN13D_HUMAN
NC score	0.053512 (rank : 755)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	747	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

SF01_MOUSE
NC score	0.053466 (rank : 756)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	747	Target Neighborhood Hits	240	Shared Neighborhood Hits	93
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

MAP4_HUMAN
NC score	0.053461 (rank : 757)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	747	Target Neighborhood Hits	428	Shared Neighborhood Hits	89
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ERBB3_MOUSE
NC score	0.053434 (rank : 758)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	747	Target Neighborhood Hits	898	Shared Neighborhood Hits	68
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

SETD2_HUMAN
NC score	0.053368 (rank : 759)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	747	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HRBL_MOUSE
NC score	0.053315 (rank : 760)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	747	Target Neighborhood Hits	269	Shared Neighborhood Hits	62
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ANPRB_MOUSE
NC score	0.053268 (rank : 761)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	747	Target Neighborhood Hits	607	Shared Neighborhood Hits	51
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

NTRK3_HUMAN
NC score	0.053117 (rank : 762)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	747	Target Neighborhood Hits	1115	Shared Neighborhood Hits	64
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

AN13D_MOUSE
NC score	0.053111 (rank : 763)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	747	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

CENA2_HUMAN
NC score	0.052962 (rank : 764)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	747	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

ARAF_HUMAN
NC score	0.052776 (rank : 765)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	747	Target Neighborhood Hits	924	Shared Neighborhood Hits	77
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

NTRK2_HUMAN
NC score	0.052776 (rank : 766)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	747	Target Neighborhood Hits	1081	Shared Neighborhood Hits	64
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

ATX2_MOUSE
NC score	0.052664 (rank : 767)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	747	Target Neighborhood Hits	445	Shared Neighborhood Hits	108
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

K1683_HUMAN
NC score	0.052655 (rank : 768)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	747	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

NTRK2_MOUSE
NC score	0.052647 (rank : 769)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	747	Target Neighborhood Hits	1088	Shared Neighborhood Hits	64
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

SELPL_MOUSE
NC score	0.052622 (rank : 770)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	747	Target Neighborhood Hits	588	Shared Neighborhood Hits	115
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SSB4_HUMAN
NC score	0.052568 (rank : 771)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	747	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

CDAN1_HUMAN
NC score	0.052526 (rank : 772)	θ value	0.0736092 (rank : 376)
Query Neighborhood Hits	747	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

RIPK1_HUMAN
NC score	0.052441 (rank : 773)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	747	Target Neighborhood Hits	891	Shared Neighborhood Hits	69
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

FA47B_HUMAN
NC score	0.052368 (rank : 774)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	747	Target Neighborhood Hits	431	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

CEL_HUMAN
NC score	0.052214 (rank : 775)	θ value	0.0148317 (rank : 325)
Query Neighborhood Hits	747	Target Neighborhood Hits	896	Shared Neighborhood Hits	146
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BRD4_HUMAN
NC score	0.052156 (rank : 776)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	747	Target Neighborhood Hits	851	Shared Neighborhood Hits	179
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

ANPRB_HUMAN
NC score	0.052118 (rank : 777)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	747	Target Neighborhood Hits	646	Shared Neighborhood Hits	54
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

TESK2_HUMAN
NC score	0.052082 (rank : 778)	θ value	0.125558 (rank : 392)
Query Neighborhood Hits	747	Target Neighborhood Hits	851	Shared Neighborhood Hits	66
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

CO5A1_HUMAN
NC score	0.052003 (rank : 779)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	747	Target Neighborhood Hits	434	Shared Neighborhood Hits	141
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

MOS_HUMAN
NC score	0.051995 (rank : 780)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	747	Target Neighborhood Hits	829	Shared Neighborhood Hits	61
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MUSK_HUMAN
NC score	0.051915 (rank : 781)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	747	Target Neighborhood Hits	1074	Shared Neighborhood Hits	63
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

ARAF_MOUSE
NC score	0.051813 (rank : 782)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	747	Target Neighborhood Hits	874	Shared Neighborhood Hits	65
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

WASF3_HUMAN
NC score	0.051752 (rank : 783)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	747	Target Neighborhood Hits	204	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

RAI1_MOUSE
NC score	0.051747 (rank : 784)	θ value	1.06291 (rank : 514)
Query Neighborhood Hits	747	Target Neighborhood Hits	344	Shared Neighborhood Hits	84
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AFF1_MOUSE
NC score	0.051519 (rank : 785)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	747	Target Neighborhood Hits	351	Shared Neighborhood Hits	92
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

GUC2E_MOUSE
NC score	0.051433 (rank : 786)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	747	Target Neighborhood Hits	692	Shared Neighborhood Hits	57
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

FMN2_MOUSE
NC score	0.051393 (rank : 787)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MUSK_MOUSE
NC score	0.051257 (rank : 788)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	747	Target Neighborhood Hits	1057	Shared Neighborhood Hits	62
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

PSL1_HUMAN
NC score	0.051181 (rank : 789)	θ value	0.163984 (rank : 400)
Query Neighborhood Hits	747	Target Neighborhood Hits	650	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

AUTS2_HUMAN
NC score	0.051056 (rank : 790)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	747	Target Neighborhood Hits	342	Shared Neighborhood Hits	96
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

M3K13_HUMAN
NC score	0.051054 (rank : 791)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	747	Target Neighborhood Hits	911	Shared Neighborhood Hits	66
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

ENL_HUMAN
NC score	0.051001 (rank : 792)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ELN_HUMAN
NC score	0.050907 (rank : 793)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	747	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

BAG3_HUMAN
NC score	0.050882 (rank : 794)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	86
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

RIMB1_HUMAN
NC score	0.050824 (rank : 795)	θ value	8.99809 (rank : 726)
Query Neighborhood Hits	747	Target Neighborhood Hits	1479	Shared Neighborhood Hits	176
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PDC6I_MOUSE
NC score	0.050814 (rank : 796)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	747	Target Neighborhood Hits	275	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

KIT_HUMAN
NC score	0.050581 (rank : 797)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	747	Target Neighborhood Hits	953	Shared Neighborhood Hits	62
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

RIPK1_MOUSE
NC score	0.050574 (rank : 798)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	747	Target Neighborhood Hits	874	Shared Neighborhood Hits	67
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

CD2AP_MOUSE
NC score	0.050531 (rank : 799)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	747	Target Neighborhood Hits	336	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

ANPRA_MOUSE
NC score	0.050521 (rank : 800)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	747	Target Neighborhood Hits	600	Shared Neighborhood Hits	53
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

JAK1_HUMAN
NC score	0.050294 (rank : 801)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	747	Target Neighborhood Hits	858	Shared Neighborhood Hits	62
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

MAP1A_HUMAN
NC score	0.050274 (rank : 802)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	747	Target Neighborhood Hits	1626	Shared Neighborhood Hits	177
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MNT_HUMAN
NC score	0.050162 (rank : 803)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	747	Target Neighborhood Hits	496	Shared Neighborhood Hits	110
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

BAZ2A_MOUSE
NC score	0.050118 (rank : 804)	θ value	0.0193708 (rank : 329)
Query Neighborhood Hits	747	Target Neighborhood Hits	744	Shared Neighborhood Hits	117
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CT032_HUMAN
NC score	0.050103 (rank : 805)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	747	Target Neighborhood Hits	235	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

JAK1_MOUSE
NC score	0.050087 (rank : 806)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	747	Target Neighborhood Hits	854	Shared Neighborhood Hits	61
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

KIT_MOUSE
NC score	0.050059 (rank : 807)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	747	Target Neighborhood Hits	949	Shared Neighborhood Hits	64
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

NSD1_MOUSE
NC score	0.050020 (rank : 808)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	747	Target Neighborhood Hits	472	Shared Neighborhood Hits	80
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CO002_HUMAN
NC score	0.049960 (rank : 809)	θ value	2.36792 (rank : 559)
Query Neighborhood Hits	747	Target Neighborhood Hits	387	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO7A1_HUMAN
NC score	0.049871 (rank : 810)	θ value	0.0563607 (rank : 367)
Query Neighborhood Hits	747	Target Neighborhood Hits	807	Shared Neighborhood Hits	173
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

GRAP_MOUSE
NC score	0.049456 (rank : 811)	θ value	0.0563607 (rank : 368)
Query Neighborhood Hits	747	Target Neighborhood Hits	309	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ZIMP7_MOUSE
NC score	0.049183 (rank : 812)	θ value	0.62314 (rank : 465)
Query Neighborhood Hits	747	Target Neighborhood Hits	566	Shared Neighborhood Hits	112
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

RAI1_HUMAN
NC score	0.048781 (rank : 813)	θ value	2.36792 (rank : 577)
Query Neighborhood Hits	747	Target Neighborhood Hits	360	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ITSN1_MOUSE
NC score	0.048737 (rank : 814)	θ value	0.365318 (rank : 427)
Query Neighborhood Hits	747	Target Neighborhood Hits	1669	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NFRKB_MOUSE
NC score	0.048562 (rank : 815)	θ value	0.62314 (rank : 457)
Query Neighborhood Hits	747	Target Neighborhood Hits	393	Shared Neighborhood Hits	83
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ENAM_HUMAN
NC score	0.048328 (rank : 816)	θ value	0.00869519 (rank : 309)
Query Neighborhood Hits	747	Target Neighborhood Hits	227	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

JPH2_HUMAN
NC score	0.048323 (rank : 817)	θ value	0.0113563 (rank : 320)
Query Neighborhood Hits	747	Target Neighborhood Hits	639	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

DAB2_MOUSE
NC score	0.048076 (rank : 818)	θ value	6.88961 (rank : 678)
Query Neighborhood Hits	747	Target Neighborhood Hits	163	Shared Neighborhood Hits	51
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

SSBP4_HUMAN
NC score	0.048045 (rank : 819)	θ value	1.06291 (rank : 520)
Query Neighborhood Hits	747	Target Neighborhood Hits	753	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

IL4RA_MOUSE
NC score	0.047771 (rank : 820)	θ value	0.00869519 (rank : 310)
Query Neighborhood Hits	747	Target Neighborhood Hits	194	Shared Neighborhood Hits	39
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PDZD2_HUMAN
NC score	0.047766 (rank : 821)	θ value	0.0431538 (rank : 361)
Query Neighborhood Hits	747	Target Neighborhood Hits	772	Shared Neighborhood Hits	122
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

NSD1_HUMAN
NC score	0.047705 (rank : 822)	θ value	0.62314 (rank : 458)
Query Neighborhood Hits	747	Target Neighborhood Hits	427	Shared Neighborhood Hits	74
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TULP4_HUMAN
NC score	0.047193 (rank : 823)	θ value	0.125558 (rank : 394)
Query Neighborhood Hits	747	Target Neighborhood Hits	426	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MKL1_MOUSE
NC score	0.046967 (rank : 824)	θ value	4.03905 (rank : 627)
Query Neighborhood Hits	747	Target Neighborhood Hits	667	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

IF4G1_MOUSE
NC score	0.046928 (rank : 825)	θ value	8.99809 (rank : 717)
Query Neighborhood Hits	747	Target Neighborhood Hits	534	Shared Neighborhood Hits	111
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

ASTL_HUMAN
NC score	0.046847 (rank : 826)	θ value	0.00509761 (rank : 299)
Query Neighborhood Hits	747	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

CT174_HUMAN
NC score	0.046572 (rank : 827)	θ value	6.88961 (rank : 677)
Query Neighborhood Hits	747	Target Neighborhood Hits	181	Shared Neighborhood Hits	58
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

CD248_HUMAN
NC score	0.046036 (rank : 828)	θ value	8.99809 (rank : 706)
Query Neighborhood Hits	747	Target Neighborhood Hits	679	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

NPAS4_MOUSE
NC score	0.046027 (rank : 829)	θ value	0.00035302 (rank : 265)
Query Neighborhood Hits	747	Target Neighborhood Hits	245	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

ULK1_MOUSE
NC score	0.045877 (rank : 830)	θ value	0.0431538 (rank : 364)
Query Neighborhood Hits	747	Target Neighborhood Hits	1214	Shared Neighborhood Hits	135
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

COBA1_HUMAN
NC score	0.045807 (rank : 831)	θ value	1.06291 (rank : 499)
Query Neighborhood Hits	747	Target Neighborhood Hits	491	Shared Neighborhood Hits	124
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

MTSS1_HUMAN
NC score	0.045143 (rank : 832)	θ value	0.62314 (rank : 456)
Query Neighborhood Hits	747	Target Neighborhood Hits	504	Shared Neighborhood Hits	88
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

DAB1_HUMAN
NC score	0.045123 (rank : 833)	θ value	0.365318 (rank : 425)
Query Neighborhood Hits	747	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

ARMX2_MOUSE
NC score	0.044743 (rank : 834)	θ value	0.62314 (rank : 451)
Query Neighborhood Hits	747	Target Neighborhood Hits	349	Shared Neighborhood Hits	74
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

COBA1_MOUSE
NC score	0.044546 (rank : 835)	θ value	1.06291 (rank : 500)
Query Neighborhood Hits	747	Target Neighborhood Hits	487	Shared Neighborhood Hits	125
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

AMPH_HUMAN
NC score	0.044538 (rank : 836)	θ value	1.06291 (rank : 493)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	81
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

CECR2_HUMAN
NC score	0.044250 (rank : 837)	θ value	6.88961 (rank : 672)
Query Neighborhood Hits	747	Target Neighborhood Hits	543	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

EP400_MOUSE
NC score	0.044145 (rank : 838)	θ value	0.0961366 (rank : 383)
Query Neighborhood Hits	747	Target Neighborhood Hits	592	Shared Neighborhood Hits	131
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ITSN1_HUMAN
NC score	0.044064 (rank : 839)	θ value	1.06291 (rank : 502)
Query Neighborhood Hits	747	Target Neighborhood Hits	1757	Shared Neighborhood Hits	164
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SF3B1_MOUSE
NC score	0.044048 (rank : 840)	θ value	1.81305 (rank : 553)
Query Neighborhood Hits	747	Target Neighborhood Hits	352	Shared Neighborhood Hits	75
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.043559 (rank : 841)	θ value	1.81305 (rank : 552)
Query Neighborhood Hits	747	Target Neighborhood Hits	341	Shared Neighborhood Hits	73
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CBX2_HUMAN
NC score	0.043435 (rank : 842)	θ value	1.38821 (rank : 526)
Query Neighborhood Hits	747	Target Neighborhood Hits	264	Shared Neighborhood Hits	65
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

GTSE1_HUMAN
NC score	0.043095 (rank : 843)	θ value	5.27518 (rank : 651)
Query Neighborhood Hits	747	Target Neighborhood Hits	193	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

LR37A_HUMAN
NC score	0.043072 (rank : 844)	θ value	1.38821 (rank : 533)
Query Neighborhood Hits	747	Target Neighborhood Hits	720	Shared Neighborhood Hits	115
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SPEG_MOUSE
NC score	0.043004 (rank : 845)	θ value	0.813845 (rank : 488)
Query Neighborhood Hits	747	Target Neighborhood Hits	1959	Shared Neighborhood Hits	229
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PHC2_HUMAN
NC score	0.042817 (rank : 846)	θ value	2.36792 (rank : 576)
Query Neighborhood Hits	747	Target Neighborhood Hits	388	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

HGS_MOUSE
NC score	0.042630 (rank : 847)	θ value	6.88961 (rank : 681)
Query Neighborhood Hits	747	Target Neighborhood Hits	589	Shared Neighborhood Hits	88
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
NC score	0.042624 (rank : 848)	θ value	4.03905 (rank : 618)
Query Neighborhood Hits	747	Target Neighborhood Hits	517	Shared Neighborhood Hits	70
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

GRAP2_MOUSE
NC score	0.042469 (rank : 849)	θ value	0.813845 (rank : 480)
Query Neighborhood Hits	747	Target Neighborhood Hits	297	Shared Neighborhood Hits	56
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP2_HUMAN
NC score	0.042379 (rank : 850)	θ value	0.813845 (rank : 479)
Query Neighborhood Hits	747	Target Neighborhood Hits	304	Shared Neighborhood Hits	59
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

JIP1_HUMAN
NC score	0.042026 (rank : 851)	θ value	1.81305 (rank : 546)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

TENX_HUMAN
NC score	0.041990 (rank : 852)	θ value	0.62314 (rank : 462)
Query Neighborhood Hits	747	Target Neighborhood Hits	789	Shared Neighborhood Hits	66
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NUMBL_HUMAN
NC score	0.041980 (rank : 853)	θ value	4.03905 (rank : 631)
Query Neighborhood Hits	747	Target Neighborhood Hits	394	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

EPN3_MOUSE
NC score	0.041825 (rank : 854)	θ value	0.0961366 (rank : 384)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	72
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

CD2_HUMAN
NC score	0.041792 (rank : 855)	θ value	8.99809 (rank : 707)
Query Neighborhood Hits	747	Target Neighborhood Hits	504	Shared Neighborhood Hits	81
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

JIP1_MOUSE
NC score	0.041370 (rank : 856)	θ value	1.06291 (rank : 505)
Query Neighborhood Hits	747	Target Neighborhood Hits	259	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

CGRE1_HUMAN
NC score	0.040757 (rank : 857)	θ value	0.813845 (rank : 473)
Query Neighborhood Hits	747	Target Neighborhood Hits	354	Shared Neighborhood Hits	61
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

LIPS_HUMAN
NC score	0.040530 (rank : 858)	θ value	1.38821 (rank : 532)
Query Neighborhood Hits	747	Target Neighborhood Hits	314	Shared Neighborhood Hits	90
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

SPEG_HUMAN
NC score	0.040435 (rank : 859)	θ value	0.21417 (rank : 409)
Query Neighborhood Hits	747	Target Neighborhood Hits	1762	Shared Neighborhood Hits	244
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ULK1_HUMAN
NC score	0.040414 (rank : 860)	θ value	5.27518 (rank : 665)
Query Neighborhood Hits	747	Target Neighborhood Hits	1121	Shared Neighborhood Hits	132
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

TACC3_HUMAN
NC score	0.040184 (rank : 861)	θ value	3.0926 (rank : 604)
Query Neighborhood Hits	747	Target Neighborhood Hits	779	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

LRSM1_HUMAN
NC score	0.040133 (rank : 862)	θ value	3.0926 (rank : 597)
Query Neighborhood Hits	747	Target Neighborhood Hits	1078	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ITSN2_MOUSE
NC score	0.040045 (rank : 863)	θ value	1.06291 (rank : 504)
Query Neighborhood Hits	747	Target Neighborhood Hits	1371	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PAK4_MOUSE
NC score	0.040034 (rank : 864)	θ value	0.21417 (rank : 408)
Query Neighborhood Hits	747	Target Neighborhood Hits	1098	Shared Neighborhood Hits	143
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

TCF20_HUMAN
NC score	0.039835 (rank : 865)	θ value	0.62314 (rank : 461)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CRK_HUMAN
NC score	0.039828 (rank : 866)	θ value	6.88961 (rank : 676)
Query Neighborhood Hits	747	Target Neighborhood Hits	308	Shared Neighborhood Hits	57
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CO9A1_HUMAN
NC score	0.038996 (rank : 867)	θ value	0.813845 (rank : 474)
Query Neighborhood Hits	747	Target Neighborhood Hits	420	Shared Neighborhood Hits	98
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

JADE2_MOUSE
NC score	0.038845 (rank : 868)	θ value	0.47712 (rank : 441)
Query Neighborhood Hits	747	Target Neighborhood Hits	560	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

GNAS1_MOUSE
NC score	0.038543 (rank : 869)	θ value	0.279714 (rank : 416)
Query Neighborhood Hits	747	Target Neighborhood Hits	651	Shared Neighborhood Hits	127
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CO9A1_MOUSE
NC score	0.038455 (rank : 870)	θ value	0.0330416 (rank : 348)
Query Neighborhood Hits	747	Target Neighborhood Hits	477	Shared Neighborhood Hits	101
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

PER3_HUMAN
NC score	0.038359 (rank : 871)	θ value	5.27518 (rank : 656)
Query Neighborhood Hits	747	Target Neighborhood Hits	479	Shared Neighborhood Hits	98
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

BAZ2A_HUMAN
NC score	0.038339 (rank : 872)	θ value	0.62314 (rank : 452)
Query Neighborhood Hits	747	Target Neighborhood Hits	780	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

COBA2_MOUSE
NC score	0.038270 (rank : 873)	θ value	4.03905 (rank : 612)
Query Neighborhood Hits	747	Target Neighborhood Hits	501	Shared Neighborhood Hits	127
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CRKL_HUMAN
NC score	0.038175 (rank : 874)	θ value	3.0926 (rank : 591)
Query Neighborhood Hits	747	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

BTBDC_HUMAN
NC score	0.038030 (rank : 875)	θ value	6.88961 (rank : 670)
Query Neighborhood Hits	747	Target Neighborhood Hits	248	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

ZIM10_HUMAN
NC score	0.037831 (rank : 876)	θ value	1.38821 (rank : 539)
Query Neighborhood Hits	747	Target Neighborhood Hits	577	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ASXL1_HUMAN
NC score	0.037792 (rank : 877)	θ value	0.21417 (rank : 405)
Query Neighborhood Hits	747	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

RUSC2_MOUSE
NC score	0.037736 (rank : 878)	θ value	8.99809 (rank : 727)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	91
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CONA1_MOUSE
NC score	0.037604 (rank : 879)	θ value	1.38821 (rank : 528)
Query Neighborhood Hits	747	Target Neighborhood Hits	254	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

LTBP2_MOUSE
NC score	0.037555 (rank : 880)	θ value	6.88961 (rank : 686)
Query Neighborhood Hits	747	Target Neighborhood Hits	617	Shared Neighborhood Hits	63
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ARHG6_MOUSE
NC score	0.037534 (rank : 881)	θ value	6.88961 (rank : 668)
Query Neighborhood Hits	747	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

CEND_HUMAN
NC score	0.037317 (rank : 882)	θ value	4.03905 (rank : 611)
Query Neighborhood Hits	747	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

GRB2_HUMAN
NC score	0.037294 (rank : 883)	θ value	2.36792 (rank : 569)
Query Neighborhood Hits	747	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

ZAR1_MOUSE
NC score	0.037277 (rank : 884)	θ value	2.36792 (rank : 586)
Query Neighborhood Hits	747	Target Neighborhood Hits	254	Shared Neighborhood Hits	48
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CD248_MOUSE
NC score	0.037151 (rank : 885)	θ value	3.0926 (rank : 587)
Query Neighborhood Hits	747	Target Neighborhood Hits	578	Shared Neighborhood Hits	79
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ITSN2_HUMAN
NC score	0.037053 (rank : 886)	θ value	1.06291 (rank : 503)
Query Neighborhood Hits	747	Target Neighborhood Hits	1173	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CRKL_MOUSE
NC score	0.036916 (rank : 887)	θ value	3.0926 (rank : 592)
Query Neighborhood Hits	747	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SPAG8_HUMAN
NC score	0.036914 (rank : 888)	θ value	6.88961 (rank : 695)
Query Neighborhood Hits	747	Target Neighborhood Hits	56	Shared Neighborhood Hits	25
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

GRB2_MOUSE
NC score	0.036345 (rank : 889)	θ value	4.03905 (rank : 616)
Query Neighborhood Hits	747	Target Neighborhood Hits	312	Shared Neighborhood Hits	51
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

ZIM10_MOUSE
NC score	0.036277 (rank : 890)	θ value	1.38821 (rank : 540)
Query Neighborhood Hits	747	Target Neighborhood Hits	430	Shared Neighborhood Hits	87
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MYLK_MOUSE
NC score	0.036208 (rank : 891)	θ value	2.36792 (rank : 572)
Query Neighborhood Hits	747	Target Neighborhood Hits	1489	Shared Neighborhood Hits	136
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

JIP3_HUMAN
NC score	0.036091 (rank : 892)	θ value	0.813845 (rank : 482)
Query Neighborhood Hits	747	Target Neighborhood Hits	1039	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CONA1_HUMAN
NC score	0.035829 (rank : 893)	θ value	0.47712 (rank : 438)
Query Neighborhood Hits	747	Target Neighborhood Hits	281	Shared Neighborhood Hits	87
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CO9A3_HUMAN
NC score	0.035824 (rank : 894)	θ value	6.88961 (rank : 675)
Query Neighborhood Hits	747	Target Neighborhood Hits	361	Shared Neighborhood Hits	95
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

BANK1_MOUSE
NC score	0.035745 (rank : 895)	θ value	4.03905 (rank : 609)
Query Neighborhood Hits	747	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

COJA1_HUMAN
NC score	0.035593 (rank : 896)	θ value	3.0926 (rank : 590)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	86
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

LSD1_HUMAN
NC score	0.034933 (rank : 897)	θ value	1.38821 (rank : 534)
Query Neighborhood Hits	747	Target Neighborhood Hits	455	Shared Neighborhood Hits	73
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AAK1_HUMAN
NC score	0.034856 (rank : 898)	θ value	1.38821 (rank : 523)
Query Neighborhood Hits	747	Target Neighborhood Hits	1077	Shared Neighborhood Hits	136
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ATX7_MOUSE
NC score	0.034737 (rank : 899)	θ value	0.813845 (rank : 468)
Query Neighborhood Hits	747	Target Neighborhood Hits	328	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

AAK1_MOUSE
NC score	0.034619 (rank : 900)	θ value	1.06291 (rank : 491)
Query Neighborhood Hits	747	Target Neighborhood Hits	1051	Shared Neighborhood Hits	127
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

OBF1_HUMAN
NC score	0.034043 (rank : 901)	θ value	0.47712 (rank : 445)
Query Neighborhood Hits	747	Target Neighborhood Hits	203	Shared Neighborhood Hits	43
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

SEPT9_HUMAN
NC score	0.033304 (rank : 902)	θ value	1.06291 (rank : 516)
Query Neighborhood Hits	747	Target Neighborhood Hits	706	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

LEUK_MOUSE
NC score	0.033201 (rank : 903)	θ value	4.03905 (rank : 626)
Query Neighborhood Hits	747	Target Neighborhood Hits	147	Shared Neighborhood Hits	33
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MYO15_HUMAN
NC score	0.032933 (rank : 904)	θ value	0.163984 (rank : 397)
Query Neighborhood Hits	747	Target Neighborhood Hits	671	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

HIRP3_HUMAN
NC score	0.032838 (rank : 905)	θ value	1.38821 (rank : 531)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

MAGD4_HUMAN
NC score	0.032798 (rank : 906)	θ value	0.47712 (rank : 444)
Query Neighborhood Hits	747	Target Neighborhood Hits	338	Shared Neighborhood Hits	70
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

PEX13_MOUSE
NC score	0.032739 (rank : 907)	θ value	0.279714 (rank : 420)
Query Neighborhood Hits	747	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_HUMAN
NC score	0.032726 (rank : 908)	θ value	0.813845 (rank : 486)
Query Neighborhood Hits	747	Target Neighborhood Hits	128	Shared Neighborhood Hits	32
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

MAST1_HUMAN
NC score	0.032202 (rank : 909)	θ value	1.06291 (rank : 508)
Query Neighborhood Hits	747	Target Neighborhood Hits	1146	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

CUTL2_HUMAN
NC score	0.032117 (rank : 910)	θ value	0.365318 (rank : 424)
Query Neighborhood Hits	747	Target Neighborhood Hits	906	Shared Neighborhood Hits	105
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

C2TA_HUMAN
NC score	0.031880 (rank : 911)	θ value	0.62314 (rank : 453)
Query Neighborhood Hits	747	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

INP5E_HUMAN
NC score	0.031717 (rank : 912)	θ value	1.06291 (rank : 501)
Query Neighborhood Hits	747	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

UBP42_HUMAN
NC score	0.031535 (rank : 913)	θ value	0.125558 (rank : 395)
Query Neighborhood Hits	747	Target Neighborhood Hits	445	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

SPR1A_MOUSE
NC score	0.031521 (rank : 914)	θ value	4.03905 (rank : 636)
Query Neighborhood Hits	747	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

LIPA1_HUMAN
NC score	0.031494 (rank : 915)	θ value	6.88961 (rank : 684)
Query Neighborhood Hits	747	Target Neighborhood Hits	1294	Shared Neighborhood Hits	86
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

NRX2B_HUMAN
NC score	0.031393 (rank : 916)	θ value	2.36792 (rank : 575)
Query Neighborhood Hits	747	Target Neighborhood Hits	481	Shared Neighborhood Hits	82
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

EPN2_HUMAN
NC score	0.031264 (rank : 917)	θ value	0.0736092 (rank : 378)
Query Neighborhood Hits	747	Target Neighborhood Hits	156	Shared Neighborhood Hits	44
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

AHI1_HUMAN
NC score	0.031188 (rank : 918)	θ value	8.99809 (rank : 703)
Query Neighborhood Hits	747	Target Neighborhood Hits	537	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

HAIR_HUMAN
NC score	0.030967 (rank : 919)	θ value	0.47712 (rank : 440)
Query Neighborhood Hits	747	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

TAB3_MOUSE
NC score	0.030946 (rank : 920)	θ value	8.99809 (rank : 736)
Query Neighborhood Hits	747	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

OBSCN_HUMAN
NC score	0.030912 (rank : 921)	θ value	0.163984 (rank : 399)
Query Neighborhood Hits	747	Target Neighborhood Hits	1931	Shared Neighborhood Hits	194
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

MAST1_MOUSE
NC score	0.030849 (rank : 922)	θ value	1.38821 (rank : 535)
Query Neighborhood Hits	747	Target Neighborhood Hits	1123	Shared Neighborhood Hits	113
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

GR65_HUMAN
NC score	0.030502 (rank : 923)	θ value	2.36792 (rank : 568)
Query Neighborhood Hits	747	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

LPP_HUMAN
NC score	0.030379 (rank : 924)	θ value	0.47712 (rank : 443)
Query Neighborhood Hits	747	Target Neighborhood Hits	775	Shared Neighborhood Hits	120
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CO4A2_HUMAN
NC score	0.030263 (rank : 925)	θ value	6.88961 (rank : 674)
Query Neighborhood Hits	747	Target Neighborhood Hits	454	Shared Neighborhood Hits	100
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

PKHG4_HUMAN
NC score	0.029898 (rank : 926)	θ value	0.0563607 (rank : 370)
Query Neighborhood Hits	747	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

CRSP7_HUMAN
NC score	0.029869 (rank : 927)	θ value	1.38821 (rank : 529)
Query Neighborhood Hits	747	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

MYO15_MOUSE
NC score	0.029650 (rank : 928)	θ value	0.0330416 (rank : 353)
Query Neighborhood Hits	747	Target Neighborhood Hits	467	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

K2027_HUMAN
NC score	0.029628 (rank : 929)	θ value	1.81305 (rank : 547)
Query Neighborhood Hits	747	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

AKAP2_HUMAN
NC score	0.029539 (rank : 930)	θ value	2.36792 (rank : 556)
Query Neighborhood Hits	747	Target Neighborhood Hits	507	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MK15_HUMAN
NC score	0.029409 (rank : 931)	θ value	1.38821 (rank : 536)
Query Neighborhood Hits	747	Target Neighborhood Hits	1038	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MY18B_HUMAN
NC score	0.029167 (rank : 932)	θ value	2.36792 (rank : 571)
Query Neighborhood Hits	747	Target Neighborhood Hits	1299	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYO9B_HUMAN
NC score	0.029111 (rank : 933)	θ value	0.0193708 (rank : 333)
Query Neighborhood Hits	747	Target Neighborhood Hits	641	Shared Neighborhood Hits	114
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CENPF_HUMAN
NC score	0.029086 (rank : 934)	θ value	0.47712 (rank : 437)
Query Neighborhood Hits	747	Target Neighborhood Hits	1932	Shared Neighborhood Hits	103
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CO4A2_MOUSE
NC score	0.028927 (rank : 935)	θ value	2.36792 (rank : 560)
Query Neighborhood Hits	747	Target Neighborhood Hits	492	Shared Neighborhood Hits	105
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

DLG5_HUMAN
NC score	0.028757 (rank : 936)	θ value	2.36792 (rank : 563)
Query Neighborhood Hits	747	Target Neighborhood Hits	1088	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GOG8A_HUMAN
NC score	0.028375 (rank : 937)	θ value	1.81305 (rank : 545)
Query Neighborhood Hits	747	Target Neighborhood Hits	635	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

ATF2_HUMAN
NC score	0.028147 (rank : 938)	θ value	4.03905 (rank : 607)
Query Neighborhood Hits	747	Target Neighborhood Hits	402	Shared Neighborhood Hits	55
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

NADAP_HUMAN
NC score	0.028099 (rank : 939)	θ value	0.813845 (rank : 484)
Query Neighborhood Hits	747	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

K0423_HUMAN
NC score	0.028072 (rank : 940)	θ value	0.47712 (rank : 442)
Query Neighborhood Hits	747	Target Neighborhood Hits	171	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

NRX2A_HUMAN
NC score	0.027866 (rank : 941)	θ value	2.36792 (rank : 574)
Query Neighborhood Hits	747	Target Neighborhood Hits	614	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

3BP2_MOUSE
NC score	0.027729 (rank : 942)	θ value	5.27518 (rank : 640)
Query Neighborhood Hits	747	Target Neighborhood Hits	142	Shared Neighborhood Hits	37
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

TSC1_HUMAN
NC score	0.027683 (rank : 943)	θ value	0.62314 (rank : 464)
Query Neighborhood Hits	747	Target Neighborhood Hits	765	Shared Neighborhood Hits	63
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

CAC1G_HUMAN
NC score	0.027654 (rank : 944)	θ value	0.125558 (rank : 388)
Query Neighborhood Hits	747	Target Neighborhood Hits	587	Shared Neighborhood Hits	100
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TBCD4_MOUSE
NC score	0.027579 (rank : 945)	θ value	0.813845 (rank : 489)
Query Neighborhood Hits	747	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TXLNB_MOUSE
NC score	0.027542 (rank : 946)	θ value	8.99809 (rank : 742)
Query Neighborhood Hits	747	Target Neighborhood Hits	640	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

UBN1_HUMAN
NC score	0.027301 (rank : 947)	θ value	5.27518 (rank : 663)
Query Neighborhood Hits	747	Target Neighborhood Hits	170	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

ATF2_MOUSE
NC score	0.027298 (rank : 948)	θ value	4.03905 (rank : 608)
Query Neighborhood Hits	747	Target Neighborhood Hits	397	Shared Neighborhood Hits	57
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

MAML3_HUMAN
NC score	0.027285 (rank : 949)	θ value	8.99809 (rank : 721)
Query Neighborhood Hits	747	Target Neighborhood Hits	323	Shared Neighborhood Hits	67
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

DNMT1_HUMAN
NC score	0.027068 (rank : 950)	θ value	8.99809 (rank : 711)
Query Neighborhood Hits	747	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SPHK2_HUMAN
NC score	0.026612 (rank : 951)	θ value	4.03905 (rank : 635)
Query Neighborhood Hits	747	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

DOCK4_HUMAN
NC score	0.025615 (rank : 952)	θ value	0.62314 (rank : 454)
Query Neighborhood Hits	747	Target Neighborhood Hits	237	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

CEP68_HUMAN
NC score	0.025194 (rank : 953)	θ value	0.813845 (rank : 472)
Query Neighborhood Hits	747	Target Neighborhood Hits	128	Shared Neighborhood Hits	29
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

BIM_MOUSE
NC score	0.025015 (rank : 954)	θ value	2.36792 (rank : 557)
Query Neighborhood Hits	747	Target Neighborhood Hits	124	Shared Neighborhood Hits	30
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

ZMYM3_HUMAN
NC score	0.024986 (rank : 955)	θ value	8.99809 (rank : 746)
Query Neighborhood Hits	747	Target Neighborhood Hits	223	Shared Neighborhood Hits	49
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

TPO_MOUSE
NC score	0.024734 (rank : 956)	θ value	5.27518 (rank : 661)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	37
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

DCC_MOUSE
NC score	0.024499 (rank : 957)	θ value	1.81305 (rank : 542)
Query Neighborhood Hits	747	Target Neighborhood Hits	896	Shared Neighborhood Hits	106
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

NBR1_MOUSE
NC score	0.024263 (rank : 958)	θ value	2.36792 (rank : 573)
Query Neighborhood Hits	747	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

NUFP1_HUMAN
NC score	0.023877 (rank : 959)	θ value	1.06291 (rank : 509)
Query Neighborhood Hits	747	Target Neighborhood Hits	193	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

MYO1F_HUMAN
NC score	0.023820 (rank : 960)	θ value	1.81305 (rank : 548)
Query Neighborhood Hits	747	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

PMYT1_HUMAN
NC score	0.023437 (rank : 961)	θ value	8.99809 (rank : 724)
Query Neighborhood Hits	747	Target Neighborhood Hits	814	Shared Neighborhood Hits	61
SwissProt Accessions	Q99640, O14731, Q7LE24, Q8TCM9	Gene names	PKMYT1, MYT1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

RP3A_MOUSE
NC score	0.022998 (rank : 962)	θ value	5.27518 (rank : 657)
Query Neighborhood Hits	747	Target Neighborhood Hits	510	Shared Neighborhood Hits	105
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

NCOR1_HUMAN
NC score	0.022898 (rank : 963)	θ value	4.03905 (rank : 629)
Query Neighborhood Hits	747	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

DOCK4_MOUSE
NC score	0.022663 (rank : 964)	θ value	0.365318 (rank : 426)
Query Neighborhood Hits	747	Target Neighborhood Hits	210	Shared Neighborhood Hits	52
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

SYNG_MOUSE
NC score	0.022075 (rank : 965)	θ value	5.27518 (rank : 660)
Query Neighborhood Hits	747	Target Neighborhood Hits	206	Shared Neighborhood Hits	38
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

NCOA2_HUMAN
NC score	0.021578 (rank : 966)	θ value	3.0926 (rank : 599)
Query Neighborhood Hits	747	Target Neighborhood Hits	281	Shared Neighborhood Hits	44
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

DEND_HUMAN
NC score	0.021555 (rank : 967)	θ value	2.36792 (rank : 561)
Query Neighborhood Hits	747	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

DOK7_MOUSE
NC score	0.021550 (rank : 968)	θ value	2.36792 (rank : 564)
Query Neighborhood Hits	747	Target Neighborhood Hits	169	Shared Neighborhood Hits	39
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

TINF2_HUMAN
NC score	0.021169 (rank : 969)	θ value	4.03905 (rank : 638)
Query Neighborhood Hits	747	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

DDX51_HUMAN
NC score	0.021097 (rank : 970)	θ value	0.000158464 (rank : 252)
Query Neighborhood Hits	747	Target Neighborhood Hits	332	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

SPHK2_MOUSE
NC score	0.021053 (rank : 971)	θ value	1.06291 (rank : 517)
Query Neighborhood Hits	747	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

PAF49_MOUSE
NC score	0.021037 (rank : 972)	θ value	0.62314 (rank : 459)
Query Neighborhood Hits	747	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

HN1L_HUMAN
NC score	0.020909 (rank : 973)	θ value	4.03905 (rank : 619)
Query Neighborhood Hits	747	Target Neighborhood Hits	88	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

FOG1_HUMAN
NC score	0.020517 (rank : 974)	θ value	0.279714 (rank : 415)
Query Neighborhood Hits	747	Target Neighborhood Hits	981	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SYNE2_HUMAN
NC score	0.020487 (rank : 975)	θ value	3.0926 (rank : 603)
Query Neighborhood Hits	747	Target Neighborhood Hits	1323	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

AFF3_HUMAN
NC score	0.020192 (rank : 976)	θ value	8.99809 (rank : 702)
Query Neighborhood Hits	747	Target Neighborhood Hits	190	Shared Neighborhood Hits	43
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

FBX46_MOUSE
NC score	0.020071 (rank : 977)	θ value	0.813845 (rank : 476)
Query Neighborhood Hits	747	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

LRC56_HUMAN
NC score	0.019790 (rank : 978)	θ value	5.27518 (rank : 653)
Query Neighborhood Hits	747	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

OSBL5_HUMAN
NC score	0.019682 (rank : 979)	θ value	5.27518 (rank : 655)
Query Neighborhood Hits	747	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

FOG1_MOUSE
NC score	0.019496 (rank : 980)	θ value	5.27518 (rank : 649)
Query Neighborhood Hits	747	Target Neighborhood Hits	1237	Shared Neighborhood Hits	171
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PK1L1_HUMAN
NC score	0.019023 (rank : 981)	θ value	1.81305 (rank : 551)
Query Neighborhood Hits	747	Target Neighborhood Hits	140	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PHLPP_HUMAN
NC score	0.018997 (rank : 982)	θ value	8.99809 (rank : 723)
Query Neighborhood Hits	747	Target Neighborhood Hits	604	Shared Neighborhood Hits	104
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

UBP53_MOUSE
NC score	0.018377 (rank : 983)	θ value	2.36792 (rank : 585)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

SOX13_MOUSE
NC score	0.018347 (rank : 984)	θ value	2.36792 (rank : 581)
Query Neighborhood Hits	747	Target Neighborhood Hits	495	Shared Neighborhood Hits	61
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SHC2_HUMAN
NC score	0.018337 (rank : 985)	θ value	6.88961 (rank : 692)
Query Neighborhood Hits	747	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

TTC28_HUMAN
NC score	0.018279 (rank : 986)	θ value	4.03905 (rank : 639)
Query Neighborhood Hits	747	Target Neighborhood Hits	271	Shared Neighborhood Hits	43
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ZN409_HUMAN
NC score	0.017911 (rank : 987)	θ value	0.279714 (rank : 422)
Query Neighborhood Hits	747	Target Neighborhood Hits	842	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

HAIR_MOUSE
NC score	0.017634 (rank : 988)	θ value	6.88961 (rank : 680)
Query Neighborhood Hits	747	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

RFIP1_MOUSE
NC score	0.017445 (rank : 989)	θ value	2.36792 (rank : 578)
Query Neighborhood Hits	747	Target Neighborhood Hits	152	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

GP152_HUMAN
NC score	0.017301 (rank : 990)	θ value	8.99809 (rank : 714)
Query Neighborhood Hits	747	Target Neighborhood Hits	636	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

PAR6A_HUMAN
NC score	0.017099 (rank : 991)	θ value	0.279714 (rank : 419)
Query Neighborhood Hits	747	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

FGFP3_HUMAN
NC score	0.016779 (rank : 992)	θ value	3.0926 (rank : 593)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

CBX4_MOUSE
NC score	0.016594 (rank : 993)	θ value	1.06291 (rank : 498)
Query Neighborhood Hits	747	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

TLE1_HUMAN
NC score	0.016199 (rank : 994)	θ value	0.47712 (rank : 448)
Query Neighborhood Hits	747	Target Neighborhood Hits	485	Shared Neighborhood Hits	62
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

ARHG1_MOUSE
NC score	0.016080 (rank : 995)	θ value	5.27518 (rank : 641)
Query Neighborhood Hits	747	Target Neighborhood Hits	266	Shared Neighborhood Hits	60
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

FOXN1_HUMAN
NC score	0.016003 (rank : 996)	θ value	3.0926 (rank : 594)
Query Neighborhood Hits	747	Target Neighborhood Hits	377	Shared Neighborhood Hits	63
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

FRS3_HUMAN
NC score	0.015839 (rank : 997)	θ value	3.0926 (rank : 595)
Query Neighborhood Hits	747	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

TLE1_MOUSE
NC score	0.015637 (rank : 998)	θ value	0.21417 (rank : 411)
Query Neighborhood Hits	747	Target Neighborhood Hits	491	Shared Neighborhood Hits	62
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

SI1L3_HUMAN
NC score	0.015454 (rank : 999)	θ value	6.88961 (rank : 693)
Query Neighborhood Hits	747	Target Neighborhood Hits	305	Shared Neighborhood Hits	60
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

C1QA_HUMAN
NC score	0.015431 (rank : 1000)	θ value	1.38821 (rank : 525)
Query Neighborhood Hits	747	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

ADA12_MOUSE
NC score	0.014938 (rank : 1001)	θ value	0.47712 (rank : 433)
Query Neighborhood Hits	747	Target Neighborhood Hits	474	Shared Neighborhood Hits	72
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

UBP43_HUMAN
NC score	0.014503 (rank : 1002)	θ value	0.365318 (rank : 432)
Query Neighborhood Hits	747	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

SEM6B_MOUSE
NC score	0.014467 (rank : 1003)	θ value	0.0563607 (rank : 371)
Query Neighborhood Hits	747	Target Neighborhood Hits	200	Shared Neighborhood Hits	45
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

B4GT1_HUMAN
NC score	0.014453 (rank : 1004)	θ value	0.0736092 (rank : 375)
Query Neighborhood Hits	747	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

FOXN1_MOUSE
NC score	0.014309 (rank : 1005)	θ value	2.36792 (rank : 565)
Query Neighborhood Hits	747	Target Neighborhood Hits	300	Shared Neighborhood Hits	51
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GMIP_HUMAN
NC score	0.014125 (rank : 1006)	θ value	8.99809 (rank : 713)
Query Neighborhood Hits	747	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

MARCO_MOUSE
NC score	0.014031 (rank : 1007)	θ value	3.0926 (rank : 598)
Query Neighborhood Hits	747	Target Neighborhood Hits	242	Shared Neighborhood Hits	35
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

SAMD4_MOUSE
NC score	0.013982 (rank : 1008)	θ value	8.99809 (rank : 729)
Query Neighborhood Hits	747	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

PP2CG_MOUSE
NC score	0.013574 (rank : 1009)	θ value	3.0926 (rank : 600)
Query Neighborhood Hits	747	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

IRS1_HUMAN
NC score	0.013483 (rank : 1010)	θ value	6.88961 (rank : 683)
Query Neighborhood Hits	747	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

ZN687_HUMAN
NC score	0.013430 (rank : 1011)	θ value	0.62314 (rank : 466)
Query Neighborhood Hits	747	Target Neighborhood Hits	1244	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

UB7I1_MOUSE
NC score	0.013306 (rank : 1012)	θ value	5.27518 (rank : 662)
Query Neighborhood Hits	747	Target Neighborhood Hits	206	Shared Neighborhood Hits	40
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

P2RX2_HUMAN
NC score	0.013239 (rank : 1013)	θ value	0.813845 (rank : 485)
Query Neighborhood Hits	747	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

SEZ6L_HUMAN
NC score	0.012844 (rank : 1014)	θ value	1.38821 (rank : 538)
Query Neighborhood Hits	747	Target Neighborhood Hits	289	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

IPPD_MOUSE
NC score	0.012794 (rank : 1015)	θ value	6.88961 (rank : 682)
Query Neighborhood Hits	747	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60829, Q91XB5	Gene names	Ppp1r1b
Domain Architecture	No domain graphic available
Description	Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32).

DNM3A_MOUSE
NC score	0.012234 (rank : 1016)	θ value	4.03905 (rank : 613)
Query Neighborhood Hits	747	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

HLF_MOUSE
NC score	0.012191 (rank : 1017)	θ value	2.36792 (rank : 570)
Query Neighborhood Hits	747	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

DOK2_MOUSE
NC score	0.012086 (rank : 1018)	θ value	4.03905 (rank : 614)
Query Neighborhood Hits	747	Target Neighborhood Hits	244	Shared Neighborhood Hits	33
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

FREA_HUMAN
NC score	0.012051 (rank : 1019)	θ value	6.88961 (rank : 679)
Query Neighborhood Hits	747	Target Neighborhood Hits	205	Shared Neighborhood Hits	41
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

CAC1H_MOUSE
NC score	0.011075 (rank : 1020)	θ value	1.06291 (rank : 497)
Query Neighborhood Hits	747	Target Neighborhood Hits	230	Shared Neighborhood Hits	39
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

TLE4_MOUSE
NC score	0.010774 (rank : 1021)	θ value	8.99809 (rank : 740)
Query Neighborhood Hits	747	Target Neighborhood Hits	482	Shared Neighborhood Hits	58
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.010356 (rank : 1022)	θ value	8.99809 (rank : 739)
Query Neighborhood Hits	747	Target Neighborhood Hits	477	Shared Neighborhood Hits	56
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

PDLI7_HUMAN
NC score	0.009832 (rank : 1023)	θ value	1.81305 (rank : 550)
Query Neighborhood Hits	747	Target Neighborhood Hits	547	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SAMD4_HUMAN
NC score	0.009798 (rank : 1024)	θ value	8.99809 (rank : 728)
Query Neighborhood Hits	747	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SKI_HUMAN
NC score	0.009681 (rank : 1025)	θ value	6.88961 (rank : 694)
Query Neighborhood Hits	747	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

GP124_MOUSE
NC score	0.009520 (rank : 1026)	θ value	0.0113563 (rank : 319)
Query Neighborhood Hits	747	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

TDRD6_MOUSE
NC score	0.009401 (rank : 1027)	θ value	2.36792 (rank : 583)
Query Neighborhood Hits	747	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

MYCL1_HUMAN
NC score	0.009160 (rank : 1028)	θ value	4.03905 (rank : 628)
Query Neighborhood Hits	747	Target Neighborhood Hits	146	Shared Neighborhood Hits	21
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

TAF1C_MOUSE
NC score	0.009134 (rank : 1029)	θ value	8.99809 (rank : 737)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

TLE3_HUMAN
NC score	0.009029 (rank : 1030)	θ value	8.99809 (rank : 738)
Query Neighborhood Hits	747	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

RT35_HUMAN
NC score	0.008847 (rank : 1031)	θ value	6.88961 (rank : 690)
Query Neighborhood Hits	747	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

EDN3_MOUSE
NC score	0.008647 (rank : 1032)	θ value	5.27518 (rank : 646)
Query Neighborhood Hits	747	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	P48299, Q543L0	Gene names	Edn3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

CHIT1_MOUSE
NC score	0.008574 (rank : 1033)	θ value	0.279714 (rank : 413)
Query Neighborhood Hits	747	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

DLG4_HUMAN
NC score	0.008449 (rank : 1034)	θ value	2.36792 (rank : 562)
Query Neighborhood Hits	747	Target Neighborhood Hits	286	Shared Neighborhood Hits	41
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

HASP_HUMAN
NC score	0.008318 (rank : 1035)	θ value	3.0926 (rank : 596)
Query Neighborhood Hits	747	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TF76, Q5U5K3, Q96MN1, Q9BXS7	Gene names	GSG2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (H-Haspin) (Germ cell-specific gene 2 protein).

FREA_MOUSE
NC score	0.008244 (rank : 1036)	θ value	2.36792 (rank : 566)
Query Neighborhood Hits	747	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

IC1_MOUSE
NC score	0.008219 (rank : 1037)	θ value	0.0330416 (rank : 351)
Query Neighborhood Hits	747	Target Neighborhood Hits	164	Shared Neighborhood Hits	18
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

CAC1A_MOUSE
NC score	0.007935 (rank : 1038)	θ value	4.03905 (rank : 610)
Query Neighborhood Hits	747	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

TLE3_MOUSE
NC score	0.007907 (rank : 1039)	θ value	6.88961 (rank : 697)
Query Neighborhood Hits	747	Target Neighborhood Hits	378	Shared Neighborhood Hits	36
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

FOXH1_HUMAN
NC score	0.007861 (rank : 1040)	θ value	0.813845 (rank : 477)
Query Neighborhood Hits	747	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

DLG1_MOUSE
NC score	0.007743 (rank : 1041)	θ value	5.27518 (rank : 645)
Query Neighborhood Hits	747	Target Neighborhood Hits	285	Shared Neighborhood Hits	44
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

PROP_MOUSE
NC score	0.007026 (rank : 1042)	θ value	1.06291 (rank : 513)
Query Neighborhood Hits	747	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

XKR5_HUMAN
NC score	0.007002 (rank : 1043)	θ value	8.99809 (rank : 743)
Query Neighborhood Hits	747	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

DCBD1_MOUSE
NC score	0.006935 (rank : 1044)	θ value	0.813845 (rank : 475)
Query Neighborhood Hits	747	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

LAP2A_HUMAN
NC score	0.006700 (rank : 1045)	θ value	4.03905 (rank : 625)
Query Neighborhood Hits	747	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

HRSL5_HUMAN
NC score	0.006368 (rank : 1046)	θ value	8.99809 (rank : 715)
Query Neighborhood Hits	747	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

ZN516_MOUSE
NC score	0.006182 (rank : 1047)	θ value	0.0563607 (rank : 374)
Query Neighborhood Hits	747	Target Neighborhood Hits	1197	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ATS14_HUMAN
NC score	0.006146 (rank : 1048)	θ value	6.88961 (rank : 669)
Query Neighborhood Hits	747	Target Neighborhood Hits	382	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

SIM2_HUMAN
NC score	0.006111 (rank : 1049)	θ value	3.0926 (rank : 601)
Query Neighborhood Hits	747	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

DLG4_MOUSE
NC score	0.005973 (rank : 1050)	θ value	8.99809 (rank : 710)
Query Neighborhood Hits	747	Target Neighborhood Hits	282	Shared Neighborhood Hits	42
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GATA5_HUMAN
NC score	0.005962 (rank : 1051)	θ value	1.81305 (rank : 544)
Query Neighborhood Hits	747	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

WWTR1_HUMAN
NC score	0.005735 (rank : 1052)	θ value	3.0926 (rank : 606)
Query Neighborhood Hits	747	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

FOXK2_HUMAN
NC score	0.005684 (rank : 1053)	θ value	5.27518 (rank : 650)
Query Neighborhood Hits	747	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

SEM6B_HUMAN
NC score	0.005659 (rank : 1054)	θ value	8.99809 (rank : 730)
Query Neighborhood Hits	747	Target Neighborhood Hits	187	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

REV1_HUMAN
NC score	0.005614 (rank : 1055)	θ value	6.88961 (rank : 688)
Query Neighborhood Hits	747	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

PJA1_HUMAN
NC score	0.005463 (rank : 1056)	θ value	4.03905 (rank : 632)
Query Neighborhood Hits	747	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

STAT6_HUMAN
NC score	0.005173 (rank : 1057)	θ value	3.0926 (rank : 602)
Query Neighborhood Hits	747	Target Neighborhood Hits	132	Shared Neighborhood Hits	21
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

PUNC_MOUSE
NC score	0.004908 (rank : 1058)	θ value	4.03905 (rank : 634)
Query Neighborhood Hits	747	Target Neighborhood Hits	501	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

HCN1_MOUSE
NC score	0.004764 (rank : 1059)	θ value	4.03905 (rank : 617)
Query Neighborhood Hits	747	Target Neighborhood Hits	172	Shared Neighborhood Hits	25
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

NOS3_HUMAN
NC score	0.004629 (rank : 1060)	θ value	6.88961 (rank : 687)
Query Neighborhood Hits	747	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

DCMC_HUMAN
NC score	0.004199 (rank : 1061)	θ value	8.99809 (rank : 709)
Query Neighborhood Hits	747	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O95822, Q9UNU5, Q9Y3F2	Gene names	MLYCD
Domain Architecture
Description	Malonyl-CoA decarboxylase, mitochondrial precursor (EC 4.1.1.9) (MCD).

UBP49_HUMAN
NC score	0.003298 (rank : 1062)	θ value	5.27518 (rank : 664)
Query Neighborhood Hits	747	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

LNX2_MOUSE
NC score	0.002617 (rank : 1063)	θ value	6.88961 (rank : 685)
Query Neighborhood Hits	747	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

UBP6_HUMAN
NC score	0.002509 (rank : 1064)	θ value	6.88961 (rank : 700)
Query Neighborhood Hits	747	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

SNX25_HUMAN
NC score	0.002159 (rank : 1065)	θ value	8.99809 (rank : 735)
Query Neighborhood Hits	747	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

PAX3_MOUSE
NC score	0.002066 (rank : 1066)	θ value	1.06291 (rank : 510)
Query Neighborhood Hits	747	Target Neighborhood Hits	478	Shared Neighborhood Hits	28
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PAX3_HUMAN
NC score	0.001467 (rank : 1067)	θ value	1.81305 (rank : 549)
Query Neighborhood Hits	747	Target Neighborhood Hits	513	Shared Neighborhood Hits	27
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

ETV4_MOUSE
NC score	0.001178 (rank : 1068)	θ value	8.99809 (rank : 712)
Query Neighborhood Hits	747	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

LRC27_MOUSE
NC score	0.001161 (rank : 1069)	θ value	8.99809 (rank : 720)
Query Neighborhood Hits	747	Target Neighborhood Hits	290	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YS5, Q9D6Z2	Gene names	Lrrc27
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

TSH3_HUMAN
NC score	-0.000193 (rank : 1070)	θ value	8.99809 (rank : 741)
Query Neighborhood Hits	747	Target Neighborhood Hits	564	Shared Neighborhood Hits	31
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

ZHX2_MOUSE
NC score	-0.000522 (rank : 1071)	θ value	8.99809 (rank : 745)
Query Neighborhood Hits	747	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

CCNA2_MOUSE
NC score	-0.000547 (rank : 1072)	θ value	8.99809 (rank : 705)
Query Neighborhood Hits	747	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P51943, Q61459	Gene names	Ccna2, Ccna, Cyca
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

PLRG1_HUMAN
NC score	-0.002179 (rank : 1073)	θ value	4.03905 (rank : 633)
Query Neighborhood Hits	747	Target Neighborhood Hits	318	Shared Neighborhood Hits	17
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

HXB2_MOUSE
NC score	-0.003526 (rank : 1074)	θ value	4.03905 (rank : 621)
Query Neighborhood Hits	747	Target Neighborhood Hits	350	Shared Neighborhood Hits	22
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

HXC10_MOUSE
NC score	-0.005795 (rank : 1075)	θ value	8.99809 (rank : 716)
Query Neighborhood Hits	747	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

HXA2_HUMAN
NC score	-0.006648 (rank : 1076)	θ value	4.03905 (rank : 620)
Query Neighborhood Hits	747	Target Neighborhood Hits	370	Shared Neighborhood Hits	17
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

KLF17_HUMAN
NC score	-0.007000 (rank : 1077)	θ value	1.06291 (rank : 506)
Query Neighborhood Hits	747	Target Neighborhood Hits	882	Shared Neighborhood Hits	72
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

EGR4_HUMAN
NC score	-0.008351 (rank : 1078)	θ value	0.47712 (rank : 439)
Query Neighborhood Hits	747	Target Neighborhood Hits	939	Shared Neighborhood Hits	62
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

GP176_MOUSE
NC score	-0.009561 (rank : 1079)	θ value	2.36792 (rank : 567)
Query Neighborhood Hits	747	Target Neighborhood Hits	539	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

HIC1_MOUSE
NC score	-0.010171 (rank : 1080)	θ value	5.27518 (rank : 652)
Query Neighborhood Hits	747	Target Neighborhood Hits	863	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

ZN335_HUMAN
NC score	-0.010711 (rank : 1081)	θ value	6.88961 (rank : 701)
Query Neighborhood Hits	747	Target Neighborhood Hits	973	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ZSCA5_HUMAN
NC score	-0.011919 (rank : 1082)	θ value	1.06291 (rank : 522)
Query Neighborhood Hits	747	Target Neighborhood Hits	862	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

ZBT38_HUMAN
NC score	-0.012946 (rank : 1083)	θ value	5.27518 (rank : 666)
Query Neighborhood Hits	747	Target Neighborhood Hits	885	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ZN579_HUMAN
NC score	-0.013513 (rank : 1084)	θ value	5.27518 (rank : 667)
Query Neighborhood Hits	747	Target Neighborhood Hits	726	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NAF0	Gene names	ZNF579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

ZBT16_HUMAN
NC score	-0.013747 (rank : 1085)	θ value	8.99809 (rank : 744)
Query Neighborhood Hits	747	Target Neighborhood Hits	1010	Shared Neighborhood Hits	54
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZN710_HUMAN
NC score	-0.014136 (rank : 1086)	θ value	8.99809 (rank : 747)
Query Neighborhood Hits	747	Target Neighborhood Hits	796	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

PRD14_HUMAN
NC score	-0.014476 (rank : 1087)	θ value	8.99809 (rank : 725)
Query Neighborhood Hits	747	Target Neighborhood Hits	757	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).